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Helen K Chew

Title(s)Professor, Hematology and Oncology
SchoolUniversity of California, Davis
Phone916-734-3772
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gralow JR, Barlow WE, Paterson AHG, Miao JL, Lew DL, Stopeck AT, Hayes DF, Hershman DL, Schubert MM, Clemons M, Van Poznak CH, Dees EC, Ingle JN, Falkson CI, Elias AD, Messino MJ, Margolis JH, Dakhil SR, Chew HK, Dammann KZ, Abrams JS, Livingston RB, Hortobagyi GN. Phase III randomized trial of bisphosphonates as adjuvant therapy in breast cancer: S0307. J Natl Cancer Inst. 2019 Oct 31. PMID: 31693129.
      View in: PubMed
    2. Hausner SH, Bold RJ, Cheuy LY, Chew HK, Daly ME, Davis RA, Foster CC, Kim EJ, Sutcliffe JL. Preclinical Development and First-in-Human Imaging of the Integrin avß6 with [18F]avß6-Binding Peptide in Metastatic Carcinoma. Clin Cancer Res. 2019 Feb 15; 25(4):1206-1215. PMID: 30401687.
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    3. Parikh M, Galkin M, Brunson A, Keegan T, Chew HK. Breast cancer-specific survival in patients with HER2-positive, node-negative T1a and T1b breast cancer. Cancer Treat Res Commun. 2018; 16:38-44. PMID: 31299001.
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    4. Keegan THM, Kushi LH, Li Q, Brunson A, Chawla X, Chew HK, Malogolowkin M, Wun T. Cardiovascular disease incidence in adolescent and young adult cancer survivors: a retrospective cohort study. J Cancer Surviv. 2018 06; 12(3):388-397. PMID: 29427203.
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    5. Yang D, Quan W, Wu J, Ji X, Dai Y, Xiao W, Chew H, Sun Z, Li D. The value of red blood cell distribution width in diagnosis of patients with colorectal cancer. Clin Chim Acta. 2018 Apr; 479:98-102. PMID: 29407693.
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    6. Hortobagyi GN, Van Poznak C, Harker WG, Gradishar WJ, Chew H, Dakhil SR, Haley BB, Sauter N, Mohanlal R, Zheng M, Lipton A. Continued Treatment Effect of Zoledronic Acid Dosing Every 12 vs 4 Weeks in Women With Breast Cancer Metastatic to Bone: The OPTIMIZE-2 Randomized Clinical Trial. JAMA Oncol. 2017 Jul 01; 3(7):906-912. PMID: 28125763.
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    7. Somlo G, Frankel PH, Arun BK, Ma CX, Garcia AA, Cigler T, Cream LV, Harvey HA, Sparano JA, Nanda R, Chew HK, Moynihan TJ, Vahdat LT, Goetz MP, Beumer JH, Hurria A, Mortimer J, Piekarz R, Sand S, Herzog J, Van Tongeren LR, Ferry-Galow KV, Chen AP, Ruel C, Newman EM, Gandara DR, Weitzel JN. Efficacy of the PARP Inhibitor Veliparib with Carboplatin or as a Single Agent in Patients with Germline BRCA1- or BRCA2-Associated Metastatic Breast Cancer: California Cancer Consortium Trial NCT01149083. Clin Cancer Res. 2017 Aug 01; 23(15):4066-4076. PMID: 28356425.
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    8. Cress RD, Chen YS, Morris CR, Chew H, Kizer KW. Underutilization of gene expression profiling for early-stage breast cancer in California. Cancer Causes Control. 2016 06; 27(6):721-7. PMID: 27097910.
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    9. Gilbert J, Chew H, Dewey C, Horn L. Medical education: perils and progress in educating and assessing a new generation of learners. Am Soc Clin Oncol Educ Book. 2015; 33-9. PMID: 25993139.
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    10. Budd GT, Barlow WE, Moore HC, Hobday TJ, Stewart JA, Isaacs C, Salim M, Cho JK, Rinn KJ, Albain KS, Chew HK, Burton GV, Moore TD, Srkalovic G, McGregor BA, Flaherty LE, Livingston RB, Lew DL, Gralow JR, Hortobagyi GN. SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol. 2015 Jan 01; 33(1):58-64. PMID: 25422488.
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    11. Burstein HJ, Cirrincione CT, Barry WT, Chew HK, Tolaney SM, Lake DE, Ma C, Blackwell KL, Winer EP, Hudis CA. Endocrine therapy with or without inhibition of epidermal growth factor receptor and human epidermal growth factor receptor 2: a randomized, double-blind, placebo-controlled phase III trial of fulvestrant with or without lapatinib for postmenopausal women with hormone receptor-positive advanced breast cancer-CALGB 40302 (Alliance). J Clin Oncol. 2014 Dec 10; 32(35):3959-66. PMID: 25348000.
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    12. Shanafelt TD, Raymond M, Horn L, Moynihan T, Collichio F, Chew H, Kosty MP, Satele D, Sloan J, Gradishar WJ. Oncology fellows’ career plans, expectations, and well-being: do fellows know what they are getting into? J Clin Oncol. 2014 Sep 20; 32(27):2991-7. PMID: 25049326.
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    13. Mahajan A, Wun T, Chew H, White RH. Lymphoma and venous thromboembolism: influence on mortality. Thromb Res. 2014 May; 133 Suppl 2:S23-8. PMID: 24862141.
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    14. Shanafelt TD, Raymond M, Kosty M, Satele D, Horn L, Pippen J, Chu Q, Chew H, Clark WB, Hanley AE, Sloan J, Gradishar WJ. Satisfaction with work-life balance and the career and retirement plans of US oncologists. J Clin Oncol. 2014 Apr 10; 32(11):1127-35. PMID: 24616305.
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    15. Chew HK, Schwartzberg L, Badarinath S, Rubin P, Shumaker G, Daugherty J, DeSilvio M, Mahoney J. Phase II study of lapatinib in combination with vinorelbine, as first or second-line therapy in women with HER2 overexpressing metastatic breast cancer. Springerplus. 2014; 3:108. PMID: 26034656.
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    16. Shanafelt TD, Gradishar WJ, Kosty M, Satele D, Chew H, Horn L, Clark B, Hanley AE, Chu Q, Pippen J, Sloan J, Raymond M. Burnout and career satisfaction among US oncologists. J Clin Oncol. 2014 Mar 01; 32(7):678-86. PMID: 24470006.
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    17. Mayadev J, Daly M, Chen A, Bold R, Chew H. The potential role of radiation therapy to the primary site of disease in stage IV breast cancer presenting with synchronous metastasis. Clin Breast Cancer. 2014 Feb; 14(1):10-2. PMID: 24183416.
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    18. Ho C, Davies AM, Sangha RS, Lau D, Lara P, Chew HK, Beckett L, Mack PC, Riess JW, Gandara DR. Phase I/II trial of pemetrexed plus nab-paclitaxel in advanced solid tumor patients with emphasis on non-small cell lung cancer. Invest New Drugs. 2013 Dec; 31(6):1587-91. PMID: 24013936.
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    19. Barnhard S, Pai A, Chew HK, Song JY. Richter's syndrome with aberrant CD2 and CD4 expression. J Clin Oncol. 2012 Sep 10; 30(26):e243-5. PMID: 22649134.
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    20. Schott AF, Barlow WE, Albain KS, Chew HK, Wade JL, Lanier KS, Lew DL, Hayes DF, Gralow JR, Livingston RB, Hortobagyi GN. Phase II trial of simple oral therapy with capecitabine and cyclophosphamide in patients with metastatic breast cancer: SWOG S0430. Oncologist. 2012; 17(2):179-87. PMID: 22267853.
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    21. Chew HK, Somlo G, Mack PC, Gitlitz B, Gandour-Edwards R, Christensen S, Linden H, Solis LJ, Yang X, Davies AM. Phase I study of continuous and intermittent schedules of lapatinib in combination with vinorelbine in solid tumors. Ann Oncol. 2012 Apr; 23(4):1023-9. PMID: 21778300.
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    22. de Leoz ML, Young LJ, An HJ, Kronewitter SR, Kim J, Miyamoto S, Borowsky AD, Chew HK, Lebrilla CB. High-mannose glycans are elevated during breast cancer progression. Mol Cell Proteomics. 2011 Jan; 10(1):M110.002717. PMID: 21097542.
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    23. Sandhu R, Pan CX, Wun T, Harvey D, Zhou H, White RH, Chew HK. The incidence of venous thromboembolism and its effect on survival among patients with primary bladder cancer. Cancer. 2010 Jun 01; 116(11):2596-603. PMID: 20336780.
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    24. Lo SS, Mumby PB, Norton J, Rychlik K, Smerage J, Kash J, Chew HK, Gaynor ER, Hayes DF, Epstein A, Albain KS. Prospective multicenter study of the impact of the 21-gene recurrence score assay on medical oncologist and patient adjuvant breast cancer treatment selection. J Clin Oncol. 2010 Apr 01; 28(10):1671-6. PMID: 20065191.
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    25. Chew HK, Doroshow JH, Frankel P, Margolin KA, Somlo G, Lenz HJ, Gordon M, Zhang W, Yang D, Russell C, Spicer D, Synold T, Bayer R, Hantel A, Stiff PJ, Tetef ML, Gandara DR, Albain KS. Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer. J Clin Oncol. 2009 May 01; 27(13):2163-9. PMID: 19307510.
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    26. Ku GH, White RH, Chew HK, Harvey DJ, Zhou H, Wun T. Venous thromboembolism in patients with acute leukemia: incidence, risk factors, and effect on survival. Blood. 2009 Apr 23; 113(17):3911-7. PMID: 19088376.
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    27. Barkauskas DA, An HJ, Kronewitter SR, de Leoz ML, Chew HK, de Vere White RW, Leiserowitz GS, Miyamoto S, Lebrilla CB, Rocke DM. Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data. Bioinformatics. 2009 Jan 15; 25(2):251-7. PMID: 19073586.
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    28. Chew HK, Barlow WE, Albain K, Lew D, Gown A, Hayes DF, Gralow J, Hortobagyi GN, Livingston R. A phase II study of imatinib mesylate and capecitabine in metastatic breast cancer: Southwest Oncology Group Study 0338. Clin Breast Cancer. 2008 Dec; 8(6):511-5. PMID: 19073506.
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    29. Rodriguez AO, Chew H, Cress R, Xing G, McElvy S, Danielsen B, Smith L. Evidence of poorer survival in pregnancy-associated breast cancer. Obstet Gynecol. 2008 Jul; 112(1):71-8. PMID: 18591310.
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    30. Xiao GG, Zhou BS, Somlo G, Portnow J, Juhasz A, Un F, Chew H, Gandara D, Yen Y. Identification of F-box/LLR-repeated protein 17 as potential useful biomarker for breast cancer therapy. Cancer Genomics Proteomics. 2008 May-Aug; 5(3-4):151-60. PMID: 18820369.
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    31. Chew HK. 25th Chemotherapy Foundation Symposium. Innovative Cancer Therapy for Tomorrow. 6-10 November 2007, New York, NY, USA. IDrugs. 2008 Feb; 11(2):90-3. PMID: 18240090.
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    32. Chew HK, Davies AM, Wun T, Harvey D, Zhou H, White RH. The incidence of venous thromboembolism among patients with primary lung cancer. J Thromb Haemost. 2008 Apr; 6(4):601-8. PMID: 18208538.
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    33. Jeng YM, Cai-Ng S, Li A, Furuta S, Chew H, Chen PL, Lee EY, Lee WH. Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation. Oncogene. 2007 Sep 13; 26(42):6160-6. PMID: 17420720.
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    34. Rodriguez AO, Wun T, Chew H, Zhou H, Harvey D, White RH. Venous thromboembolism in ovarian cancer. Gynecol Oncol. 2007 Jun; 105(3):784-90. PMID: 17408726.
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    35. Moore HC, Green SJ, Gralow JR, Bearman SI, Lew D, Barlow WE, Hudis C, Wolff AC, Ingle JN, Chew HK, Elias AD, Livingston RB, Martino S. Intensive dose-dense compared with high-dose adjuvant chemotherapy for high-risk operable breast cancer: Southwest Oncology Group/Intergroup study 9623. J Clin Oncol. 2007 May 01; 25(13):1677-82. PMID: 17404368.
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    36. Semrad TJ, O'Donnell R, Wun T, Chew H, Harvey D, Zhou H, White RH. Epidemiology of venous thromboembolism in 9489 patients with malignant glioma. J Neurosurg. 2007 Apr; 106(4):601-8. PMID: 17432710.
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    37. Chew HK, Wun T, Harvey DJ, Zhou H, White RH. Incidence of venous thromboembolism and the impact on survival in breast cancer patients. J Clin Oncol. 2007 Jan 01; 25(1):70-6. PMID: 17194906.
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    38. White RH, Chew H, Wun T. Targeting patients for anticoagulant prophylaxis trials in patients with cancer: who is at highest risk? Thromb Res. 2007; 120 Suppl 2:S29-40. PMID: 18023711.
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    39. Kirmiz C, Li B, An HJ, Clowers BH, Chew HK, Lam KS, Ferrige A, Alecio R, Borowsky AD, Sulaimon S, Lebrilla CB, Miyamoto S. A serum glycomics approach to breast cancer biomarkers. Mol Cell Proteomics. 2007 Jan; 6(1):43-55. PMID: 16847285.
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    40. Juhasz A, Vassilakos A, Chew HK, Gandara D, Yen Y. Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment. Oncol Rep. 2006 May; 15(5):1299-304. PMID: 16596201.
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    41. Alcalay A, Wun T, Khatri V, Chew HK, Harvey D, Zhou H, White RH. Venous thromboembolism in patients with colorectal cancer: incidence and effect on survival. J Clin Oncol. 2006 Mar 01; 24(7):1112-8. PMID: 16505431.
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    42. Chew HK, Wun T, Harvey D, Zhou H, White RH. Incidence of venous thromboembolism and its effect on survival among patients with common cancers. Arch Intern Med. 2006 Feb 27; 166(4):458-64. PMID: 16505267.
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    43. Mohsin SK, Allred DC, Osborne CK, Cruz A, Otto P, Chew H, Clark GM, Elledge RM. Morphologic and immunophenotypic markers as surrogate endpoints of tamoxifen effect for prevention of breast cancer. Breast Cancer Res Treat. 2005 Dec; 94(3):205-11. PMID: 16267611.
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    44. Richman CM, Denardo SJ, O'Donnell RT, Yuan A, Shen S, Goldstein DS, Tuscano JM, Wun T, Chew HK, Lara PN, Kukis DL, Natarajan A, Meares CF, Lamborn KR, DeNardo GL. High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody. Clin Cancer Res. 2005 Aug 15; 11(16):5920-7. PMID: 16115934.
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    45. White RH, Chew HK, Zhou H, Parikh-Patel A, Harris D, Harvey D, Wun T. Incidence of venous thromboembolism in the year before the diagnosis of cancer in 528,693 adults. Arch Intern Med. 2005 Aug 8-22; 165(15):1782-7. PMID: 16087828.
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    46. Martel CL, Li Y, Beckett L, Chew H, Christensen S, Davies A, Lam KS, Lau DH, Meyers FJ, O'donnell RT, Richman C, Scudder S, Tanaka M, Tuscano J, Welborn J, Wun T, Gandara DR, Lara PN. An evaluation of barriers to accrual in the era of legislation requiring insurance coverage of cancer clinical trial costs in California. Cancer J. 2004 Sep-Oct; 10(5):294-300. PMID: 15530258.
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    47. Cabart P, Chew HK, Murphy S. BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II. Oncogene. 2004 Jul 08; 23(31):5316-29. PMID: 15107825.
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    48. Chew HK. Medical management of breast cancer: today and tomorrow. Cancer Biother Radiopharm. 2002 Apr; 17(2):137-49. PMID: 12030108.
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    49. Chew HK. Adjuvant therapy for breast cancer: who should get what? West J Med. 2001 Apr; 174(4):284-7. PMID: 11290691.
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    50. Chew HK. Genetic evaluation of cancer: the importance of family history. Tex Med. 2001 Feb; 97(2):40-5. PMID: 11233057.
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    51. Chen Y, Lee WH, Chew HK. Emerging roles of BRCA1 in transcriptional regulation and DNA repair. J Cell Physiol. 1999 Dec; 181(3):385-92. PMID: 10528224.
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    52. Lee WH, Chew HK, Farmer AA, Chen PL. Biological functions of the BRCA1 protein. Breast Dis. 1998 Apr; 10(1-2):11-22. PMID: 15687545.
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