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Steven C George

Title(s)Professor, Biomedical Engineering
SchoolUniversity of California, Davis
Phone530-752-9978
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    A 3D IN VITRO DISEASE MODEL OF ATRIAL CONDUCTION
    NIH/NHLBI UH3HL141800Sep 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    A 3D IN VITRO DISEASE MODEL OF ATRIAL CONDUCTION
    NIH/NHLBI UG3HL141800Sep 1, 2017 - Jul 31, 2019
    Role: Principal Investigator
    (PQ8) BONE MARROW-ON-A-CHIP:AN INVITRO 3D MODEL OF BREAST CANCER DORMANCY
    NIH/NCI R21CA208519Sep 1, 2016 - Aug 31, 2018
    Role: Principal Investigator
    A 3-D biomimetic human islet to model beta cell function in health and disease
    NIH/NIDDK UC4DK104202Sep 20, 2014 - Jun 30, 2019
    Role: Co-Principal Investigator
    Training Program in Cardiovascular Applied Research and Entrepreneurship
    NIH/NHLBI T32HL116270Jun 1, 2013 - May 31, 2023
    Role: Co-Principal Investigator
    A 3-D In Vitro Platform of Tumor Metastasis (PQ24)
    NIH/NCI R01CA170879Aug 20, 2012 - Jun 30, 2016
    Role: Principal Investigator
    An integrated in vitro model of perfused tumor and cardiac tissue
    NIH/NCATS UH3TR000481Jul 24, 2012 - Jun 30, 2017
    Role: Principal Investigator
    An integrated in vitro model of perfused tumor and cardiac tissue
    NIH/NCATS UH2TR000481Jul 24, 2012 - Jun 30, 2014
    Role: Principal Investigator
    Creating a prevascularized thick implantable human tissue
    NIH/NHLBI R21HL104203Jun 1, 2010 - Apr 30, 2013
    Role: Principal Investigator
    3-D microtissues with perfused human capillaries
    NIH/NIEHS RC1ES018361Sep 24, 2009 - Jun 30, 2011
    Role: Principal Investigator
    Exhaled Nitric Oxide: Mechanisms and Limitations
    NIH/NHLBI R01HL070645Apr 1, 2002 - Jun 30, 2011
    Role: Principal Investigator
    Linking Biological, Optical, and Mechanical Properties in the Airway Mucosa
    NIH/NHLBI R01HL067954Aug 1, 2001 - Jul 31, 2014
    Role: Principal Investigator
    CHARACTERIZING NITRIC OXIDE EXCHANGE IN THE LUNGS
    NIH/NHLBI R29HL060636Aug 1, 1998 - Jul 31, 2003
    Role: Principal Investigator
    AIRWAY GAS EXCHANGE AND THE BRONCHIAL CIRCULATION
    NIH/NHLBI F32HL009117Dec 30, 1994
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Weng KC, Kurokawa YK, Hajek BS, Paladin JA, Shirure VS, George SC. Human iPS-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anti-Cancer Efficacy and Cardiotoxicity. Tissue Eng Part C Methods. 2019 Dec 04. PMID: 31797733.
      View in: PubMed
    2. Hwang PY, Brenot A, King AC, Longmore GD, George SC. Randomly Distributed K14+ Breast Tumor Cells Polarize to the Leading Edge and Guide Collective Migration in Response to Chemical and Mechanical Environmental Cues. Cancer Res. 2019 Apr 15; 79(8):1899-1912. PMID: 30862718.
      View in: PubMed
    3. Lam SF, Shirure VS, Chu YE, Soetikno AG, George SC. Microfluidic device to attain high spatial and temporal control of oxygen. PLoS One. 2018; 13(12):e0209574. PMID: 30571786.
      View in: PubMed
    4. Natividad-Diaz SL, Browne S, Jha AK, Ma Z, Hossainy S, Kurokawa YK, George SC, Healy KE. A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis. Biomaterials. 2019 02; 194:73-83. PMID: 30583150.
      View in: PubMed
    5. Gaetani R, Aouad S, Demaddalena LL, Straessle H, Dzieciatkowska M, Wortham M, Bender HR, Nguyen-Ngoc KV, Schmid-Schoenbein GW, George SC, Hughes CCW, Sander M, Hansen KC, Christman KL. Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels. Tissue Eng Part C Methods. 2018 Nov 06. PMID: 30398401.
      View in: PubMed
    6. Shirure VS, Bi Y, Curtis MB, Lezia A, Goedegebuure MM, Goedegebuure SP, Aft R, Fields RC, George SC. Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids. Lab Chip. 2018 12 07; 18(23):3687-3702. PMID: 30393802.
      View in: PubMed
    7. Kurokawa YK, Shang MR, Yin RT, George SC. Modeling trastuzumab-related cardiotoxicity in vitro using human stem cell-derived cardiomyocytes. Toxicol Lett. 2018 Mar 15; 285:74-80. PMID: 29305325.
      View in: PubMed
    8. Sewell-Loftin MK, Bayer SVH, Crist E, Hughes T, Joison SM, Longmore GD, George SC. Cancer-associated fibroblasts support vascular growth through mechanical force. Sci Rep. 2017 10 03; 7(1):12574. PMID: 28974764.
      View in: PubMed
    9. Traore MA, George SC. Tissue Engineering the Vascular Tree. Tissue Eng Part B Rev. 2017 12; 23(6):505-514. PMID: 28799844.
      View in: PubMed
    10. Kurokawa YK, Yin RT, Shang MR, Shirure VS, Moya ML, George SC. Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Three-Dimensional Microphysiological Systems. Tissue Eng Part C Methods. 2017 08; 23(8):474-484. PMID: 28622076.
      View in: PubMed
    11. Schaberg KE, Shirure VS, Worley EA, George SC, Naegle KM. Ensemble clustering of phosphoproteomic data identifies differences in protein interactions and cell-cell junction integrity of HER2-overexpressing cells. Integr Biol (Camb). 2017 06 19; 9(6):539-547. PMID: 28492659.
      View in: PubMed
    12. Shirure VS, Lezia A, Tao A, Alonzo LF, George SC. Low levels of physiological interstitial flow eliminate morphogen gradients and guide angiogenesis. Angiogenesis. 2017 Nov; 20(4):493-504. PMID: 28608153.
      View in: PubMed
    13. Shirure VS, George SC. Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Lab Chip. 2017 02 14; 17(4):681-690. PMID: 28102869.
      View in: PubMed
    14. Phan DT, Bender RHF, Andrejecsk JW, Sobrino A, Hachey SJ, George SC, Hughes CC. Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface. Exp Biol Med (Maywood). 2017 11; 242(17):1669-1678. PMID: 28195514.
      View in: PubMed
    15. Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW. A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications. Lab Chip. 2017 01 31; 17(3):511-520. PMID: 28092382.
      View in: PubMed
    16. George SC, Meyerand ME. Challenges and Opportunities: Building a Relationship Between a Department of Biomedical Engineering and a Medical School. Ann Biomed Eng. 2017 03; 45(3):521-524. PMID: 28070773.
      View in: PubMed
    17. Wang X, Phan DTT, George SC, Hughes CCW, Lee AP. 3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels. Methods Mol Biol. 2017; 1612:325-344. PMID: 28634954.
      View in: PubMed
    18. Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC. 3D microtumors in vitro supported by perfused vascular networks. Sci Rep. 2016 08 23; 6:31589. PMID: 27549930.
      View in: PubMed
    19. Fong AH, Romero-López M, Heylman CM, Keating M, Tran D, Sobrino A, Tran AQ, Pham HH, Fimbres C, Gershon PD, Botvinick EL, George SC, Hughes CC. Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Tissue Eng Part A. 2016 08; 22(15-16):1016-25. PMID: 27392582.
      View in: PubMed
    20. Datta R, Heylman C, George SC, Gratton E. Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. Biomed Opt Express. 2016 May 01; 7(5):1690-701. PMID: 27231614.
      View in: PubMed
    21. Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP. An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms. Lab Chip. 2016 Mar 07; 16(5):868-876. PMID: 26879519.
      View in: PubMed
    22. Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP. Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels. Lab Chip. 2016 Jan 21; 16(2):282-90. PMID: 26616908.
      View in: PubMed
    23. Heylman C, Datta R, Sobrino A, George S, Gratton E. Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. PLoS One. 2015; 10(12):e0144572. PMID: 26695765.
      View in: PubMed
    24. Kurokawa YK, George SC. Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. Adv Drug Deliv Rev. 2016 Jan 15; 96:225-33. PMID: 26212156.
      View in: PubMed
    25. Alonzo LF, Moya ML, Shirure VS, George SC. Microfluidic device to control interstitial flow-mediated homotypic and heterotypic cellular communication. Lab Chip. 2015 Sep 07; 15(17):3521-9. PMID: 26190172.
      View in: PubMed
    26. Lee EK, Kurokawa YK, Tu R, George SC, Khine M. Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. Sci Rep. 2015 Jul 03; 5:11817. PMID: 26139150.
      View in: PubMed
    27. Merna N, Fung KM, Wang JJ, King CR, Hansen KC, Christman KL, George SC. Differential ß3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. Tissue Eng Part A. 2015 Aug; 21(15-16):2195-205. PMID: 25926101.
      View in: PubMed
    28. Ehsan SM, George SC. Vessel network formation in response to intermittent hypoxia is frequency dependent. J Biosci Bioeng. 2015 Sep; 120(3):347-50. PMID: 25735591.
      View in: PubMed
    29. White SM, Pittman CR, Hingorani R, Arora R, Esipova TV, Vinogradov SA, Hughes CC, Choi B, George SC. Implanted cell-dense prevascularized tissues develop functional vasculature that supports reoxygenation after thrombosis. Tissue Eng Part A. 2014 Sep; 20(17-18):2316-28. PMID: 24593148.
      View in: PubMed
    30. Ehsan SM, Welch-Reardon KM, Waterman ML, Hughes CC, George SC. A three-dimensional in vitro model of tumor cell intravasation. Integr Biol (Camb). 2014 Jun; 6(6):603-10. PMID: 24763498.
      View in: PubMed
    31. Heylman C, Sobrino A, Shirure VS, Hughes CC, George SC. A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening. Exp Biol Med (Maywood). 2014 Sep; 239(9):1240-54. PMID: 24740872.
      View in: PubMed
    32. Welch-Reardon KM, Ehsan SM, Wang K, Wu N, Newman AC, Romero-Lopez M, Fong AH, George SC, Edwards RA, Hughes CC. Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci. 2014 May 01; 127(Pt 9):2017-28. PMID: 24554431.
      View in: PubMed
    33. Moya ML, George SC. Integrating in vitro organ-specific function with the microcirculation. Curr Opin Chem Eng. 2014 Feb 01; 3:103-111. PMID: 24729953.
      View in: PubMed
    34. Moya ML, Alonzo LF, George SC. Microfluidic device to culture 3D in vitro human capillary networks. Methods Mol Biol. 2014; 1202:21-7. PMID: 24155229.
      View in: PubMed
    35. Moya M, Tran D, George SC. An integrated in vitro model of perfused tumor and cardiac tissue. Stem Cell Res Ther. 2013; 4 Suppl 1:S15. PMID: 24565445.
      View in: PubMed
    36. Robertson C, Heidari AE, Chen Z, George SC. Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis. J Biomech. 2014 Feb 07; 47(3):755-8. PMID: 24388166.
      View in: PubMed
    37. Hsu YH, Moya ML, Hughes CC, George SC, Lee AP. A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. Lab Chip. 2013 Aug 07; 13(15):2990-8. PMID: 23723013.
      View in: PubMed
    38. Gelb AF, Singh DH, Moridzadeh R, Fraser C, Tran D, Verbanck S, George SC. Age-stratified comparison of large and peripheral airway/alveolar nitric oxide levels in children and young adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1222-4. PMID: 23932460.
      View in: PubMed
    39. Robertson C, Ikemura K, Krasieva TB, George SC. Multiscale analysis of collagen microstructure with generalized image correlation spectroscopy and the detection of tissue prestress. Biomaterials. 2013 Aug; 34(26):6127-32. PMID: 23642533.
      View in: PubMed
    40. Robertson C, Tran DD, George SC. Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. Stem Cells. 2013 May; 31(5):829-37. PMID: 23355363.
      View in: PubMed
    41. Merna N, Robertson C, La A, George SC. Optical imaging predicts mechanical properties during decellularization of cardiac tissue. Tissue Eng Part C Methods. 2013 Oct; 19(10):802-9. PMID: 23469868.
      View in: PubMed
    42. Ehsan SM, George SC. Nonsteady state oxygen transport in engineered tissue: implications for design. Tissue Eng Part A. 2013 Jun; 19(11-12):1433-42. PMID: 23350630.
      View in: PubMed
    43. Moya ML, Hsu YH, Lee AP, Hughes CC, George SC. In vitro perfused human capillary networks. Tissue Eng Part C Methods. 2013 Sep; 19(9):730-7. PMID: 23320912.
      View in: PubMed
    44. He B, Baird R, Butera R, Datta A, George S, Hecht B, Hero A, Lazzi G, Lee RC, Liang J, Neuman M, Peng GC, Perreault EJ, Ramasubramanian M, Wang MD, Wikswo J, Yang GZ, Zhang YT. Grand challenges in interfacing engineering with life sciences and medicine. IEEE Trans Biomed Eng. 2013 Mar; 60(3):589-98. PMID: 23380847.
      View in: PubMed
    45. Zhou J, Alvarez-Elizondo MB, Botvinick E, George SC. Adenosine A(1) and prostaglandin E receptor 3 receptors mediate global airway contraction after local epithelial injury. Am J Respir Cell Mol Biol. 2013 Mar; 48(3):299-305. PMID: 23221044.
      View in: PubMed
    46. Shi Y, Aledia AS, Galant SP, George SC. Peripheral airway impairment measured by oscillometry predicts loss of asthma control in children. J Allergy Clin Immunol. 2013 Mar; 131(3):718-23. PMID: 23146376.
      View in: PubMed
    47. Hsu YH, Moya ML, Abiri P, Hughes CC, George SC, Lee AP. Full range physiological mass transport control in 3D tissue cultures. Lab Chip. 2013 Jan 07; 13(1):81-9. PMID: 23090158.
      View in: PubMed
    48. Robertson C, George SC. Theory and practical recommendations for autocorrelation-based image correlation spectroscopy. J Biomed Opt. 2012 Aug; 17(8):080801-1. PMID: 23224160.
      View in: PubMed
    49. Shi Y, Tatavoosian AV, Aledia AS, George SC, Galant SP. Cut points for Asthma Control Tests in Mexican children in Orange County, California. Ann Allergy Asthma Immunol. 2012 Aug; 109(2):108-13. PMID: 22840251.
      View in: PubMed
    50. Gelb AF, Barnes PJ, George SC, Ricciardolo FL, DiMaria G, Zamel N. Review of exhaled nitric oxide in chronic obstructive pulmonary disease. J Breath Res. 2012 Dec; 6(4):047101. PMID: 22677633.
      View in: PubMed
    51. Kim JH, Peacock MR, George SC, Hughes CC. BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II. Angiogenesis. 2012 Sep; 15(3):497-509. PMID: 22622516.
      View in: PubMed
    52. White SM, Hingorani R, Arora RP, Hughes CC, George SC, Choi B. Longitudinal in vivo imaging to assess blood flow and oxygenation in implantable engineered tissues. Tissue Eng Part C Methods. 2012 Sep; 18(9):697-709. PMID: 22435776.
      View in: PubMed
    53. Gelb AF, Moridzadeh R, Singh DH, Fraser C, George SC. In moderate-to-severe asthma patients monitoring exhaled nitric oxide during exacerbation is not a good predictor of spirometric response to oral corticosteroid. J Allergy Clin Immunol. 2012 Jun; 129(6):1491-8. PMID: 22560478.
      View in: PubMed
    54. Verbanck S, Malinovschi A, George S, Gelb AF, Vincken W, Van Muylem A. Bronchial and alveolar components of exhaled nitric oxide and their relationship. Eur Respir J. 2012 May; 39(5):1258-61. PMID: 22547733.
      View in: PubMed
    55. Shi Y, Aledia AS, Tatavoosian AV, Vijayalakshmi S, Galant SP, George SC. Relating small airways to asthma control by using impulse oscillometry in children. J Allergy Clin Immunol. 2012 Mar; 129(3):671-8. PMID: 22178635.
      View in: PubMed
    56. Zhou J, Alvarez-Elizondo MB, Botvinick E, George SC. Local small airway epithelial injury induces global smooth muscle contraction and airway constriction. J Appl Physiol (1985). 2012 Feb; 112(4):627-37. PMID: 22114176.
      View in: PubMed
    57. Robertson C, Lee SW, Ahn YC, Mahon S, Chen Z, Brenner M, George SC. Investigating in vivo airway wall mechanics during tidal breathing with optical coherence tomography. J Biomed Opt. 2011 Oct; 16(10):106011. PMID: 22029358.
      View in: PubMed
    58. George SC, Hlastala MP. Airway gas exchange and exhaled biomarkers. Compr Physiol. 2011 Oct; 1(4):1837-59. PMID: 23733690.
      View in: PubMed
    59. Tian L, George SC. Biomaterials to prevascularize engineered tissues. J Cardiovasc Transl Res. 2011 Oct; 4(5):685-98. PMID: 21892744.
      View in: PubMed
    60. Jiang J, George SC. TGF-ß2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Sep; 301(3):L361-7. PMID: 21685242.
      View in: PubMed
    61. Jiang J, George SC. Modeling gas phase nitric oxide release in lung epithelial cells. Nitric Oxide. 2011 Oct 30; 25(3):275-81. PMID: 21550413.
      View in: PubMed
    62. White SM, George SC, Choi B. Automated computation of functional vascular density using laser speckle imaging in a rodent window chamber model. Microvasc Res. 2011 Jul; 82(1):92-5. PMID: 21419785.
      View in: PubMed
    63. Miller C, George S, Niklason L. Developing a tissue-engineered model of the human bronchiole. J Tissue Eng Regen Med. 2010 Dec; 4(8):619-27. PMID: 20603896.
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    64. Delfino RJ, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, George SC, Shafer MM, Schauer JJ, Sioutas C. Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort. Epidemiology. 2010 Nov; 21(6):892-902. PMID: 20811287.
      View in: PubMed
    65. Barnes PJ, Dweik RA, Gelb AF, Gibson PG, George SC, Grasemann H, Pavord ID, Ratjen F, Silkoff PE, Taylor DR, Zamel N. Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest. 2010 Sep; 138(3):682-92. PMID: 20822990.
      View in: PubMed
    66. Gelb AF, George SC, Camacho F, Fraser C, Flynn Taylor C, Shakkottai S. Increased nitric oxide concentrations in the small airway of older normal subjects. Chest. 2011 Feb; 139(2):368-375. PMID: 20705799.
      View in: PubMed
    67. Raub CB, Putnam AJ, Tromberg BJ, George SC. Predicting bulk mechanical properties of cellularized collagen gels using multiphoton microscopy. Acta Biomater. 2010 Dec; 6(12):4657-65. PMID: 20620246.
      View in: PubMed
    68. Gelb AF, George SC, Silkoff PE, Krishnan A, Fraser C, Taylor CF, Shinar CM, Maginot T. Central and peripheral airway/alveolar sites of exhaled nitric oxide in acute asthma. Thorax. 2010 Jul; 65(7):619-25. PMID: 20627920.
      View in: PubMed
    69. Puckett JL, Taylor RW, Leu SY, Guijon OL, Aledia AS, Galant SP, George SC. Clinical patterns in asthma based on proximal and distal airway nitric oxide categories. Respir Res. 2010 Apr 28; 11:47. PMID: 20426813.
      View in: PubMed
    70. Puckett JL, Taylor RW, Leu SY, Guijon OL, Aledia AS, Galant SP, George SC. An elevated bronchodilator response predicts large airway inflammation in mild asthma. Pediatr Pulmonol. 2010 Feb; 45(2):174-81. PMID: 20082343.
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    71. Puckett JL, Taylor RW, Galant SP, George SC. Impact of analysis interval on the multiple exhalation flow technique to partition exhaled nitric oxide. Pediatr Pulmonol. 2010 Feb; 45(2):182-91. PMID: 20082344.
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    72. Chen X, Aledia AS, Popson SA, Him L, Hughes CC, George SC. Rapid anastomosis of endothelial progenitor cell-derived vessels with host vasculature is promoted by a high density of cotransplanted fibroblasts. Tissue Eng Part A. 2010 Feb; 16(2):585-94. PMID: 19737050.
      View in: PubMed
    73. Shelley DA, Puckett JL, George SC. Quantifying proximal and distal sources of NO in asthma using a multicompartment model. J Appl Physiol (1985). 2010 Apr; 108(4):821-9. PMID: 20093668.
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    74. Ghajar CM, Kachgal S, Kniazeva E, Mori H, Costes SV, George SC, Putnam AJ. Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms. Exp Cell Res. 2010 Mar 10; 316(5):813-25. PMID: 20067788.
      View in: PubMed
    75. Raub CB, Mahon S, Narula N, Tromberg BJ, Brenner M, George SC. Linking optics and mechanics in an in vivo model of airway fibrosis and epithelial injury. J Biomed Opt. 2010 Jan-Feb; 15(1):015004. PMID: 20210444.
      View in: PubMed
    76. Griffith CK, George SC. The effect of hypoxia on in vitro prevascularization of a thick soft tissue. Tissue Eng Part A. 2009 Sep; 15(9):2423-34. PMID: 19292659.
      View in: PubMed
    77. Kreuter KA, Mahon SB, Mukai DS, Su J, Jung WG, Narula N, Guo S, Wakida N, Raub C, Berns MW, George SC, Chen Z, Brenner M. Detection and monitoring of early airway injury effects of half-mustard (2-chloroethylethylsulfide) exposure using high-resolution optical coherence tomography. J Biomed Opt. 2009 Jul-Aug; 14(4):044037. PMID: 19725748.
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    78. Chen X, Aledia AS, Ghajar CM, Griffith CK, Putnam AJ, Hughes CC, George SC. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Eng Part A. 2009 Jun; 15(6):1363-71. PMID: 18976155.
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    79. Arold SP, Malavia N, George SC. Mechanical compression attenuates normal human bronchial epithelial wound healing. Respir Res. 2009 Feb 12; 10:9. PMID: 19171062.
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    80. Jiang J, Malavia N, Suresh V, George SC. Nitric oxide gas phase release in human small airway epithelial cells. Respir Res. 2009 Jan 19; 10:3. PMID: 19152703.
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    81. Malavia NK, Raub CB, Mahon SB, Brenner M, Panettieri RA, George SC. Airway epithelium stimulates smooth muscle proliferation. Am J Respir Cell Mol Biol. 2009 Sep; 41(3):297-304. PMID: 19151317.
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    82. Puckett JL, George SC. Partitioned exhaled nitric oxide to non-invasively assess asthma. Respir Physiol Neurobiol. 2008 Nov 30; 163(1-3):166-77. PMID: 18718562.
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    83. Suresh V, Shelley DA, Shin HW, George SC. Effect of heterogeneous ventilation and nitric oxide production on exhaled nitric oxide profiles. J Appl Physiol (1985). 2008 Jun; 104(6):1743-52. PMID: 18356478.
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    84. Malavia NK, Mih JD, Raub CB, Dinh BT, George SC. IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respir Res. 2008 Mar 18; 9:27. PMID: 18348727.
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    85. George SC. How accurately should we estimate the anatomical source of exhaled nitric oxide? J Appl Physiol (1985). 2008 Apr; 104(4):909-11. PMID: 18258805.
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    86. Ghajar CM, George SC, Putnam AJ. Matrix metalloproteinase control of capillary morphogenesis. Crit Rev Eukaryot Gene Expr. 2008; 18(3):251-78. PMID: 18540825.
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    87. Raub CB, Unruh J, Suresh V, Krasieva T, Lindmo T, Gratton E, Tromberg BJ, George SC. Image correlation spectroscopy of multiphoton images correlates with collagen mechanical properties. Biophys J. 2008 Mar 15; 94(6):2361-73. PMID: 18065452.
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    88. Ghajar CM, Chen X, Harris JW, Suresh V, Hughes CC, Jeon NL, Putnam AJ, George SC. The effect of matrix density on the regulation of 3-D capillary morphogenesis. Biophys J. 2008 Mar 01; 94(5):1930-41. PMID: 17993494.
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    89. Tufvesson E, Aronsson D, Ankerst J, George SC, Bjermer L. Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness. Respir Med. 2007 Nov; 101(11):2321-6. PMID: 17686621.
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    90. Suresh V, Mih JD, George SC. Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2007 Jul; 37(1):97-104. PMID: 17347445.
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    91. Ghajar CM, Suresh V, Peyton SR, Raub CB, Meyskens FL, George SC, Putnam AJ. A novel three-dimensional model to quantify metastatic melanoma invasion. Mol Cancer Ther. 2007 Feb; 6(2):552-61. PMID: 17267658.
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    92. George SC. In Silico Modeling of Respiratory Structure, Function, and Disease. Drug Discov Today Dis Models. 2007; 4(3):123-124. PMID: 19568329.
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    93. Raub CB, Suresh V, Krasieva T, Lyubovitsky J, Mih JD, Putnam AJ, Tromberg BJ, George SC. Noninvasive assessment of collagen gel microstructure and mechanics using multiphoton microscopy. Biophys J. 2007 Mar 15; 92(6):2212-22. PMID: 17172303.
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    94. Shin HW, Shelley DA, Henderson EM, Fitzpatrick A, Gaston B, George SC. Airway nitric oxide release is reduced after PBS inhalation in asthma. J Appl Physiol (1985). 2007 Mar; 102(3):1028-33. PMID: 17110506.
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    95. Delfino RJ, Staimer N, Gillen D, Tjoa T, Sioutas C, Fung K, George SC, Kleinman MT. Personal and ambient air pollution is associated with increased exhaled nitric oxide in children with asthma. Environ Health Perspect. 2006 Nov; 114(11):1736-43. PMID: 17107861.
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    96. Ghajar CM, Blevins KS, Hughes CC, George SC, Putnam AJ. Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation. Tissue Eng. 2006 Oct; 12(10):2875-88. PMID: 17518656.
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    97. Thompson HG, Mih JD, Krasieva TB, Tromberg BJ, George SC. Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis. Am J Physiol Lung Cell Mol Physiol. 2006 Dec; 291(6):L1277-85. PMID: 16891397.
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    98. Condorelli P, Shin HW, Aledia AS, Silkoff PE, George SC. A simple technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model. J Appl Physiol (1985). 2007 Jan; 102(1):417-25. PMID: 16888048.
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    99. Shin HW, Schwindt CD, Aledia AS, Rose-Gottron CM, Larson JK, Newcomb RL, Cooper DM, George SC. Exercise-induced bronchoconstriction alters airway nitric oxide exchange in a pattern distinct from spirometry. Am J Physiol Regul Integr Comp Physiol. 2006 Dec; 291(6):R1741-8. PMID: 16840654.
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    100. Silkoff PE, Erzurum SC, Lundberg JO, George SC, Marczin N, Hunt JF, Effros R, Horvath I. ATS workshop proceedings: exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate. Proc Am Thorac Soc. 2006 Apr; 3(2):131-45. PMID: 16565422.
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    101. Thompson HG, Truong DT, Griffith CK, George SC. A three-dimensional in vitro model of angiogenesis in the airway mucosa. Pulm Pharmacol Ther. 2007; 20(2):141-8. PMID: 16414296.
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    102. Shin HW, Condorelli P, George SC. Examining axial diffusion of nitric oxide in the lungs using heliox and breath hold. J Appl Physiol (1985). 2006 Feb; 100(2):623-30. PMID: 16210445.
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    103. Rottier BL, Cohen J, van der Mark TW, Douma WR, Duiverman EJ, ten Hacken NH. A different analysis applied to a mathematical model on output of exhaled nitric oxide. J Appl Physiol (1985). 2005 Jul; 99(1):378-9; author reply 379-80. PMID: 16036910.
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    104. Griffith CK, Miller C, Sainson RC, Calvert JW, Jeon NL, Hughes CC, George SC. Diffusion limits of an in vitro thick prevascularized tissue. Tissue Eng. 2005 Jan-Feb; 11(1-2):257-66. PMID: 15738680.
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    105. Shin HW, Condorelli P, George SC. A new and more accurate technique to characterize airway nitric oxide using different breath-hold times. J Appl Physiol (1985). 2005 May; 98(5):1869-77. PMID: 15618319.
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    106. Shin HW, Condorelli P, Rose-Gottron CM, Cooper DM, George SC. Probing the impact of axial diffusion on nitric oxide exchange dynamics with heliox. J Appl Physiol (1985). 2004 Sep; 97(3):874-82. PMID: 15121738.
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    107. George SC, Hogman M, Permutt S, Silkoff PE. Modeling pulmonary nitric oxide exchange. J Appl Physiol (1985). 2004 Mar; 96(3):831-9. PMID: 14766761.
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    108. Jeh HS, Lu S, George SC. Encapsulation of PROLI/NO in biodegradable microparticles. J Microencapsul. 2004 Feb; 21(1):3-13. PMID: 14718181.
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    110. Shin HW, Rose-Gottron CM, Cooper DM, Newcomb RL, George SC. Airway diffusing capacity of nitric oxide and steroid therapy in asthma. J Appl Physiol (1985). 2004 Jan; 96(1):65-75. PMID: 12959957.
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    111. Shin HW, Rose-Gottron CM, Cooper DM, Hill M, George SC. Impact of high-intensity exercise on nitric oxide exchange in healthy adults. Med Sci Sports Exerc. 2003 Jun; 35(6):995-1003. PMID: 12783048.
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    112. Agarwal AR, Mih J, George SC. Expression of matrix proteins in an in vitro model of airway remodeling in asthma. Allergy Asthma Proc. 2003 Jan-Feb; 24(1):35-42. PMID: 12635576.
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    113. Shin HW, George SC. Impact of axial diffusion on nitric oxide exchange in the lungs. J Appl Physiol (1985). 2002 Dec; 93(6):2070-80. PMID: 12391103.
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    114. Condorelli P, George SC. Free nitric oxide diffusion in the bronchial microcirculation. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2660-70. PMID: 12388292.
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    115. Jeh HS, Georg SC. Dynamic modeling and simulation of nitric oxide gas delivery to pulmonary arterioles. Ann Biomed Eng. 2002 Jul-Aug; 30(7):946-60. PMID: 12398425.
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    116. Shin HW, Rose-Gottron CM, Sufi RS, Perez F, Cooper DM, Wilson AF, George SC. Flow-independent nitric oxide exchange parameters in cystic fibrosis. Am J Respir Crit Care Med. 2002 Feb 01; 165(3):349-57. PMID: 11818320.
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    117. Kwon S, Newcomb RL, George SC. Mechanisms of synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells. Nitric Oxide. 2001 Dec; 5(6):534-46. PMID: 11730360.
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    118. Shin HW, Rose-Gottron CM, Perez F, Cooper DM, Wilson AF, George SC. Flow-independent nitric oxide exchange parameters in healthy adults. J Appl Physiol (1985). 2001 Nov; 91(5):2173-81. PMID: 11641359.
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    119. Tsoukias NM, George SC. Impact of volume-dependent alveolar diffusing capacity on exhaled nitric oxide concentration. Ann Biomed Eng. 2001 Sep; 29(9):731-9. PMID: 11599581.
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    120. Tsoukias NM, Shin HW, Wilson AF, George SC. A single-breath technique with variable flow rate to characterize nitric oxide exchange dynamics in the lungs. J Appl Physiol (1985). 2001 Jul; 91(1):477-87. PMID: 11408466.
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    121. Condorelli P, George SC. In vivo control of soluble guanylate cyclase activation by nitric oxide: a kinetic analysis. Biophys J. 2001 May; 80(5):2110-9. PMID: 11325714.
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    122. Agarwal A, Coleno ML, Wallace VP, Wu WY, Sun CH, Tromberg BJ, George SC. Two-photon laser scanning microscopy of epithelial cell-modulated collagen density in engineered human lung tissue. Tissue Eng. 2001 Apr; 7(2):191-202. PMID: 11304454.
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    123. Shin HY, George SC. Microscopic modeling of NO and S-nitrosoglutathione kinetics and transport in human airways. J Appl Physiol (1985). 2001 Mar; 90(3):777-88. PMID: 11181583.
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    124. Högman M, Lúdvíksdóttir D, Anderson SD, George S, Håkansson L, Chan HK, Meriläinen P, Hedenström H. Inhaled mannitol shifts exhaled nitric oxide in opposite directions in asthmatics and healthy subjects. Respir Physiol. 2001 Jan; 124(2):141-50. PMID: 11164205.
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    125. Tsoukias NM, Dabdub D, Wilson AF, George SC. Effect of alveolar volume and sequential filling on the diffusing capacity of the lungs: II. Experiment. Respir Physiol. 2000 May; 120(3):251-71. PMID: 10828341.
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    126. Tsoukias NM, Wilson AF, George SC. Effect of alveolar volume and sequential filling on the diffusing capacity of the lungs: I. theory. Respir Physiol. 2000 May; 120(3):231-49. PMID: 10828340.
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    127. Kwon S, George SC. Synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells. Nitric Oxide. 1999 Aug; 3(4):348-57. PMID: 10444374.
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    128. Condorelli P, George SC. Theoretical gas phase mass transfer coefficients for endogenous gases in the lungs. Ann Biomed Eng. 1999 May-Jun; 27(3):326-39. PMID: 10374725.
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    129. Tsoukias NM, Tannous Z, Wilson AF, George SC. Single-exhalation profiles of NO and CO2 in humans: effect of dynamically changing flow rate. J Appl Physiol (1985). 1998 Aug; 85(2):642-52. PMID: 9688743.
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    130. Tsoukias NM, George SC. A two-compartment model of pulmonary nitric oxide exchange dynamics. J Appl Physiol (1985). 1998 Aug; 85(2):653-66. PMID: 9688744.
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    131. Bui TD, Dabdub D, George SC. Modeling bronchial circulation with application to soluble gas exchange: description and sensitivity analysis. J Appl Physiol (1985). 1998 Jun; 84(6):2070-88. PMID: 9609803.
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    132. George SC, Babb AL, Deffebach ME, Hlastala MP. Diffusion of nonelectrolytes in the canine trachea: effect of tight junction. J Appl Physiol (1985). 1996 May; 80(5):1687-95. PMID: 8727556.
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    133. George SC, Hlastala MP, Souders JE, Babb AL. Gas exchange in the airways. J Aerosol Med. 1996; 9(1):25-33. PMID: 10172721.
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    134. Souders JE, George SC, Polissar NL, Swenson ER, Hlastala MP. Tracheal gas exchange: perfusion-related differences in inert gas elimination. J Appl Physiol (1985). 1995 Sep; 79(3):918-28. PMID: 8567536.
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    135. George SC, Souders JE, Babb AL, Hlastala MP. Modeling steady-state inert gas exchange in the canine trachea. J Appl Physiol (1985). 1995 Sep; 79(3):929-40. PMID: 8567537.
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    136. George SC, Babb AL, Hlastala MP. Modeling the concentration of ethanol in the exhaled breath following pretest breathing maneuvers. Ann Biomed Eng. 1995 Jan-Feb; 23(1):48-60. PMID: 7762882.
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    137. George SC, Babb AL, Hlastala MP. Dynamics of soluble gas exchange in the airways. III. Single-exhalation breathing maneuver. J Appl Physiol (1985). 1993 Dec; 75(6):2439-49. PMID: 8125862.
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