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Eduardo A Silva

Title(s)Associate Professor, Biomedical Engineering
SchoolUniversity of California, Davis
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yamaguchi FSM, Shams S, Silva EA, Stilhano RS. PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. Int J Mol Sci. 2019 Oct 25; 20(21). PMID: 31717698.
      View in: PubMed
    2. Hadley DJ, Silva EA. Thaw-Induced Gelation of Alginate Hydrogels for Versatile Delivery of Therapeutics. Ann Biomed Eng. 2019 Aug; 47(8):1701-1710. PMID: 31044339.
      View in: PubMed
    3. Madrigal JL, Shams S, Stilhano RS, Silva EA. Characterizing the encapsulation and release of lentivectors and adeno-associated vectors from degradable alginate hydrogels. Biomater Sci. 2019 Jan 29; 7(2):645-656. PMID: 30534722.
      View in: PubMed
    4. Campbell KT, Stilhano RS, Silva EA. Enzymatically degradable alginate hydrogel systems to deliver endothelial progenitor cells for potential revasculature applications. Biomaterials. 2018 10; 179:109-121. PMID: 29980073.
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    5. Madrigal JL, Sharma SN, Campbell KT, Stilhano RS, Gijsbers R, Silva EA. Microgels produced using microfluidic on-chip polymer blending for controlled released of VEGF encoding lentivectors. Acta Biomater. 2018 03 15; 69:265-276. PMID: 29398644.
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    6. Torres AL, Bidarra SJ, Pinto MT, Aguiar PC, Silva EA, Barrias CC. Guiding morphogenesis in cell-instructive microgels for therapeutic angiogenesis. Biomaterials. 2018 Feb; 154:34-47. PMID: 29120817.
      View in: PubMed
    7. Williams PA, Campbell KT, Silva EA. Alginate hydrogels of varied molecular weight distribution enable sustained release of sphingosine-1-phosphate and promote angiogenesis. J Biomed Mater Res A. 2018 Jan; 106(1):138-146. PMID: 28875559.
      View in: PubMed
    8. Anderson EM, Silva EA, Hao Y, Martinick KD, Vermillion SA, Stafford AG, Doherty EG, Wang L, Doherty EJ, Grossman PM, Mooney DJ. VEGF and IGF Delivered from Alginate Hydrogels Promote Stable Perfusion Recovery in Ischemic Hind Limbs of Aged Mice and Young Rabbits. J Vasc Res. 2017; 54(5):288-298. PMID: 28930755.
      View in: PubMed
    9. Campbell KT, Hadley DJ, Kukis DL, Silva EA. Alginate hydrogels allow for bioactive and sustained release of VEGF-C and VEGF-D for lymphangiogenic therapeutic applications. PLoS One. 2017; 12(7):e0181484. PMID: 28723974.
      View in: PubMed
    10. Madrigal JL, Stilhano R, Silva EA. Biomaterial-Guided Gene Delivery for Musculoskeletal Tissue Repair. Tissue Eng Part B Rev. 2017 08; 23(4):347-361. PMID: 28166711.
      View in: PubMed
    11. Orbay H, Devi K, Williams PA, Dehghani T, Silva EA, Sahar DE. Comparison of Endothelial Differentiation Capacities of Human and Rat Adipose-Derived Stem Cells. Plast Reconstr Surg. 2016 Dec; 138(6):1231-1241. PMID: 27879591.
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    12. Williams PA, Campbell KT, Gharaviram H, Madrigal JL, Silva EA. Alginate-Chitosan Hydrogels Provide a Sustained Gradient of Sphingosine-1-Phosphate for Therapeutic Angiogenesis. Ann Biomed Eng. 2017 04; 45(4):1003-1014. PMID: 27904998.
      View in: PubMed
    13. Stilhano RS, Madrigal JL, Wong K, Williams PA, Martin PK, Yamaguchi FS, Samoto VY, Han SW, Silva EA. Injectable alginate hydrogel for enhanced spatiotemporal control of lentivector delivery in murine skeletal muscle. J Control Release. 2016 09 10; 237:42-9. PMID: 27374631.
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    14. Murphy KC, Stilhano RS, Mitra D, Zhou D, Batarni S, Silva EA, Leach JK. Hydrogel biophysical properties instruct coculture-mediated osteogenic potential. FASEB J. 2016 Jan; 30(1):477-86. PMID: 26443826.
      View in: PubMed
    15. Williams PA, Silva EA. The Role of Synthetic Extracellular Matrices in Endothelial Progenitor Cell Homing for Treatment of Vascular Disease. Ann Biomed Eng. 2015 Oct; 43(10):2301-13. PMID: 26206680.
      View in: PubMed
    16. Binder BY, Williams PA, Silva EA, Leach JK. Lysophosphatidic Acid and Sphingosine-1-Phosphate: A Concise Review of Biological Function and Applications for Tissue Engineering. Tissue Eng Part B Rev. 2015 Dec; 21(6):531-42. PMID: 26035484.
      View in: PubMed
    17. Tellechea A, Silva EA, Min J, Leal EC, Auster ME, Pradhan-Nabzdyk L, Shih W, Mooney DJ, Veves A. Alginate and DNA Gels Are Suitable Delivery Systems for Diabetic Wound Healing. Int J Low Extrem Wounds. 2015 Jun; 14(2):146-53. PMID: 26032947.
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    18. Williams PA, Stilhano RS, To VP, Tran L, Wong K, Silva EA. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). PLoS One. 2015; 10(4):e0123437. PMID: 25875493.
      View in: PubMed
    19. Brudno Y, Silva EA, Kearney CJ, Lewin SA, Miller A, Martinick KD, Aizenberg M, Mooney DJ. Refilling drug delivery depots through the blood. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):12722-7. PMID: 25139997.
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    20. Silva EA, Eseonu C, Mooney DJ. Endothelial cells expressing low levels of CD143 (ACE) exhibit enhanced sprouting and potency in relieving tissue ischemia. Angiogenesis. 2014 Jul; 17(3):617-30. PMID: 24414940.
      View in: PubMed
    21. Shamis Y, Silva EA, Hewitt KJ, Brudno Y, Levenberg S, Mooney DJ, Garlick JA. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS One. 2013; 8(12):e83755. PMID: 24386271.
      View in: PubMed
    22. Fonseca KB, Gomes DB, Lee K, Santos SG, Sousa A, Silva EA, Mooney DJ, Granja PL, Barrias CC. Injectable MMP-sensitive alginate hydrogels as hMSC delivery systems. Biomacromolecules. 2014 Jan 13; 15(1):380-90. PMID: 24345197.
      View in: PubMed
    23. Lui KO, Zangi L, Silva EA, Bu L, Sahara M, Li RA, Mooney DJ, Chien KR. Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA. Cell Res. 2013 Oct; 23(10):1172-86. PMID: 24018375.
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    24. Kodiyan A, Silva EA, Kim J, Aizenberg M, Mooney DJ. Surface modification with alginate-derived polymers for stable, protein-repellent, long-circulating gold nanoparticles. ACS Nano. 2012 Jun 26; 6(6):4796-805. PMID: 22650310.
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    25. Kaigler D, Silva EA, Mooney DJ. Guided bone regeneration using injectable vascular endothelial growth factor delivery gel. J Periodontol. 2013 Feb; 84(2):230-8. PMID: 22668339.
      View in: PubMed
    26. Vacharathit V, Silva EA, Mooney DJ. Viability and functionality of cells delivered from peptide conjugated scaffolds. Biomaterials. 2011 May; 32(15):3721-8. PMID: 21334064.
      View in: PubMed
    27. Kim J, Cao L, Shvartsman D, Silva EA, Mooney DJ. Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. Nano Lett. 2011 Feb 09; 11(2):694-700. PMID: 21192718.
      View in: PubMed
    28. Yuen WW, Du NR, Chan CH, Silva EA, Mooney DJ. Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17933-8. PMID: 20921366.
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    29. Lee K, Silva EA, Mooney DJ. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface. 2011 Feb 06; 8(55):153-70. PMID: 20719768.
      View in: PubMed
    30. Emerich DF, Silva E, Ali O, Mooney D, Bell W, Yu SJ, Kaneko Y, Borlongan C. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplant. 2010; 19(9):1063-71. PMID: 20412616.
      View in: PubMed
    31. Sun Q, Silva EA, Wang A, Fritton JC, Mooney DJ, Schaffler MB, Grossman PM, Rajagopalan S. Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis. Pharm Res. 2010 Feb; 27(2):264-71. PMID: 19953308.
      View in: PubMed
    32. Silva EA, Mooney DJ. Effects of VEGF temporal and spatial presentation on angiogenesis. Biomaterials. 2010 Feb; 31(6):1235-41. PMID: 19906422.
      View in: PubMed
    33. Silva EA, Kim ES, Kong HJ, Mooney DJ. Material-based deployment enhances efficacy of endothelial progenitor cells. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14347-52. PMID: 18794520.
      View in: PubMed
    34. Chen RR, Silva EA, Yuen WW, Brock AA, Fischbach C, Lin AS, Guldberg RE, Mooney DJ. Integrated approach to designing growth factor delivery systems. FASEB J. 2007 Dec; 21(14):3896-903. PMID: 17644610.
      View in: PubMed
    35. Mooney DJ, Silva EA. Tissue engineering: a glue for biomaterials. Nat Mater. 2007 May; 6(5):327-8. PMID: 17471269.
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    36. Hao X, Silva EA, Månsson-Broberg A, Grinnemo KH, Siddiqui AJ, Dellgren G, Wärdell E, Brodin LA, Mooney DJ, Sylvén C. Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction. Cardiovasc Res. 2007 Jul 01; 75(1):178-85. PMID: 17481597.
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    37. Pedruzzi I, Malvessi E, Mata VG, Silva EA, Silveira MM, Rodrigues AE. Quantification of lactobionic acid and sorbitol from enzymatic reaction of fructose and lactose by high-performance liquid chromatography. J Chromatogr A. 2007 Mar 23; 1145(1-2):128-32. PMID: 17306812.
      View in: PubMed
    38. Silva EA, Mooney DJ. Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis. J Thromb Haemost. 2007 Mar; 5(3):590-8. PMID: 17229044.
      View in: PubMed
    39. Chen RR, Silva EA, Yuen WW, Mooney DJ. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res. 2007 Feb; 24(2):258-64. PMID: 17191092.
      View in: PubMed
    40. Silva EA, Mooney DJ. Synthetic extracellular matrices for tissue engineering and regeneration. Curr Top Dev Biol. 2004; 64:181-205. PMID: 15563948.
      View in: PubMed