Aijun Wang

Title(s)Professor and Vice Chair, Surgery
SchoolSchool of Medicine
CA 95817
ORCID ORCID Icon0000-0002-2985-3627 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    University of California Berkeley2011Venture Lab Competition, Center for Entrepreneurship and Technology (CET)
    California Institute for Quantitative Biosciences (QB3)2012Deloitte QB3 Award for Innovation
    Children’s Miracle Network (CMN)2014Tony Philips Research Award
    American Society of Hematology (ASH)2014Best of ASH
    Marquis2015Who’s Who in America 2015
    March of Dimes Foundation2016The Basil O’Connor Starter Scholar Research Award
    University of California Center for Accelerated Innovation (UC-CAI)2017NIH/NHLBI Technology Development Award
    University of California Davis School of Medicine2018Deans Fellowship in Entrepreneurship
    University of California Davis2019Chancellor’s Fellow
    the American Society of Nephrology (ASN) and the Department of Health and Human Services (HHS)2020KidneyX: Redesign Dialysis Phase 2 Award

    Collapse Overview 
    Collapse Overview
    Dr. Aijun Wang is a Chancellor's Fellow, Professor of Surgery and Biomedical Engineering, ViceChair for Translational Research, Innovation and Entrepreneurship, and Co-Director of the Center for Surgical Bioengineering (CSB) at the Department of Surgery at the University of California Davis (UCD) School of Medicine. Dr. Wang's research focuses on developing tools, technologies and products that combine molecular, cellular, tissue and biomaterial engineering to promote regeneration and restore function. Specifically, the focus at CSB is on engineering and developing stem cell/gene therapy, extracellular vesicles/nanomedicine, and extracellular matrix/biomaterial scaffolds for the treatment of surgical conditions and diseases. Dr. Wang and his team at CSB specialize in bringing therapeutics from bench to bedside, through translational and IND-enabling studies, GMP manufacturing, and conducting clinical trials in both human and companion animal patients.
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    Engineered neuroprotective stem-cell exosomes for in utero spina bifida therapy
    NIH R01NS115860Sep 30, 2020 - Aug 31, 2025
    Role: PI
    Description: The goal of this project is to develop a new vascular graft with the potential for rapid endothelization and improved graft patency.
    Validation of Transabdominal Fetal Pulse Oximetry in Hypoxic Fetal Lamb Models
    NIH R21HD097467Jul 15, 2020 - Jun 30, 2022
    Role: Co-Investigator
    Fetal Tissue Engineering to Treat Spina Bifida Before Birth
    NIH R01NS100761Aug 1, 2017 - Apr 30, 2022
    Role: Principal Investigator
    Guinea pigs as a model of in utero stem cell therapy for spina bifida
    NIH R03HD091601Jul 1, 2017 - Jun 30, 2020
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evolution and Variations of the Ovine Model of Spina Bifida. Fetal Diagn Ther. 2023; 50(6):491-500. Lee SY, Du Y, Hassan AS, Brown E, Saadai P, Hirose S, Wang A, Farmer DL. PMID: 37393899; PMCID: PMC10757987.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. Bioact Mater. 2023 Oct; 28:467-479. Hao D, Lin J, Liu R, Pivetti C, Yamashiro K, Schutzman LM, Sageshima J, Kwong M, Bahatyrevich N, Farmer DL, Humphries MD, Lam KS, Panitch A, Wang A. PMID: 37408799; PMCID: PMC10318457.
      View in: PubMed   Mentions:
    3. Protocol for vision transformer-based evaluation of drug potency using images processed by an optimized Sobel operator. STAR Protoc. 2023 May 01; 4(2):102259. Wang Y, Zhang W, Wu Y, Qu C, Hu H, Lee T, Lin S, Zhang J, Lam KS, Wang A. PMID: 37133992; PMCID: PMC10176075.
      View in: PubMed   Mentions:    Fields:    
    4. Role of MEF2C in the Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. Stem Cells. 2023 04 25; 41(4):341-353. Li T, Conroy KL, Kim AM, Halmai J, Gao K, Moreno E, Wang A, Passerini AG, Nolta JA, Zhou P. PMID: 36639926; PMCID: PMC10128960.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. Front Pharmacol. 2023; 14:1125209. Song H, Gao K, Hao D, Li A, Liu R, Anggito B, Yin B, Jin Q, Dartora V, Lam KS, Smith LR, Panitch A, Zhou J, Farmer DL, Wang A. PMID: 36937891; PMCID: PMC10014525.
      View in: PubMed   Mentions: 2  
    6. Convergence of human and veterinary medicine: leveraging canine naturally occurring neurological disorders to develop regenerative treatments. Neural Regen Res. 2023 Mar; 18(3):541-542. Clark KC, Amador A, Wang A. PMID: 36018168; PMCID: PMC9727421.
      View in: PubMed   Mentions: 1  
    7. Challenges and strategies: Scalable and efficient production of mesenchymal stem cells-derived exosomes for cell-free therapy. Life Sci. 2023 Apr 15; 319:121524. Pan W, Chen H, Wang A, Wang F, Zhang X. PMID: 36828131.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    8. In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles. Bioact Mater. 2023 Jul; 25:387-398. Gao K, Li J, Song H, Han H, Wang Y, Yin B, Farmer DL, Murthy N, Wang A. PMID: 36844366; PMCID: PMC9950423.
      View in: PubMed   Mentions: 6  
    9. Molecular Basis of Surgical Coaptation Techniques in Peripheral Nerve Injuries. J Clin Med. 2023 Feb 16; 12(4). Pereira CT, Hill EE, Stasyuk A, Parikh N, Dhillon J, Wang A, Li A. PMID: 36836090; PMCID: PMC9966153.
      View in: PubMed   Mentions:
    10. Evaluation of a biodegradable polyurethane patch for repair of diaphragmatic hernia in a rat model: A pilot study. J Pediatr Surg. 2023 May; 58(5):964-970. Theodorou CM, Taylor A, Lee SY, Cortez LM, Fu H, Pivetti CD, Zhang C, Stasyuk A, Hao D, Kumar P, Farmer DL, Liao J, Brown EG, Hong Y, Wang A. PMID: 36797111; PMCID: PMC10184880.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. Development and Characterization of Bioinspired Lipid Raft Nanovesicles for Therapeutic Applications. ACS Appl Mater Interfaces. 2022 Dec 14; 14(49):54458-54477. Ramasubramanian L, Jyothi H, Goldbloom-Helzner L, Light BM, Kumar P, Carney RP, Farmer DL, Wang A. PMID: 36448709; PMCID: PMC9756296.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. Theranostics. 2022; 12(13):6021-6037. Hao D, Lu L, Song H, Duan Y, Chen J, Carney R, Li JJ, Zhou P, Nolta J, Lam KS, Leach JK, Farmer DL, Panitch A, Wang A. PMID: 35966577; PMCID: PMC9373818.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. Bioengineering Extracellular Vesicles for the Treatment of Cardiovascular Diseases. Adv Biol (Weinh). 2022 10; 6(10):e2200087. Ramasubramanian L, Du S, Gidda S, Bahatyrevich N, Hao D, Kumar P, Wang A. PMID: 35778828; PMCID: PMC9588622.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies. J Dev Biol. 2022 Jun 06; 10(2). Hassan AS, Du YL, Lee SY, Wang A, Farmer DL. PMID: 35735913; PMCID: PMC9224552.
      View in: PubMed   Mentions: 6  
    15. A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. Bioact Mater. 2023 Feb; 20:179-193. Hao D, Liu R, Fernandez TG, Pivetti C, Jackson JE, Kulubya ES, Jiang HJ, Ju HY, Liu WL, Panitch A, Lam KS, Leach JK, Farmer DL, Wang A. PMID: 35663336; PMCID: PMC9160290.
      View in: PubMed   Mentions: 4  
    16. Engineering Extracellular Microenvironment for Tissue Regeneration. Bioengineering (Basel). 2022 May 08; 9(5). Hao D, Lopez JM, Chen J, Iavorovschi AM, Lelivelt NM, Wang A. PMID: 35621480; PMCID: PMC9137730.
      View in: PubMed   Mentions: 6  
    17. A bioactive compliant vascular graft modulates macrophage polarization and maintains patency with robust vascular remodeling. Bioact Mater. 2023 Jan; 19:167-178. Stahl A, Hao D, Barrera J, Henn D, Lin S, Moeinzadeh S, Kim S, Maloney W, Gurtner G, Wang A, Yang YP. PMID: 35510174; PMCID: PMC9034314.
      View in: PubMed   Mentions: 7  
    18. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511. Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    19. Genetic and Molecular Determinants of Lymphatic Malformations: Potential Targets for Therapy. J Dev Biol. 2022 Feb 08; 10(1). Lee SY, Loll EG, Hassan AS, Cheng M, Wang A, Farmer DL. PMID: 35225964; PMCID: PMC8883961.
      View in: PubMed   Mentions: 4  
    20. Impact of Gestational Age on Neuroprotective Function of Placenta-Derived Mesenchymal Stromal Cells. J Surg Res. 2022 05; 273:201-210. Stokes SC, Kabagambe SK, Lee CJ, Wang A, Farmer DL, Kumar P. PMID: 35093836; PMCID: PMC9396930.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair. J Pediatr Surg. 2022 May; 57(5):941-948. Theodorou CM, Jackson JE, Stokes SC, Pivetti CD, Kumar P, Paxton ZJ, Matsukuma KE, Yamashiro KJ, Reynaga L, Hyllen AA, de Lorimier AJ, Hassan M, Wang A, Farmer DL, Saadai P. PMID: 35093254; PMCID: PMC10372624.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. The Molecular Mechanisms Through Which Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration. Adv Biol (Weinh). 2022 02; 6(2):e2101099. Clark KC, Wang D, Kumar P, Mor S, Kulubya E, Lazar SV, Wang A. PMID: 35023637; PMCID: PMC9225676.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. In Vitro, In Vivo and Ex Vivo Models for Peripheral Nerve Injury and Regeneration. Curr Neuropharmacol. 2022; 20(2):344-361. Li A, Pereira C, Hill EE, Vukcevich O, Wang A. PMID: 33827409; PMCID: PMC9413794.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. The Unique Properties of Placental Mesenchymal Stromal Cells: A Novel Source of Therapy for Congenital and Acquired Spinal Cord Injury. Cells. 2021 10 22; 10(11). Kulubya ES, Clark K, Hao D, Lazar S, Ghaffari-Rafi A, Karnati T, Ebinu JO, Zwienenberg M, Farmer DL, Wang A. PMID: 34831060; PMCID: PMC8616037.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    25. Engineering extracellular vesicles for Alzheimer's disease: An emerging cell-free approach for earlier diagnosis and treatment. WIREs Mech Dis. 2022 03; 14(2):e1541. Lazar SV, Mor S, Wang D, Goldbloom-Helzner L, Clark K, Hao D, Farmer DL, Wang A. PMID: 35266650; PMCID: PMC9397584.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Engineering Extracellular Vesicles Enriched with Palmitoylated ACE2 as COVID-19 Therapy. Adv Mater. 2021 Dec; 33(49):e2103471. Xie F, Su P, Pan T, Zhou X, Li H, Huang H, Wang A, Wang F, Huang J, Yan H, Zeng L, Zhang L, Zhou F. PMID: 34665481; PMCID: PMC8646473.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    27. Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. J Pediatr Surg. 2022 Jan; 57(1):18-25. Stokes SC, Theodorou CM, Jackson JE, Pivetti C, Kumar P, Yamashiro KJ, Paxton ZJ, Reynaga L, Hyllen A, Wang A, Farmer DL. PMID: 34657738; PMCID: PMC9415987.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    28. Fabrication and evaluation of an optimized xenogenic decellularized costal cartilage graft: preclinical studies of a novel biocompatible prosthesis for rhinoplasty. Regen Biomater. 2021 Oct; 8(6):rbab052. Lin S, He Y, Tao M, Wang A, Ao Q. PMID: 34584748; PMCID: PMC8473975.
      View in: PubMed   Mentions: 3  
    29. Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing. Bioact Mater. 2022 Apr; 10:460-473. He S, Walimbe T, Chen H, Gao K, Kumar P, Wei Y, Hao D, Liu R, Farmer DL, Lam KS, Zhou J, Panitch A, Wang A. PMID: 34901560; PMCID: PMC8636679.
      View in: PubMed   Mentions: 11  
    30. Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers. J Nanobiotechnology. 2021 Aug 21; 19(1):250. Mizenko RR, Brostoff T, Rojalin T, Koster HJ, Swindell HS, Leiserowitz GS, Wang A, Carney RP. PMID: 34419056; PMCID: PMC8379740.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    31. Preliminary Evaluation of a Novel Fetal Guinea Pig Myelomeningocele Model. Biomed Res Int. 2021; 2021:2180883. Stokes SC, Yamashiro KJ, Vanover MA, Galganski LA, Jackson JE, Theodorou CM, Pivetti CD, Farmer DL, Wang A. PMID: 34423032; PMCID: PMC8378975.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    32. Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection. World J Stem Cells. 2021 Jul 26; 13(7):776-794. Nasirishargh A, Kumar P, Ramasubramanian L, Clark K, Hao D, Lazar SV, Wang A. PMID: 34367477; PMCID: PMC8316862.
      View in: PubMed   Mentions: 19  
    33. Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. J Surg Res. 2021 11; 267:660-668. Jackson JE, Pivetti C, Stokes SC, Theodorou CM, Kumar P, Paxton ZJ, Hyllen A, Reynaga L, Wang A, Farmer DL. PMID: 34273796; PMCID: PMC9365330.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    34. Proangiogenic Collagen-Binding Glycan Therapeutic Promotes Endothelial Cell Angiogenesis. ACS Biomater Sci Eng. 2021 07 12; 7(7):3281-3292. Walimbe T, Dehghani T, Casella A, Lin J, Wang A, Panitch A. PMID: 34192455.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    35. Bioengineered extracellular vesicle-loaded bioscaffolds for therapeutic applications in regenerative medicine. Extracell Vesicles Circ Nucl Acids. 2021; 2:175-178. Lazar S, Mor S, Chen J, Hao D, Wang A. PMID: 34622248; PMCID: PMC8494210.
      View in: PubMed   Mentions: 8  
    36. Identification of differentially expressed proteins involved in fetal scarless wound healing using a rat model of cleft lip. Mol Med Rep. 2021 Aug; 24(2). Yan Y, Liu H, Yi J, Chen Z, Chen J, Zhang J, Gao K, He S, Wang A, Jin P, Hu F, Zhou J. PMID: 34165164; PMCID: PMC8240453.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    37. A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. Fetal Diagn Ther. 2021; 48(6):472-478. Stokes SC, Jackson JE, Theodorou CM, Pivetti CD, Kumar P, Yamashiro KJ, Wang A, Farmer DL. PMID: 34111873; PMCID: PMC9470811.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    38. Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. J Pediatr Surg. 2022 Apr; 57(4):753-758. Theodorou CM, Stokes SC, Jackson JE, Pivetti CD, Kumar P, Yamashiro KJ, Paxton ZJ, Reynaga L, Hyllen AA, Wang A, Farmer DL. PMID: 34217509; PMCID: PMC9365331.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    39. Neural crest-like stem cells for tissue regeneration. Stem Cells Transl Med. 2021 05; 10(5):681-693. Soto J, Ding X, Wang A, Li S. PMID: 33533168; PMCID: PMC8046096.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    40. Engineering mesenchymal stromal/stem cell-derived extracellular vesicles with improved targeting and therapeutic efficiency for the treatment of central nervous system disorders. Neural Regen Res. 2020 Dec; 15(12):2235-2236. Iavorovschi AM, Wang A. PMID: 32594034; PMCID: PMC7749490.
      View in: PubMed   Mentions: 6  
    41. A Dual Receptor Targeting- and BBB Penetrating- Peptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma. Int J Nanomedicine. 2020; 15:8875-8892. Lu L, Chen H, Wang L, Zhao L, Cheng Y, Wang A, Wang F, Zhang X. PMID: 33209022; PMCID: PMC7669533.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. Surviving Lambs with Myelomeningocele Repaired in utero with Placental Mesenchymal Stromal Cells for 6 Months: A Pilot Study. Fetal Diagn Ther. 2020; 47(12):912-917. Yamashiro K, Galganski LA, Peyton J, Haynes K, Vicuna V, Kumar P, Keller B, Becker J, Pivetti C, Stokes S, Theodorou C, Jackson J, Wang A, Farmer D. PMID: 33166951; PMCID: PMC7746588.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    43. Editorial: Nanotechnology in Cardiovascular Regenerative Medicine. Front Bioeng Biotechnol. 2020; 8:608844. Cui W, Wang A, Zhao C, Zhu W. PMID: 33195180; PMCID: PMC7644819.
      View in: PubMed   Mentions: 1  
    44. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591. Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. PMID: 32929084; PMCID: PMC7490264.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    45. Developing an Injectable Nanofibrous Extracellular Matrix Hydrogel With an Integrin αvβ3 Ligand to Improve Endothelial Cell Survival, Engraftment and Vascularization. Front Bioeng Biotechnol. 2020; 8:890. Hao D, Liu R, Gao K, He C, He S, Zhao C, Sun G, Farmer DL, Panitch A, Lam KS, Wang A. PMID: 32850742; PMCID: PMC7403189.
      View in: PubMed   Mentions: 6  
    46. Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease. Stem Cell Res Ther. 2020 07 22; 11(1):304. Amorim RM, Clark KC, Walker NJ, Kumar P, Herout K, Borjesson DL, Wang A. PMID: 32698861; PMCID: PMC7374910.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    47. Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity. Mol Cell. 2020 07 16; 79(2):304-319.e7. Zhang Z, Fang X, Wu X, Ling L, Chu F, Li J, Wang S, Zang J, Zhang B, Ye S, Zhang L, Yang B, Lin S, Huang H, Wang A, Zhou F. PMID: 32679077.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    48. Extracellular Matrix Mimicking Nanofibrous Scaffolds Modified With Mesenchymal Stem Cell-Derived Extracellular Vesicles for Improved Vascularization. Front Bioeng Biotechnol. 2020; 8:633. Hao D, Swindell HS, Ramasubramanian L, Liu R, Lam KS, Farmer DL, Wang A. PMID: 32671037; PMCID: PMC7329993.
      View in: PubMed   Mentions: 25  
    49. Identity and lineage fate of proteolipid protein 1 gene (Plp1)-expressing cells in the embryonic murine spinal cord. Dev Dyn. 2020 08; 249(8):946-960. Guo S, Wang Y, Wang A. PMID: 32353175.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    50. Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways. Nat Commun. 2020 04 24; 11(1):2027. Zhang S, Kim B, Zhu X, Gui X, Wang Y, Lan Z, Prabhu P, Fond K, Wang A, Guo F. PMID: 32332719; PMCID: PMC7181614.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    51. A Dual Role of Type I Interferons in Antitumor Immunity. Adv Biosyst. 2020 11; 4(11):e1900237. Zhou L, Zhang Y, Wang Y, Zhang M, Sun W, Dai T, Wang A, Wu X, Zhang S, Wang S, Zhou F. PMID: 33245214.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    52. Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A. Stem Cells Transl Med. 2020 06; 9(6):686-696. Rose M, Gao K, Cortez-Toledo E, Agu E, Hyllen AA, Conroy K, Pan G, Nolta JA, Wang A, Zhou P. PMID: 32162786; PMCID: PMC7214661.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    53. Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomater. 2020 05; 108:178-193. Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. PMID: 32151698; PMCID: PMC8012081.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    54. The Influence of Electron Beam Sterilization on In Vivo Degradation of β-TCP/PCL of Different Composite Ratios for Bone Tissue Engineering. Micromachines (Basel). 2020 Mar 06; 11(3). Kang JH, Kaneda J, Jang JG, Sakthiabirami K, Lui E, Kim C, Wang A, Park SW, Yang YP. PMID: 32155781; PMCID: PMC7142760.
      View in: PubMed   Mentions: 8  
    55. Fibrin Glue/Fibronectin/Heparin-Based Delivery System of BMP2 Induces Osteogenesis in MC3T3-E1 Cells and Bone Formation in Rat Calvarial Critical-Sized Defects. ACS Appl Mater Interfaces. 2020 Mar 18; 12(11):13400-13410. Ao Q, Wang S, He Q, Ten H, Oyama K, Ito A, He J, Javed R, Wang A, Matsuno A. PMID: 32091872.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    56. Multi-scale cellular engineering: From molecules to organ-on-a-chip. APL Bioeng. 2020 Mar; 4(1):010906. Huang NF, Chaudhuri O, Cahan P, Wang A, Engler AJ, Wang Y, Kumar S, Khademhosseini A, Li S. PMID: 32161833; PMCID: PMC7054123.
      View in: PubMed   Mentions: 5  
    57. Clonal isolation of endothelial colony-forming cells from early gestation chorionic villi of human placenta for fetal tissue regeneration. World J Stem Cells. 2020 Feb 26; 12(2):123-138. Gao K, He S, Kumar P, Farmer D, Zhou J, Wang A. PMID: 32184937; PMCID: PMC7062038.
      View in: PubMed   Mentions: 7  
    58. Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved the adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new insight for fetal tissue engineering. J Mater Chem B. 2020 02 26; 8(8):1649-1659. Hao D, Ma B, He C, Liu R, Farmer DL, Lam KS, Wang A. PMID: 32011618; PMCID: PMC7353926.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    59. A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss. Fetal Diagn Ther. 2020; 47(6):507-513. Galganski LA, Yamashiro KJ, Pivetti CD, Keller BA, Becker JC, Brown EG, Saadai P, Hirose S, Wang A, Farmer DL. PMID: 32097922; PMCID: PMC7305949.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    60. Engineering Extracellular Vesicles as Nanotherapeutics for Regenerative Medicine. Biomolecules. 2019 12 28; 10(1). Ramasubramanian L, Kumar P, Wang A. PMID: 31905611; PMCID: PMC7023093.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
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    132. In vitro regulation of neural differentiation and axon growth by growth factors and bioactive nanofibers. Tissue Eng Part A. 2010 Aug; 16(8):2641-8. Lam HJ, Patel S, Wang A, Chu J, Li S. PMID: 20367289; PMCID: PMC2947452.
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    133. The effect of topology of chitosan biomaterials on the differentiation and proliferation of neural stem cells. Acta Biomater. 2010 Sep; 6(9):3630-9. Wang G, Ao Q, Gong K, Wang A, Zheng L, Gong Y, Zhang X. PMID: 20371303.
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    134. Transforming growth factor-beta and notch signaling mediate stem cell differentiation into smooth muscle cells. Stem Cells. 2010 Apr; 28(4):734-42. Kurpinski K, Lam H, Chu J, Wang A, Kim A, Tsay E, Agrawal S, Schaffer DV, Li S. PMID: 20146266.
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    135. Nanofibrous Patches for Spinal Cord Regeneration. Adv Funct Mater. 2010 May 10; 20(9):1433-1440. Zhu Y, Wang A, Shen W, Patel S, Zhang R, Young W, Li S. PMID: 23378825; PMCID: PMC3558949.
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    136. An improved method for isolating Schwann cells from postnatal rat sciatic nerves. Cell Tissue Res. 2009 Sep; 337(3):361-9. Wei Y, Zhou J, Zheng Z, Wang A, Ao Q, Gong Y, Zhang X. PMID: 19639342.
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    137. The behavior of MC3T3-E1 cells on chitosan/poly-L-lysine composite films: effect of nanotopography, surface chemistry, and wettability. J Biomed Mater Res A. 2009 May; 89(2):453-65. Zheng Z, Zhang L, Kong L, Wang A, Gong Y, Zhang X. PMID: 18431777.
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    138. The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation. J Biol Chem. 2008 May 23; 283(21):14506-15. Zhou F, Zhang L, Wang A, Song B, Gong K, Zhang L, Hu M, Zhang X, Zhao N, Gong Y. PMID: 18367454.
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    139. LEF-1 activates the transcription of E2F1. Biochem Biophys Res Commun. 2008 Jan 04; 365(1):149-53. Zhou F, Zhang L, Gong K, Lu G, Sheng B, Wang A, Zhao N, Zhang X, Gong Y. PMID: 17980157.
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    140. In vitro cytotoxicity and protein drug release properties of chitosan/heparin microspheres. Tsinghua Science & Technology. 2007 Aug 1; 12(4):361-365. He HQ, Ao AQ, Wang WA, Gong GY, Zhao ZN, Zhang ZX. .
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    141. Physical properties and biocompatibility of a porous chitosan-based fiber-reinforced conduit for nerve regeneration. Biotechnol Lett. 2007 Nov; 29(11):1697-702. Wang A, Ao Q, Wei Y, Gong K, Liu X, Zhao N, Gong Y, Zhang X. PMID: 17628751.
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    142. Combined transplantation of neural stem cells and olfactory ensheathing cells for the repair of spinal cord injuries. Med Hypotheses. 2007; 69(6):1234-7. Ao Q, Wang AJ, Chen GQ, Wang SJ, Zuo HC, Zhang XF. PMID: 17548168.
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    143. Preparation and characterization of a multilayer biomimetic scaffold for bone tissue engineering. J Biomater Appl. 2007 Nov; 22(3):223-39. Kong L, Ao Q, Wang A, Gong K, Wang X, Lu G, Gong Y, Zhao N, Zhang X. PMID: 17255157.
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    144. Porous chitosan tubular scaffolds with knitted outer wall and controllable inner structure for nerve tissue engineering. J Biomed Mater Res A. 2006 Oct; 79(1):36-46. Wang A, Ao Q, Cao W, Yu M, He Q, Kong L, Zhang L, Gong Y, Zhang X. PMID: 16758450.
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    145. Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment. Biomacromolecules. 2006 Aug; 7(8):2327-30. Qi H, Hu P, Xu J, Wang A. PMID: 16903678.
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    146. A sandwich tubular scaffold derived from chitosan for blood vessel tissue engineering. J Biomed Mater Res A. 2006 May; 77(2):277-84. Zhang L, Ao Q, Wang A, Lu G, Kong L, Gong Y, Zhao N, Zhang X. PMID: 16400655.
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    147. Manufacture of multimicrotubule chitosan nerve conduits with novel molds and characterization in vitro. J Biomed Mater Res A. 2006 Apr; 77(1):11-8. Ao Q, Wang A, Cao W, Zhang L, Kong L, He Q, Gong Y, Zhang X. PMID: 16345091.
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    148. Protective effects of extract of Ginkgo biloba (EGb 761) on nerve cells after spinal cord injury in rats. Spinal Cord. 2006 Nov; 44(11):662-7. Ao Q, Sun XH, Wang AJ, Fu PF, Gong K, Zuo HC, Zuo HZ, Gong YD, Zhang XF. PMID: 16415923.
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    149. Fiber-Based chitosan tubular scaffolds for soft tissue engineering: Fabrication and in vitro evaluation. Tsinghua Science & Technology. 2005 Aug 1; 10(4):449-453. Wang WA, Ao AQ, Cao CW, Zhao ZC, Gong GY, Zhao ZN, Zhang ZX. .
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    150. Fabrication and characterization of chitosan nerve conduits with microtubular architectures. Tsinghua Science & Technology. 2005 Aug 1; 10(4):435-438. Ao AQ, Wang WA, Cao CW, Zhao ZC, Gong GY, Zhao ZN, Zhang ZX. .
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    151. Novel biodegradable films and scaffolds of chitosan blended with poly(3-hydroxybutyrate). J Biomater Sci Polym Ed. 2005; 16(11):1379-94. Cao W, Wang A, Jing D, Gong Y, Zhao N, Zhang X. PMID: 16370239.
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