-
Novel genomic prognostic biomarkers for dogs with cancer. J Vet Intern Med. 2023 Nov-Dec; 37(6):2410-2421.
Chon E, Sakthikumar S, Tang M, Hamilton MJ, Vaughan A, Smith A, Sommer B, Robat C, Manley C, Mullin C, Ohashi E, Manor E, Custis J, Intile J, Shiu KB, Parshley L, Bergman N, Sheppard-Olivares S, Hafeman S, Wright Z, Haworth D, Hendricks W, Wang G. PMID: 37801037; PMCID: PMC10658597.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Successful kinetic impact into an asteroid for planetary defence. Nature. 2023 04; 616(7957):443-447.
Daly RT, Ernst CM, Barnouin OS, Chabot NL, Rivkin AS, Cheng AF, Adams EY, Agrusa HF, Abel ED, Alford AL, Asphaug EI, Atchison JA, Badger AR, Baki P, Ballouz RL, Bekker DL, Bellerose J, Bhaskaran S, Buratti BJ, Cambioni S, Chen MH, Chesley SR, Chiu G, Collins GS, Cox MW, DeCoster ME, Ericksen PS, Espiritu RC, Faber AS, Farnham TL, Ferrari F, Fletcher ZJ, Gaskell RW, Graninger DM, Haque MA, Harrington-Duff PA, Hefter S, Herreros I, Hirabayashi M, Huang PM, Hsieh SW, Jacobson SA, Jenkins SN, Jensenius MA, John JW, Jutzi M, Kohout T, Krueger TO, Laipert FE, Lopez NR, Luther R, Lucchetti A, Mages DM, Marchi S, Martin AC, McQuaide ME, Michel P, Moskovitz NA, Murphy IW, Murdoch N, Naidu SP, Nair H, Nolan MC, Ormö J, Pajola M, Palmer EE, Peachey JM, Pravec P, Raducan SD, Ramesh KT, Ramirez JR, Reynolds EL, Richman JE, Robin CQ, Rodriguez LM, Roufberg LM, Rush BP, Sawyer CA, Scheeres DJ, Scheirich P, Schwartz SR, Shannon MP, Shapiro BN, Shearer CE, Smith EJ, Steele RJ, Steckloff JK, Stickle AM, Sunshine JM, Superfin EA, Tarzi ZB, Thomas CA, Thomas JR, Trigo-Rodríguez JM, Tropf BT, Vaughan AT, Velez D, Waller CD, Wilson DS, Wortman KA, Zhang Y. PMID: 36858073; PMCID: PMC10115643.
View in:
PubMed Mentions:
5 Fields:
-
PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop. iScience. 2022 Dec 22; 25(12):105546.
Alexandrou AT, Duan Y, Xu S, Tepper C, Fan M, Tang J, Berg J, Basheer W, Valicenti T, Wilson PF, Coleman MA, Vaughan AT, Fu L, Grdina DJ, Murley J, Wang A, Woloschak G, Li JJ. PMID: 36465103; PMCID: PMC9708791.
View in:
PubMed Mentions:
2
-
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L341-L354.
Ikonomou L, Magnusson M, Dries R, Herzog EL, Hynds RE, Borok Z, Park JA, Skolasinski S, Burgess JK, Turner L, Mojarad SM, Mahoney JE, Lynch T, Lehmann M, Thannickal VJ, Hook JL, Vaughan AE, Hoffman ET, Weiss DJ, Ryan AL. PMID: 35762622; PMCID: PMC9484991.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCellsPHPublic Health
-
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591.
Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. PMID: 32929084; PMCID: PMC7490264.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
Controlled Human Infection With Bordetella pertussis Induces Asymptomatic, Immunizing Colonization. Clin Infect Dis. 2020 07 11; 71(2):403-411.
de Graaf H, Ibrahim M, Hill AR, Gbesemete D, Vaughan AT, Gorringe A, Preston A, Buisman AM, Faust SN, Kester KE, Berbers GAM, Diavatopoulos DA, Read RC. PMID: 31562530; PMCID: PMC7353841.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCellsCTClinical Trials
-
Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR. Methods Mol Biol. 2020; 2102:271-288.
Singh S, Shih SJ, Vaughan ATM. PMID: 31989561.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer. Front Oncol. 2019; 9:1201.
Han S, Wei R, Zhang X, Jiang N, Fan M, Huang JH, Xie B, Zhang L, Miao W, Butler AC, Coleman MA, Vaughan AT, Wang Y, Chen HW, Liu J, Li JJ. PMID: 31803610; PMCID: PMC6873486.
View in:
PubMed Mentions:
66
-
Protocol for a controlled human infection with genetically modified Neisseria lactamica expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine. BMJ Open. 2019 05 01; 9(4):e026544.
Gbesemete D, Laver JR, de Graaf H, Ibrahim M, Vaughan A, Faust S, Gorringe A, Read RC. PMID: 31048443; PMCID: PMC6501966.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Development of solitary chemosensory cells in the distal lung after severe influenza injury. Am J Physiol Lung Cell Mol Physiol. 2019 06 01; 316(6):L1141-L1149.
Rane CK, Jackson SR, Pastore CF, Zhao G, Weiner AI, Patel NN, Herbert DR, Cohen NA, Vaughan AE. PMID: 30908939; PMCID: PMC6620670.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
-
Treatment outcomes in HPV-negative oropharyngeal cancer: Surgery plus radiotherapy vs. definitive chemoradiotherapy. Ear Nose Throat J. 2018 Aug; 97(8):E1-E7.
Rash D, Daly ME, Durbin-Johnson B, Vaughan AT, Chen AM. PMID: 30138518.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Shaving Is an Epiphenomenon of Type I and II Anti-CD20-Mediated Phagocytosis, whereas Antigenic Modulation Limits Type I Monoclonal Antibody Efficacy. J Immunol. 2018 08 15; 201(4):1211-1221.
Dahal LN, Huang CY, Stopforth RJ, Mead A, Chan K, Bowater JX, Taylor MC, Narang P, Chan HTC, Kim JH, Vaughan AT, Forconi F, Beers SA. PMID: 29997125; PMCID: PMC6082343.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer. Retrovirology. 2017 01 20; 14(1):3.
Miller AD, De Las Heras M, Yu J, Zhang F, Liu SL, Vaughan AE, Vaughan TL, Rosadio R, Rocca S, Palmieri G, Goedert JJ, Fujimoto J, Wistuba II. PMID: 28107820; PMCID: PMC5248497.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCellsPHPublic Health
-
FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells. J Immunol. 2016 09 01; 197(5):1587-96.
Pauls SD, Ray A, Hou S, Vaughan AT, Cragg MS, Marshall AJ. PMID: 27456487.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Influence of nuclear structure on the formation of radiation-induced lethal lesions. Int J Radiat Biol. 2016 05; 92(5):229-40.
Friedman DA, Tait L, Vaughan AT. PMID: 26917327.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Exposure Risks Among Children Undergoing Radiation Therapy: Considerations in the Era of Image Guided Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Apr 01; 94(5):978-92.
Hess CB, Thompson HM, Benedict SH, Seibert JA, Wong K, Vaughan AT, Chen AM. PMID: 27026304.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansPHPublic Health
-
Point/Counterpoint. Spontaneous tumors in pets are an excellent translational model for human cancers. Med Phys. 2015 Nov; 42(11):6127-9.
Sapareto SA, Vaughan AT, Orton CG. PMID: 26520705.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors. J Immunol. 2015 Dec 01; 195(11):5503-16.
Tutt AL, James S, Laversin SA, Tipton TR, Ashton-Key M, French RR, Hussain K, Vaughan AT, Dou L, Earley A, Dahal LN, Lu C, Dunscombe M, Chan HT, Penfold CA, Kim JH, Potter EA, Mockridge CI, Roghanian A, Oldham RJ, Cox KL, Lim SH, Teige I, Frendéus B, Glennie MJ, Beers SA, Cragg MS. PMID: 26512139.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
Antibody modulation: Limiting the efficacy of therapeutic antibodies. Pharmacol Res. 2015 Sep; 99:269-75.
Vaughan AT, Cragg MS, Beers SA. PMID: 26188150.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015 Sep; 14(9):2090-102.
Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, Zou JX, Zhang T, Juma S, Jin C, Li RF, Perks J, Sun LQ, Vaughan AT, Hai CX, Gius DR, Li JJ. PMID: 26141949; PMCID: PMC4560959.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
-
SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells. PLoS One. 2015; 10(6):e0129834.
Cui Y, Qin L, Wu J, Qu X, Hou C, Sun W, Li S, Vaughan AT, Li JJ, Liu J. PMID: 26121691; PMCID: PMC4487898.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo. Cancer Cell. 2015 Apr 13; 27(4):473-88.
Roghanian A, Teige I, Mårtensson L, Cox KL, Kovacek M, Ljungars A, Mattson J, Sundberg A, Vaughan AT, Shah V, Smyth NR, Sheth B, Chan HT, Li ZC, Williams EL, Manfredi G, Oldham RJ, Mockridge CI, James SA, Dahal LN, Hussain K, Nilsson B, Verbeek JS, Juliusson G, Hansson M, Jerkeman M, Johnson PW, Davies A, Beers SA, Glennie MJ, Frendéus B, Cragg MS. PMID: 25873171.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimals
-
CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection. Free Radic Biol Med. 2015 Apr; 81:77-87.
Jin C, Qin L, Shi Y, Candas D, Fan M, Lu CL, Vaughan AT, Shen R, Wu LS, Liu R, Li RF, Murley JS, Woloschak G, Grdina DJ, Li JJ. PMID: 25578653; PMCID: PMC4359946.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
Activatory and inhibitory Fcγ receptors augment rituximab-mediated internalization of CD20 independent of signaling via the cytoplasmic domain. J Biol Chem. 2015 Feb 27; 290(9):5424-37.
Vaughan AT, Chan CH, Klein C, Glennie MJ, Beers SA, Cragg MS. PMID: 25568316; PMCID: PMC4342459.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway. Leuk Lymphoma. 2015 May; 56(5):1460-5.
Wright RL, Slemmons KK, Vaughan AT. PMID: 25130479.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
A systematic description of MLL fusion gene formation. Crit Rev Oncol Hematol. 2014 Sep; 91(3):283-91.
Wright RL, Vaughan AT. PMID: 24787275.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Competing causes of death and medical comorbidities among patients with human papillomavirus-positive vs human papillomavirus-negative oropharyngeal carcinoma and impact on adherence to radiotherapy. JAMA Otolaryngol Head Neck Surg. 2014 Apr; 140(4):312-6.
Hess CB, Rash DL, Daly ME, Farwell DG, Bishop J, Vaughan AT, Wilson MD, Chen AM. PMID: 24526276; PMCID: PMC4397215.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Detection of DNA double-strand breaks and chromosome translocations using ligation-mediated PCR and inverse PCR. Methods Mol Biol. 2014; 1105:399-415.
Singh S, Shih SJ, Vaughan AT. PMID: 24623244.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Inhibitory FcγRIIb (CD32b) becomes activated by therapeutic mAb in both cis and trans and drives internalization according to antibody specificity. Blood. 2014 Jan 30; 123(5):669-77.
Vaughan AT, Iriyama C, Beers SA, Chan CH, Lim SH, Williams EL, Shah V, Roghanian A, Frendéus B, Glennie MJ, Cragg MS. PMID: 24227819.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Definitive radiation therapy without chemotherapy for human papillomavirus-positive head and neck cancer. Head Neck. 2013 Nov; 35(11):1652-6.
Chen AM, Zahra T, Daly ME, Farwell DG, Luu Q, Gandour-Edwards R, Vaughan AT. PMID: 23335285; PMCID: PMC4757483.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Zinc Finger Nuclease induced DNA double stranded breaks and rearrangements in MLL. Mutat Res. 2012 Dec; 740(1-2):34-42.
Do TU, Ho B, Shih SJ, Vaughan A. PMID: 23291497; PMCID: PMC3578303.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress. J Mol Cell Biol. 2013 Jun; 5(3):166-75.
Candas D, Fan M, Nantajit D, Vaughan AT, Murley JS, Woloschak GE, Grdina DJ, Li JJ. PMID: 23243068; PMCID: PMC3656610.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
Differential response rates to irradiation among patients with human papillomavirus positive and negative oropharyngeal cancer. Laryngoscope. 2013 Jan; 123(1):152-7.
Chen AM, Li J, Beckett LA, Zhara T, Farwell G, Lau DH, Gandour-Edwards R, Vaughan AT, Purdy JA. PMID: 23008061.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Multiple clonal MLL fusions in a patient receiving CHOP-based chemotherapy. Br J Haematol. 2012 Oct; 159(1):50-7.
Shih SJ, Fass J, Buffalo V, Lin D, Singh SP, Diaz MO, Vaughan AT. PMID: 22845170; PMCID: PMC3444640.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Localized DNA cleavage secondary to genotoxic exposure adjacent to an Alu inverted repeat. Genes Chromosomes Cancer. 2012 May; 51(5):501-9.
Ho B, Baker PM, Singh S, Shih SJ, Vaughan AT. PMID: 22334386.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy. Blood. 2011 Sep 01; 118(9):2530-40.
Lim SH, Vaughan AT, Ashton-Key M, Williams EL, Dixon SV, Chan HT, Beers SA, French RR, Cox KL, Davies AJ, Potter KN, Mockridge CI, Oscier DG, Johnson PW, Cragg MS, Glennie MJ. PMID: 21768293.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansCells
-
The left half of the XMRV retrovirus is present in an endogenous retrovirus of NIH/3T3 Swiss mouse cells. J Virol. 2011 Sep; 85(17):9247-8.
Mendoza R, Vaughan AE, Miller AD. PMID: 21697491; PMCID: PMC3165791.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Head and neck cancer among lifelong never-smokers and ever-smokers: matched-pair analysis of outcomes after radiation therapy. Am J Clin Oncol. 2011 Jun; 34(3):270-5.
Chen AM, Chen LM, Vaughan A, Farwell DG, Luu Q, Purdy JA, Vijayakumar S. PMID: 20622648.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansPHPublic Health
-
B cells--masters of the immunoverse. Int J Biochem Cell Biol. 2011 Mar; 43(3):280-5.
Vaughan AT, Roghanian A, Cragg MS. PMID: 21147251.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
Androgen Receptor regulation of Vitamin D receptor in response of castration-resistant prostate cancer cells to 1α-Hydroxyvitamin D5 - a calcitriol analog. Genes Cancer. 2010 Nov 16; 1(9):927-940.
Mooso B, Madhav A, Johnson S, Roy M, Moore ME, Moy C, Loredo GA, Mehta RG, Vaughan AT, Ghosh PM. PMID: 21552398; PMCID: PMC3089062.
View in:
PubMed Mentions:
11
-
11q21.1-11q23.3 Is a site of intrinsic genomic instability triggered by irradiation. Genes Chromosomes Cancer. 2010 Sep; 49(9):831-43.
Du N, Baker PM, Do TU, Bien C, Bier-Laning CM, Singh S, Shih SJ, Diaz MO, Vaughan AT. PMID: 20607707; PMCID: PMC2921793.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Neisseria lactamica selectively induces mitogenic proliferation of the naive B cell pool via cell surface Ig. J Immunol. 2010 Sep 15; 185(6):3652-60.
Vaughan AT, Brackenbury LS, Massari P, Davenport V, Gorringe A, Heyderman RS, Williams NA. PMID: 20709949.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Tobacco smoking during radiation therapy for head-and-neck cancer is associated with unfavorable outcome. Int J Radiat Oncol Biol Phys. 2011 Feb 01; 79(2):414-9.
Chen AM, Chen LM, Vaughan A, Sreeraman R, Farwell DG, Luu Q, Lau DH, Stuart K, Purdy JA, Vijayakumar S. PMID: 20399030.
View in:
PubMed Mentions:
78 Fields:
Translation:
Humans
-
Primary radiation therapy for head-and-neck cancer in the setting of human immunodeficiency virus. Int J Radiat Oncol Biol Phys. 2011 Jan 01; 79(1):60-4.
Klein EA, Guiou M, Farwell DG, Luu Q, Lau DH, Stuart K, Vaughan A, Vijayakumar S, Chen AM. PMID: 20385454.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Suberoylanilide hydroxyamic acid modification of chromatin architecture affects DNA break formation and repair. Int J Radiat Oncol Biol Phys. 2010 Feb 01; 76(2):566-73.
Singh S, Le H, Shih SJ, Ho B, Vaughan AT. PMID: 20117292; PMCID: PMC2818091.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Rearrangements of the MLL gene are influenced by DNA secondary structure, potentially mediated by topoisomerase II binding. Genes Chromosomes Cancer. 2009 Sep; 48(9):806-15.
Le H, Singh S, Shih SJ, Du N, Schnyder S, Loredo GA, Bien C, Michaelis L, Toor A, Diaz MO, Vaughan AT. PMID: 19530238; PMCID: PMC2764312.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Estrogen treatment induces MLL aberrations in human lymphoblastoid cells. Leuk Res. 2009 Oct; 33(10):1400-4.
Schnyder S, Du NT, Le HB, Singh S, Loredo GA, Vaughan AT. PMID: 19264358; PMCID: PMC2758092.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage. J Immunol. 2009 Feb 15; 182(4):2231-40.
Vaughan AT, Gorringe A, Davenport V, Williams NA, Heyderman RS. PMID: 19201877.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Palliative radiation therapy for head and neck cancer: toward an optimal fractionation scheme. Head Neck. 2008 Dec; 30(12):1586-91.
Chen AM, Vaughan A, Narayan S, Vijayakumar S. PMID: 18798313.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Impaired NHEJ function in multiple myeloma. Mutat Res. 2009 Jan 15; 660(1-2):66-73.
Yang C, Betti C, Singh S, Toor A, Vaughan A. PMID: 19028508; PMCID: PMC2875794.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
NASA Radiation Biomarker Workshop, September 27-28, 2007. Radiat Res. 2008 Sep; 170(3):393-405.
Straume T, Amundson SA, Blakely WF, Burns FJ, Chen A, Dainiak N, Franklin S, Leary JA, Loftus DJ, Morgan WF, Pellmar TC, Stolc V, Turteltaub KW, Vaughan AT, Vijayakumar S, Wyrobek AJ. PMID: 18763867.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Prospective evaluation to establish a dose response for clinical oral mucositis in patients undergoing head-and-neck conformal radiotherapy. Int J Radiat Oncol Biol Phys. 2008 Nov 01; 72(3):756-62.
Narayan S, Lehmann J, Coleman MA, Vaughan A, Yang CC, Enepekides D, Farwell G, Purdy JA, Laredo G, Nolan K, Pearson FS, Vijayakumar S. PMID: 18417299.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. Blood. 2007 Dec 15; 110(13):4427-35.
Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. PMID: 17804695; PMCID: PMC2234793.
View in:
PubMed Mentions:
167 Fields:
Translation:
HumansAnimalsCells
-
Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis. J Immunol. 2006 May 15; 176(10):5863-70.
Xin H, D'Souza S, Jørgensen TN, Vaughan AT, Lengyel P, Kotzin BL, Choubey D. PMID: 16670293.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Detection of DNA double-strand breaks and chromosome translocations using ligation-mediated PCR and inverse PCR. Methods Mol Biol. 2006; 314:109-21.
Villalobos MJ, Betti CJ, Vaughan AT. PMID: 16673878.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activity. Leukemia. 2005 Dec; 19(12):2289-95.
Betti CJ, Villalobos MJ, Jiang Q, Cline E, Diaz MO, Loredo G, Vaughan AT. PMID: 16193084.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Surviving apoptosis: a possible mechanism of benzene-induced leukemia. Chem Biol Interact. 2005 May 30; 153-154:179-85.
Vaughan AT, Betti CJ, Villalobos MJ, Premkumar K, Cline E, Jiang Q, Diaz MO. PMID: 15935815.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Detection of DNA double-strand breaks and chromosome translocations using ligation-mediated PCR and inverse PCR. Methods Mol Biol. 2005; 291:279-89.
Villalobos MJ, Betti CJ, Vaughan AT. PMID: 15502230.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division. Cancer Res. 2003 Mar 15; 63(6):1377-81.
Betti CJ, Villalobos MJ, Diaz MO, Vaughan AT. PMID: 12649202.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Surviving apoptosis. Apoptosis. 2002 Apr; 7(2):173-7.
Vaughan AT, Betti CJ, Villalobos MJ. PMID: 11865202.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
Steroid-mediated inhibition of radiation-induced apoptosis in C4-1 cervical carcinoma cells is p53-dependent. Eur J Cancer. 2001 Nov; 37(17):2240-6.
Kamradt MC, Walter S, Koudelik J, Shafer L, Weijzen S, Velders M, Vaughan AT. PMID: 11677114.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Apoptotic triggers initiate translocations within the MLL gene involving the nonhomologous end joining repair system. Cancer Res. 2001 Jun 01; 61(11):4550-5.
Betti CJ, Villalobos MJ, Diaz MO, Vaughan AT. PMID: 11389089.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansCells
-
LINE L1 retrotransposable element is targeted during the initial stages of apoptotic DNA fragmentation. J Cell Biochem. 2000 Sep 07; 79(3):486-95.
Khodarev NN, Bennett T, Shearing N, Sokolova I, Koudelik J, Walter S, Villalobos M, Vaughan AT. PMID: 10972985.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7. Br J Cancer. 2000 May; 82(10):1709-16.
Kamradt MC, Mohideen N, Krueger E, Walter S, Vaughan AT. PMID: 10817508; PMCID: PMC2374500.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
RU486 increases radiosensitivity and restores apoptosis through modulation of HPV E6/E7 in dexamethasone-treated cervical carcinoma cells. Gynecol Oncol. 2000 Apr; 77(1):177-82.
Kamradt MC, Mohideen N, Vaughan AT. PMID: 10739708.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
P53 overexpression is associated with bulky tumor and poor local control in T1 glottic cancer. Int J Radiat Oncol Biol Phys. 2000 Jan 01; 46(1):21-6.
Narayana A, Vaughan AT, Kathuria S, Fisher SG, Walter SA, Reddy SP. PMID: 10656367.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
-
Abortive apoptosis as an initiator of chromosomal translocations. Med Hypotheses. 1999 May; 52(5):373-6.
Khodarev NN, Sokolova IA, Vaughan AT. PMID: 10416942.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Measurement of low-frequency DNA breaks using nucleoid flow cytometry. Methods Mol Biol. 1999; 113:519-26.
Vaughan AT, Walter S, Milner AE. PMID: 10443447.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Mycoplasma infection can sensitize host cells to apoptosis through contribution of apoptotic-like endonuclease(s). Immunol Cell Biol. 1998 Dec; 76(6):526-34.
Sokolova IA, Vaughan AT, Khodarev NN. PMID: 9893030.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Second primary tumors in laryngeal cancer: results of long-term follow-up. Int J Radiat Oncol Biol Phys. 1998 Oct 01; 42(3):557-62.
Narayana A, Vaughan AT, Fisher SG, Reddy SP. PMID: 9806515.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Association between DNA cleavage during apoptosis and regions of chromatin replication. J Cell Biochem. 1998 Sep 15; 70(4):604-15.
Khodarev NN, Sokolova IA, Vaughan AT. PMID: 9712157.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Synchronous block in DNA synthesis initiation with change in chromatin topology mediated by VP16. DNA Cell Biol. 1998 Jul; 17(7):613-9.
Narayana A, Khodarev N, Walter S, Vaughan AT. PMID: 9703020.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Transfection of a vector expressing wild-type p53 into cells of two human glioma cell lines enhances radiation toxicity. Radiat Res. 1998 Jul; 150(1):31-7.
Geng L, Walter S, Melian E, Vaughan AT. PMID: 9650599.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Mechanisms of induction of apoptotic DNA fragmentation. Int J Radiat Biol. 1998 May; 73(5):455-67.
Khodarev NN, Sokolova IA, Vaughan AT. PMID: 9652802.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
Multiple forms of endonuclease activity linked with radiation induced apoptosis in C4-1 cervical carcinoma cells. Anticancer Res. 1998 Mar-Apr; 18(2A):983-8.
Krueger E, Sokolova I, Kamradt M, Khodarev NN, Vaughan AT. PMID: 9615751.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Is p53 an independent prognostic factor in patients with laryngeal carcinoma? Cancer. 1998 Jan 15; 82(2):286-91.
Narayana A, Vaughan AT, Gunaratne S, Kathuria S, Walter SA, Reddy SP. PMID: 9445184.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
-
Differential effects of BCL-2 on survival and proliferation of human B-lymphoma cells following gamma-irradiation. Oncogene. 1997 Oct 09; 15(15):1815-22.
Milner AE, Grand RJ, Vaughan AT, Armitage RJ, Gregory CD. PMID: 9362448.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Topologically constrained domains of supercoiled DNA in eukaryotic cells. DNA Cell Biol. 1997 Sep; 16(9):1051-8.
Khodarev NN, Narayana A, Constantinou A, Vaughan AT. PMID: 9324307.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Flow cytometry assay for rapid analysis of DNA strand breaks. Cytotechnology. 1997 Sep 1; 19(3):221-225.
Narayana NA, Walter WS, Vaughan VA. .
View in:
Publisher Site Mentions:
-
Interferon-gamma enhances susceptibility of cervical cancer cells to lysis by tumor-specific cytotoxic T cells. Gynecol Oncol. 1997 May; 65(2):265-72.
Street D, Kaufmann AM, Vaughan A, Fisher SG, Hunter M, Schreckenberger C, Potkul RK, Gissmann L, Qiao L. PMID: 9159336.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res. 1996 Nov-Dec; 16(6A):3293-8.
Constantinou AI, Mehta RG, Vaughan A. PMID: 9042303.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Commitment to erythroid differentiation in mouse erythroleukemia cells is controlled by alterations in topoisomerase II alpha phosphorylation. Cancer Res. 1996 Sep 15; 56(18):4192-9.
Constantinou AI, Vaughan AT, Yamasaki H, Kamath N. PMID: 8797591.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Paclitaxel is only a weak radiosensitizer of human cervical carcinoma cell lines. Gynecol Oncol. 1996 Feb; 60(2):251-4.
Erlich E, McCall AR, Potkul RK, Walter S, Vaughan A. PMID: 8631547.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Stimulation of a Ca(2+)-calmodulin-activated histone 3 arginine kinase in quiescent rat heart endothelial cells compared to actively dividing cells. J Biol Chem. 1995 Sep 29; 270(39):23155-8.
Wakim BT, Grutkoski PS, Vaughan AT, Engelmann GL. PMID: 7559461.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status. Mutat Res. 1995 Feb; 346(2):85-92.
Zhen W, Denault CM, Loviscek K, Walter S, Geng L, Vaughan AT. PMID: 7885404.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Effect of caffeine on radiation-induced apoptosis in TK6 cells. Radiat Res. 1995 Feb; 141(2):170-5.
Zhen W, Vaughan AT. PMID: 7838955.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships. J Nat Prod. 1995 Feb; 58(2):217-25.
Constantinou A, Mehta R, Runyan C, Rao K, Vaughan A, Moon R. PMID: 7769390.
View in:
PubMed Mentions:
48 Fields:
Translation:
Cells
-
Local control of T2/3 transitional cell carcinoma of bladder is correlated to differences in DNA supercoiling: evidence for two discrete tumor populations. Cancer Res. 1993 May 15; 53(10 Suppl):2300-3.
Vaughan AT, Anderson P, Wallace DM, Beaney RP, Lynch TH. PMID: 8485715.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCellsCTClinical Trials
-
Metaphase chromosome and nucleoid differences between CHO-K1 and its radiosensitive derivative xrs-5. Mutagenesis. 1993 Mar; 8(2):105-8.
Schwartz JL, Cowen JM, Moan E, Sedita BA, Stephens J, Vaughan AT. PMID: 8464379.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
DNA-nuclear matrix interactions and ionizing radiation sensitivity. Environ Mol Mutagen. 1993; 22(4):231-3.
Schwartz JL, Vaughan AT. PMID: 8223503.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
A correlation between DNA-nuclear matrix binding and relative radiosensitivity in two human squamous cell carcinoma cell lines. Int J Radiat Biol. 1993 Jan; 63(1):13-20.
Milner AE, Gordon DJ, Turner BM, Vaughan AT. PMID: 8093463.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Hydrogen peroxide lethality is associated with a decreased ability to maintain positive DNA supercoiling. Exp Cell Res. 1992 Oct; 202(2):376-80.
Vaughan AT, Gordon DJ. PMID: 1397090.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
A correlation between nuclear supercoiling and the response of patients with bladder cancer to radiotherapy. Br J Cancer. 1991 Nov; 64(5):867-71.
Lynch TH, Anderson P, Wallace DM, Kondratowicz GM, Beaney RP, Vaughan AT. PMID: 1931607; PMCID: PMC1977490.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Interaction between ionizing radiation and supercoiled DNA within human tumor cells. Cancer Res. 1991 Aug 01; 51(15):3857-61.
Vaughan AT, Milner AM, Gordon DG, Schwartz JL. PMID: 1855203.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Neutron and cobalt-60 gamma irradiation produce similar changes in DNA supercoiling. Radiat Res. 1991 Jul; 127(1):19-23.
Vaughan AT, Gordon DJ, Chettle DR, Green S. PMID: 2068267.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Association of WR-1065 with CHO AA8 cells, nuclei, and nucleoids. Radiat Res. 1991 Feb; 125(2):152-7.
Meechan PJ, Vaughan AT, Giometti CS, Grdina DJ. PMID: 1996372.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Analysis of free radical damage within single cells using flow cytometry. Mol Aspects Med. 1991; 12(2):129-35.
Vaughan AT, Allan IM, Gordon DJ, Grdina DJ, Milner AM. PMID: 1712885.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Cellular radiosensitivity in V79 cells is linked to alterations in chromatin structure. Int J Radiat Oncol Biol Phys. 1990 Nov; 19(5):1199-201.
Gordon DJ, Milner AE, Beaney RP, Grdina DJ, Vaughan AT. PMID: 2254112.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
The increase in radioresistance of Chinese hamster cells cultured as spheroids is correlated to changes in nuclear morphology. Radiat Res. 1990 Feb; 121(2):175-9.
Gordon DJ, Milner AE, Beaney RP, Grdina DJ, Vaughan AT. PMID: 2305035.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Association between radiation sensitivity, DNA repair and chromosome organization in the Chinese hamster ovary cell line xrs-5. Prog Clin Biol Res. 1990; 340A:255-64.
Schwartz JL, Shadley JD, Jaffe DR, Whitlock J, Rotmensch J, Cowan JM, Gordon DJ, Vaughan AT. PMID: 2388914.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
The role of leucocytes in the induction of fluid secretion by Salmonella typhimurium. J Med Microbiol. 1990 Jan; 31(1):27-35.
Wallis TS, Vaughan AT, Clarke GJ, Qi GM, Worton KJ, Candy DC, Osborne MP, Stephen J. PMID: 2404124.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065. Br J Cancer. 1989 Dec; 60(6):893-6.
Vaughan AT, Grdina DJ, Meechan PJ, Milner AE, Gordon DJ. PMID: 2605099; PMCID: PMC2247278.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Association among DNA/chromosome break rejoining rates, chromatin structure alterations, and radiation sensitivity in human tumor cell lines. Cancer Res. 1989 Sep 15; 49(18):5054-7.
Schwartz JL, Vaughan AT. PMID: 2766277.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Yttrium-90-EDTMP: a radiotherapeutic agent in the treatment of leukaemias. Br J Cancer. 1989 Jul; 60(1):74-8.
Keeling AA, Vaughan AT, Beaney RP. PMID: 2803919; PMCID: PMC2247361.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
The use of flow cytometry in the detection of radiation- and chemically induced nuclear damage in human mononuclear cells. Mutagenesis. 1989 Jan; 4(1):35-8.
Gordon DJ, Milner AE, Vaughan AT, Chipman JK. PMID: 2469939.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Structural damage to lymphocyte nuclei by H2O2 or gamma irradiation is dependent on the mechanism of OH. radical production. Br J Cancer. 1988 Jul; 58(1):34-7.
Allan IM, Vaughan AT, Milner AE, Lunec J, Bacon PA. PMID: 3166891; PMCID: PMC2246489.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Antibodies labeled with 199Au: potential of 199Au for radioimmunotherapy. Int J Rad Appl Instrum B. 1988; 15(3):293-7.
Anderson P, Vaughan AT, Varley NR. PMID: 3384677.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Limitations to the killing of tumours using radiolabelled antibodies. Br J Radiol. 1987 Jun; 60(714):567-72.
Vaughan AT, Anderson P, Dykes PW, Chapman CE, Bradwell AR. PMID: 3620814.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Radioimmunotherapy of cancer: clinical studies and limiting factors. Cancer Treat Rev. 1987 Jun; 14(2):87-106.
Dykes PW, Bradwell AR, Chapman CE, Vaughan AT. PMID: 3315201.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Measurement of DNA damage in mammalian cells using flow cytometry. Radiat Res. 1987 Apr; 110(1):108-17.
Milner AE, Vaughan AT, Clark IP. PMID: 3562788.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Antibodies labeled with metallic radionuclides: influence of nuclide chemistry on dose distribution. NCI Monogr. 1987; (3):141-4.
Vaughan AT, Yankuba SC, Anderson P. PMID: 3029601.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Limitations in localising and killing tumours using radiolabelled antibodies. Nuklearmedizin. 1986 Dec; 25(6):245-8.
Bradwell AR, Vaughan AT, Dykes PW. PMID: 3808966.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Antibody-targeted therapy of cancer. Lancet. 1986 Oct 11; 2(8511):860.
Vaughan A, Chapman C, Dykes PW, Anderson P, Bradwell AR. PMID: 2876299.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Illusions of tumour killing using radiolabelled antibodies. Lancet. 1986 Jun 28; 1(8496):1492-3.
Vaughan AT, Bradwell AR, Dykes PW, Anderson P. PMID: 2873294.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
The production and biological distribution of yttrium-90 labelled antibodies. Int J Appl Radiat Isot. 1985 Oct; 36(10):803-6.
Vaughan AT, Keeling A, Yankuba SC. PMID: 4055089.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Improved tumour localisation using indium-111 labelled antibodies. Br Med J (Clin Res Ed). 1983 Jul 16; 287(6386):167-70.
Fairweather DS, Bradwell AR, Dykes PW, Vaughan AT, Watson-James SF, Chandler S. PMID: 6409238; PMCID: PMC1548673.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Synthesis of cathepsin B by cells derived from the HL60 promyelocytic leukaemia cell line. J Cell Physiol. 1983 Jun; 115(3):249-54.
Burnett D, Crocker J, Vaughan AT. PMID: 6343405.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Improved radioimmunodetection of tumours using second antibody. Lancet. 1983 Jan 29; 1(8318):247.
Bradwell AR, Vaughan A, Fairweather DS, Dykes PW. PMID: 6130282.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Tumour localisation of 211At-labelled monoclonal antibody to a sub-cutaneous human heterograft in the nude mouse II. Int J Nucl Med Biol. 1983; 10(4):241-4.
Bateman WJ, Vaughan AT, Brown G. PMID: 6582053.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
The in vivo fate of a 211At labelled monoclonal antibody with known specificity in a murine system. Int J Radiat Oncol Biol Phys. 1982 Nov; 8(11):1943-6.
Vaughan AT, Bateman WJ, Fisher DR. PMID: 6295988.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
The specific inhibition of cellular clonogenic proliferation using 211At labelled lectins and antibodies--I. Int J Nucl Med Biol. 1982; 9(3):167-71.
Vaughan AT, Bateman WJ, Brown G, Cowan J. PMID: 6957405.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Mice treated with strontium 90: an animal model deficient in NK cells. Br J Cancer. 1981 Aug; 44(2):160-5.
Emmanuel FX, Vaughan AT, Catty D. PMID: 7272185; PMCID: PMC2010750.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
The preparation of astatine labelled proteins using an electrophilic reaction. Int J Nucl Med Biol. 1978; 5(6):229-30.
Vaughan AT, Fremlin JH. PMID: 104931.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals