Eduardo A Silva

Title(s)Associate Professor, Biomedical Engineering
SchoolUniversity of California, Davis
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    1. Isolating and characterizing lymphatic endothelial progenitor cells for potential therapeutic lymphangiogenic applications. Acta Biomater. 2021 Aug 10. Campbell KT, Curtis MB, Massey JM, Wysoczynski K, Hadley DJ, George SC, Silva EA. PMID: 34384911.
      View in: PubMed   Mentions:    Fields:    
    2. Alginate-Based Bioinks for 3D Bioprinting and Fabrication of Anatomically Accurate Bone Grafts. Tissue Eng Part A. 2021 Sep; 27(17-18):1168-1181. Gonzalez-Fernandez T, Tenorio AJ, Campbell KT, Silva EA, Leach JK. PMID: 33218292.
      View in: PubMed   Mentions:    Fields:    
    3. Biomaterial Based Strategies for Engineering New Lymphatic Vasculature. Adv Healthc Mater. 2020 09; 9(18):e2000895. Campbell KT, Silva EA. PMID: 32734721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Biological responses to physicochemical properties of biomaterial surface. Chem Soc Rev. 2020 Aug 07; 49(15):5178-5224. Rahmati M, Silva EA, Reseland JE, A Heyward C, Haugen HJ. PMID: 32642749.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    5. Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nat Commun. 2020 04 30; 11(1):2102. Seo JW, Ingham ES, Mahakian L, Tumbale S, Wu B, Aghevlian S, Shams S, Baikoghli M, Jain P, Ding X, Goeden N, Dobreva T, Flytzanis NC, Chavez M, Singhal K, Leib R, James ML, Segal DJ, Cheng RH, Silva EA, Gradinaru V, Ferrara KW. PMID: 32355221.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    6. Tuning cytokines enriches dendritic cells and regulatory T cells in the periodontium. J Periodontol. 2020 11; 91(11):1475-1485. Sands RW, Verbeke CS, Ouhara K, Silva EA, Hsiong S, Kawai T, Mooney D. PMID: 32150760.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Computational-Based Design of Hydrogels with Predictable Mesh Properties. ACS Biomater Sci Eng. 2020 01 13; 6(1):308-319. Campbell KT, Wysoczynski K, Hadley DJ, Silva EA. PMID: 33313390.
      View in: PubMed   Mentions:
    8. PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. Int J Mol Sci. 2019 Oct 25; 20(21). Yamaguchi FSM, Shams S, Silva EA, Stilhano RS. PMID: 31717698.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Microvascular engineering: Dynamic changes in microgel-entrapped vascular cells correlates with higher vasculogenic/angiogenic potential. Biomaterials. 2020 01; 228:119554. Torres AL, Bidarra SJ, Vasconcelos DP, Barbosa JN, Silva EA, Nascimento DS, Barrias CC. PMID: 31677395.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    10. Thaw-Induced Gelation of Alginate Hydrogels for Versatile Delivery of Therapeutics. Ann Biomed Eng. 2019 Aug; 47(8):1701-1710. Hadley DJ, Silva EA. PMID: 31044339.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    11. Characterizing the encapsulation and release of lentivectors and adeno-associated vectors from degradable alginate hydrogels. Biomater Sci. 2019 Jan 29; 7(2):645-656. Madrigal JL, Shams S, Stilhano RS, Silva EA. PMID: 30534722.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    12. Enzymatically degradable alginate hydrogel systems to deliver endothelial progenitor cells for potential revasculature applications. Biomaterials. 2018 10; 179:109-121. Campbell KT, Stilhano RS, Silva EA. PMID: 29980073.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    13. Microgels produced using microfluidic on-chip polymer blending for controlled released of VEGF encoding lentivectors. Acta Biomater. 2018 03 15; 69:265-276. Madrigal JL, Sharma SN, Campbell KT, Stilhano RS, Gijsbers R, Silva EA. PMID: 29398644.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    14. Guiding morphogenesis in cell-instructive microgels for therapeutic angiogenesis. Biomaterials. 2018 Feb; 154:34-47. Torres AL, Bidarra SJ, Pinto MT, Aguiar PC, Silva EA, Barrias CC. PMID: 29120817.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    15. Alginate hydrogels of varied molecular weight distribution enable sustained release of sphingosine-1-phosphate and promote angiogenesis. J Biomed Mater Res A. 2018 Jan; 106(1):138-146. Williams PA, Campbell KT, Silva EA. PMID: 28875559.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. VEGF and IGF Delivered from Alginate Hydrogels Promote Stable Perfusion Recovery in Ischemic Hind Limbs of Aged Mice and Young Rabbits. J Vasc Res. 2017; 54(5):288-298. Anderson EM, Silva EA, Hao Y, Martinick KD, Vermillion SA, Stafford AG, Doherty EG, Wang L, Doherty EJ, Grossman PM, Mooney DJ. PMID: 28930755.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    17. Alginate hydrogels allow for bioactive and sustained release of VEGF-C and VEGF-D for lymphangiogenic therapeutic applications. PLoS One. 2017; 12(7):e0181484. Campbell KT, Hadley DJ, Kukis DL, Silva EA. PMID: 28723974.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Biomaterial-Guided Gene Delivery for Musculoskeletal Tissue Repair. Tissue Eng Part B Rev. 2017 08; 23(4):347-361. Madrigal JL, Stilhano R, Silva EA. PMID: 28166711.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Comparison of Endothelial Differentiation Capacities of Human and Rat Adipose-Derived Stem Cells. Plast Reconstr Surg. 2016 Dec; 138(6):1231-1241. Orbay H, Devi K, Williams PA, Dehghani T, Silva EA, Sahar DE. PMID: 27879591.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    20. Alginate-Chitosan Hydrogels Provide a Sustained Gradient of Sphingosine-1-Phosphate for Therapeutic Angiogenesis. Ann Biomed Eng. 2017 04; 45(4):1003-1014. Williams PA, Campbell KT, Gharaviram H, Madrigal JL, Silva EA. PMID: 27904998.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Microfluidic generation of alginate microgels for the controlled delivery of lentivectors. J Mater Chem B. 2016 Nov 21; 4(43):6989-6999. Madrigal JL, Stilhano RS, Siltanen C, Tanaka K, Rezvani SN, Morgan RP, Revzin A, Han SW, Silva EA. PMID: 32263565.
      View in: PubMed   Mentions: 1     Fields:    
    22. Injectable alginate hydrogel for enhanced spatiotemporal control of lentivector delivery in murine skeletal muscle. J Control Release. 2016 09 10; 237:42-9. Stilhano RS, Madrigal JL, Wong K, Williams PA, Martin PK, Yamaguchi FS, Samoto VY, Han SW, Silva EA. PMID: 27374631.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    23. Hydrogel biophysical properties instruct coculture-mediated osteogenic potential. FASEB J. 2016 Jan; 30(1):477-86. Murphy KC, Stilhano RS, Mitra D, Zhou D, Batarni S, Silva EA, Leach JK. PMID: 26443826.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    24. The Role of Synthetic Extracellular Matrices in Endothelial Progenitor Cell Homing for Treatment of Vascular Disease. Ann Biomed Eng. 2015 Oct; 43(10):2301-13. Williams PA, Silva EA. PMID: 26206680.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    25. Lysophosphatidic Acid and Sphingosine-1-Phosphate: A Concise Review of Biological Function and Applications for Tissue Engineering. Tissue Eng Part B Rev. 2015 Dec; 21(6):531-42. Binder BY, Williams PA, Silva EA, Leach JK. PMID: 26035484.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    26. Alginate and DNA Gels Are Suitable Delivery Systems for Diabetic Wound Healing. Int J Low Extrem Wounds. 2015 Jun; 14(2):146-53. Tellechea A, Silva EA, Min J, Leal EC, Auster ME, Pradhan-Nabzdyk L, Shih W, Mooney DJ, Veves A. PMID: 26032947.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    27. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). PLoS One. 2015; 10(4):e0123437. Williams PA, Stilhano RS, To VP, Tran L, Wong K, Silva EA. PMID: 25875493.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    28. Refilling drug delivery depots through the blood. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):12722-7. Brudno Y, Silva EA, Kearney CJ, Lewin SA, Miller A, Martinick KD, Aizenberg M, Mooney DJ. PMID: 25139997.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    29. Endothelial cells expressing low levels of CD143 (ACE) exhibit enhanced sprouting and potency in relieving tissue ischemia. Angiogenesis. 2014 Jul; 17(3):617-30. Silva EA, Eseonu C, Mooney DJ. PMID: 24414940.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    30. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS One. 2013; 8(12):e83755. Shamis Y, Silva EA, Hewitt KJ, Brudno Y, Levenberg S, Mooney DJ, Garlick JA. PMID: 24386271.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    31. Injectable MMP-sensitive alginate hydrogels as hMSC delivery systems. Biomacromolecules. 2014 Jan 13; 15(1):380-90. Fonseca KB, Gomes DB, Lee K, Santos SG, Sousa A, Silva EA, Mooney DJ, Granja PL, Barrias CC. PMID: 24345197.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    32. Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA. Cell Res. 2013 Oct; 23(10):1172-86. Lui KO, Zangi L, Silva EA, Bu L, Sahara M, Li RA, Mooney DJ, Chien KR. PMID: 24018375.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    33. Surface modification with alginate-derived polymers for stable, protein-repellent, long-circulating gold nanoparticles. ACS Nano. 2012 Jun 26; 6(6):4796-805. Kodiyan A, Silva EA, Kim J, Aizenberg M, Mooney DJ. PMID: 22650310.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    34. Guided bone regeneration using injectable vascular endothelial growth factor delivery gel. J Periodontol. 2013 Feb; 84(2):230-8. Kaigler D, Silva EA, Mooney DJ. PMID: 22668339.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    35. Viability and functionality of cells delivered from peptide conjugated scaffolds. Biomaterials. 2011 May; 32(15):3721-8. Vacharathit V, Silva EA, Mooney DJ. PMID: 21334064.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    36. Targeted delivery of nanoparticles to ischemic muscle for imaging and therapeutic angiogenesis. . 2011 Feb 09; 11(2):694-700. Kim J, Cao L, Shvartsman D, Silva EA, Mooney DJ. PMID: 21192718.
      View in: PubMed   Mentions:
    37. Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17933-8. Yuen WW, Du NR, Chan CH, Silva EA, Mooney DJ. PMID: 20921366.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    38. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface. 2011 Feb 06; 8(55):153-70. Lee K, Silva EA, Mooney DJ. PMID: 20719768.
      View in: PubMed   Mentions: 311     Fields:    Translation:Cells
    39. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplant. 2010; 19(9):1063-71. Emerich DF, Silva E, Ali O, Mooney D, Bell W, Yu SJ, Kaneko Y, Borlongan C. PMID: 20412616.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    40. Sustained release of multiple growth factors from injectable polymeric system as a novel therapeutic approach towards angiogenesis. Pharm Res. 2010 Feb; 27(2):264-71. Sun Q, Silva EA, Wang A, Fritton JC, Mooney DJ, Schaffler MB, Grossman PM, Rajagopalan S. PMID: 19953308.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    41. Effects of VEGF temporal and spatial presentation on angiogenesis. Biomaterials. 2010 Feb; 31(6):1235-41. Silva EA, Mooney DJ. PMID: 19906422.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    42. Material-based deployment enhances efficacy of endothelial progenitor cells. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14347-52. Silva EA, Kim ES, Kong HJ, Mooney DJ. PMID: 18794520.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    43. Integrated approach to designing growth factor delivery systems. FASEB J. 2007 Dec; 21(14):3896-903. Chen RR, Silva EA, Yuen WW, Brock AA, Fischbach C, Lin AS, Guldberg RE, Mooney DJ. PMID: 17644610.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    44. Tissue engineering: a glue for biomaterials. Nat Mater. 2007 May; 6(5):327-8. Mooney DJ, Silva EA. PMID: 17471269.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    45. Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction. Cardiovasc Res. 2007 Jul 01; 75(1):178-85. Hao X, Silva EA, Månsson-Broberg A, Grinnemo KH, Siddiqui AJ, Dellgren G, Wärdell E, Brodin LA, Mooney DJ, Sylvén C. PMID: 17481597.
      View in: PubMed   Mentions: 101     Fields:    Translation:Animals
    46. Quantification of lactobionic acid and sorbitol from enzymatic reaction of fructose and lactose by high-performance liquid chromatography. J Chromatogr A. 2007 Mar 23; 1145(1-2):128-32. Pedruzzi I, Malvessi E, Mata VG, Silva EA, Silveira MM, Rodrigues AE. PMID: 17306812.
      View in: PubMed   Mentions: 2     Fields:    
    47. Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis. J Thromb Haemost. 2007 Mar; 5(3):590-8. Silva EA, Mooney DJ. PMID: 17229044.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    48. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res. 2007 Feb; 24(2):258-64. Chen RR, Silva EA, Yuen WW, Mooney DJ. PMID: 17191092.
      View in: PubMed   Mentions: 116     Fields:    Translation:Animals
    49. Synthetic extracellular matrices for tissue engineering and regeneration. Curr Top Dev Biol. 2004; 64:181-205. Silva EA, Mooney DJ. PMID: 15563948.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
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