Scott I Simon

Title(s)Professor, Biomedical Engineering
SchoolUniversity of California, Davis
Address3313 GBSF
CA 95616
Phone530-752-0299
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes. Cell Host Microbe. 2022 06 08; 30(6):836-847.e6. Liou MJ, Miller BM, Litvak Y, Nguyen H, Natwick DE, Savage HP, Rixon JA, Mahan SP, Hiyoshi H, Rogers AWL, Velazquez EM, Butler BP, Collins SR, McSorley SJ, Harshey RM, Byndloss MX, Simon SI, Bäumler AJ. PMID: 35568027; PMCID: PMC9187619.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation. Cardiovasc Res. 2022 03 25; 118(5):1289-1302. Immler R, Nadolni W, Bertsch A, Morikis V, Rohwedder I, Masgrau-Alsina S, Schroll T, Yevtushenko A, Soehnlein O, Moser M, Gudermann T, Barnea ER, Rehberg M, Simon SI, Zierler S, Pruenster M, Sperandio M. PMID: 33881519; PMCID: PMC8953450.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    3. Targeting Neutrophil Adhesive Events to Address Vaso-Occlusive Crisis in Sickle Cell Patients. Front Immunol. 2021; 12:663886. Morikis VA, Hernandez AA, Magnani JL, Sperandio M, Simon SI. PMID: 33995392; PMCID: PMC8113856.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Evading the host response: Staphylococcus "hiding" in cortical bone canalicular system causes increased bacterial burden. Bone Res. 2020 Dec 10; 8(1):43. Zoller SD, Hegde V, Burke ZDC, Park HY, Ishmael CR, Blumstein GW, Sheppard W, Hamad C, Loftin AH, Johansen DO, Smith RA, Sprague MM, Hori KR, Clarkson SJ, Borthwell R, Simon SI, Miller JF, Nelson SD, Bernthal NM. PMID: 33303744; PMCID: PMC7728749.
      View in: PubMed   Mentions: 8  
    5. Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics. Front Immunol. 2020; 11:571489. Garcia G, Kim MH, Morikis VA, Simon SI. PMID: 33362760; PMCID: PMC7757401.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. J Immunol. 2020 11 15; 205(10):2806-2820. Hernandez AA, Foster GA, Soderberg SR, Fernandez A, Reynolds MB, Orser MK, Bailey KA, Rogers JH, Singh GD, Wu H, Passerini AG, Simon SI. PMID: 33055281; PMCID: PMC7653512.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. The 2020 Young Innovators of Cellular and Molecular Bioengineering. Cell Mol Bioeng. 2020 Oct; 13(5):391-392. King MR, Peyton S, Simon SI. PMID: 33184572; PMCID: PMC7596122.
      View in: PubMed   Mentions:
    8. Tensile force transmitted through LFA-1 bonds mechanoregulate neutrophil inflammatory response. J Leukoc Biol. 2020 12; 108(6):1815-1828. Morikis VA, Masadeh E, Simon SI. PMID: 32531836.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. IRF-1 mediates the suppressive effects of mTOR inhibition on arterial endothelium. J Mol Cell Cardiol. 2020 03; 140:30-41. Peng K, Fan X, Li Q, Wang Y, Chen X, Xiao P, Passerini AG, Simon SI, Sun C. PMID: 32087218; PMCID: PMC7138750.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    10. Preclinical Models and Methodologies for Monitoring Staphylococcus aureus Infections Using Noninvasive Optical Imaging. Methods Mol Biol. 2020; 2069:197-228. Archer NK, Wang Y, Ortines RV, Liu H, Nolan SJ, Liu Q, Alphonse MP, Dikeman DA, Mazhar M, Miller RJ, Anderson LS, Francis KP, Simon SI, Miller LS. PMID: 31523776; PMCID: PMC7745539.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    11. Kinky integrins reveal a new wrinkle in neutrophil activation. J Leukoc Biol. 2020 02; 107(2):167-169. Morikis VA, Rivara K, Simon SI. PMID: 31777979.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    12. Development of a computational model for acute ischemic stroke recanalization through cyclic aspiration. Biomech Model Mechanobiol. 2020 Apr; 19(2):761-778. Good BC, Simon S, Manning K, Costanzo F. PMID: 31686306.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Replacing Saturated Fat With Unsaturated Fat in Western Diet Reduces Foamy Monocytes and Atherosclerosis in Male Ldlr-/- Mice. Arterioscler Thromb Vasc Biol. 2020 01; 40(1):72-85. Lian Z, Perrard XD, Peng X, Raya JL, Hernandez AA, Johnson CG, Lagor WR, Pownall HJ, Hoogeveen RC, Simon SI, Sacks FM, Ballantyne CM, Wu H. PMID: 31619061; PMCID: PMC6991890.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    14. Mechanoregulation of p38 activity enhances endoplasmic reticulum stress-mediated inflammation by arterial endothelium. FASEB J. 2019 11; 33(11):12888-12899. Bailey KA, Moreno E, Haj FG, Simon SI, Passerini AG. PMID: 31499005; PMCID: PMC6902662.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    15. Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal. Sci Rep. 2019 06 17; 9(1):8655. Rajamani A, Borkowski K, Akre S, Fernandez A, Newman JW, Simon SI, Passerini AG. PMID: 31209255; PMCID: PMC6572825.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Clonal Vγ6+Vδ4+ T cells promote IL-17-mediated immunity against Staphylococcus aureus skin infection. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10917-10926. Marchitto MC, Dillen CA, Liu H, Miller RJ, Archer NK, Ortines RV, Alphonse MP, Marusina AI, Merleev AA, Wang Y, Pinsker BL, Byrd AS, Brown ID, Ravipati A, Zhang E, Cai SS, Limjunyawong N, Dong X, Yeaman MR, Simon SI, Shen W, Durum SK, O'Brien RL, Maverakis E, Miller LS. PMID: 31088972; PMCID: PMC6561199.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    17. CCR6+ γδ T Cells Home to Skin Wounds and Restore Normal Wound Healing in CCR6-Deficient Mice. J Invest Dermatol. 2019 09; 139(9):2061-2064.e2. Anderson LS, Yu S, Rivara KR, Reynolds MB, Hernandez AA, Wu X, Yang HY, Isseroff RR, Miller LS, Hwang ST, Simon SI. PMID: 30935975; PMCID: PMC6708754.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    18. A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection. J Vis Exp. 2019 02 28; (144). Anderson LS, Reynolds MB, Rivara KR, Miller LS, Simon SI. PMID: 30882782; PMCID: PMC6605055.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    19. Neutrophil Mechanosignaling Promotes Integrin Engagement With Endothelial Cells and Motility Within Inflamed Vessels. Front Immunol. 2018; 9:2774. Morikis VA, Simon SI. PMID: 30546362; PMCID: PMC6279920.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    20. Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF-α-induced VCAM-1 expression and monocytic cell adhesion. Am J Physiol Heart Circ Physiol. 2019 02 01; 316(2):H408-H420. Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C. PMID: 30462552; PMCID: PMC6397389.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    21. Selectin-Targeting Peptide-Glycosaminoglycan Conjugates Modulate Neutrophil-Endothelial Interactions. Cell Mol Bioeng. 2019; 12(1):121-130. Wodicka JR, Morikis VA, Dehghani T, Simon SI, Panitch A. PMID: 30740185; PMCID: PMC6345733.
      View in: PubMed   Mentions: 4  
    22. Is CCR6 Required for the Development of Psoriasiform Dermatitis in Mice? J Invest Dermatol. 2019 02; 139(2):485-488. Yu S, Wu X, Zhou Y, Han D, Anderson LS, Simon SI, Hwang ST, Imai Y. PMID: 30193756; PMCID: PMC6613549.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. Calcium signalling and related ion channels in neutrophil recruitment and function. Eur J Clin Invest. 2018 Nov; 48 Suppl 2:e12964. Immler R, Simon SI, Sperandio M. PMID: 29873837; PMCID: PMC6221920.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    24. CagY-Dependent Regulation of Type IV Secretion in Helicobacter pylori Is Associated with Alterations in Integrin Binding. mBio. 2018 05 15; 9(3). Skoog EC, Morikis VA, Martin ME, Foster GA, Cai LP, Hansen LM, Li B, Gaddy JA, Simon SI, Solnick JV. PMID: 29764950; PMCID: PMC5954226.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    25. Neutrophils in hot pursuit of MRSA in the lymph nodes. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):2272-2274. Miller LS, Simon SI. PMID: 29476009; PMCID: PMC5877973.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. J Clin Invest. 2018 03 01; 128(3):1026-1042. Dillen CA, Pinsker BL, Marusina AI, Merleev AA, Farber ON, Liu H, Archer NK, Lee DB, Wang Y, Ortines RV, Lee SK, Marchitto MC, Cai SS, Ashbaugh AG, May LS, Holland SM, Freeman AF, Miller LG, Yeaman MR, Simon SI, Milner JD, Maverakis E, Miller LS. PMID: 29400698; PMCID: PMC5824877.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    27. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. Blood. 2017 11 09; 130(19):2101-2110. Morikis VA, Chase S, Wun T, Chaikof EL, Magnani JL, Simon SI. PMID: 28811304; PMCID: PMC5680610.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCellsCTClinical Trials
    28. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. Sci Rep. 2017 08 15; 7(1):8196. Bailey KA, Haj FG, Simon SI, Passerini AG. PMID: 28811527; PMCID: PMC5557756.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    29. α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in Staphylococcus aureus-Infected Wounds. J Immunol. 2017 09 01; 199(5):1772-1782. Falahee PC, Anderson LS, Reynolds MB, Pirir M, McLaughlin BE, Dillen CA, Cheung AL, Miller LS, Simon SI. PMID: 28733486; PMCID: PMC5568467.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    30. Multifactorial Experimental Design to Optimize the Anti-Inflammatory and Proangiogenic Potential of Mesenchymal Stem Cell Spheroids. Stem Cells. 2017 06; 35(6):1493-1504. Murphy KC, Whitehead J, Falahee PC, Zhou D, Simon SI, Leach JK. PMID: 28276602; PMCID: PMC5446296.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    31. Fond Memories of our Mentor J. David Hellums, Annals of Biomedical Engineering. Ann Biomed Eng. 2016 11; 44(11):3157. Simon SI, Mikos AG, McIntire LV. PMID: 27783234.
      View in: PubMed   Mentions:    Fields:    
    32. The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. Physiol Rep. 2016 Sep; 4(18). Curry FE, Clark JF, Jiang Y, Kim MH, Adamson RH, Simon SI. PMID: 27670406; PMCID: PMC5037917.
      View in: PubMed   Mentions: 4     Fields:    
    33. Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force. Biorheology. 2016 07 04; 53(2):109. Morikis VA, Radecke C, Jiang Y, Heinrich V, Curry FR, Simon SI. PMID: 27392827.
      View in: PubMed   Mentions:    Fields:    
    34. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. J Mol Cell Cardiol. 2016 05; 94:180-188. Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. PMID: 27079253; PMCID: PMC4972711.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    35. Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation. Nat Commun. 2015 Nov 27; 6:8991. Waffarn EE, Hastey CJ, Dixit N, Soo Choi Y, Cherry S, Kalinke U, Simon SI, Baumgarth N. PMID: 26612263; PMCID: PMC4896500.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    36. Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus. Front Immunol. 2015; 6:581. Uchiyama S, Döhrmann S, Timmer AM, Dixit N, Ghochani M, Bhandari T, Timmer JC, Sprague K, Bubeck-Wardenburg J, Simon SI, Nizet V. PMID: 26635795; PMCID: PMC4644796.
      View in: PubMed   Mentions: 34     Fields:    
    37. CD11c/CD18 Signals Very Late Antigen-4 Activation To Initiate Foamy Monocyte Recruitment during the Onset of Hypercholesterolemia. J Immunol. 2015 Dec 01; 195(11):5380-92. Foster GA, Xu L, Chidambaram AA, Soderberg SR, Armstrong EJ, Wu H, Simon SI. PMID: 26519532; PMCID: PMC4655135.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    38. Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo. Blood. 2016 Jan 21; 127(3):314-24. Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A. PMID: 26468229; PMCID: PMC4722285.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    39. Foamy monocytes form early and contribute to nascent atherosclerosis in mice with hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2015 Aug; 35(8):1787-97. Xu L, Dai Perrard X, Perrard JL, Yang D, Xiao X, Teng BB, Simon SI, Ballantyne CM, Wu H. PMID: 26112011; PMCID: PMC4514542.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    40. Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Nat Commun. 2015 Mar 31; 6:6387. Krishnamurthy VR, Sardar MY, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, Simon SI, Woods RJ, Cummings RD, Chaikof EL. PMID: 25824568; PMCID: PMC4423566.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    41. You've got to be kindlin! Blood. 2015 Mar 19; 125(12):1855-6. Simon SI. PMID: 25792733.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    42. Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force. Biorheology. 2015; 52(5-6):447-63. Morikis VA, Radecke C, Jiang Y, Heinrich V, Curry FR, Simon SI. PMID: 26639357; PMCID: PMC5019877.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Coronary artery endothelial cells and microparticles increase expression of VCAM-1 in myocardial infarction. Thromb Haemost. 2015 Mar; 113(3):605-16. Radecke CE, Warrick AE, Singh GD, Rogers JH, Simon SI, Armstrong EJ. PMID: 25413339; PMCID: PMC4479188.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    44. Reversible deactivation of higher-order posterior parietal areas. I. Alterations of receptive field characteristics in early stages of neocortical processing. J Neurophysiol. 2014 Nov 15; 112(10):2529-44. Cooke DF, Goldring AB, Baldwin MK, Recanzone GH, Chen A, Pan T, Simon SI, Krubitzer L. PMID: 25143546; PMCID: PMC4233270.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    45. Reversible deactivation of higher-order posterior parietal areas. II. Alterations in response properties of neurons in areas 1 and 2. J Neurophysiol. 2014 Nov 15; 112(10):2545-60. Goldring AB, Cooke DF, Baldwin MK, Recanzone GH, Gordon AG, Pan T, Simon SI, Krubitzer L. PMID: 25143537; PMCID: PMC4233279.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    46. Mechanosensing at the vascular interface. Annu Rev Biomed Eng. 2014 Jul 11; 16:505-32. Tarbell JM, Simon SI, Curry FR. PMID: 24905872; PMCID: PMC4450720.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    47. Detection of bidirectional signaling during integrin activation and neutrophil adhesion. Methods Mol Biol. 2014; 1124:235-48. Altman SM, Dixit N, Simon SI. PMID: 24504956; PMCID: PMC4438672.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    48. Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS One. 2013; 8(10):e78322. Wang YI, Bettaieb A, Sun C, DeVerse JS, Radecke CE, Mathew S, Edwards CM, Haj FG, Passerini AG, Simon SI. PMID: 24205197; PMCID: PMC3804477.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    49. Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. J Invest Dermatol. 2014 03; 134(3):809-817. Kim MH, Gorouhi F, Ramirez S, Granick JL, Byrne BA, Soulika AM, Simon SI, Isseroff RR. PMID: 24121404; PMCID: PMC4013292.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    50. Clocking leukocytes reveal dynamics of integrin braking. Biophys J. 2013 Sep 03; 105(5):1091-2. Simon SI. PMID: 24010651; PMCID: PMC3762342.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    51. Shear stress modulates VCAM-1 expression in response to TNF-α and dietary lipids via interferon regulatory factor-1 in cultured endothelium. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1149-57. DeVerse JS, Sandhu AS, Mendoza N, Edwards CM, Sun C, Simon SI, Passerini AG. PMID: 23934855; PMCID: PMC3798784.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    52. On-chip phenotypic analysis of inflammatory monocytes in atherogenesis and myocardial infarction. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):13944-9. Foster GA, Gower RM, Stanhope KL, Havel PJ, Simon SI, Armstrong EJ. PMID: 23918401; PMCID: PMC3752270.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    53. Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE2 stimulates granulopoiesis in wounds. Blood. 2013 Sep 05; 122(10):1770-8. Granick JL, Falahee PC, Dahmubed D, Borjesson DL, Miller LS, Simon SI. PMID: 23869087; PMCID: PMC3765058.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    54. Editorial: A missing link? Monocyte activation by uremic toxins in cardiorenal syndrome. J Leukoc Biol. 2013 Jun; 93(6):821-3. Armstrong EJ, Granick JL, Simon SI. PMID: 23723377.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    55. Gimme a brake: HPK1 regulates LFA-1 and neutrophil traction. Blood. 2013 May 16; 121(20):4017-8. Simon SI. PMID: 23682030.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    56. Five simple rules to avoid plagiarism. Ann Biomed Eng. 2013 Jan; 41(1):1-2. Ober H, Simon SI, Elson D. PMID: 23053297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    57. Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog. 2012; 8(11):e1003047. Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. PMID: 23209417; PMCID: PMC3510260.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    58. Magnetic nanoparticle targeted hyperthermia of cutaneous Staphylococcus aureus infection. Ann Biomed Eng. 2013 Mar; 41(3):598-609. Kim MH, Yamayoshi I, Mathew S, Lin H, Nayfach J, Simon SI. PMID: 23149904; PMCID: PMC3740557.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    59. Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation. J Immunol. 2012 Dec 15; 189(12):5954-64. Dixit N, Kim MH, Rossaint J, Yamayoshi I, Zarbock A, Simon SI. PMID: 23144497; PMCID: PMC3723394.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    60. IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal. Circ Res. 2012 Sep 28; 111(8):1054-64. Sun C, Alkhoury K, Wang YI, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG, Simon SI. PMID: 22874466; PMCID: PMC3810165.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    61. Microfluidic system for facilitated quantification of nanoparticle accumulation to cells under laminar flow. Ann Biomed Eng. 2013 Jan; 41(1):89-99. Kusunose J, Zhang H, Gagnon MK, Pan T, Simon SI, Ferrara KW. PMID: 22855121; PMCID: PMC3505813.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    62. On-chip endothelial inflammatory phenotyping. J Vis Exp. 2012 Jul 21; (65):e4169. DeVerse JS, Bailey KA, Foster GA, Mittal V, Altman SM, Simon SI, Passerini AG. PMID: 22847646; PMCID: PMC3476418.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    63. Chemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrest. Front Immunol. 2012; 3:188. Dixit N, Simon SI. PMID: 22787461; PMCID: PMC3392659.
      View in: PubMed   Mentions: 44     Fields:    
    64. Hematopoietic stem and progenitor cells as effectors in innate immunity. Bone Marrow Res. 2012; 2012:165107. Granick JL, Simon SI, Borjesson DL. PMID: 22762001; PMCID: PMC3385697.
      View in: PubMed   Mentions: 25  
    65. Fabrication of an inexpensive, implantable cooling device for reversible brain deactivation in animals ranging from rodents to primates. J Neurophysiol. 2012 Jun; 107(12):3543-58. Cooke DF, Goldring AB, Yamayoshi I, Tsourkas P, Recanzone GH, Tiriac A, Pan T, Simon SI, Krubitzer L. PMID: 22402651; PMCID: PMC3378414.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    66. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochem Biophys Res Commun. 2011 Jul 08; 410(3):494-500. Davis BB, Liu JY, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE. PMID: 21683067; PMCID: PMC3166856.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    67. Migrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium flux. J Immunol. 2011 Jul 01; 187(1):472-81. Dixit N, Yamayoshi I, Nazarian A, Simon SI. PMID: 21632714; PMCID: PMC3414252.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    68. Functional characterization of embryonic stem cell-derived endothelial cells. J Vasc Res. 2011; 48(5):415-28. Glaser DE, Gower RM, Lauer NE, Tam K, Blancas AA, Shih AJ, Simon SI, McCloskey KE. PMID: 21625175; PMCID: PMC3121553.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    69. Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. 2011 Mar 24; 117(12):3343-52. Kim MH, Granick JL, Kwok C, Walker NJ, Borjesson DL, Curry FR, Miller LS, Simon SI. PMID: 21278352; PMCID: PMC3069674.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    70. Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections. J Invest Dermatol. 2011 Apr; 131(4):907-15. Cho JS, Zussman J, Donegan NP, Ramos RI, Garcia NC, Uslan DZ, Iwakura Y, Simon SI, Cheung AL, Modlin RL, Kim J, Miller LS. PMID: 21191403; PMCID: PMC3059384.
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    71. Endothelial inflammation correlates with subject triglycerides and waist size after a high-fat meal. Am J Physiol Heart Circ Physiol. 2011 Mar; 300(3):H784-91. Wang YI, Schulze J, Raymond N, Tomita T, Tam K, Simon SI, Passerini AG. PMID: 21169396; PMCID: PMC3064298.
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    72. CD11c/CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1. Arterioscler Thromb Vasc Biol. 2011 Jan; 31(1):160-6. Gower RM, Wu H, Foster GA, Devaraj S, Jialal I, Ballantyne CM, Knowlton AA, Simon SI. PMID: 21030716; PMCID: PMC3038249.
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    73. Mightier than the sickle cell. Blood. 2010 Sep 09; 116(10):1633. Simon SI, Wun T. PMID: 20829378.
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    74. A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings. PLoS One. 2010 Sep 07; 5(9):e12580. Bernthal NM, Stavrakis AI, Billi F, Cho JS, Kremen TJ, Simon SI, Cheung AL, Finerman GA, Lieberman JR, Adams JS, Miller LS. PMID: 20830204; PMCID: PMC2935351.
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    75. A day (or 5) in a neutrophil's life. Blood. 2010 Jul 29; 116(4):511-2. Simon SI, Kim MH. PMID: 20671133.
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    76. Long-lived, high-strength states of ICAM-1 bonds to beta2 integrin, II: lifetimes of LFA-1 bonds under force in leukocyte signaling. Biophys J. 2010 Apr 21; 98(8):1467-75. Kinoshita K, Leung A, Simon S, Evans E. PMID: 20409465; PMCID: PMC2856185.
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    77. Long-lived, high-strength states of ICAM-1 bonds to beta2 integrin, I: lifetimes of bonds to recombinant alphaLbeta2 under force. Biophys J. 2010 Apr 21; 98(8):1458-66. Evans E, Kinoshita K, Simon S, Leung A. PMID: 20409464; PMCID: PMC2856188.
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    78. Comparative analysis of normal versus CLL B-lymphocytes reveals patient-specific variability in signaling mechanisms controlling LFA-1 activation by chemokines. Cancer Res. 2009 Dec 15; 69(24):9281-90. Montresor A, Bolomini-Vittori M, Simon SI, Rigo A, Vinante F, Laudanna C. PMID: 19934331.
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    79. Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow. Blood. 2010 Jan 21; 115(3):657-66. Schaff UY, Dixit N, Procyk E, Yamayoshi I, Tse T, Simon SI. PMID: 19965684; PMCID: PMC2810981.
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    80. Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J Immunol. 2009 Jun 01; 182(11):6870-8. Phillipson M, Heit B, Parsons SA, Petri B, Mullaly SC, Colarusso P, Gower RM, Neely G, Simon SI, Kubes P. PMID: 19454683; PMCID: PMC4017595.
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    81. Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia. Circulation. 2009 May 26; 119(20):2708-17. Wu H, Gower RM, Wang H, Perrard XY, Ma R, Bullard DC, Burns AR, Paul A, Smith CW, Simon SI, Ballantyne CM. PMID: 19433759; PMCID: PMC2716173.
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    82. Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding. Am J Physiol Cell Physiol. 2009 Apr; 296(4):C848-56. Kim MH, Curry FR, Simon SI. PMID: 19176758; PMCID: PMC2670654.
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    83. Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. J Immunol. 2008 Dec 15; 181(12):8660-9. Sarantos MR, Zhang H, Schaff UY, Dixit N, Hayenga HN, Lowell CA, Simon SI. PMID: 19050286; PMCID: PMC4457456.
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    84. Leucocyte recruitment under fluid shear: mechanical and molecular regulation within the inflammatory synapse. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):217-24. Simon SI, Sarantos MR, Green CE, Schaff UY. PMID: 19018799.
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    85. E-selectin prefers fatty-sweet receptors on rolling neutrophils. Blood. 2008 Nov 01; 112(9):3537. Simon SI. PMID: 18948585; PMCID: PMC2572786.
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    86. Spatial regulation of inflammation by human aortic endothelial cells in a linear gradient of shear stress. Microcirculation. 2008 May; 15(4):311-23. Tsou JK, Gower RM, Ting HJ, Schaff UY, Insana MF, Passerini AG, Simon SI. PMID: 18464160; PMCID: PMC2733907.
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    87. Differential regulation of neutrophil CD18 integrin function by di- and tri-valent cations: manganese vs. gadolinium. Ann Biomed Eng. 2008 Apr; 36(4):647-60. Zhang Y, Hayenga HN, Sarantos MR, Simon SI, Neelamegham S. PMID: 18317931.
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    88. Calcium flux in neutrophils synchronizes beta2 integrin adhesive and signaling events that guide inflammatory recruitment. Ann Biomed Eng. 2008 Apr; 36(4):632-46. Schaff UY, Yamayoshi I, Tse T, Griffin D, Kibathi L, Simon SI. PMID: 18278555; PMCID: PMC2668576.
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    89. Hydrodynamic shear rate regulates melanoma-leukocyte aggregation, melanoma adhesion to the endothelium, and subsequent extravasation. Ann Biomed Eng. 2008 Apr; 36(4):661-71. Liang S, Slattery MJ, Wagner D, Simon SI, Dong C. PMID: 18253835; PMCID: PMC2677444.
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    90. SLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1. Eur J Immunol. 2008 Feb; 38(2):550-64. Schaff UY, Shih HH, Lorenz M, Sako D, Kriz R, Milarski K, Bates B, Tchernychev B, Shaw GD, Simon SI. PMID: 18196517; PMCID: PMC3414251.
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    91. Fluid shear-induced activation and cleavage of CD18 during pseudopod retraction by human neutrophils. J Cell Physiol. 2008 Feb; 214(2):528-36. Shin HY, Simon SI, Schmid-Schönbein GW. PMID: 17676580.
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    92. Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol. 2008 Jul; 128(7):1812-20. Kim MH, Liu W, Borjesson DL, Curry FR, Miller LS, Cheung AL, Liu FT, Isseroff RR, Simon SI. PMID: 18185533; PMCID: PMC2617712.
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    93. Neutrophil adhesion to E-selectin under shear promotes the redistribution and co-clustering of ADAM17 and its proteolytic substrate L-selectin. J Leukoc Biol. 2008 Jan; 83(1):99-105. Schaff U, Mattila PE, Simon SI, Walcheck B. PMID: 17928459.
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    94. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007 Jun; 81(6):1395-403. Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, Staunton DE. PMID: 17389580.
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    95. Mechanisms of B-cell synapse formation predicted by Monte Carlo simulation. Biophys J. 2007 Jun 15; 92(12):4196-208. Tsourkas PK, Baumgarth N, Simon SI, Raychaudhuri S. PMID: 17384077; PMCID: PMC1877775.
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    96. Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer. Ann Biomed Eng. 2007 Apr; 35(4):595-604. Simon SI, Nyunt T, Florine-Casteel K, Ritchie K, Ting-Beall HP, Evans E, Needham D. PMID: 17370125.
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    97. Vascular mimetics based on microfluidics for imaging the leukocyte--endothelial inflammatory response. Lab Chip. 2007 Apr; 7(4):448-56. Schaff UY, Xing MM, Lin KK, Pan N, Jeon NL, Simon SI. PMID: 17389960.
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    98. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circ Res. 2007 Feb 16; 100(3):381-90. Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG, Simon SI. PMID: 17234968.
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    99. Polyurethane shape-memory polymers demonstrate functional biocompatibility in vitro. Macromol Biosci. 2007 Jan 05; 7(1):48-55. Cabanlit M, Maitland D, Wilson T, Simon S, Wun T, Gershwin ME, Van de Water J. PMID: 17238230.
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    100. Optical and fluorescence detection of neutrophil integrin activation. Methods Mol Biol. 2007; 412:203-10. Schaff UY, Sarantos MR, Ting H, Simon SI. PMID: 18453113.
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    101. The integrins. Genome Biol. 2007; 8(5):215. Takada Y, Ye X, Simon S. PMID: 17543136; PMCID: PMC1929136.
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    102. Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity. 2006 Aug; 25(2):285-95. Zhang H, Schaff UY, Green CE, Chen H, Sarantos MR, Hu Y, Wara D, Simon SI, Lowell CA. PMID: 16901726; PMCID: PMC4698343.
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    103. Ultrasound radiation force modulates ligand availability on targeted contrast agents. Mol Imaging. 2006 Jul; 5(3):139-47. Borden MA, Sarantos MR, Stieger SM, Simon SI, Ferrara KW, Dayton PA. PMID: 16954028; PMCID: PMC1636845.
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    104. CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions. Am J Physiol Heart Circ Physiol. 2006 Sep; 291(3):H1170-6. Devaraj S, Davis B, Simon SI, Jialal I. PMID: 16603696.
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    105. Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles. J Control Release. 2006 Mar 10; 111(1-2):128-34. Lum AF, Borden MA, Dayton PA, Kruse DE, Simon SI, Ferrara KW. PMID: 16380187; PMCID: PMC1526414.
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    106. Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium. Blood. 2006 Mar 01; 107(5):2101-11. Green CE, Schaff UY, Sarantos MR, Lum AF, Staunton DE, Simon SI. PMID: 16269618; PMCID: PMC1895714.
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    107. Leukocyte function-associated antigen 1-mediated adhesion stability is dynamically regulated through affinity and valency during bond formation with intercellular adhesion molecule-1. J Biol Chem. 2005 Aug 05; 280(31):28290-8. Sarantos MR, Raychaudhuri S, Lum AF, Staunton DE, Simon SI. PMID: 15955822.
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    108. Cytoskeletal interactions regulate inducible L-selectin clustering. Am J Physiol Cell Physiol. 2005 Aug; 289(2):C323-32. Mattila PE, Green CE, Schaff U, Simon SI, Walcheck B. PMID: 15788481.
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    109. Rolling dynamics of a neutrophil with redistributed L-selectin. Math Biosci. 2005 Mar; 194(1):71-9. King MR, Sumagin R, Green CE, Simon SI. PMID: 15836865.
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    110. Molecular mechanics and dynamics of leukocyte recruitment during inflammation. Annu Rev Biomed Eng. 2005; 7:151-85. Simon SI, Green CE. PMID: 16004569.
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    111. Cooperativity between selectins and beta2-integrins define neutrophil capture and stable adhesion in shear flow. Ann Biomed Eng. 2004 Sep; 32(9):1179-92. McDonough DB, McIntosh FA, Spanos C, Neelamegham S, Goldsmith HL, Simon SI. PMID: 15493506.
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    112. Shear-dependent capping of L-selectin and P-selectin glycoprotein ligand 1 by E-selectin signals activation of high-avidity beta2-integrin on neutrophils. J Immunol. 2004 Jun 15; 172(12):7780-90. Green CE, Pearson DN, Camphausen RT, Staunton DE, Simon SI. PMID: 15187162.
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    113. Inflammatory potential of neutrophils detected in sickle cell disease. Am J Hematol. 2004 Jun; 76(2):126-33. Lum AF, Wun T, Staunton D, Simon SI. PMID: 15164377.
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    114. Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of alphavbeta3-expressing cells. Mol Imaging. 2004 Apr; 3(2):125-34. Dayton PA, Pearson D, Clark J, Simon S, Schumann PA, Zutshi R, Matsunaga TO, Ferrara KW. PMID: 15296677; PMCID: PMC2481513.
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    115. Roles of neutrophil beta 2 integrins in kinetics of bacteremia, extravasation, and tick acquisition of Anaplasma phagocytophila in mice. Blood. 2003 Apr 15; 101(8):3257-64. Borjesson DL, Simon SI, Hodzic E, DeCock HE, Ballantyne CM, Barthold SW. PMID: 12480703.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    116. Topographic requirements and dynamics of signaling via L-selectin on neutrophils. Am J Physiol Cell Physiol. 2003 Mar; 284(3):C705-17. Green CE, Pearson DN, Christensen NB, Simon SI. PMID: 12431911.
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    117. Hydrodynamic shear and tethering through E-selectin signals phosphorylation of p38 MAP kinase and adhesion of human neutrophils. Ann Biomed Eng. 2002 Sep; 30(8):987-1001. Hentzen E, McDonough D, McIntire L, Smith CW, Goldsmith HL, Simon SI. PMID: 12449760.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    118. Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow. J Biol Chem. 2002 Jun 07; 277(23):20660-70. Lum AF, Green CE, Lee GR, Staunton DE, Simon SI. PMID: 11929876.
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    119. Leukocyte adhesion dynamics in shear flow. Ann Biomed Eng. 2002 Mar; 30(3):315-32. Simon SI, Goldsmith HL. PMID: 12051617.
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    120. Kinetics of CD11b/CD18 up-regulation during infection with the agent of human granulocytic ehrlichiosis in mice. Lab Invest. 2002 Mar; 82(3):303-11. Borjesson DL, Simon SI, Hodzic E, Ballantyne CM, Barthold SW. PMID: 11896209.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    121. Neutrophil tethering on E-selectin activates beta 2 integrin binding to ICAM-1 through a mitogen-activated protein kinase signal transduction pathway. J Immunol. 2000 Apr 15; 164(8):4348-58. Simon SI, Hu Y, Vestweber D, Smith CW. PMID: 10754335.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells