Oliver Fiehn

Title(s)Professor, Molecular and Cellular Biology
SchoolCollege of Biological Sciences
Address1315 GBSF (Genome Center)
CA 95616
Phone530-754-8258
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    Collapse Research 
    Collapse Research Activities and Funding
    Bruker timsTOF pro LC-MS system
    NIH S10OD030253Jun 15, 2021 - May 31, 2022
    Role: Principal Investigator
    West Coast Metabolomics Center for Compound Identification
    NIH U2CES030158Sep 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Novel Metabolic Predictors of Diabetes in American Indians
    NIH R01DK107532Sep 15, 2016 - Aug 31, 2021
    Role: Co-Principal Investigator
    2015 International Metabolomics Society Conference
    NIH R13DK105651Apr 1, 2015 - Mar 31, 2016
    Role: Principal Investigator
    West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)
    NIH U24DK097154Sep 4, 2012 - Aug 31, 2019
    Role: Principal Investigator
    Metabolomics: an accurate mass GC-DART AccuTOF mass spectrometer for routine iden
    NIH S10RR031630Sep 26, 2011 - Sep 25, 2012
    Role: Principal Investigator
    Environmental Impact on Perinatal Lung Metabolism
    NIH R01ES013932Sep 6, 2005 - May 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The BinDiscover database: a biology-focused meta-analysis tool for 156,000 GC-TOF MS metabolome samples. J Cheminform. 2023 Jul 20; 15(1):66. Bremer PL, Wohlgemuth G, Fiehn O. PMID: 37475020; PMCID: PMC10359220.
      View in: PubMed   Mentions: 1  
    2. IDSL.GOA: Gene Ontology Analysis for Metabolomics. bioRxiv. 2023 Jul 03. Mahajan P, Fiehn O, Barupal D. PMID: 37034715; PMCID: PMC10081191.
      View in: PubMed   Mentions:
    3. Alternative Identification of Glycosides Using MS/MS Matching with an In Silico-Modified Aglycone Mass Spectra Library. Anal Chem. 2023 07 18; 95(28):10618-10624. Rodríguez EP, Li Y, Vaniya A, Shih PM, Fiehn O. PMID: 37390485.
      View in: PubMed   Mentions:    Fields:    
    4. Longitudinal Lipidomic Profile of Hypertension in American Indians: Findings From the Strong Heart Family Study. Hypertension. 2023 08; 80(8):1771-1783. Chen M, Miao G, Zhang Y, Umans JG, Lee ET, Howard BV, Fiehn O, Zhao J. PMID: 37334699.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Dietary Docosahexaenoic Acid and Glucose Systemic Metabolic Changes in the Mouse. Nutrients. 2023 Jun 08; 15(12). Watkins BA, Newman JW, Kuchel GA, Fiehn O, Kim J. PMID: 37375583; PMCID: PMC10303726.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Human metabolome variation along the upper intestinal tract. Nat Metab. 2023 05; 5(5):777-788. Folz J, Culver RN, Morales JM, Grembi J, Triadafilopoulos G, Relman DA, Huang KC, Shalon D, Fiehn O. PMID: 37165176; PMCID: PMC10229427.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Profiling the human intestinal environment under physiological conditions. Nature. 2023 May; 617(7961):581-591. Shalon D, Culver RN, Grembi JA, Folz J, Treit PV, Shi H, Rosenberger FA, Dethlefsen L, Meng X, Yaffe E, Aranda-Díaz A, Geyer PE, Mueller-Reif JB, Spencer S, Patterson AD, Triadafilopoulos G, Holmes SP, Mann M, Fiehn O, Relman DA, Huang KC. PMID: 37165188; PMCID: PMC10191855.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    8. Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo. Proc Natl Acad Sci U S A. 2023 05 16; 120(20):e2220334120. Fong LY, Huebner K, Jing R, Smalley KJ, Brydges CR, Fiehn O, Farber JL, Croce CM. PMID: 37155893; PMCID: PMC10193985.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Short-Term Stability of Serum and Liver Extracts for Untargeted Metabolomics and Lipidomics. Antioxidants (Basel). 2023 Apr 24; 12(5). Hricko J, Rudl Kulhava L, Paucova M, Novakova M, Kuda O, Fiehn O, Cajka T. PMID: 37237852; PMCID: PMC10215277.
      View in: PubMed   Mentions:
    10. Longitudinal lipidomic signatures of all-cause and CVD mortality in American Indians: findings from the Strong Heart Study. Geroscience. 2023 Apr 13. Miao G, Fiehn O, Malloy KM, Zhang Y, Lee ET, Howard BV, Zhao J. PMID: 37055600.
      View in: PubMed   Mentions:    Fields:    
    11. Metabolomic analysis of maternal mid-gestation plasma and cord blood in autism spectrum disorders. Mol Psychiatry. 2023 Apr 10. Che X, Roy A, Bresnahan M, Mjaaland S, Reichborn-Kjennerud T, Magnus P, Stoltenberg C, Shang Y, Zhang K, Susser E, Fiehn O, Lipkin WI. PMID: 37037873.
      View in: PubMed   Mentions:    Fields:    
    12. Effect of pentobarbital as a euthanasia agent on equine in vitro embryo production. Theriogenology. 2023 Jul 15; 205:1-8. Martin-Pelaez S, Rabow Z, de la Fuente A, Draheim P, Loynachan A, Fiehn O, Meyers S, Lyman C, Dini P. PMID: 37084499.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population. Front Nutr. 2023; 10:1040993. Buckner T, Johnson RK, Vanderlinden LA, Carry PM, Romero A, Onengut-Gumuscu S, Chen WM, Kim S, Fiehn O, Frohnert BI, Crume T, Perng W, Kechris K, Rewers M, Norris JM. PMID: 37057071; PMCID: PMC10086335.
      View in: PubMed   Mentions:
    14. A pilot study on metabolomic characterization of human glioblastomas and patient plasma. Res Sq. 2023 Mar 10. Liu A, Aboud O, Dahabiyeh LA, Bloch O, Fiehn O. PMID: 36945517; PMCID: PMC10029122.
      View in: PubMed   Mentions:
    15. The artificial sweetener erythritol and cardiovascular event risk. Nat Med. 2023 03; 29(3):710-718. Witkowski M, Nemet I, Alamri H, Wilcox J, Gupta N, Nimer N, Haghikia A, Li XS, Wu Y, Saha PP, Demuth I, König M, Steinhagen-Thiessen E, Cajka T, Fiehn O, Landmesser U, Tang WHW, Hazen SL. PMID: 36849732; PMCID: PMC10334259.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    16. Application of Machine Learning to Metabolomic Profile Characterization in Glioblastoma Patients Undergoing Concurrent Chemoradiation. Metabolites. 2023 Feb 17; 13(2). Aboud O, Liu YA, Fiehn O, Brydges C, Fragoso R, Lee HS, Riess J, Hodeify R, Bloch O. PMID: 36837918; PMCID: PMC9961856.
      View in: PubMed   Mentions: 1  
    17. An Oxylipin-Related Nutrient Pattern and Risk of Type 1 Diabetes in the Diabetes Autoimmunity Study in the Young (DAISY). Nutrients. 2023 Feb 14; 15(4). Buckner T, Johnson RK, Vanderlinden LA, Carry PM, Romero A, Onengut-Gumuscu S, Chen WM, Fiehn O, Frohnert BI, Crume T, Perng W, Kechris K, Rewers M, Norris JM. PMID: 36839302; PMCID: PMC9962656.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. In utero metabolomic signatures of refined grain intake and risk of gestational diabetes: A metabolome-wide association study. Am J Clin Nutr. 2023 04; 117(4):731-740. Chehab RF, Ferrara A, Zheng S, Barupal DK, Ngo AL, Chen L, Fiehn O, Zhu Y. PMID: 36781127; PMCID: PMC10273195.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Cellular transformation promotes the incorporation of docosahexaenoic acid into the endolysosome-specific lipid bis(monoacylglycerol)phosphate in breast cancer. Cancer Lett. 2023 03 31; 557:216090. Berg AL, Showalter MR, Kosaisawe N, Hu M, Stephens NC, Sa M, Heil H, Castro N, Chen JJ, VanderVorst K, Wheeler MR, Rabow Z, Cajka T, Albeck J, Fiehn O, Carraway KL. PMID: 36773796.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    20. The unknown lipids project: harmonized methods improve compound identification and data reproducibility in an inter-laboratory untargeted lipidomics study. bioRxiv. 2023 Feb 03. Shen T, Conway C, Rempfert KR, Kyle JE, Colby SM, Gaul DA, Habra H, Kong F, Bloodsworth KJ, Allen D, Evans BS, Du X, Fernandez FM, Metz TO, Fiehn O, Evans CR. PMID: 36778509; PMCID: PMC9915661.
      View in: PubMed   Mentions:
    21. Alteration of glycosphingolipid metabolism by ozone is associated with exacerbation of allergic asthma characteristics in mice. Toxicol Sci. 2023 01 31; 191(1):79-89. Stevens NC, Brown VJ, Domanico MC, Edwards PC, Van Winkle LS, Fiehn O. PMID: 36331340; PMCID: PMC9887677.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    22. Plasma lipidomic profile of depressive symptoms: a longitudinal study in a large sample of community-dwelling American Indians in the strong heart study. Mol Psychiatry. 2023 Jan 19. Miao G, Deen J, Struzeski JB, Chen M, Zhang Y, Cole SA, Fretts AM, Lee ET, Howard BV, Fiehn O, Zhao J. PMID: 36653676.
      View in: PubMed   Mentions: 2     Fields:    
    23. Comprehensive lipidomic profiling by plasma separation cards. Anal Bioanal Chem. 2022 Nov 01. Bishop LM, Fiehn O. PMID: 36316462.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication. JVS Vasc Sci. 2022; 3:379-388. Bellomo TR, Tsao NL, Johnston-Cox H, Borkowski K, Shakt G, Judy R, Moore J, Ractcliffe SJ, Fiehn O, Floyd TF, Wehrli FW, Mohler E, Newman JW, Damrauer SM. PMID: 36568282; PMCID: PMC9772856.
      View in: PubMed   Mentions:
    25. Metabolome-Wide Associations of Gestational Weight Gain in Pregnant Women with Overweight and Obesity. Metabolites. 2022 Oct 11; 12(10). Dai J, Boghossian NS, Sarzynski MA, Luo F, Sun X, Li J, Fiehn O, Liu J, Chen L. PMID: 36295862; PMCID: PMC9609233.
      View in: PubMed   Mentions:
    26. Beyond the Ground State: Predicting Electron Ionization Mass Spectra Using Excited-State Molecular Dynamics. J Chem Inf Model. 2022 09 26; 62(18):4403-4410. Wang S, Kind T, Bremer PL, Tantillo DJ, Fiehn O. PMID: 36107950.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    27. How Well Can We Predict Mass Spectra from Structures? Benchmarking Competitive Fragmentation Modeling for Metabolite Identification on Untrained Tandem Mass Spectra. J Chem Inf Model. 2022 09 12; 62(17):4049-4056. Bremer PL, Vaniya A, Kind T, Wang S, Fiehn O. PMID: 36043939.
      View in: PubMed   Mentions: 1     Fields:    
    28. Blood Levels of Endocannabinoids, Oxylipins, and Metabolites Are Altered in Hemodialysis Patients. Int J Mol Sci. 2022 Aug 29; 23(17). Watkins BA, Friedman AN, Kim J, Borkowski K, Kaiser S, Fiehn O, Newman JW. PMID: 36077177; PMCID: PMC9456435.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1. Cells. 2022 08 13; 11(16). Rabow Z, Laubach K, Kong X, Shen T, Mohibi S, Zhang J, Fiehn O, Chen X. PMID: 36010592; PMCID: PMC9406568.
      View in: PubMed   Mentions: 1     Fields:    
    30. Lipidomics profiling of biological aging in American Indians: the Strong Heart Family Study. Geroscience. 2023 02; 45(1):359-369. Subedi P, Palma-Gudiel H, Fiehn O, Best LG, Lee ET, Howard BV, Zhao J. PMID: 35953607; PMCID: PMC9886745.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Fluoroacetate distribution, response to fluoridation, and synthesis in juvenile Gastrolobium bilobum plants. Phytochemistry. 2022 Oct; 202:113356. Leong BJ, Folz JS, Bathe U, Clark DG, Fiehn O, Hanson AD. PMID: 35934105.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    32. Predictive Metabolomic Markers in Early to Mid-pregnancy for Gestational Diabetes Mellitus: A Prospective Test and Validation Study. Diabetes. 2022 08 01; 71(8):1807-1817. Zhu Y, Barupal DK, Ngo AL, Quesenberry CP, Feng J, Fiehn O, Ferrara A. PMID: 35532743; PMCID: PMC9490360.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety-A Role for Bile Acids. Front Neurosci. 2022; 16:937906. MahmoudianDehkordi S, Bhattacharyya S, Brydges CR, Jia W, Fiehn O, Rush AJ, Dunlop BW, Kaddurah-Daouk R. PMID: 35937867; PMCID: PMC9350527.
      View in: PubMed   Mentions: 7  
    34. Metabolomic Evidence for Peroxisomal Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Int J Mol Sci. 2022 Jul 18; 23(14). Che X, Brydges CR, Yu Y, Price A, Joshi S, Roy A, Lee B, Barupal DK, Cheng A, Palmer DM, Levine S, Peterson DL, Vernon SD, Bateman L, Hornig M, Montoya JG, Komaroff AL, Fiehn O, Lipkin WI. PMID: 35887252; PMCID: PMC9320121.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Lipidomic profiling in the Strong Heart Study identified American Indians at risk of chronic kidney disease. Kidney Int. 2022 11; 102(5):1154-1166. Zeng W, Beyene HB, Kuokkanen M, Miao G, Magliano DJ, Umans JG, Franceschini N, Cole SA, Michailidis G, Lee ET, Howard BV, Fiehn O, Curran JE, Blangero J, Meikle PJ, Zhao J. PMID: 35853479.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    36. Metabolite Damage and Damage Control in a Minimal Genome. mBio. 2022 08 30; 13(4):e0163022. Haas D, Thamm AM, Sun J, Huang L, Sun L, Beaudoin GAW, Wise KS, Lerma-Ortiz C, Bruner SD, Breuer M, Luthey-Schulten Z, Lin J, Wilson MA, Brown G, Yakunin AF, Kurilyak I, Folz J, Fiehn O, Glass JI, Hanson AD, Henry CS, de Crécy-Lagard V. PMID: 35862786; PMCID: PMC9426524.
      View in: PubMed   Mentions: 4     Fields:    
    37. An adaptive teosinte mexicana introgression modulates phosphatidylcholine levels and is associated with maize flowering time. Proc Natl Acad Sci U S A. 2022 07 05; 119(27):e2100036119. Barnes AC, Rodríguez-Zapata F, Juárez-Núñez KA, Gates DJ, Janzen GM, Kur A, Wang L, Jensen SE, Estévez-Palmas JM, Crow TM, Kavi HS, Pil HD, Stokes RL, Knizner KT, Aguilar-Rangel MR, Demesa-Arévalo E, Skopelitis T, Pérez-Limón S, Stutts WL, Thompson P, Chiu YC, Jackson D, Muddiman DC, Fiehn O, Runcie D, Buckler ES, Ross-Ibarra J, Hufford MB, Sawers RJH, Rellán-Álvarez R. PMID: 35771940; PMCID: PMC9271162.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    38. Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures. iScience. 2022 Jul 15; 25(7):104602. Soták M, Rajan MR, Clark M, Harms M, Rani A, Kraft JD, Tandio D, Shen T, Borkowski K, Fiehn O, Newman JW, Quiding-Järbrink M, Biörserud C, Apelgren P, Staalesen T, Hagberg CE, Boucher J, Wallenius V, Lange S, Börgeson E. PMID: 35789845; PMCID: PMC9249816.
      View in: PubMed   Mentions: 2  
    39. Correction to "Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast Cancer─Link to Patient Survival, Hormone Receptor Status, and Metabolic Profiling". J Proteome Res. 2022 Jul 01; 21(7):1787. Brockmöller SF, Bucher E, Müller BM, Budczies J, Hilvo M, Griffin JL, Orešic M, Kallioniemi O, Iljin K, Loibl S, Darb-Esfahani S, Sinn BV, Klauschen F, Prinzler J, Bangemann N, Ismaeel F, Fiehn O, Dietel M, Denkert C. PMID: 35642679.
      View in: PubMed   Mentions:    Fields:    
    40. Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD. Int J Mol Sci. 2022 May 27; 23(11). Mandala A, Dobrinskikh E, Janssen RC, Fiehn O, D'Alessandro A, Friedman JE, Jonscher KR. PMID: 35682720; PMCID: PMC9181499.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    41. Arachidonic acid metabolism and inflammatory biomarkers associated with exposure to polycyclic aromatic hydrocarbons. Environ Res. 2022 09; 212(Pt D):113498. Lin Y, Lu X, Qiu X, Yin F, Faull KF, Tseng CH, Zhang JJ, Fiehn O, Zhu T, Araujo JA, Zhu Y. PMID: 35613629.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    42. Polyamine Metabolites as Biomarkers in Head and Neck Cancer Biofluids. Diagnostics (Basel). 2022 Mar 24; 12(4). DeFelice BC, Fiehn O, Belafsky P, Ditterich C, Moore M, Abouyared M, Beliveau AM, Farwell DG, Bewley AF, Clayton SM, Archard JA, Pavlic J, Rao S, Kuhn M, Deng P, Halmai J, Fink KD, Birkeland AC, Anderson JD. PMID: 35453845; PMCID: PMC9024570.
      View in: PubMed   Mentions: 4  
    43. Almond Consumption for 8 Weeks Altered Host and Microbial Metabolism in Comparison to a Control Snack in Young Adults. J Am Nutr Assoc. 2023 Mar-Apr; 42(3):242-254. Dhillon J, Newman JW, Fiehn O, Ortiz RM. PMID: 35512761; PMCID: PMC9396742.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    44. Plasma Oxylipin Profile Discriminates Ethnicities in Subjects with Non-Alcoholic Steatohepatitis: An Exploratory Analysis. Metabolites. 2022 Feb 19; 12(2). Mazi TA, Borkowski K, Fiehn O, Bowlus CL, Sarkar S, Matsukuma K, Ali MR, Kieffer DA, Wan YY, Stanhope KL, Havel PJ, Newman JW, Medici V. PMID: 35208265; PMCID: PMC8875408.
      View in: PubMed   Mentions:
    45. Triglyceride profiles are associated with subacute exposure to bisphenol A in healthy young adults. Sci Total Environ. 2022 Jun 15; 825:153991. Lu X, Lin Y, Qiu X, Liu J, Zhu T, Araujo JA, Fiehn O, Zhu Y. PMID: 35192814.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Metabolomic and inflammatory signatures of symptom dimensions in major depression. Brain Behav Immun. 2022 05; 102:42-52. Brydges CR, Bhattacharyya S, Dehkordi SM, Milaneschi Y, Penninx B, Jansen R, Kristal BS, Han X, Arnold M, Kastenmüller G, Bekhbat M, Mayberg HS, Craighead WE, Rush AJ, Fiehn O, Dunlop BW, Kaddurah-Daouk R, Mood Disorders Precision Medicine Consortium. PMID: 35131442; PMCID: PMC9241382.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Acyl-CoA Identification in Mouse Liver Samples Using the In Silico CoA-Blast Tandem Mass Spectral Library. Anal Chem. 2022 02 15; 94(6):2732-2739. Keshet U, Kind T, Lu X, Devi S, Fiehn O. PMID: 35119811.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    48. Evaluating the Accuracy of the QCEIMS Approach for Computational Prediction of Electron Ionization Mass Spectra of Purines and Pyrimidines. Metabolites. 2022 Jan 12; 12(1). Lee J, Kind T, Tantillo DJ, Wang LP, Fiehn O. PMID: 35050190; PMCID: PMC8779335.
      View in: PubMed   Mentions: 1  
    49. Evidence for Peroxisomal Dysfunction and Dysregulation of the CDP-Choline Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. medRxiv. 2022 Jan 11. Che X, Brydges CR, Yu Y, Price A, Joshi S, Roy A, Lee B, Barupal DK, Cheng A, Palmer DM, Levine S, Peterson DL, Vernon SD, Bateman L, Hornig M, Montoya JG, Komaroff AL, Fiehn O, Lipkin WI. PMID: 35043127; PMCID: PMC8764736.
      View in: PubMed   Mentions:
    50. Quantum Chemical Prediction of Electron Ionization Mass Spectra of Trimethylsilylated Metabolites. Anal Chem. 2022 01 25; 94(3):1559-1566. Wang S, Kind T, Bremer PL, Tantillo DJ, Fiehn O. PMID: 35006668.
      View in: PubMed   Mentions: 1     Fields:    
    51. Host lipidome and tuberculosis treatment failure. Eur Respir J. 2022 01; 59(1). Shivakoti R, Newman JW, Hanna LE, Queiroz ATL, Borkowski K, Gupte AN, Paradkar M, Satyamurthi P, Kulkarni V, Selva M, Pradhan N, Shivakumar SVBY, Natarajan S, Karunaianantham R, Gupte N, Thiruvengadam K, Fiehn O, Bharadwaj R, Kagal A, Gaikwad S, Sangle S, Golub JE, Andrade BB, Mave V, Gupta A, Padmapriyadarsini C. PMID: 34375300; PMCID: PMC9625841.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    52. Untargeted Metabolomics Analysis of the Serum Metabolic Signature of Childhood Obesity. Nutrients. 2022 Jan 04; 14(1). Szczerbinski L, Wojciechowska G, Olichwier A, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Goscik J, Fiehn O, Fan S, Wasilewska A, Taranta-Janusz K, Kretowski A. PMID: 35011090; PMCID: PMC8747180.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    53. CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop. Mol Metab. 2022 02; 56:101426. Chen Y, Capello M, Rios Perez MV, Vykoukal JV, Roife D, Kang Y, Prakash LR, Katayama H, Irajizad E, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Do KA, Fiehn O, Maitra A, Wang H, Chiao PJ, Katz MHG, Fleming JB, Hanash SM, Fahrmann JF. PMID: 34971802; PMCID: PMC8841288.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    54. Chemical-damage MINE: A database of curated and predicted spontaneous metabolic reactions. Metab Eng. 2022 01; 69:302-312. Jeffryes JG, Lerma-Ortiz C, Liu F, Golubev A, Niehaus TD, Elbadawi-Sidhu M, Fiehn O, Hanson AD, Tyo KE, Henry CS. PMID: 34958914.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    55. Spectral entropy outperforms MS/MS dot product similarity for small-molecule compound identification. Nat Methods. 2021 12; 18(12):1524-1531. Li Y, Kind T, Folz J, Vaniya A, Mehta SS, Fiehn O. PMID: 34857935.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    56. Chemical set enrichment analysis: Novel insights into sex-specific alterations in primary metabolites in posttraumatic stress and disturbed sleep. Clin Transl Med. 2021 12; 11(12):e511. Bhargava A, Fan S, Lujan CR, Fiehn O, Neylan TC, Inslicht SS. PMID: 34936734; PMCID: PMC8694503.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    57. Metabolomics of Lung Microdissections Reveals Region- and Sex-Specific Metabolic Effects of Acute Naphthalene Exposure in Mice. Toxicol Sci. 2021 11 24; 184(2):214-222. Stevens NC, Edwards PC, Tran LM, Ding X, Van Winkle LS, Fiehn O. PMID: 34498071; PMCID: PMC8633889.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    58. Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis. Dig Dis Sci. 2022 08; 67(8):3831-3841. Dong TS, Jacobs JP, Agopian V, Pisegna JR, Ayoub W, Durazo F, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Lagishetty V, Fiehn O, Goodman MT, Elashoff D, Hussain SK. PMID: 34799768; PMCID: PMC9287237.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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    233. Eighteen new oleaginous yeast species. J Ind Microbiol Biotechnol. 2016 07; 43(7):887-900. Garay LA, Sitepu IR, Cajka T, Chandra I, Shi S, Lin T, German JB, Fiehn O, Boundy-Mills KL. PMID: 27072563.
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    234. Metabolomics by Gas Chromatography-Mass Spectrometry: Combined Targeted and Untargeted Profiling. Curr Protoc Mol Biol. 2016 Apr 01; 114:30.4.1-30.4.32. Fiehn O. PMID: 27038389; PMCID: PMC4829120.
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    235. Evidence that COG0325 proteins are involved in PLP homeostasis. Microbiology (Reading). 2016 Apr; 162(4):694-706. Prunetti L, El Yacoubi B, Schiavon CR, Kirkpatrick E, Huang L, Bailly M, El Badawi-Sidhu M, Harrison K, Gregory JF, Fiehn O, Hanson AD, de Crécy-Lagard V. PMID: 26872910.
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    236. Evaluation of metabolomics profiles of grain from maize hybrids derived from near-isogenic GM positive and negative segregant inbreds demonstrates that observed differences cannot be attributed unequivocally to the GM trait. Metabolomics. 2016; 12:82. Harrigan GG, Venkatesh TV, Leibman M, Blankenship J, Perez T, Halls S, Chassy AW, Fiehn O, Xu Y, Goodacre R. PMID: 27453709; PMCID: PMC4940444.
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    237. Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer. Cancer Biomark. 2016 Mar 11; 16(4):609-17. Fahrmann JF, Grapov D, DeFelice BC, Taylor S, Kim K, Kelly K, Wikoff WR, Pass H, Rom WN, Fiehn O, Miyamoto S. PMID: 27002763.
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    238. Metabolomic Assessment of Key Maize Resources: GC-MS and NMR Profiling of Grain from B73 Hybrids of the Nested Association Mapping (NAM) Founders and of Geographically Diverse Landraces. J Agric Food Chem. 2016 Mar 16; 64(10):2162-72. Venkatesh TV, Chassy AW, Fiehn O, Flint-Garcia S, Zeng Q, Skogerson K, Harrigan GG. PMID: 26923484.
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    239. Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Elife. 2016 Feb 26; 5. Fiehn O, Showalter MR, Schaner-Tooley CE, Reproducibility Project: Cancer Biology, Reproducibility Project Cancer Biology. PMID: 26943899; PMCID: PMC4786416.
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    240. Ultrafast Polyphenol Metabolomics of Red Wines Using MicroLC-MS/MS. J Agric Food Chem. 2016 Jan 20; 64(2):505-12. Ma Y, Tanaka N, Vaniya A, Kind T, Fiehn O. PMID: 26698107; PMCID: PMC8168920.
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    241. Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics. Anal Chem. 2016 Jan 05; 88(1):524-45. Cajka T, Fiehn O. PMID: 26637011.
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    242. Metabolite Damage and Metabolite Damage Control in Plants. Annu Rev Plant Biol. 2016 04 29; 67:131-52. Hanson AD, Henry CS, Fiehn O, de Crécy-Lagard V. PMID: 26667673.
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    243. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nat Cell Biol. 2015 Dec; 17(12):1523-35. Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. PMID: 26571212; PMCID: PMC4662931.
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    246. Lipidomic Analysis of Chlamydomonas reinhardtii under Nitrogen and Sulfur Deprivation. PLoS One. 2015; 10(9):e0137948. Yang D, Song D, Kind T, Ma Y, Hoefkens J, Fiehn O. PMID: 26375463; PMCID: PMC4574153.
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    247. Integrating Multiple Analytical Datasets to Compare Metabolite Profiles of Mouse Colonic-Cecal Contents and Feces. Metabolites. 2015 Sep 11; 5(3):489-501. Zeng H, Grapov D, Jackson MI, Fahrmann J, Fiehn O, Combs GF. PMID: 26378591; PMCID: PMC4588808.
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    249. Investigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1716-23. Fahrmann JF, Kim K, DeFelice BC, Taylor SL, Gandara DR, Yoneda KY, Cooke DT, Fiehn O, Kelly K, Miyamoto S. PMID: 26282632; PMCID: PMC4633344.
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    250. Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B. J Clin Oncol. 2015 Nov 20; 33(33):3880-6. Wikoff WR, Hanash S, DeFelice B, Miyamoto S, Barnett M, Zhao Y, Goodman G, Feng Z, Gandara D, Fiehn O, Taguchi A. PMID: 26282655; PMCID: PMC4652011.
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    251. Retention projection enables accurate calculation of liquid chromatographic retention times across labs and methods. J Chromatogr A. 2015 Sep 18; 1412:43-51. Abate-Pella D, Freund DM, Ma Y, Simón-Manso Y, Hollender J, Broeckling CD, Huhman DV, Krokhin OV, Stoll DR, Hegeman AD, Kind T, Fiehn O, Schymanski EL, Prenni JE, Sumner LW, Boswell PG. PMID: 26292625; PMCID: PMC4556278.
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    252. Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass. Cell Rep. 2015 Jul 21; 12(3):495-510. Solloway MJ, Madjidi A, Gu C, Eastham-Anderson J, Clarke HJ, Kljavin N, Zavala-Solorio J, Kates L, Friedman B, Brauer M, Wang J, Fiehn O, Kolumam G, Stern H, Lowe JB, Peterson AS, Allan BB. PMID: 26166562.
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    253. Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study. Am J Clin Nutr. 2015 Aug; 102(2):433-43. Liesenfeld DB, Grapov D, Fahrmann JF, Salou M, Scherer D, Toth R, Habermann N, Böhm J, Schrotz-King P, Gigic B, Schneider M, Ulrich A, Herpel E, Schirmacher P, Fiehn O, Lampe JW, Ulrich CM. PMID: 26156741; PMCID: PMC4515859.
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    255. Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures. Metabolomics. 2015 Jun 01; 11(3):707-721. Meissen JK, Hirahatake KM, Adams SH, Fiehn O. PMID: 26190955; PMCID: PMC4504739.
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    256. Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. BMC Genomics. 2015 May 15; 16:382. Niehaus TD, Gerdes S, Hodge-Hanson K, Zhukov A, Cooper AJ, ElBadawi-Sidhu M, Fiehn O, Downs DM, Hanson AD. PMID: 25975565; PMCID: PMC4433059.
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    257. Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung-targeted approach to deliver statins. Physiol Rep. 2015 May 11; 3(5). Zeki AA, Bratt JM, Chang KY, Franzi LM, Ott S, Silveria M, Fiehn O, Last JA, Kenyon NJ. PMID: 25969462; PMCID: PMC4463814.
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    258. MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis. Nat Methods. 2015 Jun; 12(6):523-6. Tsugawa H, Cajka T, Kind T, Ma Y, Higgins B, Ikeda K, Kanazawa M, VanderGheynst J, Fiehn O, Arita M. PMID: 25938372; PMCID: PMC4449330.
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    259. Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry. Metabolites. 2015 Apr 09; 5(2):192-210. Miyamoto S, Taylor SL, Barupal DK, Taguchi A, Wohlgemuth G, Wikoff WR, Yoneda KY, Gandara DR, Hanash SM, Kim K, Fiehn O. PMID: 25859693; PMCID: PMC4495369.
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    261. MetaMapR: pathway independent metabolomic network analysis incorporating unknowns. Bioinformatics. 2015 Aug 15; 31(16):2757-60. Grapov D, Wanichthanarak K, Fiehn O. PMID: 25847005; PMCID: PMC4528626.
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    262. Diabetes Associated Metabolomic Perturbations in NOD Mice. Metabolomics. 2015 Apr; 11(2):425-437. Grapov D, Fahrmann J, Hwang J, Poudel A, Jo J, Periwal V, Fiehn O, Hara M. PMID: 25755629; PMCID: PMC4351755.
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    263. Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis. J Ren Nutr. 2015 Jul; 25(4):351-6. Kaysen GA, Johansen KL, Chertow GM, Dalrymple LS, Kornak J, Grimes B, Dwyer T, Chassy AW, Fiehn O. PMID: 25802017; PMCID: PMC4469547.
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    264. Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network. Plant Physiol. 2015 Apr; 167(4):1685-98. Kim T, Dreher K, Nilo-Poyanco R, Lee I, Fiehn O, Lange BM, Nikolau BJ, Sumner L, Welti R, Wurtele ES, Rhee SY. PMID: 25670818; PMCID: PMC4378150.
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    265. Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma. Cancer Prev Res (Phila). 2015 May; 8(5):410-8. Wikoff WR, Grapov D, Fahrmann JF, DeFelice B, Rom WN, Pass HI, Kim K, Nguyen U, Taylor SL, Gandara DR, Kelly K, Fiehn O, Miyamoto S. PMID: 25657018; PMCID: PMC4618700.
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    266. Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial. J Nutr. 2015 Apr; 145(4):691-700. Piccolo BD, Comerford KB, Karakas SE, Knotts TA, Fiehn O, Adams SH. PMID: 25833773.
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    267. Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction. J Nutr. 2015 Apr; 145(4):681-90. Piccolo BD, Keim NL, Fiehn O, Adams SH, Van Loan MD, Newman JW. PMID: 25833772; PMCID: PMC4381764.
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    268. Efficiency of short, small-diameter columns for reversed-phase liquid chromatography under practical operating conditions. J Chromatogr A. 2015 Feb 27; 1383:47-57. Ma Y, Chassy AW, Miyazaki S, Motokawa M, Morisato K, Uzu H, Ohira M, Furuno M, Nakanishi K, Minakuchi H, Mriziq K, Farkas T, Fiehn O, Tanaka N. PMID: 25648581.
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    269. Introducing the USA Plant, Algae and Microbial Metabolomics Research Coordination Network (PAMM-NET). Metabolomics. 2015 Feb; 11(1):3-5. Sumner LW, Styczynski M, McLean J, Fiehn O, Jander G, Liao J, Sumner S, Britz-McKibbin P, Welti R, Jones AD, Dorrestein PC, Bearden D, Kaddurah-Daouk R. PMID: 28018159; PMCID: PMC5178969.
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    270. Cardiac steatosis potentiates angiotensin II effects in the heart. Am J Physiol Heart Circ Physiol. 2015 Feb 15; 308(4):H339-50. Glenn DJ, Cardema MC, Ni W, Zhang Y, Yeghiazarians Y, Grapov D, Fiehn O, Gardner DG. PMID: 25485904; PMCID: PMC4329483.
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    271. High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy. Circ Cardiovasc Genet. 2014 Dec; 7(6):955-964. Snowden SG, Grapov D, Settergren M, D'Alexandri FL, Haeggström JZ, Fiehn O, Hyötyläinen T, Pedersen TL, Newman JW, Orešic M, Pernow J, Wheelock CE. PMID: 25516625; PMCID: PMC4270085.
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    272. Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics. Pharmacogenomics. 2014 Dec; 15(16):1947-62. Tay-Sontheimer J, Shireman LM, Beyer RP, Senn T, Witten D, Pearce RE, Gaedigk A, Gana Fomban CL, Lutz JD, Isoherranen N, Thummel KE, Fiehn O, Leeder JS, Lin YS. PMID: 25521354; PMCID: PMC4486214.
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    273. The use of metabolomics in population-based research. Adv Nutr. 2014 Nov; 5(6):785-8. Su LJ, Fiehn O, Maruvada P, Moore SC, O'Keefe SJ, Wishart DS, Zanetti KA. PMID: 25398741; PMCID: PMC4224215.
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    274. LipidBlast templates as flexible tools for creating new in-silico tandem mass spectral libraries. Anal Chem. 2014 Nov 18; 86(22):11024-7. Kind T, Okazaki Y, Saito K, Fiehn O. PMID: 25340521; PMCID: PMC4238643.
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    275. Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. F1000Res. 2014; 3:248. Armstrong AW, Wu J, Johnson MA, Grapov D, Azizi B, Dhillon J, Fiehn O. PMID: 25580230; PMCID: PMC4288418.
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    276. Plant-driven repurposing of the ancient S-adenosylmethionine repair enzyme homocysteine S-methyltransferase. Biochem J. 2014 Oct 15; 463(2):279-86. Bradbury LM, Ziemak MJ, El Badawi-Sidhu M, Fiehn O, Hanson AD. PMID: 25046177.
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    277. MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra. Anal Chem. 2014 Nov 04; 86(21):10724-31. Ma Y, Kind T, Yang D, Leon C, Fiehn O. PMID: 25263576; PMCID: PMC4222628.
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    278. Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry. Trends Analyt Chem. 2014 Oct 01; 61:192-206. Cajka T, Fiehn O. PMID: 25309011; PMCID: PMC4187118.
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    279. Metabolomics insights into pathophysiological mechanisms of interstitial cystitis. Int Neurourol J. 2014 Sep; 18(3):106-14. Fiehn O, Kim J. PMID: 25279237; PMCID: PMC4180160.
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    280. Glutamate enrichment as new diagnostic opportunity in breast cancer. Int J Cancer. 2015 Apr 01; 136(7):1619-28. Budczies J, Pfitzner BM, Györffy B, Winzer KJ, Radke C, Dietel M, Fiehn O, Denkert C. PMID: 25155347.
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    281. Comparative evaluation of extraction methods for simultaneous mass-spectrometric analysis of complex lipids and primary metabolites from human blood plasma. Anal Bioanal Chem. 2014 Nov; 406(28):7275-86. Lee DY, Kind T, Yoon YR, Fiehn O, Liu KH. PMID: 25171832.
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    282. Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids. Plant Cell. 2014 Jul; 26(7):3010-22. Niehaus TD, Nguyen TN, Gidda SK, ElBadawi-Sidhu M, Lambrecht JA, McCarty DR, Downs DM, Cooper AJ, Fiehn O, Mullen RT, Hanson AD. PMID: 25070638; PMCID: PMC4145128.
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    283. Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. Sci Rep. 2014 Jul 28; 4:5809. Blekhman R, Perry GH, Shahbaz S, Fiehn O, Clark AG, Gilad Y. PMID: 25069065; PMCID: PMC4894427.
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    284. Metabolomic analysis using porcine skin: a pilot study of analytical techniques. Dermatol Online J. 2014 Jun 15; 20(6). Wu J, Fiehn O, Armstrong AW. PMID: 24945638.
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    285. Exploration of polar lipid accumulation profiles in Euglena gracilis using LipidBlast, an MS/MS spectral library constructed in silico. Biosci Biotechnol Biochem. 2014; 78(1):14-8. Ogawa T, Furuhashi T, Okazawa A, Nakai R, Nakazawa M, Kind T, Fiehn O, Kanaya S, Arita M, Ohta D. PMID: 25036478.
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    286. Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose? Circ Cardiovasc Genet. 2014 Apr; 7(2):199-205. Cooper-Dehoff RM, Hou W, Weng L, Baillie RA, Beitelshees AL, Gong Y, Shahin MH, Turner ST, Chapman A, Gums JG, Boyle SH, Zhu H, Wikoff WR, Boerwinkle E, Fiehn O, Frye RF, Kaddurah-Daouk R, Johnson JA. PMID: 24627569; PMCID: PMC4050976.
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    287. Plants utilize a highly conserved system for repair of NADH and NADPH hydrates. Plant Physiol. 2014 May; 165(1):52-61. Niehaus TD, Richardson LG, Gidda SK, ElBadawi-Sidhu M, Meissen JK, Mullen RT, Fiehn O, Hanson AD. PMID: 24599492; PMCID: PMC4012604.
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    288. Detection of Huanglongbing disease using differential mobility spectrometry. Anal Chem. 2014 Mar 04; 86(5):2481-8. Aksenov AA, Pasamontes A, Peirano DJ, Zhao W, Dandekar AM, Fiehn O, Ehsani R, Davis CE. PMID: 24484549.
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    289. Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin. PLoS One. 2014; 9(1):e84260. Campbell C, Grapov D, Fiehn O, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Gustafson MB, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Hoppel CL, Meissen JK, Take K, Adams SH. PMID: 24416208; PMCID: PMC3885560.
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    292. Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway. PLoS One. 2013; 8(7):e68283. Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R, Pharmacometabolomics Research Network. PMID: 23874572; PMCID: PMC3714282.
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    295. Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging. Acta Neuropathol Commun. 2013 Jun 27; 1:28. Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, Reif DM, Appleby DH, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Arnold SE. PMID: 24252434; PMCID: PMC3893491.
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    296. A new metabolomic workflow for early detection of Alzheimer's disease. J Chromatogr A. 2013 Aug 09; 1302:65-71. Ibáñez C, Simó C, Barupal DK, Fiehn O, Kivipelto M, Cedazo-Mínguez A, Cifuentes A. PMID: 23827464.
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    297. Iron-dependent modifications of the flower transcriptome, proteome, metabolome, and hormonal content in an Arabidopsis ferritin mutant. J Exp Bot. 2013 Jul; 64(10):2665-88. Sudre D, Gutierrez-Carbonell E, Lattanzio G, Rellán-Álvarez R, Gaymard F, Wohlgemuth G, Fiehn O, Alvarez-Fernández A, Zamarreño AM, Bacaicoa E, Duy D, García-Mina JM, Abadía J, Philippar K, López-Millán AF, Briat JF. PMID: 23682113; PMCID: PMC3697946.
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    298. Pharmacometabolomics reveals racial differences in response to atenolol treatment. PLoS One. 2013; 8(3):e57639. Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R, Pharmacometabolomics Research Network. PMID: 23536766; PMCID: PMC3594230.
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    299. Metabolic acclimation to excess light intensity in Chlamydomonas reinhardtii. Plant Cell Environ. 2013 Jul; 36(7):1391-405. Davis MC, Fiehn O, Durnford DG. PMID: 23346954.
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    300. Evaluation and optimization of metabolome sample preparation methods for Saccharomyces cerevisiae. Anal Chem. 2013 Feb 19; 85(4):2169-76. Kim S, Lee DY, Wohlgemuth G, Park HS, Fiehn O, Kim KH. PMID: 23289506.
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    301. Metabolomic response of Chlamydomonas reinhardtii to the inhibition of target of rapamycin (TOR) by rapamycin. J Microbiol Biotechnol. 2013; 23(7):923-31. Lee DY, Fiehn O. PMID: 23727803.
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    302. Metabolite profiling of Arabidopsis inoculated with Alternaria brassicicola reveals that ascorbate reduces disease severity. Mol Plant Microbe Interact. 2012 Dec; 25(12):1628-38. Botanga CJ, Bethke G, Chen Z, Gallie DR, Fiehn O, Glazebrook J. PMID: 23134520.
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    303. Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism. PLoS One. 2012; 7(10):e46770. Meissen JK, Yuen BT, Kind T, Riggs JW, Barupal DK, Knoepfler PS, Fiehn O. PMID: 23077522; PMCID: PMC3471894.
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    304. Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study. BMC Genomics. 2012 Jul 23; 13:334. Budczies J, Denkert C, Müller BM, Brockmöller SF, Klauschen F, Györffy B, Dietel M, Richter-Ehrenstein C, Marten U, Salek RM, Griffin JL, Hilvo M, Orešic M, Wohlgemuth G, Fiehn O. PMID: 22823888; PMCID: PMC3430598.
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    305. System response of metabolic networks in Chlamydomonas reinhardtii to total available ammonium. Mol Cell Proteomics. 2012 Oct; 11(10):973-88. Lee DY, Park JJ, Barupal DK, Fiehn O. PMID: 22787274; PMCID: PMC3494149.
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    306. Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. PLoS One. 2012; 7(7):e38386. Trupp M, Zhu H, Wikoff WR, Baillie RA, Zeng ZB, Karp PD, Fiehn O, Krauss RM, Kaddurah-Daouk R. PMID: 22808006; PMCID: PMC3392268.
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    307. Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids. Plant J. 2012 Aug; 71(4):669-83. Meyer RC, Witucka-Wall H, Becher M, Blacha A, Boudichevskaia A, Dörmann P, Fiehn O, Friedel S, von Korff M, Lisec J, Melzer M, Repsilber D, Schmidt R, Scholz M, Selbig J, Willmitzer L, Altmann T. PMID: 22487254.
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    308. Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation. Sci Transl Med. 2012 Jun 06; 4(137):137ra73. Ho PP, Kanter JL, Johnson AM, Srinagesh HK, Chang EJ, Purdy TM, van Haren K, Wikoff WR, Kind T, Khademi M, Matloff LY, Narayana S, Hur EM, Lindstrom TM, He Z, Fiehn O, Olsson T, Han X, Han MH, Steinman L, Robinson WH. PMID: 22674551; PMCID: PMC3953135.
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    309. MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity. BMC Bioinformatics. 2012 May 16; 13:99. Barupal DK, Haldiya PK, Wohlgemuth G, Kind T, Kothari SL, Pinkerton KE, Fiehn O. PMID: 22591066; PMCID: PMC3495401.
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    310. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. PLoS One. 2012; 7(5):e36637. Song IS, Lee DY, Shin MH, Kim H, Ahn YG, Park I, Kim KH, Kind T, Shin JG, Fiehn O, Liu KH. PMID: 22590580; PMCID: PMC3348126.
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    311. A systems approach implicates nuclear receptor targeting in the Atp7b(-/-) mouse model of Wilson's disease. Metallomics. 2012 Jul; 4(7):660-8. Wilmarth PA, Short KK, Fiehn O, Lutsenko S, David LL, Burkhead JL. PMID: 22565294; PMCID: PMC3695828.
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    312. Qualitative analysis of algal secretions with multiple mass spectrometric platforms. J Chromatogr A. 2012 Jun 29; 1244:139-47. Kind T, Meissen JK, Yang D, Nocito F, Vaniya A, Cheng YS, Vandergheynst JS, Fiehn O. PMID: 22608776; PMCID: PMC3746802.
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    313. Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery. Genome Med. 2012 Apr 30; 4(4):37. Denkert C, Bucher E, Hilvo M, Salek R, Orešic M, Griffin J, Brockmöller S, Klauschen F, Loibl S, Barupal DK, Budczies J, Iljin K, Nekljudova V, Fiehn O. PMID: 22546809; PMCID: PMC3446265.
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    314. Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenet Genomics. 2012 Apr; 22(4):247-53. Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N, Nakamura Y, Kubo M, Mushiroda T, Kaddurah-Daouk R, Mrazek DA, Weinshilboum RM. PMID: 22322242; PMCID: PMC3303952.
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    315. Metabolomics as a Hypothesis-Generating Functional Genomics Tool for the Annotation of Arabidopsis thaliana Genes of "Unknown Function". Front Plant Sci. 2012; 3:15. Quanbeck SM, Brachova L, Campbell AA, Guan X, Perera A, He K, Rhee SY, Bais P, Dickerson JA, Dixon P, Wohlgemuth G, Fiehn O, Barkan L, Lange I, Lange BM, Lee I, Cortes D, Salazar C, Shuman J, Shulaev V, Huhman DV, Sumner LW, Roth MR, Welti R, Ilarslan H, Wurtele ES, Nikolau BJ. PMID: 22645570; PMCID: PMC3355754.
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    316. Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling. J Proteome Res. 2012 Feb 03; 11(2):850-60. Brockmöller SF, Bucher E, Müller BM, Budczies J, Hilvo M, Griffin JL, Orešic M, Kallioniemi O, Iljin K, Loibl S, Darb-Esfahani S, Sinn BV, Klauschen F, Prinzler J, Bangemann N, Ismaeel F, Fiehn O, Dietel M, Denkert C. PMID: 22070544.
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    317. Anesthetic induction with guaifenesin and propofol in adult horses. Am J Vet Res. 2011 Dec; 72(12):1569-75. Brosnan RJ, Steffey EP, Escobar A, Palazoglu M, Fiehn O. PMID: 22126682.
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    318. Association genetics of the loblolly pine (Pinus taeda, Pinaceae) metabolome. New Phytol. 2012 Mar; 193(4):890-902. Eckert AJ, Wegrzyn JL, Cumbie WP, Goldfarb B, Huber DA, Tolstikov V, Fiehn O, Neale DB. PMID: 22129444.
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    319. Comparative effects of fructose and glucose on lipogenic gene expression and intermediary metabolism in HepG2 liver cells. PLoS One. 2011; 6(11):e26583. Hirahatake KM, Meissen JK, Fiehn O, Adams SH. PMID: 22096489; PMCID: PMC3214012.
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    320. Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply. Front Plant Sci. 2011; 2:66. Rellán-Álvarez R, El-Jendoubi H, Wohlgemuth G, Abadía A, Fiehn O, Abadía J, Alvarez-Fernández A. PMID: 22645546; PMCID: PMC3355808.
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    321. The volatile compound BinBase mass spectral database. BMC Bioinformatics. 2011 Aug 04; 12:321. Skogerson K, Wohlgemuth G, Barupal DK, Fiehn O. PMID: 21816034; PMCID: PMC3199763.
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    322. Applying in-silico retention index and mass spectra matching for identification of unknown metabolites in accurate mass GC-TOF mass spectrometry. Anal Chem. 2011 Aug 01; 83(15):5895-902. Kumari S, Stevens D, Kind T, Denkert C, Fiehn O. PMID: 21678983; PMCID: PMC3146571.
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    323. Extending biochemical databases by metabolomic surveys. J Biol Chem. 2011 Jul 08; 286(27):23637-43. Fiehn O, Barupal DK, Kind T. PMID: 21566124; PMCID: PMC3129143.
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    324. Metabolomic and transcriptomic changes induced by overnight (16 h) fasting in male and female Sprague-Dawley rats. Chem Res Toxicol. 2011 Apr 18; 24(4):481-7. Robertson DG, Ruepp SU, Stryker SA, Hnatyshyn SY, Shipkova PA, Aranibar N, Mcnaney CA, Fiehn O, Reily MD. PMID: 21381695.
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    325. Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. Arterioscler Thromb Vasc Biol. 2011 Jun; 31(6):1260-7. Wu D, Nishimura N, Kuo V, Fiehn O, Shahbaz S, Van Winkle L, Matsumura F, Vogel CF. PMID: 21441140; PMCID: PMC3098318.
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    326. Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. Cancer Res. 2011 May 01; 71(9):3236-45. Hilvo M, Denkert C, Lehtinen L, Müller B, Brockmöller S, Seppänen-Laakso T, Budczies J, Bucher E, Yetukuri L, Castillo S, Berg E, Nygren H, Sysi-Aho M, Griffin JL, Fiehn O, Loibl S, Richter-Ehrenstein C, Radke C, Hyötyläinen T, Kallioniemi O, Iljin K, Oresic M. PMID: 21415164.
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    327. Prognostic impact of AMP-activated protein kinase expression in ovarian carcinoma: correlation of protein expression and GC/TOF-MS-based metabolomics. Oncol Rep. 2011 Apr; 25(4):1005-12. Buckendahl AC, Budczies J, Fiehn O, Darb-Esfahani S, Kind T, Noske A, Weichert W, Sehouli J, Braicu E, Dietel M, Denkert C. PMID: 21271224.
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    328. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PLoS One. 2010 Dec 10; 5(12):e15234. Fiehn O, Garvey WT, Newman JW, Lok KH, Hoppel CL, Adams SH. PMID: 21170321; PMCID: PMC3000813.
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    329. Comparison of leaf and fruit metabolism in two tomato (Solanum lycopersicum L.) genotypes varying in total soluble solids. J Agric Food Chem. 2010 Nov 24; 58(22):11790-800. Luengwilai K, Fiehn OE, Beckles DM. PMID: 21033662.
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    330. Informatics for cross-sample analysis with comprehensive two-dimensional gas chromatography and high-resolution mass spectrometry (GCxGC-HRMS). Talanta. 2011 Jan 30; 83(4):1279-88. Reichenbach SE, Tian X, Tao Q, Ledford EB, Wu Z, Fiehn O. PMID: 21215864.
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    331. The Chemical Translation Service--a web-based tool to improve standardization of metabolomic reports. Bioinformatics. 2010 Oct 15; 26(20):2647-8. Wohlgemuth G, Haldiya PK, Willighagen E, Kind T, Fiehn O. PMID: 20829444; PMCID: PMC2951090.
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    332. Advances in structure elucidation of small molecules using mass spectrometry. Bioanal Rev. 2010 Dec; 2(1-4):23-60. Kind T, Fiehn O. PMID: 21289855; PMCID: PMC3015162.
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    333. Evaluation of sampling and extraction methodologies for the global metabolic profiling of Saccharophagus degradans. Anal Chem. 2010 Aug 01; 82(15):6660-6. Shin MH, Lee DY, Liu KH, Fiehn O, Kim KH. PMID: 20669998.
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    334. Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply. BMC Plant Biol. 2010 Jun 21; 10:120. Rellán-Alvarez R, Andaluz S, Rodríguez-Celma J, Wohlgemuth G, Zocchi G, Alvarez-Fernández A, Fiehn O, López-Millán AF, Abadía J. PMID: 20565974; PMCID: PMC3017792.
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    335. Divergent metabolome and proteome suggest functional independence of dual phloem transport systems in cucurbits. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13532-7. Zhang B, Tolstikov V, Turnbull C, Hicks LM, Fiehn O. PMID: 20566864; PMCID: PMC2922161.
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    336. Metabolomic and transcriptomic analysis of the rice response to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae. Metabolomics. 2010 Sep; 6(3):451-465. Sana TR, Fischer S, Wohlgemuth G, Katrekar A, Jung KH, Ronald PC, Fiehn O. PMID: 20676379; PMCID: PMC2899020.
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    337. Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. BMC Biotechnol. 2010 May 21; 10:40. Barupal DK, Kind T, Kothari SL, Lee DY, Fiehn O. PMID: 20492649; PMCID: PMC2883956.
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    338. Determination of elemental compositions by gas chromatography/time-of-flight mass spectrometry using chemical and electron ionization. Rapid Commun Mass Spectrom. 2010 Apr 30; 24(8):1172-80. Abate S, Ahn YG, Kind T, Cataldi TR, Fiehn O. PMID: 20301109; PMCID: PMC6438842.
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    339. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. PLoS One. 2010 Mar 24; 5(3):e9834. Seifert EL, Fiehn O, Bezaire V, Bickel DR, Wohlgemuth G, Adams SH, Harper ME. PMID: 20352092; PMCID: PMC2844415.
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    340. Impact of genetics and environment on the metabolite composition of maize grain. J Agric Food Chem. 2010 Mar 24; 58(6):3600-10. Skogerson K, Harrigan GG, Reynolds TL, Halls SC, Ruebelt M, Iandolino A, Pandravada A, Glenn KC, Fiehn O. PMID: 20158212.
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    341. Global metabolite profiling of agarose degradation by Saccharophagus degradans 2-40. N Biotechnol. 2010 May 31; 27(2):156-68. Shin MH, Lee DY, Wohlgemuth G, Choi IG, Fiehn O, Kim KH. PMID: 20215059.
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    342. Global metabolic profiling of plant cell wall polysaccharide degradation by Saccharophagus degradans. Biotechnol Bioeng. 2010 Feb 15; 105(3):477-88. Shin MH, Lee DY, Skogerson K, Wohlgemuth G, Choi IG, Fiehn O, Kim KH. PMID: 19806675.
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    343. PlantMetabolomics.org: a web portal for plant metabolomics experiments. Plant Physiol. 2010 Apr; 152(4):1807-16. Bais P, Moon SM, He K, Leitao R, Dreher K, Walk T, Sucaet Y, Barkan L, Wohlgemuth G, Roth MR, Wurtele ES, Dixon P, Fiehn O, Lange BM, Shulaev V, Sumner LW, Welti R, Nikolau BJ, Rhee SY, Dickerson JA. PMID: 20147492; PMCID: PMC2850039.
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    344. A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease. Am J Physiol Renal Physiol. 2010 Apr; 298(4):F909-22. Taylor SL, Ganti S, Bukanov NO, Chapman A, Fiehn O, Osier M, Kim K, Weiss RH. PMID: 20130118; PMCID: PMC2853321.
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    345. Analysis of early host responses for asymptomatic disease detection and management of specialty crops. Crit Rev Immunol. 2010; 30(3):277-89. Dandekar AM, Martinelli F, Davis CE, Bhushan A, Zhao W, Fiehn O, Skogerson K, Wohlgemuth G, D'Souza R, Roy S, Reagan RL, Lin D, Cary R, Pardington P, Gupta G. PMID: 20370635.
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    346. FiehnLib: mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Anal Chem. 2009 Dec 15; 81(24):10038-48. Kind T, Wohlgemuth G, Lee DY, Lu Y, Palazoglu M, Shahbaz S, Fiehn O. PMID: 19928838; PMCID: PMC2805091.
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    347. What are the obstacles for an integrated system for comprehensive interpretation of cross-platform metabolic profile data? Bioanalysis. 2009 Dec; 1(9):1511-4. Kind T, Fiehn O. PMID: 21083097.
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    348. Software platform virtualization in chemistry research and university teaching. J Cheminform. 2009 Nov 16; 1:18. Kind T, Leamy T, Leary JA, Fiehn O. PMID: 20150997; PMCID: PMC2820496.
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    349. Assessment of metabolome annotation quality: a method for evaluating the false discovery rate of elemental composition searches. PLoS One. 2009 Oct 16; 4(10):e7490. Matsuda F, Shinbo Y, Oikawa A, Hirai MY, Fiehn O, Kanaya S, Saito K. PMID: 19847304; PMCID: PMC2761541.
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    350. Human gut microbiome adopts an alternative state following small bowel transplantation. Proc Natl Acad Sci U S A. 2009 Oct 06; 106(40):17187-92. Hartman AL, Lough DM, Barupal DK, Fiehn O, Fishbein T, Zasloff M, Eisen JA. PMID: 19805153; PMCID: PMC2746123.
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    351. Gene regulation in parthenocarpic tomato fruit. J Exp Bot. 2009; 60(13):3873-90. Martinelli F, Uratsu SL, Reagan RL, Chen Y, Tricoli D, Fiehn O, Rocke DM, Gasser CS, Dandekar AM. PMID: 19700496; PMCID: PMC2736898.
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    352. Comparison of gas chromatography-coupled time-of-flight mass spectrometry and 1H nuclear magnetic resonance spectroscopy metabolite identification in white wines from a sensory study investigating wine body. J Agric Food Chem. 2009 Aug 12; 57(15):6899-907. Skogerson K, Runnebaum R, Wohlgemuth G, de Ropp J, Heymann H, Fiehn O. PMID: 19588931.
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    353. Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics. 2009 Dec; 5(4):435-458. Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal BS, van Ommen B, Pujos-Guillot E, Verheij E, Wishart D, Wopereis S. PMID: 20046865; PMCID: PMC2794347.
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    354. How large is the metabolome? A critical analysis of data exchange practices in chemistry. PLoS One. 2009; 4(5):e5440. Kind T, Scholz M, Fiehn O. PMID: 19415114; PMCID: PMC2673031.
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    355. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model. J Cardiovasc Pharmacol. 2008 Oct; 52(4):314-23. Ulu A, Davis BB, Tsai HJ, Kim IH, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. PMID: 18791465; PMCID: PMC2637359.
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    356. Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover. Mol Cancer. 2008 Sep 18; 7:72. Denkert C, Budczies J, Weichert W, Wohlgemuth G, Scholz M, Kind T, Niesporek S, Noske A, Buckendahl A, Dietel M, Fiehn O. PMID: 18799019; PMCID: PMC2569965.
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    357. Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol. 2008 Aug; 26(8):889-96. Taylor CF, Field D, Sansone SA, Aerts J, Apweiler R, Ashburner M, Ball CA, Binz PA, Bogue M, Booth T, Brazma A, Brinkman RR, Michael Clark A, Deutsch EW, Fiehn O, Fostel J, Ghazal P, Gibson F, Gray T, Grimes G, Hancock JM, Hardy NW, Hermjakob H, Julian RK, Kane M, Kettner C, Kinsinger C, Kolker E, Kuiper M, Le Novère N, Leebens-Mack J, Lewis SE, Lord P, Mallon AM, Marthandan N, Masuya H, McNally R, Mehrle A, Morrison N, Orchard S, Quackenbush J, Reecy JM, Robertson DG, Rocca-Serra P, Rodriguez H, Rosenfelder H, Santoyo-Lopez J, Scheuermann RH, Schober D, Smith B, Snape J, Stoeckert CJ, Tipton K, Sterk P, Untergasser A, Vandesompele J, Wiemann S. PMID: 18688244; PMCID: PMC2771753.
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    358. High quality metabolomic data for Chlamydomonas reinhardtii. Plant Methods. 2008 Apr 28; 4:7. Lee DY, Fiehn O. PMID: 18442406; PMCID: PMC2377246.
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    359. Highly efficient analysis of underivatized carbohydrates using monolithic-silica-based capillary hydrophilic interaction (HILIC) HPLC. Anal Bioanal Chem. 2008 Aug; 391(7):2533-42. Ikegami T, Horie K, Saad N, Hosoya K, Fiehn O, Tanaka N. PMID: 18415087.
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    360. Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry. Trends Analyt Chem. 2008 Mar; 27(3):261-269. Fiehn O. PMID: 18497891; PMCID: PMC2394193.
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    361. Quality control for plant metabolomics: reporting MSI-compliant studies. Plant J. 2008 Feb; 53(4):691-704. Fiehn O, Wohlgemuth G, Scholz M, Kind T, Lee DY, Lu Y, Moon S, Nikolau B. PMID: 18269577.
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    362. Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations. Plant J. 2008 Mar; 53(6):960-72. Lisec J, Meyer RC, Steinfath M, Redestig H, Becher M, Witucka-Wall H, Fiehn O, Törjék O, Selbig J, Altmann T, Willmitzer L. PMID: 18047556; PMCID: PMC2268983.
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    363. Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics. 2007 Sep; 3(3):211-221. Sumner LW, Amberg A, Barrett D, Beale MH, Beger R, Daykin CA, Fan TW, Fiehn O, Goodacre R, Griffin JL, Hankemeier T, Hardy N, Harnly J, Higashi R, Kopka J, Lane AN, Lindon JC, Marriott P, Nicholls AW, Reily MD, Thaden JJ, Viant MR. PMID: 24039616; PMCID: PMC3772505.
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    364. The metabolomics standards initiative. Nat Biotechnol. 2007 Aug; 25(8):846-8. MSI Board Members, Sansone SA, Fan T, Goodacre R, Griffin JL, Hardy NW, Kaddurah-Daouk R, Kristal BS, Lindon J, Mendes P, Morrison N, Nikolau B, Robertson D, Sumner LW, Taylor C, van der Werf M, van Ommen B, Fiehn O. PMID: 17687353.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
    365. Highly efficient monolithic silica capillary columns modified with poly(acrylic acid) for hydrophilic interaction chromatography. J Chromatogr A. 2007 Sep 14; 1164(1-2):198-205. Horie K, Ikegami T, Hosoya K, Saad N, Fiehn O, Tanaka N. PMID: 17689542.
      View in: PubMed   Mentions: 5     Fields:    
    366. Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors. BMC Bioinformatics. 2007 May 21; 8:162. Kose F, Budczies J, Holschneider M, Fiehn O. PMID: 17517139; PMCID: PMC1894643.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    367. Calculating optimal modulation periods to maximize the peak capacity in two-dimensional HPLC. Anal Chem. 2007 May 15; 79(10):3764-70. Horie K, Kimura H, Ikegami T, Iwatsuka A, Saad N, Fiehn O, Tanaka N. PMID: 17437330.
      View in: PubMed   Mentions: 12     Fields:    
    368. Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry. BMC Bioinformatics. 2007 Mar 27; 8:105. Kind T, Fiehn O. PMID: 17389044; PMCID: PMC1851972.
      View in: PubMed   Mentions: 260     Fields:    
    369. The metabolic signature related to high plant growth rate in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2007 Mar 13; 104(11):4759-64. Meyer RC, Steinfath M, Lisec J, Becher M, Witucka-Wall H, Törjék O, Fiehn O, Eckardt A, Willmitzer L, Selbig J, Altmann T. PMID: 17360597; PMCID: PMC1810331.
      View in: PubMed   Mentions: 156     Fields:    Translation:Animals
    370. A comprehensive urinary metabolomic approach for identifying kidney cancerr. Anal Biochem. 2007 Apr 15; 363(2):185-95. Kind T, Tolstikov V, Fiehn O, Weiss RH. PMID: 17316536.
      View in: PubMed   Mentions: 124     Fields:    Translation:Humans
    371. High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. J Biol Chem. 2007 Mar 16; 282(11):8343-55. Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F, Olson NE, Teupser D, Lutsenko S. PMID: 17205981.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    372. Application of liquid chromatography-mass spectrometry analysis in metabolomics: reversed-phase monolithic capillary chromatography and hydrophilic chromatography coupled to electrospray ionization-mass spectrometry. Methods Mol Biol. 2007; 358:141-55. Tolstikov VV, Fiehn O, Tanaka N. PMID: 17035685.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    373. SetupX--a public study design database for metabolomic projects. Pac Symp Biocomput. 2007; 169-80. Scholz M, Fiehn O. PMID: 17990490.
      View in: PubMed   Mentions: 78     Fields:    
    374. Metabolite profiling in blood plasma. Methods Mol Biol. 2007; 358:3-17. Fiehn O, Kind T. PMID: 17035677.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    375. Applications of metabolomics in agriculture. J Agric Food Chem. 2006 Nov 29; 54(24):8984-94. Dixon RA, Gang DR, Charlton AJ, Fiehn O, Kuiper HA, Reynolds TL, Tjeerdema RS, Jeffery EH, German JB, Ridley WP, Seiber JN. PMID: 17117782.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    376. Pathway analysis of kidney cancer using proteomics and metabolic profiling. Mol Cancer. 2006 Nov 24; 5:64. Perroud B, Lee J, Valkova N, Dhirapong A, Lin PY, Fiehn O, Kültz D, Weiss RH. PMID: 17123452; PMCID: PMC1665458.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    377. Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res. 2006 Nov 15; 66(22):10795-804. Denkert C, Budczies J, Kind T, Weichert W, Tablack P, Sehouli J, Niesporek S, Könsgen D, Dietel M, Fiehn O. PMID: 17108116.
      View in: PubMed   Mentions: 117     Fields:    Translation:Humans
    378. Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of Pept2-/- mice. Physiol Genomics. 2007 Feb 12; 28(3):301-10. Frey IM, Rubio-Aliaga I, Siewert A, Sailer D, Drobyshev A, Beckers J, de Angelis MH, Aubert J, Bar Hen A, Fiehn O, Eichinger HM, Daniel H. PMID: 17077276.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    379. Natural genetic variation of freezing tolerance in Arabidopsis. Plant Physiol. 2006 Sep; 142(1):98-112. Hannah MA, Wiese D, Freund S, Fiehn O, Heyer AG, Hincha DK. PMID: 16844837; PMCID: PMC1557609.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    380. Metabolomic database annotations via query of elemental compositions: mass accuracy is insufficient even at less than 1 ppm. BMC Bioinformatics. 2006 Apr 28; 7:234. Kind T, Fiehn O. PMID: 16646969; PMCID: PMC1464138.
      View in: PubMed   Mentions: 151     Fields:    
    381. Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results. Brief Bioinform. 2006 Jun; 7(2):159-65. Castle AL, Fiehn O, Kaddurah-Daouk R, Lindon JC. PMID: 16772263.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    382. Establishing reporting standards for metabolomic and metabonomic studies: a call for participation. OMICS. 2006; 10(2):158-63. Fiehn O, Kristal B, van Ommen B, Sumner LW, Sansone SA, Taylor C, Hardy N, Kaddurah-Daouk R. PMID: 16901221.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    383. Metabolite profiling in Arabidopsis. Methods Mol Biol. 2006; 323:439-47. Fiehn O. PMID: 16739598.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    384. Metabolite profiling of Chlamydomonas reinhardtii under nutrient deprivation. Plant Physiol. 2005 Dec; 139(4):1995-2005. Bölling C, Fiehn O. PMID: 16306140; PMCID: PMC1310576.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    385. Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. Proc Natl Acad Sci U S A. 2005 Oct 04; 102(40):14458-62. Catchpole GS, Beckmann M, Enot DP, Mondhe M, Zywicki B, Taylor J, Hardy N, Smith A, King RD, Kell DB, Fiehn O, Draper J. PMID: 16186495; PMCID: PMC1242293.
      View in: PubMed   Mentions: 71     Fields:    Translation:Animals
    386. Statistical methods for comparing comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry results: metabolomic analysis of mouse tissue extracts. J Chromatogr A. 2005 Sep 09; 1086(1-2):83-90. Shellie RA, Welthagen W, Zrostliková J, Spranger J, Ristow M, Fiehn O, Zimmermann R. PMID: 16130658.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    387. Metabolic profiling of laser microdissected vascular bundles of Arabidopsis thaliana. Plant Methods. 2005 Aug 18; 1(1):2. Schad M, Mungur R, Fiehn O, Kehr J. PMID: 16270917; PMCID: PMC1266046.
      View in: PubMed   Mentions: 32  
    388. Systems rebalancing of metabolism in response to sulfur deprivation, as revealed by metabolome analysis of Arabidopsis plants. Plant Physiol. 2005 May; 138(1):304-18. Nikiforova VJ, Kopka J, Tolstikov V, Fiehn O, Hopkins L, Hawkesford MJ, Hesse H, Hoefgen R. PMID: 15834012; PMCID: PMC1104185.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    389. Comparison of rapid liquid chromatography-electrospray ionization-tandem mass spectrometry methods for determination of glycoalkaloids in transgenic field-grown potatoes. Anal Biochem. 2005 Jan 15; 336(2):178-86. Zywicki B, Catchpole G, Draper J, Fiehn O. PMID: 15620882.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    390. A proposed framework for the description of plant metabolomics experiments and their results. Nat Biotechnol. 2004 Dec; 22(12):1601-6. Jenkins H, Hardy N, Beckmann M, Draper J, Smith AR, Taylor J, Fiehn O, Goodacre R, Bino RJ, Hall R, Kopka J, Lane GA, Lange BM, Liu JR, Mendes P, Nikolau BJ, Oliver SG, Paton NW, Rhee S, Roessner-Tunali U, Saito K, Smedsgaard J, Sumner LW, Wang T, Walsh S, Wurtele ES, Kell DB. PMID: 15583675.
      View in: PubMed   Mentions: 63     Fields:    Translation:Animals
    391. A prominent role for the CBF cold response pathway in configuring the low-temperature metabolome of Arabidopsis. Proc Natl Acad Sci U S A. 2004 Oct 19; 101(42):15243-8. Cook D, Fowler S, Fiehn O, Thomashow MF. PMID: 15383661; PMCID: PMC524070.
      View in: PubMed   Mentions: 195     Fields:    Translation:Animals
    392. Potential of metabolomics as a functional genomics tool. Trends Plant Sci. 2004 Sep; 9(9):418-25. Bino RJ, Hall RD, Fiehn O, Kopka J, Saito K, Draper J, Nikolau BJ, Mendes P, Roessner-Tunali U, Beale MH, Trethewey RN, Lange BM, Wurtele ES, Sumner LW. PMID: 15337491.
      View in: PubMed   Mentions: 153     Fields:    Translation:Animals
    393. Linking protein fractionation with multidimensional monolithic reversed-phase peptide chromatography/mass spectrometry enhances protein identification from complex mixtures even in the presence of abundant proteins. Rapid Commun Mass Spectrom. 2004; 18(6):643-50. Wienkoop S, Glinski M, Tanaka N, Tolstikov V, Fiehn O, Weckwerth W. PMID: 15052571.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    394. Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics. Anal Chem. 2003 Dec 01; 75(23):6737-40. Tolstikov VV, Lommen A, Nakanishi K, Tanaka N, Fiehn O. PMID: 14640754.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    395. Plant metabolomics: the missing link in functional genomics strategies. Plant Cell. 2002 Jul; 14(7):1437-40. Hall R, Beale M, Fiehn O, Hardy N, Sumner L, Bino R. PMID: 12119365; PMCID: PMC543394.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    396. Analysis of highly polar compounds of plant origin: combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry. Anal Biochem. 2002 Feb 15; 301(2):298-307. Tolstikov VV, Fiehn O. PMID: 11814300.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    397. Metabolomics--the link between genotypes and phenotypes. Plant Mol Biol. 2002 Jan; 48(1-2):155-71. Fiehn O. PMID: 11860207.
      View in: PubMed   Mentions: 1026     Fields:    Translation:Animals
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