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Stanley H Benedict

Title(s)Professor, Radiation Oncology
SchoolUniversity of California, Davis
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    RADIOBIOLOGICAL DOSIMETRY OF STEREOTACTIC RADIOSURGERY
    NIH/NCI R29CA076439Sep 4, 1998 - Aug 31, 2003
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shi L, Rong Y, Daly M, Dyer B, Benedict S, Qiu J, Yamamoto T. Cone-beam computed tomography-based delta-radiomics for early response assessment in radiotherapy for locally advanced lung cancer. Phys Med Biol. 2020 Jan 10; 65(1):015009. PMID: 31307024.
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    2. Yuan N, Dyer B, Rao S, Chen Q, Benedict S, Shang L, Kang Y, Qi J, Rong Y. Convolutional neural network enhancement of fast-scan low-dose cone-beam CT images for head and neck radiotherapy. Phys Med Biol. 2019 Dec 16. PMID: 31842014.
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    3. Yuan Z, Rong Y, Benedict SH, Daly ME, Qiu J, Yamamoto T. "Dose of the day" based on cone beam computed tomography and deformable image registration for lung cancer radiotherapy. J Appl Clin Med Phys. 2020 Jan; 21(1):88-94. PMID: 31816170.
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    4. He Y, Rong Y, Chen H, Zhang Z, Qiu J, Zheng L, Benedict S, Niu X, Pan N, Liu Y, Yuan Z. Impact of different b-value combinations on radiomics features of apparent diffusion coefficient in cervical cancer. Acta Radiol. 2019 Aug 29; 284185119870157. PMID: 31466457.
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    5. Dyer BA, Yuan Z, Qiu J, Benedict SH, Valicenti RK, Mayadev JS, Rong Y. Factors associated with deformation accuracy and modes of failure for MRI-optimized cervical brachytherapy using deformable image registration. Brachytherapy. 2019 May - Jun; 18(3):378-386. PMID: 30745016.
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    6. Nie K, Al-Hallaq H, Li XA, Benedict SH, Sohn JW, Moran JM, Fan Y, Huang M, Knopp MV, Michalski JM, Monroe J, Obcemea C, Tsien CI, Solberg T, Wu J, Xia P, Xiao Y, El Naqa I. NCTN Assessment on Current Applications of Radiomics in Oncology. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):302-315. PMID: 30711529.
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    7. Yamamoto T, Kabus S, Bal M, Bzdusek K, Keall PJ, Wright C, Benedict SH, Daly ME. Changes in Regional Ventilation During Treatment and Dosimetric Advantages of CT Ventilation Image Guided Radiation Therapy for Locally Advanced Lung Cancer. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1366-1373. PMID: 29891207.
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    8. Mayadev J, Klapheke A, Yashar C, Hsu IC, Kamrava M, Mundt AJ, Mell LK, Einck J, Benedict S, Valicenti R, Cress R. Underutilization of brachytherapy and disparities in survival for patients with cervical cancer in California. Gynecol Oncol. 2018 07; 150(1):73-78. PMID: 29709291.
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    9. McNutt TR, Benedict SH, Low DA, Moore K, Shpitser I, Jiang W, Lakshminarayanan P, Cheng Z, Han P, Hui X, Nakatsugawa M, Lee J, Moore JA, Robertson SP, Shah V, Taylor R, Quon H, Wong J, DeWeese T. Using Big Data Analytics to Advance Precision Radiation Oncology. Int J Radiat Oncol Biol Phys. 2018 06 01; 101(2):285-291. PMID: 29726357.
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    10. Yuan Z, Nair CK, Benedict SH, Valicenti RK, Rao S, Fragoso RC, Wright C, Qiu J, Rong Y. Converting Treatment Plans From Helical Tomotherapy to L-Shape Linac: Clinical Workflow and Dosimetric Evaluation. Technol Cancer Res Treat. 2018 01 01; 17:1533033818785279. PMID: 29986638.
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    11. Shi L, He Y, Yuan Z, Benedict S, Valicenti R, Qiu J, Rong Y. Radiomics for Response and Outcome Assessment for Non-Small Cell Lung Cancer. Technol Cancer Res Treat. 2018 01 01; 17:1533033818782788. PMID: 29940810.
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    12. Hoffman D, Chung E, Hess C, Stern R, Benedict S. Characterization and evaluation of an integrated quality monitoring system for online quality assurance of external beam radiation therapy. J Appl Clin Med Phys. 2017 Jan; 18(1):40-48. PMID: 28291937.
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    13. Michaud AL, Benedict S, Montemayor E, Hunt JP, Wright C, Mathai M, Mayadev JS. Workflow efficiency for the treatment planning process in CT-guided high-dose-rate brachytherapy for cervical cancer. Brachytherapy. 2016 Sep-Oct; 15(5):578-83. PMID: 27476646.
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    14. Benedict SH, El Naqa I, Klein EE. Introduction to Big Data in Radiation Oncology: Exploring Opportunities for Research, Quality Assessment, and Clinical Care. Int J Radiat Oncol Biol Phys. 2016 07 01; 95(3):871-872. PMID: 27302502.
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    15. Benedict SH, Hoffman K, Martel MK, Abernethy AP, Asher AL, Capala J, Chen RC, Chera B, Couch J, Deye J, Efstathiou JA, Ford E, Fraass BA, Gabriel PE, Huser V, Kavanagh BD, Khuntia D, Marks LB, Mayo C, McNutt T, Miller RS, Moore KL, Prior F, Roelofs E, Rosenstein BS, Sloan J, Theriault A, Vikram B. Overview of the American Society for Radiation Oncology-National Institutes of Health-American Association of Physicists in Medicine Workshop 2015: Exploring Opportunities for Radiation Oncology in the Era of Big Data. Int J Radiat Oncol Biol Phys. 2016 07 01; 95(3):873-879. PMID: 27302503.
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    16. Tait LM, Hoffman D, Benedict S, Valicenti R, Mayadev JS. The use of MRI deformable image registration for CT-based brachytherapy in locally advanced cervical cancer. Brachytherapy. 2016 May-Jun; 15(3):333-340. PMID: 26882845.
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    17. Hess CB, Thompson HM, Benedict SH, Seibert JA, Wong K, Vaughan AT, Chen AM. Exposure Risks Among Children Undergoing Radiation Therapy: Considerations in the Era of Image Guided Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016 Apr 01; 94(5):978-92. PMID: 27026304.
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    18. Yamamoto T, Kabus S, Bal M, Keall P, Benedict S, Daly M. The first patient treatment of computed tomography ventilation functional image-guided radiotherapy for lung cancer. Radiother Oncol. 2016 Feb; 118(2):227-31. PMID: 26687903.
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    19. Chetty IJ, Martel MK, Jaffray DA, Benedict SH, Hahn SM, Berbeco R, Deye J, Jeraj R, Kavanagh B, Krishnan S, Lee N, Low DA, Mankoff D, Marks LB, Ollendorf D, Paganetti H, Ross B, Siochi RA, Timmerman RD, Wong JW. Technology for Innovation in Radiation Oncology. Int J Radiat Oncol Biol Phys. 2015 Nov 01; 93(3):485-92. PMID: 26460989.
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    20. Chen AM, Yu Y, Daly ME, Farwell DG, Benedict SH, Purdy JA. Long-term experience with reduced planning target volume margins and intensity-modulated radiotherapy with daily image-guidance for head and neck cancer. Head Neck. 2014 Dec; 36(12):1766-72. PMID: 24174221.
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    21. Mayadev J, Qi L, Lentz S, Benedict S, Courquin J, Dieterich S, Mathai M, Stern R, Valicenti R. Implant time and process efficiency for CT-guided high-dose-rate brachytherapy for cervical cancer. Brachytherapy. 2014 May-Jun; 13(3):233-9. PMID: 24559793.
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    22. Chen AM, Daly ME, Cui J, Mathai M, Benedict S, Purdy JA. Clinical outcomes among patients with head and neck cancer treated by intensity-modulated radiotherapy with and without adaptive replanning. Head Neck. 2014 Nov; 36(11):1541-6. PMID: 23996502.
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    23. Schlesinger D, Benedict S, Diederich C, Gedroyc W, Klibanov A, Larner J. MR-guided focused ultrasound surgery, present and future. Med Phys. 2013 Aug; 40(8):080901. PMID: 23927296.
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    24. Dunlap NE, Yang W, McIntosh A, Sheng K, Benedict SH, Read PW, Larner JM. Computed tomography-based anatomic assessment overestimates local tumor recurrence in patients with mass-like consolidation after stereotactic body radiotherapy for early-stage non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2012 Dec 01; 84(5):1071-7. PMID: 22898383.
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    25. Wijesooriya K, Aliotta E, Benedict S, Read P, Rich T, Larner J. RapidArc patient specific mechanical delivery accuracy under extreme mechanical limits using linac log files. Med Phys. 2012 Apr; 39(4):1846-53. PMID: 22482606.
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    26. Baisden JM, Sheehan J, Reish AG, McIntosh AF, Sheng K, Read PW, Benedict SH, Larner JM. Helical tomotherapy simultaneous integrated boost provides a dosimetric advantage in the treatment of primary intracranial tumors. Neurol Res. 2011 Oct; 33(8):820-4. PMID: 22004704.
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    27. Solberg TD, Balter JM, Benedict SH, Fraass BA, Kavanagh B, Miyamoto C, Pawlicki T, Potters L, Yamada Y. Quality and safety considerations in stereotactic radiosurgery and stereotactic body radiation therapy: Executive summary. Pract Radiat Oncol. 2012 Jan-Mar; 2(1):2-9. PMID: 25740120.
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    28. Yang W, Jones R, Lu W, Geesey C, Benedict S, Read P, Larner J, Sheng K. Feasibility of non-coplanar tomotherapy for lung cancer stereotactic body radiation therapy. Technol Cancer Res Treat. 2011 Aug; 10(4):307-15. PMID: 21728387.
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    29. Benedict SH, De Meerleer G, Orton CG, Stancanello J. Point/counterpoint. High intensity focused ultrasound may be superior to radiation therapy for the treatment of early stage prostate cancer. Med Phys. 2011 Jul; 38(7):3909-12. PMID: 21858986.
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    30. McIntosh A, Shoushtari AN, Benedict SH, Read PW, Wijesooriya K. Quantifying the reproducibility of heart position during treatment and corresponding delivered heart dose in voluntary deep inhalation breath hold for left breast cancer patients treated with external beam radiotherapy. Int J Radiat Oncol Biol Phys. 2011 Nov 15; 81(4):e569-76. PMID: 21531087.
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    31. Cai J, McLawhorn R, Altes TA, de Lange E, Read PW, Larner JM, Benedict SH, Sheng K. Helical tomotherapy planning for lung cancer based on ventilation magnetic resonance imaging. Med Dosim. 2011; 36(4):389-96. PMID: 21377866.
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    32. Sheehan J, Benedict S, Schlesinger D. Brain dose with stereotactic radiosurgery. J Neurosurg. 2011 Jun; 114(6):1578-9; discussion 1579. PMID: 21375375.
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    33. Yang W, Jones R, Read P, Benedict S, Sheng K. Standardized evaluation of simultaneous integrated boost plans on volumetric modulated arc therapy. Phys Med Biol. 2011 Jan 21; 56(2):327-39. PMID: 21160109.
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    34. Cai J, Yue J, McLawhorn R, Yang W, Wijesooriya K, Dunlap NE, Sheng K, Yin FF, Benedict SH. Dosimetric comparison of 6 MV and 15 MV single arc rapidarc to helical TomoTherapy for the treatment of pancreatic cancer. Med Dosim. 2011; 36(3):317-20. PMID: 20846850.
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    35. Benedict SH, Yenice KM, Followill D, Galvin JM, Hinson W, Kavanagh B, Keall P, Lovelock M, Meeks S, Papiez L, Purdie T, Sadagopan R, Schell MC, Salter B, Schlesinger DJ, Shiu AS, Solberg T, Song DY, Stieber V, Timmerman R, Tomé WA, Verellen D, Wang L, Yin FF. Stereotactic body radiation therapy: the report of AAPM Task Group 101. Med Phys. 2010 Aug; 37(8):4078-101. PMID: 20879569.
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    36. Cai J, McLawhorn R, Read PW, Larner JM, Yin FF, Benedict SH, Sheng K. Effects of breathing variation on gating window internal target volume in respiratory gated radiation therapy. Med Phys. 2010 Aug; 37(8):3927-34. PMID: 20879555.
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    37. Dunlap N, McIntosh A, Sheng K, Yang W, Turner B, Shoushtari A, Sheehan J, Jones DR, Lu W, Ruchala K, Olivera G, Parnell D, Larner JL, Benedict SH, Read PW. Helical tomotherapy-based STAT stereotactic body radiation therapy: Dosimetric evaluation for a real-time SBRT treatment planning and delivery program. Med Dosim. 2010; 35(4):312-9. PMID: 21055611.
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    38. Yang W, Wang L, Larner J, Read P, Benedict S, Sheng K. Tumor cell survival dependence on helical tomotherapy, continuous arc and segmented dose delivery. Phys Med Biol. 2009 Nov 07; 54(21):6635-43. PMID: 19826199.
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    39. Zhong X, Meyer CH, Schlesinger DJ, Sheehan JP, Epstein FH, Larner JM, Benedict SH, Read PW, Sheng K, Cai J. Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI. Med Phys. 2009 Aug; 36(8):3413-9. PMID: 19746774.
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    40. Cai J, Sheng K, Benedict SH, Read PW, Larner JM, Mugler JP, de Lange EE, Cates GD, Miller GW. Dynamic MRI of grid-tagged hyperpolarized helium-3 for the assessment of lung motion during breathing. Int J Radiat Oncol Biol Phys. 2009 Sep 01; 75(1):276-84. PMID: 19540059.
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    41. Dunlap NE, Cai J, Biedermann GB, Yang W, Benedict SH, Sheng K, Schefter TE, Kavanagh BD, Larner JM. Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3):796-801. PMID: 19427740.
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    42. Yang W, Van Ausdal R, Read P, Larner J, Benedict S, Sheng K. The implication of non-cyclic intrafractional longitudinal motion in SBRT by TomoTherapy. Phys Med Biol. 2009 May 07; 54(9):2875-84. PMID: 19384001.
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    43. Cai J, Read PW, Larner JM, Jones DR, Benedict SH, Sheng K. Reproducibility of interfraction lung motion probability distribution function using dynamic MRI: statistical analysis. Int J Radiat Oncol Biol Phys. 2008 Nov 15; 72(4):1228-35. PMID: 18954717.
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    44. Benedict SH, Bova FJ, Clark B, Goetsch SJ, Hinson WH, Leavitt DD, Schlesinger DJ, Yenice KM. Anniversary Paper: the role of medical physicists in developing stereotactic radiosurgery. Med Phys. 2008 Sep; 35(9):4262-77. PMID: 18841876.
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    45. Keall PJ, Chang M, Benedict S, Thames H, Vedam SS, Lin PS. Investigating the temporal effects of respiratory-gated and intensity-modulated radiotherapy treatment delivery on in vitro survival: an experimental and theoretical study. Int J Radiat Oncol Biol Phys. 2008 Aug 01; 71(5):1547-52. PMID: 18495369.
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    46. Parker MS, Kelleher NM, Hoots JA, Chung JK, Fatouros PP, Benedict SH. Absorbed radiation dose of the female breast during diagnostic multidetector chest CT and dose reduction with a tungsten-antimony composite breast shield: preliminary results. Clin Radiol. 2008 Mar; 63(3):278-88. PMID: 18275868.
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    47. Cai J, Read PW, Baisden JM, Larner JM, Benedict SH, Sheng K. Estimation of error in maximal intensity projection-based internal target volume of lung tumors: a simulation and comparison study using dynamic magnetic resonance imaging. Int J Radiat Oncol Biol Phys. 2007 Nov 01; 69(3):895-902. PMID: 17889270.
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    48. Cai J, Sheng K, Sheehan JP, Benedict SH, Larner JM, Read PW. Evaluation of thoracic spinal cord motion using dynamic MRI. Radiother Oncol. 2007 Sep; 84(3):279-82. PMID: 17692979.
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    49. Baisden JM, Romney DA, Reish AG, Cai J, Sheng K, Jones DR, Benedict SH, Read PW, Larner JM. Dose as a function of lung volume and planned treatment volume in helical tomotherapy intensity-modulated radiation therapy-based stereotactic body radiation therapy for small lung tumors. Int J Radiat Oncol Biol Phys. 2007 Jul 15; 68(4):1229-37. PMID: 17513066.
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    50. Barani IJ, Cuttino LW, Benedict SH, Todor D, Bump EA, Wu Y, Chung TD, Broaddus WC, Lin PS. Neural stem cell-preserving external-beam radiotherapy of central nervous system malignancies. Int J Radiat Oncol Biol Phys. 2007 Jul 15; 68(4):978-85. PMID: 17467925.
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    51. Cai J, Miller GW, Altes TA, Read PW, Benedict SH, de Lange EE, Cates GD, Brookeman JR, Mugler JP, Sheng K. Direct measurement of lung motion using hyperpolarized helium-3 MR tagging. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):650-3. PMID: 17445997.
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    52. Barani IJ, Benedict SH, Lin PS. Neural stem cells: implications for the conventional radiotherapy of central nervous system malignancies. Int J Radiat Oncol Biol Phys. 2007 Jun 01; 68(2):324-33. PMID: 17398036.
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    53. Baisden JM, Benedict SH, Sheng K, Read PW, Larner JM. Helical TomoTherapy in the treatment of central nervous system metastasis. Neurosurg Focus. 2007 Mar 15; 22(3):E8. PMID: 17608361.
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    54. Song DY, Benedict SH, Cardinale RM, Chung TD, Chang MG, Schmidt-Ullrich RK. Stereotactic body radiation therapy of lung tumors: preliminary experience using normal tissue complication probability-based dose limits. Am J Clin Oncol. 2005 Dec; 28(6):591-6. PMID: 16317270.
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    55. Lightstone AW, Benedict SH, Bova FJ, Solberg TD, Stern RL. Intracranial stereotactic positioning systems: Report of the American Association of Physicists in Medicine Radiation Therapy Committee Task Group no. 68. Med Phys. 2005 Jul; 32(7):2380-98. PMID: 16121596.
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    56. Lightstone AW, Benedict SH, Bova FJ, Solberg TD, Stern RL. Intracranial stereotactic positioning systems: Report of the American Association of Physicists in Medicine Radiation Therapy Committee Task Group No. 68. Med Phys. 2005 Jul; 32(7Part1):2380-2398. PMID: 28493584.
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    57. Song DY, Kavanagh BD, Benedict SH, Schefter T. Stereotactic body radiation therapy. Rationale, techniques, applications, and optimization. Oncology (Williston Park). 2004 Oct; 18(11):1419-30; discussion 1430, 1432, 1435-6. PMID: 15609470.
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    58. Kavanagh BD, Timmerman RD, Benedict SH, Wu Q, Schefter TE, Stuhr K, McCourt S, Newman F, Cardinale RM, Gaspar LF. How should we describe the radioblologic effect of extracranial stereotactic radlosurgery: equivalent uniform dose or tumor control probability? Med Phys. 2003 Mar; 30(3):321-4. PMID: 12674231.
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    59. Eley KW, Benedict SH, Chung TD, Kavanagh BD, Broaddus WC, Schmidt-Ullrich RK, Lin PS. The effects of pentoxifylline on the survival of human glioma cells with continuous and intermittent stereotactic radiosurgery irradiation. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):542-50. PMID: 12243834.
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    60. Kavanagh BD, Schefter TE, Wu Q, Tong S, Newman F, Arnfield M, Benedict SH, McCourt S, Mohan R. Clinical application of intensity-modulated radiotherapy for locally advanced cervical cancer. Semin Radiat Oncol. 2002 Jul; 12(3):260-71. PMID: 12118391.
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    61. Schefter TE, Kavanagh BD, Wu Q, Tong S, Newman F, Mccourt S, Arnfield M, Benedict S, Mohan R. Technical considerations in the application of intensity-modulated radiotherapy as a concomitant integrated boost for locally-advanced cervix cancer. Med Dosim. 2002; 27(2):177-84. PMID: 12074470.
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    62. Kavanagh BD, Fischer BA, Segreti EM, Wheelock JB, Boardman C, Roseff SD, Cardinale RM, Benedict SH, Goram AL. Cost analysis of erythropoietin versus blood transfusions for cervical cancer patients receiving chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2001 Oct 01; 51(2):435-41. PMID: 11567818.
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    63. Benedict SH, Cardinale RM, Wu Q, Zwicker RD, Broaddus WC, Mohan R. Intensity-modulated stereotactic radiosurgery using dynamic micro-multileaf collimation. Int J Radiat Oncol Biol Phys. 2001 Jul 01; 50(3):751-8. PMID: 11395244.
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    64. Manning MA, Cardinale RM, Benedict SH, Kavanagh BD, Zwicker RD, Amir C, Broaddus WC. Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases. Int J Radiat Oncol Biol Phys. 2000 Jun 01; 47(3):603-8. PMID: 10837942.
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    65. Cardinale RM, Wu Q, Benedict SH, Kavanagh BD, Bump E, Mohan R. Determining the optimal block margin on the planning target volume for extracranial stereotactic radiotherapy. Int J Radiat Oncol Biol Phys. 1999 Sep 01; 45(2):515-20. PMID: 10487579.
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    66. Cardinale RM, Benedict SH, Wu Q, Zwicker RD, Gaballa HE, Mohan R. A comparison of three stereotactic radiotherapy techniques; ARCS vs. noncoplanar fixed fields vs. intensity modulation. Int J Radiat Oncol Biol Phys. 1998 Sep 01; 42(2):431-6. PMID: 9788426.
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    67. Cardinale RM, Schmidt-Ullrich RK, Benedict SH, Zwicker RD, Han DC, Broaddus WC. Accelerated radiotherapy regimen for malignant gliomas using stereotactic concomitant boosts for dose escalation. Radiat Oncol Investig. 1998; 6(4):175-81. PMID: 9727877.
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    68. Benedict SH, Lin PS, Zwicker RD, Huang DT, Schmidt-Ullrich RK. The biological effectiveness of intermittent irradiation as a function of overall treatment time: development of correction factors for linac-based stereotactic radiotherapy. Int J Radiat Oncol Biol Phys. 1997 Mar 01; 37(4):765-9. PMID: 9128949.
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    69. Kleck JH, Benedict SH, Cook JS, Birdsall RL, Satyamurthy N. Assessment of 18F gaseous releases during the production of 18F-fluorodeoxyglucose. Health Phys. 1991 May; 60(5):657-60. PMID: 2019496.
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    70. Cagnon CH, Benedict SH, Mankovich NJ, Bushberg JT, Seibert JA, Whiting JS. Exposure rates in high-level-control fluoroscopy for image enhancement. Radiology. 1991 Mar; 178(3):643-6. PMID: 1994395.
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    71. Weiss EL, Singer CM, Benedict SH, Baraff LJ. Physician exposure to ionizing radiation during trauma resuscitation: a prospective clinical study. Ann Emerg Med. 1990 Feb; 19(2):134-8. PMID: 2301790.
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    72. Makrigiorgos GM, Smathers JB, Myers LT, Benedict SH. Radiation quality investigations around a neutron therapy beam, using a high-pressure ionization chamber. Med Phys. 1990 Jan-Feb; 17(1):84-6. PMID: 2106613.
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    73. Singer CM, Baraff LJ, Benedict SH, Weiss EL, Singer BD. Exposure of emergency medicine personnel to ionizing radiation during cervical spine radiography. Ann Emerg Med. 1989 Aug; 18(8):822-5. PMID: 2757279.
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