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Richard J Bold

Title(s)Professor, Surgery
SchoolUniversity of California, Davis
Phone916-734-7269
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. ROR? is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 Oct 11; 10(1):4621. PMID: 31604910.
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    2. Chen JA, Esteghamat N, Kim EJ, Garcia G, Gong J, Fakih MG, Bold RJ, Cho MT. PD-1 Blockade in a Liver Transplant Recipient With Microsatellite Unstable Metastatic Colorectal Cancer and Hepatic Impairment. J Natl Compr Canc Netw. 2019 Sep 01; 17(9):1026-1030. PMID: 31487676.
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    3. Bateni SB, Gingrich AA, Hoch JS, Canter RJ, Bold RJ. Defining Value for Pancreatic Surgery in Early-Stage Pancreatic Cancer. JAMA Surg. 2019 Aug 21; e193019. PMID: 31433465.
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    4. Judge SJ, Lata-Arias K, Yanagisawa M, Darrow MA, Monjazeb AM, Kirane AR, Bold RJ, Canter RJ, Canter DJ. Morbidity, mortality and temporal trends in the surgical management of retroperitoneal sarcoma: An ACS-NSQIP follow up analysis. J Surg Oncol. 2019 Sep; 120(4):753-760. PMID: 31355444.
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    5. Alvarado MD, Mittendorf EA, Teshome M, Thompson AM, Bold RJ, Gittleman MA, Beitsch PD, Blair SL, Kivilaid K, Harmer QJ, Hunt KK. SentimagIC: A Non-inferiority Trial Comparing Superparamagnetic Iron Oxide Versus Technetium-99m and Blue Dye in the Detection of Axillary Sentinel Nodes in Patients with Early-Stage Breast Cancer. Ann Surg Oncol. 2019 Oct; 26(11):3510-3516. PMID: 31297674.
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    6. Gingrich AA, Bateni SB, Monjazeb AM, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Extremity soft tissue sarcoma in the elderly: Are we overtreating or undertreating this potentially vulnerable patient population? J Surg Oncol. 2019 Jun; 119(8):1087-1098. PMID: 30977916.
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    7. Bateni SB, Gingrich AA, Jeon SY, Hoch JS, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Clinical Outcomes and Costs Following Unplanned Excisions of Soft Tissue Sarcomas in the Elderly. J Surg Res. 2019 Jul; 239:125-135. PMID: 30825757.
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    8. Bateni SB, Davidson AJ, Arora M, Daly ME, Stewart SL, Bold RJ, Canter RJ, Sauder CAM. Is Breast-Conserving Therapy Appropriate for Male Breast Cancer Patients? A National Cancer Database Analysis. Ann Surg Oncol. 2019 Jul; 26(7):2144-2153. PMID: 30761438.
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    9. Whitney RL, Bell JF, Tancredi DJ, Romano PS, Bold RJ, Wun T, Joseph JG. Unplanned Hospitalization Among Individuals With Cancer in the Year After Diagnosis. J Oncol Pract. 2019 Jan; 15(1):e20-e29. PMID: 30523749.
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    10. Bateni SB, Gingrich AA, Stewart SL, Meyers FJ, Bold RJ, Canter RJ. Hospital utilization and disposition among patients with malignant bowel obstruction: a population-based comparison of surgical to medical management. BMC Cancer. 2018 Nov 26; 18(1):1166. PMID: 30477454.
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    11. Brown EG, Bateni SB, Burgess D, Li CS, Bold RJ. Interhospital Variability in Quality Outcomes of Pancreatic Surgery. J Surg Res. 2019 Mar; 235:453-458. PMID: 30691829.
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    12. Hausner SH, Bold RJ, Cheuy LY, Chew HK, Daly ME, Davis RA, Foster CC, Kim EJ, Sutcliffe JL. Preclinical Development and First-in-Human Imaging of the Integrin avß6 with [18F]avß6-Binding Peptide in Metastatic Carcinoma. Clin Cancer Res. 2019 Feb 15; 25(4):1206-1215. PMID: 30401687.
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    13. Tu MJ, Ho PY, Zhang QY, Jian C, Qiu JX, Kim EJ, Bold RJ, Gonzalez FJ, Bi H, Yu AM. Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models. Cancer Lett. 2019 02 01; 442:82-90. PMID: 30389433.
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    14. Olson JL, Bold RJ. Currently available first-line drug therapies for treating pancreatic cancer. Expert Opin Pharmacother. 2018 12; 19(17):1927-1940. PMID: 30325679.
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    15. Bateni SB, Olson JL, Hoch JS, Canter RJ, Bold RJ. Drivers of Cost for Pancreatic Surgery: It's Not About Hospital Volume. Ann Surg Oncol. 2018 Dec; 25(13):3804-3811. PMID: 30218244.
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    16. Bateni SB, Canter RJ, Meyers FJ, Galante JM, Bold RJ. Palliative Care Training and Decision-Making for Patients with Advanced Cancer: A Comparison of Surgeons and Medical Physicians. Surgery. 2018 Apr 27. PMID: 29709369.
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    17. Becker J, Woloszyn J, Bold R, Campbell MJ. The Adrenal Incidentaloma: An Opportunity to Improve Patient Care. J Gen Intern Med. 2018 03; 33(3):256-257. PMID: 29256090.
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    18. Yanagisawa M, Gingrich AA, Judge S, Li CS, Wang N, Thorpe SW, Kirane AR, Bold RJ, Monjazeb AM, Canter RJ. Serum C-reactive Protein and Neutrophil/Lymphocyte Ratio After Neoadjuvant Radiotherapy in Soft Tissue Sarcoma. Anticancer Res. 2018 03; 38(3):1491-1497. PMID: 29491077.
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    19. Unger J, Sun T, Chen YL, Phipps JE, Bold RJ, Darrow MA, Ma KL, Marcu L. Method for accurate registration of tissue autofluorescence imaging data with corresponding histology: a means for enhanced tumor margin assessment. J Biomed Opt. 2018 01; 23(1):1-11. PMID: 29297208.
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    20. Phipps JE, Gorpas D, Unger J, Darrow M, Bold RJ, Marcu L. Automated detection of breast cancer in resected specimens with fluorescence lifetime imaging. Phys Med Biol. 2017 12 14; 63(1):015003. PMID: 29099721.
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    21. Bateni SB, Bold RJ, Meyers FJ, Canter DJ, Canter RJ. Comparison of common risk stratification indices to predict outcomes among stage IV cancer patients with bowel obstruction undergoing surgery. J Surg Oncol. 2018 Mar; 117(3):479-487. PMID: 29044598.
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    22. Whitney RL, Bell JF, Tancredi DJ, Romano PS, Bold RJ, Joseph JG. Hospitalization Rates and Predictors of Rehospitalization Among Individuals With Advanced Cancer in the Year After Diagnosis. J Clin Oncol. 2017 Nov 01; 35(31):3610-3617. PMID: 28850290.
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    23. Gingrich AA, Bateni SB, Monjazeb AM, Darrow MA, Thorpe SW, Kirane AR, Bold RJ, Canter RJ. Neoadjuvant Radiotherapy is Associated with R0 Resection and Improved Survival for Patients with Extremity Soft Tissue Sarcoma Undergoing Surgery: A National Cancer Database Analysis. Ann Surg Oncol. 2017 Oct; 24(11):3252-3263. PMID: 28741123.
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    24. Reed SC, Bell JF, Whitney R, Lash R, Kim KK, Bold RJ, Joseph JG. Psychosocial outcomes in active treatment through survivorship. Psychooncology. 2018 01; 27(1):279-285. PMID: 28429466.
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    25. Park JS, Bateni SB, Bold RJ, Kirane AR, Canter DJ, Canter RJ. The modified frailty index to predict morbidity and mortality for retroperitoneal sarcoma resections. J Surg Res. 2017 09; 217:191-197. PMID: 28587892.
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    26. Bell JF, Whitney RL, Reed SC, Poghosyan H, Lash RS, Kim KK, Davis A, Bold RJ, Joseph JG. Systematic Review of Hospital Readmissions Among Patients With Cancer in the United States. Oncol Nurs Forum. 2017 03 01; 44(2):176-191. PMID: 28222076.
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    27. Lash RS, Bell JF, Reed SC, Poghosyan H, Rodgers J, Kim KK, Bold RJ, Joseph JG. A Systematic Review of Emergency Department Use Among Cancer Patients. Cancer Nurs. 2017 Mar/Apr; 40(2):135-144. PMID: 26925998.
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    28. Bold RJ. Biology Trumps Anatomic Location in Periampullary Cancers. JAMA Surg. 2017 01 01; 152(1):89. PMID: 27732696.
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    29. Bateni SB, David EA, Bold RJ, Cooke DT, Meyers FJ, Canter RJ. Lung resection is safe and feasible among stage IV cancer patients: An American College of Surgeons National Surgical Quality Improvement Program analysis. Surgery. 2017 05; 161(5):1307-1314. PMID: 28011006.
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    30. Brown EG, Anderson JE, Burgess D, Bold RJ, Farmer DL. Pediatric surgical readmissions: Are they truly preventable? J Pediatr Surg. 2017 Jan; 52(1):161-165. PMID: 27919406.
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    31. Bateni SB, Meyers FJ, Bold RJ, Canter RJ. Increased Rates of Prolonged Length of Stay, Readmissions, and Discharge to Care Facilities among Postoperative Patients with Disseminated Malignancy: Implications for Clinical Practice. PLoS One. 2016; 11(10):e0165315. PMID: 27780274.
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    32. Brown EG, Anderson JE, Burgess D, Bold RJ. Examining the "Halo Effect" of Surgical Care Within Health Systems. JAMA Surg. 2016 10 01; 151(10):983-984. PMID: 27367923.
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    33. Yuen NK, Li CS, Monjazeb AM, Borys D, Bold RJ, Canter RJ. Older Age Modifies Oncologic Outcome Following Radiotherapy in Soft-tissue Sarcoma: A Subtype-specific SEER Analysis. Anticancer Res. 2016 Apr; 36(4):1745-50. PMID: 27069154.
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    34. Kim KK, Bell JF, Bold R, Davis A, Ngo V, Reed SC, Joseph JG. A Personal Health Network for Chemotherapy Care Coordination: Evaluation of Usability Among Patients. Stud Health Technol Inform. 2016; 225:232-6. PMID: 27332197.
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    35. Dyer BA, Kahn LA, Matin M, Bold RJ, Tanaka MI, Monjazeb AM. Long-Term Progression-Free Survival in a Patient with Locally Advanced, Unresectable Pancreatic Adenocarcinoma. Cureus. 2015 Dec 15; 7(12):e406. PMID: 26824007.
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    36. Whitney RL, Bell JF, Reed SC, Lash R, Bold RJ, Kim KK, Davis A, Copenhaver D, Joseph JG. Predictors of financial difficulties and work modifications among cancer survivors in the United States. J Cancer Surviv. 2016 Apr; 10(2):241-50. PMID: 26188363.
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    37. Yuen NK, Li CS, Monjazeb AM, Borys D, Bold RJ, Canter RJ. Older age impacts radiotherapy-related outcomes in soft tissue sarcoma. J Surg Res. 2015 Dec; 199(2):494-504. PMID: 26163324.
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    38. Brown EG, Bold RJ. Hospital Readmissions: Are They Preventable? Adv Surg. 2015; 49:15-29. PMID: 26299488.
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    39. Bateni SB, Meyers FJ, Bold RJ, Canter RJ. Current perioperative outcomes for patients with disseminated cancer. J Surg Res. 2015 Jul; 197(1):118-25. PMID: 25911950.
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    40. Kim EJ, Semrad TJ, Bold RJ. Phase II clinical trials on investigational drugs for the treatment of pancreatic cancers. Expert Opin Investig Drugs. 2015 Jun; 24(6):781-94. PMID: 25809274.
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    41. Daylami R, Muilenburg DJ, Virudachalam S, Bold RJ. Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. J Exp Clin Cancer Res. 2014 Dec 12; 33:102. PMID: 25499121.
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    42. Brown EG, Canter RJ, Bold RJ. Preoperative CA 19-9 kinetics as a prognostic variable in radiographically resectable pancreatic adenocarcinoma. J Surg Oncol. 2015 Mar; 111(3):293-8. PMID: 25330934.
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    43. Brown EG, Burgess D, Li CS, Canter RJ, Bold RJ. Hospital readmissions: necessary evil or preventable target for quality improvement. Ann Surg. 2014 Oct; 260(4):583-9; discussion 589-91. PMID: 25203874.
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    44. Mayadev J, Einck J, Elson S, Rugo H, Hwang S, Bold R, Daroui P, McCloskey S, Yashar C, Kim D, Fowble B. Practice patterns in the delivery of radiation therapy after mastectomy among the University of California Athena Breast Health Network. Clin Breast Cancer. 2015 Feb; 15(1):43-7. PMID: 25245425.
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    45. Changou CA, Chen YR, Xing L, Yen Y, Chuang FY, Cheng RH, Bold RJ, Ann DK, Kung HJ. Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy. Proc Natl Acad Sci U S A. 2014 Sep 30; 111(39):14147-52. PMID: 25122679.
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    46. Brown EG, Yang A, Canter RJ, Bold RJ. Outcomes of pancreaticoduodenectomy: where should we focus our efforts on improving outcomes? JAMA Surg. 2014 Jul; 149(7):694-9. PMID: 24849180.
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    47. Shah DR, Bold RJ, Yang AD, Khatri VP, Martinez SR, Canter RJ. Relative value units poorly correlate with measures of surgical effort and complexity. J Surg Res. 2014 Aug; 190(2):465-70. PMID: 24953983.
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    48. Whitney RL, Bell JF, Bold RJ, Joseph JG. Mental health needs and service use in a national sample of adult cancer survivors in the USA: has psychosocial care improved? Psychooncology. 2015 Jan; 24(1):80-8. PMID: 24818821.
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    49. Muilenburg D, Parsons C, Coates J, Virudachalam S, Bold RJ. Role of autophagy in apoptotic regulation by Akt in pancreatic cancer. Anticancer Res. 2014 Feb; 34(2):631-7. PMID: 24510992.
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    50. Mayadev J, Daly M, Chen A, Bold R, Chew H. The potential role of radiation therapy to the primary site of disease in stage IV breast cancer presenting with synchronous metastasis. Clin Breast Cancer. 2014 Feb; 14(1):10-2. PMID: 24183416.
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    51. Shah DR, Martinez SR, Canter RJ, Yang AD, Bold RJ, Khatri VP. Comparative morbidity and mortality from cervical or thoracic esophageal anastomoses. J Surg Oncol. 2013 Dec; 108(7):472-6. PMID: 24108568.
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    52. Canter RJ, Smith CA, Martinez SR, Goodnight JE, Bold RJ, Wisner DH. Extremity soft tissue tumor surgery by surgical specialty: a comparison of case volume among oncology and non-oncology-designated surgeons. J Surg Oncol. 2013 Sep; 108(3):142-7. PMID: 23893351.
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    53. Bold RJ. Re: CA 19-9 in potentially resectable pancreatic cancer: perspective to adjust surgical and preoperative therapy. Ann Surg Oncol. 2013 Jul; 20(7):2108-10. PMID: 23563959.
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    54. Changou CA, Wolfson DL, Ahluwalia BS, Bold RJ, Kung HJ, Chuang FY. Quantitative analysis of autophagy using advanced 3D fluorescence microscopy. J Vis Exp. 2013 May 03; (75):e50047. PMID: 23665532.
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    55. Chae AW, Vandewalker KM, Li YJ, Beckett LA, Ramsamooj R, Bold RJ, Khatri VP. Quantitation of sentinel node metastatic burden and Her-2/neu over-expression accurately predicts residual axillary nodal involvement and extranodal disease in breast cancer. Eur J Surg Oncol. 2013 Jun; 39(6):627-33. PMID: 23523315.
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    56. Shah DR, Brown E, Russo JE, Li CS, Martinez SR, Coates JM, Bold RJ, Canter RJ. Negligible effect of perioperative epidural analgesia among patients undergoing elective gastric and pancreatic resections. J Gastrointest Surg. 2013 Apr; 17(4):660-7. PMID: 23345053.
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    57. Shah DR, Wang H, Bold RJ, Yang X, Martinez SR, Yang AD, Khatri VP, Wisner DH, Canter RJ. Nomograms to predict risk of in-hospital and post-discharge venous thromboembolism after abdominal and thoracic surgery: an American College of Surgeons National Surgical Quality Improvement Program analysis. J Surg Res. 2013 Jul; 183(1):462-71. PMID: 23298949.
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    58. Shah DR, Canter RJ, Khatri VP, Bold RJ, Yang AD, Martinez SR. Utilization of sentinel lymph node biopsy in patients with ductal carcinoma in situ undergoing mastectomy. Ann Surg Oncol. 2013 Jan; 20(1):24-30. PMID: 23054103.
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    59. Bold RJ. Is palpation in the operating room the best method for surgical planning? Arch Surg. 2012 Sep; 147(9):875. PMID: 22987186.
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    60. Shah D, Borys D, Martinez SR, Li CS, Tamurian RM, Bold RJ, Monjazeb A, Canter RJ. Complete pathologic response to neoadjuvant radiotherapy is predictive of oncological outcome in patients with soft tissue sarcoma. Anticancer Res. 2012 Sep; 32(9):3911-5. PMID: 22993336.
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    61. Shah DR, Galante JM, Bold RJ, Canter RJ, Martinez SR. Text messaging among residents and faculty in a university general surgery residency program: prevalence, purpose, and patient care. J Surg Educ. 2013 Nov-Dec; 70(6):826-34. PMID: 24209663.
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    62. Martinez SR, Shah DR, Tseng WH, Canter RJ, Bold RJ. Rural-urban disparities in use of post-lumpectomy radiation. Med Oncol. 2012 Dec; 29(5):3250-7. PMID: 22684693.
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    63. Shah DR, Canter RJ, Khatri VP, Bold RJ, Martinez SR. Utilization of lymph node assessment in patients with ductal carcinoma in situ treated with lumpectomy. J Surg Res. 2012 Sep; 177(1):e21-6. PMID: 22482771.
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    64. Martinez SR, Tseng WH, Shah DR, Canter RJ, Bold RJ. Urban and non-urban disparities in the use of post-mastectomy radiation for breast cancer. Med Oncol. 2012 Sep; 29(3):1523-8. PMID: 21983860.
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    65. Tseng WH, Canter RJ, Bold RJ. Perioperative outcomes for open distal pancreatectomy: current benchmarks for comparison. J Gastrointest Surg. 2011 Nov; 15(11):2053-8. PMID: 21938560.
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    66. Martinez SR, Beal SH, Canter RJ, Chen SL, Khatri VP, Bold RJ. Medullary carcinoma of the breast: a population-based perspective. Med Oncol. 2011 Sep; 28(3):738-44. PMID: 20390465.
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    67. Smith CA, Martinez SR, Tseng WH, Tamurian RM, Bold RJ, Borys D, Canter RJ. Predicting survival for well-differentiated liposarcoma: the importance of tumor location. J Surg Res. 2012 Jun 01; 175(1):12-7. PMID: 21920555.
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    68. Tseng WH, Yang X, Wang H, Martinez SR, Chen SL, Meyers FJ, Bold RJ, Canter RJ. Nomogram to predict risk of 30-day morbidity and mortality for patients with disseminated malignancy undergoing surgical intervention. Ann Surg. 2011 Aug; 254(2):333-8. PMID: 21677562.
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    69. Martinez SR, Tseng WH, Canter RJ, Chen AM, Chen SL, Bold RJ. Do radiation use disparities influence survival in patients with advanced breast cancer? Cancer. 2012 Jan 01; 118(1):196-204. PMID: 21692066.
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    70. Tseng WH, Jin L, Canter RJ, Martinez SR, Khatri VP, Gauvin J, Bold RJ, Wisner D, Taylor S, Chen SL. Surgical resident involvement is safe for common elective general surgery procedures. J Am Coll Surg. 2011 Jul; 213(1):19-26; discussion 26-8. PMID: 21493108.
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    71. Vanderveen KA, Canter RJ, Yin D, Cress RD, Bold RJ. Factors affecting treatment delivery and outcomes of patients with early-stage pancreatic adenocarcinoma. Pancreas. 2011 Apr; 40(3):480-2. PMID: 21412120.
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    72. Tseng WH, Martinez SR, Tamurian RM, Chen SL, Bold RJ, Canter RJ. Contiguous organ resection is safe in patients with retroperitoneal sarcoma: An ACS-NSQIP analysis. J Surg Oncol. 2011 Apr; 103(5):390-4. PMID: 21400521.
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    73. Tseng WH, Stevenson TR, Canter RJ, Chen SL, Khatri VP, Bold RJ, Martinez SR. Sacramento area breast cancer epidemiology study: use of postmastectomy breast reconstruction along the rural-to-urban continuum. Plast Reconstr Surg. 2010 Dec; 126(6):1815-24. PMID: 21124121.
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    74. Coates JM, Martinez SR, Bold RJ, Chen SL. Adjuvant radiation therapy is associated with improved survival for adenoid cystic carcinoma of the breast. J Surg Oncol. 2010 Sep 15; 102(4):342-7. PMID: 20589709.
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    75. Parsons CM, Muilenburg D, Bowles TL, Virudachalam S, Bold RJ. The role of Akt activation in the response to chemotherapy in pancreatic cancer. Anticancer Res. 2010 Sep; 30(9):3279-89. PMID: 20944098.
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    76. Martinez SR, Beal SH, Chen SL, Canter RJ, Khatri VP, Chen A, Bold RJ. Disparities in the use of radiation therapy in patients with local-regionally advanced breast cancer. Int J Radiat Oncol Biol Phys. 2010 Nov 01; 78(3):787-92. PMID: 20619550.
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    77. Bold RJ. Finding the problems before fixing them: the culture of perioperative safety. Arch Surg. 2010 Jun; 145(6):589. PMID: 20575191.
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    78. Muilenburg DJ, Coates JM, Virudachalam S, Bold RJ. Targeting Bcl-2-mediated cell death as a novel therapy in pancreatic cancer. J Surg Res. 2010 Oct; 163(2):276-81. PMID: 20452611.
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    79. Beal SH, Martinez SR, Canter RJ, Chen SL, Khatri VP, Bold RJ. Survival in 12,653 breast cancer patients with extensive axillary lymph node metastasis in the anthracycline era. Med Oncol. 2010 Dec; 27(4):1420-4. PMID: 20049562.
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    80. Canter RJ, Beal S, Borys D, Martinez SR, Bold RJ, Robbins AS. Interaction of histologic subtype and histologic grade in predicting survival for soft-tissue sarcomas. J Am Coll Surg. 2010 Feb; 210(2):191-198.e2. PMID: 20113939.
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    81. Harms NJ, Naderi S, Borys D, Bold RJ, Canter RJ. Complex diaphragm reconstruction using dermal collagen matrix after multivisceral resection of retroperitoneal sarcoma. J Thorac Cardiovasc Surg. 2010 Apr; 139(4):1081-3. PMID: 19853863.
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    82. Coates JM, Beal SH, Russo JE, Vanderveen KA, Chen SL, Bold RJ, Canter RJ. Negligible effect of selective preoperative biliary drainage on perioperative resuscitation, morbidity, and mortality in patients undergoing pancreaticoduodenectomy. Arch Surg. 2009 Sep; 144(9):841-7. PMID: 19797109.
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    83. Coates JM, Galante JM, Bold RJ. Cancer therapy beyond apoptosis: autophagy and anoikis as mechanisms of cell death. J Surg Res. 2010 Dec; 164(2):301-8. PMID: 20031162.
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    84. Hausner SH, Abbey CK, Bold RJ, Gagnon MK, Marik J, Marshall JF, Stanecki CE, Sutcliffe JL. Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model. Cancer Res. 2009 Jul 15; 69(14):5843-50. PMID: 19549907.
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    85. Vanderveen KA, Chen SL, Yin D, Cress RD, Bold RJ. Benefit of postoperative adjuvant therapy for pancreatic cancer: A population-based analysis. Cancer. 2009 Jun 01; 115(11):2420-9. PMID: 19301434.
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    86. Kim RH, Bold RJ, Kung HJ. ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer. Autophagy. 2009 May; 5(4):567-8. PMID: 19276647.
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    87. Kim RH, Coates JM, Bowles TL, McNerney GP, Sutcliffe J, Jung JU, Gandour-Edwards R, Chuang FY, Bold RJ, Kung HJ. Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Res. 2009 Jan 15; 69(2):700-8. PMID: 19147587.
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    88. Bowles TL, Kim R, Galante J, Parsons CM, Virudachalam S, Kung HJ, Bold RJ. Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase. Int J Cancer. 2008 Oct 15; 123(8):1950-5. PMID: 18661517.
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    89. Parsons CM, Sutcliffe JL, Bold RJ. Preoperative evaluation of pancreatic adenocarcinoma. J Hepatobiliary Pancreat Surg. 2008; 15(4):429-35. PMID: 18670846.
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    90. Galante JM, Mortenson MM, Bowles TL, Virudachalam S, Bold RJ. ERK/BCL-2 pathway in the resistance of pancreatic cancer to anoikis. J Surg Res. 2009 Mar; 152(1):18-25. PMID: 19062038.
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    91. Vanderveen KA, Ramsamooj R, Bold RJ. A prospective, blinded trial of touch prep analysis versus frozen section for intraoperative evaluation of sentinel lymph nodes in breast cancer. Ann Surg Oncol. 2008 Jul; 15(7):2006-11. PMID: 18481152.
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    92. Martinez SR, Robbins AS, Meyers FJ, Bold RJ, Khatri VP, Goodnight JE. Racial and ethnic differences in treatment and survival among adults with primary extremity soft-tissue sarcoma. Cancer. 2008 Mar 01; 112(5):1162-8. PMID: 18213619.
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    93. Vanderveen K, Bold RJ. Effect of generational composition on the surgical workforce. Arch Surg. 2008 Mar; 143(3):224-6. PMID: 18347267.
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    94. Davies AM, Ruel C, Lara PN, Lau DH, Gumerlock PH, Bold R, Shibata S, Lenz HJ, Schenkein DP, Gandara DR. The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: a California Cancer Consortium Phase I study. J Thorac Oncol. 2008 Jan; 3(1):68-74. PMID: 18166843.
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    95. Mortenson MM, Galante JG, Gilad O, Schlieman MG, Virudachalam S, Kung HJ, Bold RJ. BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer. J Cell Biochem. 2007 Dec 01; 102(5):1171-9. PMID: 17960583.
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    96. Redwine J, Bold RJ. Perioperative care of the patient with hemophilia undergoing urgent appendectomy. Arch Surg. 2007 Sep; 142(9):894-7. PMID: 17875845.
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    97. Vanderveen KA, Paterniti DA, Kravitz RL, Bold RJ. Diffusion of surgical techniques in early stage breast cancer: variables related to adoption and implementation of sentinel lymph node biopsy. Ann Surg Oncol. 2007 May; 14(5):1662-9. PMID: 17285395.
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    98. Wang H, Ryu J, Gandara D, Bold RJ, Urayama S, Tanaka M, Goldberg Z, Follette D, Narayan S, Lau D. A phase II study of paclitaxel, carboplatin, and radiation with or without surgery for esophageal cancer. J Thorac Oncol. 2007 Feb; 2(2):153-7. PMID: 17410032.
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    99. Vanderveen KA, Schneider PD, Khatri VP, Goodnight JE, Bold RJ. Upstaging and improved survival of early breast cancer patients after implementation of sentinel node biopsy for axillary staging. Ann Surg Oncol. 2006 Nov; 13(11):1450-6. PMID: 17009150.
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    100. Cress RD, Yin D, Clarke L, Bold R, Holly EA. Survival among patients with adenocarcinoma of the pancreas: a population-based study (United States). Cancer Causes Control. 2006 May; 17(4):403-9. PMID: 16596292.
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    101. Bold RJ. Re: Rectal cancer surgery in the elderly: a multivariate analysis of outcome risk factors, by Bufalari A, Giustozzi G, Burattini MF, et al. J Surg Oncol. 2006 Mar 01; 93(3):167-8. PMID: 16482591.
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    102. Davies AM, Lara PN, Mack PC, Gumerlock PH, Bold RJ, Gandara DR. Bortezomib-based combinations in the treatment of non-small-cell lung cancer. Clin Lung Cancer. 2005 Oct; 7 Suppl 2:S59-63. PMID: 16250929.
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    103. Lara PN, Bold RJ, Mack PC, Davies AM, Gumerlock PH, Gandara DR. Proteasome inhibition in small-cell lung cancer: preclinical rationale and clinical applications. Clin Lung Cancer. 2005 Oct; 7 Suppl 2:S67-71. PMID: 16250931.
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    104. Galante JM, Bowles TL, Khatri VP, Schneider PD, Goodnight JE, Bold RJ. Experience and attitudes of surgeons toward palliation in cancer. Arch Surg. 2005 Sep; 140(9):873-8; discussion 878-80. PMID: 16172296.
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    105. Mortenson MM, Ho HS, Bold RJ. An analysis of cost and clinical outcome in palliation for advanced pancreatic cancer. Am J Surg. 2005 Sep; 190(3):406-11. PMID: 16105527.
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    106. Mortenson MM, Schlieman MG, Virudachalam S, Lara PN, Gandara DG, Davies AM, Bold RJ. Reduction in BCL-2 levels by 26S proteasome inhibition with bortezomib is associated with induction of apoptosis in small cell lung cancer. Lung Cancer. 2005 Aug; 49(2):163-70. PMID: 16022909.
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    107. Fahy BN, Schlieman MG, Mortenson MM, Virudachalam S, Bold RJ. Targeting BCL-2 overexpression in various human malignancies through NF-kappaB inhibition by the proteasome inhibitor bortezomib. Cancer Chemother Pharmacol. 2005 Jul; 56(1):46-54. PMID: 15791457.
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    108. Bold RJ. A young surgeon's perspective. Arch Surg. 2005 Mar; 140(3):254-7. PMID: 15781788.
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    109. Bold RJ. Standardization of sentinel lymph node biopsy in breast carcinoma. Cancer. 2005 Feb 01; 103(3):444-6. PMID: 15612082.
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    110. Mortenson MM, Schneider PD, Khatri VP, Stevenson TR, Whetzel TP, Sommerhaug EJ, Goodnight JE, Bold RJ. Immediate breast reconstruction after mastectomy increases wound complications: however, initiation of adjuvant chemotherapy is not delayed. Arch Surg. 2004 Sep; 139(9):988-91. PMID: 15381618.
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    111. Mortenson MM, Schlieman MG, Virudachalam S, Bold RJ. Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line. Cancer Chemother Pharmacol. 2004 Oct; 54(4):343-53. PMID: 15197486.
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    112. Bold RJ, Goodnight JE. Hilar cholangiocarcinoma: surgical and endoscopic approaches. Surg Clin North Am. 2004 Apr; 84(2):525-42. PMID: 15062660.
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    113. Fahy BN, Schlieman MG, Virudachalam S, Bold RJ. Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer. J Am Coll Surg. 2004 Apr; 198(4):591-9. PMID: 15051014.
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    114. Lara PN, Davies AM, Mack PC, Mortenson MM, Bold RJ, Gumerlock PH, Gandara DR. Proteasome inhibition with PS-341 (bortezomib) in lung cancer therapy. Semin Oncol. 2004 Feb; 31(1 Suppl 1):40-6. PMID: 14981579.
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    115. Bold R. "Development of the proteasome inhibitor Velcade (Bortezomib)" by Julian Adams, Ph.D., and Michael Kauffman, M.D., Ph.D. Cancer Invest. 2004; 22(2):328-9. PMID: 15199617.
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    116. Schlieman MG, Fahy BN, Ramsamooj R, Beckett L, Bold RJ. Incidence, mechanism and prognostic value of activated AKT in pancreas cancer. Br J Cancer. 2003 Dec 01; 89(11):2110-5. PMID: 14647146.
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    117. Khatri VP, Galante JM, Bold RJ, Schneider PD, Ramsamooj R, Goodnight JE. Dermatofibrosarcoma protuberans: reappraisal of wide local excision and impact of inadequate initial treatment. Ann Surg Oncol. 2003 Nov; 10(9):1118-22. PMID: 14597453.
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    118. Monson K, Litvak DA, Bold RJ. Surgery in the aged population: surgical oncology. Arch Surg. 2003 Oct; 138(10):1061-7. PMID: 14557121.
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    119. Schlieman MG, Ho HS, Bold RJ. Utility of tumor markers in determining resectability of pancreatic cancer. Arch Surg. 2003 Sep; 138(9):951-5; discussion 955-6. PMID: 12963650.
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    120. Fahy BN, Schlieman M, Virudachalam S, Bold RJ. AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2. Br J Cancer. 2003 Jul 21; 89(2):391-7. PMID: 12865934.
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    121. Fahy BN, Schlieman MG, Virudachalam S, Bold RJ. Schedule-dependent molecular effects of the proteasome inhibitor bortezomib and gemcitabine in pancreatic cancer. J Surg Res. 2003 Jul; 113(1):88-95. PMID: 12943815.
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    122. Nawrocki ST, Bruns CJ, Harbison MT, Bold RJ, Gotsch BS, Abbruzzese JL, Elliott P, Adams J, McConkey DJ. Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther. 2002 Dec; 1(14):1243-53. PMID: 12516957.
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    123. Althausen PL, Schneider PD, Bold RJ, Gupta MC, Goodnight JE, Khatri VP. Multimodality management of a giant cell tumor arising in the proximal sacrum: case report. Spine (Phila Pa 1976). 2002 Aug 01; 27(15):E361-5. PMID: 12163737.
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    124. Fahy BN, Bold RJ, Beckett L, Schneider PD. Modern parathyroid surgery: a cost-benefit analysis of localizing strategies. Arch Surg. 2002 Aug; 137(8):917-22; discussion 922-3. PMID: 12146990.
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    125. Stein M, Schneider PD, Ho HS, Eckert R, Urayama S, Bold RJ. Percutaneous transhepatic portography with intravascular ultrasonography for evaluation of venous involvement of hepatobiliary and pancreatic tumors. J Vasc Interv Radiol. 2002 Aug; 13(8):805-14. PMID: 12171984.
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    126. Losanoff JE, Richman BW, Jones JW. Tamponade of presacral venous hemorrhage. Dis Colon Rectum. 2002 Jul; 45(7):981-2; author reply 982-3. PMID: 12130893.
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    127. Bold RJ. Re: Accuracy of sentinel lymph node biopsy for patients with T2 and T3 breast cancers. Am Surg. 2002 May; 68(5):500; author reply 500. PMID: 12013299.
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    128. Fahy BN, Frey CF, Ho HS, Beckett L, Bold RJ. Morbidity, mortality, and technical factors of distal pancreatectomy. Am J Surg. 2002 Mar; 183(3):237-41. PMID: 11943118.
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    129. Schlieman M, Stein M, McVicar J, Bold R. Hepatic artery aneurysm within focal nodular hyperplasia. J Hepatol. 2002 Feb; 36(2):302. PMID: 11830345.
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    130. Bold RJ. Surgical management of breast cancer: today and tomorrow. Cancer Biother Radiopharm. 2002 Feb; 17(1):1-9. PMID: 11915165.
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    131. Braley SC, Schneider PD, Bold RJ, Goodnight JE, Khatri VP. Controlled tamponade of severe presacral venous hemorrhage: use of a breast implant sizer. Dis Colon Rectum. 2002 Jan; 45(1):140-2. PMID: 11786781.
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    132. Mortenson M, Bold RJ. Symptomatic pancreatic polypeptide-secreting tumor of the distal pancreas (PPoma). Int J Gastrointest Cancer. 2002; 32(2-3):153-6. PMID: 12794252.
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    133. Bold RJ, Fahy BN. Practice patterns in sentinel lymph node biopsy. J Am Coll Surg. 2001 Oct; 193(4):466-7. PMID: 11584980.
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    134. Bold RJ, Schlieman M, Fahy BN. Sentinel lymph node biopsy for breast cancer. Cancer Biother Radiopharm. 2001 Oct; 16(5):347-57. PMID: 11776752.
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    135. Bold RJ, Virudachalam S, McConkey DJ. BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines. Cancer. 2001 Sep 01; 92(5):1122-9. PMID: 11571724.
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    136. Bold RJ, Virudachalam S, McConkey DJ. Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome. J Surg Res. 2001 Sep; 100(1):11-7. PMID: 11516199.
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    137. Fahy BN, Bold RJ, Schneider PD, Khatri V, Goodnight JE. Cost-benefit analysis of biopsy methods for suspicious mammographic lesions; discussion 994-5. Arch Surg. 2001 Sep; 136(9):990-4. PMID: 11529819.
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    138. Bold RJ, Schneider PD, Khatri VP, Goodnight JE. Resident experience and opinions about physician-assisted death for cancer patients. Arch Surg. 2001 Jan; 136(1):60-4. PMID: 11146779.
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    139. Nguyen NT, Mayer KL, Bold RJ, Larson M, Foster S, Ho HS, Wolfe BM. Laparoscopic suturing evaluation among surgical residents. J Surg Res. 2000 Sep; 93(1):133-6. PMID: 10945954.
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    140. Neuhaus A, Bold RJ. Images in surgery. Small bowel stromal cell tumor. Am J Surg. 2000 Apr; 179(4):252. PMID: 10875978.
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    141. Bold RJ, Schneider PD, Goodnight JE. Sentinel node biopsy in breast cancer. Ann Surg. 2000 Jan; 231(1):148-9. PMID: 10636115.
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    142. Bold RJ, Charnsangavej C, Cleary KR, Jennings M, Madray A, Leach SD, Abbruzzese JL, Pisters PW, Lee JE, Evans DB. Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. J Gastrointest Surg. 1999 May-Jun; 3(3):233-43. PMID: 10481116.
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    143. Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Bucana CD, Cleary KR, Hallin PA, Chiao PJ, Abbruzzese JL, Evans DB. Prognostic factors in resectable pancreatic cancer: p53 and bcl-2. J Gastrointest Surg. 1999 May-Jun; 3(3):263-77. PMID: 10481119.
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    144. Bold RJ, Ota DM, Ajani JA, Mansfield PF. Peritoneal and serum tumor markers predict recurrence and survival of patients with resectable gastric cancer. Gastric Cancer. 1999 May; 2(1):1-7. PMID: 11957063.
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    145. Bold RJ, Chandra J, McConkey DJ. Gemcitabine-induced programmed cell death (apoptosis) of human pancreatic carcinoma is determined by Bcl-2 content. Ann Surg Oncol. 1999 Apr-May; 6(3):279-85. PMID: 10340887.
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    146. Pearlstone DB, Pisters PW, Bold RJ, Feig BW, Hunt KK, Yasko AW, Patel S, Pollack A, Benjamin RS, Pollock RE. Patterns of recurrence in extremity liposarcoma: implications for staging and follow-up. Cancer. 1999 Jan 01; 85(1):85-92. PMID: 9921978.
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    147. Bouvet M, Bold RJ, Lee J, Evans DB, Abbruzzese JL, Chiao PJ, McConkey DJ, Chandra J, Chada S, Fang B, Roth JA. Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]. Ann Surg Oncol. 1998 Dec; 5(8):681-8. PMID: 9869513.
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    148. Bold RJ, Ishizuka J, Yao CZ, Townsend CM, Thompson JC. Bombesin stimulates in vitro growth of human breast cancer independent of estrogen receptors status. Anticancer Res. 1998 Nov-Dec; 18(6A):4051-6. PMID: 9891444.
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    149. Fahy B, Bold RJ. Epidemiology and molecular genetics of colorectal cancer. Surg Oncol. 1998 Nov-Dec; 7(3-4):115-23. PMID: 10677163.
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    150. Bold RJ, Winchester DJ, Madary AR, Gregurich MA, Mansfield PF. Prospective, randomized trial of Doppler-assisted subclavian vein catheterization. Arch Surg. 1998 Oct; 133(10):1089-93. PMID: 9790206.
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    151. Bold RJ, Mansfield PF, Berger DH, Pollock RE, Singletary SE, Ames FC, Balch CM, Hohn DC, Ross MI. Prospective, randomized, double-blind study of prophylactic antibiotics in axillary lymph node dissection. Am J Surg. 1998 Sep; 176(3):239-43. PMID: 9776150.
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    152. Evans DB, Pisters PW, Lee JE, Bold RJ, Charnsangavej C, Janjan NA, Wolff RA, Abbruzzese JL. Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas. J Hepatobiliary Pancreat Surg. 1998; 5(3):242-50. PMID: 9880770.
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    153. Bold RJ, Kim HJ, Ishizuka J, Townsend CM, Thompson JC. A human gastric cancer cell line possesses a functional receptor for gastrin-releasing peptide. Cancer Invest. 1998; 16(1):12-7. PMID: 9474246.
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    154. Bold RJ, Termuhlen PM, McConkey DJ. Apoptosis, cancer and cancer therapy. Surg Oncol. 1997 Nov; 6(3):133-42. PMID: 9576629.
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    155. Bold RJ, Kroll SS, Baldwin BJ, Ross MI, Singletary SE. Local rotational flaps for breast conservation therapy as an alternative to mastectomy. Ann Surg Oncol. 1997 Oct-Nov; 4(7):540-4. PMID: 9367018.
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    156. Hirai A, Bold RJ, Ishizuka J, Hirai M, Townsend CM, Thompson JC. Hyperphosphorylation of retinoblastoma protein and stimulation of growth by okadaic acid in human pancreatic cancer. Dig Dis Sci. 1996 Oct; 41(10):1975-80. PMID: 8888710.
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    157. Organ CH, Bold RJ. Surgery. JAMA. 1996 Jun 19; 275(23):1855-7. PMID: 8642750.
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    158. Bold RJ, Ishizuka J, Townsend CM, Thompson JC. All-trans-retinoic acid inhibits growth of human pancreatic cancer cell lines. Pancreas. 1996 Mar; 12(2):189-95. PMID: 8720668.
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    159. Yao CZ, Ishizuka J, Bold RJ, Sperling HE, Townsend CM, Thompson JC. Human monoclonal antibody against colon cancer. Cancer Invest. 1996; 14(3):211-7. PMID: 8630681.
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    160. Bold RJ, Ishizuka J, Townsend CM. Progress toward hormonal therapy of gastrointestinal cancer. Ann Surg. 1996 Jan; 223(1):4-11. PMID: 8554417.
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    161. Bold RJ, Ishizuka J, Townsend CM, Thompson JC. Secretin potentiates cholecystokinin-stimulated amylase release by AR4-2J cells via a stimulation of phospholipase C. J Cell Physiol. 1995 Oct; 165(1):172-6. PMID: 7559798.
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    162. Yao CZ, Bold RJ, Ishizuka J, Townsend CM, Thompson JC. Growth of mouse hepatocytes is stimulated by gastrin. J Cell Physiol. 1995 Jun; 163(3):532-7. PMID: 7775596.
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    163. Bold RJ, Ishizuka J, Rajaraman S, Perez-Polo JR, Townsend CM, Thompson JC. Nerve growth factor as a mitogen for a pancreatic carcinoid cell line. J Neurochem. 1995 Jun; 64(6):2622-8. PMID: 7760042.
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    164. Ishizuka J, Bold RJ, Townsend CM, Thompson JC. Role of calcium in the regulation of ornithine decarboxylase enzyme activity in mouse colon cancer cells. Cancer Invest. 1995; 13(2):181-7. PMID: 7874572.
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    165. Bold RJ, Lowry PS, Ishizuka J, Battey JF, Townsend CM, Thompson JC. Bombesin stimulates the in vitro growth of a human gastric cancer cell line. J Cell Physiol. 1994 Dec; 161(3):519-25. PMID: 7962132.
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    166. Bold RJ, Alpard S, Ishizuka J, Townsend CM, Thompson JC. Growth-regulatory effect of gastrin on human colon cancer cell lines is determined by protein kinase a isoform content. Regul Pept. 1994 Aug 31; 53(1):61-70. PMID: 7800859.
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    167. Bold RJ, Ishizuka J, Townsend CM, Thompson JC. Gastrin stimulates growth of human colon cancer cells via a receptor other than CCK-A or CCK-B. Biochem Biophys Res Commun. 1994 Aug 15; 202(3):1222-6. PMID: 8060296.
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    168. Evers BM, Bold RJ, Ehrenfried JA, Li J, Townsend CM, Klimpel GR. Characterization of functional neurotensin receptors on human lymphocytes. Surgery. 1994 Aug; 116(2):134-9; discussion 139-40. PMID: 8047978.
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    169. Yao CZ, Ishizuka J, Bold RJ, Townsend CM, Thompson JC. Cytocidal effect of high energy shock wave on tumour cells enhanced with larger dose and multiple exposures. Surg Oncol. 1994 Aug; 3(4):229-35. PMID: 7834114.
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    170. Bold RJ, Warren RE, Ishizuka J, Cho-Chung YS, Townsend CM, Thompson JC. Experimental gene therapy of human colon cancer. Surgery. 1994 Aug; 116(2):189-95; discussion 195-6. PMID: 8047985.
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    171. Ishizuka J, Townsend CM, Bold RJ, Martinez J, Rodriguez M, Thompson JC. Effects of gastrin on 3',5'-cyclic adenosine monophosphate, intracellular calcium, and phosphatidylinositol hydrolysis in human colon cancer cells. Cancer Res. 1994 Apr 15; 54(8):2129-35. PMID: 8174118.
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    172. Ishizuka J, Bold RJ, Townsend CM, Thompson JC. In vitro relationship between magnesium and insulin secretion. Magnes Res. 1994 Mar; 7(1):17-22. PMID: 8054257.
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    173. Townsend CM, Bold RJ, Ishizuka J. Gastrointestinal hormones and cell proliferation. Surg Today. 1994; 24(9):772-7. PMID: 7865952.
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    174. Bold RJ, Ishizuka J, Townsend CM, Thompson JC. Biomolecular advances in gastrointestinal hormones. Arch Surg. 1993 Nov; 128(11):1268-73. PMID: 8239990.
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    175. Hirai M, Ishizuka J, Hirai A, Bold RJ, Townsend CM, Thompson JC. Bombesin stimulates intracellular Ca2+ mobilization but not proliferation on human colon cancer cells. Life Sci. 1993; 53(24):1859-65. PMID: 8246684.
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    176. Bold RJ, Hannink M, Donoghue DJ. Functions of the mos oncogene family and associated gene products. Cancer Surv. 1986; 5(2):243-55. PMID: 2946405.
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    177. Bold RJ, Donoghue DJ. Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors. Mol Cell Biol. 1985 Nov; 5(11):3131-8. PMID: 3018503.
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