Siddika Karakas

Title(s)Professor, Endocrinology, Diabetes, and Metabolism
SchoolSchool of Medicine
AddressG400 PSSB/UCDMC
CA 95817
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    1. New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men. Adv Clin Chem. 2018; 86:71-125. Karakas SE, Surampudi P. PMID: 30144842.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    2. NASH in Nondiabetic Endocrine Disorders. Metab Syndr Relat Disord. 2018 09; 16(7):315-320. Wang T, Yang W, Karakas S, Sarkar S. PMID: 29873585.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    4. (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. Redox Biol. 2018 04; 14:588-599. Cremonini E, Wang Z, Bettaieb A, Adamo AM, Daveri E, Mills DA, Kalanetra KM, Haj FG, Karakas S, Oteiza PI. PMID: 29154190; PMCID: PMC5691220.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    5. Women Also Use 5α-Reductase Inhibitors. JAMA Intern Med. 2017 11 01; 177(11):1701-1702. Karakas SE. PMID: 29114795.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. New biomarkers for diagnosis and management of polycystic ovary syndrome. Clin Chim Acta. 2017 Aug; 471:248-253. Karakas SE. PMID: 28624501.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    7. An ongoing measles outbreak in the Federation of Bosnia and Herzegovina, 2014 to 2015. Euro Surveill. 2015 Mar 05; 20(9). Hukic M, Ravlija J, Karakas S, Mulaomerovic M, Dedeic Ljubovic A, Salimovic-Besic I, Seremet M, Ahmetagic S, Comor A, Feric E. PMID: 25764186.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    8. Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial. J Nutr. 2015 Apr; 145(4):691-700. Piccolo BD, Comerford KB, Karakas SE, Knotts TA, Fiehn O, Adams SH. PMID: 25833773.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    9. Roles of circulating WNT-signaling proteins and WNT-inhibitors in human adiposity, insulin resistance, insulin secretion, and inflammation. Horm Metab Res. 2015 Feb; 47(2):152-7. Almario RU, Karakas SE. PMID: 25089371.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    10. The effects of weight loss on FABP4 and RBP4 in obese women with metabolic syndrome. Horm Metab Res. 2014 Mar; 46(3):224-31. Comerford KB, Buchan W, Karakas SE. PMID: 23979787.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    11. Refractory AIDS cholangiopathy: metabolic complications and the role of plasmapheresis. AIDS. 2013 Apr 24; 27(7):1193-4. Allen ME, Brown J, Karakas SE, Pollard RB. PMID: 23902924.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Free fatty acid binding protein-4 and retinol binding protein-4 in polycystic ovary syndrome: response to simvastatin and metformin therapies. Gynecol Endocrinol. 2013 May; 29(5):483-7. Karakas SE, Banaszewska B, Spaczynski RZ, Pawelczyk L, Duleba A. PMID: 23480783.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Utility of hemoglobin-A1C in nondiabetic women with polycystic ovary syndrome. Endocr Pract. 2013 Mar-Apr; 19(2):284-9. Mortada R, Comerford K, Kallail KJ, Karakas SE. PMID: 23529348.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Lignan content of the flaxseed influences its biological effects in healthy men and women. J Am Coll Nutr. 2013; 32(3):194-9. Almario RU, Karakas SE. PMID: 23885993.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    15. Lean mass and insulin resistance in women with polycystic ovary syndrome. Metabolism. 2012 Sep; 61(9):1256-60. Comerford KB, Almario RU, Kim K, Karakas SE. PMID: 22424820.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome. Metabolism. 2011 Dec; 60(12):1711-8. Vargas ML, Almario RU, Buchan W, Kim K, Karakas SE. PMID: 21640360; PMCID: PMC3210884.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    17. An outbreak of rubella in the Federation of Bosnia and Herzegovina between December 2009 and May 2010 indicates failure to vaccinate during wartime (1992-1995). Epidemiol Infect. 2012 Mar; 140(3):447-53. Hukic M, Hübschen JM, Seremet M, Salimovic-Besic I, Mulaomerovic M, Mehinovic N, Karakas S, Charpentier E, Muller CP. PMID: 21524344.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    18. In search of the "LINK": Acute Phase Serum Amyloid A. Atherosclerosis. 2011 Jun; 216(2):266-8. Karakas S, Mortada R, Fellow C. PMID: 21450291.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Differential effects of walnuts vs almonds on improving metabolic and endocrine parameters in PCOS. Eur J Clin Nutr. 2011 Mar; 65(3):386-93. Kalgaonkar S, Almario RU, Gurusinghe D, Garamendi EM, Buchan W, Kim K, Karakas SE. PMID: 21157477.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    20. The beneficial effects of α-cyclodextrin on blood lipids and weight loss in healthy humans. Obesity (Silver Spring). 2011 Jun; 19(6):1200-4. Comerford KB, Artiss JD, Jen KL, Karakas SE. PMID: 21127475.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    21. Translational nutrition research at UC Davis--the key role of the Clinical and Translational Science Center. Ann N Y Acad Sci. 2010 Mar; 1190:179-83. Kasim-Karakas S, Hyson D, Halsted C, van Loan M, Chedin E, Berglund L. PMID: 20388150; PMCID: PMC4806777.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Determinants of impaired fasting glucose versus glucose intolerance in polycystic ovary syndrome. Diabetes Care. 2010 Apr; 33(4):887-93. Karakas SE, Kim K, Duleba AJ. PMID: 20067969; PMCID: PMC2845047.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers. Metabolism. 2009 Jul; 58(7):1002-7. Karakas SE, Almario RU, Kim K. PMID: 19394980; PMCID: PMC2720822.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    24. In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake. Fertil Steril. 2010 Mar 01; 93(4):1192-9. Gurusinghe D, Gill S, Almario RU, Lee J, Horn WF, Keim NL, Kim K, Karakas SE. PMID: 19342030; PMCID: PMC2856447.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Effects of protein versus simple sugar intake on weight loss in polycystic ovary syndrome (according to the National Institutes of Health criteria). Fertil Steril. 2009 Jul; 92(1):262-70. Kasim-Karakas SE, Almario RU, Cunningham W. PMID: 18691705.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    26. Relation of nutrients and hormones in polycystic ovary syndrome. Am J Clin Nutr. 2007 Mar; 85(3):688-94. Kasim-Karakas SE, Cunningham WM, Tsodikov A. PMID: 17344488.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    27. The effect of weight loss and dietary fatty acids on inflammation. Curr Atheroscler Rep. 2006 Nov; 8(6):477-86. Devaraj S, Kasim-Karakas S, Jialal I. PMID: 17045074.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    28. Circulating bioactive androgens in midlife women. J Clin Endocrinol Metab. 2006 Nov; 91(11):4387-94. Chen J, Sowers MR, Moran FM, McConnell DS, Gee NA, Greendale GA, Whitehead C, Kasim-Karakas SE, Lasley BL. PMID: 16940455.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    29. Responses of inflammatory markers to a low-fat, high-carbohydrate diet: effects of energy intake. Am J Clin Nutr. 2006 Apr; 83(4):774-9. Kasim-Karakas SE, Tsodikov A, Singh U, Jialal I. PMID: 16600927.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    30. Metabolic and endocrine effects of a polyunsaturated fatty acid-rich diet in polycystic ovary syndrome. J Clin Endocrinol Metab. 2004 Feb; 89(2):615-20. Kasim-Karakas SE, Almario RU, Gregory L, Wong R, Todd H, Lasley BL. PMID: 14764771.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    31. An ad libitum, very low-fat diet results in weight loss and changes in nutrient intakes in postmenopausal women. J Am Diet Assoc. 2003 Dec; 103(12):1600-6. Mueller-Cunningham WM, Quintana R, Kasim-Karakas SE. . PMID: 14647085.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    32. Effects of prune consumption on the ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone. Am J Clin Nutr. 2002 Dec; 76(6):1422-7. Kasim-Karakas SE, Almario RU, Gregory L, Todd H, Wong R, Lasley BL. PMID: 12450912.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    33. Urinary excretion of catechin metabolites by human subjects after red wine consumption. Br J Nutr. 2002 Jan; 87(1):31-7. Donovan JL, Kasim-Karakas S, German JB, Waterhouse AL. PMID: 11895312.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    34. Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. Am J Clin Nutr. 2001 Jul; 74(1):72-9. Almario RU, Vonghavaravat V, Wong R, Kasim-Karakas SE. . PMID: 11451720.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    35. LC/ES-MS detection of hydroxycinnamates in human plasma and urine. J Agric Food Chem. 2001 Apr; 49(4):1747-50. Cremin P, Kasim-Karakas S, Waterhouse AL. PMID: 11308321.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    36. Changes in plasma lipoproteins during low-fat, high-carbohydrate diets: effects of energy intake. Am J Clin Nutr. 2000 Jun; 71(6):1439-47. Kasim-Karakas SE, Almario RU, Mueller WM, Peerson J. PMID: 10837283.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. Ethnic differences in the insulin resistance syndrome. Am J Clin Nutr. 2000 Mar; 71(3):670-1. Kasim-Karakas SE. . PMID: 10702157.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. (+)-Catechin in human plasma after ingestion of a single serving of reconstituted red wine. Am J Clin Nutr. 2000 Jan; 71(1):103-8. Bell JR, Donovan JL, Wong R, Waterhouse AL, German JB, Walzem RL, Kasim-Karakas SE. . PMID: 10617953.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCTClinical Trials
    39. Catechin is present as metabolites in human plasma after consumption of red wine. J Nutr. 1999 Sep; 129(9):1662-8. Donovan JL, Bell JR, Kasim-Karakas S, German JB, Walzem RL, Hansen RJ, Waterhouse AL. PMID: 10460201.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    40. Is it time for a wine trial? Am J Clin Nutr. 1998 Aug; 68(2):220-1. Waterhouse AL, German JB, Walzem RL, Hansen RJ, Kasim-Karakas SE. . PMID: 9701174.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. Dietary fat controversy: is it also applicable to children? Am J Clin Nutr. 1998 Jun; 67(6):1106-7. Kasim-Karakas SE. . PMID: 9625079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Effects of dietary fat restriction on particle size of plasma lipoproteins in postmenopausal women. Metabolism. 1997 Apr; 46(4):431-6. Kasim-Karakas SE, Lane E, Almario R, Mueller W, Walzem R. PMID: 9109849.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab. 1996 Dec; 81(12):4406-13. Havel PJ, Kasim-Karakas S, Mueller W, Johnson PR, Gingerich RL, Stern JS. PMID: 8954050.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    44. Gender differences in plasma leptin concentrations. Nat Med. 1996 Sep; 2(9):949-50. Havel PJ, Kasim-Karakas S, Dubuc GR, Mueller W, Phinney SD. PMID: 8782440.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    45. Effects of dietary carbohydrates on glucose and lipid metabolism in golden Syrian hamsters. J Lab Clin Med. 1996 Aug; 128(2):208-13. Kasim-Karakas SE, Vriend H, Almario R, Chow LC, Goodman MN. PMID: 8765217.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    46. Effects of omega-3 fatty acids on intravascular lipolysis of very-low-density lipoproteins in humans. Metabolism. 1995 Sep; 44(9):1223-30. Kasim-Karakas SE, Herrmann R, Almario R. PMID: 7666799.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    47. Impact of n-3 fatty acids on lipoprotein metabolism. Curr Opin Lipidol. 1995 Jun; 6(3):167-71. Kasim-Karakas SE. . PMID: 7648006.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    48. Changes in plasma lipoproteins during lipolysis in vivo in the hypertriglyceridemic state. Am J Clin Nutr. 1994 Feb; 59(2):378-83. Karakas SE, Khilnani S, Divens C, Almario R, Jen KL. PMID: 8310988.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    49. Effect of lovastatin on the secretion of very low density lipoprotein lipids and apolipoprotein B in the hypertriglyceridemic Zucker obese rat. Atherosclerosis. 1993 Dec; 104(1-2):147-52. Kasim SE, Elovson J, Khilnani S, Almario RU, Jen KL. PMID: 8141838.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    50. Verapamil prevents chronic renal failure-induced abnormalities in lipid metabolism. Am J Kidney Dis. 1993 Jul; 22(1):158-63. Akmal M, Perkins S, Kasim SE, Oh HY, Smogorzewski M, Massry SG. PMID: 8322779.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    51. Dietary marine fish oils and insulin action in type 2 diabetes. Ann N Y Acad Sci. 1993 Jun 14; 683:250-7. Kasim SE. PMID: 8352447.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women. Am J Clin Nutr. 1993 Feb; 57(2):146-53. Kasim SE, Martino S, Kim PN, Khilnani S, Boomer A, Depper J, Reading BA, Heilbrun LK. PMID: 8424382.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    53. Effect of the prostaglandin E1 analog enisoprost on glucose and lipid metabolism in patients with type II diabetes mellitus. Horm Metab Res. 1992 Apr; 24(4):176-80. Kasim SE, Moran M, Khilnani S, West MA, Jen KL. PMID: 1601393.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Mechanisms of triglyceride-lowering effect of an HMG-CoA reductase inhibitor in a hypertriglyceridemic animal model, the Zucker obese rat. J Lipid Res. 1992 Jan; 33(1):1-7. Kasim SE, LeBoeuf RC, Khilnani S, Tallapaka L, Dayananda D, Jen KL. PMID: 1552226.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    55. Relationships between the amount of weight loss and post-heparin lipoprotein lipase activity in patients with type II diabetes. Int J Obes. 1991 Dec; 15(12):833-40. Kasim SE, Darga LL, Holden JH, Khilnani S, Patton S, Jen KL, Lucas CP. PMID: 1794925.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    56. Amiodarone-induced changes in lipid metabolism. Horm Metab Res. 1990 Jul; 22(7):385-8. Kasim SE, Bagchi N, Brown TR, Khilnani S, Jackson K, Steinman RT, Lehmann MH. PMID: 2401448.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    57. Excess parathyroid hormone adversely affects lipid metabolism in chronic renal failure. Kidney Int. 1990 Mar; 37(3):854-8. Akmal M, Kasim SE, Soliman AR, Massry SG. PMID: 2313975.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    58. Effects of weight loss and weight maintenance on the serum lipids, lipoprotein lipase and hepatic triglyceride lipase activities in obese rats. Int J Obes. 1989; 13(3):279-88. Kasim S, Jen KL. PMID: 2767881.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    59. Effects of omega-3 fish oils on lipid metabolism, glycemic control, and blood pressure in type II diabetic patients. J Clin Endocrinol Metab. 1988 Jul; 67(1):1-5. Kasim SE, Stern B, Khilnani S, McLin P, Baciorowski S, Jen KL. PMID: 3379125.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    60. Achieving therapeutic goals in insulin-using diabetic patients with non-insulin-dependent diabetes mellitus. A weight reduction-exercise-oral agent approach. Am J Med. 1987 Sep 18; 83(3A):3-9. Lucas CP, Patton S, Stepke T, Kinhal V, Darga LL, Carroll-Michals L, Spafford TR, Kasim S. PMID: 3307404.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    61. Significance of hepatic triglyceride lipase activity in the regulation of serum high density lipoproteins in type II diabetes mellitus. J Clin Endocrinol Metab. 1987 Jul; 65(1):183-7. Kasim SE, Tseng K, Jen KL, Khilnani S. PMID: 3584394.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    62. Effect of amiodarone on serum lipids, lipoprotein lipase, and hepatic triglyceride lipase. Endocrinology. 1987 May; 120(5):1991-5. Kasim SE, Bagchi N, Brown TR, Khilnani S. PMID: 3569123.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    63. Cholesterol changes with aging: their nature and significance. Geriatrics. 1987 Mar; 42(3):73-6, 79-82. Kasim S. PMID: 3817481.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Cholesterol metabolism and aging. Am J Med. 1987 Jan 26; 82(1B):54-60. Kreisberg RA, Kasim S. PMID: 3544833.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    65. The effects of oral agent or insulin treatments on the plasma lipoproteins and the plasma lipoprotein lipase activator in diabetic patients. Horm Metab Res. 1986 Mar; 18(3):190-3. Kasim SE, LeBoeuf RC, Rockett MJ, Page J, Keyser AJ. PMID: 3516835.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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