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Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer. Cancer Immunol Res. 2024 Oct 01; 12(10):1468-1484.
Liao TT, Chen YH, Li ZY, Hsiao AC, Huang YL, Hao RX, Tai SK, Chu PY, Shih JW, Kung HJ, Yang MH. PMID: 38920249; PMCID: PMC11443317.
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PubMed Mentions: Fields:
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Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2. Nat Commun. 2024 Aug 29; 15(1):7463.
Wang RH, Chen PR, Chen YT, Chen YC, Chu YH, Chien CC, Chien PC, Lo SY, Wang ZL, Tsou MC, Chen SY, Chiu GS, Chen WL, Wu YH, Wang LH, Wang WC, Lin SY, Kung HJ, Wang LH, Cheng HC, Lin KT. PMID: 39198443; PMCID: PMC11358145.
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Translation:
HumansAnimalsCells
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L1CAM mediates neuroendocrine phenotype acquisition in prostate cancer cells. Prostate. 2024 Aug 18.
Hsieh CL, Do AD, Hsueh CY, Raboshakga MO, Thanh TN, Tai TT, Kung HJ, Sung SY. PMID: 39154281.
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PubMed Mentions: Fields:
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PROTACs as Therapeutic Modalities for Drug Discovery in Castration-Resistant Prostate Cancer. Annu Rev Pharmacol Toxicol. 2024 Aug 08.
Wang LY, Hung CL, Wang TC, Hsu HC, Kung HJ, Lin KH. PMID: 39116434.
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PubMed Mentions: Fields:
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The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells. Cancer Med. 2024 Aug; 13(16):e70106.
Huo C, Kuo YY, Lin CY, Shiah SG, Li CY, Huang SP, Chen JK, Wang WC, Kung HJ, Chuu CP. PMID: 39149855; PMCID: PMC11327718.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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REST-repressed lncRNA LINC01801 induces neuroendocrine differentiation in prostate cancer via transcriptional activation of autophagy. Am J Cancer Res. 2023; 13(9):3983-4002.
Chang CH, Cheng TY, Yeh WW, Luo YL, Campbell M, Kuo TC, Shen TW, Hong YC, Tsai CH, Peng YC, Pan CC, Yang MH, Shih JC, Kung HJ, Huang WJ, Chang PC, Lin TP. PMID: 37818052; PMCID: PMC10560947.
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PubMed Mentions:
3
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Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis. J Biomed Sci. 2023 May 22; 30(1):32.
Hung YW, Ouyang C, Ping X, Qi Y, Wang YC, Kung HJ, Ann DK. PMID: 37217939; PMCID: PMC10201738.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination. Cell Rep. 2023 04 25; 42(4):112296.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Taglialatela A, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK. PMID: 36961817; PMCID: PMC10517088.
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PubMed Mentions: Fields:
Translation:
Cells
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Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer. EBioMedicine. 2023 Apr; 90:104500.
Hung CL, Liu HH, Fu CW, Yeh HH, Hu TL, Kuo ZK, Lin YC, Jhang MR, Hwang CS, Hsu HC, Kung HJ, Wang LY. PMID: 36893587; PMCID: PMC10011747.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination. bioRxiv. 2023 Feb 03.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK. PMID: 36778247; PMCID: PMC9915598.
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Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer. J Biomed Sci. 2022 May 09; 29(1):29.
Liu JS, Fang WK, Yang SM, Wu MC, Chen TJ, Chen CM, Lin TY, Liu KL, Wu CM, Chen YC, Chuu CP, Wang LY, Hsieh HP, Kung HJ, Wang WC. PMID: 35534851; PMCID: PMC9082844.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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TEAD4 as an Oncogene and a Mitochondrial Modulator. Front Cell Dev Biol. 2022; 10:890419.
Hsu SC, Lin CY, Lin YY, Collins CC, Chen CL, Kung HJ. PMID: 35602596; PMCID: PMC9117765.
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PubMed Mentions:
7
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Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511.
Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Inhibition of KDM4C/c-Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism. Clin Transl Med. 2022 03; 12(3):e764.
Lin CY, Wang BJ, Fu YK, Huo C, Wang YP, Chen BC, Liu WY, Tseng JC, Jiang SS, Sie ZL, Tsai KK, Yuh CH, Wang WC, Kung HJ, Chuu CP. PMID: 35343073; PMCID: PMC8958350.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Targeting Mitochondrial OXPHOS and Their Regulatory Signals in Prostate Cancers. Int J Mol Sci. 2021 Dec 14; 22(24).
Chen CL, Lin CY, Kung HJ. PMID: 34948229; PMCID: PMC8708687.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain Aging. Biomedicines. 2021 Nov 07; 9(11).
Chao CC, Shen PW, Tzeng TY, Kung HJ, Tsai TF, Wong YH. PMID: 34829864; PMCID: PMC8615703.
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PubMed Mentions:
2
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Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance. Acta Pharm Sin B. 2022 Apr; 12(4):1871-1884.
Wang H, Wang Q, Cai G, Duan Z, Nugent Z, Huang J, Zheng J, Borowsky AD, Li JJ, Liu P, Kung HJ, Murphy L, Chen HW, Wang J. PMID: 35847493; PMCID: PMC9279715.
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PubMed Mentions:
8
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Prognostic Significance of O-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer. Diagnostics (Basel). 2021 Aug 12; 11(8).
Kuo WL, Tseng LL, Chang CC, Chen CJ, Cheng ML, Cheng HH, Wu MJ, Chen YL, Chang RT, Tang HY, Hsu YC, Lin WJ, Kao CY, Hsieh WP, Kung HJ, Wang WC. PMID: 34441396; PMCID: PMC8392504.
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PubMed Mentions:
2
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Arginine Signaling and Cancer Metabolism. Cancers (Basel). 2021 Jul 15; 13(14).
Chen CL, Hsu SC, Ann DK, Yen Y, Kung HJ. PMID: 34298755; PMCID: PMC8306961.
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PubMed Mentions:
67
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Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer. Theranostics. 2021; 11(16):7779-7796.
Wu MJ, Chen CJ, Lin TY, Liu YY, Tseng LL, Cheng ML, Chuu CP, Tsai HK, Kuo WL, Kung HJ, Wang WC. PMID: 34335964; PMCID: PMC8315051.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes. Theranostics. 2021; 11(15):7527-7545.
Hsu SC, Chen CL, Cheng ML, Chu CY, Changou CA, Yu YL, Yeh SD, Kuo TC, Kuo CC, Chuu CP, Li CF, Wang LH, Chen HW, Yen Y, Ann DK, Wang HJ, Kung HJ. PMID: 34158865; PMCID: PMC8210599.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Long Non-Coding RNAs as Functional Codes for Oral Cancer: Translational Potential, Progress and Promises. Int J Mol Sci. 2021 May 05; 22(9).
Lei CS, Kung HJ, Shih JW. PMID: 34063159; PMCID: PMC8124393.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells. Nat Commun. 2021 04 23; 12(1):2398.
Chen CL, Hsu SC, Chung TY, Chu CY, Wang HJ, Hsiao PW, Yeh SD, Ann DK, Yen Y, Kung HJ. PMID: 33893278; PMCID: PMC8065123.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy. Theranostics. 2021; 11(8):3624-3641.
Chu CY, Lee YC, Hsieh CH, Yeh CT, Chao TY, Chen PH, Lin IH, Hsieh TH, Shih JW, Cheng CH, Chang CC, Lin PS, Huang YL, Chen TM, Yen Y, Ann DK, Kung HJ. PMID: 33664852; PMCID: PMC7914361.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer. Proc Natl Acad Sci U S A. 2020 10 06; 117(40):24859-24866.
Tseng LL, Cheng HH, Yeh TS, Huang SC, Syu YY, Chuu CP, Yuh CH, Kung HJ, Wang WC. PMID: 32958674; PMCID: PMC7547212.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Signaling in and out: long-noncoding RNAs in tumor hypoxia. J Biomed Sci. 2020 May 05; 27(1):59.
Kuo TC, Kung HJ, Shih JW. PMID: 32370770; PMCID: PMC7201962.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs. Aging Cell. 2020 05; 19(5):e13107.
Yang CP, Yang WS, Wong YH, Wang KH, Teng YC, Chang MH, Liao KH, Nian FS, Chao CC, Tsai JW, Hwang WL, Lin MW, Tzeng TY, Wang PN, Campbell M, Chen LK, Tsai TF, Chang PC, Kung HJ. PMID: 32233025; PMCID: PMC7253071.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor. Mol Cell. 2020 01 16; 77(2):213-227.e5.
Wu JY, Huang TW, Hsieh YT, Wang YF, Yen CC, Lee GL, Yeh CC, Peng YJ, Kuo YY, Wen HT, Lin HC, Hsiao CW, Wu KK, Kung HJ, Hsu YJ, Kuo CC. PMID: 31735641.
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PubMed Mentions:
185 Fields:
Translation:
HumansAnimalsCells
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Histone Demethylase KDM4C Stimulates the Proliferation of Prostate Cancer Cells via Activation of AKT and c-Myc. Cancers (Basel). 2019 Nov 13; 11(11).
Lin CY, Wang BJ, Chen BC, Tseng JC, Jiang SS, Tsai KK, Shen YY, Yuh CH, Sie ZL, Wang WC, Kung HJ, Chuu CP. PMID: 31766290; PMCID: PMC6896035.
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PubMed Mentions:
16
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RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 10 11; 10(1):4621.
Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. PMID: 31604910; PMCID: PMC6789042.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis. EMBO Rep. 2019 10 04; 20(10):e45986.
Wang YH, Huang JT, Chen WL, Wang RH, Kao MC, Pan YR, Chan SH, Tsai KW, Kung HJ, Lin KT, Wang LH. PMID: 31468690; PMCID: PMC6776913.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation. Commun Biol. 2019; 2:105.
Chen TJ, Wang HJ, Liu JS, Cheng HH, Hsu SC, Wu MC, Lu CH, Wu YF, Wu JW, Liu YY, Kung HJ, Wang WC. PMID: 30911680; PMCID: PMC6420622.
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PubMed Mentions:
12 Translation:
HumansCells
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Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation. Commun Biol. 2019 Mar 15; 2(1):105.
Chen TJ, Wang HJ, Liu JS, Cheng HH, Hsu SC, Wu MC, Lu CH, Wu YF, Wu JW, Liu YY, Kung HJ, Wang WC. PMID: 31924980.
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PubMed Mentions:
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KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis. Cell Death Dis. 2019 01 25; 10(2):68.
Wu MC, Cheng HH, Yeh TS, Li YC, Chen TJ, Sit WY, Chuu CP, Kung HJ, Chien S, Wang WC. PMID: 30683841; PMCID: PMC6347645.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction. Commun Biol. 2018; 1:178.
Cheng CT, Qi Y, Wang YC, Chi KK, Chung Y, Ouyang C, Chen YR, Oh ME, Sheng X, Tang Y, Liu YR, Lin HH, Kuo CY, Schones D, Vidal CM, Chu JC, Wang HJ, Chen YH, Miller KM, Chu P, Yen Y, Jiang L, Kung HJ, Ann DK. PMID: 30393775; PMCID: PMC6203837.
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PubMed Mentions:
65
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Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis. Autophagy. 2018; 14(9):1481-1498.
Lin HH, Chung Y, Cheng CT, Ouyang C, Fu Y, Kuo CY, Chi KK, Sadeghi M, Chu P, Kung HJ, Li CF, Limesand KH, Ann DK. PMID: 29956571; PMCID: PMC6135591.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. Oncogene. 2019 01; 38(1):17-32.
Wang HJ, Pochampalli M, Wang LY, Zou JX, Li PS, Hsu SC, Wang BJ, Huang SH, Yang P, Yang JC, Chu CY, Hsieh CL, Sung SY, Li CF, Tepper CG, Ann DK, Gao AC, Evans CP, Izumiya Y, Chuu CP, Wang WC, Chen HW, Kung HJ. PMID: 30072740; PMCID: PMC6755995.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer. Cancer Lett. 2018 10 01; 433:43-52.
Chang YT, Lin TP, Tang JT, Campbell M, Luo YL, Lu SY, Yang CP, Cheng TY, Chang CH, Liu TT, Lin CH, Kung HJ, Pan CC, Chang PC. PMID: 29944905.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion. Clin Cancer Res. 2018 09 01; 24(17):4319-4331.
Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss S, Wang T, Chen XJ, Carney R, Kung HJ, Duan Y, Ghosh PM, Lam KS. PMID: 29666302; PMCID: PMC6125207.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity. J Vis Exp. 2018 01 29; (131).
Yang WS, Campbell M, Kung HJ, Chang PC. PMID: 29443041; PMCID: PMC5912215.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena. J Biomed Sci. 2017 Aug 08; 24(1):53.
Shih JW, Kung HJ. PMID: 28789687; PMCID: PMC5547530.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis. Oncogene. 2017 11 23; 36(47):6542-6554.
Shih CH, Chang YJ, Huang WC, Jang TH, Kung HJ, Wang WC, Yang MH, Lin MC, Huang SF, Chou SW, Chang E, Chiu H, Shieh TY, Chen YJ, Wang LH, Chen L. PMID: 28759046; PMCID: PMC5702718.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression. Nat Commun. 2017 06 22; 8:15874.
Shih JW, Chiang WF, Wu ATH, Wu MH, Wang LY, Yu YL, Hung YW, Wang WC, Chu CY, Hung CL, Changou CA, Yen Y, Kung HJ. PMID: 28639619; PMCID: PMC5489688.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimals
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ITK inhibition for the targeted treatment of CTCL. J Dermatol Sci. 2017 Jul; 87(1):88-91.
Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E. PMID: 28434812; PMCID: PMC6459605.
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PubMed Mentions: Fields:
Translation:
HumansCells
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REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017 03 03; 7:42795.
Chang YT, Lin TP, Campbell M, Pan CC, Lee SH, Lee HC, Yang MH, Kung HJ, Chang PC. PMID: 28256535; PMCID: PMC5335619.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis. Cell Rep. 2016 09 13; 16(11):3016-3027.
Wang LY, Hung CL, Chen YR, Yang JC, Wang J, Campbell M, Izumiya Y, Chen HW, Wang WC, Ann DK, Kung HJ. PMID: 27626669; PMCID: PMC5024724.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy. Cell Death Differ. 2016 11 01; 23(11):1886-1896.
Wang J, Wang H, Wang LY, Cai D, Duan Z, Zhang Y, Chen P, Zou JX, Xu J, Chen X, Kung HJ, Chen HW. PMID: 27612013; PMCID: PMC5071577.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Retraction: MMP-13 is involved in oral cancer cell metastasis. Oncotarget. 2016 07 26; 7(30):48851.
Huang SH, Law CH, Kuo PH, Hu RY, Yang CC, Chung TW, Li JM, Lin LH, Liu YC, Liao EC, Tsai YT, Wei YS, Lin CC, Chang CW, Chou HC, Wang WC, Chang MD, Wang LH, Kung HJ, Chan HL, Lyu PC. PMID: 27885991; PMCID: PMC5217056.
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Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells. Cancer Res. 2016 09 01; 76(17):5006-18.
Cheng CT, Kuo CY, Ouyang C, Li CF, Chung Y, Chan DC, Kung HJ, Ann DK. PMID: 27364555; PMCID: PMC5316485.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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A viral kinase mimics S6 kinase to enhance cell proliferation. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):7876-81.
Bhatt AP, Wong JP, Weinberg MS, Host KM, Giffin LC, Buijnink J, van Dijk E, Izumiya Y, Kung HJ, Temple BR, Damania B. PMID: 27342859; PMCID: PMC4948314.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity. Oncotarget. 2016 Jun 07; 7(23):34052-69.
Kuo CY, Cheng CT, Hou P, Lin YP, Ma H, Chung Y, Chi K, Chen Y, Li W, Kung HJ, Ann DK. PMID: 27058900; PMCID: PMC5085137.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nat Med. 2016 06 07; 22(6):692.
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW. PMID: 27270780.
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PubMed Mentions:
5 Fields:
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Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes. Cancer Lett. 2016 08 10; 378(2):69-79.
Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. PMID: 27164560; PMCID: PMC7505026.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. 2016 May 03; 7(18):26137-51.
Lin TP, Chang YT, Lee SY, Campbell M, Wang TC, Shen SH, Chung HJ, Chang YH, Chiu AW, Pan CC, Lin CH, Chu CY, Kung HJ, Cheng CY, Chang PC. PMID: 27034167; PMCID: PMC5041970.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening. ACS Comb Sci. 2016 06 13; 18(6):320-9.
Wu CY, Wang DH, Wang X, Dixon SM, Meng L, Ahadi S, Enter DH, Chen CY, Kato J, Leon LJ, Ramirez LM, Maeda Y, Reis CF, Ribeiro B, Weems B, Kung HJ, Lam KS. PMID: 27053324; PMCID: PMC4908505.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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MMP-13 is involved in oral cancer cell metastasis. Oncotarget. 2016 03 29; 7(13):17144-61.
Huang SH, Law CH, Kuo PH, Hu RY, Yang CC, Chung TW, Li JM, Lin LH, Liu YC, Liao EC, Tsai YT, Wei YS, Lin CC, Chang CW, Chou HC, Wang WC, Chang MD, Wang LH, Kung HJ, Chan HL, Lyu PC. PMID: 26958809; PMCID: PMC4941377.
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PubMed Mentions:
14 Fields:
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ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nat Med. 2016 05; 22(5):488-96.
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW. PMID: 27019329; PMCID: PMC5030109.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
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2804 Fields:
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HumansAnimals
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Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism. Int J Mol Sci. 2015 Dec 04; 16(12):28943-78.
Shih JW, Wang LY, Hung CL, Kung HJ, Hsieh CL. PMID: 26690121; PMCID: PMC4691085.
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12 Fields:
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HumansAnimalsCells
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miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src. Cancer Res. 2015 Dec 15; 75(24):5309-17.
Shi XB, Ma AH, Xue L, Li M, Nguyen HG, Yang JC, Tepper CG, Gandour-Edwards R, Evans CP, Kung HJ, deVere White RW. PMID: 26573802; PMCID: PMC4681619.
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PubMed Mentions:
34 Fields:
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HumansAnimalsCells
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AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf, and TSC1/TSC2. Oncotarget. 2015 Sep 29; 6(29):27097-112.
Lin HP, Lin CY, Huo C, Jan YJ, Tseng JC, Jiang SS, Kuo YY, Chen SC, Wang CT, Chan TM, Liou JY, Wang J, Chang WS, Chang CH, Kung HJ, Chuu CP. PMID: 26318033; PMCID: PMC4694976.
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27 Fields:
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HumansAnimalsCells
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Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells. PLoS One. 2015; 10(4):e0125518.
Wen HC, Chuu CP, Chen CY, Shiah SG, Kung HJ, King KL, Su LC, Chang SC, Chang CH. PMID: 25928539; PMCID: PMC4416047.
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16 Fields:
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HumansAnimalsCells
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Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. Oncotarget. 2015 Mar 30; 6(9):6684-707.
Lin HP, Lin CY, Huo C, Hsiao PH, Su LC, Jiang SS, Chan TM, Chang CH, Chen LT, Kung HJ, Wang HD, Chuu CP. PMID: 25788262; PMCID: PMC4466643.
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31 Fields:
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HumansAnimalsCells
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Chromatophagy: autophagy goes nuclear and captures broken chromatin during arginine-starvation. Autophagy. 2015; 11(2):419-21.
Kung HJ, Changou CA, Li CF, Ann DK. PMID: 25650867; PMCID: PMC4502812.
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9 Fields:
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HumansCells
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A long noncoding RNA connects c-Myc to tumor metabolism. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18697-702.
Hung CL, Wang LY, Yu YL, Chen HW, Srivastava S, Petrovics G, Kung HJ. PMID: 25512540; PMCID: PMC4284533.
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169 Fields:
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HumansCells
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Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance. Oncotarget. 2014 Nov 30; 5(22):11428-41.
Li CF, Fang FM, Kung HJ, Chen LT, Wang JW, Tsai JW, Yu SC, Wang YH, Li SH, Huang HY. PMID: 25426549; PMCID: PMC4294342.
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18 Fields:
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HumansAnimalsCells
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AMACR amplification in myxofibrosarcomas: a mechanism of overexpression that promotes cell proliferation with therapeutic relevance. Clin Cancer Res. 2014 Dec 01; 20(23):6141-52.
Li CF, Fang FM, Lan J, Wang JW, Kung HJ, Chen LT, Chen TJ, Li SH, Wang YH, Tai HC, Yu SC, Huang HY. PMID: 25384383.
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PubMed Mentions:
19 Fields:
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HumansAnimalsCells
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Long non-coding RNA and epigenetic gene regulation of KSHV. Viruses. 2014 Nov 04; 6(11):4165-77.
Campbell M, Kung HJ, Izumiya Y. PMID: 25375882; PMCID: PMC4246214.
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20 Fields:
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HumansCells
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SUMO and KSHV Replication. Cancers (Basel). 2014 Sep 29; 6(4):1905-24.
Chang PC, Kung HJ. PMID: 25268162; PMCID: PMC4276950.
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10
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Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death Dis. 2014 Sep 04; 5:e1409.
Guo W, Liu R, Bhardwaj G, Yang JC, Changou C, Ma AH, Mazloom A, Chintapalli S, Xiao K, Xiao W, Kumaresan P, Sanchez E, Yeh CT, Evans CP, Patterson R, Lam KS, Kung HJ. PMID: 25188519; PMCID: PMC4540187.
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23 Fields:
Translation:
HumansAnimalsCells
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Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy. Proc Natl Acad Sci U S A. 2014 Sep 30; 111(39):14147-52.
Changou CA, Chen YR, Xing L, Yen Y, Chuang FY, Cheng RH, Bold RJ, Ann DK, Kung HJ. PMID: 25122679; PMCID: PMC4191793.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J Med Chem. 2014 Jul 24; 57(14):5975-85.
Chu CH, Wang LY, Hsu KC, Chen CC, Cheng HH, Wang SM, Wu CM, Chen TJ, Li LT, Liu R, Hung CL, Yang JM, Kung HJ, Wang WC. PMID: 24971742; PMCID: PMC4216216.
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46 Fields:
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HumansCells
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Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells. Sci Signal. 2014 Apr 01; 7(319):ra31.
Qiu F, Chen YR, Liu X, Chu CY, Shen LJ, Xu J, Gaur S, Forman HJ, Zhang H, Zheng S, Yen Y, Huang J, Kung HJ, Ann DK. PMID: 24692592; PMCID: PMC4229039.
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PubMed Mentions:
94 Fields:
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HumansAnimalsCells
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Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model. Oncogene. 2014 Sep 04; 33(36):4521-30.
Nguyen HG, Yang JC, Kung HJ, Shi XB, Tilki D, Lara PN, DeVere White RW, Gao AC, Evans CP. PMID: 24662833; PMCID: PMC4155805.
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PubMed Mentions:
103 Fields:
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HumansAnimalsCells
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Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS One. 2014; 9(2):e88556.
Chang PC, Wang TY, Chang YT, Chu CY, Lee CL, Hsu HW, Zhou TA, Wu Z, Kim RH, Desai SJ, Liu S, Kung HJ. PMID: 24551118; PMCID: PMC3925144.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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An improved ChIP-seq peak detection system for simultaneously identifying post-translational modified transcription factors by combinatorial fusion, using SUMOylation as an example. BMC Genomics. 2014; 15 Suppl 1:S1.
Cheng CY, Chu CH, Hsu HW, Hsu FR, Tang CY, Wang WC, Kung HJ, Chang PC. PMID: 24564277; PMCID: PMC4046823.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. PLoS Pathog. 2013; 9(12):e1003813.
Toth Z, Brulois K, Lee HR, Izumiya Y, Tepper C, Kung HJ, Jung JU. PMID: 24367262; PMCID: PMC3868514.
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PubMed Mentions:
66 Fields:
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HumansCells
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JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):279-84.
Wang HJ, Hsieh YJ, Cheng WC, Lin CP, Lin YS, Yang SF, Chen CC, Izumiya Y, Yu JS, Kung HJ, Wang WC. PMID: 24344305; PMCID: PMC3890888.
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PubMed Mentions:
161 Fields:
Translation:
HumansCells
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Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells. PLoS One. 2013; 8(12):e82625.
Lin HP, Lin CY, Hsiao PH, Wang HD, Jiang SS, Hsu JM, Jim WT, Chen M, Kung HJ, Chuu CP. PMID: 24349321; PMCID: PMC3857776.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi's sarcoma associated herpesvirus reactivation. BMC Genomics. 2013 Nov 23; 14:824.
Chang PC, Cheng CY, Campbell M, Yang YC, Hsu HW, Chang TY, Chu CH, Lee YW, Hung CL, Lai SM, Tepper CG, Hsieh WP, Wang HW, Tang CY, Wang WC, Kung HJ. PMID: 24267727; PMCID: PMC4046822.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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A lytic viral long noncoding RNA modulates the function of a latent protein. J Virol. 2014 Feb; 88(3):1843-8.
Campbell M, Kim KY, Chang PC, Huerta S, Shevchenko B, Wang DH, Izumiya C, Kung HJ, Izumiya Y. PMID: 24257619; PMCID: PMC3911622.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation. PLoS Pathog. 2013; 9(8):e1003506.
Izumiya Y, Kobayashi K, Kim KY, Pochampalli M, Izumiya C, Shevchenko B, Wang DH, Huerta SB, Martinez A, Campbell M, Kung HJ. PMID: 23990779; PMCID: PMC3749962.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. PLoS One. 2013; 8(8):e70910.
Guo W, Liu R, Bhardwaj G, Ma AH, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, Lam KS, Kung HJ. PMID: 23967135; PMCID: PMC3744530.
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PubMed Mentions:
4 Fields:
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HumansAnimalsCells
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Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a Marek's disease virus oncoprotein, Meq. J Virol. 2013 Aug; 87(16):9016-29.
Subramaniam S, Johnston J, Preeyanon L, Brown CT, Kung HJ, Cheng HH. PMID: 23740999; PMCID: PMC3754031.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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miR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT. Oncogene. 2014 May 08; 33(19):2495-503.
Kao CJ, Martiniez A, Shi XB, Yang J, Evans CP, Dobi A, deVere White RW, Kung HJ. PMID: 23728339; PMCID: PMC4370229.
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PubMed Mentions:
83 Fields:
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HumansAnimalsCells
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Quantitative analysis of autophagy using advanced 3D fluorescence microscopy. J Vis Exp. 2013 May 03; (75):e50047.
Changou CA, Wolfson DL, Ahluwalia BS, Bold RJ, Kung HJ, Chuang FY. PMID: 23665532; PMCID: PMC3670569.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A. J Virol. 2013 Jun; 87(12):6782-93.
Kim KY, Huerta SB, Izumiya C, Wang DH, Martinez A, Shevchenko B, Kung HJ, Campbell M, Izumiya Y. PMID: 23576503; PMCID: PMC3676133.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer. PLoS One. 2013; 8(4):e61064.
Amir S, Ma AH, Shi XB, Xue L, Kung HJ, Devere White RW. PMID: 23585871; PMCID: PMC3621663.
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PubMed Mentions:
43 Fields:
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HumansCells
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Microscopic analysis of cell death by metabolic stress-induced autophagy in prostate cancer. Proceedings of SPIE. 2013 Feb 22; 8587:85870d-85870d-7.
Changou CC, Cheng CR, Bold BR, Kung KH, Chuang CF. .
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Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol. 2013 Mar 10; 31(8):1039-49.
Li T, Kung HJ, Mack PC, Gandara DR. PMID: 23401433; PMCID: PMC3589700.
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PubMed Mentions:
235 Fields:
Translation:
Humans
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Tyrosine kinome profiling: oncogenic mutations and therapeutic targeting in cancer. . 2013 Jan 1; 58-75.
Ghosh GP, Qiu QY, Wang WL, Kung KH. .
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Autophagy and Prostate Cancer Therapeutics. . 2013 Jan 1; 497-518.
Kung KH, Changou CC, Nguyen NH, Yang YJ, Evans EC, Bold BR, Chuang CF. .
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Modeling truncated AR expression in a natural androgen responsive environment and identification of RHOB as a direct transcriptional target. PLoS One. 2012; 7(11):e49887.
Tsai HC, Boucher DL, Martinez A, Tepper CG, Kung HJ. PMID: 23209612; PMCID: PMC3510170.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization. Endocr Relat Cancer. 2012 Dec; 19(6):759-77.
Mooso BA, Vinall RL, Tepper CG, Savoy RM, Cheung JP, Singh S, Siddiqui S, Wang Y, Bedolla RG, Martinez A, Mudryj M, Kung HJ, Devere White RW, Ghosh PM. PMID: 22993077; PMCID: PMC3540117.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells. Oncogene. 2013 Aug 29; 32(35):4130-8.
Shi XB, Xue L, Ma AH, Tepper CG, Gandour-Edwards R, Kung HJ, deVere White RW. PMID: 23069658; PMCID: PMC4111479.
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PubMed Mentions:
86 Fields:
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HumansAnimalsCells
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Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov; 82(5):938-47.
Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. PMID: 22899868; PMCID: PMC3477223.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Mol Cell Biol. 2012 Aug; 32(15):3121-31.
Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X, Kung HJ, Gao AC, Zou JX, Chen HW. PMID: 22645312; PMCID: PMC3434505.
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PubMed Mentions:
70 Fields:
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HumansAnimalsCells
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Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544.
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, et al. PMID: 22966490; PMCID: PMC3404883.
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PubMed Mentions:
1814 Fields:
Translation:
HumansAnimals
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MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth. PLoS One. 2012; 7(3):e32832.
Nadiminty N, Tummala R, Lou W, Zhu Y, Shi XB, Zou JX, Chen H, Zhang J, Chen X, Luo J, deVere White RW, Kung HJ, Evans CP, Gao AC. PMID: 22479342; PMCID: PMC3316551.
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PubMed Mentions:
90 Fields:
Translation:
HumansAnimalsCells
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ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors. Neoplasia. 2012 Jan; 14(1):74-83.
Yamashita S, Lai KP, Chuang KL, Xu D, Miyamoto H, Tochigi T, Pang ST, Li L, Arai Y, Kung HJ, Yeh S, Chang C. PMID: 22355276; PMCID: PMC3281944.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen. J Biol Chem. 2012 Feb 17; 287(8):5806-18.
Campbell M, Chang PC, Huerta S, Izumiya C, Davis R, Tepper CG, Kim KY, Shevchenko B, Wang DH, Jung JU, Luciw PA, Kung HJ, Izumiya Y. PMID: 22179613; PMCID: PMC3285351.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
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MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. J Biol Chem. 2012 Jan 06; 287(2):1527-37.
Nadiminty N, Tummala R, Lou W, Zhu Y, Zhang J, Chen X, eVere White RW, Kung HJ, Evans CP, Gao AC. PMID: 22128178; PMCID: PMC3256915.
View in:
PubMed Mentions:
99 Fields:
Translation:
HumansCells
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Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1. Oncogene. 2012 Jun 14; 31(24):2907-18.
Wang LY, Kung HJ. PMID: 21986944; PMCID: PMC3566783.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration. Int J Cancer. 2012 Jun 01; 130(11):2693-702.
Bai L, Yang JC, Ok JH, Mack PC, Kung HJ, Evans CP. PMID: 21792888.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Ligand-independent activation of the arylhydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment. Biol Chem. 2011 Oct; 392(10):897-908.
Fujisawa Y, Li W, Wu D, Wong P, Vogel C, Dong B, Kung HJ, Matsumura F. PMID: 21861773.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Novel flavonoids with antiproliferative activities against breast cancer cells. J Med Chem. 2011 Jul 14; 54(13):4339-49.
Yao N, Chen CY, Wu CY, Motonishi K, Kung HJ, Lam KS. PMID: 21599001; PMCID: PMC3169196.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Recombinant origin of the retrovirus XMRV. Science. 2011 Jul 01; 333(6038):97-101.
Paprotka T, Delviks-Frankenberry KA, Cingöz O, Martinez A, Kung HJ, Tepper CG, Hu WS, Fivash MJ, Coffin JM, Pathak VK. PMID: 21628392; PMCID: PMC3278917.
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PubMed Mentions:
143 Fields:
Translation:
HumansAnimalsCells
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Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins. Am J Cancer Res. 2011; 1(4):542-61.
Roy M, Kung HJ, Ghosh PM. PMID: 21984972; PMCID: PMC3186052.
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PubMed Mentions:
33
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Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor. J Virol. 2011 Apr; 85(7):3283-93.
Chang PC, Fitzgerald LD, Hsia DA, Izumiya Y, Wu CY, Hsieh WP, Lin SF, Campbell M, Lam KS, Luciw PA, Tepper CG, Kung HJ. PMID: 21228229; PMCID: PMC3067885.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Targeting tyrosine kinases and autophagy in prostate cancer. Horm Cancer. 2011 Feb; 2(1):38-46.
Kung HJ. PMID: 21350583; PMCID: PMC3020299.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
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Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines. Endocr Relat Cancer. 2010 Dec; 17(4):857-73.
Chen H, Libertini SJ, George M, Dandekar S, Tepper CG, Al-Bataina B, Kung HJ, Ghosh PM, Mudryj M. PMID: 20634343; PMCID: PMC3539310.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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miR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes. Prostate. 2011 Apr; 71(5):538-49.
Shi XB, Xue L, Ma AH, Tepper CG, Kung HJ, White RW. PMID: 20886540; PMCID: PMC3017658.
View in:
PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
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Multiplex analysis of Src family kinase signaling by microbead suspension arrays. Assay Drug Dev Technol. 2010 Aug; 8(4):488-96.
Campbell M, Lie WR, Zhao J, Hayes D, Mistry J, Kung HJ, Luciw PA, Khan IH. PMID: 20482378.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Effect of the specific Src family kinase inhibitor saracatinib on osteolytic lesions using the PC-3 bone model. Mol Cancer Ther. 2010 Jun; 9(6):1629-37.
Yang JC, Bai L, Yap S, Gao AC, Kung HJ, Evans CP. PMID: 20484016.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9671-6.
Hsia DA, Tepper CG, Pochampalli MR, Hsia EY, Izumiya C, Huerta SB, Wright ME, Chen HW, Kung HJ, Izumiya Y. PMID: 20457893; PMCID: PMC2906833.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
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Aberrant activation of the androgen receptor by NF-kappaB2/p52 in prostate cancer cells. Cancer Res. 2010 Apr 15; 70(8):3309-19.
Nadiminty N, Lou W, Sun M, Chen J, Yue J, Kung HJ, Evans CP, Zhou Q, Gao AC. PMID: 20388792; PMCID: PMC3041633.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Both homo and heterodimers of Marek's disease virus encoded Meq protein contribute to transformation of lymphocytes in chickens. Virology. 2010 Apr 10; 399(2):312-21.
Suchodolski PF, Izumiya Y, Lupiani B, Ajithdoss DK, Lee LF, Kung HJ, Reddy SM. PMID: 20137800.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Microbead arrays for the analysis of ErbB receptor tyrosine kinase activation and dimerization in breast cancer cells. Assay Drug Dev Technol. 2010 Feb; 8(1):27-36.
Khan IH, Zhao J, Ghosh P, Ziman M, Sweeney C, Kung HJ, Luciw PA. PMID: 20035613; PMCID: PMC3196214.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer. 2010 Jan; 1(1):40-9.
Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, Kung HJ. PMID: 20811583; PMCID: PMC2930266.
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PubMed Mentions:
89
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Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific. J Biol Chem. 2010 Feb 19; 285(8):5266-73.
Chang PC, Izumiya Y, Wu CY, Fitzgerald LD, Campbell M, Ellison TJ, Lam KS, Luciw PA, Kung HJ. PMID: 20034935; PMCID: PMC2820755.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines. J Biol Chem. 2010 Jan 22; 285(4):2368-74.
Chen H, Libertini SJ, Wang Y, Kung HJ, Ghosh P, Mudryj M. PMID: 19946123; PMCID: PMC2807295.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Interleukin-6 regulates androgen synthesis in prostate cancer cells. Clin Cancer Res. 2009 Aug 01; 15(15):4815-22.
Chun JY, Nadiminty N, Dutt S, Lou W, Yang JC, Kung HJ, Evans CP, Gao AC. PMID: 19638459; PMCID: PMC3041150.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase. Cancer Res. 2009 Jul 15; 69(14):5681-9.
Chang PC, Fitzgerald LD, Van Geelen A, Izumiya Y, Ellison TJ, Wang DH, Ann DK, Luciw PA, Kung HJ. PMID: 19584288; PMCID: PMC2731626.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
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ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer. Autophagy. 2009 May; 5(4):567-8.
Kim RH, Bold RJ, Kung HJ. PMID: 19276647; PMCID: PMC4294541.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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The Src inhibitor AZD0530 blocks invasion and may act as a radiosensitizer in lung cancer cells. J Thorac Oncol. 2009 Apr; 4(4):448-54.
Purnell PR, Mack PC, Tepper CG, Evans CP, Green TP, Gumerlock PH, Lara PN, Gandara DR, Kung HJ, Gautschi O. PMID: 19240653; PMCID: PMC2716757.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. Cancer Res. 2009 Apr 15; 69(8):3339-46.
Zou JX, Guo L, Revenko AS, Tepper CG, Gemo AT, Kung HJ, Chen HW. PMID: 19318566.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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A comprehensive analysis of recruitment and transactivation potential of K-Rta and K-bZIP during reactivation of Kaposi's sarcoma-associated herpesvirus. Virology. 2009 Apr 25; 387(1):76-88.
Ellison TJ, Izumiya Y, Izumiya C, Luciw PA, Kung HJ. PMID: 19269659; PMCID: PMC4327937.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator. J Virol. 2009 May; 83(9):4435-46.
Izumiya Y, Izumiya C, Hsia D, Ellison TJ, Luciw PA, Kung HJ. PMID: 19244329; PMCID: PMC2668470.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009 Mar 15; 69(6):2305-13.
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. PMID: 19244107; PMCID: PMC2672822.
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PubMed Mentions:
466 Fields:
Translation:
HumansAnimalsCells
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In vitro characterization of the Meq proteins of Marek's disease virus vaccine strain CVI988. Virus Res. 2009 Jun; 142(1-2):57-67.
Ajithdoss DK, Reddy SM, Suchodolski PF, Lee LF, Kung HJ, Lupiani B. PMID: 19189855.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Res. 2009 Jan 15; 69(2):700-8.
Kim RH, Coates JM, Bowles TL, McNerney GP, Sutcliffe J, Jung JU, Gandour-Edwards R, Chuang FY, Bold RJ, Kung HJ. PMID: 19147587; PMCID: PMC2629384.
View in:
PubMed Mentions:
144 Fields:
Translation:
HumansAnimalsCells
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Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer. Cancer Res. 2009 Jan 01; 69(1):151-60.
Yang JC, Ok JH, Busby JE, Borowsky AD, Kung HJ, Evans CP. PMID: 19117998; PMCID: PMC2626435.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Oncogenic activation of androgen receptor. Urol Oncol. 2009 Jan-Feb; 27(1):48-52.
Kung HJ, Evans CP. PMID: 19111798; PMCID: PMC2629789.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Cellular and Molecular Signatures of Androgen Ablation of Prostate Cancer. . 2009 Jan 1; 507-551.
Tepper TC, Kung KH. .
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Publisher Site Mentions:
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Homodimerization of Marek's disease virus-encoded Meq protein is not sufficient for transformation of lymphocytes in chickens. J Virol. 2009 Jan; 83(2):859-69.
Suchodolski PF, Izumiya Y, Lupiani B, Ajithdoss DK, Gilad O, Lee LF, Kung HJ, Reddy SM. PMID: 18971275; PMCID: PMC2612399.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase. Int J Cancer. 2008 Oct 15; 123(8):1950-5.
Bowles TL, Kim R, Galante J, Parsons CM, Virudachalam S, Kung HJ, Bold RJ. PMID: 18661517; PMCID: PMC4294549.
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PubMed Mentions:
76 Fields:
Translation:
HumansAnimals
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RNA editing of androgen receptor gene transcripts in prostate cancer cells. J Biol Chem. 2008 Oct 31; 283(44):29938-49.
Martinez HD, Jasavala RJ, Hinkson I, Fitzgerald LD, Trimmer JS, Kung HJ, Wright ME. PMID: 18708348; PMCID: PMC2662061.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530. Oncogene. 2008 Oct 23; 27(49):6365-75.
Chang YM, Bai L, Liu S, Yang JC, Kung HJ, Evans CP. PMID: 18679417; PMCID: PMC4294546.
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PubMed Mentions:
85 Fields:
Translation:
HumansCells
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Impairment of the DNA repair and growth arrest pathways by p53R2 silencing enhances DNA damage-induced apoptosis in a p53-dependent manner in prostate cancer cells. Mol Cancer Res. 2008 May; 6(5):808-18.
Devlin HL, Mack PC, Burich RA, Gumerlock PH, Kung HJ, Mudryj M, deVere White RW. PMID: 18505925.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer. Cancer Res. 2008 Apr 01; 68(7):2250-8.
Gautschi O, Tepper CG, Purnell PR, Izumiya Y, Evans CP, Green TP, Desprez PY, Lara PN, Gandara DR, Mack PC, Kung HJ. PMID: 18381431.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Recombinant Marek's disease virus (MDV) lacking the Meq oncogene confers protection against challenge with a very virulent plus strain of MDV. Vaccine. 2008 Mar 28; 26(15):1887-92.
Lee LF, Lupiani B, Silva RF, Kung HJ, Reddy SM. PMID: 18313812.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19983-8.
Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, Tepper CG, Evans CP, Kung HJ, deVere White RW. PMID: 18056640; PMCID: PMC2148409.
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PubMed Mentions:
227 Fields:
Translation:
HumansCells
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BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer. J Cell Biochem. 2007 Dec 01; 102(5):1171-9.
Mortenson MM, Galante JG, Gilad O, Schlieman MG, Virudachalam S, Kung HJ, Bold RJ. PMID: 17960583.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res. 2007 Oct 01; 67(19):9001-5.
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. PMID: 17909000.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway. Oncogene. 2008 Jan 17; 27(4):499-505.
Liu S, Vinall RL, Tepper C, Shi XB, Xue LR, Ma AH, Wang LY, Fitzgerald LD, Wu Z, Gandour-Edwards R, deVere White RW, Kung HJ. PMID: 17653089.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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The oncogenic potential of a prostate cancer-derived androgen receptor mutant. Prostate. 2007 May 01; 67(6):591-602.
Shi XB, Xue L, Tepper CG, Gandour-Edwards R, Ghosh P, Kung HJ, DeVere White RW. PMID: 17262801.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Origin and prognostic value of circulating KRAS mutations in lung cancer patients. Cancer Lett. 2007 Sep 08; 254(2):265-73.
Gautschi O, Huegli B, Ziegler A, Gugger M, Heighway J, Ratschiller D, Mack PC, Gumerlock PH, Kung HJ, Stahel RA, Gandara DR, Betticher DC. PMID: 17449174.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Heptad repeats regulate protein phosphatase 2a recruitment to I-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax. J Biol Chem. 2007 Apr 20; 282(16):12119-26.
Hong S, Wang LC, Gao X, Kuo YL, Liu B, Merling R, Kung HJ, Shih HM, Giam CZ. PMID: 17314097.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Nonreceptor tyrosine kinases in prostate cancer. Neoplasia. 2007 Feb; 9(2):90-100.
Chang YM, Kung HJ, Evans CP. PMID: 17357254; PMCID: PMC1813931.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2. Mol Endocrinol. 2007 Mar; 21(3):613-24.
Nair SS, Guo Z, Mueller JM, Koochekpour S, Qiu Y, Tekmal RR, Schüle R, Kung HJ, Kumar R, Vadlamudi RK. PMID: 17192406; PMCID: PMC3725294.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP. J Virol. 2007 Feb; 81(3):1072-82.
Izumiya Y, Izumiya C, Van Geelen A, Wang DH, Lam KS, Luciw PA, Kung HJ. PMID: 17108053; PMCID: PMC1797516.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications. Cancer Res. 2006 Nov 01; 66(21):10449-59.
Desai SJ, Ma AH, Tepper CG, Chen HW, Kung HJ. PMID: 17079466.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genes. Prostate. 2006 Oct 01; 66(14):1474-86.
Zou JX, Zhong Z, Shi XB, Tepper CG, deVere White RW, Kung HJ, Chen H. PMID: 16921507.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Cancer Res. 2006 Sep 01; 66(17):8439-47.
Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ. PMID: 16951154.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Res. 2006 Aug 15; 66(16):8058-64.
Dai B, Kim O, Xie Y, Guo Z, Xu K, Wang B, Kong X, Melamed J, Chen H, Bieberich CJ, Borowsky AD, Kung HJ, Wei G, Ostrowski MC, Brodie A, Qiu Y. PMID: 16912182.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Multiplex analysis of intracellular signaling pathways in lymphoid cells by microbead suspension arrays. Mol Cell Proteomics. 2006 Apr; 5(4):758-68.
Khan IH, Mendoza S, Rhyne P, Ziman M, Tuscano J, Eisinger D, Kung HJ, Luciw PA. PMID: 16369048.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells. Prostate. 2005 Dec 01; 65(4):375-89.
Tepper CG, Gregg JP, Shi XB, Vinall RL, Baron CA, Ryan PE, Desprez PY, Kung HJ, deVere White RW. PMID: 16037992.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: a converging transforming pathway for avian oncoviruses. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14831-6.
Levy AM, Gilad O, Xia L, Izumiya Y, Choi J, Tsalenko A, Yakhini Z, Witter R, Lee L, Cardona CJ, Kung HJ. PMID: 16203997; PMCID: PMC1253582.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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c-Jun controls the efficiency of MAP kinase signaling by transcriptional repression of MAP kinase phosphatases. Exp Cell Res. 2005 Aug 15; 308(2):459-68.
Sprowles A, Robinson D, Wu YM, Kung HJ, Wisdom R. PMID: 15950217.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification. J Virol. 2005 Aug; 79(15):9912-25.
Izumiya Y, Ellison TJ, Yeh ET, Jung JU, Luciw PA, Kung HJ. PMID: 16014952; PMCID: PMC1181544.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus. J Virol. 2005 Jun; 79(11):6984-96.
Kamil JP, Tischer BK, Trapp S, Nair VK, Osterrieder N, Kung HJ. PMID: 15890938; PMCID: PMC1112136.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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NEUROENDOCRINE DIFFERENTIATION AND ANDROGEN-INDEPENDENCE IN PROSTATE CANCER. . 2005 Mar 1; 157-189.
Desai DS, Tepper TC, Kung KH. .
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Publisher Site Mentions:
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Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. J Biol Chem. 2005 Mar 18; 280(11):10827-33.
Mayeur GL, Kung WJ, Martinez A, Izumiya C, Chen DJ, Kung HJ. PMID: 15640154.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Negative modulation of androgen receptor transcriptional activity by Daxx. Mol Cell Biol. 2004 Dec; 24(24):10529-41.
Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, Kung HJ, Shih HM. PMID: 15572661; PMCID: PMC533990.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Signal pathways in up-regulation of chemokines by tyrosine kinase MER/NYK in prostate cancer cells. Cancer Res. 2004 Oct 15; 64(20):7311-20.
Wu YM, Robinson DR, Kung HJ. PMID: 15492251.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage. J Biol Chem. 2004 Nov 26; 279(48):50181-9.
Jiang T, Guo Z, Dai B, Kang M, Ann DK, Kung HJ, Qiu Y. PMID: 15355990.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Cocoa procyanidins inhibit proliferation and angiogenic signals in human dermal microvascular endothelial cells following stimulation by low-level H2O2. Exp Biol Med (Maywood). 2004 Sep; 229(8):765-71.
Kenny TP, Keen CL, Jones P, Kung HJ, Schmitz HH, Gershwin ME. PMID: 15337830.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication. Proc Natl Acad Sci U S A. 2004 Aug 10; 101(32):11815-20.
Lupiani B, Lee LF, Cui X, Gimeno I, Anderson A, Morgan RW, Silva RF, Witter RL, Kung HJ, Reddy SM. PMID: 15289599; PMCID: PMC511057.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Molecular alterations associated with LNCaP cell progression to androgen independence. Prostate. 2004 Aug 01; 60(3):257-71.
Shi XB, Ma AH, Tepper CG, Xia L, Gregg JP, Gandour-Edwards R, Mack PC, Kung HJ, deVere White RW. PMID: 15176055.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway. J Biol Chem. 2004 Sep 10; 279(37):38325-30.
Hamza MS, Reyes RA, Izumiya Y, Wisdom R, Kung HJ, Luciw PA. PMID: 15247271.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Marek's disease virus-encoded vIL-8 gene is involved in early cytolytic infection but dispensable for establishment of latency. J Virol. 2004 May; 78(9):4753-60.
Cui X, Lee LF, Reed WM, Kung HJ, Reddy SM. PMID: 15078957; PMCID: PMC387696.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene. 2004 Mar 18; 23(12):2197-205.
Lee LF, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, Kung HJ. PMID: 14767470.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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The role of tyrosine kinase Etk/Bmx in EGF-induced apoptosis of MDA-MB-468 breast cancer cells. Oncogene. 2004 Mar 11; 23(10):1854-62.
Chen KY, Huang LM, Kung HJ, Ann DK, Shih HM. PMID: 14676838.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Pentameric procyanidins isolated from Theobroma cacao seeds selectively downregulate ErbB2 in human aortic endothelial cells. Exp Biol Med (Maywood). 2004 Mar; 229(3):255-63.
Kenny TP, Keen CL, Jones P, Kung HJ, Schmitz HH, Gershwin ME. PMID: 14988518.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformation. Cancer Biol Ther. 2004 Jan; 3(1):96-101.
He H, Hirokawa Y, Gazit A, Yamashita Y, Mano H, Kawakami Y, Hsieh CY, Kung HJ, Lessene G, Baell J, Levitzki A, Maruta H. PMID: 14726663.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Characterization of the chromosomal binding sites and dimerization partners of the viral oncoprotein Meq in Marek's disease virus-transformed T cells. J Virol. 2003 Dec; 77(23):12841-51.
Levy AM, Izumiya Y, Brunovskis P, Xia L, Parcells MS, Reddy SM, Lee L, Chen HW, Kung HJ. PMID: 14610205; PMCID: PMC262596.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Marek's disease virus latent protein MEQ: delineation of an epitope in the BR1 domain involved in nuclear localization. Virus Genes. 2003 Dec; 27(3):211-8.
Lee LF, Liu JL, Cui XP, Kung HJ. PMID: 14618081.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as transcriptional repressors for gamma-2 herpesvirus lytic replication. Mol Cell Biol. 2003 Nov; 23(22):8282-94.
Gwack Y, Nakamura H, Lee SH, Souvlis J, Yustein JT, Gygi S, Kung HJ, Jung JU. PMID: 14585985; PMCID: PMC262387.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene. 2003 Sep 18; 22(40):6129-41.
Yustein JT, Xia L, Kahlenburg JM, Robinson D, Templeton D, Kung HJ. PMID: 13679851.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G1 growth arrest. J Virol. 2003 Sep; 77(17):9652-61.
Izumiya Y, Lin SF, Ellison TJ, Levy AM, Mayeur GL, Izumiya C, Kung HJ. PMID: 12915577; PMCID: PMC187423.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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K-bZIP of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) binds KSHV/HHV-8 Rta and represses Rta-mediated transactivation. J Virol. 2003 Mar; 77(6):3809-15.
Liao W, Tang Y, Lin SF, Kung HJ, Giam CZ. PMID: 12610155; PMCID: PMC149497.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Androgen-induced recruitment of RNA polymerase II to a nuclear receptor-p160 coactivator complex. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2226-30.
Louie MC, Yang HQ, Ma AH, Xu W, Zou JX, Kung HJ, Chen HW. PMID: 12589022; PMCID: PMC151322.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus K-bZIP is a coregulator of K-Rta: physical association and promoter-dependent transcriptional repression. J Virol. 2003 Jan; 77(2):1441-51.
Izumiya Y, Lin SF, Ellison T, Chen LY, Izumiya C, Luciw P, Kung HJ. PMID: 12502859; PMCID: PMC140808.
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PubMed Mentions:
72 Fields:
Translation:
Cells
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Angiogenesis is not mediated by prostate cancer neuropeptides. Angiogenesis. 2003; 6(4):289-93.
Busby JE, Shih SJ, Yang JC, Kung HJ, Evans CP. PMID: 15166497.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea. Oncogene. 2002 Dec 12; 21(57):8732-40.
Zhou H, Liu L, Lee K, Qin X, Grasso AW, Kung HJ, Willis JE, Kern J, Wagner T, Gerson SL. PMID: 12483526.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Elevated expression of tyrosine kinase DDR2 in primary biliary cirrhosis. Autoimmunity. 2002 Dec; 35(8):521-9.
Mao TK, Kimura Y, Kenny TP, Branchi A, Gishi RG, Van de Water J, Kung HJ, Friedman SL, Gershwin ME. PMID: 12765478.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res. 2002 Nov 15; 62(22):6606-14.
Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, Pretlow TG, Kung HJ. PMID: 12438256.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. J Biol Chem. 2002 Sep 13; 277(37):34367-74.
Huang CY, Wu YM, Hsu CY, Lee WS, Lai MD, Lu TJ, Huang CL, Leu TH, Shih HM, Fang HI, Robinson DR, Kung HJ, Yuan CJ. PMID: 12107159.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Identification of the bZIP and Rta homologues in the genome of rhesus monkey rhadinovirus. Virology. 2002 Jul 05; 298(2):181-8.
Lin SF, Robinson DR, Oh J, Jung JU, Luciw PA, Kung HJ. PMID: 12127781.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. J Biol Chem. 2002 Sep 20; 277(38):35422-33.
Xia L, Robinson D, Ma AH, Chen HC, Wu F, Qiu Y, Kung HJ. PMID: 12084720.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Elevated C-met in thymic dendritic cells of New Zealand Black mice. Dev Immunol. 2002 Mar; 9(1):29-34.
Okada T, Lian ZX, Hsu T, Naiki M, Ansari AA, Robinson D, Kung HJ, Boyd R, Gershwin ME. PMID: 12353660; PMCID: PMC2276091.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Functional analysis of 44 mutant androgen receptors from human prostate cancer. Cancer Res. 2002 Mar 01; 62(5):1496-502.
Shi XB, Ma AH, Xia L, Kung HJ, de Vere White RW. PMID: 11888926.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Molecular indications for in vivo integration of the avian leukosis virus, subgroup J-long terminal repeat into the Marek's disease virus in experimentally dually-infected chickens. Virus Genes. 2002 Mar; 24(2):173-80.
Davidson I, Borenshtain R, Kung HJ, Witter RL. PMID: 12018709.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Expression profile of tyrosine kinases in breast cancer. Clin Cancer Res. 2002 Feb; 8(2):361-7.
Meric F, Lee WP, Sahin A, Zhang H, Kung HJ, Hung MC. PMID: 11839650.
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PubMed Mentions:
62 Fields:
Translation:
Cells
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Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection. J Virol. 2001 Dec; 75(23):11298-306.
Bostik P, Wu P, Dodd GL, Villinger F, Mayne AE, Bostik V, Grimm BD, Robinson D, Kung HJ, Ansari AA. PMID: 11689610; PMCID: PMC114715.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase. Mol Cell Biol. 2001 Dec; 21(24):8385-97.
Lee LF, Guan J, Qiu Y, Kung HJ. PMID: 11713275; PMCID: PMC100003.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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MCF-10A-NeoST: a new cell system for studying cell-ECM and cell-cell interactions in breast cancer. Clin Cancer Res. 2001 Nov; 7(11):3640-8.
Zantek ND, Walker-Daniels J, Stewart J, Hansen RK, Robinson D, Miao H, Wang B, Kung HJ, Bissell MJ, Kinch MS. PMID: 11705887.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway. Oncogene. 2001 Oct 04; 20(45):6559-69.
Lin JL, Chen HC, Fang HI, Robinson D, Kung HJ, Shih HM. PMID: 11641781.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken. Proc Natl Acad Sci U S A. 2001 Jul 31; 98(16):9203-8.
Liu HC, Kung HJ, Fulton JE, Morgan RW, Cheng HH. PMID: 11470922; PMCID: PMC55398.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV. J Virol. 2001 Jun; 75(11):5159-73.
Parcells MS, Lin SF, Dienglewicz RL, Majerciak V, Robinson DR, Chen HC, Wu Z, Dubyak GR, Brunovskis P, Hunt HD, Lee LF, Kung HJ. PMID: 11333897; PMCID: PMC114921.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells. J Biol Chem. 2001 Aug 03; 276(31):29403-9.
Bagheri-Yarmand R, Mandal M, Taludker AH, Wang RA, Vadlamudi RK, Kung HJ, Kumar R. PMID: 11382770.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain. Nat Cell Biol. 2001 May; 3(5):439-44.
Chen R, Kim O, Li M, Xiong X, Guan JL, Kung HJ, Chen H, Shimizu Y, Qiu Y. PMID: 11331870.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Proteolytic activation of ETK/Bmx tyrosine kinase by caspases. J Biol Chem. 2001 May 25; 276(21):17672-8.
Wu YM, Huang CL, Kung HJ, Huang CY. PMID: 11278797.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Retroviral insertion into herpesviruses: discovery and implications. Dev Biol (Basel). 2001; 106:223-8; discussion 228-9, 253-63.
Kung HJ, Kamil J, Witter R, Davidson I. PMID: 11761235.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Hierarchical cleavage of focal adhesion kinase by caspases alters signal transduction during apoptosis of intestinal epithelial cells. Gastroenterology. 2001 Jan; 120(1):79-88.
Grossmann J, Artinger M, Grasso AW, Kung HJ, Schölmerich J, Fiocchi C, Levine AD. PMID: 11208716.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Meq: an MDV-specific bZIP transactivator with transforming properties. Curr Top Microbiol Immunol. 2001; 255:245-60.
Kung HJ, Xia L, Brunovskis P, Li D, Liu JL, Lee LF. PMID: 11217425.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases. J Biol Chem. 2000 Dec 29; 275(52):41124-32.
Jui HY, Tseng RJ, Wen X, Fang HI, Huang LM, Chen KY, Kung HJ, Ann DK, Shih HM. PMID: 11013262.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Signaling network of the Btk family kinases. Oncogene. 2000 Nov 20; 19(49):5651-61.
Qiu Y, Kung HJ. PMID: 11114746.
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PubMed Mentions:
87 Fields:
Translation:
Cells
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Tyrosine kinases and gastric cancer. Oncogene. 2000 Nov 20; 19(49):5680-9.
Lin W, Kao HW, Robinson D, Kung HJ, Wu CW, Chen HC. PMID: 11114748.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):6091-6.
Lee LF, Wu P, Sui D, Ren D, Kamil J, Kung HJ, Witter RL. PMID: 10823954; PMCID: PMC18563.
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PubMed Mentions:
75 Fields:
Translation:
Cells
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Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies. J Cell Sci. 2000 May; 113 ( Pt 9):1543-52.
Liu J, Hebert MD, Ye Y, Templeton DJ, Kung H, Matera AG. PMID: 10751146.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol. 2000 Mar; 20(6):2043-54.
Tsai YT, Su YH, Fang SS, Huang TN, Qiu Y, Jou YS, Shih HM, Kung HJ, Chen RH. PMID: 10688651; PMCID: PMC110821.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway. Oncogene. 2000 Feb 03; 19(5):710-8.
Yustein JT, Li D, Robinson D, Kung HJ. PMID: 10698516.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style. Virus Genes. 2000; 21(1-2):51-64.
Liu JL, Kung HJ. PMID: 11022789.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Kinase activation of the non-receptor tyrosine kinase Etk/BMX alone is sufficient to transactivate STAT-mediated gene expression in salivary and lung epithelial cells. J Biol Chem. 1999 Dec 31; 274(53):38204-10.
Wen X, Lin HH, Shih HM, Kung HJ, Ann DK. PMID: 10608894.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity. Mol Cell Biol. 1999 Dec; 19(12):8075-82.
Lee WP, Liao Y, Robinson D, Kung HJ, Liu ET, Hung MC. PMID: 10567533; PMCID: PMC84892.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Molecular biology of prostate carcinogenesis. Crit Rev Oncol Hematol. 1999 Dec; 32(3):197-208.
Lara PN, Kung HJ, Gumerlock PH, Meyers FJ. PMID: 10633849.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. Int J Cancer. 1999 Nov 26; 83(5):579-84.
Chen WS, Kung HJ, Yang WK, Lin Wc. PMID: 10521789.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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tie-1 protein tyrosine kinase: a novel independent prognostic marker for gastric cancer. Clin Cancer Res. 1999 Jul; 5(7):1745-51.
Lin WC, Li AF, Chi CW, Chung WW, Huang CL, Lui WY, Kung HJ, Wu CW. PMID: 10430078.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin. Oncogene. 1999 Jun 03; 18(22):3391-8.
Xue LY, Qiu Y, He J, Kung HJ, Oleinick NL. PMID: 10362360.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2. J Virol. 1999 May; 73(5):4208-19.
Liu JL, Ye Y, Qian Z, Qian Y, Templeton DJ, Lee LF, Kung HJ. PMID: 10196317; PMCID: PMC104200.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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MEQ and V-IL8: cellular genes in disguise? Acta Virol. 1999 Apr-Jun; 43(2-3):94-101.
Liu JL, Lin SF, Xia L, Brunovskis P, Li D, Davidson I, Lee LF, Kung HJ. PMID: 10696427.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Construction and characterization of a H19 epitope point mutant of MDV CVI988/Rispens strain. Acta Virol. 1999 Apr-Jun; 43(2-3):169-73.
Cui Z, Qin A, Lee LF, Wu P, Kung HJ. PMID: 10696440.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. J Virol. 1999 Mar; 73(3):1909-17.
Lin SF, Robinson DR, Miller G, Kung HJ. PMID: 9971770; PMCID: PMC104432.
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PubMed Mentions:
77 Fields:
Translation:
HumansCells
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The identification of monoclonality in human aberrant crypt foci. Cancer Res. 1999 Jan 01; 59(1):63-6.
Siu IM, Robinson DR, Schwartz S, Kung HJ, Pretlow TG, Petersen RB, Pretlow TP. PMID: 9892186.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells. Nature. 1998 May 07; 393(6680):83-5.
Qiu Y, Ravi L, Kung HJ. PMID: 9590694.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
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A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells. Cancer Res. 1998 May 01; 58(9):1920-9.
Zi X, Grasso AW, Kung HJ, Agarwal R. PMID: 9581834.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Altered expression of RET proto-oncogene product in prostatic intraepithelial neoplasia and prostate cancer. J Natl Cancer Inst. 1998 Apr 01; 90(7):519-23.
Dawson DM, Lawrence EG, MacLennan GT, Amini SB, Kung HJ, Robinson D, Resnick MI, Kursh ED, Pretlow TP, Pretlow TG. PMID: 9539247.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3644-9.
Qiu Y, Robinson D, Pretlow TG, Kung HJ. PMID: 9520419; PMCID: PMC19889.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst. 1998 Feb 04; 90(3):233-7.
Cheng L, Song SY, Pretlow TG, Abdul-Karim FW, Kung HJ, Dawson DV, Park WS, Moon YW, Tsai ML, Linehan WM, Emmert-Buck MR, Liotta LA, Zhuang Z. PMID: 9462681.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Molecular profiling of tyrosine kinases in normal and cancer cells. J Biomed Sci. 1998; 5(2):74-8.
Kung HJ, Chen HC, Robinson D. PMID: 9662065.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Digital cloning: identification of human cDNAs homologous to novel kinases through expressed sequence tag database searching. J Biomed Sci. 1998; 5(2):86-92.
Chen HC, Kung HJ, Robinson D. PMID: 9662067.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Tyrosine kinase expression profiles of chicken erythro-progenitor cells and oncogene-transformed erythroblasts. J Biomed Sci. 1998; 5(2):93-100.
Robinson D, Chen HC, Li D, Yustein JT, He F, Lin WC, Hayman MJ, Kung HJ. PMID: 9662068.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Transforming potential of the herpesvirus oncoprotein MEQ: morphological transformation, serum-independent growth, and inhibition of apoptosis. J Virol. 1998 Jan; 72(1):388-95.
Liu JL, Ye Y, Lee LF, Kung HJ. PMID: 9420237; PMCID: PMC109386.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Protein-tyrosine kinase and protein-serine/threonine kinase expression in human gastric cancer cell lines. J Biomed Sci. 1998; 5(2):101-10.
Lin JS, Lu CW, Huang CJ, Wu PF, Robinson D, Kung HJ, Chi CW, Wu CW, Yang WK, Whang-Peng JJ, Lin WC. PMID: 9662069.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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ErbB kinases and NDF signaling in human prostate cancer cells. Oncogene. 1997 Nov 27; 15(22):2705-16.
Grasso AW, Wen D, Miller CM, Rhim JS, Pretlow TG, Kung HJ. PMID: 9400997.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem J. 1997 Jun 15; 324 ( Pt 3):855-61.
Chu CT, Everiss KD, Wikstrand CJ, Batra SK, Kung HJ, Bigner DD. PMID: 9210410; PMCID: PMC1218502.
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PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Retroviral insertional mutagenesis of a herpesvirus: a Marek's disease virus mutant attenuated for oncogenicity but not for immunosuppression or in vivo replication. Avian Dis. 1997 Apr-Jun; 41(2):407-21.
Witter RL, Li D, Jones D, Lee LF, Kung HJ. PMID: 9201407.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Nucleolar and nuclear localization properties of a herpesvirus bZIP oncoprotein, MEQ. J Virol. 1997 Apr; 71(4):3188-96.
Liu JL, Lee LF, Ye Y, Qian Z, Kung HJ. PMID: 9060682; PMCID: PMC191451.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Novel DNA binding specificities of a putative herpesvirus bZIP oncoprotein. J Virol. 1996 Oct; 70(10):7161-70.
Qian Z, Brunovskis P, Lee L, Vogt PK, Kung HJ. PMID: 8794363; PMCID: PMC190769.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase. J Biol Chem. 1996 Aug 02; 271(31):18355-62.
Ling L, Templeton D, Kung HJ. PMID: 8702477.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res. 1996 Jul 01; 56(13):3042-6.
Nagabhushan M, Miller CM, Pretlow TP, Giaconia JM, Edgehouse NL, Schwartz S, Kung HJ, de Vere White RW, Gumerlock PH, Resnick MI, Amini SB, Pretlow TG. PMID: 8674060.
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PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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A tyrosine kinase profile of prostate carcinoma. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):5958-62.
Robinson D, He F, Pretlow T, Kung HJ. PMID: 8650201; PMCID: PMC39170.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone. J Virol. 1996 Apr; 70(4):2460-7.
Jones D, Brunovskis P, Witter R, Kung HJ. PMID: 8642673; PMCID: PMC190089.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Stepwise transformation of astrocytes by simian virus 40 large T antigen and epidermal growth factor receptor overexpression. Cell Growth Differ. 1996 Feb; 7(2):223-33.
Frisa PS, Walter EI, Ling L, Kung HJ, Jacobberger JW. PMID: 8822206.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol Cell Biol. 1995 Dec; 15(12):6582-92.
Ling L, Kung HJ. PMID: 8524223; PMCID: PMC230911.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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The effect of epidermal growth factor receptor (EGFR) expression on in vivo growth of rat C6 glioma cells. Leukemia. 1995 Oct; 9 Suppl 1:S106-12.
Fenstermaker RA, Capala J, Barth RF, Hujer A, Kung HJ, Kaetzel DM. PMID: 7475300.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Resistance to transformation by insertionally activated c-erbB is a dominant phenotype in fibroblasts. Virology. 1995 Sep 10; 212(1):277-83.
Carter TH, Dominguez N, Zeng L, Kung HJ. PMID: 7676646.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells. J Virol. 1995 Jul; 69(7):4037-44.
Qian Z, Brunovskis P, Rauscher F, Lee L, Kung HJ. PMID: 7769661; PMCID: PMC189137.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Identification and characterization of a Marek's disease virus gene encoding DNA polymerase. Virus Res. 1995 May; 36(2-3):269-78.
Sui D, Wu P, Kung HJ, Lee LF. PMID: 7653104.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Disease specificity of kinase domains: the src-encoded catalytic domain converts erbB into a sarcoma oncogene. Proc Natl Acad Sci U S A. 1995 Apr 25; 92(9):3928-32.
Chang CM, Shu HK, Kung HJ. PMID: 7732007; PMCID: PMC42075.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase. J Virol. 1995 Feb; 69(2):1172-80.
Chang CM, Shu HK, Ravi L, Pelley RJ, Shu H, Kung HJ. PMID: 7815495; PMCID: PMC188690.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Retrotransposition and herpesvirus evolution. Virus Genes. 1995; 11(2-3):259-70.
Brunovskis P, Kung HJ. PMID: 8828151.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain. Mol Cell Biol. 1994 Oct; 14(10):6868-78.
Shu HK, Chang CM, Ravi L, Ling L, Castellano CM, Walter E, Pelley RJ, Kung HJ. PMID: 7935404; PMCID: PMC359217.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Integration of multiple chicken retroviruses into multiple chicken herpesviruses: herpesviral gD as a common target of integration. Virology. 1994 Aug 15; 203(1):125-33.
Isfort RJ, Qian Z, Jones D, Silva RF, Witter R, Kung HJ. PMID: 8030268.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Retrovirus insertion into herpesviruses. Trends Microbiol. 1994 May; 2(5):174-7.
Isfort RJ, Witter R, Kung HJ. PMID: 8055182.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Hormonal regulation of the gene for the type C ecotropic retrovirus receptor in rat liver cells. J Virol. 1994 Mar; 68(3):1615-23.
Wu JY, Robinson D, Kung HJ, Hatzoglou M. PMID: 8107222; PMCID: PMC236619.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor. Crit Rev Oncog. 1994; 5(4):389-428.
Carter TH, Kung HJ. PMID: 7711115.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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A complete description of the EGF-receptor exon structure: implication in oncogenic activation and domain evolution. Oncogene. 1993 Nov; 8(11):2939-48.
Callaghan T, Antczak M, Flickinger T, Raines M, Myers M, Kung HJ. PMID: 8414496.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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A new defective retroviral vector system based on the Bryan strain of Rous sarcoma virus. Virology. 1993 Aug; 195(2):669-79.
Boerkoel CF, Federspiel MJ, Salter DW, Payne W, Crittenden LB, Kung HJ, Hughes SH. PMID: 8393241.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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An EGF-pseudomonas exotoxin A recombinant protein with a deletion in toxin binding domain specifically kills EGF receptor bearing cells. Protein Eng. 1993 Jun; 6(4):433-40.
Lee CH, Lee EC, Tsai ST, Kung HJ, Liu YC, Hwang J. PMID: 8332601.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Retroviral insertions into a herpesvirus are clustered at the junctions of the short repeat and short unique sequences. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):3855-9.
Jones D, Isfort R, Witter R, Kost R, Kung HJ. PMID: 8387199; PMCID: PMC46404.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Retrovirus insertion into herpesvirus: characterization of a Marek's disease virus harboring a solo LTR. Virology. 1993 Jan; 192(1):161-9.
Kost R, Jones D, Isfort R, Witter R, Kung HJ. PMID: 8390750.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Pseudomonas exotoxin A-epidermal growth factor (EGF) mutant chimeric protein as an indicator for identifying amino acid residues important in EGF-receptor interaction. J Biol Chem. 1992 Nov 25; 267(33):24034-40.
Shiah HS, Chen TY, Chang CM, Chow JT, Kung HJ, Hwang J. PMID: 1429738.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Transcriptional interaction between retroviral long terminal repeats (LTRs): mechanism of 5' LTR suppression and 3' LTR promoter activation of c-myc in avian B-cell lymphomas. J Virol. 1992 Aug; 66(8):4814-23.
Boerkoel CF, Kung HJ. PMID: 1321271; PMCID: PMC241309.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):4042-6.
Jones D, Lee L, Liu JL, Kung HJ, Tillotson JK. PMID: 1315048; PMCID: PMC525628.
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PubMed Mentions:
82 Fields:
Translation:
Cells
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Interaction between retroviral U5 RNA and the T psi C loop of the tRNA(Trp) primer is required for efficient initiation of reverse transcription. J Virol. 1992 Apr; 66(4):2464-72.
Aiyar A, Cobrinik D, Ge Z, Kung HJ, Leis J. PMID: 1548772; PMCID: PMC289042.
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PubMed Mentions:
79 Fields:
Translation:
Cells
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Retrovirus insertion into herpesvirus in vitro and in vivo. Proc Natl Acad Sci U S A. 1992 Feb 01; 89(3):991-5.
Isfort R, Jones D, Kost R, Witter R, Kung HJ. PMID: 1310544; PMCID: PMC48371.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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An alternatively processed mRNA from the avian c-erbB gene encodes a soluble, truncated form of the receptor that can block ligand-dependent transformation. Mol Cell Biol. 1992 Feb; 12(2):883-93.
Flickinger TW, Maihle NJ, Kung HJ. PMID: 1732751; PMCID: PMC364322.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Structural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells. J Virol. 1991 Dec; 65(12):6509-15.
Cui ZZ, Lee LF, Liu JL, Kung HJ. PMID: 1658357; PMCID: PMC250698.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Dissecting the activating mutations in v-erbB of avian erythroblastosis virus strain R. J Virol. 1991 Nov; 65(11):6173-80.
Shu HK, Pelley RJ, Kung HJ. PMID: 1681117; PMCID: PMC250306.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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EGF-R as a hemopoietic growth factor receptor: the c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal. Cell. 1991 Apr 05; 65(1):37-46.
Pain B, Woods CM, Saez J, Flickinger T, Raines M, Peyrol S, Moscovici C, Moscovici MG, Kung HJ, Jurdic P, et al. PMID: 1672832.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Native avian c-erbB gene expresses a secreted protein product corresponding to the ligand-binding domain of the receptor. Proc Natl Acad Sci U S A. 1991 Mar 01; 88(5):1825-9.
Maihle NJ, Flickinger TW, Raines MA, Sanders ML, Kung HJ. PMID: 1672045; PMCID: PMC51118.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Retroviral mutagenesis of cellular oncogenes: a review with insights into the mechanisms of insertional activation. Curr Top Microbiol Immunol. 1991; 171:1-25.
Kung HJ, Boerkoel C, Carter TH. PMID: 1814689.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Proc Natl Acad Sci U S A. 1990 Dec; 87(23):9103-7.
Shu HK, Pelley RJ, Kung HJ. PMID: 1979168; PMCID: PMC55112.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Epidermal growth factor receptor cytoplasmic domain mutations trigger ligand-independent transformation. Mol Cell Biol. 1990 Jun; 10(6):3048-55.
Massoglia S, Gray A, Dull TJ, Munemitsu S, Kun HJ, Schlessinger J, Ullrich A. PMID: 1971419; PMCID: PMC360669.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation. Proc Natl Acad Sci U S A. 1990 May; 87(10):3816-20.
Bjorge JD, Chan TO, Antczak M, Kung HJ, Fujita DJ. PMID: 2160078; PMCID: PMC53994.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Transformation of chicken embryo fibroblasts by direct DNA transfection of single oncogenes: comparative analyses of src, erbB, myc, and ras. J Virol. 1990 Apr; 64(4):1451-8.
Antczak M, Kung HJ. PMID: 2181153; PMCID: PMC249278.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Purification of genomic sized herpesvirus DNA using pulse-field electrophoresis. J Virol Methods. 1990 Mar; 27(3):311-7.
Isfort RJ, Robinson D, Kung HJ. PMID: 2157730.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Retroviral insertional mutagenesis: the making of a receptor-oncogene. Dev Biol Stand. 1990; 72:139-44.
Kung HJ, Pelley RJ, Shu HK, Maihle N, Raines M, Carter T, Boerkoel C, Moscovici G, Moscovici C. PMID: 2178108.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Disease tropism of c-erbB: effects of carboxyl-terminal tyrosine and internal mutations on tissue-specific transformation. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7164-8.
Pelley RJ, Maihle NJ, Boerkoel C, Shu HK, Carter TH, Moscovici C, Kung HJ. PMID: 2550929; PMCID: PMC298016.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Transient expression analysis of the reticuloendotheliosis virus long terminal repeat element. Nucleic Acids Res. 1989 Apr 25; 17(8):3199-215.
Ridgway AA, Kung HJ, Fujita DJ. PMID: 2542893; PMCID: PMC317723.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Coordinate alteration of pp60c-src abundance and c-src RNA expression in human neuroblastoma variants. Oncogene. 1989 Apr; 4(4):421-7.
Veillette A, O'Shaughnessy J, Horak ID, Israel MA, Yee D, Rosen N, Fujita DJ, Kung HJ, Biedler JL, Bolen JB. PMID: 2470006.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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C-erbB and the epidermal growth-factor receptor: a molecule with dual identity. Biochim Biophys Acta. 1989 Feb; 948(3):287-304.
Maihle NJ, Kung HJ. PMID: 2645940.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Proviral insertional activation of c-erbB: differential processing of the protein products arising from two alternate transcripts. Mol Cell Biol. 1988 Nov; 8(11):4868-76.
Maihle NJ, Raines MA, Flickinger TW, Kung HJ. PMID: 3062371; PMCID: PMC365580.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Mechanism of c-erbB transduction: newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins. J Virol. 1988 Jul; 62(7):2437-43.
Raines MA, Maihle NJ, Moscovici C, Crittenden L, Kung HJ. PMID: 2897475; PMCID: PMC253402.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Molecular characterization of three erbB transducing viruses generated during avian leukosis virus-induced erythroleukemia: extensive internal deletion near the kinase domain activates the fibrosarcoma- and hemangioma-inducing potentials of erbB. J Virol. 1988 Jul; 62(7):2444-52.
Raines MA, Maihle NJ, Moscovici C, Moscovici MG, Kung HJ. PMID: 2836624; PMCID: PMC253403.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB. J Virol. 1988 May; 62(5):1840-4.
Pelley RJ, Moscovici C, Hughes S, Kung HJ. PMID: 2833627; PMCID: PMC253246.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Identification of the gene encoding Marek's disease herpesvirus A antigen. J Virol. 1987 Aug; 61(8):2614-20.
Isfort RJ, Kung HJ, Velicer LF. PMID: 3037120; PMCID: PMC255710.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Amplification and rearrangement of the Kirsten ras oncogene in virus-transformed BALB/c 3T3 cells during malignant tumor progression. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5143-7.
Radinsky R, Kraemer PM, Raines MA, Kung HJ, Culp LA. PMID: 3474646; PMCID: PMC298810.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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B-lymphoma induction by reticuloendotheliosis virus: characterization of a mutated chicken syncytial virus provirus involved in c-myc activation. J Virol. 1987 Jul; 61(7):2084-90.
Swift RA, Boerkoel C, Ridgway A, Fujita DJ, Dodgson JB, Kung HJ. PMID: 3035210; PMCID: PMC254228.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes. Mol Cell Biol. 1987 May; 7(5):1978-83.
Tanaka A, Gibbs CP, Arthur RR, Anderson SK, Kung HJ, Fujita DJ. PMID: 3299057; PMCID: PMC365305.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Cloning of a putative chicken MHC class II alpha chain gene. Prog Clin Biol Res. 1987; 238:199-206.
Kivela J, Kung HJ, Dodgson J, Bacon L. PMID: 2885852.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
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C-myc activation in an unusual retrovirus-induced avian T-lymphoma resembling Marek's disease: proviral insertion 5' of exon one enhances the expression of an intron promoter. Oncogene Res. 1987; 2(1):81-94.
Isfort R, Witter RL, Kung HJ. PMID: 3505666.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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c-erbB activation in avian leukosis virus-induced erythroblastosis: multiple epidermal growth factor receptor mRNAs are generated by alternative RNA processing. Mol Cell Biol. 1986 Sep; 6(9):3128-33.
Goodwin RG, Rottman FM, Callaghan T, Kung HJ, Maroney PA, Nilsen TW. PMID: 3023963; PMCID: PMC367047.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Molecular characterization of Marek's disease herpesvirus B antigen. J Virol. 1986 Aug; 59(2):411-9.
Isfort RJ, Sithole I, Kung HJ, Velicer LF. PMID: 3016305; PMCID: PMC253091.
View in:
PubMed Mentions:
11 Fields:
Translation:
Cells
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Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts. J Virol. 1986 Mar; 57(3):1127-38.
Beug H, Hayman MJ, Raines MB, Kung HJ, Vennström B. PMID: 3005614; PMCID: PMC252847.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Synthesis, processing, and secretion of the Marek's disease herpesvirus A antigen glycoprotein. J Virol. 1986 Feb; 57(2):464-74.
Isfort RJ, Stringer RA, Kung HJ, Velicer LF. PMID: 3003379; PMCID: PMC252758.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells. Proc Natl Acad Sci U S A. 1985 Aug; 82(16):5360-4.
Chang CC, Trosko JE, Kung HJ, Bombick D, Matsumura F. PMID: 2991919; PMCID: PMC390568.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor. Cell. 1985 Jul; 41(3):719-26.
Nilsen TW, Maroney PA, Goodwin RG, Rottman FM, Crittenden LB, Raines MA, Kung HJ. PMID: 2988784.
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PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
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Insertional activation of c-myc by reticuloendotheliosis virus in chicken B lymphoma: nonrandom distribution and orientation of the proviruses. J Virol. 1985 Jun; 54(3):869-72.
Swift RA, Shaller E, Witter RL, Kung HJ. PMID: 2987538; PMCID: PMC254877.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src. Mol Cell Biol. 1985 May; 5(5):1122-9.
Anderson SK, Gibbs CP, Tanaka A, Kung HJ, Fujita DJ. PMID: 2582238; PMCID: PMC366830.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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In vitro transcription analysis of the viral promoter involved in c-myc activation in chicken B lymphomas: detection and mapping of two RNA initiation sites within the reticuloendotheliosis virus long terminal repeat. J Virol. 1985 Apr; 54(1):161-70.
Ridgway AA, Swift RA, Kung HJ, Fujita DJ. PMID: 2983111; PMCID: PMC254773.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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c-erbB activation in avian leukosis virus-induced erythroblastosis: clustered integration sites and the arrangement of provirus in the c-erbB alleles. Proc Natl Acad Sci U S A. 1985 Apr; 82(8):2287-91.
Raines MA, Lewis WG, Crittenden LB, Kung HJ. PMID: 2986110; PMCID: PMC397542.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus. J Virol. 1985 Jan; 53(1):19-24.
Gibbs CP, Tanaka A, Anderson SK, Radul J, Baar J, Ridgway A, Kung HJ, Fujita DJ. PMID: 2981336; PMCID: PMC254972.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Extensive homology exists between Marek disease herpesvirus and its vaccine virus, herpesvirus of turkeys. Proc Natl Acad Sci U S A. 1984 Jun; 81(11):3365-9.
Gibbs CP, Nazerian K, Velicer LF, Kung HJ. PMID: 6328512; PMCID: PMC345508.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
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Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus. Cell. 1983 Jun; 33(2):357-68.
Fung YK, Lewis WG, Crittenden LB, Kung HJ. PMID: 6305505.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A. 1983 Jan; 80(2):353-7.
Fung YK, Crittenden LB, Fadly AM, Kung HJ. PMID: 6300833; PMCID: PMC393375.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Orientation and position of avian leukosis virus DNA relative to the cellular oncogene c-myc in B-lymphoma tumors of highly susceptible 15I5 X 7(2) chickens. J Virol. 1982 Nov; 44(2):742-6.
Fung YK, Crittenden LB, Kung HJ. PMID: 6292531; PMCID: PMC256323.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Avian lymphoid leukosis virus infection and DNA integration in the preleukotic bursal tissues: a comparative study of susceptible and resistant lines. Virology. 1982 Jun; 119(2):411-21.
Fung YK, Fadly AM, Crittenden LB, Kung HJ. PMID: 6281983.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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An IgM-producing B lymphoblastoid cell line established from lymphomas induced by a non-defective reticuloendotheliosis virus. J Gen Virol. 1982 Feb; 58(Pt 2):351-60.
Nazerian K, Witter RL, Crittenden LB, Noori-Dalloii MR, Kung HJ. PMID: 6278061.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Specific integration of REV proviruses in avian bursal lymphomas. Nature. 1981 Dec 10; 294(5841):574-6.
Noori-Daloii MR, Swift RA, Kung HJ, Crittenden LB, Witter RL. PMID: 6273749.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses. Proc Natl Acad Sci U S A. 1981 Jun; 78(6):3418-22.
Fung YK, Fadly AM, Crittenden LB, Kung HJ. PMID: 6267589; PMCID: PMC319579.
View in:
PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus. J Virol. 1981 Jan; 37(1):127-38.
Kung HJ, Fung YK, Majors JE, Bishop JM, Varmus HE. PMID: 6260968; PMCID: PMC170989.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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The molecular basis of avian retrovirus-induced leukemogenesis. Haematol Blood Transfus. 1981; 26:445-51.
Kung HJ, Fung YK, Crittenden LC, Fadly A, Dube SK. PMID: 6274758.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Identification and characterization of dimeric and trimeric circular forms of avian sarcoma virus-specific DNA. Virology. 1980 Jun; 103(2):425-33.
Kung HJ, Shank PR, Bishop JM, Varmus HE. PMID: 6247823.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Structures of unintegrated and integrated forms of the deoxyribonucleic acid of ribonucleic acid tumour viruses. Biochem Soc Symp. 1979; 44:103-18.
Varmus HE, Shank PR, Hughes SH, Kung HJ, Heasley S, Majors J, Vogt PK, Bishop JM. PMID: 227397.
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Synthesis, structure, and integration of the DNA of RNA tumor viruses. Cold Spring Harb Symp Quant Biol. 1979; 43 Pt 2:851-64.
Varmus HE, Shank PR, Hughes SE, Kung HJ, Heasley S, Majors J, Vogt PK, Bishop JM. PMID: 90576.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell. 1978 Dec; 15(4):1383-95.
Shank PR, Hughes SH, Kung HJ, Majors JE, Quintrell N, Guntaka RV, Bishop JM, Varmus HE. PMID: 215324.
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187 Fields:
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AnimalsCells
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Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell. 1978 Dec; 15(4):1397-410.
Hughes SH, Shank PR, Spector DH, Kung HJ, Bishop JM, Varmus HE, Vogt PK, Breitman ML. PMID: 215325.
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144 Fields:
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Cells
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Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol. 1978 Mar 25; 120(1):55-82.
Varmus HE, Heasley S, Kung HJ, Oppermann H, Smith VC, Bishop JM, Shank PR. PMID: 205652.
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PubMed Mentions:
66 Fields:
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AnimalsCells
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Characterization of DNA complementary to nucleotide sequences adjacent to poly(A) at the 3'-terminus of the avian sarcoma virus genome. Virology. 1977 Jun 01; 79(1):183-97.
Tal J, Kung HJ, Varmus HE, Bishop JM. PMID: 194400.
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19 Fields:
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Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. Virology. 1977 Jun 01; 79(1):198-215.
Friedrich R, Kung HJ, Baker B, Varmus HE, Goodman HM, Bishop JM. PMID: 194401.
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21 Fields:
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Size, subunit composition, and secondary structure of the Friend virus genome. J Virol. 1976 Oct; 20(1):264-72.
Dube S, Kung HJ, Bender W, Davidson N, Ostertag W. PMID: 978793; PMCID: PMC354987.
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19 Fields:
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Cells
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Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis. J Mol Biol. 1976 Sep 15; 106(2):337-57.
Guntaka RV, Richards OC, Shank PR, Kung HJ, Davidson N. PMID: 185393.
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PubMed Mentions:
64 Fields:
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AnimalsCells
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RD-114, baboon, and woolly monkey viral RNA's compared in size and structure. Cell. 1976 Apr; 7(4):609-20.
Kung HJ, Hu S, Bender W, Bailey JM, Davidson N, Nicolson MO, McAllister RM. PMID: 182377.
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59 Fields:
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Structure, subunit composition, and molecular weight of RD-114 RNA. J Virol. 1975 Aug; 16(2):397-411.
Kung HJ, Bailey JM, Davidson N, Nicolson MO, McAllister RM. PMID: 168408; PMCID: PMC354678.
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38 Fields:
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AnimalsCells
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Electron microscope studies of tumor virus RNA. Cold Spring Harb Symp Quant Biol. 1975; 39 Pt 2:827-34.
Kung HJ, Bailey JM, Davidson N, Vogt PK, Nicolson MO, McAllister RM. PMID: 169036.
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26 Fields:
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Cells
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Structure and molecular length of the large subunits of RD-114 viral RNA. J Virol. 1974 Jul; 14(1):170-3.
Kung HJ, Bailey JM, Davidson N, Nicolson MO, McALLISTER RM. PMID: 4365329; PMCID: PMC355491.
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PubMed Mentions:
2 Fields:
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Cells
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An electron microscope study of Sindbis virus RNA. Cold Spring Harb Symp Quant Biol. 1974; 38:943-50.
Hsu MT, Kung HJ, Davidson N. PMID: 4598643.
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PubMed Mentions:
33 Fields:
Translation:
Cells