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Multifunctional and Scalable Nanoparticles for Bimodal Image-Guided Phototherapy in Bladder Cancer Treatment. Nanomicro Lett. 2025 Apr 18; 17(1):222.
Tang M, Mahri S, Shiau YP, Mukarrama T, Villa R, Zong Q, Racacho KJ, Li Y, Lee Y, Huang Y, Cong Z, Kim J, Li Y, Lin TY. PMID: 40249569; PMCID: PMC12008111.
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PubMed Mentions:
3
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Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy. Small Sci. 2025 Jun; 5(6):2400607.
Mahri S, Villa R, Shiau YP, Tang M, Racacho KJ, Zong Q, Chowdhury SI, Hua T, Godinez F, Birkeland A, Lin TY, Li Y. PMID: 40529859; PMCID: PMC12168626.
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PubMed Mentions:
5
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Design, structure-activity relationships, and enzyme kinetic studies of tricyclic and tetracyclic coumarin-based sulfamates as steroid sulfatase inhibitors. Bioorg Chem. 2023 09; 138:106581.
Chiu PF, Lin IC, Lu YL, Chang CN, Chan HY, Lin TS, Tsai KC, Hsieh YSY, Chen MJ, Lin MH, Liang PH. PMID: 37172437.
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PubMed Mentions: Fields:
Translation:
Humans
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Programmed-response cross-linked nanocarrier for multidrug-resistant ovarian cancer treatment. J Control Release. 2023 05; 357:274-286.
Qu H, Yang J, Li S, Xu J, Zhou X, Xue X, Zhang D, Du H, Shen Y, Ramachandran M, Zheng H, Wu Y, Ding Y, Wu H, Ma X, Lin TY, Li Y. PMID: 36958401.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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The Design, Structure-Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors. Bioorg Chem. 2022 Dec; 129:106148.
Chang CN, Lin IC, Lin TS, Chiu PF, Lu YL, Narwane M, Liu IC, Hng Y, Tsai KC, Lin MH, S Y Hsieh Y, Chen MJ, Liang PH. PMID: 36244324.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Targeting Colorectal Cancer with Conjugates of a Glucose Transporter Inhibitor and 5-Fluorouracil. J Med Chem. 2021 04 22; 64(8):4450-4461.
Chang CK, Chiu PF, Yang HY, Juang YP, Lai YH, Lin TS, Hsu LC, Yu LC, Liang PH. PMID: 33819035.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Excipient-free porphyrin/SN-38 based nanotheranostics for drug delivery and cell imaging. Nano Research. 2020 Feb 1; 13(2):503-510.
Yuan YY, Bo BR, Jing JD, Ma MZ, Wang WZ, Lin LT, Dong DL, Xue XX, Li LY. .
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Design and synthesis of 3-benzylaminocoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors. Bioorg Chem. 2020 03; 96:103618.
Hng Y, Lin MH, Lin TS, Liu IC, Lin IC, Lu YL, Chang CN, Chiu PF, Tsai KC, Chen MJ, Liang PH. PMID: 32059152.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Sulfation pattern of chondroitin sulfate in human osteoarthritis cartilages reveals a lower level of chondroitin-4-sulfate. Carbohydr Polym. 2020 Feb 01; 229:115496.
Lin TS, Hsieh CH, Kuo C, Juang YP, Hsieh YSY, Chiang H, Hung SC, Jiang CC, Liang PH. PMID: 31826425.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Peptide-based materials for cancer immunotherapy. Theranostics. 2019; 9(25):7807-7825.
Zhang L, Huang Y, Lindstrom AR, Lin TY, Lam KS, Li Y. PMID: 31695802; PMCID: PMC6831480.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia. Nanomedicine. 2019 08; 20:102004.
Lin TY, Zhu Y, Li Y, Zhang H, Ma AH, Long Q, Keck J, Lam KS, Pan CX, Jonas BA. PMID: 31055076; PMCID: PMC8237247.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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A facile approach to fabricate self-assembled magnetic nanotheranostics for drug delivery and imaging. Nanoscale. 2018 Nov 29; 10(46):21634-21639.
Yuan Y, He Y, Bo R, Ma Z, Wang Z, Dong L, Lin TY, Xue X, Li Y. PMID: 30457141; PMCID: PMC6317527.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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A polymer-free, biomimicry drug self-delivery system fabricated via a synergistic combination of bottom-up and top-down approaches. J Mater Chem B. 2018 12 21; 6(47):7842-7853.
Xu X, Yang G, Xue X, Lu H, Wu H, Huang Y, Jing D, Xiao W, Tian J, Yao W, Pan CX, Lin TY, Li Y. PMID: 31380107; PMCID: PMC6676892.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Trojan Horse nanotheranostics with dual transformability and multifunctionality for highly effective cancer treatment. Nat Commun. 2018 09 07; 9(1):3653.
Xue X, Huang Y, Bo R, Jia B, Wu H, Yuan Y, Wang Z, Ma Z, Jing D, Xu X, Yu W, Lin TY, Li Y. PMID: 30194413; PMCID: PMC6128896.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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A highly integrated precision nanomedicine strategy to target esophageal squamous cell cancer molecularly and physically. Nanomedicine. 2018 10; 14(7):2103-2114.
Wang XS, Ding XZ, Li XC, He Y, Kong DJ, Zhang L, Hu XC, Yang JQ, Zhao MQ, Gao SG, Lin TY, Li Y. PMID: 30047470; PMCID: PMC6648684.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy. Adv Funct Mater. 2018 Aug 15; 28(33).
Wang Z, Xue X, He Y, Lu Z, Jia B, Wu H, Yuan Y, Huang Y, Wang H, Lu H, Lam KS, Lin TY, Li Y. PMID: 31303869; PMCID: PMC6625784.
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PubMed Mentions:
7
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Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo. Nanomedicine (Lond). 2018 05; 13(10):1107-1120.
Wang XS, Zhang L, Li X, Kong DJ, Hu XC, Ding XZ, Yang JQ, Zhao MQ, He Y, Lam KS, Gao SG, Lin TY, Li Y. PMID: 29874151; PMCID: PMC6219431.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy. Biomaterials. 2018 04; 161:203-215.
Xue X, Huang Y, Wang X, Wang Z, Carney RP, Li X, Yuan Y, He Y, Lin TY, Li Y. PMID: 29421556; PMCID: PMC5846343.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model. Nanomedicine. 2018 04; 14(3):789-799.
Long Q, Lin TY, Huang Y, Li X, Ma AH, Zhang H, Carney R, Airhart S, Lam KS, deVere White RW, Pan CX, Li Y. PMID: 29317342; PMCID: PMC5898975.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. Mol Cancer Ther. 2018 02; 17(2):474-483.
Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, de Vere White RW, Pan CX. PMID: 29284644; PMCID: PMC5824635.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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"One-Pot" Fabrication of Highly Versatile and Biocompatible Poly(vinyl alcohol)-porphyrin-based Nanotheranostics. Theranostics. 2017; 7(16):3901-3914.
Luo Y, Wu H, Feng C, Xiao K, Yang X, Liu Q, Lin TY, Zhang H, Walton JH, Ajena Y, Hu Y, Lam KS, Li Y. PMID: 29109786; PMCID: PMC5667413.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer. J Control Release. 2017 Oct 28; 264:169-179.
Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y. PMID: 28847739; PMCID: PMC5632596.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer. Clin Cancer Res. 2017 Nov 01; 23(21):6580-6591.
Zeng SX, Zhu Y, Ma AH, Yu W, Zhang H, Lin TY, Shi W, Tepper CG, Henderson PT, Airhart S, Guo JM, Xu CL, deVere White RW, Pan CX. PMID: 28808038; PMCID: PMC5668181.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Sub-100nm, long tumor retention SN-38-loaded photonic micelles for tri-modal cancer therapy. J Control Release. 2017 09 10; 261:297-306.
Yang X, Xue X, Luo Y, Lin TY, Zhang H, Lac D, Xiao K, He Y, Jia B, Lam KS, Li Y. PMID: 28700898; PMCID: PMC5589441.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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A facile strategy for fine-tuning the stability and drug release of stimuli-responsive cross-linked micellar nanoparticles towards precision drug delivery. Nanoscale. 2017 Jun 14; 9(23):7765-7770.
Xiao K, Lin TY, Lam KS, Li Y. PMID: 28585953; PMCID: PMC5568647.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer. Acta Pharmacol Sin. 2017 Jun; 38(6):931-942.
Wang XS, Kong DJ, Lin TY, Li XC, Izumiya Y, Ding XZ, Zhang L, Hu XC, Yang JQ, Gao SG, Lam KS, Li YP. PMID: 28552907; PMCID: PMC5520194.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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A diagnostic microdosing approach to investigate platinum sensitivity in non-small cell lung cancer. Int J Cancer. 2017 08 01; 141(3):604-613.
Wang SS, Zimmermann M, Zhang H, Lin TY, Malfatti M, Haack K, Turteltaub KW, Cimino GD, de Vere White R, Pan CX, Henderson PT. PMID: 28437852; PMCID: PMC5497716.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Microdose-Induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice. Mol Cancer Ther. 2017 02; 16(2):376-387.
Zimmermann M, Wang SS, Zhang H, Lin TY, Malfatti M, Haack K, Ognibene T, Yang H, Airhart S, Turteltaub KW, Cimino GD, Tepper CG, Drakaki A, Chamie K, de Vere White R, Pan CX, Henderson PT. PMID: 27903751; PMCID: PMC5335870.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Disulfide-crosslinked nanomicelles confer cancer-specific drug delivery and improve efficacy of paclitaxel in bladder cancer. Nanotechnology. 2016 Oct 21; 27(42):425103.
Pan A, Zhang H, Li Y, Lin TY, Wang F, Lee J, Cheng M, Dall'Era M, Li T, deVere White R, Pan CX, Lam KS. PMID: 27640312; PMCID: PMC6522262.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer. Biomaterials. 2016 10; 104:339-51.
Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX. PMID: 27479049; PMCID: PMC5412594.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy. Theranostics. 2016; 6(9):1324-35.
Lin TY, Guo W, Long Q, Ma A, Liu Q, Zhang H, Huang Y, Chandrasekaran S, Pan C, Lam KS, Li Y. PMID: 27375782; PMCID: PMC4924502.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer. PLoS One. 2016; 11(1):e0146256.
Wang S, Zhang H, Scharadin TM, Zimmermann M, Hu B, Pan AW, Vinall R, Lin TY, Cimino G, Chain P, Vuyisich M, Gleasner C, Mcmurry K, Malfatti M, Turteltaub K, de Vere White R, Pan CX, Henderson PT. PMID: 26799320; PMCID: PMC4723083.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Paclitaxel Enhances Carboplatin-DNA Adduct Formation and Cytotoxicity. Chem Res Toxicol. 2015 Dec 21; 28(12):2250-2.
Jiang S, Pan AW, Lin TY, Zhang H, Malfatti M, Turteltaub K, Henderson PT, Pan CX. PMID: 26544157; PMCID: PMC4834887.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Smart and Fast Blood Counting of Trace Volumes of Body Fluids from Various Mammalian Species Using a Compact, Custom-Built Microscope Cytometer. Anal Chem. 2015 Dec 01; 87(23):11854-62.
Gao T, Smith ZJ, Lin TY, Carrade Holt D, Lane SM, Matthews DL, Dwyre DM, Hood J, Wachsmann-Hogiu S. PMID: 26496235.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy. PLoS One. 2015; 10(8):e0134346.
Pan CX, Zhang H, Tepper CG, Lin TY, Davis RR, Keck J, Ghosh PM, Gill P, Airhart S, Bult C, Gandara DR, Liu E, de Vere White RW. PMID: 26270481; PMCID: PMC4535951.
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Nanomedicine in veterinary oncology. Vet J. 2015 Aug; 205(2):189-97.
Lin TY, Rodriguez CO, Li Y. PMID: 25862394.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Nanotechnology in bladder cancer: current state of development and clinical practice. Nanomedicine (Lond). 2015; 10(7):1189-201.
Tomlinson B, Lin TY, Dall'Era M, Pan CX. PMID: 25929573; PMCID: PMC4562431.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Urethral reconstruction with tissue-engineered human amniotic scaffold in rabbit urethral injury models. Med Sci Monit. 2014 Nov 26; 20:2430-8.
Wang F, Liu T, Yang L, Zhang G, Liu H, Yi X, Yang X, Lin TY, Qin W, Yuan J. PMID: 25424000; PMCID: PMC4257484.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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A smart and versatile theranostic nanomedicine platform based on nanoporphyrin. Nat Commun. 2014 Aug 26; 5:4712.
Li Y, Lin TY, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, Lam KS. PMID: 25158161; PMCID: PMC4145614.
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PubMed Mentions:
131 Fields:
Translation:
HumansAnimalsCells
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Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014; 9(12):1807-20.
Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, Pan CX. PMID: 24628688; PMCID: PMC4167557.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Overexpression of miR-9 in mast cells is associated with invasive behavior and spontaneous metastasis. BMC Cancer. 2014 Feb 11; 14:84.
Fenger JM, Bear MD, Volinia S, Lin TY, Harrington BK, London CA, Kisseberth WC. PMID: 24517413; PMCID: PMC3933481.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer. Nanomedicine (Lond). 2013 Aug; 8(8):1239-51.
Lin TY, Li YP, Zhang H, Luo J, Goodwin N, Gao T, White Rde V, Lam KS, Pan CX. PMID: 23199207; PMCID: PMC3664656.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. Int J Nanomedicine. 2012; 7:2793-804.
Lin TY, Zhang H, Luo J, Li Y, Gao T, Lara PN, de Vere White R, Lam KS, Pan CX. PMID: 22745542; PMCID: PMC3383352.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Targeting canine bladder transitional cell carcinoma with a human bladder cancer-specific ligand. Mol Cancer. 2011 Jan 27; 10(1):9.
Lin TY, Zhang H, Wang S, Xie L, Li B, Rodriguez CO, de Vere White R, Pan CX. PMID: 21272294; PMCID: PMC3040722.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Mast cell tumors in a llama (Lama glama). J Vet Diagn Invest. 2010 Sep; 22(5):808-11.
Lin TY, Hamberg A, Pentecost R, Wellman M, Stromberg P. PMID: 20807950.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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What is your diagnosis? Fine-needle aspirate of an aggressive bone lesion in a dog. Chondrosarcoma. Vet Clin Pathol. 2010 Sep; 39(3):397-8.
Lin TY, Hosoya K, Drost WT, Premanandan C, Wellman M. PMID: 20561319.
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PubMed Mentions: Fields:
Translation:
Animals
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AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood. 2010 May 27; 115(21):4217-25.
Lin TY, Fenger J, Murahari S, Bear MD, Kulp SK, Wang D, Chen CS, Kisseberth WC, London CA. PMID: 20233974; PMCID: PMC3398750.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Characterization and modulation of canine mast cell derived eicosanoids. Vet Immunol Immunopathol. 2010 May 15; 135(1-2):118-127.
Lin TY, London CA. PMID: 20036014; PMCID: PMC3807043.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Generation and characterization of novel canine malignant mast cell line CL1. Vet Immunol Immunopathol. 2009 Jan 15; 127(1-2):114-24.
Lin TY, Thomas R, Tsai PC, Breen M, London CA. PMID: 19054577; PMCID: PMC3743436.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors. Exp Hematol. 2008 Oct; 36(10):1266-77.
Lin TY, Bear M, Du Z, Foley KP, Ying W, Barsoum J, London C. PMID: 18657349; PMCID: PMC3837096.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet Immunol Immunopathol. 2006 Dec 15; 114(3-4):320-34.
Lin TY, London CA. PMID: 17027994.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Generation and characterization of bone marrow-derived cultured canine mast cells. Vet Immunol Immunopathol. 2006 Sep 15; 113(1-2):37-52.
Lin TY, Rush LJ, London CA. PMID: 16780961.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells