Weici Zhang

Title(s)Associate Adjunct Professor, MED: Int Med Rheumatology
SchoolSchool of Medicine
Address451 Health Sciences Drive, Genome Biomedical Sci Fac Suite 6510
CA 95616
Phone530-752-3285
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    1. IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury. Liver Int. 2026 Mar; 46(3):e70525. Zhou X, Shao S, Yang D, Cheng Z, Tanaka T, Leung PSC, Tsuneyama K, Ansari AA, Ridgway WM, Invernizzi P, Bowlus CL, Gershwin ME, Zhang W. PMID: 41603281; PMCID: PMC12848849.
      View in: PubMed   Mentions:
    2. Alternate splicing converts human CD137 from costimulatory to immunosuppressive function. J Autoimmun. 2025 Dec; 157:103498. Rojas M, Heuer LS, Zhang W, Sweeney N, Ramírez-Santana C, Leung PSC, Lam A, Kamat S, Mendelsohn AR, Huang M, Yu B, Ackerman P, Wei Q, Larrick JW, Chen YG, Ridgway WM. PMID: 41205341.
      View in: PubMed   Mentions:
    3. Higher order receptor clustering due to the IgG3 subclass is necessary for TLR4 signaling and tolerance induction by novel human anti-TLR4 antibodies. MAbs. 2025 Dec; 17(1):2515415. Heuer LS, Sweeney N, Rojas M, Zhang W, Mendelsohn AR, Huang M, Yu B, Ackerman P, Wei Q, Herr AB, Larrick JW, Ridgway WM. PMID: 40464120; PMCID: PMC12143713.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Immunobiology of bile and cholangiocytes. J Autoimmun. 2025 Feb; 151:103376. Li Y, Leung PS, Zhang W, Zhang S, Liu Z, Kurth M, Patterson AD, Gershwin ME, Song J. PMID: 39892203.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. PD-1+CD8+ T Cell-Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease. Adv Sci (Weinh). 2025 Jan; 12(1):e2407284. Long J, Yang SY, Bian ZH, Zhu HX, Ma M, Wang XQ, Li L, Zhang W, Han Y, Gershwin ME, Lian ZX, Zhao ZB. PMID: 39494472; PMCID: PMC11714232.
      View in: PubMed   Mentions:
    6. Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale. Liver Int. 2024 Oct; 44(10):2834-2846. Zhang W, Al Tekreeti T, Leung PSC, Tsuneyama K, Dhillon H, Rojas M, Heuer LS, Ridgway WM, Ansari AA, Young HA, Mackay CR, Gershwin ME. PMID: 39101371; PMCID: PMC11464203.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Ninjurin 2 Modulates Tumorigenesis, Inflammation, and Metabolism via Pyroptosis. Am J Pathol. 2024 05; 194(5):849-860. Zhang J, Kong X, Yang HJ, Zhang W, Chen M, Chen X. PMID: 38325550; PMCID: PMC11074982.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    8. Dual B-cell targeting therapy ameliorates autoimmune cholangitis. J Autoimmun. 2022 10; 132:102897. Zhang W, Shao T, Leung PSC, Tsuneyama K, Heuer L, Young HA, Ridgway WM, Gershwin ME. PMID: 36029718; PMCID: PMC10311358.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    9. The myristoylated alanine-rich C-kinase substrates (MARCKS): A membrane-anchored mediator of the cell function. Autoimmun Rev. 2021 Nov; 20(11):102942. Chen Z, Zhang W, Selmi C, Ridgway WM, Leung PSC, Zhang F, Gershwin ME. PMID: 34509657; PMCID: PMC9746065.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    10. Antibody glycosylation in autoimmune diseases. Autoimmun Rev. 2021 May; 20(5):102804. Zhou X, Motta F, Selmi C, Ridgway WM, Gershwin ME, Zhang W. PMID: 33727152; PMCID: PMC8058319.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    11. Interleukin-35 Promotes Th9 Cell Differentiation in IgG4-Related Disorders: Experimental Data and Review of the Literature. Clin Rev Allergy Immunol. 2021 Feb; 60(1):132-145. Zhang J, Lian M, Li B, Gao L, Tanaka T, You Z, Wei Y, Chen Y, Li Y, Li Y, Huang B, Tang R, Wang Q, Miao Q, Peng Y, Fang J, Lian Z, Okazaki K, Xiao X, Zhang W, Ma X. PMID: 32712804.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    12. Glycomic analysis of antibody indicates distinctive glycosylation profile in patients with autoimmune cholangitis. J Autoimmun. 2020 09; 113:102503. Zhou X, Kailemia MJ, Sun Y, Shuai Z, Yang GX, Dhaliwal S, Cristoferi L, Leung PSC, Invernizzi P, Bowlus CL, Lebrilla CB, Ansari AA, Ridgway WM, Zhang W, Gershwin ME. PMID: 32546343.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    13. Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis. Clin Rev Allergy Immunol. 2020 Feb; 58(1):25-38. Chen W, Wei Y, Xiong A, Li Y, Guan H, Wang Q, Miao Q, Bian Z, Xiao X, Lian M, Zhang J, Li B, Cao Q, Fan Z, Zhang W, Qiu D, Fang J, Gershwin ME, Yang L, Tang R, Ma X. PMID: 30900136.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    14. Exosomal microRNA in autoimmunity. Cell Mol Immunol. 2019 12; 16(12):932-934. Duan W, Zhang W, Jia J, Lu Q, Eric Gershwin M. PMID: 31664221; PMCID: PMC6884449.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    15. Liver-resident NK cells suppress autoimmune cholangitis and limit the proliferation of CD4+ T cells. Cell Mol Immunol. 2020 02; 17(2):178-189. Zhao ZB, Lu FT, Ma HD, Wang YH, Yang W, Long J, Miao Q, Zhang W, Tian Z, Ridgway WM, Cao J, Gershwin ME, Lian ZX. PMID: 30874628; PMCID: PMC7000693.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    16. Common Variable Immunodeficiency and Liver Involvement. Clin Rev Allergy Immunol. 2018 Dec; 55(3):340-351. Song J, Lleo A, Yang GX, Zhang W, Bowlus CL, Gershwin ME, Leung PSC. PMID: 28785926; PMCID: PMC5803456.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    17. Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice. Front Immunol. 2018; 9:2534. Moritoki Y, Tsuneyama K, Nakamura Y, Kikuchi K, Shiota A, Ohsugi Y, Lian ZX, Zhang W, Yang GX, Ueki S, Takeda M, Omokawa A, Saga T, Saga A, Watanabe D, Miura M, Ueno Y, Leung PSC, Tanaka A, Gershwin ME, Hirokawa M. PMID: 30450101; PMCID: PMC6224429.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    18. Gut microbiota translocation promotes autoimmune cholangitis. J Autoimmun. 2018 12; 95:47-57. Ma HD, Zhao ZB, Ma WT, Liu QZ, Gao CY, Li L, Wang J, Tsuneyama K, Liu B, Zhang W, Zhou Y, Gershwin ME, Lian ZX. PMID: 30340822; PMCID: PMC6290354.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    19. The Immunobiology of Receptor Activator for Nuclear Factor Kappa B Ligand and Myeloid-Derived Suppressor Cell Activation in Immunoglobulin G4-Related Sclerosing Cholangitis. Hepatology. 2018 11; 68(5):1922-1936. Lian M, Wang Q, Jiang X, Zhang J, Wei Y, Li Y, Li B, Chen W, Zhang H, Miao Q, Peng Y, Xiao X, Sheng L, Zhang W, Fang J, Tang R, Gershwin ME, Ma X. PMID: 29774578.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. The Immunologic Paradoxes of IgG4-Related Disease. Clin Rev Allergy Immunol. 2018 Apr; 54(2):344-351. Xiao X, Lian M, Zhang W, Eric Gershwin M, Ma X. PMID: 29460058.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    21. The immunobiology of mucosal-associated invariant T cell (MAIT) function in primary biliary cholangitis: Regulation by cholic acid-induced Interleukin-7. J Autoimmun. 2018 06; 90:64-75. Jiang X, Lian M, Li Y, Zhang W, Wang Q, Wei Y, Zhang J, Chen W, Xiao X, Miao Q, Bian Z, Qiu D, Fang J, Ansari AA, Leung PSC, Coppel RL, Tang R, Gershwin ME, Ma X. PMID: 29429758.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    22. Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis. Cell Mol Immunol. 2018 08; 15(8):756-767. Zhang W, Zhang R, Zhang J, Sun Y, Leung PS, Yang GX, Shuai Z, Ridgway WM, Gershwin ME. PMID: 29375127; PMCID: PMC6141482.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    23. Genetic Ablation of Rbm38 Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. Cancer Res. 2018 03 15; 78(6):1511-1521. Zhang J, Xu E, Ren C, Yang HJ, Zhang Y, Sun W, Kong X, Zhang W, Chen M, Huang E, Chen X. PMID: 29330147; PMCID: PMC6340497.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    24. The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1). Autoimmun Rev. 2018 Jan; 17(1):78-85. Guo CJ, Leung PSC, Zhang W, Ma X, Gershwin ME. PMID: 29108822.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    25. Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11500-11505. Yang HJ, Zhang J, Yan W, Cho SJ, Lucchesi C, Chen M, Huang EC, Scoumanne A, Zhang W, Chen X. PMID: 29073078; PMCID: PMC5664541.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    26. Autoreactive monoclonal antibodies from patients with primary biliary cholangitis recognize environmental xenobiotics. Hepatology. 2017 09; 66(3):885-895. Tanaka T, Zhang W, Sun Y, Shuai Z, Chida AS, Kenny TP, Yang GX, Sanz I, Ansari A, Bowlus CL, Ippolito GC, Coppel RL, Okazaki K, He XS, Leung PSC, Gershwin ME. PMID: 28470667; PMCID: PMC5570636.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. Long noncoding RNA lncKdm2b: A critical player in the maintenance of group 3 innate lymphoid cells. Cell Mol Immunol. 2018 01; 15(1):5-7. Guo CJ, Zhang W, Gershwin ME. PMID: 28690327; PMCID: PMC5827179.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    28. The fingerprint of antimitochondrial antibodies and the etiology of primary biliary cholangitis. Hepatology. 2017 05; 65(5):1670-1682. Shuai Z, Wang J, Badamagunta M, Choi J, Yang G, Zhang W, Kenny TP, Guggenheim K, Kurth MJ, Ansari AA, Voss J, Coppel RL, Invernizzi P, Leung PSC, Gershwin ME. PMID: 28100006; PMCID: PMC5397331.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    29. Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3. Phytomedicine. 2016 Nov 15; 23(12):1329-1336. Zhang G, Zeng X, Zhang R, Liu J, Zhang W, Zhao Y, Zhang X, Wu Z, Tan Y, Wu Y, Du B. PMID: 27765352.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    30. Endogenous interleukin-22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice. Clin Exp Immunol. 2016 08; 185(2):154-64. Yang GX, Sun Y, Tsuneyama K, Zhang W, Leung PS, He XS, Ansari AA, Bowlus C, Ridgway WM, Gershwin ME. PMID: 27148790; PMCID: PMC4955007.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    31. Autotaxin, Pruritus and Primary Biliary Cholangitis (PBC). Autoimmun Rev. 2016 Aug; 15(8):795-800. Sun Y, Zhang W, Evans JF, Floreani A, Zou Z, Nishio Y, Qi R, Leung PS, Bowlus CL, Gershwin ME. PMID: 27019050.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    32. Adaptive immunity in the liver. Cell Mol Immunol. 2016 05; 13(3):354-68. Shuai Z, Leung MW, He X, Zhang W, Yang G, Leung PS, Eric Gershwin M. PMID: 26996069; PMCID: PMC4856810.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    33. The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis. Cell Mol Immunol. 2017 Mar; 14(3):276-284. Tomiyama T, Yang GX, Zhao M, Zhang W, Tanaka H, Wang J, Leung PS, Okazaki K, He XS, Lu Q, Coppel RL, Bowlus CL, Gershwin ME. PMID: 26388238; PMCID: PMC5360882.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    34. DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis. Clin Epigenetics. 2015; 7:61. Lleo A, Zhang W, Zhao M, Tan Y, Bernuzzi F, Zhu B, Liu Q, Tan Q, Malinverno F, Valenti L, Jiang T, Tan L, Liao W, Coppel R, Invernizzi P, Lu Q, Adams DH, Gershwin ME, PBC Epigenetic Study Group. PMID: 26150899; PMCID: PMC4491885.
      View in: PubMed   Mentions: 38     Fields:    
    35. The coexistence of Sjögren's syndrome and primary biliary cirrhosis: a comprehensive review. Clin Rev Allergy Immunol. 2015 Jun; 48(2-3):301-15. Sun Y, Zhang W, Li B, Zou Z, Selmi C, Gershwin ME. PMID: 25682089.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    36. Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis. Clin Exp Immunol. 2015 Jun; 180(3):371-82. Tanaka H, Yang GX, Tomiyama T, Tsuneyama K, Zhang W, Leung PS, Coppel RL, Joh T, Nadler SG, Ansari AA, Bowlus C, Gershwin ME. PMID: 25581259; PMCID: PMC4449766.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    37. Women and primary biliary cirrhosis. Clin Rev Allergy Immunol. 2015 Jun; 48(2-3):285-300. Sun Y, Haapanen K, Li B, Zhang W, Van de Water J, Gershwin ME. PMID: 25241227; PMCID: PMC9719371.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    38. Innate immunity drives the initiation of a murine model of primary biliary cirrhosis. PLoS One. 2015; 10(3):e0121320. Chang CH, Chen YC, Zhang W, Leung PS, Gershwin ME, Chuang YH. PMID: 25807531; PMCID: PMC4373957.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    39. Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells. Clin Exp Immunol. 2014 Nov; 178(2):253-61. Tanaka H, Zhang W, Yang GX, Ando Y, Tomiyama T, Tsuneyama K, Leung P, Coppel RL, Ansari AA, Lian ZX, Ridgway WM, Joh T, Gershwin ME. PMID: 25041369; PMCID: PMC4233375.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    40. Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis. Hepatology. 2014 Nov; 60(5):1708-16. Zhang J, Zhang W, Leung PS, Bowlus CL, Dhaliwal S, Coppel RL, Ansari AA, Yang GX, Wang J, Kenny TP, He XS, Mackay IR, Gershwin ME. PMID: 25043065; PMCID: PMC4211937.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    41. Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells. Hepatology. 2014 Oct; 60(4):1314-23. Lleo A, Zhang W, McDonald WH, Seeley EH, Leung PS, Coppel RL, Ansari AA, Adams DH, Afford S, Invernizzi P, Gershwin ME. PMID: 24841946; PMCID: PMC4175017.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    42. Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα(-/-) mice. J Autoimmun. 2014 Jun; 51:99-108. Yao Y, Yang W, Yang YQ, Ma HD, Lu FT, Li L, Tao YY, Tsuneyama K, Zhang W, Friedman S, Gershwin ME, Lian ZX. PMID: 24651036.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    43. Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. J Autoimmun. 2014 May; 50:123-34. Huang W, Kachapati K, Adams D, Wu Y, Leung PS, Yang GX, Zhang W, Ansari AA, Flavell RA, Gershwin ME, Ridgway WM. PMID: 24556277; PMCID: PMC4098881.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    44. Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD).B6 (Idd10/Idd18) mice. Clin Exp Immunol. 2014 Feb; 175(2):192-201. Wang JJ, Yang GX, Zhang WC, Lu L, Tsuneyama K, Kronenberg M, Véla JL, Lopez-Hoyos M, He XS, Ridgway WM, Leung PS, Gershwin ME. PMID: 24128311; PMCID: PMC3892410.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    45. Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis. PLoS One. 2013; 8(9):e74225. Kawata K, Tsuda M, Yang GX, Zhang W, Tanaka H, Tsuneyama K, Leung P, He XS, Knechtle S, Ansari AA, Coppel RL, Gershwin ME. PMID: 24040208; PMCID: PMC3769355.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    46. Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice. Hepatology. 2013 Sep; 58(3):1094-104. Kawata K, Yang GX, Ando Y, Tanaka H, Zhang W, Kobayashi Y, Tsuneyama K, Leung PS, Lian ZX, Ridgway WM, Ansari AA, He XS, Gershwin ME. PMID: 23532950; PMCID: PMC3716874.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    47. Human intrahepatic biliary epithelial cells engulf blebs from their apoptotic peers. Clin Exp Immunol. 2013 Apr; 172(1):95-103. Rong GH, Yang GX, Ando Y, Zhang W, He XS, Leung PS, Coppel RL, Ansari AA, Zhong R, Gershwin ME. PMID: 23480189; PMCID: PMC3719935.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    48. Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse. J Autoimmun. 2013 Mar; 41:111-9. Ando Y, Yang GX, Kenny TP, Kawata K, Zhang W, Huang W, Leung PS, Lian ZX, Okazaki K, Ansari AA, He XS, Invernizzi P, Ridgway WM, Lu Q, Gershwin ME. PMID: 23395552; PMCID: PMC3622842.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    49. Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology. 2013 Feb; 57(2):708-15. Dhirapong A, Yang GX, Nadler S, Zhang W, Tsuneyama K, Leung P, Knechtle S, Ansari AA, Coppel RL, Liu FT, He XS, Gershwin ME. PMID: 22996325; PMCID: PMC3548049.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    50. Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice. Hepatology. 2013 Feb; 57(2):806-16. Tsuda M, Zhang W, Yang GX, Tsuneyama K, Ando Y, Kawata K, Park O, Leung PS, Coppel RL, Ansari AA, Ridgway WM, Gao B, Lian ZX, Flavell R, He XS, Gershwin ME. PMID: 22576253; PMCID: PMC3424295.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    51. Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβ receptor II. PLoS One. 2012; 7(11):e49413. Zhang W, Tsuda M, Yang GX, Tsuneyama K, He XS, Ansari AA, Ridgway WM, Coppel RL, Lian ZX, Leung PS, Gershwin ME. PMID: 23145171; PMCID: PMC3492285.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    52. The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice. Hepatology. 2012 Oct; 56(4):1418-26. Ando Y, Yang GX, Tsuda M, Kawata K, Zhang W, Nakajima T, Tsuneyama K, Leung P, Lian ZX, Okazaki K, Ridgway WM, Norman GL, Ansari AA, He XS, Coppel RL, Gershwin ME. PMID: 22532156; PMCID: PMC3415593.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    53. Mincle and human B cell function. J Autoimmun. 2012 12; 39(4):315-22. Kawata K, Illarionov P, Yang GX, Kenny TP, Zhang W, Tsuda M, Ando Y, Leung PS, Ansari AA, Gershwin ME. PMID: 22698596; PMCID: PMC3443704.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    54. Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent. Clin Exp Immunol. 2012 Jun; 168(3):261-7. Yang CY, Leung PS, Yang GX, Kenny TP, Zhang W, Coppel R, Norman GL, Ansari AA, Mackay IR, Worman HJ, Gershwin ME. PMID: 22519587; PMCID: PMC3390476.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    55. Biochemical and immunologic effects of rituximab in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid. Hepatology. 2012 Feb; 55(2):512-21. Tsuda M, Moritoki Y, Lian ZX, Zhang W, Yoshida K, Wakabayashi K, Yang GX, Nakatani T, Vierling J, Lindor K, Gershwin ME, Bowlus CL. PMID: 22006563; PMCID: PMC12168494.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCellsCTClinical Trials
    56. Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis. Hepatology. 2011 Oct; 54(4):1293-302. Tsuda M, Ambrosini YM, Zhang W, Yang GX, Ando Y, Rong G, Tsuneyama K, Sumida K, Shimoda S, Bowlus CL, Leung PS, He XS, Coppel RL, Ansari AA, Lian ZX, Gershwin ME. PMID: 21735469; PMCID: PMC3184190.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    57. The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis. Clin Exp Immunol. 2011 Oct; 166(1):110-20. Ambrosini YM, Yang GX, Zhang W, Tsuda M, Shu S, Tsuneyama K, Leung PS, Ansari AA, Coppel RL, Gershwin ME. PMID: 21910728; PMCID: PMC3193926.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    58. T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1. J Autoimmun. 2011 Sep; 37(2):71-8. Zhang W, Ono Y, Miyamura Y, Bowlus CL, Gershwin ME, Maverakis E. PMID: 21636249; PMCID: PMC4018194.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    59. B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis. Cell Immunol. 2011; 268(1):16-23. Moritoki Y, Tsuda M, Tsuneyama K, Zhang W, Yoshida K, Lian ZX, Yang GX, Ridgway WM, Wicker LS, Ansari AA, Gershwin ME. PMID: 21349500; PMCID: PMC3056928.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    60. Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitis. Hepatology. 2010 Jul; 52(1):215-22. Zhang W, Tsuda M, Yang GX, Tsuneyama K, Rong G, Ridgway WM, Ansari AA, Flavell RA, Coppel RL, Lian ZX, Gershwin ME. PMID: 20578264; PMCID: PMC2936774.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    61. B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice. Hepatology. 2009 Dec; 50(6):1893-903. Moritoki Y, Lian ZX, Lindor K, Tuscano J, Tsuneyama K, Zhang W, Ueno Y, Dunn R, Kehry M, Coppel RL, Mackay IR, Gershwin ME. PMID: 19877182; PMCID: PMC4130556.
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    62. Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice. Hepatology. 2009 Nov; 50(5):1494-500. Yoshida K, Yang GX, Zhang W, Tsuda M, Tsuneyama K, Moritoki Y, Ansari AA, Okazaki K, Lian ZX, Coppel RL, Mackay IR, Gershwin ME. PMID: 19676134; PMCID: PMC2783300.
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    64. Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production. Gastroenterology. 2009 Dec; 137(6):2125-35.e1-2. Lafdil F, Wang H, Park O, Zhang W, Moritoki Y, Yin S, Fu XY, Gershwin ME, Lian ZX, Gao B. PMID: 19686746; PMCID: PMC2789897.
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    65. E2F1 Induces tumor cell survival via nuclear factor-kappaB-dependent induction of EGR1 transcription in prostate cancer cells. Cancer Res. 2009 Mar 15; 69(6):2324-31. Zheng C, Ren Z, Wang H, Zhang W, Kalvakolanu DV, Tian Z, Xiao W. PMID: 19276347.
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    66. Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis. Hepatology. 2009 Feb; 49(2):545-52. Zhang W, Sharma R, Ju ST, He XS, Tao Y, Tsuneyama K, Tian Z, Lian ZX, Fu SM, Gershwin ME. PMID: 19065675; PMCID: PMC2635418.
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    68. B cells suppress the inflammatory response in a mouse model of primary biliary cirrhosis. Gastroenterology. 2009 Mar; 136(3):1037-47. Moritoki Y, Zhang W, Tsuneyama K, Yoshida K, Wakabayashi K, Yang GX, Bowlus C, Ridgway WM, Ueno Y, Ansari AA, Coppel RL, Mackay IR, Flavell RA, Gershwin ME, Lian ZX. PMID: 19118554.
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    69. Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts. Clin Cancer Res. 2008 Oct 15; 14(20):6432-9. Zhang W, Chen Y, Wei H, Zheng C, Sun R, Zhang J, Tian Z. PMID: 18927282.
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    70. mRNA secondary structure at start AUG codon is a key limiting factor for human protein expression in Escherichia coli. Biochem Biophys Res Commun. 2006 Oct 13; 349(1):69-78. Zhang W, Xiao W, Wei H, Zhang J, Tian Z. PMID: 16930549.
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    71. TLR3 ligand-induced accumulation of activated splenic natural killer cells into liver. Cell Mol Immunol. 2005 Dec; 2(6):449-53. Wang J, Xu J, Zhang W, Wei H, Tian Z. PMID: 16426495.
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    72. Recombinant human prolactin protects against irradiation-induced myelosuppression. Cell Mol Immunol. 2005 Oct; 2(5):379-85. Zhang WC, Sun R, Zhang J, Zhang J, Tian Z. PMID: 16368065.
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    73. Recombinant human prolactin improves antitumor effects of murine natural killer cells in vitro and in vivo. Neuroimmunomodulation. 2002-2003; 10(3):169-76. Sun R, Wei H, Zhang J, Li A, Zhang W, Tian Z. PMID: 12481157.
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