Jian-Jian Li

Title(s)Professor, Radiation Oncology
SchoolSchool of Medicine
Address2700 Stockton Blvd
CA 95817
Phone916-703-5174
ORCID ORCID Icon0000-0003-3694-9675 Additional info
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    Collapse Biography 
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    University of Iowa, Iowa CityPh.D.12/1994radiation and cancer biology

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Mitochondrial bioenergetics is associated with aggressive breast cancer growth
    NIH R01CA213830Jan 1, 2017 - Dec 31, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511. Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591. Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. PMID: 32929084; PMCID: PMC7490264.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    3. Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy. iScience. 2020 Jun 26; 23(6):101215. Li JJ. PMID: 32512383; PMCID: PMC7260547.
      View in: PubMed   Mentions: 6  
    4. Rab25-Mediated EGFR Recycling Causes Tumor Acquired Radioresistance. iScience. 2020 Apr 24; 23(4):100997. Zhang L, Xie B, Qiu Y, Jing D, Zhang J, Duan Y, Li Z, Fan M, He J, Qiu Y, Tan R, Li JJ, Sun LQ. PMID: 32252020; PMCID: PMC7132159.
      View in: PubMed   Mentions: 2  
    5. Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo. Nat Nanotechnol. 2020 02; 15(2):145-153. Zhang L, Jing D, Jiang N, Rojalin T, Baehr CM, Zhang D, Xiao W, Wu Y, Cong Z, Li JJ, Li Y, Wang L, Lam KS. PMID: 31988501; PMCID: PMC7147967.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    6. Multiple Dynamics in Tumor Microenvironment Under Radiotherapy. Adv Exp Med Biol. 2020; 1263:175-202. Huang J, Li JJ. PMID: 32588328.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade. Dev Cell. 2020 01 27; 52(2):196-209.e9. Liu L, Xie B, Fan M, Candas-Green D, Jiang JX, Wei R, Wang Y, Chen HW, Hu Y, Li JJ. PMID: 31866205; PMCID: PMC6996588.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    8. Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation. Oncol Rep. 2020 01; 43(1):318-327. Duan Z, Andrews NP, Chen CZ, Fan M, Wang J, Shen J, Li JJ, Chen HW. PMID: 31789405.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. CPT1A/2-Mediated FAO Enhancement-A Metabolic Target in Radioresistant Breast Cancer. Front Oncol. 2019; 9:1201. Han S, Wei R, Zhang X, Jiang N, Fan M, Huang JH, Xie B, Zhang L, Miao W, Butler AC, Coleman MA, Vaughan AT, Wang Y, Chen HW, Liu J, Li JJ. PMID: 31803610; PMCID: PMC6873486.
      View in: PubMed   Mentions: 35  
    10. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 10 11; 10(1):4621. Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. PMID: 31604910; PMCID: PMC6789042.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    11. Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 06; 24:101189. Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. PMID: 30986607; PMCID: PMC6463934.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    12. Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma. Cancer Res. 2019 05 15; 79(10):2697-2708. Ma D, Liu S, Lal B, Wei S, Wang S, Zhan D, Zhang H, Lee RS, Gao P, Lopez-Bertoni H, Ying M, Li JJ, Laterra J, Wilson MA, Xia S. PMID: 30898840; PMCID: PMC8218246.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    13. Immune targets in the tumor microenvironment treated by radiotherapy. Theranostics. 2019; 9(5):1215-1231. Ozpiskin OM, Zhang L, Li JJ. PMID: 30867826; PMCID: PMC6401500.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    14. Targeted Profiling of Heat Shock Proteome in Radioresistant Breast Cancer Cells. Chem Res Toxicol. 2019 02 18; 32(2):326-332. Miao W, Fan M, Huang M, Li JJ, Wang Y. PMID: 30596229; PMCID: PMC6469359.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    15. Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance. Cancer Lett. 2019 02 28; 443:56-66. Xie B, Wang S, Jiang N, Li JJ. PMID: 30481564; PMCID: PMC6759061.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    16. Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer. Nano Lett. 2018 11 14; 18(11):7092-7103. Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS. PMID: 30339018; PMCID: PMC6501589.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    17. Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. Sci Rep. 2017 06 30; 7(1):4471. Navas-Moreno M, Mehrpouyan M, Chernenko T, Candas D, Fan M, Li JJ, Yan M, Chan JW. PMID: 28667313; PMCID: PMC5493633.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    18. Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity. Free Radic Biol Med. 2016 10; 99:110-119. Miller RC, Murley JS, Rademaker AW, Woloschak GE, Li JJ, Weichselbaum RR, Grdina DJ. PMID: 27427516; PMCID: PMC6764831.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    19. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes. Cancer Lett. 2016 08 10; 378(2):69-79. Wang J, Duan Z, Nugent Z, Zou JX, Borowsky AD, Zhang Y, Tepper CG, Li JJ, Fiehn O, Xu J, Kung HJ, Murphy LC, Chen HW. PMID: 27164560; PMCID: PMC7505026.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    20. All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy. BMC Complement Altern Med. 2016 Mar 31; 16:113. Yan Y, Li Z, Xu X, Chen C, Wei W, Fan M, Chen X, Li JJ, Wang Y, Huang J. PMID: 27036550; PMCID: PMC4815257.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    21. Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1. J Vis Exp. 2016 Feb 25; (108):53417. Candas D, Qin L, Fan M, Li JJ. PMID: 26967001; PMCID: PMC4828183.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. CDK1 Enhances Mitochondrial Bioenergetics for Radiation-Induced DNA Repair. Cell Rep. 2015 Dec 15; 13(10):2056-63. Qin L, Fan M, Candas D, Jiang G, Papadopoulos S, Tian L, Woloschak G, Grdina DJ, Li JJ. PMID: 26670043; PMCID: PMC4684969.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    23. Enhanced anti-colon cancer immune responses with modified eEF2-derived peptides. Cancer Lett. 2015 Dec 01; 369(1):112-23. Sun W, Wei X, Niu A, Ma X, Li JJ, Gao D. PMID: 26304717.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    24. CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther. 2015 Sep; 14(9):2090-102. Liu R, Fan M, Candas D, Qin L, Zhang X, Eldridge A, Zou JX, Zhang T, Juma S, Jin C, Li RF, Perks J, Sun LQ, Vaughan AT, Hai CX, Gius DR, Li JJ. PMID: 26141949; PMCID: PMC4560959.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    25. SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells. PLoS One. 2015; 10(6):e0129834. Cui Y, Qin L, Wu J, Qu X, Hou C, Sun W, Li S, Vaughan AT, Li JJ, Liu J. PMID: 26121691; PMCID: PMC4487898.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    26. Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect. PLoS One. 2015; 10(3):e0121046. Lu CL, Qin L, Liu HC, Candas D, Fan M, Li JJ. PMID: 25807077; PMCID: PMC4373728.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    27. NFκB and Survivin-Mediated Radio-Adaptive Response. Radiat Res. 2015 Apr; 183(4):391-7. Grdina DJ, Murley JS, Miller RC, Woloschak GE, Li JJ. PMID: 25763931.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    28. CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection. Free Radic Biol Med. 2015 Apr; 81:77-87. Jin C, Qin L, Shi Y, Candas D, Fan M, Lu CL, Vaughan AT, Shen R, Wu LS, Liu R, Li RF, Murley JS, Woloschak G, Grdina DJ, Li JJ. PMID: 25578653; PMCID: PMC4359946.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    29. Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells. Cancer Res. 2014 Dec 15; 74(24):7498-509. Candas D, Lu CL, Fan M, Chuang FY, Sweeney C, Borowsky AD, Li JJ. PMID: 25377473; PMCID: PMC4267894.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    30. Profiling global kinome signatures of the radioresistant MCF-7/C6 breast cancer cells using MRM-based targeted proteomics. J Proteome Res. 2015 Jan 02; 14(1):193-201. Guo L, Xiao Y, Fan M, Li JJ, Wang Y. PMID: 25341124; PMCID: PMC4286165.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    31. The network of epithelial-mesenchymal transition: potential new targets for tumor resistance. J Cancer Res Clin Oncol. 2015 Oct; 141(10):1697-713. Nantajit D, Lin D, Li JJ. PMID: 25270087; PMCID: PMC4382462.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    32. Blocking the formation of radiation-induced breast cancer stem cells. Oncotarget. 2014 Jun 15; 5(11):3743-55. Wang Y, Li W, Patel SS, Cong J, Zhang N, Sabbatino F, Liu X, Qi Y, Huang P, Lee H, Taghian A, Li JJ, DeLeo AB, Ferrone S, Epperly MW, Ferrone CR, Ly A, Brachtel EF, Wang X. PMID: 25003837; PMCID: PMC4116517.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    33. Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression. Dev Cell. 2014 Apr 28; 29(2):217-32. Wang Z, Fan M, Candas D, Zhang TQ, Qin L, Eldridge A, Wachsmann-Hogiu S, Ahmed KM, Chromy BA, Nantajit D, Duru N, He F, Chen M, Finkel T, Weinstein LS, Li JJ. PMID: 24746669; PMCID: PMC4156313.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    34. Breast cancer stem cells: Multiple capacities in tumor metastasis. Cancer Lett. 2014 Jul 10; 349(1):1-7. Geng SQ, Alexandrou AT, Li JJ. PMID: 24727284; PMCID: PMC4177877.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    35. Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients. PLoS One. 2014; 9(4):e93886. Gao D, Li C, Xie X, Zhao P, Wei X, Sun W, Liu HC, Alexandrou AT, Jones J, Zhao R, Li JJ. PMID: 24699863; PMCID: PMC3974849.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    36. Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response. Antioxid Redox Signal. 2014 Mar 20; 20(9):1463-80. Alexandrou AT, Li JJ. PMID: 24180340; PMCID: PMC3936506.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    37. Kinesin family deregulation coordinated by bromodomain protein ANCCA and histone methyltransferase MLL for breast cancer cell growth, survival, and tamoxifen resistance. Mol Cancer Res. 2014 Apr; 12(4):539-49. Zou JX, Duan Z, Wang J, Sokolov A, Xu J, Chen CZ, Li JJ, Chen HW. PMID: 24391143; PMCID: PMC4139106.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    38. Hyaluronan-CD44 interaction promotes oncogenic signaling, microRNA functions, chemoresistance, and radiation resistance in cancer stem cells leading to tumor progression. Adv Cancer Res. 2014; 123:255-75. Bourguignon LY, Shiina M, Li JJ. PMID: 25081533; PMCID: PMC6759082.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    39. Molecular mechanisms and treatment of radiation-induced lung fibrosis. Curr Drug Targets. 2013 Oct; 14(11):1347-56. Ding NH, Li JJ, Sun LQ. PMID: 23909719; PMCID: PMC4156316.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    40. MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx. Antioxid Redox Signal. 2014 Apr 01; 20(10):1599-617. Candas D, Li JJ. PMID: 23581847; PMCID: PMC3942709.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    41. A survivin-associated adaptive response in radiation therapy. Cancer Res. 2013 Jul 15; 73(14):4418-28. Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Li JJ, Woloschak GE, Weichselbaum RR. PMID: 23651635; PMCID: PMC3721325.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    42. Comparing radiation toxicities across species: an examination of radiation effects in Mus musculus and Peromyscus leucopus. Int J Radiat Biol. 2013 Jun; 89(6):391-400. Liu W, Haley B, Kwasny MJ, Li JJ, Grdina DJ, Paunesku T, Woloschak GE. PMID: 23362954.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsPHPublic Health
    43. The effects of radiation and dose-fractionation on cancer and non-tumor disease development. Int J Environ Res Public Health. 2012 Dec 18; 9(12):4688-703. Liu W, Haley BM, Kwasny MJ, Li JJ, Grdina DJ, Paunesku T, Woloschak GE. PMID: 23249856; PMCID: PMC3546784.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    44. A manganese superoxide dismutase (SOD2)-mediated adaptive response. Radiat Res. 2013 Feb; 179(2):115-24. Grdina DJ, Murley JS, Miller RC, Mauceri HJ, Sutton HG, Thirman MJ, Li JJ, Woloschak GE, Weichselbaum RR. PMID: 23237540; PMCID: PMC3594688.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    45. CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress. J Mol Cell Biol. 2013 Jun; 5(3):166-75. Candas D, Fan M, Nantajit D, Vaughan AT, Murley JS, Woloschak GE, Grdina DJ, Li JJ. PMID: 23243068; PMCID: PMC3656610.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    46. HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells. Clin Cancer Res. 2012 Dec 15; 18(24):6634-47. Duru N, Fan M, Candas D, Menaa C, Liu HC, Nantajit D, Wen Y, Xiao K, Eldridge A, Chromy BA, Li S, Spitz DR, Lam KS, Wicha MS, Li JJ. PMID: 23091114; PMCID: PMC3593096.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    47. Manganese superoxide dismutase interacts with a large scale of cellular and mitochondrial proteins in low-dose radiation-induced adaptive radioprotection. Free Radic Biol Med. 2012 Nov 15; 53(10):1838-47. Eldridge A, Fan M, Woloschak G, Grdina DJ, Chromy BA, Li JJ. PMID: 23000060; PMCID: PMC3494792.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    48. Potential use of nucleic acid-based agents in the sensitization of nasopharyngeal carcinoma to radiotherapy. Cancer Lett. 2012 Oct 01; 323(1):1-10. Zhang L, Yang L, Li JJ, Sun L. PMID: 22484469.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Germline stem cell gene PIWIL2 mediates DNA repair through relaxation of chromatin. PLoS One. 2011; 6(11):e27154. Yin DT, Wang Q, Chen L, Liu MY, Han C, Yan Q, Shen R, He G, Duan W, Li JJ, Wani A, Gao JX. PMID: 22110608; PMCID: PMC3217960.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    50. YY1 is a novel potential therapeutic target for the treatment of HPV infection-induced cervical cancer by arsenic trioxide. Int J Gynecol Cancer. 2011 Aug; 21(6):1097-104. He G, Wang Q, Zhou Y, Wu X, Wang L, Duru N, Kong X, Zhang P, Wan B, Sui L, Guo Q, Li JJ, Yu L. PMID: 21792014; PMCID: PMC3478771.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    51. SOD2-mediated effects induced by WR1065 and low-dose ionizing radiation on micronucleus formation in RKO human colon carcinoma cells. Radiat Res. 2011 Jan; 175(1):57-65. Murley JS, Kataoka Y, Miller RC, Li JJ, Woloschak G, Grdina DJ. PMID: 21175348; PMCID: PMC3071890.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    52. Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis. PLoS One. 2010 Oct 20; 5(10):e13406. Ye Y, Yin DT, Chen L, Zhou Q, Shen R, He G, Yan Q, Tong Z, Issekutz AC, Shapiro CL, Barsky SH, Lin H, Li JJ, Gao JX. PMID: 20975993; PMCID: PMC2958115.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    53. Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response. PLoS One. 2010 Aug 23; 5(8):e12341. Nantajit D, Fan M, Duru N, Wen Y, Reed JC, Li JJ. PMID: 20808790; PMCID: PMC2925892.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    54. Coactivation of ATM/ERK/NF-kappaB in the low-dose radiation-induced radioadaptive response in human skin keratinocytes. Free Radic Biol Med. 2009 Jun 01; 46(11):1543-50. Ahmed KM, Nantajit D, Fan M, Murley JS, Grdina DJ, Li JJ. PMID: 19324081; PMCID: PMC6759050.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    55. Proapoptotic function of integrin beta(3) in human hepatocellular carcinoma cells. Clin Cancer Res. 2009 Jan 01; 15(1):60-9. Wu Y, Zuo J, Ji G, Saiyin H, Liu X, Yin F, Cao N, Wen Y, Li JJ, Yu L. PMID: 19118033; PMCID: PMC3658616.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    56. NF-kappaB-mediated HER2 overexpression in radiation-adaptive resistance. Radiat Res. 2009 Jan; 171(1):9-21. Cao N, Li S, Wang Z, Ahmed KM, Degnan ME, Fan M, Dynlacht JR, Li JJ. PMID: 19138055; PMCID: PMC2659759.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    57. 64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics. Bioconjug Chem. 2008 Oct; 19(10):2008-22. Yang CT, Kim YS, Wang J, Wang L, Shi J, Li ZB, Chen X, Fan M, Li JJ, Liu S. PMID: 18763821; PMCID: PMC2637998.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    58. Cyclin D1 in low-dose radiation-induced adaptive resistance. Oncogene. 2008 Dec 04; 27(53):6738-48. Ahmed KM, Fan M, Nantajit D, Cao N, Li JJ. PMID: 18695676; PMCID: PMC6759063.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    59. Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinase-mediated apoptosis via NF-kappaB regulation. J Biol Chem. 2008 Jul 25; 283(30):21011-23. Wang Z, Cao N, Nantajit D, Fan M, Liu Y, Li JJ. PMID: 18508759; PMCID: PMC2475689.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    60. Maintenance of manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by repeated administration of the free thiol form of amifostine. Radiat Res. 2008 May; 169(5):495-505. Murley JS, Nantajit D, Baker KL, Kataoka Y, Li JJ, Grdina DJ. PMID: 18439041; PMCID: PMC2384167.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    61. NF-kappa B-mediated adaptive resistance to ionizing radiation. Free Radic Biol Med. 2008 Jan 01; 44(1):1-13. Ahmed KM, Li JJ. PMID: 17967430; PMCID: PMC2266095.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    62. ATM-NF-kappaB connection as a target for tumor radiosensitization. Curr Cancer Drug Targets. 2007 Jun; 7(4):335-42. Ahmed KM, Li JJ. PMID: 17979628; PMCID: PMC4156318.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    63. siRNA-mediated MDM2 inhibition sensitizes human lung cancer A549 cells to radiation. Int J Oncol. 2007 Jun; 30(6):1447-52. Guo W, Ahmed KM, Hui Y, Guo G, Li JJ. PMID: 17487365.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    64. Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats. Int J Mol Med. 2007 Jun; 19(6):865-73. Liu R, Ahmed KM, Nantajit D, Rosenthal FS, Hai CX, Li JJ. PMID: 17487418.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    65. Nuclear factor-kappaB and manganese superoxide dismutase mediate adaptive radioresistance in low-dose irradiated mouse skin epithelial cells. Cancer Res. 2007 Apr 01; 67(7):3220-8. Fan M, Ahmed KM, Coleman MC, Spitz DR, Li JJ. PMID: 17409430.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    66. Nuclear factor-kappaB p65 inhibits mitogen-activated protein kinase signaling pathway in radioresistant breast cancer cells. Mol Cancer Res. 2006 Dec; 4(12):945-55. Ahmed KM, Dong S, Fan M, Li JJ. PMID: 17189385.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    67. HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer. Anticancer Res. 2006 Nov-Dec; 26(6B):4235-43. Ahmed KM, Cao N, Li JJ. PMID: 17201139; PMCID: PMC3658609.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    68. The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage. Cancer Lett. 2006 Nov 08; 243(1):9-15. Zhou J, Lim CU, Li JJ, Cai L, Zhang Y. PMID: 16530324; PMCID: PMC3658610.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    69. Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. EMBO J. 2006 Mar 08; 25(5):1058-69. Liu H, Deng X, Shyu YJ, Li JJ, Taparowsky EJ, Hu CD. PMID: 16511568; PMCID: PMC1409714.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    70. The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells. Cancer Res. 2005 Nov 15; 65(22):10338-46. Wang T, Tamae D, LeBon T, Shively JE, Yen Y, Li JJ. PMID: 16288023.
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    71. Co-activation of ERK, NF-kappaB, and GADD45beta in response to ionizing radiation. J Biol Chem. 2005 Apr 01; 280(13):12593-601. Wang T, Hu YC, Dong S, Fan M, Tamae D, Ozeki M, Gao Q, Gius D, Li JJ. PMID: 15642734; PMCID: PMC4130153.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    72. A methylation profile of in vitro immortalized human cell lines. Int J Oncol. 2005 Jan; 26(1):275-85. Liu L, Zhang J, Bates S, Li JJ, Peehl DM, Rhim JS, Pfeifer GP. PMID: 15586250.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    73. Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res. 2004 Nov; 162(5):536-46. Murley JS, Kataoka Y, Cao D, Li JJ, Oberley LW, Grdina DJ. PMID: 15624308.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    74. Response of cyclin B1 to ionizing radiation: regulation by NF-kappaB and mitochondrial antioxidant enzyme MnSOD. Anticancer Res. 2004 Sep-Oct; 24(5A):2657-63. Ozeki M, Tamae D, Hou DX, Wang T, Lebon T, Spitz DR, Li JJ. PMID: 15517870; PMCID: PMC4139107.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    75. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology. Cancer Metastasis Rev. 2004 Aug-Dec; 23(3-4):311-22. Spitz DR, Azzam EI, Li JJ, Gius D. PMID: 15197331.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansAnimalsCells
    76. Adeno-associated virus Rep78/Rep68 promotes localized melting of the rep binding element in the absence of adenosine triphosphate. Chembiochem. 2004 Mar 05; 5(3):324-32. Lou HJ, Brister JR, Li JJ, Chen W, Muzyczka N, Tan W. PMID: 14997524.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    77. Expression of ErbB2 enhances radiation-induced NF-kappaB activation. Oncogene. 2004 Jan 15; 23(2):535-45. Guo G, Wang T, Gao Q, Tamae D, Wong P, Chen T, Chen WC, Shively JE, Wong JY, Li JJ. PMID: 14724581.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    78. p53 activation in chronic radiation-treated breast cancer cells: regulation of MDM2/p14ARF. Cancer Res. 2004 Jan 01; 64(1):221-8. Xia L, Paik A, Li JJ. PMID: 14729628.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    79. BZLF1 controlled by family repeat domain induces lytic cytotoxicity in Epstein-Barr virus-positive tumor cells. Anticancer Res. 2004 Jan-Feb; 24(1):67-74. Wang H, Zhao Y, Zeng L, Tang M, El-Deeb A, Li JJ, Cao Y. PMID: 15015577.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    80. Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms. Carcinogenesis. 2004 Jan; 25(1):29-36. Hou DX, Kai K, Li JJ, Lin S, Terahara N, Wakamatsu M, Fujii M, Young MR, Colburn N. PMID: 14514663.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    81. Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway. Int J Oncol. 2003 Apr; 22(4):829-33. Lin S, Li JJ, Fujii M, Hou DX. PMID: 12632075.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    82. Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol. 2003 Apr; 23(7):2362-78. Guo G, Yan-Sanders Y, Lyn-Cook BD, Wang T, Tamae D, Ogi J, Khaletskiy A, Li Z, Weydert C, Longmate JA, Huang TT, Spitz DR, Oberley LW, Li JJ. PMID: 12640121; PMCID: PMC150726.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    83. The role of NF-kappaB in the regulation of cell stress responses. Int Immunopharmacol. 2002 Oct; 2(11):1509-20. Wang T, Zhang X, Li JJ. PMID: 12433052.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    84. Human cytomegalovirus in neoplastic cells of Epstein-Barr virus negative Hodgkin's disease. Int J Oncol. 2002 Jul; 21(1):31-6. Huang G, Yan Q, Wang Z, Chen X, Zhang X, Guo Y, Li JJ. PMID: 12063546.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    85. STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells. Oncogene. 2002 Jun 06; 21(25):3949-60. Yu CY, Wang L, Khaletskiy A, Farrar WL, Larner A, Colburn NH, Li JJ. PMID: 12037677.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    86. Activation of nuclear factor kappaB in radioresistance of TP53-inactive human keratinocytes. Cancer Res. 2002 Feb 15; 62(4):1213-21. Chen X, Shen B, Xia L, Khaletzkiy A, Chu D, Wong JY, Li JJ. PMID: 11861406.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    87. Effector genes altered in MCF-7 human breast cancer cells after exposure to fractionated ionizing radiation. Radiat Res. 2001 Apr; 155(4):543-53. Li Z, Xia L, Lee LM, Khaletskiy A, Wang J, Wong JY, Li JJ. PMID: 11260656.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    88. Genes regulated in human breast cancer cells overexpressing manganese-containing superoxide dismutase. Free Radic Biol Med. 2001 Feb 01; 30(3):260-7. Li Z, Khaletskiy A, Wang J, Wong JY, Oberley LW, Li JJ. PMID: 11165872.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    89. Induced expression of dominant-negative c-jun downregulates NFkappaB and AP-1 target genes and suppresses tumor phenotype in human keratinocytes. Mol Carcinog. 2000 Nov; 29(3):159-69. Li JJ, Cao Y, Young MR, Colburn NH. PMID: 11108661.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    90. Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9827-32. Young MR, Li JJ, Rincón M, Flavell RA, Sathyanarayana BK, Hunziker R, Colburn N. PMID: 10449779; PMCID: PMC22295.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    91. Vanadate-induced activation of activator protein-1: role of reactive oxygen species. Carcinogenesis. 1999 Apr; 20(4):663-8. Ding M, Li JJ, Leonard SS, Ye JP, Shi X, Colburn NH, Castranova V, Vallyathan V. PMID: 10223197.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    92. Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation. Oncogene. 1998 Dec 31; 17(26):3493-8. Watts RG, Huang C, Young MR, Li JJ, Dong Z, Pennie WD, Colburn NH. PMID: 10030673.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    93. Inhibition of AP-1 and NF-kappaB by manganese-containing superoxide dismutase in human breast cancer cells. FASEB J. 1998 Dec; 12(15):1713-23. Li JJ, Oberley LW, Fan M, Colburn NH. PMID: 9837861.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    94. Expression of dominant negative Jun inhibits elevated AP-1 and NF-kappaB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes. Oncogene. 1998 May 28; 16(21):2711-21. Li JJ, Rhim JS, Schlegel R, Vousden KH, Colburn NH. PMID: 9652737.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    95. Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells. Carcinogenesis. 1998 May; 19(5):833-9. Li JJ, Colburn NH, Oberley LW. PMID: 9635871.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    96. Purification and identification of chemokines potentially involved in kidney-specific metastasis by a murine lymphoma variant: induction of migration and NFkappaB activation. Int J Cancer. 1998 Mar 16; 75(6):900-7. Wang JM, Chertov O, Proost P, Li JJ, Menton P, Xu L, Sozzani S, Mantovani A, Gong W, Schirrmacher V, Van Damme J, Oppenheim JJ. PMID: 9506536.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    97. Ethanol down-regulates the transcription of microsomal triglyceride transfer protein gene. FASEB J. 1997 Nov; 11(13):1145-52. Lin MC, Li JJ, Wang EJ, Princler GL, Kauffman FC, Kung HF. PMID: 9367349.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    98. Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res. 1997 Aug 15; 57(16):3569-76. Li JJ, Westergaard C, Ghosh P, Colburn NH. PMID: 9270030.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    99. Overexpression of manganese-containing superoxide dismutase confers resistance to the cytotoxicity of tumor necrosis factor alpha and/or hyperthermia. Cancer Res. 1997 May 15; 57(10):1991-8. Li JJ, Oberley LW. PMID: 9157996.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    100. Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element. Cancer Res. 1996 Feb 01; 56(3):483-9. Li JJ, Dong Z, Dawson MI, Colburn NH. PMID: 8564958.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    101. The use of RT-PCR to distinguish between plasmid MnSOD transcripts and endogenous MnSOD mRNA. Biochem Biophys Res Commun. 1995 Nov 13; 216(2):610-8. Li JJ, Domann F, Oberley LW. PMID: 7488155.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    102. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene. 1995 May 18; 10(10):1989-2000. Li JJ, Oberley LW, St Clair DK, Ridnour LA, Oberley TD. PMID: 7761099.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    103. Dual mechanisms for change in myocardial signal intensity by means of a single MR contrast medium: dependence on concentration and pulse sequence. Radiology. 1993 Jan; 186(1):175-82. Saeed M, Wendland MF, Masui T, Yu KK, Li JJ, Derugin N, Higgins CB. PMID: 8416560.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    104. Relationship between thermal tolerance and protein degradation in temperature-sensitive mouse cells. J Cell Physiol. 1992 May; 151(2):310-7. Li JJ, Dewey WC. PMID: 1572905.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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