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Toward telomere-to-telomere cat genomes for precision medicine and conservation biology. Genome Res. 2024 06 25; 34(5):655-664.
Murphy WJ, Harris AJ. PMID: 38849156; PMCID: PMC11216403.
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PubMed Mentions:
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Potential roles of sex-linked differences in obesity and cancer immunotherapy: revisiting the obesity paradox. NPJ Metab Health Dis. 2024; 2(1):5.
Vick LV, Rosario S, Riess JW, Canter RJ, Mukherjee S, Monjazeb AM, Murphy WJ. PMID: 38800540; PMCID: PMC11116109.
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PubMed Mentions:
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Preclinical evaluation and first-in-dog clinical trials of PBMC-expanded natural killer cells for adoptive immunotherapy in dogs with cancer. J Immunother Cancer. 2024 Apr 16; 12(4).
Razmara AM, Farley LE, Harris RM, Judge SJ, Lammers M, Iranpur KR, Johnson EG, Dunai C, Murphy WJ, Brown CT, Rebhun RB, Kent MS, Canter RJ. PMID: 38631708; PMCID: PMC11029326.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science. 2024 Mar 29; 383(6690):eabn3263.
Wirthlin ME, Schmid TA, Elie JE, Zhang X, Kowalczyk A, Redlich R, Shvareva VA, Rakuljic A, Ji MB, Bhat NS, Kaplow IM, Schäffer DE, Lawler AJ, Wang AZ, Phan BN, Annaldasula S, Brown AR, Lu T, Lim BK, Azim E, Zoonomia Consortium, Clark NL, Meyer WK, Pond SLK, Chikina M, Yartsev MM, Pfenning AR, Andrews G, Armstrong JC, Bianchi M, Birren BW, Bredemeyer KR, Breit AM, Christmas MJ, Clawson H, Damas J, Di Palma F, Diekhans M, Dong MX, Eizirik E, Fan K, Fanter C, Foley NM, Forsberg-Nilsson K, Garcia CJ, Gatesy J, Gazal S, Genereux DP, Goodman L, Grimshaw J, Halsey MK, Harris AJ, Hickey G, Hiller M, Hindle AG, Hubley RM, Hughes GM, Johnson J, Juan D, Kaplow IM, Karlsson EK, Keough KC, Kirilenko B, Koepfli KP, Korstian JM, Kowalczyk A, Kozyrev SV, Lawler AJ, Lawless C, Lehmann T, Levesque DL, Lewin HA, Li X, Lind A, Lindblad-Toh K, Mackay-Smith A, Marinescu VD, Marques-Bonet T, Mason VC, Meadows JRS, Meyer WK, Moore JE, Moreira LR, Moreno-Santillan DD, Morrill KM, Muntané G, Murphy WJ, Navarro A, Nweeia M, Ortmann S, Osmanski A, Paten B, Paulat NS, Pfenning AR, Phan BN, Pollard KS, Pratt HE, Ray DA, Reilly SK, Rosen JR, Ruf I, Ryan L, Ryder OA, Sabeti PC, Schäffer DE, Serres A, Shapiro B, Smit AFA, Springer M, Srinivasan C, Steiner C, Storer JM, Sullivan KAM, Sullivan PF, Sundström E, Supple MA, Swofford R, Talbot JE, Teeling E, Turner-Maier J, Valenzuela A, Wagner F, Wallerman O, Wang C, Wang J, Weng Z, Wilder AP, Wirthlin ME, Xue JR, Zhang X. PMID: 38422184; PMCID: PMC11313673.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Low-Dose Sorafenib Promotes Cancer Stem Cell Expansion and Accelerated Tumor Progression in Soft Tissue Sarcomas. Int J Mol Sci. 2024 Mar 15; 25(6).
Cruz SM, Iranpur KR, Judge SJ, Ames E, Sturgill IR, Farley LE, Darrow MA, Crowley JS, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 38542325; PMCID: PMC10969893.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Suppressive effects of obesity on NK cells: is it time to incorporate obesity as a clinical variable for NK cell-based cancer immunotherapy regimens? J Immunother Cancer. 2024 Mar 13; 12(3).
Canter RJ, Judge SJ, Collins CP, Yoon DJ, Murphy WJ. PMID: 38485185; PMCID: PMC10941146.
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PubMed Mentions: Fields:
Translation:
HumansCells
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The immunobiology of SARS-CoV-2 infection and vaccine responses: potential influences of cross-reactive memory responses and aging on efficacy and off-target effects. Front Immunol. 2024; 15:1345499.
Collins CP, Longo DL, Murphy WJ. PMID: 38469293; PMCID: PMC10925677.
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PubMed Mentions: Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
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MSCs mediate long-term efficacy in a Crohn's disease model by sustained anti-inflammatory macrophage programming via efferocytosis. NPJ Regen Med. 2024 Jan 20; 9(1):6.
Dave M, Dev A, Somoza RA, Zhao N, Viswanath S, Mina PR, Chirra P, Obmann VC, Mahabeleshwar GH, Menghini P, Durbin-Johnson B, Nolta J, Soto C, Osme A, Khuat LT, Murphy WJ, Caplan AI, Cominelli F. PMID: 38245543; PMCID: PMC10799947.
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PubMed Mentions:
1
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Karyotypic stasis and swarming influenced the evolution of viral tolerance in a species-rich bat radiation. Cell Genom. 2024 Feb 14; 4(2):100482.
Foley NM, Harris AJ, Bredemeyer KR, Ruedi M, Puechmaille SJ, Teeling EC, Criscitiello MF, Murphy WJ. PMID: 38237599; PMCID: PMC10879000.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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The genome of the black-footed cat: Revealing a rich natural history and urgent conservation priorities for small felids. Proc Natl Acad Sci U S A. 2024 Jan 09; 121(2):e2310763120.
Yuan J, Kitchener AC, Lackey LB, Sun T, Jiangzuo Q, Tuohetahong Y, Zhao L, Yang P, Wang G, Huang C, Wang J, Hou W, Liu Y, Chen W, Mi D, Murphy WJ, Li G. PMID: 38165928; PMCID: PMC10786289.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Potential role of anti-Idiotype responses on the neurological effects of post-acute sequelae of COVID-19 (PASC). Brain Behav Immun. 2024 02; 116:317-320.
Murphy WJ, Collins CP, Ashwood P. PMID: 38123027.
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PubMed Mentions: Fields:
Translation:
Humans
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Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution. Nat Genet. 2023 Nov; 55(11):1953-1963.
Bredemeyer KR, Hillier L, Harris AJ, Hughes GM, Foley NM, Lawless C, Carroll RA, Storer JM, Batzer MA, Rice ES, Davis BW, Raudsepp T, O'Brien SJ, Lyons LA, Warren WC, Murphy WJ. PMID: 37919451; PMCID: PMC10845050.
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PubMed Mentions:
4 Fields:
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Missing a "Missing Self" Mechanism: Modeling and Detection of Ly49 Expression in Canine NK Cells. Immunohorizons. 2023 Nov 01; 7(11):760-770.
Gingrich AA, Razmara AM, Gingrich PW, Rebhun RB, Murphy WJ, Kent MS, Brown CT, Siegel JB, Canter RJ. PMID: 37971282; PMCID: PMC10696421.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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How genomic insights into the evolutionary history of clouded leopards inform their conservation. Sci Adv. 2023 10 06; 9(40):eadh9143.
Yuan J, Wang G, Zhao L, Kitchener AC, Sun T, Chen W, Huang C, Wang C, Xu X, Wang J, Lu H, Xu L, Jiangzuo Q, Murphy WJ, Wu D, Li G. PMID: 37801506; PMCID: PMC10558132.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Regulation of human and mouse bystander T cell activation responses by PD-1. JCI Insight. 2023 09 22; 8(18).
Le CT, Vick LV, Collins C, Dunai C, Sheng MK, Khuat LT, Barao I, Judge SJ, Aguilar EG, Curti B, Dave M, Longo DL, Blazar BR, Canter RJ, Monjazeb AM, Murphy WJ. PMID: 37737264; PMCID: PMC10561715.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Atezolizumab plus stereotactic ablative radiotherapy for medically inoperable patients with early-stage non-small cell lung cancer: a multi-institutional phase I trial. Nat Commun. 2023 09 02; 14(1):5332.
Monjazeb AM, Daly ME, Luxardi G, Maverakis E, Merleev AA, Marusina AI, Borowsky A, Mirhadi A, Shiao SL, Beckett L, Chen S, Eastham D, Li T, Vick LV, McGee HM, Lara F, Garcia L, Morris LA, Canter RJ, Riess JW, Schalper KA, Murphy WJ, Kelly K. PMID: 37658083; PMCID: PMC10474145.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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DNA methylation networks underlying mammalian traits. Science. 2023 08 11; 381(6658):eabq5693.
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter G, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chavez AS, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke S, Cook JA, Cooper LN, Cossette ML, Day J, DeYoung J, Dirocco S, Dold C, Dunnum JL, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Fei Z, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Goya RG, Grant MJ, Green CB, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaître JF, Levine AJ, Li X, Li C, Lim AR, Lin DTS, Lindemann DM, Liphardt SW, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Murphy WJ, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, Nyamsuren B, O'Brien JK, Ginn PO, Odom DT, Ophir AG, Osborn S, Ostrander EA, Parsons KM, Paul KC, Pedersen AB, Pellegrini M, Peters KJ, Petersen JL, Pietersen DW, Pinho GM, Plassais J, Poganik JR, Prado NA, Reddy P, Rey B, Ritz BR, Robbins J, Rodriguez M, Russell J, Rydkina E, Sailer LL, Salmon AB, Sanghavi A, Schachtschneider KM, Schmitt D, Schmitt T, Schomacher L, Schook LB, Sears KE, Seifert AW, Shafer ABA, Shindyapina AV, Simmons M, Singh K, Sinha I, Slone J, Snell RG, Soltanmohammadi E, Spangler ML, Spriggs M, Staggs L, Stedman N, Steinman KJ, Stewart DT, Sugrue VJ, Szladovits B, Takahashi JS, Takasugi M, Teeling EC, Thompson MJ, Van Bonn B, Vernes SC, Villar D, Vinters HV, Vu H, Wallingford MC, Wang N, Wilkinson GS, Williams RW, Yan Q, Yao M, Young BG, Zhang B, Zhang Z, Zhao Y, Zhao P, Zhou W, Zoller JA, Ernst J, Seluanov A, Gorbunova V, Yang XW, Raj K, Horvath S. PMID: 37561875; PMCID: PMC11180965.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Multifaceted effects of obesity on cancer immunotherapies: Bridging preclinical models and clinical data. Semin Cancer Biol. 2023 10; 95:88-102.
Vick LV, Canter RJ, Monjazeb AM, Murphy WJ. PMID: 37499846; PMCID: PMC10836337.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma. Front Immunol. 2023; 14:1230534.
Cruz SM, Sholevar CJ, Judge SJ, Darrow MA, Iranpur KR, Farley LE, Lammers M, Razmara AM, Dunai C, Gingrich AA, Persky J, Mori H, Thorpe SW, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 37545516; PMCID: PMC10401426.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers. Int J Mol Sci. 2023 Jun 29; 24(13).
Rosario SR, Dong B, Zhang Y, Hsiao HH, Isenhart E, Wang J, Siegel EM, Monjazeb AM, Owen DH, Dey P, Tabung FK, Spakowicz DJ, Murphy WJ, Edge S, Yendamuri S, Ibrahimi S, Kolesar JM, McDonald PH, Vadehra D, Churchman M, Liu S, Kalinski P, Mukherjee S. PMID: 37446025; PMCID: PMC10342094.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis. J Allergy Clin Immunol. 2023 09; 152(3):656-666.
Kim J, Lee J, Li X, Lee HS, Kim K, Chaparala V, Murphy W, Zhou W, Cao J, Lowes MA, Krueger JG. PMID: 37271319; PMCID: PMC11057969.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Androgen receptor blockade resistance with enzalutamide in prostate cancer results in immunosuppressive alterations in the tumor immune microenvironment. J Immunother Cancer. 2023 05; 11(5).
Xu P, Yang JC, Chen B, Nip C, Van Dyke JE, Zhang X, Chen HW, Evans CP, Murphy WJ, Liu C. PMID: 37147019; PMCID: PMC10163595.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Evolutionary constraint and innovation across hundreds of placental mammals. Science. 2023 04 28; 380(6643):eabn3943.
Christmas MJ, Kaplow IM, Genereux DP, Dong MX, Hughes GM, Li X, Sullivan PF, Hindle AG, Andrews G, Armstrong JC, Bianchi M, Breit AM, Diekhans M, Fanter C, Foley NM, Goodman DB, Goodman L, Keough KC, Kirilenko B, Kowalczyk A, Lawless C, Lind AL, Meadows JRS, Moreira LR, Redlich RW, Ryan L, Swofford R, Valenzuela A, Wagner F, Wallerman O, Brown AR, Damas J, Fan K, Gatesy J, Grimshaw J, Johnson J, Kozyrev SV, Lawler AJ, Marinescu VD, Morrill KM, Osmanski A, Paulat NS, Phan BN, Reilly SK, Schäffer DE, Steiner C, Supple MA, Wilder AP, Wirthlin ME, Xue JR, Zoonomia Consortium§, Birren BW, Gazal S, Hubley RM, Koepfli KP, Marques-Bonet T, Meyer WK, Nweeia M, Sabeti PC, Shapiro B, Smit AFA, Springer MS, Teeling EC, Weng Z, Hiller M, Levesque DL, Lewin HA, Murphy WJ, Navarro A, Paten B, Pollard KS, Ray DA, Ruf I, Ryder OA, Pfenning AR, Lindblad-Toh K, Karlsson EK. PMID: 37104599; PMCID: PMC10250106.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Relating enhancer genetic variation across mammals to complex phenotypes using machine learning. Science. 2023 04 28; 380(6643):eabm7993.
Kaplow IM, Lawler AJ, Schäffer DE, Srinivasan C, Sestili HH, Wirthlin ME, Phan BN, Prasad K, Brown AR, Zhang X, Foley K, Genereux DP, Zoonomia Consortium**, Karlsson EK, Lindblad-Toh K, Meyer WK, Pfenning AR. PMID: 37104615; PMCID: PMC10322212.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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A genomic timescale for placental mammal evolution. Science. 2023 04 28; 380(6643):eabl8189.
Foley NM, Mason VC, Harris AJ, Bredemeyer KR, Damas J, Lewin HA, Eizirik E, Gatesy J, Karlsson EK, Lindblad-Toh K, Zoonomia Consortium‡, Springer MS, Murphy WJ. PMID: 37104581; PMCID: PMC10233747.
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PubMed Mentions:
23 Fields:
Translation:
Animals
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The contribution of historical processes to contemporary extinction risk in placental mammals. Science. 2023 04 28; 380(6643):eabn5856.
Wilder AP, Supple MA, Subramanian A, Mudide A, Swofford R, Serres-Armero A, Steiner C, Koepfli KP, Genereux DP, Karlsson EK, Lindblad-Toh K, Marques-Bonet T, Munoz Fuentes V, Foley K, Meyer WK, Zoonomia Consortium‡, Ryder OA, Shapiro B. PMID: 37104572; PMCID: PMC10184782.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Leveraging base-pair mammalian constraint to understand genetic variation and human disease. Science. 2023 04 28; 380(6643):eabn2937.
Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wang C, Wallerman O, Xue J, Yao S, Sun Q, Szatkiewicz J, Wen J, Huckins LM, Lawler A, Keough KC, Zheng Z, Zeng J, Wray NR, Li Y, Johnson J, Chen J, Zoonomia Consortium§, Paten B, Reilly SK, Hughes GM, Weng Z, Pollard KS, Pfenning AR, Forsberg-Nilsson K, Karlsson EK, Lindblad-Toh K. PMID: 37104612; PMCID: PMC10259825.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
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Three-dimensional genome rewiring in loci with human accelerated regions. Science. 2023 04 28; 380(6643):eabm1696.
Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Zoonomia Consortium§, Nowakowski T, Ahituv N, Pollen A, Pollard KS. PMID: 37104607; PMCID: PMC10999243.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Insights into mammalian TE diversity through the curation of 248 genome assemblies. Science. 2023 04 28; 380(6643):eabn1430.
Osmanski AB, Paulat NS, Korstian J, Grimshaw JR, Halsey M, Sullivan KAM, Moreno-Santillán DD, Crookshanks C, Roberts J, Garcia C, Johnson MG, Densmore LD, Stevens RD, Zoonomia Consortium†, Rosen J, Storer JM, Hubley R, Smit AFA, Dávalos LM, Karlsson EK, Lindblad-Toh K, Ray DA. PMID: 37104570; PMCID: PMC11103246.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs. Science. 2023 04 28; 380(6643):eabn5887.
Moon KL, Huson HJ, Morrill K, Wang MS, Li X, Srikanth K, Zoonomia Consortium, Lindblad-Toh K, Svenson GJ, Karlsson EK, Shapiro B. PMID: 37104591; PMCID: PMC10184777.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Mammalian evolution of human cis-regulatory elements and transcription factor binding sites. Science. 2023 04 28; 380(6643):eabn7930.
Andrews G, Fan K, Pratt HE, Phalke N, Zoonomia Consortium§, Karlsson EK, Lindblad-Toh K, Gazal S, Moore JE, Weng Z. PMID: 37104580.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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The functional and evolutionary impacts of human-specific deletions in conserved elements. Science. 2023 04 28; 380(6643):eabn2253.
Xue JR, Mackay-Smith A, Mouri K, Garcia MF, Dong MX, Akers JF, Noble M, Li X, Zoonomia Consortium†, Lindblad-Toh K, Karlsson EK, Noonan JP, Capellini TD, Brennand KJ, Tewhey R, Sabeti PC, Reilly SK. PMID: 37104592; PMCID: PMC10202372.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Integrating gene annotation with orthology inference at scale. Science. 2023 04 28; 380(6643):eabn3107.
Kirilenko BM, Munegowda C, Osipova E, Jebb D, Sharma V, Blumer M, Morales AE, Ahmed AW, Kontopoulos DG, Hilgers L, Lindblad-Toh K, Karlsson EK, Zoonomia Consortium‡, Hiller M. PMID: 37104600; PMCID: PMC10193443.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript. Sci Transl Med. 2023 03 22; 15(688):eabf4077.
Dindot SV, Christian S, Murphy WJ, Berent A, Panagoulias J, Schlafer A, Ballard J, Radeva K, Robinson R, Myers L, Jepp T, Shaheen H, Hillman P, Konganti K, Hillhouse A, Bredemeyer KR, Black L, Douville J, FIRE consortium, FIRE Consortium. PMID: 36947593.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. Am J Transplant. 2023 08; 23(8):1102-1115.
Larson JH, Jin S, Loschi M, Bolivar Wagers S, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, Serody JS, Maillard I, Kean LS, Kim SV, Littman DR, Blazar BR. PMID: 36878433; PMCID: PMC10475494.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Drilling down interferon in GVHD/GVL. Blood. 2023 02 23; 141(8):821-823.
Murphy WJ. PMID: 36821188.
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PubMed Mentions: Fields:
Translation:
Animals
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Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the "obesity paradox". Front Immunol. 2022; 13:1012016.
Vick LV, Collins CP, Khuat LT, Wang Z, Dunai C, Aguilar EG, Stoffel K, Yendamuri S, Smith R, Mukherjee S, Barbi J, Canter RJ, Monjazeb AM, Murphy WJ. PMID: 36776393; PMCID: PMC9910174.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis. J Immunother Cancer. 2023 01; 11(1).
Perry LM, Cruz SM, Kleber KT, Judge SJ, Darrow MA, Jones LB, Basmaci UN, Joshi N, Settles ML, Durbin-Johnson BP, Gingrich AA, Monjazeb AM, Carr-Ascher J, Thorpe SW, Murphy WJ, Eisen JA, Canter RJ. PMID: 36599469; PMCID: PMC9815021.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Giving alloHSCT a needed LIF(t). Blood. 2022 11 10; 140(19):2008-2009.
Murphy WJ. PMID: 36355467.
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PubMed Mentions: Fields:
Translation:
Humans
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The Immunotherapy and Immunosuppressive Signaling in Therapy-Resistant Prostate Cancer. Biomedicines. 2022 Jul 22; 10(8).
Xu P, Wasielewski LJ, Yang JC, Cai D, Evans CP, Murphy WJ, Liu C. PMID: 35892678; PMCID: PMC9394279.
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PubMed Mentions:
11
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Transcriptome Analysis of Tumor-Infiltrating Lymphocytes Identifies NK Cell Gene Signatures Associated With Lymphocyte Infiltration and Survival in Soft Tissue Sarcomas. Front Immunol. 2022; 13:893177.
Judge SJ, Bloomstein JD, Sholevar CJ, Darrow MA, Stoffel KM, Vick LV, Dunai C, Cruz SM, Razmara AM, Monjazeb AM, Rebhun RB, Murphy WJ, Canter RJ. PMID: 35874727; PMCID: PMC9300876.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response. J Immunother Cancer. 2022 06; 10(6).
Rebhun RB, York D, Cruz SM, Judge SJ, Razmara AM, Farley LE, Brady RV, Johnson EG, Burton JH, Willcox J, Wittenburg LA, Woolard K, Dunai C, Stewart SL, Sparger EE, Withers SS, Gingrich AA, Skorupski KA, Al-Nadaf S, LeJeune AT, Culp WT, Murphy WJ, Kent MS, Canter RJ. PMID: 35680383; PMCID: PMC9174838.
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Retinoic acid signaling acts as a rheostat to balance Treg function. Cell Mol Immunol. 2022 07; 19(7):820-833.
Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, Murphy WJ, Maillard I, Hill GR, Munn DH, Zeiser R, Kean LS, Rathmell JC, Chi H, Noelle RJ, Blazar BR. PMID: 35581350; PMCID: PMC9243059.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes. Blood. 2022 05 12; 139(19):2983-2997.
Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Luznik L, Maillard I, Hill GR, MacDonald KPA, Munn DH, Serody JS, Murphy WJ, Kean LS, Zhang Y, Bradner JE, Qi J, Blazar BR. PMID: 35226736; PMCID: PMC9101246.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion. Nat Commun. 2022 03 21; 13(1):1511.
Jiang N, Xie B, Xiao W, Fan M, Xu S, Duan Y, Hamsafar Y, Evans AC, Huang J, Zhou W, Lin X, Ye N, Wanggou S, Chen W, Jing D, Fragoso RC, Dugger BN, Wilson PF, Coleman MA, Xia S, Li X, Sun LQ, Monjazeb AM, Wang A, Murphy WJ, Kung HJ, Lam KS, Chen HW, Li JJ. PMID: 35314680; PMCID: PMC8938495.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
-
Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination. Reply. N Engl J Med. 2022 03 03; 386(9):898-899.
Murphy WJ, Longo DL. PMID: 35108468.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
-
Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects. Blood. 2021 12 16; 138(24):2583-2588.
Khuat LT, Vick LV, Dunai C, Collins CP, More SK, Le CT, Pai CS, Stoffel KM, Maverakis E, Canter RJ, Monjazeb AM, Longo DL, Abedi M, Choi E, Blazar BR, Dave M, Murphy WJ. PMID: 34424962; PMCID: PMC8678998.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination. N Engl J Med. 2022 Jan 27; 386(4):394-396.
Murphy WJ, Longo DL. PMID: 34818473.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Activation status dictates the function of unlicensed natural killer cells in mice and humans. Blood Adv. 2021 10 26; 5(20):4219-4232.
Aguilar EG, Dunai C, Judge SJ, Zamora AE, Khuat LT, Vick LV, Collins CP, Stoffel KM, Alvarez M, Barao I, Miller JS, Blazar BR, Chevallier P, Retiere C, Canter RJ, Murphy WJ. PMID: 34496010; PMCID: PMC8945636.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice. Front Immunol. 2021; 12:752484.
Khuat LT, Vick LV, Choi E, Dunai C, Merleev AA, Maverakis E, Blazar BR, Monjazeb AM, Murphy WJ. PMID: 34707616; PMCID: PMC8542879.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target. Front Immunol. 2021; 12:670309.
Gingrich AA, Reiter TE, Judge SJ, York D, Yanagisawa M, Razmara A, Sturgill I, Basmaci UN, Brady RV, Stoffel K, Murphy WJ, Rebhun RB, Brown CT, Canter RJ. PMID: 34594320; PMCID: PMC8476892.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR. J Immunother Cancer. 2021 09; 9(9).
Bayless NL, Bluestone JA, Bucktrout S, Butterfield LH, Jaffee EM, Koch CA, Roep BO, Sharpe AH, Murphy WJ, Villani AC, Walunas TL. PMID: 34479924; PMCID: PMC8420733.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Genomic architecture constrained placental mammal X Chromosome evolution. Genome Res. 2021 08; 31(8):1353-1365.
Brashear WA, Bredemeyer KR, Murphy WJ. PMID: 34301625; PMCID: PMC8327908.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
The urgent need for more basic research on SARS-Cov2 infection and vaccines in assessing potential psychoneurological effects using maternal immune activation (MIA) and other preclinical modeling. Brain Behav Immun. 2021 10; 97:1-3.
Murphy WJ. PMID: 34217811; PMCID: PMC8247198.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Ultracontinuous Single Haplotype Genome Assemblies for the Domestic Cat (Felis catus) and Asian Leopard Cat (Prionailurus bengalensis). J Hered. 2021 03 29; 112(2):165-173.
Bredemeyer KR, Harris AJ, Li G, Zhao L, Foley NM, Roelke-Parker M, O'Brien SJ, Lyons LA, Warren WC, Murphy WJ. PMID: 33305796; PMCID: PMC8006817.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
-
Skin-Resident β2AR Signaling Delays Burn Wound Healing. J Invest Dermatol. 2021 08; 141(8):2098-2101.e4.
Nguyen AV, Caryotakis SE, Wang M, Gallegos A, Bagood MD, Dunai C, Bindra G, Murphy WJ, Isseroff RR, Soulika AM. PMID: 33667431.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses. Blood. 2021 02 25; 137(8):1090-1103.
Thangavelu G, Wang C, Loschi M, Saha A, Osborn MJ, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, Zeiser R, Maillard I, Serody JS, Murphy WJ, Munn DH, Blumberg B, Brown C, Kuchroo V, Kean LS, Hippen KL, Noelle RJ, Blazar BR. PMID: 32976550; PMCID: PMC7907720.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms. Cancers (Basel). 2021 Feb 10; 13(4).
Monjazeb AM, Wang Z, Vick LV, Dunai C, Minnar C, Khuat LT, Murphy WJ. PMID: 33578798; PMCID: PMC7916633.
View in:
PubMed Mentions:
2
-
The emerging roles of the gut microbiome in allogeneic hematopoietic stem cell transplantation. Gut Microbes. 2021 Jan-Dec; 13(1):1966262.
Khuat LT, Dave M, Murphy WJ. PMID: 34455917; PMCID: PMC8436969.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Re-Examining the Paradigm of Impaired Healing in the Aged Murine Excision Wound Model. J Invest Dermatol. 2021 04; 141(4S):1071-1075.e4.
Bagood MD, Gallegos AC, Medina Lopez AI, Pham VX, Yoon DJ, Fregoso DR, Yang HY, Murphy WJ, Isseroff RR. PMID: 33259830.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation. Sci Transl Med. 2020 11 25; 12(571).
Khuat LT, Le CT, Pai CS, Shields-Cutler RR, Holtan SG, Rashidi A, Parker SL, Knights D, Luna JI, Dunai C, Wang Z, Sturgill IR, Stoffel KM, Merleev AA, More SK, Maverakis E, Raybould HE, Chen M, Canter RJ, Monjazeb AM, Dave M, Ferrara JLM, Levine JE, Longo DL, Abedi M, Blazar BR, Murphy WJ. PMID: 33239390; PMCID: PMC8525601.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Phylogenomics and the Genetic Architecture of the Placental Mammal Radiation. Annu Rev Anim Biosci. 2021 02 16; 9:29-53.
Murphy WJ, Foley NM, Bredemeyer KR, Gatesy J, Springer MS. PMID: 33228377.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages. Genome Res. 2020 12; 30(12):1716-1726.
Hughes JF, Skaletsky H, Pyntikova T, Koutseva N, Raudsepp T, Brown LG, Bellott DW, Cho TJ, Dugan-Rocha S, Khan Z, Kremitzki C, Fronick C, Graves-Lindsay TA, Fulton L, Warren WC, Wilson RK, Owens E, Womack JE, Murphy WJ, Muzny DM, Worley KC, Chowdhary BP, Gibbs RA, Page DC. PMID: 33208454; PMCID: PMC7706723.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas. J Immunother Cancer. 2020 11; 8(2).
Judge SJ, Darrow MA, Thorpe SW, Gingrich AA, O'Donnell EF, Bellini AR, Sturgill IR, Vick LV, Dunai C, Stoffel KM, Lyu Y, Chen S, Cho M, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 33158916; PMCID: PMC7651745.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment. Front Immunol. 2020; 11:590568.
Le CT, Khuat LT, Caryotakis SE, Wang M, Dunai C, Nguyen AV, Vick LV, Stoffel KM, Blazar BR, Monjazeb AM, Murphy WJ, Soulika AM. PMID: 33193426; PMCID: PMC7658608.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation. Cancers (Basel). 2020 Oct 29; 12(11).
Alvarez M, Dunai C, Khuat LT, Aguilar EG, Barao I, Murphy WJ. PMID: 33138229; PMCID: PMC7692743.
View in:
PubMed Mentions:
5
-
A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism. PLoS Genet. 2020 10; 16(10):e1008926.
Buckley RM, Davis BW, Brashear WA, Farias FHG, Kuroki K, Graves T, Hillier LW, Kremitzki M, Li G, Middleton RP, Minx P, Tomlinson C, Lyons LA, Murphy WJ, Warren WC. PMID: 33090996; PMCID: PMC7581003.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansAnimals
-
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. Nat Commun. 2020 09 14; 11(1):4591.
Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ. PMID: 32929084; PMCID: PMC7490264.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
-
Minimal PD-1 expression in mouse and human NK cells under diverse conditions. J Clin Invest. 2020 06 01; 130(6):3051-3068.
Judge SJ, Dunai C, Aguilar EG, Vick SC, Sturgill IR, Khuat LT, Stoffel KM, Van Dyke J, Longo DL, Darrow MA, Anderson SK, Blazar BR, Monjazeb AM, Serody JS, Canter RJ, Murphy WJ. PMID: 32134744; PMCID: PMC7260004.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansAnimalsCells
-
Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD. Nat Rev Clin Oncol. 2020 08; 17(8):475-492.
Blazar BR, Hill GR, Murphy WJ. PMID: 32313224; PMCID: PMC7901860.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer. PLoS One. 2020; 15(2):e0224775.
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ. PMID: 32084139; PMCID: PMC7034869.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCellsCTClinical Trials
-
Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence. Front Cell Infect Microbiol. 2020; 10:49.
Judge SJ, Murphy WJ, Canter RJ. PMID: 32117816; PMCID: PMC7031155.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
-
Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease. Blood. 2020 01 02; 135(1):28-40.
Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, Murphy WJ, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Dahlberg C, Miller AT, Blazar BR. PMID: 31697815; PMCID: PMC6940197.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Evolutionary Models for the Diversification of Placental Mammals Across the KPg Boundary. Front Genet. 2019; 10:1241.
Springer MS, Foley NM, Brady PL, Gatesy J, Murphy WJ. PMID: 31850081; PMCID: PMC6896846.
View in:
PubMed Mentions:
19
-
Moving forward to address key unanswered questions on targeting PD-1/PD-L1 in cancer: limitations in preclinical models and the need to incorporate human modifying factors. J Immunother Cancer. 2019 11 07; 7(1):291.
Le CT, Murphy WJ. PMID: 31699145; PMCID: PMC6839253.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD. Blood. 2019 11 07; 134(19):1670-1682.
Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR. PMID: 31533918; PMCID: PMC6871306.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. JCI Insight. 2019 10 03; 4(19).
Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR. PMID: 31578305; PMCID: PMC6795410.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway. JCI Insight. 2019 06 18; 5.
Alvarez M, Simonetta F, Baker J, Pierini A, Wenokur AS, Morrison AR, Murphy WJ, Negrin RS. PMID: 31211693; PMCID: PMC6675585.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
-
Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma. Vet Comp Oncol. 2019 Sep; 17(3):242-252.
Withers SS, York D, Choi JW, Woolard KD, Laufer-Amorim R, Sparger EE, Burton JH, McSorley SJ, Monjazeb AM, Murphy WJ, Canter RJ, Rebhun RB. PMID: 30684301; PMCID: PMC6658355.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy. JAMA. 2019 Apr 02; 321(13):1247-1248.
Murphy WJ, Longo DL. PMID: 30882850.
View in:
PubMed Mentions:
50 Fields:
Translation:
Humans
-
Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease. Am J Transplant. 2019 06; 19(6):1820-1830.
Paz K, Flynn R, Du J, Tannheimer S, Johnson AJ, Dong S, Stark AK, Okkenhaug K, Panoskaltsis-Mortari A, Sage PT, Sharpe AH, Luznik L, Ritz J, Soiffer RJ, Cutler CS, Koreth J, Antin JH, Miklos DB, MacDonald KP, Hill GR, Maillard I, Serody JS, Murphy WJ, Munn DH, Feser C, Zaiken M, Vanhaesebroeck B, Turka LA, Byrd JC, Blazar BR. PMID: 30748099; PMCID: PMC6538456.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. J Immunol. 2019 05 01; 202(9):2795-2805.
Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR. PMID: 30885956; PMCID: PMC6478543.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Comparative Phylogeography of Forest-Dependent Mammals Reveals Paleo-Forest Corridors throughout Sundaland. J Hered. 2019 03 05; 110(2):158-172.
Mason VC, Helgen KM, Murphy WJ. PMID: 30247638.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. Cancers (Basel). 2019 Jan 14; 11(1).
Luna JI, Grossenbacher SK, Sturgill IR, Ames E, Judge SJ, Bouzid LA, Darrow MA, Murphy WJ, Canter RJ. PMID: 30646520; PMCID: PMC6356940.
View in:
PubMed Mentions:
12
-
The complicated effects of obesity on cancer and immunotherapy. Immunotherapy. 2019 01; 11(1):11-14.
Wang Z, Monjazeb AM, Murphy WJ. PMID: 30702013.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
-
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. Nat Med. 2019 01; 25(1):141-151.
Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. PMID: 30420753; PMCID: PMC6324991.
View in:
PubMed Mentions:
369 Fields:
Translation:
HumansAnimalsCells
-
Evolutionary conservation of Y Chromosome ampliconic gene families despite extensive structural variation. Genome Res. 2018 12; 28(12):1841-1851.
Brashear WA, Raudsepp T, Murphy WJ. PMID: 30381290; PMCID: PMC6280758.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease. Blood. 2019 01 03; 133(1):94-99.
Paz K, Flynn R, Du J, Qi J, Luznik L, Maillard I, MacDonald KP, Hill GR, Serody JS, Murphy WJ, Sage PT, Sharpe AH, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Bradner JE, Melnick AM, Blazar BR. PMID: 30279226; PMCID: PMC6318432.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Association of macrophage and lymphocyte infiltration with outcome in canine osteosarcoma. Vet Comp Oncol. 2019 Mar; 17(1):49-60.
Withers SS, Skorupski KA, York D, Choi JW, Woolard KD, Laufer-Amorim R, Sparger EE, Rodriguez CO, McSorley SJ, Monjazeb AM, Murphy WJ, Canter RJ, Rebhun RB. PMID: 30156029; PMCID: PMC6363827.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell. J Clin Invest. 2018 10 01; 128(10):4251-4253.
Dunai C, Murphy WJ. PMID: 30198909; PMCID: PMC6159962.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
A possible new pathway in natural killer cell activation also reveals the difficulty in determining human NK cell function in cancer. J Immunother Cancer. 2018 08 07; 6(1):79.
Canter RJ, Murphy WJ. PMID: 30086799; PMCID: PMC6081859.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Horse Y chromosome assembly displays unique evolutionary features and putative stallion fertility genes. Nat Commun. 2018 07 27; 9(1):2945.
Janecka JE, Davis BW, Ghosh S, Paria N, Das PJ, Orlando L, Schubert M, Nielsen MK, Stout TAE, Brashear W, Li G, Johnson CD, Metz RP, Zadjali AMA, Love CC, Varner DD, Bellott DW, Murphy WJ, Chowdhary BP, Raudsepp T. PMID: 30054462; PMCID: PMC6063916.
View in:
PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
-
Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. Theranostics. 2018; 8(13):3611-3628.
Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW. PMID: 30026870; PMCID: PMC6037035.
View in:
PubMed Mentions:
45 Fields:
Translation:
Animals
-
The Birth and Death of Olfactory Receptor Gene Families in Mammalian Niche Adaptation. Mol Biol Evol. 2018 06 01; 35(6):1390-1406.
Hughes GM, Boston ESM, Finarelli JA, Murphy WJ, Higgins DG, Teeling EC. PMID: 29562344; PMCID: PMC5967467.
View in:
PubMed Mentions:
49 Fields:
Translation:
Animals
-
Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. Dev Comp Immunol. 2018 10; 87:64-74.
Withers SS, Moore PF, Chang H, Choi JW, McSorley SJ, Kent MS, Monjazeb AM, Canter RJ, Murphy WJ, Sparger EE, Rebhun RB. PMID: 29859828; PMCID: PMC6197816.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Obesity as an immune-modifying factor in cancer immunotherapy. J Leukoc Biol. 2018 09; 104(3):487-497.
Canter RJ, Le CT, Beerthuijzen JMT, Murphy WJ. PMID: 29762866; PMCID: PMC6113103.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
-
Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site. Int J Radiat Oncol Biol Phys. 2018 08 01; 101(5):1259-1270.
McGee HM, Daly ME, Azghadi S, Stewart SL, Oesterich L, Schlom J, Donahue R, Schoenfeld JD, Chen Q, Rao S, Fragoso RC, Valicenti RK, Canter RJ, Maverakis EM, Murphy WJ, Kelly K, Monjazeb AM. PMID: 29891204; PMCID: PMC6364565.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Improving classification of melanocytic nevi: Association of BRAF V600E expression with distinct histomorphologic features. J Am Acad Dermatol. 2018 Aug; 79(2):221-229.
Kiuru M, Tartar DM, Qi L, Chen D, Yu L, Konia T, McPherson JD, Murphy WJ, Fung MA. PMID: 29653212; PMCID: PMC6090558.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Obesity induced T cell dysfunction and implications for cancer immunotherapy. Curr Opin Immunol. 2018 04; 51:181-186.
Aguilar EG, Murphy WJ. PMID: 29655021; PMCID: PMC6338436.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
-
Olfaction written in bone: cribriform plate size parallels olfactory receptor gene repertoires in Mammalia. Proc Biol Sci. 2018 03 14; 285(1874).
Bird DJ, Murphy WJ, Fox-Rosales L, Hamid I, Eagle RA, Van Valkenburgh B. PMID: 29540522; PMCID: PMC5879636.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Donor HSCs with a preexisting ASXL1-mutation led to the development of FLT3-ITD positive AML in the donor and FLT3-ITD negative AML in the recipient after unrelated transplant. Bone Marrow Transplant. 2018 04; 53(4):499-502.
Liu Z, Liu H, Shi M, Ahmed HAW, Huo L, Zhang Y, Kong D, Wen M, Wang F, Chen M, Murphy WJ, Sun K. PMID: 29330388.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Appropriate fossil calibrations and tree constraints uphold the Mesozoic divergence of solenodons from other extant mammals. Mol Phylogenet Evol. 2018 04; 121:158-165.
Springer MS, Murphy WJ, Roca AL. PMID: 29331683.
View in:
PubMed Mentions:
12 Fields:
Translation:
Animals
-
Making a Better Hematopoietic Stem Cell - Timing Is Everything. N Engl J Med. 2018 01 04; 378(1):89-91.
Murphy WJ. PMID: 29298159.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas. J Surg Res. 2018 03; 223:207-214.
Henderson T, Chen M, Darrow MA, Li CS, Chiu CL, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 29433875; PMCID: PMC5812363.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial. J Immunother Cancer. 2017 Dec 19; 5(1):98.
Canter RJ, Grossenbacher SK, Foltz JA, Sturgill IR, Park JS, Luna JI, Kent MS, Culp WTN, Chen M, Modiano JF, Monjazeb AM, Lee DA, Murphy WJ. PMID: 29254507; PMCID: PMC5735903.
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Range-Wide Snow Leopard Phylogeography Supports Three Subspecies. J Hered. 2017 Sep 01; 108(6):597-607.
Janecka JE, Zhang Y, Li D, Munkhtsog B, Bayaraa M, Galsandorj N, Wangchuk TR, Karmacharya D, Li J, Lu Z, Uulu KZ, Gaur A, Kumar S, Kumar K, Hussain S, Muhammad G, Jevit M, Hacker C, Burger P, Wultsch C, Janecka MJ, Helgen K, Murphy WJ, Jackson R. PMID: 28498961.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Genome-wide signatures of complex introgression and adaptive evolution in the big cats. Sci Adv. 2017 07; 3(7):e1700299.
Figueiró HV, Li G, Trindade FJ, Assis J, Pais F, Fernandes G, Santos SHD, Hughes GM, Komissarov A, Antunes A, Trinca CS, Rodrigues MR, Linderoth T, Bi K, Silveira L, Azevedo FCC, Kantek D, Ramalho E, Brassaloti RA, Villela PMS, Nunes ALV, Teixeira RHF, Morato RG, Loska D, Saragüeta P, Gabaldón T, Teeling EC, O'Brien SJ, Nielsen R, Coutinho LL, Oliveira G, Murphy WJ, Eizirik E. PMID: 28776029; PMCID: PMC5517113.
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PubMed Mentions:
56 Fields:
Translation:
Animals
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Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment. Am J Pathol. 2017 Aug; 187(8):1800-1813.
Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY. PMID: 28711154; PMCID: PMC5530909.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Therapeutic Efficacy of Fresh, Allogeneic Mesenchymal Stem Cells for Severe Refractory Feline Chronic Gingivostomatitis. Stem Cells Transl Med. 2017 08; 6(8):1710-1722.
Arzi B, Clark KC, Sundaram A, Spriet M, Verstraete FJM, Walker NJ, Loscar MR, Fazel N, Murphy WJ, Vapniarsky N, Borjesson DL. PMID: 28618186; PMCID: PMC5689767.
View in:
PubMed Mentions:
44 Fields:
Translation:
Animals
-
Licensing delineates helper and effector NK cell subsets during viral infection. JCI Insight. 2017 May 18; 2(10).
Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ. PMID: 28515356; PMCID: PMC5436543.
View in:
PubMed Mentions:
16 Fields:
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Leveraging natural killer cells for cancer immunotherapy. Immunotherapy. 2017 05; 9(6):487-497.
Grossenbacher SK, Aguilar EG, Murphy WJ. PMID: 28472904; PMCID: PMC5941700.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control. Int J Radiat Oncol Biol Phys. 2017 10 01; 99(2):362-373.
Baird JR, Monjazeb AM, Shah O, McGee H, Murphy WJ, Crittenden MR, Gough MJ. PMID: 28871985; PMCID: PMC5604475.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy. J Immunother Cancer. 2017; 5:33.
Sckisel GD, Mirsoian A, Minnar CM, Crittenden M, Curti B, Chen JQ, Blazar BR, Borowsky AD, Monjazeb AM, Murphy WJ. PMID: 28428882; PMCID: PMC5394626.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols. JCI Insight. 2017 03 23; 2(6):e90521.
Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW. PMID: 28352658; PMCID: PMC5358490.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017 03 20; 8(1):69.
Clark KC, Fierro FA, Ko EM, Walker NJ, Arzi B, Tepper CG, Dahlenburg H, Cicchetto A, Kol A, Marsh L, Murphy WJ, Fazel N, Borjesson DL. PMID: 28320483; PMCID: PMC5360077.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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The proportion of circulating CD45RO+CD8+ memory T cells is correlated with clinical response in melanoma patients treated with ipilimumab. Eur J Cancer. 2017 04; 75:268-279.
Tietze JK, Angelova D, Heppt MV, Reinholz M, Murphy WJ, Spannagl M, Ruzicka T, Berking C. PMID: 28242504.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy. Expert Opin Biol Ther. 2017 03; 17(3):313-324.
Luna JI, Grossenbacher SK, Murphy WJ, Canter RJ. PMID: 27960589; PMCID: PMC5311007.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Canine cancer immunotherapy studies: linking mouse and human. J Immunother Cancer. 2016; 4:97.
Park JS, Withers SS, Modiano JF, Kent MS, Chen M, Luna JI, Culp WTN, Sparger EE, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 28031824; PMCID: PMC5171656.
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PubMed Mentions:
62 Fields:
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Being "penny-wise but pound foolish" in cancer immunotherapy research: the urgent need for mouse cancer models to reflect human modifying factors. J Immunother Cancer. 2016; 4:88.
Murphy WJ. PMID: 28031818; PMCID: PMC5170894.
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PubMed Mentions:
2 Fields:
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Therapeutic Effects of a NEDD8-Activating Enzyme Inhibitor, Pevonedistat, on Sclerodermatous Graft-versus-Host Disease in Mice. Biol Blood Marrow Transplant. 2017 01; 23(1):30-37.
Pai CS, Khuat LT, Chen M, Murphy WJ, Abedi M. PMID: 27815049; PMCID: PMC5469294.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Waking the undead: Implications of a soft explosive model for the timing of placental mammal diversification. Mol Phylogenet Evol. 2017 01; 106:86-102.
Springer MS, Emerling CA, Meredith RW, Janecka JE, Eizirik E, Murphy WJ. PMID: 27659724.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Resolution of a concatenation/coalescence kerfuffle: partitioned coalescence support and a robust family-level tree for Mammalia. Cladistics. 2017 Jun; 33(3):295-332.
Gatesy J, Meredith RW, Janecka JE, Simmons MP, Murphy WJ, Springer MS. PMID: 34715726.
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PubMed Mentions:
11 Fields:
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Genomic analysis reveals hidden biodiversity within colugos, the sister group to primates. Sci Adv. 2016 08; 2(8):e1600633.
Mason VC, Li G, Minx P, Schmitz J, Churakov G, Doronina L, Melin AD, Dominy NJ, Lim NT, Springer MS, Wilson RK, Warren WC, Helgen KM, Murphy WJ. PMID: 27532052; PMCID: PMC4980104.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Immunoregulatory pathways following strong inflammatory processes markedly impair CD4+ T cell responses. Hum Vaccin Immunother. 2016 09; 12(9):2249-52.
Minnar CM, Murphy WJ. PMID: 27409155; PMCID: PMC5027755.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner. Blood. 2016 08 18; 128(7):1013-7.
McDonald-Hyman C, Flynn R, Panoskaltsis-Mortari A, Peterson N, MacDonald KP, Hill GR, Luznik L, Serody JS, Murphy WJ, Maillard I, Munn DH, Turka LA, Koreth J, Cutler CS, Soiffer RJ, Antin JH, Ritz J, Blazar BR. PMID: 27385791; PMCID: PMC4990850.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016 07 01; 126(7):2642-60.
Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR. PMID: 27294527; PMCID: PMC4922691.
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PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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A High-Resolution SNP Array-Based Linkage Map Anchors a New Domestic Cat Draft Genome Assembly and Provides Detailed Patterns of Recombination. G3 (Bethesda). 2016 06 01; 6(6):1607-16.
Li G, Hillier LW, Grahn RA, Zimin AV, David VA, Menotti-Raymond M, Middleton R, Hannah S, Hendrickson S, Makunin A, O'Brien SJ, Minx P, Wilson RK, Lyons LA, Warren WC, Murphy WJ. PMID: 27172201; PMCID: PMC4889657.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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High fluence light emitting diode-generated red light modulates characteristics associated with skin fibrosis. J Biophotonics. 2016 12; 9(11-12):1167-1179.
Mamalis A, Koo E, Garcha M, Murphy WJ, Isseroff RR, Jagdeo J. PMID: 27174640; PMCID: PMC5107354.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Mitogenomic sequences support a north-south subspecies subdivision within Solenodon paradoxus. Mitochondrial DNA A DNA Mapp Seq Anal. 2017 09; 28(5):662-670.
Brandt AL, Grigorev K, Afanador-Hernández YM, Paulino LA, Murphy WJ, Núñez A, Komissarov A, Brandt JR, Dobrynin P, Hernández-Martich JD, María R, O'Brien SJ, Rodríguez LE, Martínez-Cruzado JC, Oleksyk TK, Roca AL. PMID: 27159724.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Natural killer cell immunotherapy to target stem-like tumor cells. J Immunother Cancer. 2016; 4:19.
Grossenbacher SK, Canter RJ, Murphy WJ. PMID: 27096096; PMCID: PMC4835831.
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PubMed Mentions:
28 Fields:
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Immune targeting of cancer stem cells in gastrointestinal oncology. J Gastrointest Oncol. 2016 Apr; 7(Suppl 1):S1-S10.
Canter RJ, Grossenbacher SK, Ames E, Murphy WJ. PMID: 27034806; PMCID: PMC4783622.
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PubMed Mentions:
6
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Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood. 2016 04 28; 127(17):2144-54.
Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, Aguilar EG, Murphy WJ, Maillard I, Munn D, Koreth J, Cutler CS, Antin JH, Ritz J, Waksal SD, Zanin-Zhorov A, Blazar BR. PMID: 26983850; PMCID: PMC4850869.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies. Clin Cancer Res. 2016 Sep 01; 22(17):4328-40.
Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ. PMID: 26979392; PMCID: PMC5010514.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment. Blood. 2016 Mar 03; 127(9):1202-5.
Alvarez M, Sun K, Murphy WJ. PMID: 26738538; PMCID: PMC4778165.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Preclinical modeling of hematopoietic stem cell transplantation - advantages and limitations. FEBS J. 2016 05; 283(9):1595-606.
Stolfi JL, Pai CC, Murphy WJ. PMID: 26640088.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Therapeutic Efficacy of Fresh, Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats. Stem Cells Transl Med. 2016 Jan; 5(1):75-86.
Arzi B, Mills-Ko E, Verstraete FJ, Kol A, Walker NJ, Badgley MR, Fazel N, Murphy WJ, Vapniarsky N, Borjesson DL. PMID: 26582907; PMCID: PMC4704876.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Phylogenomic evidence for ancient hybridization in the genomes of living cats (Felidae). Genome Res. 2016 Jan; 26(1):1-11.
Li G, Davis BW, Eizirik E, Murphy WJ. PMID: 26518481; PMCID: PMC4691742.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity. Cancer Res. 2015 Dec 15; 75(24):5260-72.
Shanker A, Pellom ST, Dudimah DF, Thounaojam MC, de Kluyver RL, Brooks AD, Yagita H, McVicar DW, Murphy WJ, Longo DL, Sayers TJ. PMID: 26494122; PMCID: PMC4681610.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery. J Control Release. 2015 Dec 28; 220(Pt A):253-264.
Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW. PMID: 26471394; PMCID: PMC4688109.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration. PLoS One. 2015; 10(10):e0140628.
Mamalis A, Koo E, Isseroff RR, Murphy W, Jagdeo J. PMID: 26488596; PMCID: PMC4619307.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy. Cancer Immunol Immunother. 2015 Dec; 64(12):1541-52.
Sckisel GD, Mirsoian A, Bouchlaka MN, Tietze JK, Chen M, Blazar BR, Murphy WJ. PMID: 26423422; PMCID: PMC4782757.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016 06 02; 35(22):2932-47.
Yokdang N, Hatakeyama J, Wald JH, Simion C, Tellez JD, Chang DZ, Swamynathan MM, Chen M, Murphy WJ, Carraway Iii KL, Sweeney C. PMID: 26387542; PMCID: PMC4805527.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype. J Immunol. 2015 Oct 15; 195(8):4010-9.
Ames E, Canter RJ, Grossenbacher SK, Mac S, Chen M, Smith RC, Hagino T, Perez-Cunningham J, Sckisel GD, Urayama S, Monjazeb AM, Fragoso RC, Sayers TJ, Murphy WJ. PMID: 26363055; PMCID: PMC4781667.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer. Oncoimmunology. 2016 Feb; 5(2):e1075114.
Mall C, Sckisel GD, Proia DA, Mirsoian A, Grossenbacher SK, Pai CS, Chen M, Monjazeb AM, Kelly K, Blazar BR, Murphy WJ. PMID: 27057446; PMCID: PMC4801432.
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PubMed Mentions:
28 Fields:
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GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 2015 Sep 24; 126(13):1621-8.
Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, Blazar BR. PMID: 26265697; PMCID: PMC4582338.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Models to Study NK Cell Biology and Possible Clinical Application. Curr Protoc Immunol. 2015 Aug 03; 110:14.37.1-14.37.14.
Zamora AE, Grossenbacher SK, Aguilar EG, Murphy WJ. PMID: 26237009; PMCID: PMC4772895.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity. Immunity. 2015 Aug 18; 43(2):240-50.
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. PMID: 26231116; PMCID: PMC4770886.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Enhanced targeting of stem-like solid tumor cells with radiation and natural killer cells. Oncoimmunology. 2015 Sep; 4(9):e1036212.
Ames E, Canter RJ, Grossenbacher SK, Mac S, Smith RC, Monjazeb AM, Chen M, Murphy WJ. PMID: 26405602; PMCID: PMC4570100.
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PubMed Mentions:
49 Fields:
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Interordinal gene capture, the phylogenetic position of Steller's sea cow based on molecular and morphological data, and the macroevolutionary history of Sirenia. Mol Phylogenet Evol. 2015 Oct; 91:178-93.
Springer MS, Signore AV, Paijmans JL, Vélez-Juarbe J, Domning DP, Bauer CE, He K, Crerar L, Campos PF, Murphy WJ, Meredith RW, Gatesy J, Willerslev E, MacPhee RD, Hofreiter M, Campbell KL. PMID: 26050523.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
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Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 2015 Jun 25; 125(26):4085-94.
Flynn R, Allen JL, Luznik L, MacDonald KP, Paz K, Alexander KA, Vulic A, Du J, Panoskaltsis-Mortari A, Taylor PA, Poe JC, Serody JS, Murphy WJ, Hill GR, Maillard I, Koreth J, Cutler CS, Soiffer RJ, Antin JH, Ritz J, Chao NJ, Clynes RA, Sarantopoulos S, Blazar BR. PMID: 25852057; PMCID: PMC4481596.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Attenuated age-impact on systemic inflammatory markers in the presence of a metabolic burden. PLoS One. 2015; 10(3):e0121947.
Erdembileg A, Mirsoian A, Enkhmaa B, Zhang W, Beckett LA, Murphy WJ, Berglund LF. PMID: 25815855; PMCID: PMC4376898.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality. Blood. 2015 05 21; 125(21):3335-46.
Veenstra RG, Flynn R, Kreymborg K, McDonald-Hyman C, Saha A, Taylor PA, Osborn MJ, Panoskaltsis-Mortari A, Schmitt-Graeff A, Lieberknecht E, Murphy WJ, Serody JS, Munn DH, Freeman GJ, Allison JP, Mak TW, van den Brink M, Zeiser R, Blazar BR. PMID: 25814530; PMCID: PMC4440885.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Reprint of: Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biol Blood Marrow Transplant. 2015 Feb; 21(2 Suppl):S19-24.
Boeckh M, Murphy WJ, Peggs KS. PMID: 25620648.
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PubMed Mentions:
8 Fields:
-
Obesity and cancer immunotherapy toxicity. Immunotherapy. 2015; 7(4):319-22.
Mirsoian A, Murphy WJ. PMID: 25917623; PMCID: PMC4787259.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biol Blood Marrow Transplant. 2015 Jan; 21(1):24-9.
Boeckh M, Murphy WJ, Peggs KS. PMID: 25452035.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17230-5.
Montague MJ, Li G, Gandolfi B, Khan R, Aken BL, Searle SM, Minx P, Hillier LW, Koboldt DC, Davis BW, Driscoll CA, Barr CS, Blackistone K, Quilez J, Lorente-Galdos B, Marques-Bonet T, Alkan C, Thomas GW, Hahn MW, Menotti-Raymond M, O'Brien SJ, Wilson RK, Lyons LA, Murphy WJ, Warren WC. PMID: 25385592; PMCID: PMC4260561.
View in:
PubMed Mentions:
161 Fields:
Translation:
AnimalsCells
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Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. J Exp Med. 2014 Nov 17; 211(12):2373-83.
Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ. PMID: 25366964; PMCID: PMC4235633.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma. BMC Cancer. 2014 Oct 10; 14:756.
Canter RJ, Ames E, Mac S, Grossenbacher SK, Chen M, Li CS, Borys D, Smith RC, Tellez J, Sayers TJ, Monjazeb AM, Murphy WJ. PMID: 25301268; PMCID: PMC4200119.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. J Clin Invest. 2014 Nov; 124(11):4867-76.
Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR. PMID: 25271622; PMCID: PMC4347242.
View in:
PubMed Mentions:
105 Fields:
Translation:
Animals
-
Bringing out the DCs' softer side in GVHD. Blood. 2014 Sep 18; 124(12):1852-3.
Murphy WJ. PMID: 25606629.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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The authors' reply. Transplantation. 2014 Sep 15; 98(5):e39-40.
Ames E, Murphy WJ. PMID: 25171530; PMCID: PMC4343530.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Using a web-based nutrition algorithm in hemodialysis patients. J Ren Nutr. 2015 Jan; 25(1):6-16.
Steiber AL, León JB, Hand RK, Murphy WJ, Fouque D, Parrott JS, Kalantar-Zadeh K, Cuppari L. PMID: 25193109.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. PLoS One. 2014; 9(8):e102709.
Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. PMID: 25119341; PMCID: PMC4131875.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels. Biol Blood Marrow Transplant. 2014 Dec; 20(12):1899-904.
Pai CC, Hsiao HH, Sun K, Chen M, Hagino T, Tellez J, Mall C, Blazar BR, Monjazeb A, Abedi M, Murphy WJ. PMID: 25064746; PMCID: PMC4254314.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Treatment of chronic graft-versus-host disease with bortezomib. Blood. 2014 Sep 04; 124(10):1677-88.
Pai CC, Chen M, Mirsoian A, Grossenbacher SK, Tellez J, Ames E, Sun K, Jagdeo J, Blazar BR, Murphy WJ, Abedi M. PMID: 25009225; PMCID: PMC4155274.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCellsCTClinical Trials
-
Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells. J Immunol. 2014 Aug 15; 193(4):1709-16.
Alvarez M, Bouchlaka MN, Sckisel GD, Sungur CM, Chen M, Murphy WJ. PMID: 25000978; PMCID: PMC4241855.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Natural killer cell subsets differentially reject embryonic stem cells based on licensing. Transplantation. 2014 May 27; 97(10):992-8.
Perez-Cunningham J, Ames E, Smith RC, Peter AK, Naidu R, Nolta JA, Murphy WJ. PMID: 24704665.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 2014 Jun 19; 123(25):3988-98.
Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, Soiffer RJ, Antin JH, Ritz J, Dubovsky JA, Byrd JC, MacDonald KP, Hill GR, Blazar BR. PMID: 24820310; PMCID: PMC4064335.
View in:
PubMed Mentions:
127 Fields:
Translation:
AnimalsCells
-
Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy. J Immunol. 2014 Jun 15; 192(12):5821-9.
Weiss JM, Subleski JJ, Back T, Chen X, Watkins SK, Yagita H, Sayers TJ, Murphy WJ, Wiltrout RH. PMID: 24808361; PMCID: PMC4048774.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
-
A cluster of olfactory receptor genes linked to frugivory in bats. Mol Biol Evol. 2014 Apr; 31(4):917-27.
Hayden S, Bekaert M, Goodbla A, Murphy WJ, Dávalos LM, Teeling EC. PMID: 24441035.
View in:
PubMed Mentions:
31 Fields:
Translation:
Animals
-
Positive and negative regulation by NK cells in cancer. Crit Rev Oncog. 2014; 19(1-2):57-66.
Sungur CM, Murphy WJ. PMID: 24941373; PMCID: PMC4242411.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. Clin Exp Immunol. 2014 Jan; 175(1):79-91.
Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ. PMID: 23937663; PMCID: PMC3898557.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models. Oncoimmunology. 2013 Dec 01; 2(12):e27186.
Bouchlaka MN, Murphy WJ. PMID: 24498569; PMCID: PMC3909540.
View in:
PubMed Mentions:
14 Fields:
-
Cellular and molecular pathways in the tumor immunoenvironment: 3rd Cancer Immunotherapy and Immunomonitoring (CITIM) meeting, 22-25 April 2013, Krakow, Poland. Cancer Immunol Immunother. 2014 Jan; 63(1):73-80.
Shurin MR, Umansky V, Malyguine A, Hurwitz AA, Apte RN, Whiteside T, Jewett A, Thanavala Y, Murphy WJ. PMID: 24271210; PMCID: PMC7665797.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. J Exp Med. 2013 Oct 21; 210(11):2223-37.
Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. PMID: 24081947; PMCID: PMC3804937.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
-
The path(way) less traveled. Blood. 2013 Sep 19; 122(12):1996-7.
Abedi M, Murphy WJ. PMID: 24052539.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 2013 Oct 24; 122(17):3062-73.
Saha A, Aoyama K, Taylor PA, Koehn BH, Veenstra RG, Panoskaltsis-Mortari A, Munn DH, Murphy WJ, Azuma M, Yagita H, Fife BT, Sayegh MH, Najafian N, Socie G, Ahmed R, Freeman GJ, Sharpe AH, Blazar BR. PMID: 24030385; PMCID: PMC3811178.
View in:
PubMed Mentions:
100 Fields:
Translation:
AnimalsCells
-
Advantages and clinical applications of natural killer cells in cancer immunotherapy. Cancer Immunol Immunother. 2014 Jan; 63(1):21-8.
Ames E, Murphy WJ. PMID: 23989217; PMCID: PMC3880590.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
-
Technical comment on "The placental mammal ancestor and the post-K-Pg radiation of placentals". Science. 2013 Aug 09; 341(6146):613.
Springer MS, Meredith RW, Teeling EC, Murphy WJ. PMID: 23929967.
View in:
PubMed Mentions:
24 Fields:
Translation:
Animals
-
Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013 Oct; 19(10):1446-52.
Barao I, Wright PW, Sungur CM, Anderson SK, Redelman D, Murphy WJ. PMID: 23911940; PMCID: PMC3786177.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Immunoediting and antigen loss: overcoming the achilles heel of immunotherapy with antigen non-specific therapies. Front Oncol. 2013; 3:197.
Monjazeb AM, Zamora AE, Grossenbacher SK, Mirsoian A, Sckisel GD, Murphy WJ. PMID: 23898464; PMCID: PMC3724213.
View in:
PubMed Mentions:
24
-
Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses. Blood. 2013 Aug 22; 122(8):1518-21.
Sungur CM, Tang-Feldman YJ, Zamora AE, Alvarez M, Pomeroy C, Murphy WJ. PMID: 23818546; PMCID: PMC3750345.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 2013 Sep 19; 122(12):2125-34.
Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Socié G, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, Chandraratna RA, Dmitrovsky E, Guo Y, Noelle RJ, Blazar BR. PMID: 23814022; PMCID: PMC3778553.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Sci. 2013 Aug; 22(8):1078-86.
He W, Luo J, Bourguet F, Xing L, Yi SK, Gao T, Blanchette C, Henderson PT, Kuhn E, Malfatti M, Murphy WJ, Cheng RH, Lam KS, Coleman MA. PMID: 23754445; PMCID: PMC3832044.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
Comparative analysis of mammalian Y chromosomes illuminates ancestral structure and lineage-specific evolution. Genome Res. 2013 Sep; 23(9):1486-95.
Li G, Davis BW, Raudsepp T, Pearks Wilkerson AJ, Mason VC, Ferguson-Smith M, O'Brien PC, Waters PD, Murphy WJ. PMID: 23788650; PMCID: PMC3759724.
View in:
PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
-
Contrasting effects of anti-Ly49A due to MHC class I cis binding on NK cell-mediated allogeneic bone marrow cell resistance. J Immunol. 2013 Jul 15; 191(2):688-98.
Alvarez M, Sungur CM, Ames E, Anderson SK, Pomeroy C, Murphy WJ. PMID: 23752612; PMCID: PMC3733663.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Of mice and men. Biol Blood Marrow Transplant. 2013 Aug; 19(8):1140-1.
Murphy WJ. PMID: 23680473.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Murine natural killer cell licensing and regulation by T regulatory cells in viral responses. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7401-6.
Sungur CM, Tang-Feldman YJ, Ames E, Alvarez M, Chen M, Longo DL, Pomeroy C, Murphy WJ. PMID: 23589894; PMCID: PMC3645578.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Using Illumina next generation sequencing technologies to sequence multigene families in de novo species. Mol Ecol Resour. 2013 May; 13(3):510-21.
Hughes GM, Gang L, Murphy WJ, Higgins DG, Teeling EC. PMID: 23480365.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Impact of Obesity and Aging on the Tumor Immuno-Environment. . 2013 Jan 1; 223-250.
Mirsoian MA, Sckisel SG, Zamora ZA, Murphy MW. .
View in:
Publisher Site Mentions:
-
Utilization of mouse models to decipher natural killer cell biology and potential clinical applications. Hematology Am Soc Hematol Educ Program. 2013; 2013:227-33.
Sungur CM, Murphy WJ. PMID: 24319185.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
-
Macroevolutionary dynamics and historical biogeography of primate diversification inferred from a species supermatrix. PLoS One. 2012; 7(11):e49521.
Springer MS, Meredith RW, Gatesy J, Emerling CA, Park J, Rabosky DL, Stadler T, Steiner C, Ryder OA, Janecka JE, Fisher CA, Murphy WJ. PMID: 23166696; PMCID: PMC3500307.
View in:
PubMed Mentions:
113 Fields:
Translation:
Animals
-
Mechanical disruption of tumors by iron particles and magnetic field application results in increased anti-tumor immune responses. PLoS One. 2012; 7(10):e48049.
Bouchlaka MN, Sckisel GD, Wilkins D, Maverakis E, Monjazeb AM, Fung M, Welniak L, Redelman D, Fuchs A, Evrensel CA, Murphy WJ. PMID: 23133545; PMCID: PMC3485005.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells. Oncoimmunology. 2012 Oct 01; 1(7):1208-1210.
Sckisel GD, Murphy WJ. PMID: 23170282; PMCID: PMC3494648.
View in:
PubMed Mentions:
1 Fields:
-
IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation. J Immunol. 2012 Aug 15; 189(4):2033-42.
Sun K, Hsiao HH, Li M, Ames E, Bouchlaka M, Welniak LA, Hagino T, Jagdeo J, Pai CC, Chen M, Blazar BR, Abedi M, Murphy WJ. PMID: 22778394; PMCID: PMC3509544.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
The role of antigen-specific and non-specific immunotherapy in the treatment of cancer. J Immunotoxicol. 2012 Jul-Sep; 9(3):248-58.
Monjazeb AM, Hsiao HH, Sckisel GD, Murphy WJ. PMID: 22734880.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol. 2012 May 11; 12(6):443-58.
Blazar BR, Murphy WJ, Abedi M. PMID: 22576252; PMCID: PMC3552454.
View in:
PubMed Mentions:
417 Fields:
Translation:
HumansAnimalsCells
-
Autoimmune T cells lured to a FASL web of death by MSCs. Cell Stem Cell. 2012 May 04; 10(5):485-7.
Murphy WJ, Nolta JA. PMID: 22560070.
View in:
PubMed Mentions:
4 Fields:
-
Hearing threshold levels at age 70 years (65-74 years) in the unscreened older adult population of the United States, 1959-1962 and 1999-2006. Ear Hear. 2012 May-Jun; 33(3):437-40.
Hoffman HJ, Dobie RA, Ko CW, Themann CL, Murphy WJ. PMID: 22080933.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy. Blood. 2012 Mar 29; 119(13):3073-83.
Tietze JK, Wilkins DE, Sckisel GD, Bouchlaka MN, Alderson KL, Weiss JM, Ames E, Bruhn KW, Craft N, Wiltrout RH, Longo DL, Lanier LL, Blazar BR, Redelman D, Murphy WJ. PMID: 22251483; PMCID: PMC3321869.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
-
NK cells--from bench to clinic. Biol Blood Marrow Transplant. 2012 Jan; 18(1 Suppl):S2-7.
Murphy WJ, Parham P, Miller JS. PMID: 22226108; PMCID: PMC3260456.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensing. Blood. 2012 Feb 09; 119(6):1590-8.
Sun K, Alvarez M, Ames E, Barao I, Chen M, Longo DL, Redelman D, Murphy WJ. PMID: 22184406; PMCID: PMC3286220.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
Defining the critical hurdles in cancer immunotherapy. J Transl Med. 2011 Dec 14; 9:214.
Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG, Finke JH, Galon J, Gollob JA, Gouttefangeas C, Grizzi F, Guida M, Håkansson L, Hege K, Herberman RB, Hodi FS, Hoos A, Huber C, Hwu P, Imai K, Jaffee EM, Janetzki S, June CH, Kalinski P, Kaufman HL, Kawakami K, Kawakami Y, Keilholtz U, Khleif SN, Kiessling R, Kotlan B, Kroemer G, Lapointe R, Levitsky HI, Lotze MT, Maccalli C, Maio M, Marschner JP, Mastrangelo MJ, Masucci G, Melero I, Melief C, Murphy WJ, Nelson B, Nicolini A, Nishimura MI, Odunsi K, Ohashi PS, O'Donnell-Tormey J, Old LJ, Ottensmeier C, Papamichail M, Parmiani G, Pawelec G, Proietti E, Qin S, Rees R, Ribas A, Ridolfi R, Ritter G, Rivoltini L, Romero PJ, Salem ML, Scheper RJ, Seliger B, Sharma P, Shiku H, Singh-Jasuja H, Song W, Straten PT, Tahara H, Tian Z, van Der Burg SH, von Hoegen P, Wang E, Welters MJ, Winter H, Withington T, Wolchok JD, Xiao W, Zitvogel L, Zwierzina H, Marincola FM, Gajewski TF, Wigginton JM, Disis ML. PMID: 22168571; PMCID: PMC3338100.
View in:
PubMed Mentions:
72 Fields:
Translation:
Humans
-
The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice. Biol Blood Marrow Transplant. 2012 Mar; 18(3):396-405.
Ames E, Harouna S, Meyer C, Welniak LA, Murphy WJ. PMID: 22100978; PMCID: PMC3502000.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans. Blood. 2012 Feb 09; 119(6):1570-80.
Srinivasan M, Flynn R, Price A, Ranger A, Browning JL, Taylor PA, Ritz J, Antin JH, Murphy WJ, Luznik L, Shlomchik MJ, Panoskaltsis-Mortari A, Blazar BR. PMID: 22072556; PMCID: PMC3286218.
View in:
PubMed Mentions:
140 Fields:
Translation:
HumansAnimalsCells
-
Antigen-specific versus antigen-nonspecific immunotherapeutic approaches for human melanoma: the need for integration for optimal efficacy? Int Rev Immunol. 2011 Oct-Dec; 30(5-6):238-93.
Tietze JK, Sckisel GD, Hsiao HH, Murphy WJ. PMID: 22053969.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Impacts of the Cretaceous Terrestrial Revolution and KPg extinction on mammal diversification. Science. 2011 Oct 28; 334(6055):521-4.
Meredith RW, Janecka JE, Gatesy J, Ryder OA, Fisher CA, Teeling EC, Goodbla A, Eizirik E, Simão TL, Stadler T, Rabosky DL, Honeycutt RL, Flynn JJ, Ingram CM, Steiner C, Williams TL, Robinson TJ, Burk-Herrick A, Westerman M, Ayoub NA, Springer MS, Murphy WJ. PMID: 21940861.
View in:
PubMed Mentions:
505 Fields:
Translation:
Animals
-
The historical biogeography of Mammalia. Philos Trans R Soc Lond B Biol Sci. 2011 Sep 12; 366(1577):2478-502.
Springer MS, Meredith RW, Janecka JE, Murphy WJ. PMID: 21807730; PMCID: PMC3138613.
View in:
PubMed Mentions:
40 Fields:
Translation:
Animals
-
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2011 Dec; 17(12):1754-64.
Barao I, Alvarez M, Redelman D, Weiss JM, Ortaldo JR, Wiltrout RH, Murphy WJ. PMID: 21906575; PMCID: PMC3506429.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Efficient cross-species capture hybridization and next-generation sequencing of mitochondrial genomes from noninvasively sampled museum specimens. Genome Res. 2011 Oct; 21(10):1695-704.
Mason VC, Li G, Helgen KM, Murphy WJ. PMID: 21880778; PMCID: PMC3202286.
View in:
PubMed Mentions:
44 Fields:
Translation:
Animals
-
Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC. Blood. 2011 Jun 30; 117(26):7032-41.
Barao I, Alvarez M, Ames E, Orr MT, Stefanski HE, Blazar BR, Lanier LL, Anderson SK, Redelman D, Murphy WJ. PMID: 21498673; PMCID: PMC3143551.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood. 2011 Apr 28; 117(17):4501-10.
Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy WJ, Azuma M, Anderson AC, Kuchroo VK, Blazar BR. PMID: 21385853; PMCID: PMC3099570.
View in:
PubMed Mentions:
350 Fields:
Translation:
AnimalsCells
-
Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. Blood. 2011 Mar 24; 117(12):3268-76.
Coghill JM, Sarantopoulos S, Moran TP, Murphy WJ, Blazar BR, Serody JS. PMID: 21245483; PMCID: PMC3069668.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
-
Americans hear as well or better today compared with 40 years ago: hearing threshold levels in the unscreened adult population of the United States, 1959-1962 and 1999-2004. Ear Hear. 2010 Dec; 31(6):725-34.
Hoffman HJ, Dobie RA, Ko CW, Themann CL, Murphy WJ. PMID: 20683190.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansPHPublic Health
-
Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy. J Exp Med. 2010 Oct 25; 207(11):2455-67.
Weiss JM, Ridnour LA, Back T, Hussain SP, He P, Maciag AE, Keefer LK, Murphy WJ, Harris CC, Wink DA, Wiltrout RH. PMID: 20921282; PMCID: PMC2964582.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Blood. 2010 Oct 07; 116(14):2484-93.
Zhou Q, Munger ME, Highfill SL, Tolar J, Weigel BJ, Riddle M, Sharpe AH, Vallera DA, Azuma M, Levine BL, June CH, Murphy WJ, Munn DH, Blazar BR. PMID: 20570856; PMCID: PMC2953885.
View in:
PubMed Mentions:
138 Fields:
Translation:
AnimalsCells
-
Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways. Curr Opin Pharmacol. 2010 Aug; 10(4):408-24.
Taub DD, Murphy WJ, Longo DL. PMID: 20595009; PMCID: PMC2914845.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
-
Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects. Immunotherapy. 2010 May; 2(3):399-418.
Bouchlaka MN, Redelman D, Murphy WJ. PMID: 20635904; PMCID: PMC3492055.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
The triterpenoid CDDO-Me delays murine acute graft-versus-host disease with the preservation of graft-versus-tumor effects after allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2010 Jun; 16(6):739-50.
Li M, Sun K, Redelman D, Welniak LA, Murphy WJ. PMID: 20338256; PMCID: PMC2866806.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Hematopoietic progenitor cell regulation by CD4+CD25+ T cells. Blood. 2010 Jun 10; 115(23):4934-43.
Urbieta M, Barao I, Jones M, Jurecic R, Panoskaltsis-Mortari A, Blazar BR, Murphy WJ, Levy RB. PMID: 20200356; PMCID: PMC2890189.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Activated allogeneic NK cells as suppressors of alloreactive responses. Biol Blood Marrow Transplant. 2010 Jun; 16(6):772-81.
Hu B, He Y, Wu Y, Bao G, Liu H, Welniak LA, Murphy WJ. PMID: 20197103.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection. Nat Immunol. 2010 Apr; 11(4):321-7.
Orr MT, Murphy WJ, Lanier LL. PMID: 20190757; PMCID: PMC2842453.
View in:
PubMed Mentions:
142 Fields:
Translation:
AnimalsCells
-
NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction. Biol Blood Marrow Transplant. 2010 May; 16(5):565-86.
Miller JS, Warren EH, van den Brink MR, Ritz J, Shlomchik WD, Murphy WJ, Barrett AJ, Kolb HJ, Giralt S, Bishop MR, Blazar BR, Falkenburg JH. PMID: 20152921; PMCID: PMC2858433.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCellsPHPublic Health
-
Supermatrix and species tree methods resolve phylogenetic relationships within the big cats, Panthera (Carnivora: Felidae). Mol Phylogenet Evol. 2010 Jul; 56(1):64-76.
Davis BW, Li G, Murphy WJ. PMID: 20138224.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Pattern and timing of diversification of the mammalian order Carnivora inferred from multiple nuclear gene sequences. Mol Phylogenet Evol. 2010 Jul; 56(1):49-63.
Eizirik E, Murphy WJ, Koepfli KP, Johnson WE, Dragoo JW, Wayne RK, O'Brien SJ. PMID: 20138220; PMCID: PMC7034395.
View in:
PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
-
Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation. . 2010 Jan 1; 199-219.
Goetz GD, Murphy MW. .
View in:
Publisher Site Mentions:
-
Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses. Adv Exp Med Biol. 2010; 684:155-65.
Alderson KL, Murphy WJ. PMID: 20795547.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Blood stem cell transplantation in older patients. Biol Blood Marrow Transplant. 2009 Dec; 15(12):1638-9.
Murphy WJ, Artz AS, Champlin RE, Koreth J, Longo DL, van den Brink MR. PMID: 19911448.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a review. Biol Blood Marrow Transplant. 2009 Dec; 15(12):1502-12.
Koreth J, Alyea EP, Murphy WJ, Welniak LA. PMID: 19896073; PMCID: PMC3501140.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Ecological adaptation determines functional mammalian olfactory subgenomes. Genome Res. 2010 Jan; 20(1):1-9.
Hayden S, Bekaert M, Crider TA, Mariani S, Murphy WJ, Teeling EC. PMID: 19952139; PMCID: PMC2798820.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansAnimals
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Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19455-60.
Weiss JM, Back TC, Scarzello AJ, Subleski JJ, Hall VL, Stauffer JK, Chen X, Micic D, Alderson K, Murphy WJ, Wiltrout RH. PMID: 19892741; PMCID: PMC2773732.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Molecular decay of the tooth gene Enamelin (ENAM) mirrors the loss of enamel in the fossil record of placental mammals. PLoS Genet. 2009 Sep; 5(9):e1000634.
Meredith RW, Gatesy J, Murphy WJ, Ryder OA, Springer MS. PMID: 19730686; PMCID: PMC2728479.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Utilization of Biocompatible Ferrous Particles for a New Cancer Therapy. . 2009 Jun 17; 565-566.
Evrensel EC, Welniak WL, Fuchs FA, Patel PJ, Murphy MW, Gordaninejad GF. .
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Publisher Site Mentions:
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Down modulation of IFN-gamma signaling in alveolar macrophages isolated from smokers. Toxicol Appl Pharmacol. 2009 May 15; 237(1):22-8.
Dhillon NK, Murphy WJ, Filla MB, Crespo AJ, Latham HA, O'Brien-Ladner A. PMID: 19269302; PMCID: PMC2680937.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition. Clin Exp Immunol. 2009 Mar; 155(3):504-13.
Ames E, Hallett WH, Murphy WJ. PMID: 19220837; PMCID: PMC2669527.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease. Am J Transplant. 2009 Mar; 9(3):452-62.
O'Shaughnessy MJ, Vogtenhuber C, Sun K, Sitcheran R, Baldwin AS, Murphy WJ, Dang L, Jaffee B, Palmer E, Serody JS, Blazar BR. PMID: 19260829; PMCID: PMC2680009.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus). Genome Res. 2009 Feb; 19(2):213-20.
Miller W, Drautz DI, Janecka JE, Lesk AM, Ratan A, Tomsho LP, Packard M, Zhang Y, McClellan LR, Qi J, Zhao F, Gilbert MT, Dalén L, Arsuaga JL, Ericson PG, Huson DH, Helgen KM, Murphy WJ, Götherström A, Schuster SC. PMID: 19139089; PMCID: PMC2652203.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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CD40 Stimulation and Antitumor Effects. . 2009 Jan 1; 227-239.
Wilkins WD, Murphy MW. .
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Publisher Site Mentions:
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Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses. Adv Exp Med Biol. 2009; 633:81-9.
Alderson KL, Murphy WJ. PMID: 19209683.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae. Genomics. 2009 Apr; 93(4):299-304.
Davis BW, Raudsepp T, Pearks Wilkerson AJ, Agarwala R, Schäffer AA, Houck M, Chowdhary BP, Murphy WJ. PMID: 18951970; PMCID: PMC2656592.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Raising the spectra of T-cell profiling. Blood. 2008 Oct 15; 112(8):3008-9.
Murphy WJ. PMID: 18840724; PMCID: PMC2569160.
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PubMed Mentions:
1 Fields:
-
Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses. Biol Blood Marrow Transplant. 2008 Oct; 14(10):1088-1099.
Hallett WHD, Ames E, Álvarez M, Barao I, Taylor PA, Blazar BR, Murphy WJ. PMID: 18804038; PMCID: PMC2735407.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease. Expert Opin Pharmacother. 2008 Sep; 9(13):2305-16.
Li M, Sun K, Welniak LA, Murphy WJ. PMID: 18710355; PMCID: PMC2658813.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Gene discovery and comparative analysis of X-degenerate genes from the domestic cat Y chromosome. Genomics. 2008 Nov; 92(5):329-38.
Pearks Wilkerson AJ, Raudsepp T, Graves T, Albracht D, Warren W, Chowdhary BP, Skow LC, Murphy WJ. PMID: 18674610.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection. Blood. 2008 Oct 15; 112(8):3508-16.
Taylor PA, Ehrhardt MJ, Lees CJ, Panoskaltsis-Mortari A, Krieg AM, Sharpe AH, Murphy WJ, Serody JS, Hemmi H, Akira S, Levy RB, Blazar BR. PMID: 18614760; PMCID: PMC2569186.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus. J Immunol. 2008 Jul 01; 181(1):47-61.
Puliaev R, Puliaeva I, Welniak LA, Ryan AE, Haas M, Murphy WJ, Via CS. PMID: 18566369; PMCID: PMC2613003.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation. Blood. 2008 Aug 15; 112(4):1522-9.
Sun K, Li M, Sayers TJ, Welniak LA, Murphy WJ. PMID: 18539902; PMCID: PMC2515132.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Morphology and placental mammal phylogeny. Syst Biol. 2008 Jun; 57(3):499-503.
Springer MS, Meredith RW, Eizirik E, Teeling E, Murphy WJ. PMID: 18570041.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody. J Natl Cancer Inst. 2008 May 07; 100(9):649-62.
Shanker A, Brooks AD, Tristan CA, Wine JW, Elliott PJ, Yagita H, Takeda K, Smyth MJ, Murphy WJ, Sayers TJ. PMID: 18445820; PMCID: PMC2753966.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network. Cell Immunol. 2008 Mar-Apr; 252(1-2):111-21.
Redelman D, Welniak LA, Taub D, Murphy WJ. PMID: 18313040; PMCID: PMC4777337.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy. J Immunol. 2008 Mar 01; 180(5):2981-8.
Alderson KL, Zhou Q, Berner V, Wilkins DE, Weiss JM, Blazar BR, Welniak LA, Wiltrout RH, Redelman D, Murphy WJ. PMID: 18292520; PMCID: PMC2408862.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor. BMC Evol Biol. 2008 Feb 20; 8:54.
Holmes RS, Chan J, Cox LA, Murphy WJ, VandeBerg JL. PMID: 18289373; PMCID: PMC2266714.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition. J Immunol. 2008 Jan 01; 180(1):163-70.
Hallett WH, Ames E, Motarjemi M, Barao I, Shanker A, Tamang DL, Sayers TJ, Hudig D, Murphy WJ. PMID: 18097016.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Construction of radiation hybrid panels. Methods Mol Biol. 2008; 422:51-64.
Page JE, Murphy WJ. PMID: 18629660.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Res. 2007 Dec; 17(12):1797-808.
Miller W, Rosenbloom K, Hardison RC, Hou M, Taylor J, Raney B, Burhans R, King DC, Baertsch R, Blankenberg D, Kosakovsky Pond SL, Nekrutenko A, Giardine B, Harris RS, Tyekucheva S, Diekhans M, Pringle TH, Murphy WJ, Lesk A, Weinstock GM, Lindblad-Toh K, Gibbs RA, Lander ES, Siepel A, Haussler D, Kent WJ. PMID: 17984227; PMCID: PMC2099589.
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PubMed Mentions:
167 Fields:
Translation:
HumansAnimalsCells
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Molecular and genomic data identify the closest living relative of primates. Science. 2007 Nov 02; 318(5851):792-4.
Janecka JE, Miller W, Pringle TH, Wiens F, Zitzmann A, Helgen KM, Springer MS, Murphy WJ. PMID: 17975064.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimals
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Initial sequence and comparative analysis of the cat genome. Genome Res. 2007 Nov; 17(11):1675-89.
Pontius JU, Mullikin JC, Smith DR, Agencourt Sequencing Team, Lindblad-Toh K, Gnerre S, Clamp M, Chang J, Stephens R, Neelam B, Volfovsky N, Schäffer AA, Agarwala R, Narfström K, Murphy WJ, Giger U, Roca AL, Antunes A, Menotti-Raymond M, Yuhki N, Pecon-Slattery J, Johnson WE, Bourque G, Tesler G, NISC Comparative Sequencing Program, O'Brien SJ. PMID: 17975172; PMCID: PMC2045150.
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PubMed Mentions:
171 Fields:
Translation:
HumansAnimalsCells
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The adequacy of morphology for reconstructing the early history of placental mammals. Syst Biol. 2007 Aug; 56(4):673-84.
Springer MS, Burk-Herrick A, Meredith R, Eizirik E, Teeling E, O'Brien SJ, Murphy WJ. PMID: 17661234.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Mammalian evolution and biomedicine: new views from phylogeny. Biol Rev Camb Philos Soc. 2007 Aug; 82(3):375-92.
Springer MS, Murphy WJ. PMID: 17624960.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Gene conversion between mammalian CCR2 and CCR5 chemokine receptor genes: a potential mechanism for receptor dimerization. Genomics. 2007 Aug; 90(2):213-24.
Vàzquez-Salat N, Yuhki N, Beck T, O'Brien SJ, Murphy WJ. PMID: 17544254.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells. J Immunol. 2007 May 01; 178(9):5753-61.
Zhou Q, Gault RA, Kozel TR, Murphy WJ. PMID: 17442959.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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A family matter: conclusive resolution of the taxonomic position of the long-fingered bats, miniopterus. Mol Biol Evol. 2007 Jul; 24(7):1553-61.
Miller-Butterworth CM, Murphy WJ, O'Brien SJ, Jacobs DS, Springer MS, Teeling EC. PMID: 17449895.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy. Nat Med. 2007 Mar; 13(3):354-60.
Berner V, Liu H, Zhou Q, Alderson KL, Sun K, Weiss JM, Back TC, Longo DL, Blazar BR, Wiltrout RH, Welniak LA, Redelman D, Murphy WJ. PMID: 17334371.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Use of systemic proteasome inhibition as an immune-modulating agent in disease. Endocr Metab Immune Disord Drug Targets. 2007 Mar; 7(1):29-34.
Mattingly LH, Gault RA, Murphy WJ. PMID: 17346202.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality. Biol Blood Marrow Transplant. 2007 May; 13(5):521-9.
Sun K, Li M, Konopleva M, Konoplev S, Stephens LC, Kornblau SM, Frolova O, Wilkins DE, Ma W, Welniak LA, Andreeff M, Murphy WJ. PMID: 17448911; PMCID: PMC4559277.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Using genomic data to unravel the root of the placental mammal phylogeny. Genome Res. 2007 Apr; 17(4):413-21.
Murphy WJ, Pringle TH, Crider TA, Springer MS, Miller W. PMID: 17322288; PMCID: PMC1832088.
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PubMed Mentions:
190 Fields:
Translation:
HumansAnimalsCells
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Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol. 2007; 25:139-70.
Welniak LA, Blazar BR, Murphy WJ. PMID: 17129175.
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PubMed Mentions:
219 Fields:
Translation:
HumansAnimals
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Designing and optimizing comparative anchor primers for comparative gene mapping and phylogenetic inference. Nat Protoc. 2007; 2(11):3022-30.
Murphy WJ, O'Brien SJ. PMID: 18007639.
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PubMed Mentions:
15 Fields:
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[Relationship between CCR5 and acute graft-versus-host disease in murine bone marrow transplantation]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2006 Oct; 14(5):934-40.
Wang Z, Murphy WJ. PMID: 17096892.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A 1.5-Mb-resolution radiation hybrid map of the cat genome and comparative analysis with the canine and human genomes. Genomics. 2007 Feb; 89(2):189-96.
Murphy WJ, Davis B, David VA, Agarwala R, Schäffer AA, Pearks Wilkerson AJ, Neelam B, O'Brien SJ, Menotti-Raymond M. PMID: 16997530; PMCID: PMC3760348.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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An approximately 140-kb deletion associated with feline spinal muscular atrophy implies an essential LIX1 function for motor neuron survival. Genome Res. 2006 Sep; 16(9):1084-90.
Fyfe JC, Menotti-Raymond M, David VA, Brichta L, Schäffer AA, Agarwala R, Murphy WJ, Wedemeyer WJ, Gregory BL, Buzzell BG, Drummond MC, Wirth B, O'Brien SJ. PMID: 16899656; PMCID: PMC1557767.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Positive and negative regulation of Natural Killer cells: therapeutic implications. Semin Cancer Biol. 2006 Oct; 16(5):367-82.
Hallett WH, Murphy WJ. PMID: 16934486.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression. J Immunol. 2006 Jun 01; 176(11):6543-52.
Shorts L, Weiss JM, Lee JK, Welniak LA, Subleski J, Back T, Murphy WJ, Wiltrout RH. PMID: 16709811.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis. Infect Immun. 2006 Apr; 74(4):2161-8.
Zhou Q, Gault RA, Kozel TR, Murphy WJ. PMID: 16552046; PMCID: PMC1418893.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Novel gene acquisition on carnivore Y chromosomes. PLoS Genet. 2006 Mar; 2(3):e43.
Murphy WJ, Pearks Wilkerson AJ, Raudsepp T, Agarwala R, Schäffer AA, Stanyon R, Chowdhary BP. PMID: 16596168; PMCID: PMC1420679.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells. Proc Natl Acad Sci U S A. 2006 Apr 04; 103(14):5460-5.
Barao I, Hanash AM, Hallett W, Welniak LA, Sun K, Redelman D, Blazar BR, Levy RB, Murphy WJ. PMID: 16567639; PMCID: PMC1459377.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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The late Miocene radiation of modern Felidae: a genetic assessment. Science. 2006 Jan 06; 311(5757):73-7.
Johnson WE, Eizirik E, Pecon-Slattery J, Murphy WJ, Antunes A, Teeling E, O'Brien SJ. PMID: 16400146.
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PubMed Mentions:
179 Fields:
Translation:
AnimalsCells
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Immune response and immunotherapy to Cryptococcus infections. Immunol Res. 2006; 35(3):191-208.
Zhou Q, Murphy WJ. PMID: 17172646.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis. Ann N Y Acad Sci. 2005 Nov; 1059:160-7.
Brooks AD, Ramirez T, Toh U, Onksen J, Elliott PJ, Murphy WJ, Sayers TJ. PMID: 16382051.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol Immunother. 2006 Jan; 55(1):76-84.
Sayers TJ, Murphy WJ. PMID: 15864587; PMCID: PMC11030731.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L. Cell Immunol. 2005 Jun; 235(2):145-52.
Lee JK, Seki N, Sayers TJ, Subleski J, Gruys EM, Murphy WJ, Wiltrout RH. PMID: 16213477.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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A rhesus macaque radiation hybrid map and comparative analysis with the human genome. Genomics. 2005 Oct; 86(4):383-95.
Murphy WJ, Agarwala R, Schäffer AA, Stephens R, Smith C, Crumpler NJ, David VA, O'Brien SJ. PMID: 16039092.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD). Philos Trans R Soc Lond B Biol Sci. 2005 Sep 29; 360(1461):1747-67.
Blazar BR, Murphy WJ. PMID: 16147539; PMCID: PMC1569546.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation. Blood. 2006 Jan 01; 107(1):410-2.
Welniak LA, Kuprash DV, Tumanov AV, Panoskaltsis-Mortari A, Blazar BR, Sun K, Nedospasov SA, Murphy WJ. PMID: 16160014; PMCID: PMC1895345.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science. 2005 Jul 22; 309(5734):613-7.
Murphy WJ, Larkin DM, Everts-van der Wind A, Bourque G, Tesler G, Auvil L, Beever JE, Chowdhary BP, Galibert F, Gatzke L, Hitte C, Meyers SN, Milan D, Ostrander EA, Pape G, Parker HG, Raudsepp T, Rogatcheva MB, Schook LB, Skow LC, Welge M, Womack JE, O'brien SJ, Pevzner PA, Lewin HA. PMID: 16040707.
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PubMed Mentions:
240 Fields:
Translation:
HumansAnimalsCells
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In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells. J Immunol. 2005 Jul 15; 175(2):693-9.
Ortaldo JR, Winkler-Pickett RT, Bere EW, Watanabe M, Murphy WJ, Wiltrout RH. PMID: 16002664.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood. 2005 Nov 01; 106(9):3293-9.
Sun K, Wilkins DE, Anver MR, Sayers TJ, Panoskaltsis-Mortari A, Blazar BR, Welniak LA, Murphy WJ. PMID: 15961519; PMCID: PMC1895334.
View in:
PubMed Mentions:
52 Fields:
Translation:
Animals
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Novel tumor necrosis factor-knockout mice that lack Peyer's patches. Eur J Immunol. 2005 May; 35(5):1592-600.
Kuprash DV, Tumanov AV, Liepinsh DJ, Koroleva EP, Drutskaya MS, Kruglov AA, Shakhov AN, Southon E, Murphy WJ, Tessarollo L, Grivennikov SI, Nedospasov SA. PMID: 15832287.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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Insertional polymorphisms of endogenous feline leukemia viruses. J Virol. 2005 Apr; 79(7):3979-86.
Roca AL, Nash WG, Menninger JC, Murphy WJ, O'Brien SJ. PMID: 15767400; PMCID: PMC1061563.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Lack of correlation between an assay used to determine early marrow allograft rejection and long-term chimerism after murine allogeneic bone marrow transplantation: effects of marrow dose. Biol Blood Marrow Transplant. 2005 Apr; 11(4):252-9.
Koh CY, Welniak LA, Murphy WJ. PMID: 15812390.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Serum-dependent potentiation of lipopolysaccharide-induced nitric oxide production is mediated by the events after the transcription of inducible type of nitric oxide synthase. Cell Immunol. 2005 Mar; 234(1):16-22.
Zhang YH, Murphy WJ, Russell SW, Morrison DC, Koide N, Yoshida T, Yokochi T. PMID: 15936007.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A molecular phylogeny for bats illuminates biogeography and the fossil record. Science. 2005 Jan 28; 307(5709):580-4.
Teeling EC, Springer MS, Madsen O, Bates P, O'brien SJ, Murphy WJ. PMID: 15681385.
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PubMed Mentions:
365 Fields:
Translation:
Animals
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The feline major histocompatibility complex is rearranged by an inversion with a breakpoint in the distal class I region. Immunogenetics. 2005 Jan; 56(10):702-9.
Beck TW, Menninger J, Murphy WJ, Nash WG, O'brien SJ, Yuhki N. PMID: 15592824.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Mammalian phylogenomics comes of age. Trends Genet. 2004 Dec; 20(12):631-9.
Murphy WJ, Pevzner PA, O'Brien SJ. PMID: 15522459.
View in:
PubMed Mentions:
136 Fields:
Translation:
HumansAnimals
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Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration. Blood. 2005 Jan 01; 105(1):428-31.
Gendelman M, Halligan N, Komorowski R, Logan B, Murphy WJ, Blazar BR, Pritchard KA, Drobyski WR. PMID: 15331451.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
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Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects. Biol Blood Marrow Transplant. 2004 Aug; 10(8):534-9.
Welniak LA, Shorts L, Subleski J, Blazar BR, Wiltrout RH, Murphy WJ. PMID: 15282531.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Mesozoic origin for West Indian insectivores. Nature. 2004 Jun 10; 429(6992):649-51.
Roca AL, Bar-Gal GK, Eizirik E, Helgen KM, Maria R, Springer MS, O'Brien SJ, Murphy WJ. PMID: 15190349.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib. Proc Natl Acad Sci U S A. 2004 May 25; 101(21):8120-5.
Sun K, Welniak LA, Panoskaltsis-Mortari A, O'Shaughnessy MJ, Liu H, Barao I, Riordan W, Sitcheran R, Wysocki C, Serody JS, Blazar BR, Sayers TJ, Murphy WJ. PMID: 15148407; PMCID: PMC419567.
View in:
PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
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mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):5042-7.
Kozel TR, Murphy WJ, Brandt S, Blazar BR, Lovchik JA, Thorkildson P, Percival A, Lyons CR. PMID: 15051894; PMCID: PMC387370.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease. Exp Hematol. 2004 Mar; 32(3):318-24.
Welniak LA, Wang Z, Sun K, Kuziel W, Anver MR, Blazar BR, Murphy WJ. PMID: 15003318.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Natural killer cells: biology and clinical use in cancer therapy. Cell Mol Immunol. 2004 Feb; 1(1):12-21.
Hallett WH, Murphy WJ. PMID: 16212916.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides. J Immunol. 2004 Jan 15; 172(2):943-53.
Ortaldo JR, Young HA, Winkler-Pickett RT, Bere EW, Murphy WJ, Wiltrout RH. PMID: 14707067.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis. Biol Blood Marrow Transplant. 2004 Jan; 10(1):32-9.
Welniak LA, Karas M, Yakar S, Anver MR, Murphy WJ, LeRoith D. PMID: 14752777.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
The immunobiology of natural killer cells and bone marrow allograft rejection. Biol Blood Marrow Transplant. 2003 Dec; 9(12):727-41.
Barao I, Murphy WJ. PMID: 14677112.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration. Clin Immunol. 2003 Nov; 109(2):197-202.
Dorshkind K, Welniak L, Gault RA, Hixon J, Montecino-Rodriguez E, Horseman ND, Gertner JM, Murphy WJ. PMID: 14597218.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Reconstructing the genomic architecture of mammalian ancestors using multispecies comparative maps. Hum Genomics. 2003 Nov; 1(1):30-40.
Murphy WJ, Bourque G, Tesler G, Pevzner P, O'Brien SJ. PMID: 15601531; PMCID: PMC3525001.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Genomics. A dog's breakfast? Science. 2003 Sep 26; 301(5641):1854-5.
O'Brien SJ, Murphy WJ. PMID: 14512608.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Nuclear gene sequences confirm an ancient link between New Zealand's short-tailed bat and South American noctilionoid bats. Mol Phylogenet Evol. 2003 Aug; 28(2):308-19.
Teeling EC, Madsen O, Murphy WJ, Springer MS, O'Brien SJ. PMID: 12878467.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade. Blood. 2003 Dec 01; 102(12):4067-75.
Koh CY, Ortaldo JR, Blazar BR, Bennett M, Murphy WJ. PMID: 12893752.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
The origin of human chromosome 1 and its homologs in placental mammals. Genome Res. 2003 Aug; 13(8):1880-8.
Murphy WJ, Frönicke L, O'Brien SJ, Stanyon R. PMID: 12869576; PMCID: PMC403779.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice. Biol Blood Marrow Transplant. 2003 Jul; 9(7):426-34.
Sun R, Gault RA, Welniak LA, Tian ZG, Richards S, Murphy WJ. PMID: 12869956.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood. 2003 Sep 15; 102(6):1966-77.
Salcedo R, Zhang X, Young HA, Michael N, Wasserman K, Ma WH, Martins-Green M, Murphy WJ, Oppenheim JJ. PMID: 12791666.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
-
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood. 2003 Jul 01; 102(1):303-10.
Sayers TJ, Brooks AD, Koh CY, Ma W, Seki N, Raziuddin A, Blazar BR, Zhang X, Elliott PJ, Murphy WJ. PMID: 12637321.
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PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
-
Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses. J Immunol. 2003 Mar 01; 170(5):2727-33.
Murphy WJ, Welniak L, Back T, Hixon J, Subleski J, Seki N, Wigginton JM, Wilson SE, Blazar BR, Malyguine AM, Sayers TJ, Wiltrout RH. PMID: 12594303.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function. Blood. 2003 Jun 15; 101(12):5076-83.
Chen ZM, O'Shaughnessy MJ, Gramaglia I, Panoskaltsis-Mortari A, Murphy WJ, Narula S, Roncarolo MG, Blazar BR. PMID: 12609834.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Placental mammal diversification and the Cretaceous-Tertiary boundary. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):1056-61.
Springer MS, Murphy WJ, Eizirik E, O'Brien SJ. PMID: 12552136; PMCID: PMC298725.
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PubMed Mentions:
251 Fields:
Translation:
AnimalsCells
-
Chapter 5 Growth hormone. . 2003 Jan 1; I(Cell741993):103-113.
Welniak WL, Murphy MW. .
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Publisher Site Mentions:
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UVB light suppresses nitric oxide production by murine keratinocytes and macrophages. Biochem Pharmacol. 2002 Nov 15; 64(10):1469-81.
Sur R, Heck DE, Mariano TM, Jin Y, Murphy WJ, Laskin JD. PMID: 12417260.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens. Blood. 2002 Oct 15; 100(8):3026-33.
Raziuddin A, Longo DL, Bennett M, Winkler-Pickett R, Ortaldo JR, Murphy WJ. PMID: 12351417.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma xenografts. Clin Cancer Res. 2002 Aug; 8(8):2655-65.
Salcedo R, Martins-Green M, Gertz B, Oppenheim JJ, Murphy WJ. PMID: 12171898.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax. Blood. 2002 Jul 01; 100(1):217-23.
Szocinski JL, Khaled AR, Hixon J, Halverson D, Funakoshi S, Fanslow WC, Boyd A, Taub DD, Durum SK, Siegall CB, Longo DL, Murphy WJ. PMID: 12070030.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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The Feline Genome Project. Annu Rev Genet. 2002; 36:657-86.
O'Brien SJ, Menotti-Raymond M, Murphy WJ, Yuhki N. PMID: 12359739.
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PubMed Mentions:
24 Fields:
Translation:
Animals
-
Susceptibility to the ototoxic properties of toluene is species specific. Hear Res. 2002 Apr; 166(1-2):24-32.
Davis RR, Murphy WJ, Snawder JE, Striley CA, Henderson D, Khan A, Krieg EF. PMID: 12062755.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Low responsiveness to IFN-gamma, after pretreatment of mouse macrophages with lipopolysaccharides, develops via diverse regulatory pathways. Eur J Immunol. 2002 03; 32(3):710-9.
Crespo A, Filla MB, Murphy WJ. PMID: 11870615.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
The role of growth hormone in T-cell development and reconstitution. J Leukoc Biol. 2002 Mar; 71(3):381-7.
Welniak LA, Sun R, Murphy WJ. PMID: 11867675.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut. Biol Blood Marrow Transplant. 2002; 8(6):316-25.
Hixon JA, Anver MR, Blazar BR, Panoskaltsis-Mortari A, Wiltrout RH, Murphy WJ. PMID: 12108917.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells. J Immunol. 2002 Jan 01; 168(1):434-42.
Cui YH, Le Y, Gong W, Proost P, Van Damme J, Murphy WJ, Wang JM. PMID: 11751990.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
Potential applications of growth hormone in promoting immune reconstitution. . 2002 Jan 1; 2:101-110.
Welniak WL, Sun SR, Murphy MW. .
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Publisher Site Mentions:
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NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution. Biol Blood Marrow Transplant. 2002; 8(1):17-25.
Koh CY, Raziuddin A, Welniak LA, Blazar BR, Bennett M, Murphy WJ. PMID: 11846352.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer. Stem Cells. 2002; 20(6):573-82.
Kadereit S, Deeds LS, Haynesworth SE, Koc ON, Kozik MM, Szekely E, Daum-Woods K, Goetchius GW, Fu P, Welniak LA, Murphy WJ, Laughlin MJ. PMID: 12456965.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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The diverse role of chemokines in tumor progression: prospects for intervention (Review). Int J Mol Med. 2001 Sep; 8(3):235-44.
Schneider GP, Salcedo R, Welniak LA, Howard OM, Murphy WJ. PMID: 11494048.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells. J Immunol. 2001 Jun 15; 166(12):7571-8.
Salcedo R, Young HA, Ponce ML, Ward JM, Kleinman HK, Murphy WJ, Oppenheim JJ. PMID: 11390513.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies. Immunol Rev. 2001 Jun; 181:279-89.
Murphy WJ, Koh CY, Raziuddin A, Bennett M, Longo DL. PMID: 11513149.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo. Blood. 2001 May 15; 97(10):3132-7.
Koh CY, Blazar BR, George T, Welniak LA, Capitini CM, Raziuddin A, Murphy WJ, Bennett M. PMID: 11342440.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
-
The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice. Biochem Biophys Res Commun. 2001 Apr 13; 282(4):971-6.
Tani K, Murphy WJ, Chertov O, Oppenheim JJ, Wang JM. PMID: 11352647.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation. J Immunol. 2001 Mar 01; 166(5):2924-8.
Welniak LA, Khaled AR, Anver MR, Komschlies KL, Wiltrout RH, Durum S, Ruscetti FR, Blazar BR, Murphy WJ. PMID: 11207240.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Thymic emigrants isolated by a new method possess unique phenotypic and functional properties. Blood. 2001 Mar 01; 97(5):1360-9.
Lee CK, Kim K, Welniak LA, Murphy WJ, Muegge K, Durum SK. PMID: 11222381.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Role of interleukin-12 in acute graft-versus-host disease(1). Transplant Proc. 2001 Feb-Mar; 33(1-2):1752-3.
Welniak LA, Blazar BR, Wiltrout RH, Anver MR, Murphy WJ. PMID: 11267498.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease. Blood. 2001 Jan 15; 97(2):565-71.
Boussiotis VA, Chen ZM, Zeller JC, Murphy WJ, Berezovskaya A, Narula S, Roncarolo MG, Blazar BR. PMID: 11154238.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2001; 7(3):136-43.
Hixon JA, Blazar BR, Anver MR, Wiltrout RH, Murphy WJ. PMID: 11302547.
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PubMed Mentions:
15 Fields:
Translation:
Animals
-
Alternative strategies other than growth hormone for the treatment of immune diseases. Trends Immunol. 2001 Jan; 22(1):14-6.
Famularo G, Di Marzio L, Ulisse S, Cifone MG, De Simone C. PMID: 11334029.
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PubMed Mentions: Fields:
Translation:
Humans
-
Effects of prolactin on hematopoiesis. Lupus. 2001; 10(10):700-5.
Welniak LA, Richards SM, Murphy WJ. PMID: 11721696.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury. Blood. 2000 Dec 15; 96(13):4350-6.
Panoskaltsis-Mortari A, Taylor PA, Rubin JS, Uren A, Welniak LA, Murphy WJ, Farrell CL, Lacey DL, Blazar BR. PMID: 11110712.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCellsPHPublic Health
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Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions. J Immunol. 2000 Nov 01; 165(9):4901-9.
Blazar BR, Lees CJ, Martin PJ, Noelle RJ, Kwon B, Murphy W, Taylor PA. PMID: 11046015.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Adoptive cellular immunotherapy: NK cells and bone marrow transplantation. Histol Histopathol. 2000 10; 15(4):1201-10.
Koh CY, Welniak LA, Murphy WJ. PMID: 11005245.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Use of human prolactin as a therapeutic protein to potentiate immunohematopoietic function. J Neuroimmunol. 2000 Sep 01; 109(1):56-62.
Richards SM, Murphy WJ. PMID: 10969182.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes. J Clin Invest. 2000 Sep; 106(6):745-7.
Murphy WJ. PMID: 10995784; PMCID: PMC381400.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation. Blood. 2000 Aug 01; 96(3):834-9.
Panoskaltsis-Mortari A, Strieter RM, Hermanson JR, Fegeding KV, Murphy WJ, Farrell CL, Lacey DL, Blazar BR. PMID: 10910893.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Effects of growth hormone and prolactin on hematopoiesis. Leuk Lymphoma. 2000 Aug; 38(5-6):435-45.
Welniak LA, Tian ZG, Sun R, Keller JR, Richards S, Ruscetti FW, Murphy WJ. PMID: 10953965.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood. 2000 Jul 01; 96(1):34-40.
Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK, Oppenheim JJ, Murphy WJ. PMID: 10891427.
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PubMed Mentions:
297 Fields:
Translation:
HumansAnimalsCells
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Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts. Blood. 2000 Jun 15; 95(12):3840-4.
Raziuddin A, Bennett M, Winkler-Pickett R, Ortaldo JR, Longo DL, Murphy WJ. PMID: 10845918.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Role for CD40-CD40 ligand interactions in the immune response to solid tumours. Mol Immunol. 2000 Jun; 37(9):515-26.
Alexandroff AB, Jackson AM, Paterson T, Haley JL, Ross JA, Longo DL, Murphy WJ, James K, Taub DD. PMID: 11163401.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens. Int Immunol. 2000 May; 12(5):691-700.
Tani K, Murphy WJ, Chertov O, Salcedo R, Koh CY, Utsunomiya I, Funakoshi S, Asai O, Herrmann SH, Wang JM, Kwak LW, Oppenheim JJ. PMID: 10784615.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Growth hormone as an immunomodulating therapeutic agent. Immunol Today. 2000 May; 21(5):211-3.
Murphy WJ, Longo DL. PMID: 10877541.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Inhibition of MDA-MB-231 human breast tumor xenografts and HER2 expression by anti-tumor agents GAP31 and MAP30. Anticancer Res. 2000 Mar-Apr; 20(2A):653-9.
Lee-Huang S, Huang PL, Sun Y, Chen HC, Kung HF, Huang PL, Murphy WJ. PMID: 10810336.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning. Biol Blood Marrow Transplant. 2000; 6(6):604-12.
Welniak LA, Blazar BR, Anver MR, Wiltrout RH, Murphy WJ. PMID: 11128810.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Differential effects of CD40 stimulation on normal and neoplastic cell growth. Arch Immunol Ther Exp (Warsz). 2000; 48(4):225-33.
Ziebold JL, Hixon J, Boyd A, Murphy WJ. PMID: 11059638.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
New strategies for preventing graft-versus-host disease. Curr Opin Immunol. 1999 Oct; 11(5):509-15.
Murphy WJ, Blazar BR. PMID: 10508701.
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PubMed Mentions:
9 Fields:
Translation:
Cells
-
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta. J Immunol. 1999 Oct 01; 163(7):3684-91.
Zeller JC, Panoskaltsis-Mortari A, Murphy WJ, Ruscetti FW, Narula S, Roncarolo MG, Blazar BR. PMID: 10490963.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Ly-49 receptor expression and functional analysis in multiple mouse strains. J Leukoc Biol. 1999 Sep; 66(3):512-20.
Ortaldo JR, Mason AT, Winkler-Pickett R, Raziuddin A, Murphy WJ, Mason LH. PMID: 10496323.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells. J Leukoc Biol. 1999 Jun; 65(6):891-9.
Kirken RA, Erwin RA, Taub D, Murphy WJ, Behbod F, Wang L, Pericle F, Farrar WL. PMID: 10380915.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
-
Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand. Blood. 1999 May 01; 93(9):2999-3007.
Hirano A, Longo DL, Taub DD, Ferris DK, Young LS, Eliopoulos AG, Agathanggelou A, Cullen N, Macartney J, Fanslow WC, Murphy WJ. PMID: 10216096.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine. Exp Hematol. 1999 May; 27(5):811-6.
Woody MA, Welniak LA, Sun R, Tian ZG, Henry M, Richards S, Raziuddin A, Longo DL, Murphy WJ. PMID: 10340396.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha. Am J Pathol. 1999 Apr; 154(4):1125-35.
Salcedo R, Wasserman K, Young HA, Grimm MC, Howard OM, Anver MR, Kleinman HK, Murphy WJ, Oppenheim JJ. PMID: 10233851; PMCID: PMC1866563.
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PubMed Mentions:
149 Fields:
Translation:
HumansAnimalsCells
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Cloning thymic precursor cells: demonstration that individual pro-T1 cells have dual T-NK potential and individual pro-T2 cells have dual alphabeta-gammadelta T cell potential. Cell Immunol. 1999 Feb 01; 191(2):139-44.
Lee CK, Kim K, Geiman TM, Murphy WJ, Muegge K, Durum SK. PMID: 9973536.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Generation of artificial proteoglycans containing glycosaminoglycan-modified CD44. Demonstration of the interaction between rantes and chondroitin sulfate. J Biol Chem. 1999 Jan 22; 274(4):2518-24.
Wolff EA, Greenfield B, Taub DD, Murphy WJ, Bennett KL, Aruffo A. PMID: 9891023.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Use of neuroendocrine hormones to promote reconstitution after bone marrow transplantation. Neuroimmunomodulation. 1999 Jan-Apr; 6(1-2):69-80.
Woody MA, Welniak LA, Richards S, Taub DD, Tian Z, Sun R, Longo DL, Murphy WJ. PMID: 9876237.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
CD40 stimulation promotes human secondary immunoglobulin responses in HuPBL-SCID chimeras. Clin Immunol. 1999 Jan; 90(1):22-7.
Murphy WJ, Funakoshi S, Fanslow WC, Rager HC, Taub DD, Longo DL. PMID: 9884349.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest. 1998 Nov 01; 102(9):1742-8.
Murphy WJ, Welniak LA, Taub DD, Wiltrout RH, Taylor PA, Vallera DA, Kopf M, Young H, Longo DL, Blazar BR. PMID: 9802888; PMCID: PMC509122.
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PubMed Mentions:
75 Fields:
Translation:
Animals
-
CD16 cross-linking blocks rearrangement of the TCR beta locus and development of alpha beta T cells and induces development of NK cells from thymic progenitors. J Immunol. 1998 Oct 01; 161(7):3325-9.
Durum SK, Lee CK, Geiman TM, Murphy WJ, Muegge K. PMID: 9759848.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice. Exp Hematol. 1998 Jun; 26(6):507-14.
Spence SE, Keller JR, Ruscetti FW, McCauslin CS, Gooya JM, Funakoshi S, Longo DL, Murphy WJ. PMID: 9620284.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients. AIDS. 1998 May 28; 12(8):895-904.
Nguyen BY, Clerici M, Venzon DJ, Bauza S, Murphy WJ, Longo DL, Baseler M, Gesundheit N, Broder S, Shearer G, Yarchoan R. PMID: 9631143.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
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In vivo alloreactive potential of ex vivo-expanded primary T lymphocytes. Transplantation. 1998 May 27; 65(10):1365-70.
Contassot E, Murphy W, Angonin R, Pavy JJ, Bittencourt MC, Robinet E, Reynolds CW, Cahn JY, Hervé P, Tiberghien P. PMID: 9625020.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation. J Clin Invest. 1998 May 01; 101(9):1835-42.
Asai O, Longo DL, Tian ZG, Hornung RL, Taub DD, Ruscetti FW, Murphy WJ. PMID: 9576746; PMCID: PMC508768.
View in:
PubMed Mentions:
88 Fields:
Translation:
AnimalsCells
-
Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice. Stem Cells. 1998; 16(3):193-9.
Tian ZG, Woody MA, Sun R, Welniak LA, Raziuddin A, Funakoshi S, Tsarfaty G, Longo DL, Murphy WJ. PMID: 9617894.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets. J Immunol. 1998 Jan 01; 160(1):87-94.
Raziuddin A, Longo DL, Mason L, Ortaldo JR, Bennett M, Murphy WJ. PMID: 9551959.
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10 Fields:
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AnimalsCells
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Prospects for cytokine and chemokine biotherapy. Clin Cancer Res. 1997 Dec; 3(12 Pt 2):2682-6.
Oppenheim JJ, Murphy WJ, Chertox O, Schirrmacher V, Wang JM. PMID: 10068274.
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13 Fields:
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HumansAnimalsCells
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Antitumor effects of nonconjugated murine Lym-2 and human-mouse chimeric CLL-1 monoclonal antibodies against various human lymphoma cell lines in vitro and in vivo. Blood. 1997 Oct 15; 90(8):3160-6.
Funakoshi S, Hirano A, Beckwith M, Asai O, Jorgensen G, Tian Z, Hornick JL, Hu P, Khawli LA, Epstein AL, Longo DL, Murphy WJ. PMID: 9376598.
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HumansAnimalsCells
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Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils. J Exp Med. 1997 Aug 29; 186(5):739-47.
Chertov O, Ueda H, Xu LL, Tani K, Murphy WJ, Wang JM, Howard OM, Sayers TJ, Oppenheim JJ. PMID: 9271589; PMCID: PMC2199011.
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81 Fields:
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HumansAnimalsCells
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The potential role of NK cells in the separation of graft-versus-tumor effects from graft-versus-host disease after allogeneic bone marrow transplantation. Immunol Rev. 1997 Jun; 157:167-76.
Murphy WJ, Longo DL. PMID: 9255629.
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4 Fields:
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HumansAnimalsCells
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Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin. J Immunol. 1997 Mar 15; 158(6):2745-55.
Taub DD, Murphy WJ, Asai O, Fenton RG, Peltz G, Key ML, Turcovski-Corrales S, Longo DL. PMID: 9058809.
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6 Fields:
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HumansCells
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Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice. J Clin Invest. 1997 Feb 01; 99(3):484-91.
Funakoshi S, Taub DD, Anver MR, Raziuddin A, Asai O, Reddy V, Rager H, Fanslow WC, Longo DL, Murphy WJ. PMID: 9022082; PMCID: PMC507822.
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5 Fields:
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AnimalsCells
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Effects of CD40 stimulation in the prevention of human EBV-lymphomagenesis. Leuk Lymphoma. 1997 Jan; 24(3-4):187-99.
Funakoshi S, Taub DD, Asai O, Hirano A, Ruscetti FW, Longo DL, Murphy WJ. PMID: 9156649.
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3 Fields:
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HumansAnimalsCells
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Chemokine-induced human lymphocyte infiltration and engraftment in huPBL-SCID mice. Methods Enzymol. 1997; 287:265-91.
Taub DD, Key ML, Longo DL, Murphy WJ. PMID: 9330328.
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2 Fields:
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HumansAnimalsCells
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Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice. Int Immunol. 1996 Dec; 8(12):1833-9.
Raziuddin A, Longo DL, Mason L, Ortaldo JR, Murphy WJ. PMID: 8982767.
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4 Fields:
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AnimalsCells
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Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T-cell infiltration into human melanoma xenografts. J Immunother Emphasis Tumor Immunol. 1996 Sep; 19(5):317-23.
Conlon KC, Anver MR, Longo DL, Ortaldo JR, Murphy WJ. PMID: 8941871.
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1 Fields:
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HumansAnimalsCells
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IL-8-Induced T-Lymphocyte Migration: Direct as Well as Indirect Mechanisms Methods. 1996 Aug; 10(1):135-44.
Wang JM, Xu L, Murphy WJ, Taub DD, Chertov O. PMID: 8812653.
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6 Fields:
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The huPBL-SCID mouse as a means to examine human immune function in vivo. Semin Immunol. 1996 Aug; 8(4):233-41.
Murphy WJ, Taub DD, Longo DL. PMID: 8883146.
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13 Fields:
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HumansAnimalsCells
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T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest. 1996 Apr 15; 97(8):1931-41.
Taub DD, Anver M, Oppenheim JJ, Longo DL, Murphy WJ. PMID: 8621778; PMCID: PMC507263.
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78 Fields:
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HumansAnimalsCells
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Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection. Blood. 1996 Apr 01; 87(7):2723-31.
Schwarzenberger P, Spence S, Lohrey N, Kmiecik T, Longo DL, Murphy WJ, Ruscetti FW, Keller JR. PMID: 8639888.
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2 Fields:
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HumansAnimalsCells
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NK Cells in the Regulation of Hematopoiesis Methods. 1996 Apr; 9(2):344-51.
Murphy WJ, Longo DL. PMID: 8812687.
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3 Fields:
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Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice. J Immunol. 1996 Mar 15; 156(6):2104-11.
Murphy WJ, Tian ZG, Asai O, Funakoshi S, Rotter P, Henry M, Strieter RM, Kunkel SL, Longo DL, Taub DD. PMID: 8690898.
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12 Fields:
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HumansAnimalsCells
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Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro. J Immunol. 1996 Mar 15; 156(6):2095-2103.
Taub DD, Turcovski-Corrales SM, Key ML, Longo DL, Murphy WJ. PMID: 8690897.
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84 Fields:
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HumansCells
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Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas. J Immunother Emphasis Tumor Immunol. 1996 Mar; 19(2):93-101.
Funakoshi S, Longo DL, Murphy WJ. PMID: 8732692.
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6 Fields:
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HumansAnimalsCells
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Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice. Blood. 1996 Feb 15; 87(4):1423-31.
Taub DD, Longo DL, Murphy WJ. PMID: 8608232.
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38 Fields:
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HumansAnimalsCells
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Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem. 1996 Feb 09; 271(6):2935-40.
Chertov O, Michiel DF, Xu L, Wang JM, Tani K, Murphy WJ, Longo DL, Taub DD, Oppenheim JJ. PMID: 8621683.
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149 Fields:
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HumansAnimalsCells
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Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production. J Leukoc Biol. 1996 Jan; 59(1):81-9.
Taub DD, Ortaldo JR, Turcovski-Corrales SM, Key ML, Longo DL, Murphy WJ. PMID: 8558072.
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44 Fields:
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HumansAnimalsCells
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In vivo antitumor effects of unconjugated CD30 monoclonal antibodies on human anaplastic large-cell lymphoma xenografts. Cancer Res. 1995 Nov 15; 55(22):5335-41.
Tian ZG, Longo DL, Funakoshi S, Asai O, Ferris DK, Widmer M, Murphy WJ. PMID: 7585597.
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16 Fields:
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HumansAnimalsCells
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Engraftment of SCID mice by human bone marrow hematopoietic cells cultured in vitro: an in vivo model for human gene transfer. Leukemia. 1995 Oct; 9 Suppl 1:S43-7.
Spence SE, Keller JR, Ruscetti FW, Czarra KT, Gooya JM, Funakoshi S, Longo DL, Murphy WJ. PMID: 7475312.
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HumansAnimalsCells
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NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice. J Immunol. 1995 Sep 15; 155(6):2911-7.
Murphy WJ, Raziuddin A, Mason L, Kumar V, Bennett M, Longo DL. PMID: 7673708.
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3 Fields:
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AnimalsCells
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Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocytes. Blood. 1995 Sep 01; 86(5):1946-53.
Murphy WJ, Funakoshi S, Beckwith M, Rushing SE, Conley DK, Armitage RJ, Fanslow WC, Rager HC, Taub DD, Ruscetti FW, et al. PMID: 7544649.
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3 Fields:
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HumansAnimalsCells
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A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion. J Immunol. 1995 Aug 01; 155(3):1184-90.
Xu L, Badolato R, Murphy WJ, Longo DL, Anver M, Hale S, Oppenheim JJ, Wang JM. PMID: 7636186.
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50 Fields:
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HumansAnimalsCells
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Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta. Cell Growth Differ. 1995 Jun; 6(6):655-63.
Turley JM, Funakoshi S, Ruscetti FW, Kasper J, Murphy WJ, Longo DL, Birchenall-Roberts MC. PMID: 7669719.
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9 Fields:
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HumansCells
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Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes. J Clin Invest. 1995 Mar; 95(3):1370-6.
Taub DD, Proost P, Murphy WJ, Anver M, Longo DL, van Damme J, Oppenheim JJ. PMID: 7883984; PMCID: PMC441477.
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79 Fields:
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HumansAnimalsCells
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Cellular and molecular studies in the treatment of murine renal cancer. Semin Oncol. 1995 Feb; 22(1):9-16.
Wiltrout RH, Gregorio TA, Fenton RG, Longo DL, Ghosh P, Murphy WJ, Komschlies KL. PMID: 7855624.
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3 Fields:
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HumansAnimals
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Epstein-Barr virus-induced human B-cell lymphoma arising in HuPBL-SCID chimeric mice: characterization and the role of CD40 stimulation in their treatment and prevention. Pathobiology. 1995; 63(3):133-42.
Funakoshi S, Beckwith M, Fanslow W, Longo DL, Murphy WJ. PMID: 8821629.
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2 Fields:
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HumansAnimalsCells
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Effects of growth hormone and prolactin immune development and function. Life Sci. 1995; 57(1):1-14.
Murphy WJ, Rui H, Longo DL. PMID: 7596216.
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13 Fields:
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HumansAnimals
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Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration. Exp Hematol. 1994 Dec; 22(13):1273-7.
Tsarfaty G, Longo DL, Murphy WJ. PMID: 7957713.
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8 Fields:
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AnimalsCells
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Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation? Blood. 1994 Aug 15; 84(4):1333-41.
Tiberghien P, Reynolds CW, Keller J, Spence S, Deschaseaux M, Certoux JM, Contassot E, Murphy WJ, Lyons R, Chiang Y, et al. PMID: 8049449.
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18 Fields:
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HumansCells
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Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID). J Immunol. 1994 Aug 01; 153(3):1004-14.
Murphy WJ, Durum SK, Anver MR, Ferris DK, McVicar DW, O'Shea JJ, Ruscetti SK, Smith MR, Young HA, Longo DL. PMID: 7913108.
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10 Fields:
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AnimalsCells
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Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency. Eur J Immunol. 1994 Aug; 24(8):1823-7.
Murphy WJ, Taub DD, Anver M, Conlon K, Oppenheim JJ, Kelvin DJ, Longo DL. PMID: 7519996.
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10 Fields:
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HumansAnimalsCells
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Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J Exp Med. 1994 Jul 01; 180(1):203-9.
Badolato R, Wang JM, Murphy WJ, Lloyd AR, Michiel DF, Bausserman LL, Kelvin DJ, Oppenheim JJ. PMID: 7516407; PMCID: PMC2191543.
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161 Fields:
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HumansAnimalsCells
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Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment. J Clin Invest. 1994 Jul; 94(1):293-300.
Taub DD, Tsarfaty G, Lloyd AR, Durum SK, Longo DL, Murphy WJ. PMID: 7518833; PMCID: PMC296309.
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15 Fields:
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HumansAnimalsCells
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Inhibition of human B-cell lymphoma growth by CD40 stimulation. Blood. 1994 May 15; 83(10):2787-94.
Funakoshi S, Longo DL, Beckwith M, Conley DK, Tsarfaty G, Tsarfaty I, Armitage RJ, Fanslow WC, Spriggs MK, Murphy WJ. PMID: 7514045.
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35 Fields:
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HumansAnimalsCells
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Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice. Blood. 1993 Oct 15; 82(8):2577-84.
Siefer AK, Longo DL, Harrison CL, Reynolds CW, Murphy WJ. PMID: 8400305.
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3 Fields:
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AnimalsCells
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Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts. J Clin Invest. 1993 Oct; 92(4):1918-24.
Murphy WJ, Back TC, Conlon KC, Komschlies KL, Ortaldo JR, Sayers TJ, Wiltrout RH, Longo DL. PMID: 8408644; PMCID: PMC288358.
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14 Fields:
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HumansAnimalsCells
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Natural killer cells and bone marrow transplantation. J Natl Cancer Inst. 1993 Sep 15; 85(18):1475-82.
Murphy WJ, Reynolds CW, Tiberghien P, Longo DL. PMID: 8360930.
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5 Fields:
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HumansAnimalsCells
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Differential effects of growth hormone and prolactin on murine T cell development and function. J Exp Med. 1993 Jul 01; 178(1):231-6.
Murphy WJ, Durum SK, Longo DL. PMID: 8315380; PMCID: PMC2191063.
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26 Fields:
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AnimalsCells
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Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency. J Immunol. 1993 Apr 15; 150(8 Pt 1):3634-42.
Murphy WJ, Conlon KC, Sayers TJ, Wiltrout RH, Back TC, Ortaldo JR, Longo DL. PMID: 8468492.
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8 Fields:
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HumansAnimalsCells
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Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo. J Immunol. 1992 Dec 15; 149(12):3851-7.
Murphy WJ, Durum SK, Longo DL. PMID: 1460277.
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23 Fields:
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AnimalsCells
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Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma. Brain Behav Immun. 1992 Dec; 6(4):355-64.
Murphy WJ, Durum SK, Anver M, Frazier M, Longo DL. PMID: 1336993.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine. Blood. 1992 Sep 15; 80(6):1443-7.
Murphy WJ, Tsarfaty G, Longo DL. PMID: 1520871.
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11 Fields:
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HumansAnimalsCells
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Hematopoietic growth-promoting effects of natural killer cells in mice in response to in vivo administration of human interleukin-2. J Natl Cancer Inst. 1992 Aug 05; 84(15):1195-200.
Murphy WJ, Longo DL. PMID: 1635088.
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AnimalsCells
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Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo. Blood. 1992 Aug 01; 80(3):670-7.
Murphy WJ, Keller JR, Harrison CL, Young HA, Longo DL. PMID: 1379086.
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13 Fields:
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AnimalsCells
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Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice. J Immunol. 1992 Jun 15; 148(12):3799-805.
Murphy WJ, Durum SK, Anver MR, Longo DL. PMID: 1602129.
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25 Fields:
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AnimalsCells
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Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions. Eur J Immunol. 1992 Jun; 22(6):1421-7.
Murphy WJ, Bennett M, Anver MR, Baseler M, Longo DL. PMID: 1534757.
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19 Fields:
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HumansAnimalsCells
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Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4481-5.
Murphy WJ, Durum SK, Longo DL. PMID: 1584780; PMCID: PMC49106.
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17 Fields:
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HumansAnimalsCells
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Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation. J Immunol. 1992 May 01; 148(9):2953-60.
Murphy WJ, Bennett M, Kumar V, Longo DL. PMID: 1573278.
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18 Fields:
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AnimalsCells
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Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans. Infect Immun. 1991 Sep; 59(9):3101-10.
Kozel TR, Wilson MA, Murphy JW. PMID: 1831795; PMCID: PMC258140.
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46 Fields:
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HumansAnimals
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Natural killer cells activated with interleukin 2 in vitro can be adoptively transferred and mediate hematopoietic histocompatibility-1 antigen-specific bone marrow rejection in vivo. Eur J Immunol. 1990 Aug; 20(8):1729-34.
Murphy WJ, Kumar V, Bennett M. PMID: 2209686.
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4 Fields:
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AnimalsCells
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An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells. J Immunol. 1990 May 01; 144(9):3305-11.
Murphy WJ, Kumar V, Cope JC, Bennett M. PMID: 2329274.
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6 Fields:
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AnimalsCells
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Immunobiology of bone marrow transplantation: studies using scid mice. Curr Top Microbiol Immunol. 1989; 152:251-8.
Murphy WJ, Kumar V, Bennett M. PMID: 2805793.
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PubMed Mentions:
2 Fields:
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AnimalsCells
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Rejection of bone marrow cells by irradiated mice: NK and T cells recognize different antigens. Transplant Proc. 1987 Dec; 19(6 Suppl 7):5-11.
Bennett M, Kumar V, Mikhael A, Murphy WJ, Rembecki RM, Sentman CL, David CS. PMID: 3321646.
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5 Fields:
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AnimalsCells
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Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized. J Exp Med. 1987 Nov 01; 166(5):1499-509.
Murphy WJ, Kumar V, Bennett M. PMID: 3316472; PMCID: PMC2189655.
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PubMed Mentions:
51 Fields:
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AnimalsCellsPHPublic Health
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Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection. J Exp Med. 1987 Apr 01; 165(4):1212-7.
Murphy WJ, Kumar V, Bennett M. PMID: 3549961; PMCID: PMC2188582.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells