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Anthony Karnezis

Title(s)Associate Professor, Pathology and Laboratory Medicine
SchoolUniversity of California, Davis
Address4400 V Street, Suite 1234
CA 95817
Phone916-734-2651
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium. Br J Cancer. 2020 Jun 18. Martins FC, Couturier DL, Paterson A, Karnezis AN, Chow C, Nazeran TM, Odunsi A, Gentry-Maharaj A, Vrvilo A, Hein A, Talhouk A, Osorio A, Hartkopf AD, Brooks-Wilson A, DeFazio A, Fischer A, Hartmann A, Hernandez BY, McCauley BM, Karpinskyj C, de Sousa CB, Høgdall C, Tiezzi DG, Herpel E, Taran FA, Modugno F, Keeney G, Nelson G, Steed H, Song H, Luk H, Benitez J, Alsop J, Koziak JM, Lester J, Rothstein JH, de Andrade JM, Lundvall L, Paz-Ares L, Robles-Díaz L, Wilkens LR, Garcia MJ, Intermaggio MP, Alcaraz ML, Brett MA, Beckmann MW, Jimenez-Linan M, Anglesio M, Carney ME, Schneider M, Traficante N, Pejovic N, Singh N, Le N, Sinn P, Ghatage P, Erber R, Edwards R, Vierkant R, Ness RB, Leung S, Orsulic S, Brucker SY, Kaufmann SH, Fereday S, Gayther S, Winham SJ, Kommoss S, Pejovic T, Longacre TA, McGuire V, Rhenius V, Sieh W, Shvetsov YB, Whittemore AS, Staebler A, Karlan BY, Rodriguez-Antona C, Bowtell DD, Goode EL, Høgdall E, Candido Dos Reis FJ, Gronwald J, Chang-Claude J, Moysich KB, Kelemen LE, Cook LS, Goodman MT, Fasching PA, Crawford R, Deen S, Menon U, Huntsman DG, Köbel M, Ramus SJ, Pharoah PDP, Brenton JD. PMID: 32555365.
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    2. Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type. Clin Cancer Res. 2020 May 14. Ji JX, Cochrane DR, Tessier-Cloutier B, Chen SY, Ho G, Pathak KV, Alcazar IN, Farnell D, Leung S, Cheng A, Chow C, Colborne S, Negri GL, Kommoss F, Karnezis A, Morin GB, McAlpine JN, Gilks CB, Weissman BE, Trent JM, Hoang L, Pirrotte P, Wang Y, Huntsman DG. PMID: 32409304.
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    3. Proteomic analysis of transitional cell carcinoma-like variant of tubo-ovarian high-grade serous carcinoma. Hum Pathol. 2020 Jul; 101:40-52. Tessier-Cloutier B, Cochrane DR, Karnezis AN, Colborne S, Magrill J, Talhouk A, Zhang J, Leung S, Hughes CS, Piskorz A, Cheng AS, Greening K, du Bois A, Pfisterer J, Soslow RA, Kommoss S, Brenton JD, Morin GB, Gilks CB, Huntsman DG, Kommoss F. PMID: 32360491.
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    4. Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma. Gynecol Oncol. 2020 Jun; 157(3):783-792. Chen H, Gotimer K, De Souza C, Tepper CG, Karnezis AN, Leiserowitz GS, Chien J, Smith LH. PMID: 32253045.
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    5. Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli-Leydig cell tumour, microcystic stromal tumour and their mimics. Histopathology. 2020 Jan; 76(1):11-24. Rabban JT, Karnezis AN, Devine WP. PMID: 31846522.
      View in: PubMed   Mentions: 1     Fields:    
    6. Tubo-Ovarian Transitional Cell Carcinoma and High-grade Serous Carcinoma Show Subtly Different Immunohistochemistry Profiles. Int J Gynecol Pathol. 2019 Nov; 38(6):552-561. Magrill J, Karnezis AN, Tessier-Cloutier B, Talhouk A, Kommoss S, Cochrane D, Chow C, Cheng A, Soslow R, Hauptmann S, du Bois A, Pfisterer J, Gilks CB, Huntsman DG, Kommoss F. PMID: 30059451.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Expression of L1 retrotransposon open reading frame protein 1 in gynecologic cancers. Hum Pathol. 2019 10; 92:39-47. Xia Z, Cochrane DR, Tessier-Cloutier B, Leung S, Karnezis AN, Cheng AS, Farnell DA, Magrill J, Schmidt D, Kommoss S, Kommoss FKF, Kommoss F, McAlpine JN, Gilks CB, Koebel M, Rabban JT, Huntsman DG. PMID: 31220479.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors. Am J Surg Pathol. 2019 05; 43(5):628-638. Karnezis AN, Wang Y, Keul J, Tessier-Cloutier B, Magrill J, Kommoss S, Senz J, Yang W, Proctor L, Schmidt D, Clement PB, Gilks CB, Huntsman DG, Kommoss F. PMID: 30986800.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome. Int J Gynecol Pathol. 2019 Mar; 38(2):189-195. Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB. PMID: 29406447.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type. Mol Cancer Ther. 2018 12; 17(12):2767-2779. Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Santos ND, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, Weissman BE, Huntsman DG. PMID: 30232145.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    11. L1CAM further stratifies endometrial carcinoma patients with no specific molecular risk profile. Br J Cancer. 2018 08; 119(4):480-486. Kommoss FK, Karnezis AN, Kommoss F, Talhouk A, Taran FA, Staebler A, Gilks CB, Huntsman DG, Krämer B, Brucker SY, McAlpine JN, Kommoss S. PMID: 30050154.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. DICER1 hot-spot mutations in ovarian gynandroblastoma. Histopathology. 2018 Aug; 73(2):306-313. Wang Y, Karnezis AN, Magrill J, Tessier-Cloutier B, Lum A, Senz J, Gilks CB, McCluggage WG, Huntsman DG, Kommoss F. PMID: 29660837.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer. Cell. 2018 06 14; 173(7):1755-1769.e22. Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, Smith MA, Ho J, Tse K, Zeng T, Shlafman I, Mayo MR, Moore R, Failmezger H, Heindl A, Wang YK, Bashashati A, Grewal DS, Brown SD, Lai D, Wan ANC, Nielsen CB, Huebner C, Tessier-Cloutier B, Anglesio MS, Bouchard-Côté A, Yuan Y, Wasserman WW, Gilks CB, Karnezis AN, Aparicio S, McAlpine JN, Huntsman DG, Holt RA, Nelson BH, Shah SP. PMID: 29754820.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    14. Final validation of the ProMisE molecular classifier for endometrial carcinoma in a large population-based case series. Ann Oncol. 2018 05 01; 29(5):1180-1188. Kommoss S, McConechy MK, Kommoss F, Leung S, Bunz A, Magrill J, Britton H, Kommoss F, Grevenkamp F, Karnezis A, Yang W, Lum A, Krämer B, Taran F, Staebler A, Lax S, Brucker SY, Huntsman DG, Gilks CB, McAlpine JN, Talhouk A. PMID: 29432521.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. High Frequency of Ovarian Cyst Development in Vhl2B/+;Snf5+/- Mice. Am J Pathol. 2018 07; 188(7):1510-1516. Kuwahara Y, Kennedy LM, Karnezis AN, Mora-Blanco EL, Rogers AB, Fletcher CD, Huntsman DG, Roberts CWM, Rathmell WK, Weissman BE. PMID: 29684361.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    16. Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition. Clin Cancer Res. 2018 04 15; 24(8):1932-1943. Lang JD, Hendricks WPD, Orlando KA, Yin H, Kiefer J, Ramos P, Sharma R, Pirrotte P, Raupach EA, Sereduk C, Tang N, Liang WS, Washington M, Facista SJ, Zismann VL, Cousins EM, Major MB, Wang Y, Karnezis AN, Sekulic A, Hass R, Vanderhyden BC, Nair P, Weissman BE, Huntsman DG, Trent JM. PMID: 29440177.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    17. Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation. Pathology. 2018 Feb; 50(2):238-256. Garg K, Karnezis AN, Rabban JT. PMID: 29373116.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Preclinical Models of Ovarian Cancer: Pathogenesis, Problems, and Implications for Prevention. Clin Obstet Gynecol. 2017 12; 60(4):789-800. Karnezis AN, Cho KR. PMID: 28719396.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    19. Detection and genomic characterization of a mammary-like adenocarcinoma. Cold Spring Harb Mol Case Stud. 2017 Nov; 3(6). Grewal JK, Eirew P, Jones M, Chiu K, Tessier-Cloutier B, Karnezis AN, Karsan A, Mungall A, Zhou C, Yip S, Tinker AV, Laskin J, Marra M, Jones SJM. PMID: 28877932.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Evaluation of endometrial carcinoma prognostic immunohistochemistry markers in the context of molecular classification. J Pathol Clin Res. 2017 Oct; 3(4):279-293. Karnezis AN, Leung S, Magrill J, McConechy MK, Yang W, Chow C, Kobel M, Lee CH, Huntsman DG, Talhouk A, Kommoss F, Gilks CB, McAlpine JN. PMID: 29085668.
      View in: PubMed   Mentions: 2     Fields:    
    21. Clear cell and endometrioid carcinomas: are their differences attributable to distinct cells of origin? J Pathol. 2017 09; 243(1):26-36. Cochrane DR, Tessier-Cloutier B, Lawrence KM, Nazeran T, Karnezis AN, Salamanca C, Cheng AS, McAlpine JN, Hoang LN, Gilks CB, Huntsman DG. PMID: 28678427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type. J Pathol. 2017 07; 242(3):371-383. Wang Y, Chen SY, Karnezis AN, Colborne S, Santos ND, Lang JD, Hendricks WP, Orlando KA, Yap D, Kommoss F, Bally MB, Morin GB, Trent JM, Weissman BE, Huntsman DG. PMID: 28444909.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    23. Human papillomavirus (HPV)-independent vulvar squamous cell carcinoma has a worse prognosis than HPV-associated disease: a retrospective cohort study. Histopathology. 2017 Aug; 71(2):238-246. McAlpine JN, Leung SCY, Cheng A, Miller D, Talhouk A, Gilks CB, Karnezis AN. PMID: 28257152.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes. Nat Genet. 2017 Jun; 49(6):856-865. Wang YK, Bashashati A, Anglesio MS, Cochrane DR, Grewal DS, Ha G, McPherson A, Horlings HM, Senz J, Prentice LM, Karnezis AN, Lai D, Aniba MR, Zhang AW, Shumansky K, Siu C, Wan A, McConechy MK, Li-Chang H, Tone A, Provencher D, de Ladurantaye M, Fleury H, Okamoto A, Yanagida S, Yanaihara N, Saito M, Mungall AJ, Moore R, Marra MA, Gilks CB, Mes-Masson AM, McAlpine JN, Aparicio S, Huntsman DG, Shah SP. PMID: 28436987.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    25. Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet. 2017 May; 49(5):680-691. Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G, Earp MA, Lyra PC, Lee JM, Coetzee S, Beesley J, McGuffog L, Soucy P, Dicks E, Lee A, Barrowdale D, Lecarpentier J, Leslie G, Aalfs CM, Aben KKH, Adams M, Adlard J, Andrulis IL, Anton-Culver H, Antonenkova N, Aravantinos G, Arnold N, Arun BK, Arver B, Azzollini J, Balmaña J, Banerjee SN, Barjhoux L, Barkardottir RB, Bean Y, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bermisheva M, Bernardini MQ, Birrer MJ, Bjorge L, Black A, Blankstein K, Blok MJ, Bodelon C, Bogdanova N, Bojesen A, Bonanni B, Borg Å, Bradbury AR, Brenton JD, Brewer C, Brinton L, Broberg P, Brooks-Wilson A, Bruinsma F, Brunet J, Buecher B, Butzow R, Buys SS, Caldes T, Caligo MA, Campbell I, Cannioto R, Carney ME, Cescon T, Chan SB, Chang-Claude J, Chanock S, Chen XQ, Chiew YE, Chiquette J, Chung WK, Claes KBM, Conner T, Cook LS, Cook J, Cramer DW, Cunningham JM, D'Aloisio AA, Daly MB, Damiola F, Damirovna SD, Dansonka-Mieszkowska A, Dao F, Davidson R, DeFazio A, Delnatte C, Doheny KF, Diez O, Ding YC, Doherty JA, Domchek SM, Dorfling CM, Dörk T, Dossus L, Duran M, Dürst M, Dworniczak B, Eccles D, Edwards T, Eeles R, Eilber U, Ejlertsen B, Ekici AB, Ellis S, Elvira M, Eng KH, Engel C, Evans DG, Fasching PA, Ferguson S, Ferrer SF, Flanagan JM, Fogarty ZC, Fortner RT, Fostira F, Foulkes WD, Fountzilas G, Fridley BL, Friebel TM, Friedman E, Frost D, Ganz PA, Garber J, García MJ, Garcia-Barberan V, Gehrig A, Gentry-Maharaj A, Gerdes AM, Giles GG, Glasspool R, Glendon G, Godwin AK, Goldgar DE, Goranova T, Gore M, Greene MH, Gronwald J, Gruber S, Hahnen E, Haiman CA, Håkansson N, Hamann U, Hansen TVO, Harrington PA, Harris HR, Hauke J, Hein A, Henderson A, Hildebrandt MAT, Hillemanns P, Hodgson S, Høgdall CK, Høgdall E, Hogervorst FBL, Holland H, Hooning MJ, Hosking K, Huang RY, Hulick PJ, Hung J, Hunter DJ, Huntsman DG, Huzarski T, Imyanitov EN, Isaacs C, Iversen ES, Izatt L, Izquierdo A, Jakubowska A, James P, Janavicius R, Jernetz M, Jensen A, Jensen UB, John EM, Johnatty S, Jones ME, Kannisto P, Karlan BY, Karnezis A, Kast K, Kennedy CJ, Khusnutdinova E, Kiemeney LA, Kiiski JI, Kim SW, Kjaer SK, Köbel M, Kopperud RK, Kruse TA, Kupryjanczyk J, Kwong A, Laitman Y, Lambrechts D, Larrañaga N, Larson MC, Lazaro C, Le ND, Le Marchand L, Lee JW, Lele SB, Leminen A, Leroux D, Lester J, Lesueur F, Levine DA, Liang D, Liebrich C, Lilyquist J, Lipworth L, Lissowska J, Lu KH, Lubinnski J, Luccarini C, Lundvall L, Mai PL, Mendoza-Fandiño G, Manoukian S, Massuger LFAG, May T, Mazoyer S, McAlpine JN, McGuire V, McLaughlin JR, McNeish I, Meijers-Heijboer H, Meindl A, Menon U, Mensenkamp AR, Merritt MA, Milne RL, Mitchell G, Modugno F, Moes-Sosnowska J, Moffitt M, Montagna M, Moysich KB, Mulligan AM, Musinsky J, Nathanson KL, Nedergaard L, Ness RB, Neuhausen SL, Nevanlinna H, Niederacher D, Nussbaum RL, Odunsi K, Olah E, Olopade OI, Olsson H, Olswold C, O'Malley DM, Ong KR, Onland-Moret NC, Orr N, Orsulic S, Osorio A, Palli D, Papi L, Park-Simon TW, Paul J, Pearce CL, Pedersen IS, Peeters PHM, Peissel B, Peixoto A, Pejovic T, Pelttari LM, Permuth JB, Peterlongo P, Pezzani L, Pfeiler G, Phillips KA, Piedmonte M, Pike MC, Piskorz AM, Poblete SR, Pocza T, Poole EM, Poppe B, Porteous ME, Prieur F, Prokofyeva D, Pugh E, Pujana MA, Pujol P, Radice P, Rantala J, Rappaport-Fuerhauser C, Rennert G, Rhiem K, Rice P, Richardson A, Robson M, Rodriguez GC, Rodríguez-Antona C, Romm J, Rookus MA, Rossing MA, Rothstein JH, Rudolph A, Runnebaum IB, Salvesen HB, Sandler DP, Schoemaker MJ, Senter L, Setiawan VW, Severi G, Sharma P, Shelford T, Siddiqui N, Side LE, Sieh W, Singer CF, Sobol H, Song H, Southey MC, Spurdle AB, Stadler Z, Steinemann D, Stoppa-Lyonnet D, Sucheston-Campbell LE, Sukiennicki G, Sutphen R, Sutter C, Swerdlow AJ, Szabo CI, Szafron L, Tan YY, Taylor JA, Tea MK, Teixeira MR, Teo SH, Terry KL, Thompson PJ, Thomsen LCV, Thull DL, Tihomirova L, Tinker AV, et al. PMID: 28346442.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    26. Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer. Cancer. 2017 03 01; 123(5):802-813. Talhouk A, McConechy MK, Leung S, Yang W, Lum A, Senz J, Boyd N, Pike J, Anglesio M, Kwon JS, Karnezis AN, Huntsman DG, Gilks CB, McAlpine JN. PMID: 28061006.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    27. The disparate origins of ovarian cancers: pathogenesis and prevention strategies. Nat Rev Cancer. 2017 01; 17(1):65-74. Karnezis AN, Cho KR, Gilks CB, Pearce CL, Huntsman DG. PMID: 27885265.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    28. Of mice and women - Non-ovarian origins of "ovarian" cancer. Gynecol Oncol. 2017 01; 144(1):5-7. Karnezis AN, Cho KR. PMID: 27890279.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    29. Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse. J Pathol. 2016 11; 240(3):341-351. Wu R, Zhai Y, Kuick R, Karnezis AN, Garcia P, Naseem A, Hu TC, Fearon ER, Cho KR. PMID: 27538791.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    30. Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research. Sci Rep. 2016 10 07; 6:34949. Hughes CS, McConechy MK, Cochrane DR, Nazeran T, Karnezis AN, Huntsman DG, Morin GB. PMID: 27713570.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    31. Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas. Mod Pathol. 2016 12; 29(12):1586-1593. Coatham M, Li X, Karnezis AN, Hoang LN, Tessier-Cloutier B, Meng B, Soslow RA, Blake Gilks C, Huntsman DG, Stewart CJ, Postovit LM, Köbel M, Lee CH. PMID: 27562491.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    32. Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics. Histopathology. 2016 Nov; 69(5):727-738. Clarke BA, Witkowski L, Ton Nu TN, Shaw PA, Gilks CB, Huntsman D, Karnezis AN, Sebire N, Lamovec J, Roth LM, Stewart CJ, Hasselblatt M, Foulkes WD, McCluggage WG. PMID: 27100627.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Immunophenotypic features of dedifferentiated endometrial carcinoma - insights from BRG1/INI1-deficient tumours. Histopathology. 2016 Oct; 69(4):560-9. Hoang LN, Lee YS, Karnezis AN, Tessier-Cloutier B, Almandani N, Coatham M, Gilks CB, Soslow RA, Stewart CJ, Köbel M, Lee CH. PMID: 27101785.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. p16 Immunostaining Allows for Accurate Subclassification of Vulvar Squamous Cell Carcinoma Into HPV-Associated and HPV-Independent Cases. Int J Gynecol Pathol. 2016 Jul; 35(4):385-93. Cheng AS, Karnezis AN, Jordan S, Singh N, McAlpine JN, Gilks CB. PMID: 26630231.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    35. Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nat Genet. 2016 07; 48(7):758-67. McPherson A, Roth A, Laks E, Masud T, Bashashati A, Zhang AW, Ha G, Biele J, Yap D, Wan A, Prentice LM, Khattra J, Smith MA, Nielsen CB, Mullaly SC, Kalloger S, Karnezis A, Shumansky K, Siu C, Rosner J, Chan HL, Ho J, Melnyk N, Senz J, Yang W, Moore R, Mungall AJ, Marra MA, Bouchard-Côté A, Gilks CB, Huntsman DG, McAlpine JN, Aparicio S, Shah SP. PMID: 27182968.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    36. The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type. Gynecol Oncol. 2016 06; 141(3):454-460. Witkowski L, Goudie C, Ramos P, Boshari T, Brunet JS, Karnezis AN, Longy M, Knost JA, Saloustros E, McCluggage WG, Stewart CJR, Hendricks WPD, Cunliffe H, Huntsman DG, Pautier P, Levine DA, Trent JM, Berchuck A, Hasselblatt M, Foulkes WD. PMID: 26975901.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality. J Natl Cancer Inst. 2016 Jun; 108(6):djv428. Anglesio MS, Wang YK, Maassen M, Horlings HM, Bashashati A, Senz J, Mackenzie R, Grewal DS, Li-Chang H, Karnezis AN, Sheffield BS, McConechy MK, Kommoss F, Taran FA, Staebler A, Shah SP, Wallwiener D, Brucker S, Gilks CB, Kommoss S, Huntsman DG. PMID: 26832771.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    38. Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas. Mod Pathol. 2016 Mar; 29(3):302-14. Karnezis AN, Hoang LN, Coatham M, Ravn S, Almadani N, Tessier-Cloutier B, Irving J, Meng B, Li X, Chow C, McAlpine J, Kuo KT, Mao TL, Djordjevic B, Soslow RA, Huntsman DG, Blake Gilks C, Köbel M, Lee CH. PMID: 26743474.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    39. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type. J Pathol. 2016 Feb; 238(3):389-400. Karnezis AN, Wang Y, Ramos P, Hendricks WP, Oliva E, D'Angelo E, Prat J, Nucci MR, Nielsen TO, Chow C, Leung S, Kommoss F, Kommoss S, Silva A, Ronnett BM, Rabban JT, Bowtell DD, Weissman BE, Trent JM, Gilks CB, Huntsman DG. PMID: 26356327.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    40. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015 Aug 06; 524(7563):47-53. George J, Lim JS, Jang SJ, Cun Y, Ozretic L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK. PMID: 26168399.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansAnimalsCells
    41. A clinically applicable molecular-based classification for endometrial cancers. Br J Cancer. 2015 Jul 14; 113(2):299-310. Talhouk A, McConechy MK, Leung S, Li-Chang HH, Kwon JS, Melnyk N, Yang W, Senz J, Boyd N, Karnezis AN, Huntsman DG, Gilks CB, McAlpine JN. PMID: 26172027.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    42. Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms. BMC Cancer. 2015 May 19; 15:415. Mackenzie R, Kommoss S, Winterhoff BJ, Kipp BR, Garcia JJ, Voss J, Halling K, Karnezis A, Senz J, Yang W, Prigge ES, Reuschenbach M, Doeberitz MV, Gilks BC, Huntsman DG, Bakkum-Gamez J, McAlpine JN, Anglesio MS. PMID: 25986173.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    43. Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden. J Pathol. 2015 Jun; 236(2):201-9. Anglesio MS, Bashashati A, Wang YK, Senz J, Ha G, Yang W, Aniba MR, Prentice LM, Farahani H, Li Chang H, Karnezis AN, Marra MA, Yong PJ, Hirst M, Gilks B, Shah SP, Huntsman DG. PMID: 25692284.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    44. Loss of the tumor suppressor SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Rare Dis. 2014; 2(1):e967148. Ramos P, Karnezis AN, Hendricks WP, Wang Y, Tembe W, Zismann VL, Legendre C, Liang WS, Russell ML, Craig DW, Farley JH, Monk BJ, Anthony SP, Sekulic A, Cunliffe HE, Huntsman DG, Trent JM. PMID: 26942101.
      View in: PubMed   Mentions:
    45. Corrigendum: Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nature Genetics. 2014 Jul 1; 46(7):759-759. Pilar Ramos, Anthony N Karnezis, David W Craig, Aleksander Sekulic, Megan L Russel, William P D Hendricks, Jason J Corneveaux, Michael T Barrett, Karey Shumansky, Yidong Yang, Sohrab P Shah, Leah M Prentice, Marco A Marra, Jeffrey Kiefer, Victoria L Zismann, Troy A McEachron, Bodour Salhia, Jaime Prat, Emanuela D'Angelo, Blaise A Clarke, Joseph G Pressey, John H Farley, Stephen P Anthony, Richard B S Roden, Heather E Cunliffe, David G Huntsman, Jeffrey M Trent. .
      View in: Publisher Site   Mentions:
    46. Association of tumor morphology with mismatch-repair protein status in older endometrial cancer patients: implications for universal versus selective screening strategies for Lynch syndrome. Am J Surg Pathol. 2014 Jun; 38(6):793-800. Rabban JT, Calkins SM, Karnezis AN, Grenert JP, Blanco A, Crawford B, Chen LM. PMID: 24503759.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    47. Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nat Genet. 2014 May; 46(5):427-9. Ramos P, Karnezis AN, Craig DW, Sekulic A, Russell ML, Hendricks WP, Corneveaux JJ, Barrett MT, Shumansky K, Yang Y, Shah SP, Prentice LM, Marra MA, Kiefer J, Zismann VL, McEachron TA, Salhia B, Prat J, D'Angelo E, Clarke BA, Pressey JG, Farley JH, Anthony SP, Roden RB, Cunliffe HE, Huntsman DG, Trent JM. PMID: 24658001.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    48. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. PLoS Biol. 2014 Mar; 12(3):e1001807. Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, Davoudi S, Hulea L, Yao L, Karnezis AN, Paquet M, Dankort D, Nepveu A. PMID: 24618719.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    49. Pilocytic astrocytomas of the optic nerve and their relation to pilocytic astrocytomas elsewhere in the central nervous system. Mod Pathol. 2013 Oct; 26(10):1279-87. Reis GF, Bloomer MM, Perry A, Phillips JJ, Grenert JP, Karnezis AN, Tihan T. PMID: 23702730.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    50. The diagnostic utility of TP53 and CDKN2A to distinguish ovarian high-grade serous carcinoma from low-grade serous ovarian tumors. Mod Pathol. 2013 Sep; 26(9):1255-63. Altman AD, Nelson GS, Ghatage P, McIntyre JB, Capper D, Chu P, Nation JG, Karnezis AN, Han G, Kalloger SE, Köbel M. PMID: 23558569.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice. Genes Dev. 2013 Mar 01; 27(5):504-13. Soucek L, Whitfield JR, Sodir NM, Massó-Vallés D, Serrano E, Karnezis AN, Swigart LB, Evan GI. PMID: 23475959.
      View in: PubMed   Mentions: 95     Fields:    Translation:Animals
    52. Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia. 2013 Mar; 15(3):249-62. Dumont N, Liu B, Defilippis RA, Chang H, Rabban JT, Karnezis AN, Tjoe JA, Marx J, Parvin B, Tlsty TD. PMID: 23479504.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    53. Transitional cell-like morphology in ovarian endometrioid carcinoma: morphologic, immunohistochemical, and behavioral features distinguishing it from high-grade serous carcinoma. Am J Surg Pathol. 2013 Jan; 37(1):24-37. Karnezis AN, Aysal A, Zaloudek CJ, Rabban JT. PMID: 23108017.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability. Am J Surg Pathol. 2012 Feb; 36(2):163-72. Aysal A, Karnezis A, Medhi I, Grenert JP, Zaloudek CJ, Rabban JT. PMID: 22189970.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    55. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat Med. 2011 Oct 09; 17(11):1504-8. Park KS, Martelotto LG, Peifer M, Sos ML, Karnezis AN, Mahjoub MR, Bernard K, Conklin JF, Szczepny A, Yuan J, Guo R, Ospina B, Falzon J, Bennett S, Brown TJ, Markovic A, Devereux WL, Ocasio CA, Chen JK, Stearns T, Thomas RK, Dorsch M, Buonamici S, Watkins DN, Peacock CD, Sage J. PMID: 21983857.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    56. Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell. 2011 May 13; 145(4):571-83. Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD. PMID: 21565614.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansAnimalsCells
    57. Endogenous Myc maintains the tumor microenvironment. Genes Dev. 2011 May 01; 25(9):907-16. Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L. PMID: 21478273.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    58. Non-epithelial ovarian tumours: a review of selected patterns that mimic epithelial tumours and other high-grade malignancies. Diagnostic Histopathology. 2011 Apr 1; 17(4):153-164. Joseph T. Rabban, Anthony N. Karnezis, Charles J. Zaloudek. .
      View in: Publisher Site   Mentions:
    59. Junctional epithelial zones of the fallopian tube: cancer hotspots? Int J Gynecol Pathol. 2011 Jan; 30(1):1-3. Rabban JT, Karnezis AN, Zaloudek CJ. PMID: 21131841.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    60. Neural stem cells and their role in the pathology and classification of central nervous system tumors. Turk Patoloji Derg. 2011 Jan; 27(1):1-11. Tihan T, Pekmezci M, Karnezis A. PMID: 21469420.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    61. Selective activation of p53-mediated tumour suppression in high-grade tumours. Nature. 2010 Nov 25; 468(7323):567-71. Junttila MR, Karnezis AN, Garcia D, Madriles F, Kortlever RM, Rostker F, Brown Swigart L, Pham DM, Seo Y, Evan GI, Martins CP. PMID: 21107427.
      View in: PubMed   Mentions: 106     Fields:    Translation:Animals
    62. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Res. 2010 May 15; 70(10):3877-83. Schaffer BE, Park KS, Yiu G, Conklin JF, Lin C, Burkhart DL, Karnezis AN, Sweet-Cordero EA, Sage J. PMID: 20406986.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    63. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet. 2009 May; 41(5):544-52. Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky WE, You MJ, DePinho RA, McMahon M, Bosenberg M. PMID: 19282848.
      View in: PubMed   Mentions: 394     Fields:    Translation:AnimalsCells
    64. The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. Oncogene. 2009 Mar 12; 28(10):1393-9. Ho VM, Schaffer BE, Karnezis AN, Park KS, Sage J. PMID: 19151761.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    65. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell. 2008 Dec 09; 14(6):447-57. Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K, Bui DA, Brown-Swigart L, Johnson L, Evan GI. PMID: 19061836.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    66. Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. Nat Genet. 2008 Oct; 40(10):1240-4. To MD, Wong CE, Karnezis AN, Del Rosario R, Di Lauro R, Balmain A. PMID: 18758463.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    67. Modelling Myc inhibition as a cancer therapy. Nature. 2008 Oct 02; 455(7213):679-83. Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB, Nasi S, Evan GI. PMID: 18716624.
      View in: PubMed   Mentions: 285     Fields:    Translation:Animals
    68. Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancer. J Thorac Oncol. 2006 Nov; 1(9):943-8. Raz DJ, Zell JA, Karnezis AN, Odisho A, Ignatius Ou SH, Anton-Culver H, Jablons DM. PMID: 17409976.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers. J Clin Invest. 2001 Aug; 108(3):383-90. Karnezis AN, Dorokhov M, Grompe M, Zhu L. PMID: 11489931.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    70. pRB and p107 have distinct effects when expressed in pRB-deficient tumor cells at physiologically relevant levels. Oncogene. 2000 Aug 10; 19(34):3878-87. Jiang H, Karnezis AN, Tao M, Guida PM, Zhu L. PMID: 10951581.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    71. Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes. Hepatology. 1999 Oct; 30(4):903-13. Oren R, Dabeva MD, Karnezis AN, Petkov PM, Rosencrantz R, Sandhu JP, Moss SF, Wang S, Hurston E, Laconi E, Holt PR, Thung SN, Zhu L, Shafritz DA. PMID: 10498641.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    72. Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. J Biol Chem. 1998 Aug 07; 273(32):20448-55. Engelman JA, Lee RJ, Karnezis A, Bearss DJ, Webster M, Siegel P, Muller WJ, Windle JJ, Pestell RG, Lisanti MP. PMID: 9685399.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    73. Induction of cyclin D1 by simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):12861-6. Watanabe G, Howe A, Lee RJ, Albanese C, Shu IW, Karnezis AN, Zon L, Kyriakis J, Rundell K, Pestell RG. PMID: 8917510.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    74. Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis. J Neuropathol Exp Neurol. 1996 Sep; 55(9):1009-20. Shambaugh GE, Lee RJ, Watanabe G, Erfurth F, Karnezis AN, Koch AE, Haines GK, Halloran M, Brody BA, Pestell RG. PMID: 8800097.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    75. Cloning and subcellular localization of human mitochondrial hsp70. J Biol Chem. 1995 Jan 27; 270(4):1705-10. Bhattacharyya T, Karnezis AN, Murphy SP, Hoang T, Freeman BC, Phillips B, Morimoto RI. PMID: 7829505.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
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