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A novel lipophilic amiloride derivative efficiently kills chemoresistant breast cancer cells. Sci Rep. 2024 08 31; 14(1):20263.
Hu M, Liu R, Castro N, Loza Sanchez L, Rueankham L, Learn JA, Huang R, Lam KS, Carraway KL. PMID: 39217266; PMCID: PMC11365969.
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Versatility and stability of melamine foam-based biosensors (f-ELISA) using antibodies, nanobodies, and peptides as sensing probes. Talanta. 2024 Nov 01; 279:126634.
Pan B, He Q, Yu X, De Choch D, Lam KS, Hammock BD, Sun G. PMID: 39121553.
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PubMed Mentions: Fields:
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Topical treatment of tyrosine kinase 2 inhibitor through borneol-embedded hydrogel: Evaluation for preventive, therapeutic, and Recurrent management of psoriasis. Bioact Mater. 2024 Nov; 41:83-95.
Lai Y, Wu X, Jiang Z, Fang Y, Liu X, Hong D, Jiang Y, Tan G, Tang S, Lu S, Wei D, Hwang ST, Lam KS, Wang L, Huang Y, Shi Z. PMID: 39104775; PMCID: PMC11298611.
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Structure-Activity Relationship Study Identifies a Novel Lipophilic Amiloride Derivative that Efficiently Kills Chemoresistant Breast Cancer Cells. bioRxiv. 2024 Jul 02.
Hu M, Liu R, Castro N, Sanchez LL, Learn J, Huang R, Lam KS, Carraway KL. PMID: 37292759; PMCID: PMC10245970.
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A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. Bioact Mater. 2023 Oct; 28:467-479.
Hao D, Lin J, Liu R, Pivetti C, Yamashiro K, Schutzman LM, Sageshima J, Kwong M, Bahatyrevich N, Farmer DL, Humphries MD, Lam KS, Panitch A, Wang A. PMID: 37408799; PMCID: PMC10318457.
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Discovery of Peptidic Ligands against the SARS-CoV-2 Spike Protein and Their Use in the Development of a Highly Sensitive Personal Use Colorimetric COVID-19 Biosensor. ACS Sens. 2023 06 23; 8(6):2159-2168.
Yu X, Pan B, Zhao C, Shorty D, Solano LN, Sun G, Liu R, Lam KS. PMID: 37253267; PMCID: PMC10255569.
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PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Protocol for vision transformer-based evaluation of drug potency using images processed by an optimized Sobel operator. STAR Protoc. 2023 May 01; 4(2):102259.
Wang Y, Zhang W, Wu Y, Qu C, Hu H, Lee T, Lin S, Zhang J, Lam KS, Wang A. PMID: 37133992; PMCID: PMC10176075.
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Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. Front Pharmacol. 2023; 14:1125209.
Song H, Gao K, Hao D, Li A, Liu R, Anggito B, Yin B, Jin Q, Dartora V, Lam KS, Smith LR, Panitch A, Zhou J, Farmer DL, Wang A. PMID: 36937891; PMCID: PMC10014525.
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PubMed Mentions:
2
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SIC50: Determining drug inhibitory concentrations using a vision transformer and an optimized Sobel operator. Patterns (N Y). 2023 Feb 10; 4(2):100686.
Wang Y, Zhang W, Yip H, Qu C, Hu H, Chen X, Lee T, Yang X, Yang B, Kumar P, Lee SY, Casimiro JJ, Zhang J, Wang A, Lam KS. PMID: 36873901; PMCID: PMC9982297.
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Site-Specific Albumin-Selective Ligation to Human Serum Albumin under Physiological Conditions. Bioconjug Chem. 2022 12 21; 33(12):2332-2340.
Yu X, Ruan M, Wang Y, Nguyen A, Xiao W, Ajena Y, Solano LN, Liu R, Lam KS. PMID: 36350013; PMCID: PMC9782315.
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Translation:
HumansCells
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Phototherapy with Cancer-Specific Nanoporphyrin Potentiates Immunotherapy in Bladder Cancer. Clin Cancer Res. 2022 11 01; 28(21):4820-4831.
Zhu Z, Ma AH, Zhang H, Lin TY, Xue X, Farrukh H, Zhu S, Shi W, Yuan R, Cao Z, Chittepu VCSR, Prabhala R, Li Y, Lam KS, Pan CX. PMID: 35921526; PMCID: PMC9633390.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Bioinspired Screening of Anti-Adhesion Peptides against Blood Proteins for Intravenous Delivery of Nanomaterials. Nano Lett. 2022 10 26; 22(20):8076-8085.
Li YJ, Zhang L, Yang PP, Zhang K, Gong XF, Hou DY, Cao H, Wu XC, Liu R, Lam KS, Wang L. PMID: 36135098.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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MAIA, Fc receptor-like 3, supersedes JUNO as IZUMO1 receptor during human fertilization. Sci Adv. 2022 Sep 09; 8(36):eabn0047.
Vondrakova J, Frolikova M, Ded L, Cerny J, Postlerova P, Palenikova V, Simonik O, Nahacka Z, Basus K, Valaskova E, Machan R, Pacey A, Holubcova Z, Koubek P, Ezrova Z, Park S, Liu R, Partha R, Clark N, Neuzil J, Ikawa M, Erickson K, Lam KS, Moore H, Komrskova K. PMID: 36070373; PMCID: PMC9451160.
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PubMed Mentions:
7 Fields:
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Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect. Biomaterials. 2022 10; 289:121769.
Jing D, Jiang N, Wang F, Mao C, Han S, Ho PY, Xiao W, Li Y, Li JJ, Zhang L, Lam KS. PMID: 36084485; PMCID: PMC10021813.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. Theranostics. 2022; 12(13):6021-6037.
Hao D, Lu L, Song H, Duan Y, Chen J, Carney R, Li JJ, Zhou P, Nolta J, Lam KS, Leach JK, Farmer DL, Panitch A, Wang A. PMID: 35966577; PMCID: PMC9373818.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Programmable Bispecific Nano-immunoengager That Captures T Cells and Reprograms Tumor Microenvironment. Nano Lett. 2022 09 14; 22(17):6866-6876.
Zhang L, Bo R, Wu Y, Li L, Zhu Z, Ma AH, Xiao W, Huang Y, Rojalin T, Yin X, Mao C, Wang F, Wang Y, Zhang H, Low KE, Lee K, Ajena Y, Jing D, Zhang D, Baehr CM, Liu R, Wang L, Li Y, Lam KS. PMID: 35926215; PMCID: PMC9479133.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Discovery and Characterization of a Potent Antifungal Peptide through One-Bead, One-Compound Combinatorial Library Screening. ACS Infect Dis. 2022 07 08; 8(7):1291-1302.
Bansal S, Vu K, Liu R, Ajena Y, Xiao W, Menon SM, Bennett A, Gelli A, Lam KS. PMID: 35700987.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. Bioact Mater. 2023 Feb; 20:179-193.
Hao D, Liu R, Fernandez TG, Pivetti C, Jackson JE, Kulubya ES, Jiang HJ, Ju HY, Liu WL, Panitch A, Lam KS, Leach JK, Farmer DL, Wang A. PMID: 35663336; PMCID: PMC9160290.
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PubMed Mentions:
5
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Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior. Cells. 2022 04 21; 11(9).
Kumar VE, Nambiar R, De Souza C, Nguyen A, Chien J, Lam KS. PMID: 35563709; PMCID: PMC9102449.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511.
Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent. RSC Adv. 2022 Mar 08; 12(13):7742-7756.
Zhou J, Meli VS, Yu-Tin Chen E, Kapre R, Nagalla R, Xiao W, Borowsky AD, Lam KS, Liu WF, Louie AY. PMID: 35424752; PMCID: PMC8982161.
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PubMed Mentions:
7
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Selectin-targeting glycosaminoglycan-peptide conjugate limits neutrophil-mediated cardiac reperfusion injury. Cardiovasc Res. 2022 01 07; 118(1):267-281.
Dehghani T, Thai PN, Sodhi H, Ren L, Sirish P, Nader CE, Timofeyev V, Overton JL, Li X, Lam KS, Chiamvimonvat N, Panitch A. PMID: 33125066; PMCID: PMC8932156.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing. Bioact Mater. 2022 Apr; 10:460-473.
He S, Walimbe T, Chen H, Gao K, Kumar P, Wei Y, Hao D, Liu R, Farmer DL, Lam KS, Zhou J, Panitch A, Wang A. PMID: 34901560; PMCID: PMC8636679.
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PubMed Mentions:
11
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Determining structure and action mechanism of LBF14 by molecular simulation. J Biomol Struct Dyn. 2022; 40(22):11977-11988.
Solbach F, Bernardi A, Bansal S, Budamagunta MS, Krep L, Leonhard K, Voss JC, Lam KS, Faller R. PMID: 34424133.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Transformable amyloid-beta mimetic peptide amphiphiles for lysosomal disruption in non-small cell lung cancer. Biomaterials. 2021 10; 277:121078.
Baehr CM, Zhang L, Wu Y, Domokos A, Xiao W, Wang L, Lam KS. PMID: 34461458; PMCID: PMC9969961.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Rapid discovery of self-assembling peptides with one-bead one-compound peptide library. Nat Commun. 2021 07 23; 12(1):4494.
Yang PP, Li YJ, Cao Y, Zhang L, Wang JQ, Lai Z, Zhang K, Shorty D, Xiao W, Cao H, Wang L, Wang H, Liu R, Lam KS. PMID: 34301935; PMCID: PMC8302598.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Development and Characterization of a Novel Peptide-Drug Conjugate with DM1 for Treatment of FGFR2-Positive Tumors. Biomedicines. 2021 Jul 21; 9(8).
Wang Y, Li Y, Cao J, Meng Q, Li X, Zhang Y, Lam KS, Hong A, Liu R, Chen X. PMID: 34440055; PMCID: PMC8389697.
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PubMed Mentions:
7
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The NIH Somatic Cell Genome Editing program. Nature. 2021 04; 592(7853):195-204.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J, SCGE Consortium. PMID: 33828315; PMCID: PMC8026397.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Mechanical Load Regulates Excitation-Ca2+ Signaling-Contraction in Cardiomyocyte. Circ Res. 2021 03 19; 128(6):772-774.
Shimkunas R, Hegyi B, Jian Z, Shaw JA, Kazemi-Lari MA, Mitra D, Leach JK, Li X, Jaradeh M, Balardi N, Chen YJ, Escobar AL, Baker AJ, Bossuyt J, Banyasz T, Chiamvimonvat N, Lam KS, Bers DM, Izu LT, Chen-Izu Y. PMID: 33601939; PMCID: PMC7979518.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Tumor Receptor-Mediated In Vivo Modulation of the Morphology, Phototherapeutic Properties, and Pharmacokinetics of Smart Nanomaterials. ACS Nano. 2021 01 26; 15(1):468-479.
Zhang L, Wu Y, Yin X, Zhu Z, Rojalin T, Xiao W, Zhang D, Huang Y, Li L, Baehr CM, Yu X, Ajena Y, Li Y, Wang L, Lam KS. PMID: 33332957.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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LHRH-Targeted Redox-Responsive Crosslinked Micelles Impart Selective Drug Delivery and Effective Chemotherapy in Triple-Negative Breast Cancer. Adv Healthc Mater. 2021 02; 10(3):e2001196.
Xiao K, Liu Q, Suby N, Xiao W, Agrawal R, Vu M, Zhang H, Luo Y, Li Y, Lam KS. PMID: 33200571; PMCID: PMC7858235.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation. BMC Pharmacol Toxicol. 2020 11 13; 21(1):76.
Jiang M, Liu L, Liu R, Lam KS, Lane NE, Yao W. PMID: 33187558; PMCID: PMC7664094.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591.
Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. PMID: 32929084; PMCID: PMC7490264.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Identification of osteogenic progenitor cell-targeted peptides that augment bone formation. Nat Commun. 2020 08 27; 11(1):4278.
Jiang M, Liu R, Liu L, Kot A, Liu X, Xiao W, Jia J, Li Y, Lam KS, Yao W. PMID: 32855388; PMCID: PMC7453024.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Developing an Injectable Nanofibrous Extracellular Matrix Hydrogel With an Integrin αvβ3 Ligand to Improve Endothelial Cell Survival, Engraftment and Vascularization. Front Bioeng Biotechnol. 2020; 8:890.
Hao D, Liu R, Gao K, He C, He S, Zhao C, Sun G, Farmer DL, Panitch A, Lam KS, Wang A. PMID: 32850742; PMCID: PMC7403189.
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PubMed Mentions:
6
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Extracellular Matrix Mimicking Nanofibrous Scaffolds Modified With Mesenchymal Stem Cell-Derived Extracellular Vesicles for Improved Vascularization. Front Bioeng Biotechnol. 2020; 8:633.
Hao D, Swindell HS, Ramasubramanian L, Liu R, Lam KS, Farmer DL, Wang A. PMID: 32671037; PMCID: PMC7329993.
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PubMed Mentions:
29
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View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging. Nat Nanotechnol. 2020 06; 15(6):482-490.
Wang Z, Xue X, Lu H, He Y, Lu Z, Chen Z, Yuan Y, Tang N, Dreyer CA, Quigley L, Curro N, Lam KS, Walton JH, Lin TY, Louie AY, Gilbert DA, Liu K, Ferrara KW, Li Y. PMID: 32451501; PMCID: PMC7307456.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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Structure-Activity Relationship of RGD-Containing Cyclic Octapeptide and αvβ3 Integrin Allows for Rapid Identification of a New Peptide Antagonist. Int J Mol Sci. 2020 Apr 27; 21(9).
Silva A, Xiao W, Wang Y, Wang W, Chang HW, Ames JB, Lam KS, Zhang Y. PMID: 32349271; PMCID: PMC7246635.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomater. 2020 05; 108:178-193.
Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. PMID: 32151698; PMCID: PMC8012081.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Surface modification of polymeric electrospun scaffolds via a potent and high-affinity integrin α4β1 ligand improved the adhesion, spreading and survival of human chorionic villus-derived mesenchymal stem cells: a new insight for fetal tissue engineering. J Mater Chem B. 2020 02 26; 8(8):1649-1659.
Hao D, Ma B, He C, Liu R, Farmer DL, Lam KS, Wang A. PMID: 32011618; PMCID: PMC7353926.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Sequential Targeting in Crosslinking Nanotheranostics for Tackling the Multibarriers of Brain Tumors. Adv Mater. 2020 Apr; 32(14):e1903759.
Wu H, Lu H, Xiao W, Yang J, Du H, Shen Y, Qu H, Jia B, Manna SK, Ramachandran M, Xue X, Ma Z, Xu X, Wang Z, He Y, Lam KS, Zawadzki RJ, Li Y, Lin TY. PMID: 32078198; PMCID: PMC7148201.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Size-Transformable Hyaluronan Stacked Self-Assembling Peptide Nanoparticles for Improved Transcellular Tumor Penetration and Photo-Chemo Combination Therapy. ACS Nano. 2020 02 25; 14(2):1958-1970.
Cong Z, Zhang L, Ma SQ, Lam KS, Yang FF, Liao YH. PMID: 32023048.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo. Nat Nanotechnol. 2020 02; 15(2):145-153.
Zhang L, Jing D, Jiang N, Rojalin T, Baehr CM, Zhang D, Xiao W, Wu Y, Cong Z, Li JJ, Li Y, Wang L, Lam KS. PMID: 31988501; PMCID: PMC7147967.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Tunable hydrogels for mesenchymal stem cell delivery: Integrin-induced transcriptome alterations and hydrogel optimization for human wound healing. Stem Cells. 2020 02; 38(2):231-245.
Marusina AI, Merleev AA, Luna JI, Olney L, Haigh NE, Yoon D, Guo C, Ovadia EM, Shimoda M, Luxardi G, Boddu S, Lal NN, Takada Y, Lam KS, Liu R, Isseroff RR, Le S, Nolta JA, Kloxin AM, Maverakis E. PMID: 31648388.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol Life Sci. 2020 Sep; 77(18):3597-3609.
Wang YZ, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ. PMID: 31758234; PMCID: PMC7242138.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Galectin-1 inhibition induces cell apoptosis through dual suppression of CXCR4 and Ras pathways in human malignant peripheral nerve sheath tumors. Neuro Oncol. 2019 11 04; 21(11):1389-1400.
Shih TC, Fan Y, Kiss S, Li X, Deng XN, Liu R, Chen XJ, Carney R, Chen A, Ghosh PM, Lam KS. PMID: 31127849; PMCID: PMC6827838.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Peptide-based materials for cancer immunotherapy. Theranostics. 2019; 9(25):7807-7825.
Zhang L, Huang Y, Lindstrom AR, Lin TY, Lam KS, Li Y. PMID: 31695802; PMCID: PMC6831480.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nat Commun. 2019 10 11; 10(1):4621.
Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW. PMID: 31604910; PMCID: PMC6789042.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer. Oncotarget. 2019 Sep 10; 10(52):5468-5479.
Yang F, Xiao W, Liu Y, Liu R, Kramer R, Li X, Ajena Y, Baehr CM, Rojalin T, Zhang H, Lam KS. PMID: 31534631; PMCID: PMC6739215.
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PubMed Mentions:
2 Fields:
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Correction to: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 Jul 26; 12(1):83.
Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31349855; PMCID: PMC6660960.
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PubMed Mentions:
1 Fields:
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High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 06 10; 12(1):56.
Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31182116; PMCID: PMC6558829.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Rapid Discovery of Illuminating Peptides for Instant Detection of Opioids in Blood and Body Fluids. Molecules. 2019 May 10; 24(9).
Jafari S, Thillier Y, Ajena YH, Shorty D, Li J, Huynh JS, Pan BM, Pan T, Lam KS, Liu R. PMID: 31083395; PMCID: PMC6539258.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia. Nanomedicine. 2019 08; 20:102004.
Lin TY, Zhu Y, Li Y, Zhang H, Ma AH, Long Q, Keck J, Lam KS, Pan CX, Jonas BA. PMID: 31055076; PMCID: PMC8237247.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 06; 24:101189.
Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. PMID: 30986607; PMCID: PMC6463934.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Affinity selection and sequencing. Nat Chem Biol. 2019 04; 15(4):320-321.
Lam KS. PMID: 30886435.
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PubMed Mentions:
1 Fields:
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Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma. Front Mol Biosci. 2019; 6:5.
Ngo T, Corrales A, Bourne T, Elmojahid S, Lam KS, Díaz E. PMID: 30838212; PMCID: PMC6390498.
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PubMed Mentions:
8
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Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. FASEB J. 2019 05; 33(5):5836-5849.
Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer DL, Wang A. PMID: 30753093; PMCID: PMC6463921.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro. ACS Appl Mater Interfaces. 2019 Feb 13; 11(6):5821-5833.
Wen H, Xiao W, Biswas S, Cong ZQ, Liu XM, Lam KS, Liao YH, Deng W. PMID: 30645095.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Combinatorial Peptide Microarray Synthesis Based on Microfluidic Impact Printing. ACS Comb Sci. 2019 01 14; 21(1):6-10.
Li J, Zhao S, Yang G, Liu R, Xiao W, Disano P, Lam KS, Pan T. PMID: 30521316; PMCID: PMC6335607.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy in vivo. Biomed Opt Express. 2019 Jan 01; 10(1):151-166.
Goswami M, Wang X, Zhang P, Xiao W, Karlen SJ, Li Y, Zawadzki RJ, Burns ME, Lam KS, Pugh EN. PMID: 30775090; PMCID: PMC6363190.
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PubMed Mentions:
4
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A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing. Anal Chem. 2018 12 04; 90(23):13969-13977.
Li J, Tan W, Xiao W, Carney RP, Men Y, Li Y, Quon G, Ajena Y, Lam KS, Pan T. PMID: 30358386; PMCID: PMC6467812.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Safety and Efficacy of Osimertinib in the Treatment of a Patient With Metastatic Lung Cancer and Concurrent Somatic EGFR L858R and Germline EGFR T790M Mutations. JCO Precis Oncol. 2018 Nov; 2:1-7.
Ma W, Gong J, Shan J, Lewis D, Xiao W, Moore EH, Zhang Y, Hung J, Mans NZ, Wei S, Welborn J, Stollenwerk NS, Lam KS, Li T. PMID: 35135138.
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PubMed Mentions:
4 Fields:
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Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer. Nano Lett. 2018 11 14; 18(11):7092-7103.
Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS. PMID: 30339018; PMCID: PMC6501589.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Identification of integrin drug targets for 17 solid tumor types. Oncotarget. 2018 Jul 10; 9(53):30146-30162.
Arun AS, Tepper CG, Lam KS. PMID: 30046394; PMCID: PMC6059022.
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PubMed Mentions:
11 Fields:
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Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy. Adv Funct Mater. 2018 Aug 15; 28(33).
Wang Z, Xue X, He Y, Lu Z, Jia B, Wu H, Yuan Y, Huang Y, Wang H, Lu H, Lam KS, Lin TY, Li Y. PMID: 31303869; PMCID: PMC6625784.
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PubMed Mentions:
9
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Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo. Nanomedicine (Lond). 2018 05; 13(10):1107-1120.
Wang XS, Zhang L, Li X, Kong DJ, Hu XC, Ding XZ, Yang JQ, Zhao MQ, He Y, Lam KS, Gao SG, Lin TY, Li Y. PMID: 29874151; PMCID: PMC6219431.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Reversibly disulfide cross-linked micelles improve the pharmacokinetics and facilitate the targeted, on-demand delivery of doxorubicin in the treatment of B-cell lymphoma. Nanoscale. 2018 May 03; 10(17):8207-8216.
Xiao K, Liu Q, Al Awwad N, Zhang H, Lai L, Luo Y, Lee JS, Li Y, Lam KS. PMID: 29682647; PMCID: PMC5980239.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion. Clin Cancer Res. 2018 09 01; 24(17):4319-4331.
Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss S, Wang T, Chen XJ, Carney R, Kung HJ, Duan Y, Ghosh PM, Lam KS. PMID: 29666302; PMCID: PMC6125207.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Microfluidic Print-to-Synthesis Platform for Efficient Preparation and Screening of Combinatorial Peptide Microarrays. Anal Chem. 2018 05 01; 90(9):5833-5840.
Li J, Carney RP, Liu R, Fan J, Zhao S, Chen Y, Lam KS, Pan T. PMID: 29633611.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Size-Modulable Nanoprobe for High-Performance Ultrasound Imaging and Drug Delivery against Cancer. ACS Nano. 2018 04 24; 12(4):3449-3460.
Zhang L, Yin T, Li B, Zheng R, Qiu C, Lam KS, Zhang Q, Shuai X. PMID: 29634240.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Reply to Letter to the Editor. Curr Opin Chem Biol. 2018 02; 42:187.
Lam KS. PMID: 29452736.
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PubMed Mentions: Fields:
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Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice. Biochem Biophys Res Commun. 2018 02 19; 496(4):1302-1307.
Yamagami T, Pleasure DE, Lam KS, Zhou CJ. PMID: 29410176; PMCID: PMC5816694.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Corrigendum to 'Tumor-targeting peptides from combinatorial libraries' [Adv Drug Deliv Rev.110-111 (2017) 13-37]. Adv Drug Deliv Rev. 2018 02 01; 125:152.
Liu R, Li X, Xiao W, Lam KS. PMID: 29530341.
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PubMed Mentions: Fields:
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Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model. Nanomedicine. 2018 04; 14(3):789-799.
Long Q, Lin TY, Huang Y, Li X, Ma AH, Zhang H, Carney R, Airhart S, Lam KS, deVere White RW, Pan CX, Li Y. PMID: 29317342; PMCID: PMC5898975.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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SERS analysis of selectively captured exosomes using an integrin-specific peptide ligand. Journal of Raman Spectroscopy. 2017 Dec 1; 48(12):1771-1776.
Lee LC, Carney CR, Lam LK, Chan CJ. .
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"One-Pot" Fabrication of Highly Versatile and Biocompatible Poly(vinyl alcohol)-porphyrin-based Nanotheranostics. Theranostics. 2017; 7(16):3901-3914.
Luo Y, Wu H, Feng C, Xiao K, Yang X, Liu Q, Lin TY, Zhang H, Walton JH, Ajena Y, Hu Y, Lam KS, Li Y. PMID: 29109786; PMCID: PMC5667413.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer. J Control Release. 2017 Oct 28; 264:169-179.
Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y. PMID: 28847739; PMCID: PMC5632596.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development. J Biol Chem. 2017 09 08; 292(36):15121-15132.
He W, Felderman M, Evans AC, Geng J, Homan D, Bourguet F, Fischer NO, Li Y, Lam KS, Noy A, Xing L, Cheng RH, Rasley A, Blanchette CD, Kamrud K, Wang N, Gouvis H, Peterson TC, Hubby B, Coleman MA. PMID: 28739800; PMCID: PMC5592686.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. J Control Release. 2017 09 10; 261:297-306.
Yang X, Xue X, Luo Y, Lin TY, Zhang H, Lac D, Xiao K, He Y, Jia B, Lam KS, Li Y. PMID: 28700898; PMCID: PMC5589441.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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A facile strategy for fine-tuning the stability and drug release of stimuli-responsive cross-linked micellar nanoparticles towards precision drug delivery. Nanoscale. 2017 Jun 14; 9(23):7765-7770.
Xiao K, Lin TY, Lam KS, Li Y. PMID: 28585953; PMCID: PMC5568647.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Single-Bead Quantification of Peptide Loading Distribution for One-Bead One-Compound Library Synthesis Using Confocal Raman Spectroscopy. Anal Chem. 2017 07 05; 89(13):7000-7008.
Tang Y, Thillier Y, Liu R, Li X, Lam KS, Gao T. PMID: 28530391.
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PubMed Mentions:
2 Fields:
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A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer. Acta Pharmacol Sin. 2017 Jun; 38(6):931-942.
Wang XS, Kong DJ, Lin TY, Li XC, Izumiya Y, Ding XZ, Zhang L, Hu XC, Yang JQ, Gao SG, Lam KS, Li YP. PMID: 28552907; PMCID: PMC5520194.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models. Oncotarget. 2017 May 09; 8(19):30742-30755.
Jian C, Tu MJ, Ho PY, Duan Z, Zhang Q, Qiu JX, DeVere White RW, Wun T, Lara PN, Lam KS, Yu AX, Yu AM. PMID: 28415566; PMCID: PMC5458164.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Combinatorial chemistry in drug discovery. Curr Opin Chem Biol. 2017 Jun; 38:117-126.
Liu R, Li X, Lam KS. PMID: 28494316; PMCID: PMC5645069.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimals
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Cholic acid-based novel micellar nanoplatform for delivering FDA-approved taxanes. Nanomedicine (Lond). 2017 May; 12(10):1153-1164.
Bharadwaj G, Nhan V, Yang S, Li X, Narayanan A, Macarenco AC, Shi Y, Yang D, Vieira LS, Xiao W, Li Y, Lam KS. PMID: 28447909; PMCID: PMC5480805.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Multispectral Optical Tweezers for Biochemical Fingerprinting of CD9-Positive Exosome Subpopulations. Anal Chem. 2017 05 16; 89(10):5357-5363.
Carney RP, Hazari S, Colquhoun M, Tran D, Hwang B, Mulligan MS, Bryers JD, Girda E, Leiserowitz GS, Smith ZJ, Lam KS. PMID: 28345878; PMCID: PMC5551404.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Combinatorial Library Screening with Liposomes for Discovery of Membrane Active Peptides. ACS Comb Sci. 2017 05 08; 19(5):299-307.
Carney RP, Thillier Y, Kiss Z, Sahabi A, Heleno Campos JC, Knudson A, Liu R, Olivos D, Saunders M, Tian L, Lam KS. PMID: 28378995; PMCID: PMC5901688.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo. Mol Cancer Ther. 2017 07; 16(7):1212-1223.
Shih TC, Liu R, Fung G, Bhardwaj G, Ghosh PM, Lam KS. PMID: 28396365; PMCID: PMC5516795.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis. Biosci Rep. 2017 04 28; 37(2).
Mori S, Hatori N, Kawaguchi N, Hamada Y, Shih TC, Wu CY, Lam KS, Matsuura N, Yamamoto H, Takada YK, Takada Y. PMID: 28302677; PMCID: PMC5482197.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides. Adv Biosyst. 2017 May; 1(5).
Carney RP, Hazari S, Rojalin T, Knudson A, Gao T, Tang Y, Liu R, Viitala T, Yliperttula M, Lam KS. PMID: 29911169; PMCID: PMC6001286.
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PubMed Mentions:
22 Fields:
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ITK inhibition for the targeted treatment of CTCL. J Dermatol Sci. 2017 Jul; 87(1):88-91.
Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E. PMID: 28434812; PMCID: PMC6459605.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 04 21; 12(4):1075-1086.
Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. PMID: 28195700; PMCID: PMC5875449.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Multimodal second harmonic generation and two photon fluorescence imaging of microdomain calcium contraction coupling in single cardiomyocytes. Proceedings of SPIE. 2016 Nov 24; 10013:1001304-1001304-7.
Chan CJ, Awasthi AS, Izu IL, Mao MZ, Jian JZ, Landas LT, Lerner LA, Shimkunas SR, Woldeyesus WR, Bossuyt BJ, Wood WB, Chen CY, Matthews MD, Lieu LD, Chiamvimonvat CN, Lam LK, Chen-Izu CY. .
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Disulfide-crosslinked nanomicelles confer cancer-specific drug delivery and improve efficacy of paclitaxel in bladder cancer. Nanotechnology. 2016 Oct 21; 27(42):425103.
Pan A, Zhang H, Li Y, Lin TY, Wang F, Lee J, Cheng M, Dall'Era M, Li T, deVere White R, Pan CX, Lam KS. PMID: 27640312; PMCID: PMC6522262.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Developing a Nanoparticle-Delivered High-Efficacy Treatment for Infantile Hemangiomas Using a Mouse Hemangioendothelioma Model. Plast Reconstr Surg. 2016 Aug; 138(2):410-417.
Orbay H, Li Y, Xiao W, Cherry SR, Lam K, Sahar DE. PMID: 27465164; PMCID: PMC5472049.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer. Biomaterials. 2016 10; 104:339-51.
Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX. PMID: 27479049; PMCID: PMC5412594.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference. Stem Cells. 2016 10; 34(10):2587-2600.
Yao W, Lay YE, Kot A, Liu R, Zhang H, Chen H, Lam K, Lane NE. PMID: 27334693; PMCID: PMC5690802.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nat Med. 2016 06 07; 22(6):692.
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW. PMID: 27270780.
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PubMed Mentions:
5 Fields:
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HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy. Theranostics. 2016; 6(9):1324-35.
Lin TY, Guo W, Long Q, Ma A, Liu Q, Zhang H, Huang Y, Chandrasekaran S, Pan C, Lam KS, Li Y. PMID: 27375782; PMCID: PMC4924502.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Tumor-targeting peptides from combinatorial libraries. Adv Drug Deliv Rev. 2017 02; 110-111:13-37.
Liu R, Li X, Xiao W, Lam KS. PMID: 27210583; PMCID: PMC5856482.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening. ACS Comb Sci. 2016 06 13; 18(6):320-9.
Wu CY, Wang DH, Wang X, Dixon SM, Meng L, Ahadi S, Enter DH, Chen CY, Kato J, Leon LJ, Ramirez LM, Maeda Y, Reis CF, Ribeiro B, Weems B, Kung HJ, Lam KS. PMID: 27053324; PMCID: PMC4908505.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nat Med. 2016 05; 22(5):488-96.
Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, Xu Y, Chen HW. PMID: 27019329; PMCID: PMC5030109.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors. EJNMMI Res. 2016 Dec; 6(1):18.
Xiao W, Li T, Bononi FC, Lac D, Kekessie IA, Liu Y, Sanchez E, Mazloom A, Ma AH, Lin J, Tran J, Yang K, Lam KS, Liu R. PMID: 26922417; PMCID: PMC4769701.
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PubMed Mentions:
15
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Chemically activatable viral capsid functionalized for cancer targeting. Nanomedicine (Lond). 2016 Feb; 11(4):377-90.
Chen CC, Xing L, Stark M, Ou T, Holla P, Xiao K, Kamita SG, Hammock BD, Lam K, Cheng RH. PMID: 26786134; PMCID: PMC4910953.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin. Mol Cancer Ther. 2016 Feb; 15(2):232-40.
Wang Y, Xiao W, Zhang Y, Meza L, Tseng H, Takada Y, Ames JB, Lam KS. PMID: 26719578; PMCID: PMC4747864.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Covalent Chemical Ligation Strategy for Mono- and Polyclonal Immunoglobulins at Their Nucleotide Binding Sites. Bioconjug Chem. 2016 Jan 20; 27(1):159-69.
Lac D, Feng C, Bhardwaj G, Le H, Tran J, Xing L, Fung G, Liu R, Cheng H, Lam KS. PMID: 26630124.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content. J Extracell Vesicles. 2015; 4:28533.
Smith ZJ, Lee C, Rojalin T, Carney RP, Hazari S, Knudson A, Lam K, Saari H, Ibañez EL, Viitala T, Laaksonen T, Yliperttula M, Wachsmann-Hogiu S. PMID: 26649679; PMCID: PMC4673914.
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PubMed Mentions:
123 Fields:
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Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes. Circ Res. 2016 01 22; 118(2):e19-28.
Awasthi S, Izu LT, Mao Z, Jian Z, Landas T, Lerner A, Shimkunas R, Woldeyesus R, Bossuyt J, Wood BM, Chen YJ, Matthews DL, Lieu DK, Chiamvimonvat N, Lam KS, Chen-Izu Y, Chan JW. PMID: 26643875; PMCID: PMC4740258.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Microfluidic-Enabled Print-to-Screen Platform for High-Throughput Screening of Combinatorial Chemotherapy. Anal Chem. 2015 Oct 20; 87(20):10166-71.
Ding Y, Li J, Xiao W, Xiao K, Lee J, Bhardwaj U, Zhu Z, Digiglio P, Yang G, Lam KS, Pan T. PMID: 26334956.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one-compound peptide libraries. Cell Mol Immunol. 2017 Mar; 14(3):308-318.
Leung NY, Wai CY, Ho MH, Liu R, Lam KS, Wang JJ, Shu SA, Chu KH, Leung PS. PMID: 26364917; PMCID: PMC5360880.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer. Biomaterials. 2015 Oct; 67:183-93.
Xiao K, Li YP, Wang C, Ahmad S, Vu M, Kuma K, Cheng YQ, Lam KS. PMID: 26218744; PMCID: PMC4550558.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia. J Am Soc Nephrol. 2016 Feb; 27(2):417-27.
Wang Y, Stokes A, Duan Z, Hui J, Xu Y, Chen Y, Chen HW, Lam K, Zhou CJ. PMID: 26047795; PMCID: PMC4731110.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization. J Pharmacol Exp Ther. 2015 Aug; 354(2):131-41.
Wang WP, Ho PY, Chen QX, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, Li T, Wun T, White RD, Lam KS, Yu AM. PMID: 26022002; PMCID: PMC4518075.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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3D plasmonic nanobowl platform for the study of exosomes in solution. Nanoscale. 2015; 7(20):9290-7.
Lee C, Carney RP, Hazari S, Smith ZJ, Knudson A, Robertson CS, Lam KS, Wachsmann-Hogiu S. PMID: 25939587.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Design, synthesis, and application of OB2C combinatorial peptide and peptidomimetic libraries. Methods Mol Biol. 2015; 1248:3-22.
Liu R, Shih TC, Deng X, Anwar L, Ahadi S, Kumaresan P, Lam KS. PMID: 25616322; PMCID: PMC4625904.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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In vivo wide-field multispectral scanning laser ophthalmoscopy-optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia, and Müller glia, and mapping of the mouse retinal and choroidal vasculature. J Biomed Opt. 2015; 20(12):126005.
Zhang P, Zam A, Jian Y, Wang X, Li Y, Lam KS, Burns ME, Sarunic MV, Pugh EN, Zawadzki RJ. PMID: 26677070; PMCID: PMC4681314.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells. Blood Cells Mol Dis. 2015 Apr; 54(4):329-35.
Barisone GA, Satake N, Lewis C, Duong C, Chen C, Lam KS, Nolta J, D?az E. PMID: 25554682; PMCID: PMC4387021.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1. J Biol Chem. 2015 Jan 02; 290(1):259-71.
Fujita M, Zhu K, Fujita CK, Zhao M, Lam KS, Kurth MJ, Takada YK, Takada Y. PMID: 25398877; PMCID: PMC4281730.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells. Proc Natl Acad Sci U S A. 2014 Nov 04; 111(44):E4789-96.
Tilley DC, Eum KS, Fletcher-Taylor S, Austin DC, Dupré C, Patrón LA, Garcia RL, Lam K, Yarov-Yarovoy V, Cohen BE, Sack JT. PMID: 25331865; PMCID: PMC4226076.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death Dis. 2014 Sep 04; 5:e1409.
Guo W, Liu R, Bhardwaj G, Yang JC, Changou C, Ma AH, Mazloom A, Chintapalli S, Xiao K, Xiao W, Kumaresan P, Sanchez E, Yeh CT, Evans CP, Patterson R, Lam KS, Kung HJ. PMID: 25188519; PMCID: PMC4540187.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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A smart and versatile theranostic nanomedicine platform based on nanoporphyrin. Nat Commun. 2014 Aug 26; 5:4712.
Li Y, Lin TY, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, Lam KS. PMID: 25158161; PMCID: PMC4145614.
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PubMed Mentions:
120 Fields:
Translation:
HumansAnimalsCells
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MXD3 regulation of DAOY cell proliferation dictated by time course of activation. BMC Cell Biol. 2014 Jul 23; 15:30.
Ngo T, Barisone GA, Lam KS, D?az E. PMID: 25053245; PMCID: PMC4226952.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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DETERMINATION OF BOVINE SERUM ALBUMIN CONJUGATED DRUGS BY IMMOBILIZATION AS MICROARRAYS AND OBLIQUE-INCIDENCE REFLECTIVITY DIFFERENCE MICROSCOPY. Instrumentation Science & Technology. 2014 Jul 4; 42(4):475-485.
Sun SY, Lam LK, Zhu ZX. .
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A structure-property relationship study of the well-defined telodendrimers to improve hemocompatibility of nanocarriers for anticancer drug delivery. Langmuir. 2014 Jun 17; 30(23):6878-88.
Shi C, Yuan D, Nangia S, Xu G, Lam KS, Luo J. PMID: 24849780; PMCID: PMC4063331.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Generating Encoded Compound Libraries for Fabricating Microarrays as a High-Throughput Protein Ligand Discovery Platform. Synthetic Communications. 2014 Apr 3; 44(7):987-1001.
Sun SY, Fei FY, Luo LJ, Dixon DS, Landry LJ, Lam LK, Zhu ZX. .
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Publisher Site Mentions:
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Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Sci Signal. 2014 Mar 18; 7(317):ra27.
Jian Z, Han H, Zhang T, Puglisi J, Izu LT, Shaw JA, Onofiok E, Erickson JR, Chen YJ, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff JC, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu Y. PMID: 24643800; PMCID: PMC4103414.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
-
Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014; 9(12):1807-20.
Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, Pan CX. PMID: 24628688; PMCID: PMC4167557.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Differentiation of cancer cell origin and molecular subtype by plasma membrane N-glycan profiling. J Proteome Res. 2014 Feb 07; 13(2):961-8.
Hua S, Saunders M, Dimapasoc LM, Jeong SH, Kim BJ, Kim S, So M, Lee KS, Kim JH, Lam KS, Lebrilla CB, An HJ. PMID: 24303873; PMCID: PMC3946297.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Photopatternable and photoactive hydrogel for on-demand generation of hydrogen peroxide in cell culture. Biomaterials. 2014 Feb; 35(5):1762-70.
Garland SP, Wang RY, Raghunathan VK, Lam KS, Murphy CJ, Russell P, Sun G, Pan T. PMID: 24290809; PMCID: PMC3992930.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
DETECTION OF FORMATION AND DISINTEGRATION OF MICELLES BY OBLIQUE-INCIDENCE REFLECTIVITY DIFFERENCE MICROSCOPY. Instrumentation Science & Technology. 2013 Nov 2; 41(6):130513113651003.
Sun SY, Luo LJ, Lam LK, Zhu ZX. .
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Publisher Site Mentions:
-
Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. PLoS One. 2013; 8(10):e77730.
Kenyon NJ, Bratt JM, Lee J, Luo J, Franzi LM, Zeki AA, Lam KS. PMID: 24204939; PMCID: PMC3808398.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Telodendrimer-based nanocarriers for the treatment of ovarian cancer. Ther Deliv. 2013 Oct; 4(10):1279-92.
Xiao K, Suby N, Li Y, Lam KS. PMID: 24116912; PMCID: PMC3936575.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Stimuli-responsive cross-linked micelles for on-demand drug delivery against cancers. Adv Drug Deliv Rev. 2014 Feb; 66:58-73.
Li Y, Xiao K, Zhu W, Deng W, Lam KS. PMID: 24060922; PMCID: PMC3947689.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimals
-
Reversing bone loss by directing mesenchymal stem cells to bone. Stem Cells. 2013 Sep; 31(9):2003-14.
Yao W, Guan M, Jia J, Dai W, Lay YA, Amugongo S, Liu R, Olivos D, Saunders M, Lam KS, Nolta J, Olvera D, Ritchie RO, Lane NE. PMID: 23818248; PMCID: PMC3795809.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. PLoS One. 2013; 8(8):e70910.
Guo W, Liu R, Bhardwaj G, Ma AH, Changou C, Yang JC, Li Y, Feng C, Luo Y, Mazloom A, Sanchez E, Wang Y, Huang W, Patterson R, Evans CP, Lam KS, Kung HJ. PMID: 23967135; PMCID: PMC3744530.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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The core-inversible micelles for hydrophilic drug delivery. Chem Commun (Camb). 2013 Jul 28; 49(59):6674-6.
Huang W, Shi C, Shao Y, Lam KS, Luo J. PMID: 23775217; PMCID: PMC3733992.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Antimitochondrial antibody recognition and structural integrity of the inner lipoyl domain of the E2 subunit of pyruvate dehydrogenase complex. J Immunol. 2013 Sep 01; 191(5):2126-33.
Wang J, Budamagunta MS, Voss JC, Kurth MJ, Lam KS, Lu L, Kenny TP, Bowlus C, Kikuchi K, Coppel RL, Ansari AA, Gershwin ME, Leung PS. PMID: 23894195; PMCID: PMC3759514.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
A novel peptide inhibitor attenuates C-reactive protein's pro-inflammatory effects in-vivo. Int J Cardiol. 2013 Oct 09; 168(4):3909-12.
Jialal I, Devaraj S, Smith G, Lam KS, Kumaresan PR. PMID: 23871616.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Immobilized OBOC combinatorial bead array to facilitate multiplicative screening. Comb Chem High Throughput Screen. 2013 Jul; 16(6):441-448.
Xiao W, Bononi FC, Townsend J, Li Y, Liu R, Lam KS. PMID: 23488896; PMCID: PMC4560360.
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PubMed Mentions:
4 Fields:
Translation:
Cells
-
Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Sci. 2013 Aug; 22(8):1078-86.
He W, Luo J, Bourguet F, Xing L, Yi SK, Gao T, Blanchette C, Henderson PT, Kuhn E, Malfatti M, Murphy WJ, Cheng RH, Lam KS, Coleman MA. PMID: 23754445; PMCID: PMC3832044.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning. Lab Chip. 2013 May 21; 13(10):1902-10.
Ding Y, Huang E, Lam KS, Pan T. PMID: 23525299; PMCID: PMC4565160.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid. Bioorg Med Chem. 2013 Aug 15; 21(16):4778-85.
Malekan H, Fung G, Thon V, Khedri Z, Yu H, Qu J, Li Y, Ding L, Lam KS, Chen X. PMID: 23535562; PMCID: PMC3722252.
View in:
PubMed Mentions:
21 Fields:
Translation:
Cells
-
Synthesis and characterization of a novel inhibitor of C-reactive protein-mediated proinflammatory effects. Metab Syndr Relat Disord. 2013 Jun; 11(3):177-84.
Kumaresan PR, Devaraj S, Huang W, Lau EY, Liu R, Lam KS, Jialal I. PMID: 23445482; PMCID: PMC3848264.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Single cell microRNA analysis using microfluidic flow cytometry. PLoS One. 2013; 8(1):e55044.
Wu M, Piccini M, Koh CY, Lam KS, Singh AK. PMID: 23383050; PMCID: PMC3559333.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. J Autoimmun. 2013 Mar; 41:79-86.
Leung PS, Wang J, Naiyanetr P, Kenny TP, Lam KS, Kurth MJ, Gershwin ME. PMID: 23352659; PMCID: PMC3622763.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer. Nanomedicine (Lond). 2013 Aug; 8(8):1239-51.
Lin TY, Li YP, Zhang H, Luo J, Goodwin N, Gao T, White Rde V, Lam KS, Pan CX. PMID: 23199207; PMCID: PMC3664656.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Discovery of specific ligands for oral squamous carcinoma to develop anti-cancer drug loaded precise targeting nanotherapeutics. J Calif Dent Assoc. 2012 Dec; 40(12):939-43.
Yang F, Liu R, Kramer R, Xiao W, Jordan R, Lam KS. PMID: 23362666; PMCID: PMC4562383.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Perspectives on clinical translation of smart nanotherapeutics. Ther Deliv. 2012 Dec; 3(12):1359-62.
Lee J, Lam KS. PMID: 23323552; PMCID: PMC4560357.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Solid-phase total synthesis of cherimolacyclopeptide E and discovery of more potent analogues by alanine screening. J Nat Prod. 2012 Nov 26; 75(11):1882-7.
Shaheen F, Rizvi TS, Musharraf SG, Ganesan A, Xiao K, Townsend JB, Lam KS, Choudhary MI. PMID: 23148652.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins. ACS Nano. 2012 Nov 27; 6(11):9485-95.
Li Y, Budamagunta MS, Luo J, Xiao W, Voss JC, Lam KS. PMID: 23106540; PMCID: PMC3922124.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. Bioorg Med Chem Lett. 2013 Jan 01; 23(1):340-5.
Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y. PMID: 23164706; PMCID: PMC4570851.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells. Clin Cancer Res. 2012 Dec 15; 18(24):6634-47.
Duru N, Fan M, Candas D, Menaa C, Liu HC, Nantajit D, Wen Y, Xiao K, Eldridge A, Chromy BA, Li S, Spitz DR, Lam KS, Wicha MS, Li JJ. PMID: 23091114; PMCID: PMC3593096.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis? Trends Mol Med. 2012 Oct; 18(10):577-82.
Leung PS, Lam K, Kurth MJ, Coppel RL, Gershwin ME. PMID: 22920894; PMCID: PMC3465509.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov; 82(5):938-47.
Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. PMID: 22899868; PMCID: PMC3477223.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Insonation of targeted microbubbles produces regions of reduced blood flow within tumor vasculature. Invest Radiol. 2012 Jul; 47(7):398-405.
Hu X, Kheirolomoom A, Mahakian LM, Beegle JR, Kruse DE, Lam KS, Ferrara KW. PMID: 22659591; PMCID: PMC3552613.
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PubMed Mentions:
33 Fields:
Translation:
Animals
-
Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. Int J Nanomedicine. 2012; 7:2793-804.
Lin TY, Zhang H, Luo J, Li Y, Gao T, Lara PN, de Vere White R, Lam KS, Pan CX. PMID: 22745542; PMCID: PMC3383352.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Disulfide cross-linked micelles for the targeted delivery of vincristine to B-cell lymphoma. Mol Pharm. 2012 Jun 04; 9(6):1727-35.
Kato J, Li Y, Xiao K, Lee JS, Luo J, Tuscano JM, O'Donnell RT, Lam KS. PMID: 22530955; PMCID: PMC4560237.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
-
Molecular targeting in childhood malignancies using nanoparticles. Proceedings of SPIE. 2012 May 1; 8373:83730n-83730n-6.
Satake SN, Barisone BG, Diaz DE, Nitin NN, Nolta NJ, Lam LK. .
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Publisher Site Mentions:
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In-vivo biodistribution and safety of 99mTc-LLP2A-HYNIC in canine non-Hodgkin lymphoma. PLoS One. 2012; 7(4):e34404.
Zwingenberger AL, Kent MS, Liu R, Kukis DL, Wisner ER, DeNardo SJ, Taylor SL, Chen X, Lam KS. PMID: 22545083; PMCID: PMC3335845.
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PubMed Mentions:
9 Fields:
Translation:
Animals
-
Molecular imaging of very late antigen-4 (α4β1 integrin) in the premetastatic niche. J Nucl Med. 2012 May; 53(5):779-86.
Shokeen M, Zheleznyak A, Wilson JM, Jiang M, Liu R, Ferdani R, Lam KS, Schwarz JK, Anderson CJ. PMID: 22496586; PMCID: PMC8522701.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer. Int J Nanomedicine. 2012; 7:1587-97.
Xiao W, Luo J, Jain T, Riggs JW, Tseng HP, Henderson PT, Cherry SR, Rowland D, Lam KS. PMID: 22605931; PMCID: PMC3352867.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
"OA02" peptide facilitates the precise targeting of paclitaxel-loaded micellar nanoparticles to ovarian cancer in vivo. Cancer Res. 2012 Apr 15; 72(8):2100-10.
Xiao K, Li Y, Lee JS, Gonik AM, Dong T, Fung G, Sanchez E, Xing L, Cheng HR, Luo J, Lam KS. PMID: 22396491; PMCID: PMC3343697.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
-
Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. Nat Med. 2012 Feb 05; 18(3):456-62.
Guan M, Yao W, Liu R, Lam KS, Nolta J, Jia J, Panganiban B, Meng L, Zhou P, Shahnazari M, Ritchie RO, Lane NE. PMID: 22306732; PMCID: PMC3755884.
View in:
PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols. Angew Chem Int Ed Engl. 2012 Mar 19; 51(12):2864-9.
Li Y, Xiao W, Xiao K, Berti L, Luo J, Tseng HP, Fung G, Lam KS. PMID: 22253091; PMCID: PMC3545653.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansCells
-
Investigation of the hydrodynamic behavior of diatom aggregates using particle image velocimetry. J Environ Sci (China). 2012; 24(7):1157-64.
Xiao F, Li X, Lam K, Wang D. PMID: 23513434.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells. Nanomedicine. 2012 Oct; 8(7):1116-24.
Zhang H, Luo J, Li Y, Henderson PT, Wang Y, Wachsmann-Hogiu S, Zhao W, Lam KS, Pan CX. PMID: 22197725; PMCID: PMC4577023.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Affinity of the alpha4-beta1 integrin-targeting peptide LLP2A to canine lymphoma. Vet Immunol Immunopathol. 2012 Jan 15; 145(1-2):298-304.
Zwingenberger AL, Kent MS, Shi C, Taylor SL, Chen X, Lam KS. PMID: 22177114; PMCID: PMC4159739.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Development of Cancer-Targeting Ligands and Ligand-Drug Conjugates. . 2011 Oct 19; 121-168.
Liu LR, Xiao XK, Luo LJ, Lam LK. .
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Publisher Site Mentions:
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PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell lymphoma. J Control Release. 2011 Oct 30; 155(2):272-81.
Xiao K, Luo J, Li Y, Lee JS, Fung G, Lam KS. PMID: 21787818; PMCID: PMC3196055.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
-
Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. J Autoimmun. 2011 Nov; 37(3):209-16.
Naiyanetr P, Butler JD, Meng L, Pfeiff J, Kenny TP, Guggenheim KG, Reiger R, Lam K, Kurth MJ, Ansari AA, Coppel RL, López-Hoyos M, Gershwin ME, Leung PS. PMID: 21763105; PMCID: PMC3206141.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Design Platforms of Nanocapsules for Human Therapeutics or Vaccines. . 2011 Jul 18; 125-139.
Kawano KM, Xing XL, Lam LK, Handa HH, Miyamura MT, Barnett BS, Srivastava SI, Cheng CR. .
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Publisher Site Mentions:
-
High-Resolution Imaging of Dendrimers Used in Drug Delivery via Scanning Probe Microscopy. J Drug Deliv. 2011; 2011:254095.
Shi L, Fleming CJ, Riechers SL, Yin NN, Luo J, Lam KS, Liu GY. PMID: 21773043; PMCID: PMC3134836.
View in:
PubMed Mentions:
5
-
Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery. Biomaterials. 2011 Sep; 32(27):6633-45.
Li Y, Xiao K, Luo J, Xiao W, Lee JS, Gonik AM, Kato J, Dong TA, Lam KS. PMID: 21658763; PMCID: PMC3137548.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
-
Novel flavonoids with antiproliferative activities against breast cancer cells. J Med Chem. 2011 Jul 14; 54(13):4339-49.
Yao N, Chen CY, Wu CY, Motonishi K, Kung HJ, Lam KS. PMID: 21599001; PMCID: PMC3169196.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Canine malignant melanoma alpha-3 integrin binding peptides. Vet Immunol Immunopathol. 2011 Sep 15; 143(1-2):11-9.
Aina OH, Maeda Y, Harrison M, Zwingenberger AL, Walker NJ, Lam KS, Kent MS. PMID: 21722969; PMCID: PMC4169883.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Nanoparticle targeted therapy against childhood acute lymphoblastic leukemia. Proceedings of SPIE. 2011 May 13; 8031:80311u-80311u-5.
Satake SN, Lee LJ, Xiao XK, Luo LJ, Sarangi SS, Chang CA, McLaughlin MB, Zhou ZP, Kenney KE, Kraynov KL, Arnott AS, McGee MJ, Nolta NJ, Lam LK. .
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Publisher Site Mentions:
-
Capillary-driven automatic packaging. Lab Chip. 2011 Apr 21; 11(8):1464-9.
Ding Y, Hong L, Nie B, Lam KS, Pan T. PMID: 21380434.
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PubMed Mentions:
4 Fields:
-
Alzheimer's disease drug candidates stabilize A-β protein native structure by interacting with the hydrophobic core. Biophys J. 2011 Feb 16; 100(4):1076-82.
Li J, Liu R, Lam KS, Jin LW, Duan Y. PMID: 21320453; PMCID: PMC3037571.
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PubMed Mentions:
8 Fields:
Translation:
Cells
-
Rapid discovery of death ligands with one-bead-two-compound combinatorial library methods. ACS Comb Sci. 2011 May 09; 13(3):259-64.
Kumaresan PR, Wang Y, Saunders M, Maeda Y, Liu R, Wang X, Lam KS. PMID: 21302937.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials. 2011 May; 32(13):3435-46.
Xiao K, Li Y, Luo J, Lee JS, Xiao W, Gonik AM, Agarwal RG, Lam KS. PMID: 21295849; PMCID: PMC3055170.
View in:
PubMed Mentions:
282 Fields:
Translation:
HumansAnimalsCells
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Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor. J Virol. 2011 Apr; 85(7):3283-93.
Chang PC, Fitzgerald LD, Hsia DA, Izumiya Y, Wu CY, Hsieh WP, Lin SF, Campbell M, Lam KS, Luciw PA, Tepper CG, Kung HJ. PMID: 21228229; PMCID: PMC3067885.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Maximization of loading and stability of ssDNA:iron oxide nanoparticle complexes formed through electrostatic interaction. Langmuir. 2010 Dec 07; 26(23):18293-9.
Berti L, Woldeyesus T, Li Y, Lam KS. PMID: 21047109; PMCID: PMC2994962.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Identification of a bladder cancer-specific ligand using a combinatorial chemistry approach. Urol Oncol. 2012 Sep; 30(5):635-45.
Zhang H, Aina OH, Lam KS, de Vere White R, Evans C, Henderson P, Lara PN, Wang X, Bassuk JA, Pan CX. PMID: 20888272; PMCID: PMC4572726.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Novel poly(ethylene-co-acrylic acid) nanofibrous biomaterials for peptide synthesis and biomedical applications. J Biomed Mater Res A. 2010 Oct; 95(1):245-55.
Xiang B, Sun G, Lam KS, Xiao K. PMID: 20597124.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
The use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handle. Mol Cancer Ther. 2010 Oct; 9(10):2714-23.
Xiao W, Wang Y, Lau EY, Luo J, Yao N, Shi C, Meza L, Tseng H, Maeda Y, Kumaresan P, Liu R, Lightstone FC, Takada Y, Lam KS. PMID: 20858725; PMCID: PMC3571112.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Jeffamine derivatized TentaGel beads and poly(dimethylsiloxane) microbead cassettes for ultrahigh-throughput in situ releasable solution-phase cell-based screening of one-bead-one-compound combinatorial small molecule libraries. J Comb Chem. 2010 Sep 13; 12(5):700-12.
Townsend JB, Shaheen F, Liu R, Lam KS. PMID: 20593859; PMCID: PMC3045263.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation. Carbohydr Res. 2010 Oct 13; 345(15):2277-81.
Yao N, Fung G, Malekan H, Ye L, Kurth MJ, Lam KS. PMID: 20832778; PMCID: PMC3207739.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for cancer treatment. Bioconjug Chem. 2010 Jul 21; 21(7):1216-24.
Luo J, Xiao K, Li Y, Lee JS, Shi L, Tan YH, Xing L, Holland Cheng R, Liu GY, Lam KS. PMID: 20536174; PMCID: PMC2912451.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
-
Halogenated benzimidazole carboxamides target integrin alpha4beta1 on T-cell and B-cell lymphomas. Cancer Res. 2010 Jul 01; 70(13):5448-56.
Carpenter RD, Natarajan A, Lau EY, Andrei M, Solano DM, Lightstone FC, Denardo SJ, Lam KS, Kurth MJ. PMID: 20530664; PMCID: PMC3166240.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
3-nitro-tyrosine as an internal quencher of autofluorescence enhances the compatibility of fluorescence based screening of OBOC combinatorial libraries. Comb Chem High Throughput Screen. 2010 Jun; 13(5):422-9.
Townsend J, Do A, Lehman A, Dixon S, Sanii B, Lam KS. PMID: 20236063.
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PubMed Mentions:
3 Fields:
Translation:
Cells
-
The Passive Targeting of Polymeric Micelles in Various Types and Sizes of Tumor Models. Nanoscience and Nanotechnology Letters. 2010 Jun 1; 2(2):79-85.
Xiao XK, Luo LJ, Li LY, Xiao XW, Lee LJ, Gonik GA, Lam LK. .
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Publisher Site Mentions:
-
From combinatorial chemistry to cancer targeting nanotherapeutics. Proceedings of SPIE. 2010 Apr 23; 7679:767909-767909-8.
Xiao XK, Luo LJ, Li LY, Xiao XW, Lee LJ, Gonik GA, Lam LK. .
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Publisher Site Mentions:
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A novel size-tunable nanocarrier system for targeted anticancer drug delivery. J Control Release. 2010 Jun 15; 144(3):314-23.
Li Y, Xiao K, Luo J, Lee J, Pan S, Lam KS. PMID: 20211210; PMCID: PMC2878919.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2550-5.
Maverakis E, Menezes JS, Ametani A, Han M, Stevens DB, He Y, Wang Y, Ono Y, Miyamura Y, Lam KS, Ward ES, Sercarz EE. PMID: 20133742; PMCID: PMC2823870.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCellsPHPublic Health
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Cholic acid micelles--controlling the size of the aqueous cavity by PEGylation. Phys Chem Chem Phys. 2010 Feb 21; 12(7):1589-94.
Despa F, Luo JT, Li J, Duan Y, Lam KS. PMID: 20126774.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope. J Biomed Opt. 2010 Jan-Feb; 15(1):016018.
Fei Y, Landry JP, Sun Y, Zhu X, Wang X, Luo J, Wu CY, Lam KS. PMID: 20210464; PMCID: PMC2839802.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer. 2010 Jan; 1(1):40-9.
Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, Kung HJ. PMID: 20811583; PMCID: PMC2930266.
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PubMed Mentions:
89
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Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific. J Biol Chem. 2010 Feb 19; 285(8):5266-73.
Chang PC, Izumiya Y, Wu CY, Fitzgerald LD, Campbell M, Ellison TJ, Lam KS, Luciw PA, Kung HJ. PMID: 20034935; PMCID: PMC2820755.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Functional fibrous polypropylene solid support and its application in solid phase peptide synthesis and cell specific binding. Reactive and Functional Polymers. 2009 Dec 1; 69(12):905-914.
Xiang XB, Lam LK, Sun SG. .
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Publisher Site Mentions:
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Structure-activity relationship studies of targeting ligands against breast cancer cells. J Med Chem. 2009 Nov 12; 52(21):6744-51.
Yao N, Xiao W, Meza L, Tseng H, Chuck M, Lam KS. PMID: 19835381.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
LAS0811: from combinatorial chemistry to activation of antioxidant response element. J Biomed Biotechnol. 2009; 2009:420194.
Zhu M, Baek H, Liu R, Song A, Lam K, Lau D. PMID: 19794825; PMCID: PMC2753787.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells. Mol Cancer Ther. 2009 Aug; 8(8):2441-51.
Nair RR, Emmons MF, Cress AE, Argilagos RF, Lam K, Kerr WT, Wang HG, Dalton WS, Hazlehurst LA. PMID: 19671765; PMCID: PMC2761715.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer. Biomaterials. 2009 Oct; 30(30):6006-16.
Xiao K, Luo J, Fowler WL, Li Y, Lee JS, Xing L, Cheng RH, Wang L, Lam KS. PMID: 19660809; PMCID: PMC2735593.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling. J Biol Chem. 2009 Sep 04; 284(36):24106-14.
Saegusa J, Yamaji S, Ieguchi K, Wu CY, Lam KS, Liu FT, Takada YK, Takada Y. PMID: 19578119; PMCID: PMC2782004.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support. Anal Chem. 2009 Jul 01; 81(13):5373-80.
Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS. PMID: 19563213; PMCID: PMC2751602.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies. J Nucl Med. 2009 Apr; 50(4):625-34.
Denardo SJ, Liu R, Albrecht H, Natarajan A, Sutcliffe JL, Anderson C, Peng L, Ferdani R, Cherry SR, Lam KS. PMID: 19289419.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin. J Med Chem. 2009 Jan 08; 52(1):14-9.
Carpenter RD, Andrei M, Aina OH, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. PMID: 19072684; PMCID: PMC3164867.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. J Med Chem. 2009 Jan 08; 52(1):126-33.
Yao N, Xiao W, Wang X, Marik J, Park SH, Takada Y, Lam KS. PMID: 19055415; PMCID: PMC2836207.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells. Biochem Biophys Res Commun. 2009 Feb 20; 379(4):876-81.
Kim TH, Venugopal SK, Zhu M, Wang SS, Lau D, Lam KS, Clemens DL, Zern MA. PMID: 19133235.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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On-demand cleavable linkers for radioimmunotherapy. Methods Mol Biol. 2009; 539:191-211.
Kumaresan PR, Luo J, Lam KS. PMID: 19377973.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Application of the "libraries from libraries" concept to "one-bead one-compound" combinatorial chemistry. Adv Exp Med Biol. 2009; 611:21-2.
Kappel JC, Fan YC, Lam KS. PMID: 19400077.
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PubMed Mentions: Fields:
Translation:
Cells
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A novel hydrogel functionalized with specific peptidomimetic ligands for 2-D and 3-D cell culture. Adv Exp Med Biol. 2009; 611:19-20.
Luo J, Onofiok E, Shi C, Liu R, Lam KS. PMID: 19400076.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Development of hydrogel TentaGel shell-core beads for ultrahigh throughput solution-phase screening of encoded OBOC combinatorial small molecule libraries. J Comb Chem. 2009 Jan-Feb; 11(1):91-102.
Baek HG, Liu R, Lam KS. PMID: 19061339; PMCID: PMC2693237.
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PubMed Mentions:
6 Fields:
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High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers. Cancer Biol Ther. 2008 Dec; 7(12):2015-22.
Park SH, Wang X, Liu R, Lam KS, Weiss RH. PMID: 18981726.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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An alpha4beta1 integrin antagonist decreases airway inflammation in ovalbumin-exposed mice. Eur J Pharmacol. 2009 Jan 28; 603(1-3):138-46.
Kenyon NJ, Liu R, O'Roark EM, Huang W, Peng L, Lam KS. PMID: 19103195; PMCID: PMC2646171.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Effect of fluorescently labeling protein probes on kinetics of protein-ligand reactions. Langmuir. 2008 Dec 02; 24(23):13399-405.
Sun YS, Landry JP, Fei YY, Zhu XD, Luo JT, Wang XB, Lam KS. PMID: 18991423; PMCID: PMC2721158.
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PubMed Mentions:
31 Fields:
Translation:
Animals
-
Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents. Neurobiol Aging. 2010 Oct; 31(10):1690-9.
Hong HS, Maezawa I, Budamagunta M, Rana S, Shi A, Vassar R, Liu R, Lam KS, Cheng RH, Hua DH, Voss JC, Jin LW. PMID: 19022536; PMCID: PMC2888733.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Asymmetric epoxidation, Michael addition, and triple cascade reaction using polymer-supported prolinol-based auxiliaries. Tetrahedron. 2008 Oct 1; 64(43):10087-10090.
Varela VM, Dixon DS, Lam LK, Schore SN. .
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Publisher Site Mentions:
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Near-infrared optical imaging in glioblastoma xenograft with ligand-targeting alpha 3 integrin. Eur J Nucl Med Mol Imaging. 2009 Jan; 36(1):94-103.
Xiao W, Yao N, Peng L, Liu R, Lam KS. PMID: 18712382; PMCID: PMC2842018.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology. 2008 Aug; 48(2):531-40.
Wakabayashi K, Lian ZX, Leung PS, Moritoki Y, Tsuneyama K, Kurth MJ, Lam KS, Yoshida K, Yang GX, Hibi T, Ansari AA, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME. PMID: 18563844; PMCID: PMC3753011.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCellsPHPublic Health
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Development of TNKase-specific cleavable peptide-linked radioimmunoconjugates for radioimmunotherapy. Bioorg Med Chem Lett. 2008 Sep 01; 18(17):4802-5.
Natarajan A, Kumaresan PR, Denardo SJ, Denardo GL, Mirick G, Lam KS. PMID: 18701282.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Glycoproteomic analyses of ovarian cancer cell lines and sera from ovarian cancer patients show distinct glycosylation changes in individual proteins. J Proteome Res. 2008 Sep; 7(9):3776-88.
Li B, An HJ, Kirmiz C, Lebrilla CB, Lam KS, Miyamoto S. PMID: 18642944.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol Chem. 2008 Sep 19; 283(38):26107-15.
Saegusa J, Akakura N, Wu CY, Hoogland C, Ma Z, Lam KS, Liu FT, Takada YK, Takada Y. PMID: 18635536; PMCID: PMC2533795.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Rainbow beads: a color coding method to facilitate high-throughput screening and optimization of one-bead one-compound combinatorial libraries. J Comb Chem. 2008 Jul-Aug; 10(4):599-604.
Luo J, Zhang H, Xiao W, Kumaresan PR, Shi C, Pan CX, Aina OH, Lam KS. PMID: 18558750.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates. Bioconjug Chem. 2008 Jun; 19(6):1313-8.
Kumaresan PR, Luo J, Song A, Marik J, Lam KS. PMID: 18494516.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling. J Biol Chem. 2008 Jun 27; 283(26):18066-75.
Mori S, Wu CY, Yamaji S, Saegusa J, Shi B, Ma Z, Kuwabara Y, Lam KS, Isseroff RR, Takada YK, Takada Y. PMID: 18441324; PMCID: PMC2440593.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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In vivo optical imaging of human lymphoma xenograft using a library-derived peptidomimetic against alpha4beta1 integrin. Mol Cancer Ther. 2008 Feb; 7(2):432-7.
Peng L, Liu R, Andrei M, Xiao W, Lam KS. PMID: 18245670.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Global transformation of OBOC combinatorial peptide libraries into OBOC polyamine and small molecule libraries. J Comb Chem. 2008 Mar-Apr; 10(2):333-42.
Kappel JC, Fan YC, Lam KS. PMID: 18181577.
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PubMed Mentions: Fields:
Translation:
Cells
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Discovery of high-affinity peptide ligands for vancomycin. Biopolymers. 2008; 90(3):421-32.
Yao N, Wu CY, Xiao W, Lam KS. PMID: 18260149.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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Asymmetric catalysis: resin-bound hydroxyprolylthreonine derivatives in enamine-mediated reactions. Angew Chem Int Ed Engl. 2008; 47(34):6407-10.
Carpenter RD, Fettinger JC, Lam KS, Kurth MJ. PMID: 18624312.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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A novel high-throughput scanning microscope for label-free detection of protein and small-molecule chemical microarrays. Rev Sci Instrum. 2008 Jan; 79(1):013708.
Fei YY, Landry JP, Sun YS, Zhu XD, Luo JT, Wang XB, Lam KS. PMID: 18248040; PMCID: PMC2715555.
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PubMed Mentions:
22 Fields:
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Glycomic approach for potential biomarkers on prostate cancer: profiling of N-linked glycans in human sera and pRNS cell lines. Dis Markers. 2008; 25(4-5):243-58.
de Leoz ML, An HJ, Kronewitter S, Kim J, Beecroft S, Vinall R, Miyamoto S, de Vere White R, Lam KS, Lebrilla C. PMID: 19126968; PMCID: PMC3827814.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Screening of a one bead-one compound combinatorial library for beta-actin identifies molecules active toward Ramos B-lymphoma cells. Anal Biochem. 2008 Mar 01; 374(1):112-20.
Miyamoto S, Liu R, Hung S, Wang X, Lam KS. PMID: 18023409; PMCID: PMC2770001.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Congo red and thioflavin-T analogs detect Abeta oligomers. J Neurochem. 2008 Jan; 104(2):457-68.
Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. PMID: 17953662.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Highly potent, water soluble benzimidazole antagonist for activated alpha 4 beta 1 integrin. J Med Chem. 2007 Nov 15; 50(23):5863-7.
Carpenter RD, Andrei M, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. PMID: 17948981.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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From combinatorial chemistry to cancer-targeting peptides. Mol Pharm. 2007 Sep-Oct; 4(5):631-51.
Aina OH, Liu R, Sutcliffe JL, Marik J, Pan CX, Lam KS. PMID: 17880166.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimals
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Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. J Immunol. 2007 Aug 15; 179(4):2651-7.
Leung PS, Park O, Tsuneyama K, Kurth MJ, Lam KS, Ansari AA, Coppel RL, Gershwin ME. PMID: 17675529.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Selecting an intervention time for intravascular enzymatic cleavage of peptide linkers to clear radioisotope from normal tissues. Cancer Biother Radiopharm. 2007 Aug; 22(4):556-63.
Siantar CL, DeNardo GL, Lam K, Yuan A, Daly T, DeNardo SJ. PMID: 17803451.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Glycomics analysis of serum: a potential new biomarker for ovarian cancer? Int J Gynecol Cancer. 2008 May-Jun; 18(3):470-5.
Leiserowitz GS, Lebrilla C, Miyamoto S, An HJ, Duong H, Kirmiz C, Li B, Liu H, Lam KS. PMID: 17655680; PMCID: PMC2581843.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Synthesis of flavonoid analogues as scaffolds for natural product-based combinatorial libraries. J Comb Chem. 2007 Jul-Aug; 9(4):668-76.
Yao N, Song A, Wang X, Dixon S, Lam KS. PMID: 17487987.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells. Oncogene. 2007 Sep 27; 26(44):6431-41.
Wang N, Lin KK, Lu Z, Lam KS, Newton R, Xu X, Yu Z, Gill GN, Andersen B. PMID: 17452977.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Oblique-incidence reflectivity difference microscope for label-free high-throughput detection of biochemical reactions in a microarray format. Appl Opt. 2007 Apr 01; 46(10):1890-5.
Zhu X, Landry JP, Sun YS, Gregg JP, Lam KS, Guo X. PMID: 17356635; PMCID: PMC2754717.
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PubMed Mentions:
21 Fields:
-
Microwave-mediated heterocyclization to benzimidazo[2,1-b]quinazolin-12(5H)-ones. J Org Chem. 2007 Jan 05; 72(1):284-7.
Carpenter RD, Lam KS, Kurth MJ. PMID: 17194113.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Development of tissue plasminogen activator specific "on demand cleavable" (odc) linkers for radioimmunotherapy by screening one-bead-one-compound combinatorial peptide libraries. Bioconjug Chem. 2007 Jan-Feb; 18(1):175-82.
Kumaresan PR, Natarajan A, Song A, Wang X, Liu R, DeNardo G, DeNardo S, Lam KS. PMID: 17226971.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. J Comb Chem. 2007 Jan-Feb; 9(1):143-57.
Dixon SM, Milinkevich KA, Fujii J, Liu R, Yao N, Lam KS, Kurth MJ. PMID: 17206843.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design. J Med Chem. 2006 Dec 14; 49(25):7413-26.
Dixon S, Ziebart KT, He Z, Jeddeloh M, Yoo CL, Wang X, Lehman A, Lam KS, Toney MD, Kurth MJ. PMID: 17149871.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity. Brain Res. 2007 Jan 26; 1130(1):223-34.
Hong HS, Maezawa I, Yao N, Xu B, Diaz-Avalos R, Rana S, Hua DH, Cheng RH, Lam KS, Jin LW. PMID: 17157826; PMCID: PMC1880896.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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The minimum element of a synthetic peptide required to block prostate tumor cell migration. Cancer Biol Ther. 2006 Nov; 5(11):1556-62.
Sroka TC, Marik J, Pennington ME, Lam KS, Cress AE. PMID: 17102593; PMCID: PMC2704570.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP. J Virol. 2007 Feb; 81(3):1072-82.
Izumiya Y, Izumiya C, Van Geelen A, Wang DH, Lam KS, Luciw PA, Kung HJ. PMID: 17108053; PMCID: PMC1797516.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Carbodiimide-based benzimidazole library method. J Comb Chem. 2006 Nov-Dec; 8(6):907-14.
Carpenter RD, Deberdt PB, Lam KS, Kurth MJ. PMID: 17096580.
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PubMed Mentions:
9 Fields:
Translation:
Cells
-
Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun. 2006 Aug; 27(1):7-16.
Rieger R, Leung PS, Jeddeloh MR, Kurth MJ, Nantz MH, Lam KS, Barsky D, Ansari AA, Coppel RL, Mackay IR, Gershwin ME. PMID: 16876981.
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PubMed Mentions:
56 Fields:
Translation:
HumansCellsPHPublic Health
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A serum glycomics approach to breast cancer biomarkers. Mol Cell Proteomics. 2007 Jan; 6(1):43-55.
Kirmiz C, Li B, An HJ, Clowers BH, Chew HK, Lam KS, Ferrige A, Alecio R, Borowsky AD, Sulaimon S, Lebrilla CB, Miyamoto S. PMID: 16847285.
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PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Profiling of glycans in serum for the discovery of potential biomarkers for ovarian cancer. J Proteome Res. 2006 Jul; 5(7):1626-35.
An HJ, Miyamoto S, Lancaster KS, Kirmiz C, Li B, Lam KS, Leiserowitz GS, Lebrilla CB. PMID: 16823970.
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PubMed Mentions:
93 Fields:
Translation:
HumansCells
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Image subtraction approach to screening one-bead-one-compound combinatorial libraries with complex protein mixtures. J Comb Chem. 2006 Jul-Aug; 8(4):562-70.
Lehman A, Gholami S, Hahn M, Lam KS. PMID: 16827569.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. Nat Chem Biol. 2006 Jul; 2(7):381-9.
Peng L, Liu R, Marik J, Wang X, Takada Y, Lam KS. PMID: 16767086.
View in:
PubMed Mentions:
128 Fields:
Translation:
HumansAnimalsCells
-
LMO4 can interact with Smad proteins and modulate transforming growth factor-beta signaling in epithelial cells. Oncogene. 2006 May 11; 25(20):2920-30.
Lu Z, Lam KS, Wang N, Xu X, Cortes M, Andersen B. PMID: 16331278.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Facile solid-phase synthesis of 2,3-disubstituted 6H-pyrano[2,3-f]benzimidazole-6-ones. Tetrahedron. 2006 May 1; 62(18):4393-4399.
Song SA, Wu WL, Ho HL, Lam LK. .
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Publisher Site Mentions:
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Peptide ligands targeting integrin alpha3beta1 in non-small cell lung cancer. Lung Cancer. 2006 Jun; 52(3):291-7.
Lau D, Guo L, Liu R, Marik J, Lam K. PMID: 16635537.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. J Med Chem. 2006 Apr 20; 49(8):2388-97.
Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. PMID: 16610782.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Screening chemical microarrays: methods and applications. Mol Biosyst. 2006 May; 2(5):259-70.
Kumaresan PR, Lam KS. PMID: 16880944.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Structure-activity relationship studies of a series of peptidomimetic ligands for alpha(4) beta(1) integrin on Jurkat T-leukemia cells. Biopolymers. 2006; 84(6):595-604.
Liu R, Peng L, Han H, Lam KS. PMID: 17041919.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Ultrasound Radiation Force Enables Targeted Deposition of Molecularly Targeted Nanoparticles Loaded on Microbubbles Under Flow Conditions. . 2006 Jan 1; 108-111.
Lum LA, Borden BM, Dayton DP, Peng PL, Kruse KD, Simon SS, Lam LK, Ferrara FK. .
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Publisher Site Mentions:
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Development and Applications of Topologically Segregated Bilayer Beads in One-bead One-compound Combinatorial Libraries. Molecular Informatics. 2005 Dec 1; 24(10):1127-1140.
Liu LR, Wang WX, Song SA, Bao BT, Lam LK. .
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Publisher Site Mentions:
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Solid-phase synthesis of quinoxaline, thiazine, and oxazine analogs through a benzyne intermediate. Tetrahedron Letters. 2005 Oct 1; 46(43):7443-7446.
Dixon DS, Wang WX, Lam LK, Kurth KM. .
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Publisher Site Mentions:
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Near-infrared optical imaging of ovarian cancer xenografts with novel alpha 3-integrin binding peptide "OA02". Mol Imaging. 2005 Oct-Dec; 4(4):439-47.
Aina OH, Marik J, Gandour-Edwards R, Lam KS. PMID: 16285906.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Traceless solid-phase synthesis of 1,4-disubstituted-6-nitro-3,4-dihydro-1H-quinoline-2-ones. Tetrahedron Letters. 2005 Aug 1; 46(32):5361-5364.
Wang WX, Dixon DS, Kurth KM, Lam LK. .
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Publisher Site Mentions:
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Microwave assisted DIC-promoted intramolecular cyclization for solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones. Tetrahedron Letters. 2005 Aug 1; 46(34):5747-5750.
Wang WX, Dixon DS, Yao YN, Kurth KM, Lam LK. .
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Publisher Site Mentions:
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Discovery of selective aldo-keto reductase ligands--an on-bead assay strategy. Bioorg Med Chem Lett. 2005 Jun 02; 15(11):2938-42.
Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, Kurth MJ. PMID: 15911284.
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PubMed Mentions: Fields:
-
Solid-phase synthesis and antibacterial evaluations of N-demethylvancomycin derivatives. Bioorg Med Chem Lett. 2005 May 02; 15(9):2325-9.
Yao NH, Liu G, He WY, Niu C, Carlson JR, Lam KS. PMID: 15837318.
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PubMed Mentions: Fields:
Translation:
Cells
-
Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol. 2005 May 01; 174(9):5874-83.
Amano K, Leung PS, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Matsuura E, Coppel RL, Gershwin ME. PMID: 15845458.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansCellsPHPublic Health
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A topologically segregated one-bead-one-compound combinatorial glycopeptide library for identification of lectin ligands. J Comb Chem. 2005 May-Jun; 7(3):372-84.
Ying L, Liu R, Zhang J, Lam K, Lebrilla CB, Gervay-Hague J. PMID: 15877466.
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PubMed Mentions:
5 Fields:
Translation:
Cells
-
Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries. Mol Cancer Ther. 2005 May; 4(5):806-13.
Aina OH, Marik J, Liu R, Lau DH, Lam KS. PMID: 15897245.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Meeting report: high-throughput technologies for in vivo imaging agents. Mol Imaging. 2005 Apr-Jun; 4(2):98-103.
Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan DC, Weissleder R. PMID: 16105507.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Partial alloc-deprotection approach for ladder synthesis of "one-bead one-compound" combinatorial libraries. J Comb Chem. 2005 Mar-Apr; 7(2):197-209.
Wang X, Peng L, Liu R, Gill SS, Lam KS. PMID: 15762747.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Conformational studies of resin-bound vancomycin and the complex of vancomycin and Ac2-L-Lys-D-Ala-D-Ala. J Comb Chem. 2005 Jan-Feb; 7(1):123-9.
Yao NH, He WY, Lam KS, Liu G. PMID: 15638491.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Peptide and small-molecule microarrays. Methods Mol Biol. 2005; 310:217-26.
Marik J, Lam KS. PMID: 16353378.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Applications of topologically segregated bilayer beads in 'one-bead one-compound' combinatorial libraries. J Pept Res. 2005 Jan; 65(1):130-8.
Wang X, Peng L, Liu R, Xu B, Lam KS. PMID: 15686543.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Facile solid phase synthesis of 1,2-disubstituted-6-nitro-1,4-dihydroquinazolines using a tetrafunctional scaffold. Tetrahedron Letters. 2005 Jan 1; 46(3):427-430.
Wang WX, Song SA, Dixon DS, Kurth KM, Lam LK. .
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Publisher Site Mentions:
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OBOC small-molecule combinatorial library encoded by halogenated mass-tags. Org Lett. 2004 Oct 14; 6(21):3829-32.
Hwang SH, Lehman A, Cong X, Olmstead MM, Lam KS, Lebrilla CB, Kurth MJ. PMID: 15469360.
View in:
PubMed Mentions:
2 Fields:
-
Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells. Mol Cancer Ther. 2004 Oct; 3(10):1329-34.
Mikawa M, Wang H, Guo L, Liu R, Marik J, Takada Y, Lam K, Lau D. PMID: 15486200.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
An evaluation of barriers to accrual in the era of legislation requiring insurance coverage of cancer clinical trial costs in California. Cancer J. 2004 Sep-Oct; 10(5):294-300.
Martel CL, Li Y, Beckett L, Chew H, Christensen S, Davies A, Lam KS, Lau DH, Meyers FJ, O'donnell RT, Richman C, Scudder S, Tanaka M, Tuscano J, Welborn J, Wun T, Gandara DR, Lara PN. PMID: 15530258.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Parallel solid-phase synthesis of 2-arylamino-6H-pyrano[2,3-f]benzimidazole-6-ones. Tetrahedron. 2004 Sep 1; 60(39):8605-8612.
Song SA, Lam LK. .
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Publisher Site Mentions:
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Solid-phase synthesis and spectral properties of 2-alkylthio-6H-pyrano[2,3-f]benzimidazole-6-ones: a combinatorial approach for 2-alkylthioimidazocoumarins. J Comb Chem. 2004 Jul-Aug; 6(4):604-10.
Song A, Zhang J, Lebrilla CB, Lam KS. PMID: 15244422.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. J Immunol. 2004 May 15; 172(10):6444-52.
Amano K, Leung PS, Xu Q, Marik J, Quan C, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Coppel RL, Gershwin ME. PMID: 15128836.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
-
Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags. J Am Chem Soc. 2004 May 12; 126(18):5740-9.
Wang X, Zhang J, Song A, Lebrilla CB, Lam KS. PMID: 15125667.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Solid-phase synthesis of O-glycosylated Nalpha-Fmoc amino acids and analysis by high-resolution magic angle spinning NMR. J Comb Chem. 2004 Mar-Apr; 6(2):214-9.
Yao NH, He WY, Lam KS, Liu G. PMID: 15002969.
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PubMed Mentions: Fields:
Translation:
Cells
-
Solid-phase synthesis of 3-alkyl-2-arylamino-3,4-dihydroquinazolines. Tetrahedron Letters. 2004 Mar 1; 45(13):2727-2730.
Song SA, Mari´k MJ, Lam LK. .
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Publisher Site Mentions:
-
New approaches in identifying drugs to inactivate oncogene products. Semin Cancer Biol. 2004 Feb; 14(1):13-21.
Liu R, Hsieh CY, Lam KS. PMID: 14757532.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
Synthesis of hydrophilic and flexible linkers for peptide derivatization in solid phase. Bioorg Med Chem Lett. 2004 Jan 05; 14(1):161-5.
Song A, Wang X, Zhang J, Marík J, Lebrilla CB, Lam KS. PMID: 14684320.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
-
Synthesis and reactions of 7-fluoro-4-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-carboxylic acid: a novel scaffold for combinatorial synthesis of coumarins. J Comb Chem. 2004 Jan-Feb; 6(1):112-20.
Song A, Zhang J, Lam KS. PMID: 14714994.
View in:
PubMed Mentions:
1 Fields:
-
A novel approach to chemical microarray using ketone-modified macromolecular scaffolds: application in micro cell-adhesion assay. Mol Divers. 2004; 8(3):301-10.
Xu Q, Miyamoto S, Lam KS. PMID: 15384423.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Development and characterization of potent and specific peptide inhibitors of p60c-src protein tyrosine kinase using pseudosubstrate-based inhibitor design approach. J Pept Res. 2003 Dec; 62(6):260-8.
Kamath JR, Liu R, Enstrom AM, Lou Q, Lam KS. PMID: 14632929.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates. Clin Cancer Res. 2003 Sep 01; 9(10 Pt 2):3865S-72S.
DeNardo GL, DeNardo SJ, Peterson JJ, Miers LA, Lam KS, Hartmann-Siantar C, Lamborn KR. PMID: 14506184.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice. Clin Cancer Res. 2003 Sep 01; 9(10 Pt 2):3854S-64S.
DeNardo SJ, Yao Z, Lam KS, Song A, Burke PA, Mirick GR, Lamborn KR, O'Donnell RT, DeNardo GL. PMID: 14506183.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
Magnetization of large polystyrene peptide beads for capturing and expanding cancer cells. Journal of Magnetism and Magnetic Materials. 2003 Aug 1; 264(2-3):153-157.
Mari´k MJ, Lau LD, Song SA, Wang WX, Liu LR, Lam LK. .
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Publisher Site Mentions:
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Detection of primary aromatic amines on solid phase. Tetrahedron Letters. 2003 Jun 1; 44(23):4319-4320.
Mari´k MJ, Song SA, Lam LK. .
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Publisher Site Mentions:
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Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research. Acc Chem Res. 2003 Jun; 36(6):370-7.
Lam KS, Liu R, Miyamoto S, Lehman AL, Tuscano JM. PMID: 12809522.
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PubMed Mentions:
30 Fields:
Translation:
Cells
-
A novel and rapid encoding method based on mass spectrometry for "one-bead-one-compound" small molecule combinatorial libraries. J Am Chem Soc. 2003 May 21; 125(20):6180-8.
Song A, Zhang J, Lebrilla CB, Lam KS. PMID: 12785850.
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PubMed Mentions:
20 Fields:
-
Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. J Immunol. 2003 May 15; 170(10):5326-32.
Leung PS, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin ME. PMID: 12734383.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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High-throughput one-bead-one-compound approach to peptide-encoded combinatorial libraries: MALDI-MS analysis of single TentaGel beads. J Comb Chem. 2003 Mar-Apr; 5(2):125-37.
Franz AH, Liu R, Song A, Lam KS, Lebrilla CB. PMID: 12625702.
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PubMed Mentions:
12 Fields:
Translation:
Cells
-
A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes or ketones. Tetrahedron Letters. 2003 Feb 1; 44(9):1755-1758.
Song SA, Wang WX, Lam LK. .
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Publisher Site Mentions:
-
Synthesis and screening of "one-bead one-compound" combinatorial peptide libraries. Methods Enzymol. 2003; 369:298-322.
Lam KS, Lehman AL, Song A, Doan N, Enstrom AM, Maxwell J, Liu R. PMID: 14722961.
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PubMed Mentions:
21 Fields:
Translation:
Cells
-
Combinatorial peptide library methods for immunobiology research. Exp Hematol. 2003 Jan; 31(1):11-30.
Liu R, Enstrom AM, Lam KS. PMID: 12543103.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
-
Design, synthesis, screening, and decoding of encoded one-bead one-compound peptidomimetic and small molecule combinatorial libraries. Methods Enzymol. 2003; 369:271-87.
Liu R, Marik J, Lam KS. PMID: 14722959.
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PubMed Mentions: Fields:
Translation:
Cells
-
Protein and Chemical Microarrays-Powerful Tools for Proteomics. J Biomed Biotechnol. 2003; 2003(5):257-266.
Xu Q, Lam KS. PMID: 14688413; PMCID: PMC521501.
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PubMed Mentions:
11 Fields:
-
Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives. J Org Chem. 2002 Aug 09; 67(16):5673-7.
Cheng WC, Liu Y, Wong M, Olmstead MM, Lam KS, Kurth MJ. PMID: 12153267.
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PubMed Mentions: Fields:
Translation:
Cells
-
A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries. J Am Chem Soc. 2002 Jul 03; 124(26):7678-80.
Liu R, Marik J, Lam KS. PMID: 12083920.
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PubMed Mentions:
69 Fields:
Translation:
Cells
-
From combinatorial chemistry to chemical microarray. Curr Opin Chem Biol. 2002 Jun; 6(3):353-8.
Lam KS, Renil M. PMID: 12023117.
View in:
PubMed Mentions:
16 Fields:
-
An efficient approach to prepare glyoxylyl functionality on solid-support. Tetrahedron Letters. 2002 Jun 1; 43(25):4435-4437.
Xu XQ, Lam LK. .
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Publisher Site Mentions:
-
An unnatural amino acid that induces beta-sheet folding and interaction in peptides. J Am Chem Soc. 2002 May 08; 124(18):4972-3.
Nowick JS, Lam KS, Khasanova TV, Kemnitzer WE, Maitra S, Mee HT, Liu R. PMID: 11982357.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
-
Identifying peptide ligands for cell surface receptors using cell-growth-on-bead assay and one-bead one-compound combinatorial library. Biotechnology Letters. 2002 Mar 1; 24(6):497-500.
Lau LD, Guo GL, Liu LR, Song SA, Shao SC, Lam LK. .
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Publisher Site Mentions:
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Recognition of multiple substrate motifs by the c-ABL protein tyrosine kinase. Comb Chem High Throughput Screen. 2002 Feb; 5(1):83-91.
Wu JJ, Afar DE, Phan H, Witte ON, Lam KS. PMID: 11860343.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry. 2002 Jan 22; 41(3):861-8.
Nagy SR, Liu G, Lam KS, Denison MS. PMID: 11790108.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Therapeutic cancer targeting peptides. Biopolymers. 2002; 66(3):184-99.
Aina OH, Sroka TC, Chen ML, Lam KS. PMID: 12385037.
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PubMed Mentions:
83 Fields:
Translation:
HumansCells
-
Editorial: Peptides as cancer therapeutics. Biopolymers. 2002 Jan 1; 66(3):141-141.
Lam LK. .
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Publisher Site Mentions:
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Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis. J Immunol. 2001 Sep 01; 167(5):2956-63.
Long SA, Quan C, Van de Water J, Nantz MH, Kurth MJ, Barsky D, Colvin ME, Lam KS, Coppel RL, Ansari A, Gershwin ME. PMID: 11509645.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Automatic Edman microsequencing of peptides containing multiple unnatural amino acids. Anal Biochem. 2001 Aug 01; 295(1):9-16.
Liu R, Lam KS. PMID: 11476539.
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PubMed Mentions:
11 Fields:
Translation:
Cells
-
Peptide and small molecule microarray for high throughput cell adhesion and functional assays. Bioconjug Chem. 2001 May-Jun; 12(3):346-53.
Falsey JR, Renil M, Park S, Li S, Lam KS. PMID: 11353531.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
The use of one-bead one-compound combinatorial library method to identify peptide ligands for a4ß1 integrin receptor in non-Hodgkin's lymphoma. International Journal of Peptide Research and Therapeutics. 2001 May 1; 8(3-5):171-178.
Park PS, Renil RM, Vikstrom VB, Amro AN, Song SL, Xu XB, Lam LK. .
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Publisher Site Mentions:
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Synthetic peptides inhibit adhesion of human tumor cells to extracellular matrix proteins. Cancer Res. 2001 Apr 15; 61(8):3308-13.
DeRoock IB, Pennington ME, Sroka TC, Lam KS, Bowden GT, Bair EL, Cress AE. PMID: 11309285.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4403-8.
Miyashita M, Presley JM, Buchholz BA, Lam KS, Lee YM, Vogel JS, Hammock BD. PMID: 11287636; PMCID: PMC31847.
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PubMed Mentions:
11 Fields:
Translation:
Cells
-
Heterogeneous response of antimitochondrial autoantibodies and bile duct apical staining monoclonal antibodies to pyruvate dehydrogenase complex E2: the molecule versus the mimic. Hepatology. 2001 Apr; 33(4):792-801.
Migliaccio C, Van de Water J, Ansari AA, Kaplan MM, Coppel RL, Lam KS, Thompson RK, Stevenson F, Gershwin ME. PMID: 11283841.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment. J Clin Oncol. 2001 Mar 15; 19(6):1728-33.
Lara PN, Higdon R, Lim N, Kwan K, Tanaka M, Lau DH, Wun T, Welborn J, Meyers FJ, Christensen S, O'Donnell R, Richman C, Scudder SA, Tuscano J, Gandara DR, Lam KS. PMID: 11251003.
View in:
PubMed Mentions:
245 Fields:
Translation:
Humans
-
Development of inhibitors for protein tyrosine kinases. Oncogene. 2000 Nov 20; 19(49):5690-701.
Al-Obeidi FA, Lam KS. PMID: 11114749.
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PubMed Mentions:
23 Fields:
Translation:
Cells
-
Solution-phase synthesis of a 1,5-dialkylamino-2,4-dinitrobenzene library and the identification of novel antibacterial compounds from this library. J Comb Chem. 2000 Sep-Oct; 2(5):467-74.
Liu G, Fan Y, Carlson JR, Zhao ZG, Lam KS. PMID: 11029172.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Site-specific modification of a single-chain antibody using a novel glyoxylyl-based labeling reagent. Bioconjug Chem. 1999 May-Jun; 10(3):424-30.
Zhao ZG, Im JS, Lam KS, Lake DF. PMID: 10346874.
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PubMed Mentions:
7 Fields:
Translation:
Cells
-
Baculoviral expressed HLA class I heavy chains used to screen a synthetic peptide library for allele-specific peptide binding motifs. Mol Immunol. 1998 Nov; 35(16):1033-43.
Smith MH, Nuara AA, Egen JG, Sirjani DB, Lam KS, Grimes WJ. PMID: 10068038.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Comparison of the intrinsic kinase activity and substrate specificity of c-Abl and Bcr-Abl. Bioorg Med Chem Lett. 1998 Sep 08; 8(17):2279-84.
Wu JJ, Phan H, Lam KS. PMID: 9873528.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Discovery of a novel series of potent and selective substrate-based inhibitors of p60c-src protein tyrosine kinase: conformational and topographical constraints in peptide design. J Med Chem. 1998 Jun 18; 41(13):2252-60.
Alfaro-Lopez J, Yuan W, Phan BC, Kamath J, Lou Q, Lam KS, Hruby VJ. PMID: 9632358.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
A phase I/II trial of paclitaxel for non-Hodgkin's lymphoma followed by paclitaxel plus quinine in drug-resistant disease. Anticancer Drugs. 1998 Feb; 9(2):135-40.
Miller TP, Chase EM, Dorr R, Dalton WS, Lam KS, Salmon SE. PMID: 9510499.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Synthesis of a one-bead one-compound combinatorial peptide library. Methods Mol Biol. 1998; 87:1-6.
Lam KS, Lebl M. PMID: 9523253.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Determination of peptide substrate motifs for protein kinases using a "one-bead one-compound" combinatorial library approach. Methods Mol Biol. 1998; 87:83-6.
Lam KS. PMID: 9523262.
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PubMed Mentions: Fields:
Translation:
Cells
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Application of "one-bead one-compound" combinatorial library methods in signal transduction research. Life Sci. 1998; 62(17-18):1577-83.
Lam KS, Sroka T, Chen ML, Zhao Y, Lou Q, Wu J, Zhao ZG. PMID: 9585139.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Enzyme-linked colorimetric screening of a one-bead one-compound combinatorial library. Methods Mol Biol. 1998; 87:7-12.
Lam KS. PMID: 9523254.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Protein tyrosine kinases: structure, substrate specificity, and drug discovery. Biopolymers. 1998; 47(3):197-223.
al-Obeidi FA, Wu JJ, Lam KS. PMID: 9817025.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
-
Targeted therapy for lymphoma with peptides. Hematol Oncol Clin North Am. 1997 Oct; 11(5):1007-19.
Lam KS, Zhao ZG. PMID: 9336728.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Potent pseudosubstrate-based peptide inhibitors for p60(c-src) protein tyrosine kinase. Cancer Res. 1997 May 15; 57(10):1877-81.
Lou Q, Leftwich ME, McKay RT, Salmon SE, Rychetsky L, Lam KS. PMID: 9157979.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Application of combinatorial library methods in cancer research and drug discovery. Anticancer Drug Des. 1997 Apr; 12(3):145-67.
Lam KS. PMID: 9154108.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
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The "One-Bead-One-Compound" Combinatorial Library Method. Chem Rev. 1997 Apr 01; 97(2):411-448.
Lam KS, Lebl M, Krchnák V. PMID: 11848877.
View in:
PubMed Mentions:
147 Fields:
-
The use of a combinatorial library method to isolate human tumor cell adhesion peptides. Mol Divers. 1996 Oct; 2(1-2):19-28.
Pennington ME, Lam KS, Cress AE. PMID: 9238629.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
High-volume cellular screening for anticancer agents with combinatorial chemical libraries: a new methodology. Mol Divers. 1996 Oct; 2(1-2):57-63.
Salmon SE, Liu-Stevens RH, Zhao Y, Lebl M, Krchñák V, Wertman K, Sepetov N, Lam KS. PMID: 9238634.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Design considerations and computer modeling related to the development of molecular scaffolds and peptide mimetics for combinatorial chemistry. Mol Divers. 1996 Oct; 2(1-2):46-56.
Hruby VJ, Shenderovich M, Lam KS, Lebl M. PMID: 9238633.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Enzyme-mediated spatial segregation on individual polymeric support beads: application to generation and screening of encoded combinatorial libraries. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8194-9.
Vágner J, Barany G, Lam KS, Krchnák V, Sepetov NF, Ostrem JA, Strop P, Lebl M. PMID: 8710846; PMCID: PMC38645.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
Combinatorial Library Based on the One-Bead-One-Compound Concept. . 1996 Jun 27; 173-201.
Lam LK, Lebl LM. .
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Publisher Site Mentions:
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A One-Bead One-Peptide Combinatorial Library Method for B-Cell Epitope Mapping Methods. 1996 Jun; 9(3):482-93.
Lam KS, Lake D, Salmon SE, Smith J, Chen ML, Wade S, Abdul-Latif F, Knapp RJ, Leblova Z, Ferguson RD, Krchnak V, Sepetov NF, Lebl M. PMID: 8812704.
View in:
PubMed Mentions:
12 Fields:
-
Bifunctional scaffolds as templates for synthetic combinatorial libraries. Mol Divers. 1996 May; 1(3):177-82.
Krchnák V, Weichsel AS, Issakova O, Lam KS, Lebl M. PMID: 9237208.
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PubMed Mentions:
3 Fields:
Translation:
Cells
-
Identification of GIYWHHY as a novel peptide substrate for human p60c-src protein tyrosine kinase. Bioorg Med Chem. 1996 May; 4(5):677-82.
Lou Q, Leftwich ME, Lam KS. PMID: 8804533.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
A protein kinase assay system for both acidic and basic peptides. Anal Biochem. 1996 Mar 01; 235(1):107-9.
Lou Q, Wu J, Lam KS. PMID: 8850556.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
One bead-one compound combinatorial peptide library: different types of screening. Methods Enzymol. 1996; 267:211-9.
Chen CL, Strop P, Lebl M, Lam KS. PMID: 8743318.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Structure-activity relationship of a novel peptide substrate for p60c-src protein tyrosine kinase. International Journal of Peptide Research and Therapeutics. 1996 Jan 1; 2(5):289-296.
Lou LQ, Wu WJ, Salmon SS, Lam LK. .
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Publisher Site Mentions:
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Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs. Proc Natl Acad Sci U S A. 1995 Jun 06; 92(12):5426-30.
Sepetov NF, Krchnák V, Stanková M, Wade S, Lam KS, Lebl M. PMID: 7777524; PMCID: PMC41707.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. Int J Pept Protein Res. 1995 Jun; 45(6):587-92.
Lam KS, Wu J, Lou Q. PMID: 7558590.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Application of a dual color detection scheme in the screening of a random combinatorial peptide library. J Immunol Methods. 1995 Mar 27; 180(2):219-23.
Lam KS, Wade S, Abdul-Latif F, Lebl M. PMID: 7714336.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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Idiotype specific peptides bind to the surface immunoglobulins of two murine B-cell lymphoma lines, inducing signal transduction. Biomed Pept Proteins Nucleic Acids. 1995; 1(3):205-10.
Lam KS, Lou Q, Zhao ZG, Smith J, Chen ML, Pleshko E, Salmon SE. PMID: 9346854.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
One-bead-one-structure combinatorial libraries. Biopolymers. 1995; 37(3):177-98.
Lebl M, Krchnák V, Sepetov NF, Seligmann B, Strop P, Felder S, Lam KS. PMID: 7718741.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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A novel approach for iodolabelling synthetic peptides. Chemical Communications. 1995 Jan 1; 0(17):1739-1740.
Zhao ZZ, Lam LK. .
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Publisher Site Mentions:
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Use of Large Combinatorial Chemical Libraries for Anticancer Drug Discovery. Pharmaceutical Biology. 1995 Jan 1; 33(s1):67-74.
Salmon SS, Lam LK, Felder FS, Yeoman YH, Schlessinger SJ, Ullrich UA, Krchnak KV, Lebl LM. .
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Identifying substrate motifs of protein kinases by a random library approach. Biochemistry. 1994 Dec 13; 33(49):14825-33.
Wu J, Ma QN, Lam KS. PMID: 7993909.
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18 Fields:
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Cells
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Peptide sequences binding to MHC class I proteins. Mol Immunol. 1994 Dec; 31(18):1431-7.
Smith MH, Lam KS, Hersh EM, Lebl M, Grimes WJ. PMID: 7823969.
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2 Fields:
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HumansCells
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Screening of Completely Random One-Bead One-Peptide Libraries for Activities in Solution. Methods. 1994 Dec 1; 6(4):381-387.
Lebl LM, Krchnák KV, Salmon SS, Lam LK. .
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Selectide Technology: Bead-Binding Screening. Methods. 1994 Dec 1; 6(4):372-380.
Lam LK, Lebl LM. .
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Selectide Technology: Substrate Motif Identification for Post-translational Modifications. Methods. 1994 Dec 1; 6(4):401-403.
Lam LK, Wu WJ. .
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Synthesis of combinatorial libraries with only one representation of each structure. Pept Res. 1994 Nov-Dec; 7(6):292-8.
Stanková M, Wade S, Lam KS, Lebl M. PMID: 7888712.
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1 Fields:
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AnimalsCells
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Application of one-bead one-structure approach to identification of nonpeptidic ligands. Drug Development Research. 1994 Oct 1; 33(2):146-156.
Stanková SM, Issakova IO, Sepetov SN, Krchnák KV, Lam LK, Lebl LM. .
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Identification of small peptides that interact specifically with a small organic dye. Drug Development Research. 1994 Oct 1; 33(2):157-160.
Lam LK, Zhao ZZ, Wade WS, Krchnák KV, Lebl LM. .
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Molecular cloning, expression and mutagenesis of an anti-insulin single chain Fv (scFv). Mol Immunol. 1994 Aug; 31(11):845-56.
Lake DF, Lam KS, Peng L, Hersh EM. PMID: 8047074.
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3 Fields:
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Cells
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MPSA short communications. The Protein Journal. 1994 Jul 1; 13(5):431-512.
Barnes BE, Calkin CP, Kuroda KS, Norioka NS, Mitta MM, Kato KI, Sakiyama SF, Nika NH, Chow CD, Hess HD, Bures BE, Morrison MH, Aebersold AR, Clore CG, Gronenborn GA, Persson PB, Argos AP, James JP, Cannons CA, Solomonson SL, Dombrowski DK, Moddeman MW, Wright WS, Barker BW, George GD, Mattagajasingh MS, Misra MH, Huang HS, Huang HJ, Lee LY, Fischer FW, Craig CA, McFadden MP, Lind-quist LJ, Bartlet-Jones BM, Jeffery JW, Hansen HH, Pappin PD, Bergman BT, Hjelmqvist HL, Estonius EM, Jörnvall JH, Dorow DD, Tschesche TH, Knäuper KV, Kleine KT, Reinemer RP, Schnierer SS, Grams GF, Bode BW, Southan SC, Fantom FK, Lavery LP, Findlay FJ, Akrigg AD, Attwood AT, Beck BM, Bleasby BA, North NA, Parry-Smith PD, Perkins PD, Aitken AA, Patel PY, Martin MH, Jones JD, Robinson RK, Madrazo MJ, Howell HS, Aebersold AR, Hess HD, Yungwirth YT, Affolter AM, Amankwa AL, Hess HD, Aebersold AR, Scheraga SH, Yang YC, Valentinova VN, Yang YM, Gu GZ, Gotto GA, Dovichi DN, Waldron WK, Chen CM, Ireland II, Omori OA, Yoshida YS, Schaller SJ, Lengweiler LS, Rickli RE, Bubis BJ, Ortiz OJ, Möller MC, Millán ME, Boyd BV, Bozzini BM, Zhao ZJ, DeFranco DR, Yuan YP, Loudon LG, Nguyen ND, Kamo KM, Kawakami KT, Miyatake MN, Tsugita TA, Tsugita TA, Kamo KM, Takamoto TK, Satake SK, Bischof BO, Hechenberger HM, Thiede TB, Kruft KV, Wittmann-Liebold WB, Otto OA, Benndorf BR, Wittmann-Liebold WB, Jungblut JP, Ühlein ÜM, Wittmann-Liebold WB, Urlaub UH, Kruft KV, Wittmann-Liebold WB, Berhardt BR, Kraft KR, Uhlmann UH, Beckert BV, Akizawa AT, Ayabe AT, Matsukawa MM, Itoh IM, Nishi NM, Sato SH, Seiki SM, Yoshioka YM, Lebl LM, Krchnák KV, Sepetov SN, Kociš KP, Pátek PM, Flegelová FZ, Ferguson FR, Lam LK, Moritz MR, Eddes EJ, Ji JH, Reid RG, Simpson SR, Seffens SW, Poulter PC, Dolence DJ, Bond BP, Nokihara NK, Ikegaya IK, Morita MN, Ohmura OT, Salikhov SS, Sagdiev SN, Korneev KA, Dolimbek DB, Atassi AM, Rosenberg RJ, Yun YZ, Wyde WP, Atassi AM, Gaskell GS, Anumula AK, Goldenberg GD, Appella AE, Fiscella FM, Zambrano ZN, Ullrich US, Sakaguchi SK, Sakamoto SH, Lewis LM, Lin LD, Mercer MW, Anderson AC, Anderson AC, Connelly CM, Zhang ZH, Sipley SJ, Lees-Miller LS, Sakaguchi SK, Ullrich US, Jackson JS, Appella AE, Xie XY, Yang YM, Quion QJ, Gotto GA, Yang YC, Brandt BW, Alk AH, Bhaskaran BR, Yu YC, Yang YC, Henschen HA, Ashman AK, Mann MM, Guevara GJ, Nguyen NH, Davison DD, Morrisett MJ, Perham PR, Marvin MD, Symmons SM, Terry TT, Beg BZ, Stonik SJ, Hoeg HJ, Brewer BH, Gorovits GB, Raman RC, Horowtiz HP. .
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Construction and Screening of Libraries of Peptide and Non-Peptide Structures. . 1994 Jan 1; 5:541-548.
Lebl LM, Krchnák KV, Šafár ŠP, Stierandová SA, Sepetov SN, Kociš KP, Lam LK. .
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One bead, one chemical compound: use of the selectide process for anticancer drug discovery. Acta Oncol. 1994; 33(2):127-31.
Salmon SE, Lam KS, Felder S, Yeoman H, Schlessinger J, Ullrich A, Krchnák V, Lebl M. PMID: 7911310.
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PubMed Mentions:
2 Fields:
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HumansCells
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Discovery of D-amino-acid-containing ligands with selectide technology. Gene. 1993 Dec 27; 137(1):13-6.
Lam KS, Lebl M, Krchnak V, Wade S, Abdul-Latif F, Ferguson R, Cuzzocrea C, Wertman K. PMID: 8282196.
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3 Fields:
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AnimalsCells
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Discovery of biologically active peptides in random libraries: solution-phase testing after staged orthogonal release from resin beads. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11708-12.
Salmon SE, Lam KS, Lebl M, Kandola A, Khattri PS, Wade S, Pátek M, Kocis P, Krchnák V, Thorpe D, et al. PMID: 8265613; PMCID: PMC48053.
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12 Fields:
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HumansCells
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Treatment of B-cell lymphoma using peptides. A novel concept. West J Med. 1993 May; 158(5):475-9.
Lam KS. PMID: 8342262; PMCID: PMC1022127.
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2 Fields:
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HumansCells
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Peptide-encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports. Pept Res. 1993 May-Jun; 6(3):161-70.
Nikolaiev V, Stierandová A, Krchnák V, Seligmann B, Lam KS, Salmon SE, Lebl M. PMID: 8318748.
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15 Fields:
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Cells
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The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors. Bioorganic & Medicinal Chemistry Letters. 1993 Mar 1; 3(3):419-424.
Lam LK, Hruby HV, Lebl LM, Knapp KR, Kazmierski KW, Hersh HE, Salmon SS. .
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Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage-cleavage chemistry. Int J Pept Protein Res. 1993 Feb; 41(2):201-3.
Lebl M, Pátek M, Kocis P, Krchnák V, Hruby VJ, Salmon SE, Lam KS. PMID: 8458693.
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10 Fields:
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Cells
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Preparation of large peptide libraries with one peptide per bead and their use for the discovery of peptides that bind to acceptors. NIDA Res Monogr. 1993; 134:75-83.
Hruby VJ, Lam KS, Lebl M, Kazmierski W, Hersh EM, Salmon SE. PMID: 8289888.
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Streptavidin and avidin recognize peptide ligands with different motifs. Methods. 1992 Aug 1; 1(1):11-15.
Lam LK, Lebl LM. .
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Phase I and pharmacokinetic study of 502U83 (an arylmethylaminopropanediol) in cancer patients. Anticancer Drugs. 1992 Jun; 3(3):219-24.
Lam KS, Alberts DS, Peng YM, Brodar F, Matias B, Modiano M, Tuttle R, Sol Lucas V, Wargin W. PMID: 1525401.
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Humans
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A new type of synthetic peptide library for identifying ligand-binding activity. Nature. 1991 Nov 07; 354(6348):82-4.
Lam KS, Salmon SE, Hersh EM, Hruby VJ, Kazmierski WM, Knapp RJ. PMID: 1944576.
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392 Fields:
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Cells
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Ability of cell-sized beads bearing tumor cell membrane proteins to stimulate LAK cells to secrete interferon-gamma and tumor necrosis factor-alpha. Cell Immunol. 1991 Apr 15; 134(1):96-110.
Chong AS, Pinkard JK, Lam KS, Scuderi P, Hersh EM, Grimes WJ. PMID: 1901521.
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HumansCells
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Idiotypic variation in a human B lymphoma cell line. J Immunol. 1990 Jan 15; 144(2):752-8.
Berinstein N, Campbell MJ, Lam K, Carswell C, Levy S, Levy R. PMID: 2295809.
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1 Fields:
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HumansCells
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Analysis of the molecular organization of recombinant human tumor necrosis factor (rTNF) in solution using ethylene glycolbis(succinimidylsuccinate) as the cross-linking reagent. J Biol Response Mod. 1988 Jun; 7(3):267-75.
Lam KS, Scuderi P, Salmon SE. PMID: 3392553.
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5 Fields:
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Raised serum levels of tumour necrosis factor in parasitic infections. Lancet. 1986 Dec 13; 2(8520):1364-5.
Scuderi P, Sterling KE, Lam KS, Finley PR, Ryan KJ, Ray CG, Petersen E, Slymen DJ, Salmon SE. PMID: 2878227.
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PubMed Mentions:
80 Fields:
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Humans
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Construction and testing of mouse--human heteromyelomas for human monoclonal antibody production. Proc Natl Acad Sci U S A. 1983 Dec; 80(23):7308-12.
Teng NN, Lam KS, Calvo Riera F, Kaplan HS. PMID: 6316357; PMCID: PMC390044.
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42 Fields:
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HumansAnimalsCells
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Comparative studies on the endogenous phosphorylation of microsomal membrane derived from Morris hepatoma, eight-day-old rats, and host livers in the presence of micromolar levels of Mg2+ ion. Cancer Res. 1981 Mar; 41(3):860-3.
Lam KS, Kasper CB. PMID: 7459872.
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AnimalsCells
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Chemical synthesis of [32P]pyrophosphate with high specific activity. Anal Biochem. 1980 Nov 01; 108(2):279-81.
Lam KS, Kasper CB. PMID: 6257141.
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Sequence homology analysis of a heterogenous protein population by chemical and enzymic digestion using a two-dimensional sodium dodecyl sulfate-polyacrylamide gel system. Anal Biochem. 1980 Nov 01; 108(2):220-6.
Lam KS, Kasper CB. PMID: 6779669.
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7 Fields:
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Cells
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Pyrophosphate:protein phosphotransferase: a membrane-bound enzyme of endoplasmic reticulum. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):1927-31.
Lam KS, Kasper CB. PMID: 6246514; PMCID: PMC348622.
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AnimalsCells
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Selective endogenous phosphorylation of two liver microsomal polypeptides in the presence of micromolar levels of Mg2+ ion. J Biol Chem. 1980 Jan 10; 255(1):259-66.
Lam KS, Kasper CB. PMID: 7350158.
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4 Fields:
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AnimalsCells
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Electrophoretic analysis of three major nuclear envelope polypeptides. Topological relationship and sequence homology. J Biol Chem. 1979 Nov 25; 254(22):11713-20.
Lam KS, Kasper CB. PMID: 500669.
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13 Fields:
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AnimalsCells
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Selective phosphorylation of a nuclear envelope polypeptide by an endogenous protein kinase. Biochemistry. 1979 Jan 23; 18(2):307-11.
Lam KS, Kasper CB. PMID: 217409.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells