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Ruiwu Liu

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InstitutionUniversity of California Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss Z, Wang T, Chen X, Carney RP, Kung HJ, Duan Y, Ghosh PM, Lam KS. Targeting Galectin-1 impairs castration-resistant prostate cancer progression and invasion. Clin Cancer Res. 2018 Apr 17. PMID: 29666302.
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    2. Li J, Carney RP, Liu R, Fan J, Zhao S, Chen Y, Lam KS, Pan T. Microfluidic Print-to-Synthesis Platform for Efficient Preparation and Screening of Combinatorial Peptide Microarrays. Anal Chem. 2018 May 01; 90(9):5833-5840. PMID: 29633611.
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    3. Liu R, Li X, Xiao W, Lam KS. Corrigendum to 'Tumor-targeting peptides from combinatorial libraries' [Adv Drug Deliv Rev.110-111 (2017) 13-37]. Adv Drug Deliv Rev. 2018 Mar 09. PMID: 29530341.
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    4. Liu R, Li X, Lam KS. Combinatorial chemistry in drug discovery. Curr Opin Chem Biol. 2017 Jun; 38:117-126. PMID: 28494316.
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    5. Carney RP, Thillier Y, Kiss Z, Sahabi A, Heleno Campos JC, Knudson A, Liu R, Olivos D, Saunders M, Tian L, Lam KS. Combinatorial Library Screening with Liposomes for Discovery of Membrane Active Peptides. ACS Comb Sci. 2017 05 08; 19(5):299-307. PMID: 28378995.
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    6. Shih TC, Liu R, Fung G, Bhardwaj G, Ghosh PM, Lam KS. A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo. Mol Cancer Ther. 2017 Jul; 16(7):1212-1223. PMID: 28396365.
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    7. Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E. ITK inhibition for the targeted treatment of CTCL. J Dermatol Sci. 2017 Jul; 87(1):88-91. PMID: 28434812.
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    8. Carney RP, Hazari S, Rojalin T, Knudson A, Gao T, Tang Y, Liu R, Viitala T, Yliperttula M, Lam KS. Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides. Adv Biosyst. 2017 May; 1(5). PMID: 29911169.
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    9. Trans DJ, Bai R, Addison JB, Liu R, Hamel E, Coleman MA, Henderson PT. Synthesis of two fluorescent GTP?S molecules and their biological relevance. Nucleosides Nucleotides Nucleic Acids. 2017 Jun 03; 36(6):379-391. PMID: 28282254.
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    10. Yao W, Lay YE, Kot A, Liu R, Zhang H, Chen H, Lam K, Lane NE. Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference. Stem Cells. 2016 10; 34(10):2587-2600. PMID: 27334693.
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    11. Liu R, Li X, Xiao W, Lam KS. Tumor-targeting peptides from combinatorial libraries. Adv Drug Deliv Rev. 2017 Feb; 110-111:13-37. PMID: 27210583.
      View in: PubMed
    12. Guo S, He X, Chen Q, Yang G, Yao K, Dong P, Ye Y, Chen D, Zhang Z, Qin Z, Liu Z, Li Z, Xue Y, Zhang M, Liu R, Zhou F, Han H. The Effect of Preoperative Apolipoprotein A-I on the Prognosis of Surgical Renal Cell Carcinoma: A Retrospective Large Sample Study. Medicine (Baltimore). 2016 Mar; 95(12):e3147. PMID: 27015197; PMCID: PMC4998392.
    13. Xiao W, Li T, Bononi FC, Lac D, Kekessie IA, Liu Y, Sanchez E, Mazloom A, Ma AH, Lin J, Tran J, Yang K, Lam KS, Liu R. Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of a3 integrin-expressing human tumors. EJNMMI Res. 2016 Dec; 6(1):18. PMID: 26922417; PMCID: PMC4769701.
    14. Liu R, Shih TC, Deng X, Anwar L, Ahadi S, Kumaresan P, Lam KS. Design, synthesis, and application of OB2C combinatorial peptide and peptidomimetic libraries. Methods Mol Biol. 2015; 1248:3-22. PMID: 25616322; PMCID: PMC4625904.
    15. Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, Pan CX. Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014; 9(12):1807-20. PMID: 24628688; PMCID: PMC4167557.
    16. Yao W, Guan M, Jia J, Dai W, Lay YA, Amugongo S, Liu R, Olivos D, Saunders M, Lam KS, Nolta J, Olvera D, Ritchie RO, Lane NE. Reversing bone loss by directing mesenchymal stem cells to bone. Stem Cells. 2013 Sep; 31(9):2003-14. PMID: 23818248; PMCID: PMC3795809.
    17. Guo W, Liu R, Bhardwaj G, Ma AH, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, Lam KS, Kung HJ. CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. PLoS One. 2013; 8(8):e70910. PMID: 23967135.
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    18. Xiao W, Bononi FC, Townsend J, Li Y, Liu R, Lam KS. Immobilized OBOC combinatorial bead array to facilitate multiplicative screening. Comb Chem High Throughput Screen. 2013 Jul; 16(6):441-448. PMID: 23488896; PMCID: PMC4560360.
    19. Liu R, Wettersten HI, Park SH, Weiss RH. Small-molecule inhibitors of p21 as novel therapeutics for chemotherapy-resistant kidney cancer. Future Med Chem. 2013 Jun; 5(9):991-4. PMID: 23734682; PMCID: PMC4573579.
    20. Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y. Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin avß3. Bioorg Med Chem Lett. 2013 Jan 01; 23(1):340-5. PMID: 23164706; PMCID: PMC4570851.
    21. Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov; 82(5):938-47. PMID: 22899868; PMCID: PMC3477223.
    22. Zwingenberger AL, Kent MS, Liu R, Kukis DL, Wisner ER, DeNardo SJ, Taylor SL, Chen X, Lam KS. In-vivo biodistribution and safety of 99mTc-LLP2A-HYNIC in canine non-Hodgkin lymphoma. PLoS One. 2012; 7(4):e34404. PMID: 22545083; PMCID: PMC3335845.
    23. Guan M, Yao W, Liu R, Lam KS, Nolta J, Jia J, Panganiban B, Meng L, Zhou P, Shahnazari M, Ritchie RO, Lane NE. Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. Nat Med. 2012 Feb 05; 18(3):456-62. PMID: 22306732; PMCID: PMC3755884.
    24. Li J, Liu R, Lam KS, Jin LW, Duan Y. Alzheimer's disease drug candidates stabilize A-ß protein native structure by interacting with the hydrophobic core. Biophys J. 2011 Feb 16; 100(4):1076-82. PMID: 21320453; PMCID: PMC3037571.
    25. Kumaresan PR, Wang Y, Saunders M, Maeda Y, Liu R, Wang X, Lam KS. Rapid discovery of death ligands with one-bead-two-compound combinatorial library methods. ACS Comb Sci. 2011 May 09; 13(3):259-64. PMID: 21302937.
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    26. Xiao W, Wang Y, Lau EY, Luo J, Yao N, Shi C, Meza L, Tseng H, Maeda Y, Kumaresan P, Liu R, Lightstone FC, Takada Y, Lam KS. The use of one-bead one-compound combinatorial library technology to discover high-affinity avß3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handle. Mol Cancer Ther. 2010 Oct; 9(10):2714-23. PMID: 20858725; PMCID: PMC3571112.
    27. Townsend JB, Shaheen F, Liu R, Lam KS. Jeffamine derivatized TentaGel beads and poly(dimethylsiloxane) microbead cassettes for ultrahigh-throughput in situ releasable solution-phase cell-based screening of one-bead-one-compound combinatorial small molecule libraries. J Comb Chem. 2010 Sep 13; 12(5):700-12. PMID: 20593859; PMCID: PMC3045263.
    28. Zhu M, Baek H, Liu R, Song A, Lam K, Lau D. LAS0811: from combinatorial chemistry to activation of antioxidant response element. J Biomed Biotechnol. 2009; 2009:420194. PMID: 19794825; PMCID: PMC2753787.
    29. Denardo SJ, Liu R, Albrecht H, Natarajan A, Sutcliffe JL, Anderson C, Peng L, Ferdani R, Cherry SR, Lam KS. 111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies. J Nucl Med. 2009 Apr; 50(4):625-34. PMID: 19289419.
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    30. Carpenter RD, Andrei M, Aina OH, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin. J Med Chem. 2009 Jan 08; 52(1):14-9. PMID: 19072684; PMCID: PMC3164867.
    31. Baek HG, Liu R, Lam KS. Development of hydrogel TentaGel shell-core beads for ultrahigh throughput solution-phase screening of encoded OBOC combinatorial small molecule libraries. J Comb Chem. 2009 Jan-Feb; 11(1):91-102. PMID: 19061339; PMCID: PMC2693237.
    32. Luo J, Onofiok E, Shi C, Liu R, Lam KS. A novel hydrogel functionalized with specific peptidomimetic ligands for 2-D and 3-D cell culture. Adv Exp Med Biol. 2009; 611:19-20. PMID: 19400076.
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    33. Park SH, Wang X, Liu R, Lam KS, Weiss RH. High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers. Cancer Biol Ther. 2008 Dec; 7(12):2015-22. PMID: 18981726.
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    34. Kenyon NJ, Liu R, O'Roark EM, Huang W, Peng L, Lam KS. An alpha4beta1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice. Eur J Pharmacol. 2009 Jan 28; 603(1-3):138-46. PMID: 19103195; PMCID: PMC2646171.
    35. Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu R, Lam KS, Cheng RH, Hua DH, Voss JC, Jin LW. Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging. 2010 Oct; 31(10):1690-9. PMID: 19022536; PMCID: PMC2888733.
    36. Xiao W, Yao N, Peng L, Liu R, Lam KS. Near-infrared optical imaging in glioblastoma xenograft with ligand-targeting alpha 3 integrin. Eur J Nucl Med Mol Imaging. 2009 Jan; 36(1):94-103. PMID: 18712382; PMCID: PMC2842018.
    37. Peng L, Liu R, Andrei M, Xiao W, Lam KS. In vivo optical imaging of human lymphoma xenograft using a library-derived peptidomimetic against alpha4beta1 integrin. Mol Cancer Ther. 2008 Feb; 7(2):432-7. PMID: 18245670.
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    38. Miyamoto S, Liu R, Hung S, Wang X, Lam KS. Screening of a one bead-one compound combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cells. Anal Biochem. 2008 Mar 01; 374(1):112-20. PMID: 18023409; PMCID: PMC2770001.
    39. Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. Congo red and thioflavin-T analogs detect Abeta oligomers. J Neurochem. 2008 Jan; 104(2):457-68. PMID: 17953662.
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    40. Carpenter RD, Andrei M, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. Highly potent, water soluble benzimidazole antagonist for activated alpha 4 beta 1 integrin. J Med Chem. 2007 Nov 15; 50(23):5863-7. PMID: 17948981.
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    41. Aina OH, Liu R, Sutcliffe JL, Marik J, Pan CX, Lam KS. From combinatorial chemistry to cancer-targeting peptides. Mol Pharm. 2007 Sep-Oct; 4(5):631-51. PMID: 17880166.
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    42. Dixon SM, Milinkevich KA, Fujii J, Liu R, Yao N, Lam KS, Kurth MJ. A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. J Comb Chem. 2007 Jan-Feb; 9(1):143-57. PMID: 17206843.
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    43. Kumaresan PR, Natarajan A, Song A, Wang X, Liu R, DeNardo G, DeNardo S, Lam KS. Development of tissue plasminogen activator specific "on demand cleavable" (odc) linkers for radioimmunotherapy by screening one-bead-one-compound combinatorial peptide libraries. Bioconjug Chem. 2007 Jan-Feb; 18(1):175-82. PMID: 17226971.
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    44. Peng L, Liu R, Marik J, Wang X, Takada Y, Lam KS. Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. Nat Chem Biol. 2006 Jul; 2(7):381-9. PMID: 16767086.
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    45. Lau D, Guo L, Liu R, Marik J, Lam K. Peptide ligands targeting integrin alpha3beta1 in non-small cell lung cancer. Lung Cancer. 2006 Jun; 52(3):291-7. PMID: 16635537.
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    46. Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. J Med Chem. 2006 Apr 20; 49(8):2388-97. PMID: 16610782.
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    47. Liu R, Peng L, Han H, Lam KS. Structure-activity relationship studies of a series of peptidomimetic ligands for alpha(4) beta(1) integrin on Jurkat T-leukemia cells. Biopolymers. 2006; 84(6):595-604. PMID: 17041919.
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    48. Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, Kurth MJ. Discovery of selective aldo-keto reductase ligands--an on-bead assay strategy. Bioorg Med Chem Lett. 2005 Jun 02; 15(11):2938-42. PMID: 15911284.
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    49. Ying L, Liu R, Zhang J, Lam K, Lebrilla CB, Gervay-Hague J. A topologically segregated one-bead-one-compound combinatorial glycopeptide library for identification of lectin ligands. J Comb Chem. 2005 May-Jun; 7(3):372-84. PMID: 15877466.
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    50. Aina OH, Marik J, Liu R, Lau DH, Lam KS. Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries. Mol Cancer Ther. 2005 May; 4(5):806-13. PMID: 15897245.
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    51. Wang X, Peng L, Liu R, Gill SS, Lam KS. Partial alloc-deprotection approach for ladder synthesis of "one-bead one-compound" combinatorial libraries. J Comb Chem. 2005 Mar-Apr; 7(2):197-209. PMID: 15762747.
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    52. Mikawa M, Wang H, Guo L, Liu R, Marik J, Takada Y, Lam K, Lau D. Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells. Mol Cancer Ther. 2004 Oct; 3(10):1329-34. PMID: 15486200.
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    53. Liu R, Hsieh CY, Lam KS. New approaches in identifying drugs to inactivate oncogene products. Semin Cancer Biol. 2004 Feb; 14(1):13-21. PMID: 14757532.
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    54. Lam KS, Liu R, Miyamoto S, Lehman AL, Tuscano JM. Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research. Acc Chem Res. 2003 Jun; 36(6):370-7. PMID: 12809522.
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    55. Franz AH, Liu R, Song A, Lam KS, Lebrilla CB. High-throughput one-bead-one-compound approach to peptide-encoded combinatorial libraries: MALDI-MS analysis of single TentaGel beads. J Comb Chem. 2003 Mar-Apr; 5(2):125-37. PMID: 12625702.
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    56. Liu R, Marik J, Lam KS. Design, synthesis, screening, and decoding of encoded one-bead one-compound peptidomimetic and small molecule combinatorial libraries. Methods Enzymol. 2003; 369:271-87. PMID: 14722959.
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    57. Lam KS, Lehman AL, Song A, Doan N, Enstrom AM, Maxwell J, Liu R. Synthesis and screening of "one-bead one-compound" combinatorial peptide libraries. Methods Enzymol. 2003; 369:298-322. PMID: 14722961.
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    58. Liu R, Enstrom AM, Lam KS. Combinatorial peptide library methods for immunobiology research. Exp Hematol. 2003 Jan; 31(1):11-30. PMID: 12543103.
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    59. Liu R, Marik J, Lam KS. A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries. J Am Chem Soc. 2002 Jul 03; 124(26):7678-80. PMID: 12083920.
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