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Aijun Wang

Title(s)Associate Professor, Surgery
SchoolUniversity of California, Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer DL, Wang A. Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. FASEB J. 2019 May; 33(5):5836-5849. PMID: 30753093.
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    2. Gao K, Kumar P, Cortez-Toledo E, Hao D, Reynaga L, Rose M, Wang C, Farmer D, Nolta J, Zhou J, Zhou P, Wang A. Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells. Stem Cell Res Ther. 2019 01 22; 10(1):34. PMID: 30670078.
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    3. Zhou Z, Jiang H, Tu K, Yu W, Zhang J, Hu Z, Zhang H, Hao D, Huang P, Wang J, Wang A, Xiao Z, He C. ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma. J Exp Clin Cancer Res. 2019 Jan 15; 38(1):18. PMID: 30646949.
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    4. Hu F, Yan Y, Wang CW, Liu Y, Wang JJ, Zhou F, Zeng QH, Zhou X, Chen J, Wang AJ, Zhou JD. Article Effect and Mechanism of Ganoderma lucidum Polysaccharides on Human Fibroblasts and Skin Wound Healing in Mice. Chin J Integr Med. 2019 Mar; 25(3):203-209. PMID: 30552545.
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    5. Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Mol Cell. 2019 01 03; 73(1):7-21.e7. PMID: 30472188.
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    6. Zhu Y, Li X, Janairo RRR, Kwong G, Tsou AD, Chu JS, Wang A, Yu J, Wang D, Li S. Matrix stiffness modulates the differentiation of neural crest stem cells in vivo. J Cell Physiol. 2019 May; 234(5):7569-7578. PMID: 30368818.
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    7. Vanover M, Pivetti C, Lankford L, Kumar P, Galganski L, Kabagambe S, Keller B, Becker J, Chen YJ, Chung K, Lee C, Paxton Z, Deal B, Goodman L, Anderson J, Jensen G, Wang A, Farmer D. High density placental mesenchymal stromal cells provide neuronal preservation and improve motor function following in utero treatment of ovine myelomeningocele. J Pediatr Surg. 2019 Jan; 54(1):75-79. PMID: 30529115.
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    8. Zhang S, Rasai A, Wang Y, Xu J, Bannerman P, Erol D, Tsegaye D, Wang A, Soulika A, Zhan X, Guo F. The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord. Mol Neurobiol. 2018 Dec; 55(12):9001-9015. PMID: 29623612.
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    9. Wang Q, Chen J, Wang A, Sun L, Qian L, Zhou X, Liu Y, Tang S, Chen X, Cheng Y, Cao K, Zhou J. Differentially expressed circRNAs in melanocytes and melanoma cells and their effect on cell proliferation and invasion. Oncol Rep. 2018 Apr; 39(4):1813-1824. PMID: 29436673.
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    10. Wang D, Li LK, Dai T, Wang A, Li S. Adult Stem Cells in Vascular Remodeling. Theranostics. 2018; 8(3):815-829. PMID: 29344309.
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    11. Kumar P, Gao K, Wang C, Pivetti C, Lankford L, Farmer D, Wang A. In Utero Transplantation of Placenta-Derived Mesenchymal Stromal Cells for Potential Fetal Treatment of Hemophilia A. Cell Transplant. 2018 01; 27(1):130-139. PMID: 29562772.
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    12. Chang TY, Chen C, Lee M, Chang YC, Lu CH, Lu ST, Wang DY, Wang A, Guo CL, Cheng PL. Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. Elife. 2017 12 22; 6. PMID: 29271742.
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    13. Ryzhuk V, Zeng XX, Wang X, Melnychuk V, Lankford L, Farmer D, Wang A. Human amnion extracellular matrix derived bioactive hydrogel for cell delivery and tissue engineering. Mater Sci Eng C Mater Biol Appl. 2018 Apr 01; 85:191-202. PMID: 29407148.
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    14. Kabagambe SK, Lankford L, Kumar P, Chen YJ, Herout KT, Lee CJ, Stark RA, Farmer DL, Wang A. Isolation of myogenic progenitor cell population from human placenta: A pilot study. J Pediatr Surg. 2017 Dec; 52(12):2078-2082. PMID: 28964407.
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    15. Liao JL, Chen J, He B, Chen Y, Xu JQ, Xie HJ, Hu F, Wang AJ, Luo C, Li QF, Zhou JD. Viability and Biomechanics of Diced Cartilage Blended With Platelet-Rich Plasma and Wrapped With Poly (Lactic-Co-Glycolic) Acid Membrane. J Craniofac Surg. 2017 Sep; 28(6):1418-1424. PMID: 28692513.
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    16. Henry JJD, Yu J, Wang A, Lee R, Fang J, Li S. Engineering the mechanical and biological properties of nanofibrous vascular grafts for in situ vascular tissue engineering. Biofabrication. 2017 Aug 17; 9(3):035007. PMID: 28817384.
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    17. Wang D, Wu F, Yuan H, Wang A, Kang GJ, Truong T, Chen L, McCallion AS, Gong X, Li S. Sox10+ Cells Contribute to Vascular Development in Multiple Organs-Brief Report. Arterioscler Thromb Vasc Biol. 2017 09; 37(9):1727-1731. PMID: 28751573.
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    18. Long C, Lankford L, Kumar P, Grahn R, Borjesson DL, Farmer D, Wang A. Isolation and characterization of canine placenta-derived mesenchymal stromal cells for the treatment of neurological disorders in dogs. Cytometry A. 2018 01; 93(1):82-92. PMID: 28715613.
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    19. Vanover M, Wang A, Farmer D. Potential clinical applications of placental stem cells for use in fetal therapy of birth defects. Placenta. 2017 Nov; 59:107-112. PMID: 28651900.
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    20. Lankford L, Chen YJ, Saenz Z, Kumar P, Long C, Farmer D, Wang A. Manufacture and preparation of human placenta-derived mesenchymal stromal cells for local tissue delivery. Cytotherapy. 2017 06; 19(6):680-688. PMID: 28438482.
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    21. Chen YJ, Lankford L, Kabagambe S, Saenz Z, Kumar P, Farmer D, Wang A. Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix. Placenta. 2017 Nov; 59:163-168. PMID: 28465002.
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    22. Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 04 21; 12(4):1075-1086. PMID: 28195700.
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    23. Harding A, Cortez-Toledo E, Magner NL, Beegle JR, Coleal-Bergum DP, Hao D, Wang A, Nolta JA, Zhou P. Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways. Stem Cells. 2017 04; 35(4):909-919. PMID: 28248004.
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    24. Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, Huang WC, Xu K, Gong X, Li S. Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep. 2017 01 10; 7:40295. PMID: 28071739.
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    25. Li Y, Li L, Li Z, Sheng J, Zhang X, Feng D, Zhang X, Yin F, Wang A, Wang F. Tat PTD-Endostatin-RGD: A novel protein with anti-angiogenesis effect in retina via eye drops. Biochim Biophys Acta. 2016 10; 1860(10):2137-47. PMID: 27233450.
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    26. Chen L, Ao Q, Sharma HS, Wang A, Feng S. Neurorestoratologic Strategies and Mechanisms in the Nervous System. Biomed Res Int. 2015; 2015:163170. PMID: 26491655.
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    27. Brown EG, Keller BA, Lankford L, Pivetti CD, Hirose S, Farmer DL, Wang A. Age Does Matter: A Pilot Comparison of Placenta-Derived Stromal Cells for in utero Repair of Myelomeningocele Using a Lamb Model. Fetal Diagn Ther. 2016; 39(3):179-85. PMID: 26159889.
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    28. Yu M, Sun ZJ, Li LT, Ge HY, Song CQ, Wang AJ. The beneficial effects of the herbal medicine Di-huang-yin-zi (DHYZ) on patients with ischemic stroke: A Randomized, Placebo controlled clinical study. Complement Ther Med. 2015 Aug; 23(4):591-7. PMID: 26275652.
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    29. Wang A, Brown EG, Lankford L, Keller BA, Pivetti CD, Sitkin NA, Beattie MS, Bresnahan JC, Farmer DL. Placental mesenchymal stromal cells rescue ambulation in ovine myelomeningocele. Stem Cells Transl Med. 2015 Jun; 4(6):659-69. PMID: 25911465.
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    30. Brown EG, Keller BA, Pivetti CD, Sitkin NA, Wang A, Farmer DL, Bresnahan JC. Development of a locomotor rating scale for testing motor function in sheep. J Pediatr Surg. 2015 Apr; 50(4):617-21. PMID: 25840074.
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    31. Xiang P, Wu KC, Zhu Y, Xiang L, Li C, Chen DL, Chen F, Xu G, Wang A, Li M, Jin ZB. A novel Bruch's membrane-mimetic electrospun substrate scaffold for human retinal pigment epithelium cells. Biomaterials. 2014 Dec; 35(37):9777-9788. PMID: 25220295.
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    32. Wei Y, Gong K, Ao Q, Wang A, Gong Y, Zuo H, Zhang Y, Wang J, Wang G. Lentiviral vectors enveloped with rabies virus glycoprotein can be used as a novel retrograde tracer to assess nerve recovery in rat sciatic nerve injury models. Cell Tissue Res. 2014 Feb; 355(2):255-66. PMID: 24326614.
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    33. Brown EG, Saadai P, Pivetti CD, Beattie MS, Bresnahan JC, Wang A, Farmer DL. In utero repair of myelomeningocele with autologous amniotic membrane in the fetal lamb model. J Pediatr Surg. 2014 Jan; 49(1):133-7; discussion 137-8. PMID: 24439597.
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    34. Xu W, Wang Y, Liu E, Sun Y, Luo Z, Xu Z, Liu W, Zhong L, Lv Y, Wang A, Tang Z, Li S, Yang L. Human iPSC-derived neural crest stem cells promote tendon repair in a rat patellar tendon window defect model. Tissue Eng Part A. 2013 Nov; 19(21-22):2439-51. PMID: 23815150.
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    35. Lee BL, Tang Z, Wang A, Huang F, Yan Z, Wang D, Chu JS, Dixit N, Yang L, Li S. Synovial stem cells and their responses to the porosity of microfibrous scaffold. Acta Biomater. 2013 Jul; 9(7):7264-75. PMID: 23523935.
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    36. Saadai P, Wang A, Nout YS, Downing TL, Lofberg K, Beattie MS, Bresnahan JC, Li S, Farmer DL. Human induced pluripotent stem cell-derived neural crest stem cells integrate into the injured spinal cord in the fetal lamb model of myelomeningocele. J Pediatr Surg. 2013 Jan; 48(1):158-63. PMID: 23331809.
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    37. Tang Z, Wang A, Wang D, Li S. Smooth muscle cells: to be or not to be? Response to Nguyen et Al. Circ Res. 2013 Jan 04; 112(1):23-6. PMID: 23093574.
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    38. Yu J, Wang A, Tang Z, Henry J, Li-Ping Lee B, Zhu Y, Yuan F, Huang F, Li S. The effect of stromal cell-derived factor-1a/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. Biomaterials. 2012 Nov; 33(32):8062-74. PMID: 22884813.
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    39. Tang Z, Wang A, Yuan F, Yan Z, Liu B, Chu JS, Helms JA, Li S. Differentiation of multipotent vascular stem cells contributes to vascular diseases. Nat Commun. 2012 Jun 06; 3:875. PMID: 22673902.
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    40. Downing TL, Wang A, Yan ZQ, Nout Y, Lee AL, Beattie MS, Bresnahan JC, Farmer DL, Li S. Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair. J Control Release. 2012 Aug 10; 161(3):910-7. PMID: 22634093.
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    41. Lee BL, Jeon H, Wang A, Yan Z, Yu J, Grigoropoulos C, Li S. Femtosecond laser ablation enhances cell infiltration into three-dimensional electrospun scaffolds. Acta Biomater. 2012 Jul; 8(7):2648-58. PMID: 22522128.
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    42. Saadai P, Nout YS, Encinas J, Wang A, Downing TL, Beattie MS, Bresnahan JC, Li S, Farmer DL. Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds-a pilot study in sheep. J Pediatr Surg. 2011 Dec; 46(12):2279-83. PMID: 22152865.
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    43. Wang A, Tang Z, Li X, Jiang Y, Tsou DA, Li S. Derivation of smooth muscle cells with neural crest origin from human induced pluripotent stem cells. Cells Tissues Organs. 2012; 195(1-2):5-14. PMID: 22005509.
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    44. Li X, Chu J, Wang A, Zhu Y, Chu WK, Yang L, Li S. Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces. PLoS One. 2011; 6(10):e26029. PMID: 22016804.
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    45. Wei Y, Gong K, Zheng Z, Wang A, Ao Q, Gong Y, Zhang X. Chitosan/silk fibroin-based tissue-engineered graft seeded with adipose-derived stem cells enhances nerve regeneration in a rat model. J Mater Sci Mater Med. 2011 Aug; 22(8):1947-64. PMID: 21656031.
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    46. Park JS, Chu JS, Tsou AD, Diop R, Tang Z, Wang A, Li S. The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-ß. Biomaterials. 2011 Jun; 32(16):3921-30. PMID: 21397942.
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    47. Wang A, Tang Z, Park IH, Zhu Y, Patel S, Daley GQ, Li S. Induced pluripotent stem cells for neural tissue engineering. Biomaterials. 2011 Aug; 32(22):5023-32. PMID: 21514663.
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    48. Zhu Y, Wang A, Patel S, Kurpinski K, Diao E, Bao X, Kwong G, Young WL, Li S. Engineering bi-layer nanofibrous conduits for peripheral nerve regeneration. Tissue Eng Part C Methods. 2011 Jul; 17(7):705-15. PMID: 21501089.
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    49. Wei Y, Gong K, Zheng Z, Liu L, Wang A, Zhang L, Ao Q, Gong Y, Zhang X. Schwann-like cell differentiation of rat adipose-derived stem cells by indirect co-culture with Schwann cells in vitro. Cell Prolif. 2010 Dec; 43(6):606-16. PMID: 21039999.
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    50. Lam HJ, Patel S, Wang A, Chu J, Li S. In vitro regulation of neural differentiation and axon growth by growth factors and bioactive nanofibers. Tissue Eng Part A. 2010 Aug; 16(8):2641-8. PMID: 20367289.
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    51. Wang G, Ao Q, Gong K, Wang A, Zheng L, Gong Y, Zhang X. The effect of topology of chitosan biomaterials on the differentiation and proliferation of neural stem cells. Acta Biomater. 2010 Sep; 6(9):3630-9. PMID: 20371303.
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    52. Kurpinski K, Lam H, Chu J, Wang A, Kim A, Tsay E, Agrawal S, Schaffer DV, Li S. Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells. Stem Cells. 2010 Apr; 28(4):734-42. PMID: 20146266.
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    53. Wei Y, Zhou J, Zheng Z, Wang A, Ao Q, Gong Y, Zhang X. An improved method for isolating Schwann cells from postnatal rat sciatic nerves. Cell Tissue Res. 2009 Sep; 337(3):361-9. PMID: 19639342.
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    54. Zheng Z, Zhang L, Kong L, Wang A, Gong Y, Zhang X. The behavior of MC3T3-E1 cells on chitosan/poly-L-lysine composite films: effect of nanotopography, surface chemistry, and wettability. J Biomed Mater Res A. 2009 May; 89(2):453-65. PMID: 18431777.
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    55. Zhou F, Zhang L, Wang A, Song B, Gong K, Zhang L, Hu M, Zhang X, Zhao N, Gong Y. The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation. J Biol Chem. 2008 May 23; 283(21):14506-15. PMID: 18367454.
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    56. Zhou F, Zhang L, Gong K, Lu G, Sheng B, Wang A, Zhao N, Zhang X, Gong Y. LEF-1 activates the transcription of E2F1. Biochem Biophys Res Commun. 2008 Jan 04; 365(1):149-53. PMID: 17980157.
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    57. Wang A, Ao Q, Wei Y, Gong K, Liu X, Zhao N, Gong Y, Zhang X. Physical properties and biocompatibility of a porous chitosan-based fiber-reinforced conduit for nerve regeneration. Biotechnol Lett. 2007 Nov; 29(11):1697-702. PMID: 17628751.
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    58. Ao Q, Wang AJ, Chen GQ, Wang SJ, Zuo HC, Zhang XF. Combined transplantation of neural stem cells and olfactory ensheathing cells for the repair of spinal cord injuries. Med Hypotheses. 2007; 69(6):1234-7. PMID: 17548168.
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    59. Kong L, Ao Q, Wang A, Gong K, Wang X, Lu G, Gong Y, Zhao N, Zhang X. Preparation and characterization of a multilayer biomimetic scaffold for bone tissue engineering. J Biomater Appl. 2007 Nov; 22(3):223-39. PMID: 17255157.
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    60. Wang A, Ao Q, Cao W, Yu M, He Q, Kong L, Zhang L, Gong Y, Zhang X. Porous chitosan tubular scaffolds with knitted outer wall and controllable inner structure for nerve tissue engineering. J Biomed Mater Res A. 2006 Oct; 79(1):36-46. PMID: 16758450.
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    61. Qi H, Hu P, Xu J, Wang A. Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment. Biomacromolecules. 2006 Aug; 7(8):2327-30. PMID: 16903678.
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    62. Zhang L, Ao Q, Wang A, Lu G, Kong L, Gong Y, Zhao N, Zhang X. A sandwich tubular scaffold derived from chitosan for blood vessel tissue engineering. J Biomed Mater Res A. 2006 May; 77(2):277-84. PMID: 16400655.
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    63. Ao Q, Wang A, Cao W, Zhang L, Kong L, He Q, Gong Y, Zhang X. Manufacture of multimicrotubule chitosan nerve conduits with novel molds and characterization in vitro. J Biomed Mater Res A. 2006 Apr; 77(1):11-8. PMID: 16345091.
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    64. Ao Q, Sun XH, Wang AJ, Fu PF, Gong K, Zuo HC, Zuo HZ, Gong YD, Zhang XF. Protective effects of extract of Ginkgo biloba (EGb 761) on nerve cells after spinal cord injury in rats. Spinal Cord. 2006 Nov; 44(11):662-7. PMID: 16415923.
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    65. Cao W, Wang A, Jing D, Gong Y, Zhao N, Zhang X. Novel biodegradable films and scaffolds of chitosan blended with poly(3-hydroxybutyrate). J Biomater Sci Polym Ed. 2005; 16(11):1379-94. PMID: 16370239.
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