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Judy A Van De Water

TitlePROF IN RES-HCOMP
InstitutionUniversity of California Davis
DepartmentMED INT MED - RHEUMATOLOGY
AddressGenome and Biomed Sci Fac Bldg
CA 95616
Phone530-752-2154
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    Collapse Research 
    Collapse Research Activities and Funding
    Maternal inflammation during pregnancy and neurodevelopmental disorders
    NIH/NICHD R01HD095128Jul 15, 2018 - May 31, 2023
    Role: Co-Principal Investigator
    Interdisciplinary Investigation of Biological Signatures of Autism Subtypes
    NIH/NIMH R01MH089626Sep 30, 2009 - Aug 31, 2012
    Role: Co-Principal Investigator
    Gene Expression and Immune Cell Function in Mothers of Children with Autism
    NIH/NICHD R21HD065269Sep 30, 2009 - Aug 31, 2011
    Role: Co-Principal Investigator
    The UC Davis Center for Children's Enviromental Health and Disease Prevention
    NIH/NIEHS P01ES011269Sep 30, 2001 - May 31, 2018
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Jones KL, Pride MC, Edmiston E, Yang M, Silverman JL, Crawley JN, Van de Water J. Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism. Mol Psychiatry. 2018 Jun 28. PMID: 29955164.
      View in: PubMed
    2. Jones KL, Van de Water J. Maternal autoantibody related autism: mechanisms and pathways. Mol Psychiatry. 2018 Jun 22. PMID: 29934547.
      View in: PubMed
    3. Lesh TA, Careaga M, Rose DR, McAllister AK, Van de Water J, Carter CS, Ashwood P. Cytokine alterations in first-episode schizophrenia and bipolar disorder: relationships to brain structure and symptoms. J Neuroinflammation. 2018 May 26; 15(1):165. PMID: 29803226.
      View in: PubMed
    4. Rose DR, Yang H, Serena G, Sturgeon C, Ma B, Careaga M, Hughes HK, Angkustsiri K, Rose M, Hertz-Picciotto I, Van de Water J, Hansen RL, Ravel J, Fasano A, Ashwood P. Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms. Brain Behav Immun. 2018 May; 70:354-368. PMID: 29571898.
      View in: PubMed
    5. Edmiston E, Jones KL, Vu T, Ashwood P, Van de Water J. Identification of the antigenic epitopes of maternal autoantibodies in autism spectrum disorders. Brain Behav Immun. 2018 Mar; 69:399-407. PMID: 29289663.
      View in: PubMed
    6. Onore C, Yang H, Van de Water J, Ashwood P. Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder. Front Pediatr. 2017; 5:43. PMID: 28361047.
      View in: PubMed
    7. Amaral DG, Li D, Libero L, Solomon M, Van de Water J, Mastergeorge A, Naigles L, Rogers S, Wu Nordahl C. In pursuit of neurophenotypes: The consequences of having autism and a big brain. Autism Res. 2017 May; 10(5):711-722. PMID: 28239961.
      View in: PubMed
    8. Rose DR, Careaga M, Van de Water J, McAllister K, Bauman MD, Ashwood P. Long-term altered immune responses following fetal priming in a non-human primate model of maternal immune activation. Brain Behav Immun. 2017 Jul; 63:60-70. PMID: 27876552.
      View in: PubMed
    9. Edmiston E, Ashwood P, Van de Water J. Autoimmunity, Autoantibodies, and Autism Spectrum Disorder. Biol Psychiatry. 2017 03 01; 81(5):383-390. PMID: 28340985.
      View in: PubMed
    10. Meltzer A, Van de Water J. The Role of the Immune System in Autism Spectrum Disorder. Neuropsychopharmacology. 2017 01; 42(1):284-298. PMID: 27534269.
      View in: PubMed
    11. Krakowiak P, Walker CK, Tancredi D, Hertz-Picciotto I, Van de Water J. Autism-specific maternal anti-fetal brain autoantibodies are associated with metabolic conditions. Autism Res. 2017 Jan; 10(1):89-98. PMID: 27312731.
      View in: PubMed
    12. Grether JK, Ashwood P, Van de Water J, Yolken RH, Anderson MC, Torres AR, Westover JB, Sweeten T, Hansen RL, Kharrazi M, Croen LA. Prenatal and Newborn Immunoglobulin Levels from Mother-Child Pairs and Risk of Autism Spectrum Disorders. Front Neurosci. 2016; 10:218. PMID: 27242422; PMCID: PMC4870252.
    13. Matelski L, Van de Water J. Risk factors in autism: Thinking outside the brain. J Autoimmun. 2016 Feb; 67:1-7. PMID: 26725748.
      View in: PubMed
    14. Zerbo O, Qian Y, Yoshida C, Grether JK, Van de Water J, Croen LA. Maternal Infection During Pregnancy and Autism Spectrum Disorders. J Autism Dev Disord. 2015 Dec; 45(12):4015-25. PMID: 24366406.
      View in: PubMed
    15. Careaga M, Rogers S, Hansen RL, Amaral DG, Van de Water J, Ashwood P. Immune Endophenotypes in Children With Autism Spectrum Disorder. Biol Psychiatry. 2017 03 01; 81(5):434-441. PMID: 26493496.
      View in: PubMed
    16. Fox-Edmiston E, Van de Water J. Maternal Anti-Fetal Brain IgG Autoantibodies and Autism Spectrum Disorder: Current Knowledge and its Implications for Potential Therapeutics. CNS Drugs. 2015 Sep; 29(9):715-24. PMID: 26369920; PMCID: PMC4605883.
    17. Krakowiak P, Goines PE, Tancredi DJ, Ashwood P, Hansen RL, Hertz-Picciotto I, Van de Water J. Neonatal Cytokine Profiles Associated With Autism Spectrum Disorder. Biol Psychiatry. 2017 03 01; 81(5):442-451. PMID: 26392128.
      View in: PubMed
    18. Vu T, Rahimian A, Stybayeva G, Gao Y, Kwa T, Van de Water J, Revzin A. Reconfigurable microfluidic device with integrated antibody arrays for capture, multiplexed stimulation, and cytokine profiling of human monocytes. Biomicrofluidics. 2015 Jul; 9(4):044115. PMID: 26339315; PMCID: PMC4529433.
    19. Akintunde ME, Rose M, Krakowiak P, Heuer L, Ashwood P, Hansen R, Hertz-Picciotto I, Van de Water J. Increased production of IL-17 in children with autism spectrum disorders and co-morbid asthma. J Neuroimmunol. 2015 Sep 15; 286:33-41. PMID: 26298322; PMCID: PMC4548834.
    20. Sun Y, Haapanen K, Li B, Zhang W, Van de Water J, Gershwin ME. Women and primary biliary cirrhosis. Clin Rev Allergy Immunol. 2015 Jun; 48(2-3):285-300. PMID: 25241227.
      View in: PubMed
    21. Lyall K, Van de Water J, Ashwood P, Hertz-Picciotto I. Asthma and Allergies in Children With Autism Spectrum Disorders: Results From the CHARGE Study. Autism Res. 2015 Oct; 8(5):567-74. PMID: 25722050.
      View in: PubMed
    22. Martínez-Cerdeño V, Camacho J, Fox E, Miller E, Ariza J, Kienzle D, Plank K, Noctor SC, Van de Water J. Prenatal Exposure to Autism-Specific Maternal Autoantibodies Alters Proliferation of Cortical Neural Precursor Cells, Enlarges Brain, and Increases Neuronal Size in Adult Animals. Cereb Cortex. 2016 Jan; 26(1):374-383. PMID: 25535268.
      View in: PubMed
    23. Lyall K, Ashwood P, Van de Water J, Hertz-Picciotto I. Maternal immune-mediated conditions, autism spectrum disorders, and developmental delay. J Autism Dev Disord. 2014 Jul; 44(7):1546-55. PMID: 24337796; PMCID: PMC4104679.
    24. Zerbo O, Yoshida C, Grether JK, Van de Water J, Ashwood P, Delorenze GN, Hansen RL, Kharrazi M, Croen LA. Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study. J Neuroinflammation. 2014 Jun 20; 11:113. PMID: 24951035; PMCID: PMC4080514.
    25. Careaga M, Noyon T, Basuta K, Van de Water J, Tassone F, Hagerman RJ, Ashwood P. Group I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome. J Neuroinflammation. 2014 Jun 19; 11:110. PMID: 24942544.
      View in: PubMed
    26. Careaga M, Hansen RL, Hertz-Piccotto I, Van de Water J, Ashwood P. Increased anti-phospholipid antibodies in autism spectrum disorders. Mediators Inflamm. 2013; 2013:935608. PMID: 24174712; PMCID: PMC3794552.
    27. Rossi CC, Fuentes J, Van de Water J, Amaral DG. Brief Report: Antibodies Reacting to Brain Tissue in Basque Spanish Children with Autism Spectrum Disorder and Their Mothers. J Autism Dev Disord. 2013 Sep 11. PMID: 24022729.
      View in: PubMed
    28. Nordahl CW, Braunschweig D, Iosif AM, Lee A, Rogers S, Ashwood P, Amaral DG, Van de Water J. Maternal autoantibodies are associated with abnormal brain enlargement in a subgroup of children with autism spectrum disorder. Brain Behav Immun. 2013 May; 30:61-5. PMID: 23395715; PMCID: PMC3641177.
    29. Breece E, Paciotti B, Nordahl CW, Ozonoff S, Van de Water JA, Rogers SJ, Amaral D, Ashwood P. Myeloid dendritic cells frequencies are increased in children with autism spectrum disorder and associated with amygdala volume and repetitive behaviors. Brain Behav Immun. 2013 Jul; 31:69-75. PMID: 23063420.
      View in: PubMed
    30. Persico AM, Van de Water J, Pardo CA. Autism: where genetics meets the immune system. Autism Res Treat. 2012; 2012:486359. PMID: 22988503; PMCID: PMC3440848.
    31. Fox E, Amaral D, Van de Water J. Maternal and fetal antibrain antibodies in development and disease. Dev Neurobiol. 2012 Oct; 72(10):1327-34. PMID: 22911883; PMCID: PMC3478666.
    32. Braunschweig D, Golub MS, Koenig CM, Qi L, Pessah IN, Van de Water J, Berman RF. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. J Neuroimmunol. 2012 Nov 15; 252(1-2):56-65. PMID: 22951357; PMCID: PMC4096980.
    33. Winarni TI, Chonchaiya W, Sumekar TA, Ashwood P, Morales GM, Tassone F, Nguyen DV, Faradz SM, Van de Water J, Cook K, Hamlin A, Mu Y, Hagerman PJ, Hagerman RJ. Immune-mediated disorders among women carriers of fragile X premutation alleles. Am J Med Genet A. 2012 Oct; 158A(10):2473-81. PMID: 22903889; PMCID: PMC4105154.
    34. Heuer LS, Rose M, Ashwood P, Van de Water J. Decreased levels of total immunoglobulin in children with autism are not a result of B cell dysfunction. J Neuroimmunol. 2012 Oct 15; 251(1-2):94-102. PMID: 22854260; PMCID: PMC3432686.
    35. Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. J Autism Dev Disord. 2012 Jul; 42(7):1435-45. PMID: 22012245; PMCID: PMC4871696.
    36. Onore CE, Nordahl CW, Young GS, Van de Water JA, Rogers SJ, Ashwood P. Levels of soluble platelet endothelial cell adhesion molecule-1 and P-selectin are decreased in children with autism spectrum disorder. Biol Psychiatry. 2012 Dec 15; 72(12):1020-5. PMID: 22717029.
      View in: PubMed
    37. Braunschweig D, Van de Water J. Maternal autoantibodies in autism. Arch Neurol. 2012 Jun; 69(6):693-9. PMID: 22689191; PMCID: PMC4776649.
    38. Onore C, Van de Water J, Ashwood P. Decreased levels of EGF in plasma of children with autism spectrum disorder. Autism Res Treat. 2012; 2012:205362. PMID: 22937258; PMCID: PMC3420731.
    39. Singhal P, Rodriguez JN, Small W, Eagleston S, Van de Water J, Maitland DJ, Wilson TS. Ultra Low Density and Highly Crosslinked Biocompatible Shape Memory Polyurethane Foams. J Polym Sci B Polym Phys. 2012 May 15; 50(10):724-737. PMID: 22570509.
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    40. Goines PE, Croen LA, Braunschweig D, Yoshida CK, Grether J, Hansen R, Kharrazi M, Ashwood P, Van de Water J. Increased midgestational IFN-?, IL-4 and IL-5 in women bearing a child with autism: A case-control study. Mol Autism. 2011 Aug 02; 2:13. PMID: 21810230.
      View in: PubMed
    41. Ashwood P, Corbett BA, Kantor A, Schulman H, Van de Water J, Amaral DG. In search of cellular immunophenotypes in the blood of children with autism. PLoS One. 2011 May 04; 6(5):e19299. PMID: 21573236.
      View in: PubMed
    42. Wills S, Rossi CC, Bennett J, Martinez-Cerdeño V, Ashwood P, Amaral DG, Van de Water J. Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism. Mol Autism. 2011 Apr 26; 2:5. PMID: 21521495; PMCID: PMC3108923.
    43. Rossi CC, Van de Water J, Rogers SJ, Amaral DG. Detection of plasma autoantibodies to brain tissue in young children with and without autism spectrum disorders. Brain Behav Immun. 2011 Aug; 25(6):1123-35. PMID: 21420487; PMCID: PMC3313674.
    44. Goines P, Haapanen L, Boyce R, Duncanson P, Braunschweig D, Delwiche L, Hansen R, Hertz-Picciotto I, Ashwood P, Van de Water J. Autoantibodies to cerebellum in children with autism associate with behavior. Brain Behav Immun. 2011 Mar; 25(3):514-23. PMID: 21134442; PMCID: PMC3039058.
    45. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J Neuroimmunol. 2011 Mar; 232(1-2):196-9. PMID: 21095018; PMCID: PMC3053074.
    46. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain Behav Immun. 2011 Jul; 25(5):840-9. PMID: 20833247; PMCID: PMC3039713.
    47. Lleo A, Bowlus CL, Yang GX, Invernizzi P, Podda M, Van de Water J, Ansari AA, Coppel RL, Worman HJ, Gores GJ, Gershwin ME. Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis. Hepatology. 2010 Sep; 52(3):987-98. PMID: 20568301; PMCID: PMC2932809.
    48. Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav Immun. 2011 Jan; 25(1):40-5. PMID: 20705131; PMCID: PMC2991432.
    49. Careaga M, Van de Water J, Ashwood P. Immune dysfunction in autism: a pathway to treatment. Neurotherapeutics. 2010 Jul; 7(3):283-92. PMID: 20643381.
      View in: PubMed
    50. Goines P, Van de Water J. The immune system's role in the biology of autism. Curr Opin Neurol. 2010 Apr; 23(2):111-7. PMID: 20160651; PMCID: PMC2898160.
    51. Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotox Res. 2011 Jan; 19(1):31-48. PMID: 19937285.
      View in: PubMed
    52. Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotox Res. 2011 Jan; 19(1):1-13. PMID: 19921347; PMCID: PMC3006638.
    53. Wu YW, Croen LA, Torres AR, Van De Water J, Grether JK, Hsu NN. Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants. Ann Neurol. 2009 Nov; 66(5):663-70. PMID: 19938160.
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    54. McAllister AK, van de Water J. Breaking boundaries in neural-immune interactions. Neuron. 2009 Oct 15; 64(1):9-12. PMID: 19840540.
      View in: PubMed
    55. Onore C, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen R, Van de Water J, Ashwood P. Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders. J Neuroimmunol. 2009 Nov 30; 216(1-2):126-9. PMID: 19800697; PMCID: PMC2981175.
    56. Enstrom AM, Onore CE, Van de Water JA, Ashwood P. Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain Behav Immun. 2010 Jan; 24(1):64-71. PMID: 19666104; PMCID: PMC3014091.
    57. Enstrom AM, Van de Water JA, Ashwood P. Autoimmunity in autism. Curr Opin Investig Drugs. 2009 May; 10(5):463-73. PMID: 19431079.
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    58. Lleo A, Selmi C, Invernizzi P, Podda M, Coppel RL, Mackay IR, Gores GJ, Ansari AA, Van de Water J, Gershwin ME. Apotopes and the biliary specificity of primary biliary cirrhosis. Hepatology. 2009 Mar; 49(3):871-9. PMID: 19185000; PMCID: PMC2665925.
    59. Ashwood P, Schauer J, Pessah IN, Van de Water J. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. J Neuroimmunol. 2009 Mar 31; 208(1-2):130-5. PMID: 19211157; PMCID: PMC2692510.
    60. Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. Increased IgG4 levels in children with autism disorder. Brain Behav Immun. 2009 Mar; 23(3):389-95. PMID: 19136055; PMCID: PMC2696343.
    61. Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J Neuroimmunol. 2008 Nov 15; 204(1-2):149-53. PMID: 18762342; PMCID: PMC2615583.
    62. Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Res. 2008 Oct; 1(5):275-83. PMID: 19343198; PMCID: PMC2663897.
    63. Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain Behav Immun. 2009 Jan; 23(1):124-33. PMID: 18762240; PMCID: PMC2636576.
    64. Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water J. Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain Behav Immun. 2009 Jan; 23(1):64-74. PMID: 18706993; PMCID: PMC2660333.
    65. Croen LA, Braunschweig D, Haapanen L, Yoshida CK, Fireman B, Grether JK, Kharrazi M, Hansen RL, Ashwood P, Van de Water J. Maternal mid-pregnancy autoantibodies to fetal brain protein: the early markers for autism study. Biol Psychiatry. 2008 Oct 01; 64(7):583-8. PMID: 18571628.
      View in: PubMed
    66. Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Res. 2008 Jun; 1(3):169-78. PMID: 19132145.
      View in: PubMed
    67. Croen LA, Goines P, Braunschweig D, Yolken R, Yoshida CK, Grether JK, Fireman B, Kharrazi M, Hansen RL, Van de Water J. Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) Study. Autism Res. 2008 Apr; 1(2):130-7. PMID: 19119429.
      View in: PubMed
    68. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. PMID: 18394707; PMCID: PMC2475601.
    69. Martin LA, Ashwood P, Braunschweig D, Cabanlit M, Van de Water J, Amaral DG. Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism. Brain Behav Immun. 2008 Aug; 22(6):806-16. PMID: 18262386; PMCID: PMC3779644.
    70. Enstrom A, Onore C, Tarver A, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Peripheral Blood Leukocyte Production of BDNF following Mitogen Stimulation in Early Onset and Regressive Autism. Am J Biochem Biotechnol. 2008; 4(2):121-129. PMID: 27683277.
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    71. Enstrom A, Onore C, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Detection of IL-17 and IL-23 in Plasma Samples of Children with Autism. Am J Biochem Biotechnol. 2008; 4(2):114-120. PMID: 27688738.
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    72. Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: maternally derived antibodies specific for fetal brain proteins. Neurotoxicology. 2008 Mar; 29(2):226-31. PMID: 18078998; PMCID: PMC2305723.
    73. Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J. Autoantibodies in autism spectrum disorders (ASD). Ann N Y Acad Sci. 2007 Jun; 1107:79-91. PMID: 17804535.
      View in: PubMed
    74. Cabanlit M, Wills S, Goines P, Ashwood P, Van de Water J. Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder. Ann N Y Acad Sci. 2007 Jun; 1107:92-103. PMID: 17804536.
      View in: PubMed
    75. Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? J Autism Dev Disord. 2008 Jan; 38(1):169-75. PMID: 17347881.
      View in: PubMed
    76. Foreman AL, Van de Water J, Gougeon ML, Gershwin ME. B cells in autoimmune diseases: insights from analyses of immunoglobulin variable (Ig V) gene usage. Autoimmun Rev. 2007 Jun; 6(6):387-401. PMID: 17537385; PMCID: PMC2094701.
    77. Allina J, Hu B, Sullivan DM, Fiel MI, Thung SN, Bronk SF, Huebert RC, van de Water J, LaRusso NF, Gershwin ME, Gores GJ, Odin JA. T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis. J Autoimmun. 2006 Dec; 27(4):232-41. PMID: 17222534.
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    78. Cabanlit M, Maitland D, Wilson T, Simon S, Wun T, Gershwin ME, Van de Water J. Polyurethane shape-memory polymers demonstrate functional biocompatibility in vitro. Macromol Biosci. 2007 Jan 05; 7(1):48-55. PMID: 17238230.
      View in: PubMed
    79. Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect. 2006 Jul; 114(7):1119-25. PMID: 16835068; PMCID: PMC1513329.
    80. Ashwood P, Wills S, Van de Water J. The immune response in autism: a new frontier for autism research. J Leukoc Biol. 2006 Jul; 80(1):1-15. PMID: 16698940.
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    81. Croen LA, Grether JK, Yoshida CK, Odouli R, Van de Water J. Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: a case-control study. Arch Pediatr Adolesc Med. 2005 Feb; 159(2):151-7. PMID: 15699309.
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    82. Ashwood P, Van de Water J. Is autism an autoimmune disease? Autoimmun Rev. 2004 Nov; 3(7-8):557-62. PMID: 15546805.
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    83. Ashwood P, Van de Water J. A review of autism and the immune response. Clin Dev Immunol. 2004 Jun; 11(2):165-74. PMID: 15330453; PMCID: PMC2270714.
    84. Matsumura S, Van De Water J, Leung P, Odin JA, Yamamoto K, Gores GJ, Mostov K, Ansari AA, Coppel RL, Shiratori Y, Gershwin ME. Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis. Hepatology. 2004 May; 39(5):1415-22. PMID: 15122771.
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    85. Lawler CP, Croen LA, Grether JK, Van de Water J. Identifying environmental contributions to autism: provocative clues and false leads. Ment Retard Dev Disabil Res Rev. 2004; 10(4):292-302. PMID: 15666339.
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    86. Bruggraber SF, Leung PS, Amano K, Quan C, Kurth MJ, Nantz MH, Benson GD, Van de Water J, Luketic V, Roche TE, Ansari AA, Coppel RL, Gershwin ME. Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology. 2003 Dec; 125(6):1705-13. PMID: 14724823.
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    87. Selmi C, Balkwill DL, Invernizzi P, Ansari AA, Coppel RL, Podda M, Leung PS, Kenny TP, Van De Water J, Nantz MH, Kurth MJ, Gershwin ME. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology. 2003 Nov; 38(5):1250-7. PMID: 14578864.
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    88. Wu CT, Eiserich JP, Ansari AA, Coppel RL, Balasubramanian S, Bowlus CL, Gershwin ME, Van De Water J. Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions. Hepatology. 2003 Oct; 38(4):1018-25. PMID: 14512889.
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    89. Kita H, Ansari AA, He XS, Lian ZX, Van de Water J, Coppel RL, Luketic V, Kaplan M, Inamori H, Isoda N, Sugano K, Imawari M, Gershwin ME. Proteasome is required for class I-restricted presentation by Fcgamma receptor-mediated endocytosis in primary biliary cirrhosis. J Autoimmun. 2003 Sep; 21(2):175-82. PMID: 12935787.
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    90. Leung PS, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin ME. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. J Immunol. 2003 May 15; 170(10):5326-32. PMID: 12734383.
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    91. Fukushima N, Nalbandian G, Van De Water J, White K, Ansari AA, Leung P, Kenny T, Kamita SG, Hammock BD, Coppel RL, Stevenson F, Ishibashi H, Gershwin ME. Characterization of recombinant monoclonal IgA anti-PDC-E2 autoantibodies derived from patients with PBC. Hepatology. 2002 Dec; 36(6):1383-92. PMID: 12447863.
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    92. Mao TK, Kimura Y, Kenny TP, Branchi A, Gishi RG, Van de Water J, Kung HJ, Friedman SL, Gershwin ME. Elevated expression of tyrosine kinase DDR2 in primary biliary cirrhosis. Autoimmunity. 2002 Dec; 35(8):521-9. PMID: 12765478.
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    93. Matsumura S, Kita H, He XS, Ansari AA, Lian ZX, Van De Water J, Yamamoto K, Tsuji T, Coppel RL, Kaplan M, Gershwin ME. Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis. Hepatology. 2002 Nov; 36(5):1125-34. PMID: 12395322.
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    94. Kimura Y, Leung PS, Kenny TP, Van De Water J, Nishioka M, Giraud AS, Neuberger J, Benson G, Kaul R, Ansari AA, Coppel RL, Gershwin ME. Differential expression of intestinal trefoil factor in biliary epithelial cells of primary biliary cirrhosis. Hepatology. 2002 Nov; 36(5):1227-35. PMID: 12395334.
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    95. Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, Coppel RL, Kaplan MM, Gershwin ME. Analysis of TCR antagonism and molecular mimicry of an HLA-A0201-restricted CTL epitope in primary biliary cirrhosis. Hepatology. 2002 Oct; 36(4 Pt 1):918-26. PMID: 12297839.
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    96. Kita H, Naidenko OV, Kronenberg M, Ansari AA, Rogers P, He XS, Koning F, Mikayama T, Van De Water J, Coppel RL, Kaplan M, Gershwin ME. Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer. Gastroenterology. 2002 Oct; 123(4):1031-43. PMID: 12360465.
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    97. Suzuki A, Van de Water J, Gershwin ME, Jorgensen R, Angulo P, Lindor K. Oral tolerance and pyruvate dehydrogenase in patients with primary biliary cirrhosis. Dev Immunol. 2002 Jun; 9(2):55-61. PMID: 12739782; PMCID: PMC2276096.
    98. Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, Coppel RL, Kaplan MM, Gershwin ME. Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis. J Clin Invest. 2002 May; 109(9):1231-40. PMID: 11994412; PMCID: PMC150963.
    99. Sasaki M, Long SA, Van De Water J, He XS, Shultz L, Coppel RL, Ansari A, Nakanuma Y, Gershwin ME. The SJL/J mouse is not a model for PBC. Hepatology. 2002 May; 35(5):1284-6. PMID: 11981783.
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    100. Korvatska E, Van de Water J, Anders TF, Gershwin ME. Genetic and immunologic considerations in autism. Neurobiol Dis. 2002 Mar; 9(2):107-25. PMID: 11895365.
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    101. Long SA, Van de Water J, Gershwin ME. Antimitochondrial antibodies in primary biliary cirrhosis: the role of xenobiotics. Autoimmun Rev. 2002 Feb; 1(1-2):37-42. PMID: 12849056.
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    102. Kita H, Lian ZX, Van de Water J, He XS, Matsumura S, Kaplan M, Luketic V, Coppel RL, Ansari AA, Gershwin ME. Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells. J Exp Med. 2002 Jan 07; 195(1):113-23. PMID: 11781370; PMCID: PMC2196012.
    103. Matsumura S, Van De Water J, Kita H, Coppel RL, Tsuji T, Yamamoto K, Ansari AA, Gershwin ME. Contribution to antimitochondrial antibody production: cleavage of pyruvate dehydrogenase complex-E2 by apoptosis-related proteases. Hepatology. 2002 Jan; 35(1):14-22. PMID: 11786955.
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    104. Mao TK, Van De Water J, Keen CL, Osburn BO, Silva JS, Gershwin ME. Effects of a Combination of Traditional Chinese Botanicals (Immune+) on the Secretion of Interleukin-1beta and Interferon-gamma by Peripheral Blood Mononuclear Cells. J Med Food. 2001; 4(1):1-7. PMID: 12639282.
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