Wenwu Xiao

Title(s)Clinical Lab Scientist, Microbiology Laboratory
SchoolUC Davis Health
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    1. Simvastatin Overcomes Resistance to Tyrosine Kinase Inhibitors in Patient-derived, Oncogene-driven Lung Adenocarcinoma Models. Mol Cancer Ther. 2024 May 02; 23(5):700-710. Ma W, Wei S, Li Q, Zeng J, Xiao W, Zhou C, Yoneda KY, Zeki AA, Li T. PMID: 38237027; PMCID: PMC11065592.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Site-Specific Albumin-Selective Ligation to Human Serum Albumin under Physiological Conditions. Bioconjug Chem. 2022 12 21; 33(12):2332-2340. Yu X, Ruan M, Wang Y, Nguyen A, Xiao W, Ajena Y, Solano LN, Liu R, Lam KS. PMID: 36350013; PMCID: PMC9782315.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect. Biomaterials. 2022 10; 289:121769. Jing D, Jiang N, Wang F, Mao C, Han S, Ho PY, Xiao W, Li Y, Li JJ, Zhang L, Lam KS. PMID: 36084485; PMCID: PMC10021813.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Programmable Bispecific Nano-immunoengager That Captures T Cells and Reprograms Tumor Microenvironment. Nano Lett. 2022 09 14; 22(17):6866-6876. Zhang L, Bo R, Wu Y, Li L, Zhu Z, Ma AH, Xiao W, Huang Y, Rojalin T, Yin X, Mao C, Wang F, Wang Y, Zhang H, Low KE, Lee K, Ajena Y, Jing D, Zhang D, Baehr CM, Liu R, Wang L, Li Y, Lam KS. PMID: 35926215; PMCID: PMC9479133.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    5. Discovery and Characterization of a Potent Antifungal Peptide through One-Bead, One-Compound Combinatorial Library Screening. ACS Infect Dis. 2022 07 08; 8(7):1291-1302. Bansal S, Vu K, Liu R, Ajena Y, Xiao W, Menon SM, Bennett A, Gelli A, Lam KS. PMID: 35700987.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    6. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511. Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    7. Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent. RSC Adv. 2022 Mar 08; 12(13):7742-7756. Zhou J, Meli VS, Yu-Tin Chen E, Kapre R, Nagalla R, Xiao W, Borowsky AD, Lam KS, Liu WF, Louie AY. PMID: 35424752; PMCID: PMC8982161.
      View in: PubMed   Mentions: 7  
    8. Effect of the p53 P72R Polymorphism on Mutant TP53 Allele Selection in Human Cancer. J Natl Cancer Inst. 2021 09 04; 113(9):1246-1257. De Souza C, Madden J, Koestler DC, Minn D, Montoya DJ, Minn K, Raetz AG, Zhu Z, Xiao WW, Tahmassebi N, Kathi HR, Nelson N, Karnezis AN, Chien J. PMID: 33555293; PMCID: PMC8633460.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    9. Transformable amyloid-beta mimetic peptide amphiphiles for lysosomal disruption in non-small cell lung cancer. Biomaterials. 2021 10; 277:121078. Baehr CM, Zhang L, Wu Y, Domokos A, Xiao W, Wang L, Lam KS. PMID: 34461458; PMCID: PMC9969961.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Tumor Receptor-Mediated In Vivo Modulation of the Morphology, Phototherapeutic Properties, and Pharmacokinetics of Smart Nanomaterials. ACS Nano. 2021 01 26; 15(1):468-479. Zhang L, Wu Y, Yin X, Zhu Z, Rojalin T, Xiao W, Zhang D, Huang Y, Li L, Baehr CM, Yu X, Ajena Y, Li Y, Wang L, Lam KS. PMID: 33332957.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    11. The P72R Polymorphism in R248Q/W p53 Mutants Modifies the Mutant Effect on Epithelial to Mesenchymal Transition Phenotype and Cell Invasion via CXCL1 Expression. Int J Mol Sci. 2020 Oct 28; 21(21). De Souza C, Madden JA, Minn D, Kumar VE, Montoya DJ, Nambiar R, Zhu Z, Xiao WW, Tahmassebi N, Kathi H, Nelson N, Karnezis AN, Chien J. PMID: 33126568; PMCID: PMC7662892.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    12. Identification of osteogenic progenitor cell-targeted peptides that augment bone formation. Nat Commun. 2020 08 27; 11(1):4278. Jiang M, Liu R, Liu L, Kot A, Liu X, Xiao W, Jia J, Li Y, Lam KS, Yao W. PMID: 32855388; PMCID: PMC7453024.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    13. A nephrotoxicity-free, iron-based contrast agent for magnetic resonance imaging of tumors. Biomaterials. 2020 10; 257:120234. Xue X, Bo R, Qu H, Jia B, Xiao W, Yuan Y, Vapniarsky N, Lindstrom A, Wu H, Zhang D, Li L, Ricci M, Ma Z, Zhu Z, Lin TY, Louie AY, Li Y. PMID: 32736259; PMCID: PMC7442595.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    14. Discovery and mechanistic characterization of a structurally-unique membrane active peptide. Biochim Biophys Acta Biomembr. 2020 10 01; 1862(10):183394. Bansal S, Su WC, Budamagunta M, Xiao W, Ajena Y, Liu R, Voss JC, Carney RP, Parikh AN, Lam KS. PMID: 32562695; PMCID: PMC7478859.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    15. Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomater. 2020 05; 108:178-193. Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A. PMID: 32151698; PMCID: PMC8012081.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    16. Sequential Targeting in Crosslinking Nanotheranostics for Tackling the Multibarriers of Brain Tumors. Adv Mater. 2020 Apr; 32(14):e1903759. Wu H, Lu H, Xiao W, Yang J, Du H, Shen Y, Qu H, Jia B, Manna SK, Ramachandran M, Xue X, Ma Z, Xu X, Wang Z, He Y, Lam KS, Zawadzki RJ, Li Y, Lin TY. PMID: 32078198; PMCID: PMC7148201.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    17. Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo. Nat Nanotechnol. 2020 02; 15(2):145-153. Zhang L, Jing D, Jiang N, Rojalin T, Baehr CM, Zhang D, Xiao W, Wu Y, Cong Z, Li JJ, Li Y, Wang L, Lam KS. PMID: 31988501; PMCID: PMC7147967.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    18. Correction to: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 Jul 26; 12(1):83. Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31349855; PMCID: PMC6660960.
      View in: PubMed   Mentions: 1     Fields:    
    19. High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer. J Hematol Oncol. 2019 06 10; 12(1):56. Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T. PMID: 31182116; PMCID: PMC6558829.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    20. Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells. Redox Biol. 2019 06; 24:101189. Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ. PMID: 30986607; PMCID: PMC6463934.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    21. Combinatorial Peptide Microarray Synthesis Based on Microfluidic Impact Printing. ACS Comb Sci. 2019 01 14; 21(1):6-10. Li J, Zhao S, Yang G, Liu R, Xiao W, Disano P, Lam KS, Pan T. PMID: 30521316; PMCID: PMC6335607.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy in vivo. Biomed Opt Express. 2019 Jan 01; 10(1):151-166. Goswami M, Wang X, Zhang P, Xiao W, Karlen SJ, Li Y, Zawadzki RJ, Burns ME, Lam KS, Pugh EN. PMID: 30775090; PMCID: PMC6363190.
      View in: PubMed   Mentions: 4  
    23. A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing. Anal Chem. 2018 12 04; 90(23):13969-13977. Li J, Tan W, Xiao W, Carney RP, Men Y, Li Y, Quon G, Ajena Y, Lam KS, Pan T. PMID: 30358386; PMCID: PMC6467812.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    24. Safety and Efficacy of Osimertinib in the Treatment of a Patient With Metastatic Lung Cancer and Concurrent Somatic EGFR L858R and Germline EGFR T790M Mutations. JCO Precis Oncol. 2018 Nov; 2:1-7. Ma W, Gong J, Shan J, Lewis D, Xiao W, Moore EH, Zhang Y, Hung J, Mans NZ, Wei S, Welborn J, Stollenwerk NS, Lam KS, Li T. PMID: 35135138.
      View in: PubMed   Mentions: 4     Fields:    
    25. Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion. Clin Cancer Res. 2018 09 01; 24(17):4319-4331. Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss S, Wang T, Chen XJ, Carney R, Kung HJ, Duan Y, Ghosh PM, Lam KS. PMID: 29666302; PMCID: PMC6125207.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    26. Corrigendum to 'Tumor-targeting peptides from combinatorial libraries' [Adv Drug Deliv Rev.110-111 (2017) 13-37]. Adv Drug Deliv Rev. 2018 02 01; 125:152. Liu R, Li X, Xiao W, Lam KS. PMID: 29530341.
      View in: PubMed   Mentions:    Fields:    
    27. Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer. J Control Release. 2017 Oct 28; 264:169-179. Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y. PMID: 28847739; PMCID: PMC5632596.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    28. Cholic acid-based novel micellar nanoplatform for delivering FDA-approved taxanes. Nanomedicine (Lond). 2017 May; 12(10):1153-1164. Bharadwaj G, Nhan V, Yang S, Li X, Narayanan A, Macarenco AC, Shi Y, Yang D, Vieira LS, Xiao W, Li Y, Lam KS. PMID: 28447909; PMCID: PMC5480805.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    29. Tumor-targeting peptides from combinatorial libraries. Adv Drug Deliv Rev. 2017 02; 110-111:13-37. Liu R, Li X, Xiao W, Lam KS. PMID: 27210583; PMCID: PMC5856482.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    30. Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors. EJNMMI Res. 2016 Dec; 6(1):18. Xiao W, Li T, Bononi FC, Lac D, Kekessie IA, Liu Y, Sanchez E, Mazloom A, Ma AH, Lin J, Tran J, Yang K, Lam KS, Liu R. PMID: 26922417; PMCID: PMC4769701.
      View in: PubMed   Mentions: 16  
    31. Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin. Mol Cancer Ther. 2016 Feb; 15(2):232-40. Wang Y, Xiao W, Zhang Y, Meza L, Tseng H, Takada Y, Ames JB, Lam KS. PMID: 26719578; PMCID: PMC4747864.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    32. Microfluidic-Enabled Print-to-Screen Platform for High-Throughput Screening of Combinatorial Chemotherapy. Anal Chem. 2015 Oct 20; 87(20):10166-71. Ding Y, Li J, Xiao W, Xiao K, Lee J, Bhardwaj U, Zhu Z, Digiglio P, Yang G, Lam KS, Pan T. PMID: 26334956.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    33. A smart and versatile theranostic nanomedicine platform based on nanoporphyrin. Nat Commun. 2014 Aug 26; 5:4712. Li Y, Lin TY, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, Lam KS. PMID: 25158161; PMCID: PMC4145614.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    34. Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling. Sci Signal. 2014 Mar 18; 7(317):ra27. Jian Z, Han H, Zhang T, Puglisi J, Izu LT, Shaw JA, Onofiok E, Erickson JR, Chen YJ, Horvath B, Shimkunas R, Xiao W, Li Y, Pan T, Chan J, Banyasz T, Tardiff JC, Chiamvimonvat N, Bers DM, Lam KS, Chen-Izu Y. PMID: 24643800; PMCID: PMC4103414.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    35. Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. Nanomedicine (Lond). 2014; 9(12):1807-20. Zhang H, Li Y, Lin TY, Xiao K, Haddad AS, Henderson PT, Jonas BA, Chen M, Xiao W, Liu R, Lam KS, Pan CX. PMID: 24628688; PMCID: PMC4167557.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    36. Immobilized OBOC combinatorial bead array to facilitate multiplicative screening. Comb Chem High Throughput Screen. 2013 Jul; 16(6):441-448. Xiao W, Bononi FC, Townsend J, Li Y, Liu R, Lam KS. PMID: 23488896; PMCID: PMC4560360.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    37. Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins. ACS Nano. 2012 Nov 27; 6(11):9485-95. Li Y, Budamagunta MS, Luo J, Xiao W, Voss JC, Lam KS. PMID: 23106540; PMCID: PMC3922124.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    38. Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer. Int J Nanomedicine. 2012; 7:1587-97. Xiao W, Luo J, Jain T, Riggs JW, Tseng HP, Henderson PT, Cherry SR, Rowland D, Lam KS. PMID: 22605931; PMCID: PMC3352867.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    39. Well-defined, reversible boronate crosslinked nanocarriers for targeted drug delivery in response to acidic pH values and cis-diols. Angew Chem Int Ed Engl. 2012 Mar 19; 51(12):2864-9. Li Y, Xiao W, Xiao K, Berti L, Luo J, Tseng HP, Fung G, Lam KS. PMID: 22253091; PMCID: PMC3545653.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    40. Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery. Biomaterials. 2011 Sep; 32(27):6633-45. Li Y, Xiao K, Luo J, Xiao W, Lee JS, Gonik AM, Kato J, Dong TA, Lam KS. PMID: 21658763; PMCID: PMC3137548.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    41. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials. 2011 May; 32(13):3435-46. Xiao K, Li Y, Luo J, Lee JS, Xiao W, Gonik AM, Agarwal RG, Lam KS. PMID: 21295849; PMCID: PMC3055170.
      View in: PubMed   Mentions: 288     Fields:    Translation:HumansAnimalsCells
    42. The use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handle. Mol Cancer Ther. 2010 Oct; 9(10):2714-23. Xiao W, Wang Y, Lau EY, Luo J, Yao N, Shi C, Meza L, Tseng H, Maeda Y, Kumaresan P, Liu R, Lightstone FC, Takada Y, Lam KS. PMID: 20858725; PMCID: PMC3571112.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    43. Structure-activity relationship studies of targeting ligands against breast cancer cells. J Med Chem. 2009 Nov 12; 52(21):6744-51. Yao N, Xiao W, Meza L, Tseng H, Chuck M, Lam KS. PMID: 19835381.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    44. Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. J Med Chem. 2009 Jan 08; 52(1):126-33. Yao N, Xiao W, Wang X, Marik J, Park SH, Takada Y, Lam KS. PMID: 19055415; PMCID: PMC2836207.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    45. Near-infrared optical imaging in glioblastoma xenograft with ligand-targeting alpha 3 integrin. Eur J Nucl Med Mol Imaging. 2009 Jan; 36(1):94-103. Xiao W, Yao N, Peng L, Liu R, Lam KS. PMID: 18712382; PMCID: PMC2842018.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    46. Rainbow beads: a color coding method to facilitate high-throughput screening and optimization of one-bead one-compound combinatorial libraries. J Comb Chem. 2008 Jul-Aug; 10(4):599-604. Luo J, Zhang H, Xiao W, Kumaresan PR, Shi C, Pan CX, Aina OH, Lam KS. PMID: 18558750.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    47. In vivo optical imaging of human lymphoma xenograft using a library-derived peptidomimetic against alpha4beta1 integrin. Mol Cancer Ther. 2008 Feb; 7(2):432-7. Peng L, Liu R, Andrei M, Xiao W, Lam KS. PMID: 18245670.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    48. Discovery of high-affinity peptide ligands for vancomycin. Biopolymers. 2008; 90(3):421-32. Yao N, Wu CY, Xiao W, Lam KS. PMID: 18260149.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
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