Ruben C Fragoso

Title(s)Associate Professor, Radiation Oncology
SchoolSchool of Medicine
Address4501 X Street, Suite G140
CA 95817
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Promising response to vemurafenib and cobimetinib treatment for BRAF V600E mutated craniopharyngioma: a case report and literature review. CNS Oncol. 2024 Feb 13; CNS106. Yu N, Raslan OA, Lee HS, Theeler BJ, Raafat TA, Fragoso R, Shahlaie K, Aboud O. PMID: 38348829.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Application of Machine Learning to Metabolomic Profile Characterization in Glioblastoma Patients Undergoing Concurrent Chemoradiation. Metabolites. 2023 Feb 17; 13(2). Aboud O, Liu YA, Fiehn O, Brydges C, Fragoso R, Lee HS, Riess J, Hodeify R, Bloch O. PMID: 36837918; PMCID: PMC9961856.
      View in: PubMed   Mentions: 3  
    3. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511. Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    4. Orbital Rosai-Dorfman Disease Presenting as Optic Neuritis. J Neuroophthalmol. 2022 03 01; 42(1):e293-e296. Virk HS, Shahlaie K, Ramani B, Perry A, Fragoso R, Tuscano J, Liu YA. PMID: 35475853.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Effect and Safety of Radiation Therapy Boost to Extramesorectal Lymph Nodes in Rectal Cancer. Pract Radiat Oncol. 2020 Sep - Oct; 10(5):e372-e377. Chen H, Nguyen KNB, Huang H, Feng C, Zhao X, Daly ME, Rao S, Fragoso R, Valicenti R, Sekhon S, Navarro SM, Kim EJ, Cho M, Tam K, Farkas L, Halabi WJ, Monjazeb AM, Rong Y. PMID: 31866577.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 06; 24:101189. Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. PMID: 30986607; PMCID: PMC6463934.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    7. Outcomes of Preoperative Versus Postoperative Radiation for Heterotopic Ossification Prevention in Children With Neuromuscular Hip Dysplasia Undergoing Proximal Femoral Resection. J Pediatr Orthop. 2019 Feb; 39(2):e102-e107. Hess CB, Stein-Wexler R, Qi L, Davids JR, Fragoso RC. PMID: 29068805; PMCID: PMC5916744.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Glioblastoma Multiforme of the Conus Medullaris-Management Strategies and Complications. World Neurosurg. 2019 Apr; 124:101-109. Goodarzi A, Thaci B, Toussi A, Karnati T, Kim K, Fragoso R. PMID: 30639501.
      View in: PubMed   Mentions:    Fields:    
    9. Label-free fluorescence lifetime spectroscopy detects radiation-induced necrotic changes in live brain in real-time. Biomed Opt Express. 2018 Aug 01; 9(8):3559-3580. Hartl BA, Ma HSW, Sridharan S, Hansen KS, Kent MS, Gorin F, Fragoso RC, Marcu L. PMID: 30338140; PMCID: PMC6191615.
      View in: PubMed   Mentions: 4  
    10. Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site. Int J Radiat Oncol Biol Phys. 2018 08 01; 101(5):1259-1270. McGee HM, Daly ME, Azghadi S, Stewart SL, Oesterich L, Schlom J, Donahue R, Schoenfeld JD, Chen Q, Rao S, Fragoso RC, Valicenti RK, Canter RJ, Maverakis EM, Murphy WJ, Kelly K, Monjazeb AM. PMID: 29891204; PMCID: PMC6364565.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    11. Converting Treatment Plans From Helical Tomotherapy to L-Shape Linac: Clinical Workflow and Dosimetric Evaluation. Technol Cancer Res Treat. 2018 01 01; 17:1533033818785279. Yuan Z, Nair CK, Benedict SH, Valicenti RK, Rao S, Fragoso RC, Wright C, Qiu J, Rong Y. PMID: 29986638; PMCID: PMC6048611.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Patient-reported quality-of-life outcomes after de-escalated chemoradiation for human papillomavirus-positive oropharyngeal carcinoma: Findings from a phase 2 trial. Cancer. 2018 02 01; 124(3):521-529. Hegde JV, Shaverdian N, Daly ME, Felix C, Wong DL, Rosove MH, Garst JH, Wang PC, Veruttipong D, Rao S, Fragoso RC, Riess JW, Steinberg ML, Chen AM. PMID: 29044458; PMCID: PMC5916816.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    13. The effect of radiation dose on the onset and progression of radiation-induced brain necrosis in the rat model. Int J Radiat Biol. 2017 07; 93(7):676-682. Hartl BA, Ma HSW, Hansen KS, Perks J, Kent MS, Fragoso RC, Marcu L. PMID: 28306402; PMCID: PMC5751742.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsPHPublic Health
    14. NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype. J Immunol. 2015 Oct 15; 195(8):4010-9. Ames E, Canter RJ, Grossenbacher SK, Mac S, Chen M, Smith RC, Hagino T, Perez-Cunningham J, Sckisel GD, Urayama S, Monjazeb AM, Fragoso RC, Sayers TJ, Murphy WJ. PMID: 26363055; PMCID: PMC4781667.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    15. Intraoperative Extracorporeal Irradiation for the Treatment of the Meningioma-Infiltrated Calvarium. J Neurol Surg Rep. 2015 Jul; 76(1):e173-9. Kerr EE, Fragoso R, Schrot RJ, Shahlaie K. PMID: 26251799; PMCID: PMC4520997.
      View in: PubMed   Mentions:
    16. Improved clinical outcomes with multi-modality therapy for sinonasal undifferentiated carcinoma of the head and neck. Am J Otolaryngol. 2013 Nov-Dec; 34(6):658-63. Yoshida E, Aouad R, Fragoso R, Farwell DG, Gandour-Edwards R, Donald PJ, Chen AM. PMID: 23993024.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Fractionated stereotactic radiation therapy improves cranial neuropathies in patients with skull base meningiomas: a retrospective cohort study. Radiat Oncol. 2012 Dec 28; 7:225. Shen X, Andrews DW, Sergott RC, Evans JJ, Curran WJ, Machtay M, Fragoso R, Eldredge H, Champ CE, Witek M, Mishra MV, Dicker AP, Werner-Wasik M. PMID: 23270432; PMCID: PMC3551726.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies. Cancer Biol Ther. 2009 Nov; 8(22):2147-52. Donaldson JM, Kari C, Fragoso RC, Rodeck U, Williams JC. PMID: 19783899; PMCID: PMC3546534.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    19. A CD8/Lck transgene is able to drive thymocyte differentiation. J Immunol. 2006 Nov 01; 177(9):6007-17. Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ. PMID: 17056525.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    20. Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J Immunol. 2003 Jan 15; 170(2):913-21. Fragoso R, Ren D, Zhang X, Su MW, Burakoff SJ, Jin YJ. PMID: 12517957.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    21. CD8 T cells are sufficient to mediate allorecognition and allograft rejection. Cell Immunol. 2002 Mar-Apr; 216(1-2):6-14. Halamay KE, Kirkman RL, Sun L, Yamada A, Fragoso RC, Shimizu K, Mitchell RN, McKay DB. PMID: 12381345.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. J Immunol. 1996 Jun 15; 156(12):4535-8. Sen J, Kapeller R, Fragoso R, Sen R, Zon LI, Burakoff SJ. PMID: 8648093.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    23. Identification of upstream signals regulating interleukin-6 gene expression during in vitro treatment of human B cells with pokeweed mitogen. Blood. 1994 Oct 01; 84(7):2243-52. Chauhan D, Kharbanda S, Uchiyama H, Urashima M, Fragoso R, Sen J, Kufe DW, Anderson KC. PMID: 7919342.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
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