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William J Murphy, PhD

Title(s)Professor, Dermatology
SchoolUniversity of California, Davis
AddressIRC #1612
CA 95817
Phone916-703-9397
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    Collapse Research 
    Collapse Research Activities and Funding
    Immunoregulatory and effector roles of natural killer cell subsets
    NIH/NHLBI R01HL140921Jan 1, 2018 - Dec 31, 2021
    Role: Principal Investigator
    Multispecies Comparison of the Impact of Obesity on GVHD/GVT
    NIH/NCI R01CA214048Jan 12, 2017 - Dec 31, 2021
    Role: Principal Investigator
    1 of 3 Interdisciplinary Collaboratory for Enhancing Translational Therapeutics Utilizing Biologically, Immunologically, and Metabollically Relevant Models of Breast Cancer
    NIH/NCI R01CA195904May 15, 2015 - Apr 30, 2018
    Role: Principal Investigator
    Radio-immunotherapy to Target Cancer Stem Cells in Solid Tumor Malignancies
    NIH/NCI R01CA189209Mar 6, 2015 - Feb 29, 2020
    Role: Principal Investigator
    Positive and Negative Regulation of Natural Killer Cells After BMT
    NIH/NHLBI R01HL089905Jul 18, 2007 - Nov 30, 2015
    Role: Principal Investigator
    Neuroendocrine Hormones to Promote Immune Reconstitution
    NIH/NIA R01AG022661Aug 1, 2003 - Jul 31, 2009
    Role: Principal Investigator
    Molecular targeting agents in GVHD/GVT: Role of cytokines and T cell subsets
    NIH/NCI R01CA102282Jul 1, 2003 - Apr 30, 2014
    Role: Principal Investigator
    Immunotherapy by CD40 stimulation and IL-2 against Cancer
    NIH/NCI R01CA095572Sep 1, 2002 - Jan 31, 2018
    Role: Principal Investigator
    Immunotherapy using NK cells to promote engraftment
    NIH/NCI R01CA093527Sep 1, 2002 - Aug 31, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Minimal PD-1 expression in mouse and human NK cells under diverse conditions. J Clin Invest. 2020 Jun 01; 130(6):3051-3068. Judge SJ, Dunai C, Aguilar EG, Vick SC, Sturgill IR, Khuat LT, Stoffel KM, Van Dyke J, Longo DL, Darrow MA, Anderson SK, Blazar BR, Monjazeb AM, Serody JS, Canter RJ, Murphy WJ. PMID: 32134744.
      View in: PubMed   Mentions: 4     Fields:    
    2. Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD. Nat Rev Clin Oncol. 2020 Aug; 17(8):475-492. Blazar BR, Hill GR, Murphy WJ. PMID: 32313224.
      View in: PubMed   Mentions: 1     Fields:    
    3. Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer. PLoS One. 2020; 15(2):e0224775. Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ. PMID: 32084139.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCellsCTClinical Trials
    4. Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence. Front Cell Infect Microbiol. 2020; 10:49. Judge SJ, Murphy WJ, Canter RJ. PMID: 32117816.
      View in: PubMed   Mentions: 2     Fields:    
    5. Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease. Blood. 2020 01 02; 135(1):28-40. Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, Murphy WJ, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Dahlberg C, Miller AT, Blazar BR. PMID: 31697815.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. Moving forward to address key unanswered questions on targeting PD-1/PD-L1 in cancer: limitations in preclinical models and the need to incorporate human modifying factors. J Immunother Cancer. 2019 11 07; 7(1):291. Le CT, Murphy WJ. PMID: 31699145.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD. Blood. 2019 11 07; 134(19):1670-1682. Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR. PMID: 31533918.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. JCI Insight. 2019 10 03; 4(19). Saha A, Taylor PA, Lees CJ, Panoskaltsis-Mortari A, Osborn MJ, Feser CJ, Thangavelu G, Melchinger W, Refaeli Y, Hill GR, Munn DH, Murphy WJ, Serody JS, Maillard I, Kreymborg K, van den Brink M, Dong C, Huang S, Zang X, Allison JP, Zeiser R, Blazar BR. PMID: 31578305.
      View in: PubMed   Mentions: 1     Fields:    
    9. Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway. JCI Insight. 2019 06 18; 5. Alvarez M, Simonetta F, Baker J, Pierini A, Wenokur AS, Morrison AR, Murphy WJ, Negrin RS. PMID: 31211693.
      View in: PubMed   Mentions: 7     Fields:    
    10. Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma. Vet Comp Oncol. 2019 Sep; 17(3):242-252. Withers SS, York D, Choi JW, Woolard KD, Laufer-Amorim R, Sparger EE, Burton JH, McSorley SJ, Monjazeb AM, Murphy WJ, Canter RJ, Rebhun RB. PMID: 30684301.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy. JAMA. 2019 Apr 02; 321(13):1247-1248. Murphy WJ, Longo DL. PMID: 30882850.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Targeting PI3Kd function for amelioration of murine chronic graft-versus-host disease. Am J Transplant. 2019 06; 19(6):1820-1830. Paz K, Flynn R, Du J, Tannheimer S, Johnson AJ, Dong S, Stark AK, Okkenhaug K, Panoskaltsis-Mortari A, Sage PT, Sharpe AH, Luznik L, Ritz J, Soiffer RJ, Cutler CS, Koreth J, Antin JH, Miklos DB, MacDonald KP, Hill GR, Maillard I, Serody JS, Murphy WJ, Munn DH, Feser C, Zaiken M, Vanhaesebroeck B, Turka LA, Byrd JC, Blazar BR. PMID: 30748099.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    13. Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. J Immunol. 2019 05 01; 202(9):2795-2805. Thangavelu G, Lee YC, Loschi M, Schaechter KM, Feser CJ, Koehn BH, Nowak EC, Zeiser R, Serody JS, Murphy WJ, Munn DH, Chambon P, Noelle RJ, Blazar BR. PMID: 30885956.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. Cancers (Basel). 2019 Jan 14; 11(1). Luna JI, Grossenbacher SK, Sturgill IR, Ames E, Judge SJ, Bouzid LA, Darrow MA, Murphy WJ, Canter RJ. PMID: 30646520.
      View in: PubMed   Mentions:
    15. The complicated effects of  obesity on cancer and immunotherapy. Immunotherapy. 2019 01; 11(1):11-14. Wang Z, Monjazeb AM, Murphy WJ. PMID: 30702013.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    16. Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. Nat Med. 2019 01; 25(1):141-151. Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. PMID: 30420753.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    17. Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease. Blood. 2019 01 03; 133(1):94-99. Paz K, Flynn R, Du J, Qi J, Luznik L, Maillard I, MacDonald KP, Hill GR, Serody JS, Murphy WJ, Sage PT, Sharpe AH, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Bradner JE, Melnick AM, Blazar BR. PMID: 30279226.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. Association of macrophage and lymphocyte infiltration with outcome in canine osteosarcoma. Vet Comp Oncol. 2019 Mar; 17(1):49-60. Withers SS, Skorupski KA, York D, Choi JW, Woolard KD, Laufer-Amorim R, Sparger EE, Rodriguez CO, McSorley SJ, Monjazeb AM, Murphy WJ, Canter RJ, Rebhun RB. PMID: 30156029.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell. J Clin Invest. 2018 10 01; 128(10):4251-4253. Dunai C, Murphy WJ. PMID: 30198909.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    20. A possible new pathway in natural killer cell activation also reveals the difficulty in determining human NK cell function in cancer. J Immunother Cancer. 2018 08 07; 6(1):79. Canter RJ, Murphy WJ. PMID: 30086799.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. Theranostics. 2018; 8(13):3611-3628. Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW. PMID: 30026870.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    22. Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. Dev Comp Immunol. 2018 10; 87:64-74. Withers SS, Moore PF, Chang H, Choi JW, McSorley SJ, Kent MS, Monjazeb AM, Canter RJ, Murphy WJ, Sparger EE, Rebhun RB. PMID: 29859828.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    23. Obesity as an immune-modifying factor in cancer immunotherapy. J Leukoc Biol. 2018 09; 104(3):487-497. Canter RJ, Le CT, Beerthuijzen JMT, Murphy WJ. PMID: 29762866.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    24. Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site. Int J Radiat Oncol Biol Phys. 2018 08 01; 101(5):1259-1270. McGee HM, Daly ME, Azghadi S, Stewart SL, Oesterich L, Schlom J, Donahue R, Schoenfeld JD, Chen Q, Rao S, Fragoso RC, Valicenti RK, Canter RJ, Maverakis EM, Murphy WJ, Kelly K, Monjazeb AM. PMID: 29891204.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    25. Improving classification of melanocytic nevi: Association of BRAF V600E expression with distinct histomorphologic features. J Am Acad Dermatol. 2018 Aug; 79(2):221-229. Kiuru M, Tartar DM, Qi L, Chen D, Yu L, Konia T, McPherson JD, Murphy WJ, Fung MA. PMID: 29653212.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Obesity induced T cell dysfunction and implications for cancer immunotherapy. Curr Opin Immunol. 2018 04; 51:181-186. Aguilar EG, Murphy WJ. PMID: 29655021.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    27. Donor HSCs with a preexisting ASXL1-mutation led to the development of FLT3-ITD positive AML in the donor and FLT3-ITD negative AML in the recipient after unrelated transplant. Bone Marrow Transplant. 2018 04; 53(4):499-502. Liu Z, Liu H, Shi M, Ahmed HAW, Huo L, Zhang Y, Kong D, Wen M, Wang F, Chen M, Murphy WJ, Sun K. PMID: 29330388.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Making a Better Hematopoietic Stem Cell - Timing Is Everything. N Engl J Med. 2018 01 04; 378(1):89-91. Murphy WJ. PMID: 29298159.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    29. Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas. J Surg Res. 2018 03; 223:207-214. Henderson T, Chen M, Darrow MA, Li CS, Chiu CL, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 29433875.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    30. Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial. J Immunother Cancer. 2017 Dec 19; 5(1):98. Canter RJ, Grossenbacher SK, Foltz JA, Sturgill IR, Park JS, Luna JI, Kent MS, Culp WTN, Chen M, Modiano JF, Monjazeb AM, Lee DA, Murphy WJ. PMID: 29254507.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    31. Range-Wide Snow Leopard Phylogeography Supports Three Subspecies. J Hered. 2017 Sep 01; 108(6):597-607. Janecka JE, Zhang Y, Li D, Munkhtsog B, Bayaraa M, Galsandorj N, Wangchuk TR, Karmacharya D, Li J, Lu Z, Uulu KZ, Gaur A, Kumar S, Kumar K, Hussain S, Muhammad G, Jevit M, Hacker C, Burger P, Wultsch C, Janecka MJ, Helgen K, Murphy WJ, Jackson R. PMID: 28498961.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    32. Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment. Am J Pathol. 2017 Aug; 187(8):1800-1813. Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY. PMID: 28711154.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    33. Therapeutic Efficacy of Fresh, Allogeneic Mesenchymal Stem Cells for Severe Refractory Feline Chronic Gingivostomatitis. Stem Cells Transl Med. 2017 08; 6(8):1710-1722. Arzi B, Clark KC, Sundaram A, Spriet M, Verstraete FJM, Walker NJ, Loscar MR, Fazel N, Murphy WJ, Vapniarsky N, Borjesson DL. PMID: 28618186.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    34. Licensing delineates helper and effector NK cell subsets during viral infection. JCI Insight. 2017 May 18; 2(10). Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ. PMID: 28515356.
      View in: PubMed   Mentions: 8     Fields:    
    35. Leveraging natural killer cells for cancer immunotherapy. Immunotherapy. 2017 05; 9(6):487-497. Grossenbacher SK, Aguilar EG, Murphy WJ. PMID: 28472904.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    36. Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control. Int J Radiat Oncol Biol Phys. 2017 10 01; 99(2):362-373. Baird JR, Monjazeb AM, Shah O, McGee H, Murphy WJ, Crittenden MR, Gough MJ. PMID: 28871985.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    37. Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy. J Immunother Cancer. 2017; 5:33. Sckisel GD, Mirsoian A, Minnar CM, Crittenden M, Curti B, Chen JQ, Blazar BR, Borowsky AD, Monjazeb AM, Murphy WJ. PMID: 28428882.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    38. Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols. JCI Insight. 2017 03 23; 2(6):e90521. Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW. PMID: 28352658.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    39. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017 03 20; 8(1):69. Clark KC, Fierro FA, Ko EM, Walker NJ, Arzi B, Tepper CG, Dahlenburg H, Cicchetto A, Kol A, Marsh L, Murphy WJ, Fazel N, Borjesson DL. PMID: 28320483.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    40. The proportion of circulating CD45RO+CD8+ memory T cells is correlated with clinical response in melanoma patients treated with ipilimumab. Eur J Cancer. 2017 04; 75:268-279. Tietze JK, Angelova D, Heppt MV, Reinholz M, Murphy WJ, Spannagl M, Ruzicka T, Berking C. PMID: 28242504.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    41. Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy. Expert Opin Biol Ther. 2017 03; 17(3):313-324. Luna JI, Grossenbacher SK, Murphy WJ, Canter RJ. PMID: 27960589.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    42. Canine cancer immunotherapy studies: linking mouse and human. J Immunother Cancer. 2016; 4:97. Park JS, Withers SS, Modiano JF, Kent MS, Chen M, Luna JI, Culp WTN, Sparger EE, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. PMID: 28031824.
      View in: PubMed   Mentions: 19     Fields:    
    43. Being "penny-wise but pound foolish" in cancer immunotherapy research: the urgent need for mouse cancer models to reflect human modifying factors. J Immunother Cancer. 2016; 4:88. Murphy WJ. PMID: 28031818.
      View in: PubMed   Mentions: 1     Fields:    
    44. Therapeutic Effects of a NEDD8-Activating Enzyme Inhibitor, Pevonedistat, on Sclerodermatous Graft-versus-Host Disease in Mice. Biol Blood Marrow Transplant. 2017 01; 23(1):30-37. Pai CS, Khuat LT, Chen M, Murphy WJ, Abedi M. PMID: 27815049.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    45. Immunoregulatory pathways following strong inflammatory processes markedly impair CD4+ T cell responses. Hum Vaccin Immunother. 2016 09; 12(9):2249-52. Minnar CM, Murphy WJ. PMID: 27409155.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    46. Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner. Blood. 2016 08 18; 128(7):1013-7. McDonald-Hyman C, Flynn R, Panoskaltsis-Mortari A, Peterson N, MacDonald KP, Hill GR, Luznik L, Serody JS, Murphy WJ, Maillard I, Munn DH, Turka LA, Koreth J, Cutler CS, Soiffer RJ, Antin JH, Ritz J, Blazar BR. PMID: 27385791.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    47. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016 07 01; 126(7):2642-60. Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR. PMID: 27294527.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    48. High fluence light emitting diode-generated red light modulates characteristics associated with skin fibrosis. J Biophotonics. 2016 12; 9(11-12):1167-1179. Mamalis A, Koo E, Garcha M, Murphy WJ, Isseroff RR, Jagdeo J. PMID: 27174640.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    49. Natural killer cell immunotherapy to target stem-like tumor cells. J Immunother Cancer. 2016; 4:19. Grossenbacher SK, Canter RJ, Murphy WJ. PMID: 27096096.
      View in: PubMed   Mentions: 8     Fields:    
    50. Immune targeting of cancer stem cells in gastrointestinal oncology. J Gastrointest Oncol. 2016 Apr; 7(Suppl 1):S1-S10. Canter RJ, Grossenbacher SK, Ames E, Murphy WJ. PMID: 27034806.
      View in: PubMed   Mentions:
    51. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood. 2016 04 28; 127(17):2144-54. Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, Aguilar EG, Murphy WJ, Maillard I, Munn D, Koreth J, Cutler CS, Antin JH, Ritz J, Waksal SD, Zanin-Zhorov A, Blazar BR. PMID: 26983850.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    52. Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies. Clin Cancer Res. 2016 Sep 01; 22(17):4328-40. Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ. PMID: 26979392.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    53. Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment. Blood. 2016 Mar 03; 127(9):1202-5. Alvarez M, Sun K, Murphy WJ. PMID: 26738538.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    54. Preclinical modeling of hematopoietic stem cell transplantation - advantages and limitations. FEBS J. 2016 05; 283(9):1595-606. Stolfi JL, Pai CC, Murphy WJ. PMID: 26640088.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    55. Therapeutic Efficacy of Fresh, Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats. Stem Cells Transl Med. 2016 Jan; 5(1):75-86. Arzi B, Mills-Ko E, Verstraete FJ, Kol A, Walker NJ, Badgley MR, Fazel N, Murphy WJ, Vapniarsky N, Borjesson DL. PMID: 26582907.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    56. Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity. Cancer Res. 2015 Dec 15; 75(24):5260-72. Shanker A, Pellom ST, Dudimah DF, Thounaojam MC, de Kluyver RL, Brooks AD, Yagita H, McVicar DW, Murphy WJ, Longo DL, Sayers TJ. PMID: 26494122.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    57. CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery. J Control Release. 2015 Dec 28; 220(Pt A):253-264. Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW. PMID: 26471394.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    58. Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration. PLoS One. 2015; 10(10):e0140628. Mamalis A, Koo E, Isseroff RR, Murphy W, Jagdeo J. PMID: 26488596.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    59. Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy. Cancer Immunol Immunother. 2015 Dec; 64(12):1541-52. Sckisel GD, Mirsoian A, Bouchlaka MN, Tietze JK, Chen M, Blazar BR, Murphy WJ. PMID: 26423422.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    60. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016 06 02; 35(22):2932-47. Yokdang N, Hatakeyama J, Wald JH, Simion C, Tellez JD, Chang DZ, Swamynathan MM, Chen M, Murphy WJ, Carraway Iii KL, Sweeney C. PMID: 26387542.
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    61. NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype. J Immunol. 2015 Oct 15; 195(8):4010-9. Ames E, Canter RJ, Grossenbacher SK, Mac S, Chen M, Smith RC, Hagino T, Perez-Cunningham J, Sckisel GD, Urayama S, Monjazeb AM, Fragoso RC, Sayers TJ, Murphy WJ. PMID: 26363055.
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    62. Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer. Oncoimmunology. 2016 Feb; 5(2):e1075114. Mall C, Sckisel GD, Proia DA, Mirsoian A, Grossenbacher SK, Pai CS, Chen M, Monjazeb AM, Kelly K, Blazar BR, Murphy WJ. PMID: 27057446.
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    63. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 2015 Sep 24; 126(13):1621-8. Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, Blazar BR. PMID: 26265697.
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    64. Models to Study NK Cell Biology and Possible Clinical Application. Curr Protoc Immunol. 2015 Aug 03; 110:14.37.1-14.37.14. Zamora AE, Grossenbacher SK, Aguilar EG, Murphy WJ. PMID: 26237009.
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    65. Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity. Immunity. 2015 Aug 18; 43(2):240-50. Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. PMID: 26231116.
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    66. Enhanced targeting of stem-like solid tumor cells with radiation and natural killer cells. Oncoimmunology. 2015 Sep; 4(9):e1036212. Ames E, Canter RJ, Grossenbacher SK, Mac S, Smith RC, Monjazeb AM, Chen M, Murphy WJ. PMID: 26405602.
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    67. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 2015 Jun 25; 125(26):4085-94. Flynn R, Allen JL, Luznik L, MacDonald KP, Paz K, Alexander KA, Vulic A, Du J, Panoskaltsis-Mortari A, Taylor PA, Poe JC, Serody JS, Murphy WJ, Hill GR, Maillard I, Koreth J, Cutler CS, Soiffer RJ, Antin JH, Ritz J, Chao NJ, Clynes RA, Sarantopoulos S, Blazar BR. PMID: 25852057.
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    68. Attenuated age-impact on systemic inflammatory markers in the presence of a metabolic burden. PLoS One. 2015; 10(3):e0121947. Erdembileg A, Mirsoian A, Enkhmaa B, Zhang W, Beckett LA, Murphy WJ, Berglund LF. PMID: 25815855.
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    69. B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality. Blood. 2015 05 21; 125(21):3335-46. Veenstra RG, Flynn R, Kreymborg K, McDonald-Hyman C, Saha A, Taylor PA, Osborn MJ, Panoskaltsis-Mortari A, Schmitt-Graeff A, Lieberknecht E, Murphy WJ, Serody JS, Munn DH, Freeman GJ, Allison JP, Mak TW, van den Brink M, Zeiser R, Blazar BR. PMID: 25814530.
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    70. Reprint of: Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biol Blood Marrow Transplant. 2015 Feb; 21(2 Suppl):S19-24. Boeckh M, Murphy WJ, Peggs KS. PMID: 25620648.
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    71. Obesity and cancer immunotherapy toxicity. Immunotherapy. 2015; 7(4):319-22. Mirsoian A, Murphy WJ. PMID: 25917623.
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    72. Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biol Blood Marrow Transplant. 2015 Jan; 21(1):24-9. Boeckh M, Murphy WJ, Peggs KS. PMID: 25452035.
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    73. Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. J Exp Med. 2014 Nov 17; 211(12):2373-83. Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ. PMID: 25366964.
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    74. Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma. BMC Cancer. 2014 Oct 10; 14:756. Canter RJ, Ames E, Mac S, Grossenbacher SK, Chen M, Li CS, Borys D, Smith RC, Tellez J, Sayers TJ, Monjazeb AM, Murphy WJ. PMID: 25301268.
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    75. Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. J Clin Invest. 2014 Nov; 124(11):4867-76. Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR. PMID: 25271622.
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    76. Bringing out the DCs' softer side in GVHD. Blood. 2014 Sep 18; 124(12):1852-3. Murphy WJ. PMID: 25606629.
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    77. The authors' reply. Transplantation. 2014 Sep 15; 98(5):e39-40. Ames E, Murphy WJ. PMID: 25171530.
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    78. Using a web-based nutrition algorithm in hemodialysis patients. J Ren Nutr. 2015 Jan; 25(1):6-16. Steiber AL, León JB, Hand RK, Murphy WJ, Fouque D, Parrott JS, Kalantar-Zadeh K, Cuppari L. PMID: 25193109.
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    79. Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. PLoS One. 2014; 9(8):e102709. Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. PMID: 25119341.
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    80. Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels. Biol Blood Marrow Transplant. 2014 Dec; 20(12):1899-904. Pai CC, Hsiao HH, Sun K, Chen M, Hagino T, Tellez J, Mall C, Blazar BR, Monjazeb A, Abedi M, Murphy WJ. PMID: 25064746.
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    81. Treatment of chronic graft-versus-host disease with bortezomib. Blood. 2014 Sep 04; 124(10):1677-88. Pai CC, Chen M, Mirsoian A, Grossenbacher SK, Tellez J, Ames E, Sun K, Jagdeo J, Blazar BR, Murphy WJ, Abedi M. PMID: 25009225.
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    82. Increased antitumor effects using IL-2 with anti-TGF-ß reveals competition between mouse NK and CD8 T cells. J Immunol. 2014 Aug 15; 193(4):1709-16. Alvarez M, Bouchlaka MN, Sckisel GD, Sungur CM, Chen M, Murphy WJ. PMID: 25000978.
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    83. Natural killer cell subsets differentially reject embryonic stem cells based on licensing. Transplantation. 2014 May 27; 97(10):992-8. Perez-Cunningham J, Ames E, Smith RC, Peter AK, Naidu R, Nolta JA, Murphy WJ. PMID: 24704665.
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    84. Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 2014 Jun 19; 123(25):3988-98. Flynn R, Du J, Veenstra RG, Reichenbach DK, Panoskaltsis-Mortari A, Taylor PA, Freeman GJ, Serody JS, Murphy WJ, Munn DH, Sarantopoulos S, Luznik L, Maillard I, Koreth J, Cutler C, Soiffer RJ, Antin JH, Ritz J, Dubovsky JA, Byrd JC, MacDonald KP, Hill GR, Blazar BR. PMID: 24820310.
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    85. Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/aCD40 therapy. J Immunol. 2014 Jun 15; 192(12):5821-9. Weiss JM, Subleski JJ, Back T, Chen X, Watkins SK, Yagita H, Sayers TJ, Murphy WJ, Wiltrout RH. PMID: 24808361.
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    86. Positive and negative regulation by NK cells in cancer. Crit Rev Oncog. 2014; 19(1-2):57-66. Sungur CM, Murphy WJ. PMID: 24941373.
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    87. Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. Clin Exp Immunol. 2014 Jan; 175(1):79-91. Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ. PMID: 23937663.
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    88. Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models. Oncoimmunology. 2013 Dec 01; 2(12):e27186. Bouchlaka MN, Murphy WJ. PMID: 24498569.
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    89. Cellular and molecular pathways in the tumor immunoenvironment: 3rd Cancer Immunotherapy and Immunomonitoring (CITIM) meeting, 22-25 April 2013, Krakow, Poland. Cancer Immunol Immunother. 2014 Jan; 63(1):73-80. Shurin MR, Umansky V, Malyguine A, Hurwitz AA, Apte RN, Whiteside T, Jewett A, Thanavala Y, Murphy WJ. PMID: 24271210.
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    90. Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. J Exp Med. 2013 Oct 21; 210(11):2223-37. Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. PMID: 24081947.
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    91. The path(way) less traveled. Blood. 2013 Sep 19; 122(12):1996-7. Abedi M, Murphy WJ. PMID: 24052539.
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    92. Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood. 2013 Oct 24; 122(17):3062-73. Saha A, Aoyama K, Taylor PA, Koehn BH, Veenstra RG, Panoskaltsis-Mortari A, Munn DH, Murphy WJ, Azuma M, Yagita H, Fife BT, Sayegh MH, Najafian N, Socie G, Ahmed R, Freeman GJ, Sharpe AH, Blazar BR. PMID: 24030385.
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    93. Advantages and clinical applications of natural killer cells in cancer immunotherapy. Cancer Immunol Immunother. 2014 Jan; 63(1):21-8. Ames E, Murphy WJ. PMID: 23989217.
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    94. Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013 Oct; 19(10):1446-52. Barao I, Wright PW, Sungur CM, Anderson SK, Redelman D, Murphy WJ. PMID: 23911940.
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    95. Immunoediting and antigen loss: overcoming the achilles heel of immunotherapy with antigen non-specific therapies. Front Oncol. 2013; 3:197. Monjazeb AM, Zamora AE, Grossenbacher SK, Mirsoian A, Sckisel GD, Murphy WJ. PMID: 23898464.
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    97. Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry. Protein Sci. 2013 Aug; 22(8):1078-86. He W, Luo J, Bourguet F, Xing L, Yi SK, Gao T, Blanchette C, Henderson PT, Kuhn E, Malfatti M, Murphy WJ, Cheng RH, Lam KS, Coleman MA. PMID: 23754445.
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    98. Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 2013 Sep 19; 122(12):2125-34. Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Socié G, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, Chandraratna RA, Dmitrovsky E, Guo Y, Noelle RJ, Blazar BR. PMID: 23814022.
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    99. Contrasting effects of anti-Ly49A due to MHC class I cis binding on NK cell-mediated allogeneic bone marrow cell resistance. J Immunol. 2013 Jul 15; 191(2):688-98. Alvarez M, Sungur CM, Ames E, Anderson SK, Pomeroy C, Murphy WJ. PMID: 23752612.
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    100. Of mice and men. Biol Blood Marrow Transplant. 2013 Aug; 19(8):1140-1. Murphy WJ. PMID: 23680473.
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    101. Murine natural killer cell licensing and regulation by T regulatory cells in viral responses. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7401-6. Sungur CM, Tang-Feldman YJ, Ames E, Alvarez M, Chen M, Longo DL, Pomeroy C, Murphy WJ. PMID: 23589894.
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    102. Utilization of mouse models to decipher natural killer cell biology and potential clinical applications. Hematology Am Soc Hematol Educ Program. 2013; 2013:227-33. Sungur CM, Murphy WJ. PMID: 24319185.
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    103. Impact of Obesity and Aging on the Tumor Immuno-Environment. . 2013 Jan 1; 223-250. Annie Mirsoian, Gail D. Sckisel, Anthony E. Zamora, William J. Murphy. .
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    105. Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells. Oncoimmunology. 2012 Oct 01; 1(7):1208-1210. Sckisel GD, Murphy WJ. PMID: 23170282.
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    107. The role of antigen-specific and non-specific immunotherapy in the treatment of cancer. J Immunotoxicol. 2012 Jul-Sep; 9(3):248-58. Monjazeb AM, Hsiao HH, Sckisel GD, Murphy WJ. PMID: 22734880.
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    108. Advances in graft-versus-host disease biology and therapy. Nat Rev Immunol. 2012 May 11; 12(6):443-58. Blazar BR, Murphy WJ, Abedi M. PMID: 22576252.
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    109. Autoimmune T cells lured to a FASL web of death by MSCs. Cell Stem Cell. 2012 May 04; 10(5):485-7. Murphy WJ, Nolta JA. PMID: 22560070.
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    110. Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy. Blood. 2012 Mar 29; 119(13):3073-83. Tietze JK, Wilkins DE, Sckisel GD, Bouchlaka MN, Alderson KL, Weiss JM, Ames E, Bruhn KW, Craft N, Wiltrout RH, Longo DL, Lanier LL, Blazar BR, Redelman D, Murphy WJ. PMID: 22251483.
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    111. NK cells--from bench to clinic. Biol Blood Marrow Transplant. 2012 Jan; 18(1 Suppl):S2-7. Murphy WJ, Parham P, Miller JS. PMID: 22226108.
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    112. Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensing. Blood. 2012 Feb 09; 119(6):1590-8. Sun K, Alvarez M, Ames E, Barao I, Chen M, Longo DL, Redelman D, Murphy WJ. PMID: 22184406.
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    113. Defining the critical hurdles in cancer immunotherapy. J Transl Med. 2011 Dec 14; 9:214. Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG, Finke JH, Galon J, Gollob JA, Gouttefangeas C, Grizzi F, Guida M, Håkansson L, Hege K, Herberman RB, Hodi FS, Hoos A, Huber C, Hwu P, Imai K, Jaffee EM, Janetzki S, June CH, Kalinski P, Kaufman HL, Kawakami K, Kawakami Y, Keilholtz U, Khleif SN, Kiessling R, Kotlan B, Kroemer G, Lapointe R, Levitsky HI, Lotze MT, Maccalli C, Maio M, Marschner JP, Mastrangelo MJ, Masucci G, Melero I, Melief C, Murphy WJ, Nelson B, Nicolini A, Nishimura MI, Odunsi K, Ohashi PS, O'Donnell-Tormey J, Old LJ, Ottensmeier C, Papamichail M, Parmiani G, Pawelec G, Proietti E, Qin S, Rees R, Ribas A, Ridolfi R, Ritter G, Rivoltini L, Romero PJ, Salem ML, Scheper RJ, Seliger B, Sharma P, Shiku H, Singh-Jasuja H, Song W, Straten PT, Tahara H, Tian Z, van Der Burg SH, von Hoegen P, Wang E, Welters MJ, Winter H, Withington T, Wolchok JD, Xiao W, Zitvogel L, Zwierzina H, Marincola FM, Gajewski TF, Wigginton JM, Disis ML. PMID: 22168571.
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    114. The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice. Biol Blood Marrow Transplant. 2012 Mar; 18(3):396-405. Ames E, Harouna S, Meyer C, Welniak LA, Murphy WJ. PMID: 22100978.
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    115. Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans. Blood. 2012 Feb 09; 119(6):1570-80. Srinivasan M, Flynn R, Price A, Ranger A, Browning JL, Taylor PA, Ritz J, Antin JH, Murphy WJ, Luznik L, Shlomchik MJ, Panoskaltsis-Mortari A, Blazar BR. PMID: 22072556.
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    116. Antigen-specific versus antigen-nonspecific immunotherapeutic approaches for human melanoma: the need for integration for optimal efficacy? Int Rev Immunol. 2011 Oct-Dec; 30(5-6):238-93. Tietze JK, Sckisel GD, Hsiao HH, Murphy WJ. PMID: 22053969.
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    117. Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2011 Dec; 17(12):1754-64. Barao I, Alvarez M, Redelman D, Weiss JM, Ortaldo JR, Wiltrout RH, Murphy WJ. PMID: 21906575.
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    118. Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC. Blood. 2011 Jun 30; 117(26):7032-41. Barao I, Alvarez M, Ames E, Orr MT, Stefanski HE, Blazar BR, Lanier LL, Anderson SK, Redelman D, Murphy WJ. PMID: 21498673.
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    119. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood. 2011 Apr 28; 117(17):4501-10. Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy WJ, Azuma M, Anderson AC, Kuchroo VK, Blazar BR. PMID: 21385853.
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    120. Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. Blood. 2011 Mar 24; 117(12):3268-76. Coghill JM, Sarantopoulos S, Moran TP, Murphy WJ, Blazar BR, Serody JS. PMID: 21245483.
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    121. Americans hear as well or better today compared with 40 years ago: hearing threshold levels in the unscreened adult population of the United States, 1959-1962 and 1999-2004. Ear Hear. 2010 Dec; 31(6):725-34. Hoffman HJ, Dobie RA, Ko CW, Themann CL, Murphy WJ. PMID: 20683190.
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    122. Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy. J Exp Med. 2010 Oct 25; 207(11):2455-67. Weiss JM, Ridnour LA, Back T, Hussain SP, He P, Maciag AE, Keefer LK, Murphy WJ, Harris CC, Wink DA, Wiltrout RH. PMID: 20921282.
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    123. Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Blood. 2010 Oct 07; 116(14):2484-93. Zhou Q, Munger ME, Highfill SL, Tolar J, Weigel BJ, Riddle M, Sharpe AH, Vallera DA, Azuma M, Levine BL, June CH, Murphy WJ, Munn DH, Blazar BR. PMID: 20570856.
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    124. Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways. Curr Opin Pharmacol. 2010 Aug; 10(4):408-24. Taub DD, Murphy WJ, Longo DL. PMID: 20595009.
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    125. Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects. Immunotherapy. 2010 May; 2(3):399-418. Bouchlaka MN, Redelman D, Murphy WJ. PMID: 20635904.
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    126. The triterpenoid CDDO-Me delays murine acute graft-versus-host disease with the preservation of graft-versus-tumor effects after allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2010 Jun; 16(6):739-50. Li M, Sun K, Redelman D, Welniak LA, Murphy WJ. PMID: 20338256.
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    127. Hematopoietic progenitor cell regulation by CD4+CD25+ T cells. Blood. 2010 Jun 10; 115(23):4934-43. Urbieta M, Barao I, Jones M, Jurecic R, Panoskaltsis-Mortari A, Blazar BR, Murphy WJ, Levy RB. PMID: 20200356.
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    128. Activated allogeneic NK cells as suppressors of alloreactive responses. Biol Blood Marrow Transplant. 2010 Jun; 16(6):772-81. Hu B, He Y, Wu Y, Bao G, Liu H, Welniak LA, Murphy WJ. PMID: 20197103.
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    129. 'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection. Nat Immunol. 2010 Apr; 11(4):321-7. Orr MT, Murphy WJ, Lanier LL. PMID: 20190757.
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    130. NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction. Biol Blood Marrow Transplant. 2010 May; 16(5):565-86. Miller JS, Warren EH, van den Brink MR, Ritz J, Shlomchik WD, Murphy WJ, Barrett AJ, Kolb HJ, Giralt S, Bishop MR, Blazar BR, Falkenburg JH. PMID: 20152921.
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    131. Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses. Adv Exp Med Biol. 2010; 684:155-65. Alderson KL, Murphy WJ. PMID: 20795547.
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    132. Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation. . 2010 Jan 1; 199-219. Deborah L. S. Goetz, William J. Murphy. .
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    133. Blood stem cell transplantation in older patients. Biol Blood Marrow Transplant. 2009 Dec; 15(12):1638-9. Murphy WJ, Artz AS, Champlin RE, Koreth J, Longo DL, van den Brink MR. PMID: 19911448.
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    134. Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a review. Biol Blood Marrow Transplant. 2009 Dec; 15(12):1502-12. Koreth J, Alyea EP, Murphy WJ, Welniak LA. PMID: 19896073.
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    135. Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19455-60. Weiss JM, Back TC, Scarzello AJ, Subleski JJ, Hall VL, Stauffer JK, Chen X, Micic D, Alderson K, Murphy WJ, Wiltrout RH. PMID: 19892741.
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    136. Utilization of Biocompatible Ferrous Particles for a New Cancer Therapy. . 2009 Jun 17; 565-566. Cahit A. Evrensel, Lisbeth A. Welniak, Alan Fuchs, Jigar Patel, William J. Murphy, Faramarz Gordaninejad. .
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    137. Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease. Am J Transplant. 2009 Mar; 9(3):452-62. O'Shaughnessy MJ, Vogtenhuber C, Sun K, Sitcheran R, Baldwin AS, Murphy WJ, Dang L, Jaffee B, Palmer E, Serody JS, Blazar BR. PMID: 19260829.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    138. Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition. Clin Exp Immunol. 2009 Mar; 155(3):504-13. Ames E, Hallett WH, Murphy WJ. PMID: 19220837.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    139. Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses. Adv Exp Med Biol. 2009; 633:81-9. Alderson KL, Murphy WJ. PMID: 19209683.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    140. CD40 Stimulation and Antitumor Effects. . 2009 Jan 1; 227-239. Danice E. C. Wilkins, William J. Murphy. .
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    141. A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae. Genomics. 2009 Apr; 93(4):299-304. Davis BW, Raudsepp T, Pearks Wilkerson AJ, Agarwala R, Schäffer AA, Houck M, Chowdhary BP, Murphy WJ. PMID: 18951970.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    142. Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses. Biol Blood Marrow Transplant. 2008 Oct; 14(10):1088-1099. Hallett WHD, Ames E, Álvarez M, Barao I, Taylor PA, Blazar BR, Murphy WJ. PMID: 18804038.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    143. Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease. Expert Opin Pharmacother. 2008 Sep; 9(13):2305-16. Li M, Sun K, Welniak LA, Murphy WJ. PMID: 18710355.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    144. TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection. Blood. 2008 Oct 15; 112(8):3508-16. Taylor PA, Ehrhardt MJ, Lees CJ, Panoskaltsis-Mortari A, Krieg AM, Sharpe AH, Murphy WJ, Serody JS, Hemmi H, Akira S, Levy RB, Blazar BR. PMID: 18614760.
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    145. CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus. J Immunol. 2008 Jul 01; 181(1):47-61. Puliaev R, Puliaeva I, Welniak LA, Ryan AE, Haas M, Murphy WJ, Via CS. PMID: 18566369.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    146. Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation. Blood. 2008 Aug 15; 112(4):1522-9. Sun K, Li M, Sayers TJ, Welniak LA, Murphy WJ. PMID: 18539902.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    147. Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody. J Natl Cancer Inst. 2008 May 07; 100(9):649-62. Shanker A, Brooks AD, Tristan CA, Wine JW, Elliott PJ, Yagita H, Takeda K, Smyth MJ, Murphy WJ, Sayers TJ. PMID: 18445820.
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    148. Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network. Cell Immunol. 2008 Mar-Apr; 252(1-2):111-21. Redelman D, Welniak LA, Taub D, Murphy WJ. PMID: 18313040.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    149. Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy. J Immunol. 2008 Mar 01; 180(5):2981-8. Alderson KL, Zhou Q, Berner V, Wilkins DE, Weiss JM, Blazar BR, Welniak LA, Wiltrout RH, Redelman D, Murphy WJ. PMID: 18292520.
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    150. Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition. J Immunol. 2008 Jan 01; 180(1):163-70. Hallett WH, Ames E, Motarjemi M, Barao I, Shanker A, Tamang DL, Sayers TJ, Hudig D, Murphy WJ. PMID: 18097016.
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    151. Initial sequence and comparative analysis of the cat genome. Genome Res. 2007 Nov; 17(11):1675-89. Pontius JU, Mullikin JC, Smith DR, Lindblad-Toh K, Gnerre S, Clamp M, Chang J, Stephens R, Neelam B, Volfovsky N, Schäffer AA, Agarwala R, Narfström K, Murphy WJ, Giger U, Roca AL, Antunes A, Menotti-Raymond M, Yuhki N, Pecon-Slattery J, Johnson WE, Bourque G, Tesler G, O'Brien SJ. PMID: 17975172.
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    152. Gene conversion between mammalian CCR2 and CCR5 chemokine receptor genes: a potential mechanism for receptor dimerization. Genomics. 2007 Aug; 90(2):213-24. Vàzquez-Salat N, Yuhki N, Beck T, O'Brien SJ, Murphy WJ. PMID: 17544254.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    153. Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells. J Immunol. 2007 May 01; 178(9):5753-61. Zhou Q, Gault RA, Kozel TR, Murphy WJ. PMID: 17442959.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    154. IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy. Nat Med. 2007 Mar; 13(3):354-60. Berner V, Liu H, Zhou Q, Alderson KL, Sun K, Weiss JM, Back TC, Longo DL, Blazar BR, Wiltrout RH, Welniak LA, Redelman D, Murphy WJ. PMID: 17334371.
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    155. Use of systemic proteasome inhibition as an immune-modulating agent in disease. Endocr Metab Immune Disord Drug Targets. 2007 Mar; 7(1):29-34. Mattingly LH, Gault RA, Murphy WJ. PMID: 17346202.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    156. The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality. Biol Blood Marrow Transplant. 2007 May; 13(5):521-9. Sun K, Li M, Konopleva M, Konoplev S, Stephens LC, Kornblau SM, Frolova O, Wilkins DE, Ma W, Welniak LA, Andreeff M, Murphy WJ. PMID: 17448911.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    157. Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol. 2007; 25:139-70. Welniak LA, Blazar BR, Murphy WJ. PMID: 17129175.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimals
    158. [Relationship between CCR5 and acute graft-versus-host disease in murine bone marrow transplantation]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2006 Oct; 14(5):934-40. Wang Z, Murphy WJ. PMID: 17096892.
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    159. A 1.5-Mb-resolution radiation hybrid map of the cat genome and comparative analysis with the canine and human genomes. Genomics. 2007 Feb; 89(2):189-96. Murphy WJ, Davis B, David VA, Agarwala R, Schäffer AA, Pearks Wilkerson AJ, Neelam B, O'Brien SJ, Menotti-Raymond M. PMID: 16997530.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    160. Positive and negative regulation of Natural Killer cells: therapeutic implications. Semin Cancer Biol. 2006 Oct; 16(5):367-82. Hallett WH, Murphy WJ. PMID: 16934486.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    161. Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression. J Immunol. 2006 Jun 01; 176(11):6543-52. Shorts L, Weiss JM, Lee JK, Welniak LA, Subleski J, Back T, Murphy WJ, Wiltrout RH. PMID: 16709811.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    162. Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis. Infect Immun. 2006 Apr; 74(4):2161-8. Zhou Q, Gault RA, Kozel TR, Murphy WJ. PMID: 16552046.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    163. Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells. Proc Natl Acad Sci U S A. 2006 Apr 04; 103(14):5460-5. Barao I, Hanash AM, Hallett W, Welniak LA, Sun K, Redelman D, Blazar BR, Levy RB, Murphy WJ. PMID: 16567639.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    164. The late Miocene radiation of modern Felidae: a genetic assessment. Science. 2006 Jan 06; 311(5757):73-7. Johnson WE, Eizirik E, Pecon-Slattery J, Murphy WJ, Antunes A, Teeling E, O'Brien SJ. PMID: 16400146.
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    165. Immune response and immunotherapy to Cryptococcus infections. Immunol Res. 2006; 35(3):191-208. Zhou Q, Murphy WJ. PMID: 17172646.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    166. The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis. Ann N Y Acad Sci. 2005 Nov; 1059:160-7. Brooks AD, Ramirez T, Toh U, Onksen J, Elliott PJ, Murphy WJ, Sayers TJ. PMID: 16382051.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    167. Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy. Cancer Immunol Immunother. 2006 Jan; 55(1):76-84. Sayers TJ, Murphy WJ. PMID: 15864587.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    168. Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L. Cell Immunol. 2005 Jun; 235(2):145-52. Lee JK, Seki N, Sayers TJ, Subleski J, Gruys EM, Murphy WJ, Wiltrout RH. PMID: 16213477.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    169. A rhesus macaque radiation hybrid map and comparative analysis with the human genome. Genomics. 2005 Oct; 86(4):383-95. Murphy WJ, Agarwala R, Schäffer AA, Stephens R, Smith C, Crumpler NJ, David VA, O'Brien SJ. PMID: 16039092.
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    170. Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD). Philos Trans R Soc Lond B Biol Sci. 2005 Sep 29; 360(1461):1747-67. Blazar BR, Murphy WJ. PMID: 16147539.
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    171. Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation. Blood. 2006 Jan 01; 107(1):410-2. Welniak LA, Kuprash DV, Tumanov AV, Panoskaltsis-Mortari A, Blazar BR, Sun K, Nedospasov SA, Murphy WJ. PMID: 16160014.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    172. In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells. J Immunol. 2005 Jul 15; 175(2):693-9. Ortaldo JR, Winkler-Pickett RT, Bere EW, Watanabe M, Murphy WJ, Wiltrout RH. PMID: 16002664.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    173. Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood. 2005 Nov 01; 106(9):3293-9. Sun K, Wilkins DE, Anver MR, Sayers TJ, Panoskaltsis-Mortari A, Blazar BR, Welniak LA, Murphy WJ. PMID: 15961519.
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    174. Novel tumor necrosis factor-knockout mice that lack Peyer's patches. Eur J Immunol. 2005 May; 35(5):1592-600. Kuprash DV, Tumanov AV, Liepinsh DJ, Koroleva EP, Drutskaya MS, Kruglov AA, Shakhov AN, Southon E, Murphy WJ, Tessarollo L, Grivennikov SI, Nedospasov SA. PMID: 15832287.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    175. Insertional polymorphisms of endogenous feline leukemia viruses. J Virol. 2005 Apr; 79(7):3979-86. Roca AL, Nash WG, Menninger JC, Murphy WJ, O'Brien SJ. PMID: 15767400.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    176. Lack of correlation between an assay used to determine early marrow allograft rejection and long-term chimerism after murine allogeneic bone marrow transplantation: effects of marrow dose. Biol Blood Marrow Transplant. 2005 Apr; 11(4):252-9. Koh CY, Welniak LA, Murphy WJ. PMID: 15812390.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    177. Serum-dependent potentiation of lipopolysaccharide-induced nitric oxide production is mediated by the events after the transcription of inducible type of nitric oxide synthase. Cell Immunol. 2005 Mar; 234(1):16-22. Zhang YH, Murphy WJ, Russell SW, Morrison DC, Koide N, Yoshida T, Yokochi T. PMID: 15936007.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    178. A molecular phylogeny for bats illuminates biogeography and the fossil record. Science. 2005 Jan 28; 307(5709):580-4. Teeling EC, Springer MS, Madsen O, Bates P, O'brien SJ, Murphy WJ. PMID: 15681385.
      View in: PubMed   Mentions: 231     Fields:    Translation:Animals
    179. The feline major histocompatibility complex is rearranged by an inversion with a breakpoint in the distal class I region. Immunogenetics. 2005 Jan; 56(10):702-9. Beck TW, Menninger J, Murphy WJ, Nash WG, O'brien SJ, Yuhki N. PMID: 15592824.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    180. Mammalian phylogenomics comes of age. Trends Genet. 2004 Dec; 20(12):631-9. Murphy WJ, Pevzner PA, O'Brien SJ. PMID: 15522459.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimals
    181. Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration. Blood. 2005 Jan 01; 105(1):428-31. Gendelman M, Halligan N, Komorowski R, Logan B, Murphy WJ, Blazar BR, Pritchard KA, Drobyski WR. PMID: 15331451.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    182. Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects. Biol Blood Marrow Transplant. 2004 Aug; 10(8):534-9. Welniak LA, Shorts L, Subleski J, Blazar BR, Wiltrout RH, Murphy WJ. PMID: 15282531.
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    183. Mesozoic origin for West Indian insectivores. Nature. 2004 Jun 10; 429(6992):649-51. Roca AL, Bar-Gal GK, Eizirik E, Helgen KM, Maria R, Springer MS, O'Brien SJ, Murphy WJ. PMID: 15190349.
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    184. Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib. Proc Natl Acad Sci U S A. 2004 May 25; 101(21):8120-5. Sun K, Welniak LA, Panoskaltsis-Mortari A, O'Shaughnessy MJ, Liu H, Barao I, Riordan W, Sitcheran R, Wysocki C, Serody JS, Blazar BR, Sayers TJ, Murphy WJ. PMID: 15148407.
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    185. mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):5042-7. Kozel TR, Murphy WJ, Brandt S, Blazar BR, Lovchik JA, Thorkildson P, Percival A, Lyons CR. PMID: 15051894.
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    186. An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease. Exp Hematol. 2004 Mar; 32(3):318-24. Welniak LA, Wang Z, Sun K, Kuziel W, Anver MR, Blazar BR, Murphy WJ. PMID: 15003318.
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    187. Natural killer cells: biology and clinical use in cancer therapy. Cell Mol Immunol. 2004 Feb; 1(1):12-21. Hallett WH, Murphy WJ. PMID: 16212916.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    188. Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides. J Immunol. 2004 Jan 15; 172(2):943-53. Ortaldo JR, Young HA, Winkler-Pickett RT, Bere EW, Murphy WJ, Wiltrout RH. PMID: 14707067.
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    189. Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis. Biol Blood Marrow Transplant. 2004 Jan; 10(1):32-9. Welniak LA, Karas M, Yakar S, Anver MR, Murphy WJ, LeRoith D. PMID: 14752777.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    190. The immunobiology of natural killer cells and bone marrow allograft rejection. Biol Blood Marrow Transplant. 2003 Dec; 9(12):727-41. Barao I, Murphy WJ. PMID: 14677112.
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    191. Reconstructing the genomic architecture of mammalian ancestors using multispecies comparative maps. Hum Genomics. 2003 Nov; 1(1):30-40. Murphy WJ, Bourque G, Tesler G, Pevzner P, O'Brien SJ. PMID: 15601531.
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    192. Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration. Clin Immunol. 2003 Nov; 109(2):197-202. Dorshkind K, Welniak L, Gault RA, Hixon J, Montecino-Rodriguez E, Horseman ND, Gertner JM, Murphy WJ. PMID: 14597218.
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    193. Genomics. A dog's breakfast? Science. 2003 Sep 26; 301(5641):1854-5. O'Brien SJ, Murphy WJ. PMID: 14512608.
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    194. Nuclear gene sequences confirm an ancient link between New Zealand's short-tailed bat and South American noctilionoid bats. Mol Phylogenet Evol. 2003 Aug; 28(2):308-19. Teeling EC, Madsen O, Murphy WJ, Springer MS, O'Brien SJ. PMID: 12878467.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    195. NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade. Blood. 2003 Dec 01; 102(12):4067-75. Koh CY, Ortaldo JR, Blazar BR, Bennett M, Murphy WJ. PMID: 12893752.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    196. The origin of human chromosome 1 and its homologs in placental mammals. Genome Res. 2003 Aug; 13(8):1880-8. Murphy WJ, Frönicke L, O'Brien SJ, Stanyon R. PMID: 12869576.
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    197. Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice. Biol Blood Marrow Transplant. 2003 Jul; 9(7):426-34. Sun R, Gault RA, Welniak LA, Tian ZG, Richards S, Murphy WJ. PMID: 12869956.
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    198. Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood. 2003 Sep 15; 102(6):1966-77. Salcedo R, Zhang X, Young HA, Michael N, Wasserman K, Ma WH, Martins-Green M, Murphy WJ, Oppenheim JJ. PMID: 12791666.
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    199. The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood. 2003 Jul 01; 102(1):303-10. Sayers TJ, Brooks AD, Koh CY, Ma W, Seki N, Raziuddin A, Blazar BR, Zhang X, Elliott PJ, Murphy WJ. PMID: 12637321.
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    200. Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses. J Immunol. 2003 Mar 01; 170(5):2727-33. Murphy WJ, Welniak L, Back T, Hixon J, Subleski J, Seki N, Wigginton JM, Wilson SE, Blazar BR, Malyguine AM, Sayers TJ, Wiltrout RH. PMID: 12594303.
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    201. IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function. Blood. 2003 Jun 15; 101(12):5076-83. Chen ZM, O'Shaughnessy MJ, Gramaglia I, Panoskaltsis-Mortari A, Murphy WJ, Narula S, Roncarolo MG, Blazar BR. PMID: 12609834.
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    202. Chapter 5 Growth hormone. . 2003 Jan 1; I(Cell741993):103-113. Lisbeth A. Welniak, William J. Murphy. .
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    203. Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens. Blood. 2002 Oct 15; 100(8):3026-33. Raziuddin A, Longo DL, Bennett M, Winkler-Pickett R, Ortaldo JR, Murphy WJ. PMID: 12351417.
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    204. Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma xenografts. Clin Cancer Res. 2002 Aug; 8(8):2655-65. Salcedo R, Martins-Green M, Gertz B, Oppenheim JJ, Murphy WJ. PMID: 12171898.
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    205. Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax. Blood. 2002 Jul 01; 100(1):217-23. Szocinski JL, Khaled AR, Hixon J, Halverson D, Funakoshi S, Fanslow WC, Boyd A, Taub DD, Durum SK, Siegall CB, Longo DL, Murphy WJ. PMID: 12070030.
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    206. The Feline Genome Project. Annu Rev Genet. 2002; 36:657-86. O'Brien SJ, Menotti-Raymond M, Murphy WJ, Yuhki N. PMID: 12359739.
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    207. Susceptibility to the ototoxic properties of toluene is species specific. Hear Res. 2002 Apr; 166(1-2):24-32. Davis RR, Murphy WJ, Snawder JE, Striley CA, Henderson D, Khan A, Krieg EF. PMID: 12062755.
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    208. Low responsiveness to IFN-gamma, after pretreatment of mouse macrophages with lipopolysaccharides, develops via diverse regulatory pathways. Eur J Immunol. 2002 03; 32(3):710-9. Crespo A, Filla MB, Murphy WJ. PMID: 11870615.
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    209. The role of growth hormone in T-cell development and reconstitution. J Leukoc Biol. 2002 Mar; 71(3):381-7. Welniak LA, Sun R, Murphy WJ. PMID: 11867675.
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    210. Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer. Stem Cells. 2002; 20(6):573-82. Kadereit S, Deeds LS, Haynesworth SE, Koc ON, Kozik MM, Szekely E, Daum-Woods K, Goetchius GW, Fu P, Welniak LA, Murphy WJ, Laughlin MJ. PMID: 12456965.
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    211. Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells. J Immunol. 2002 Jan 01; 168(1):434-42. Cui YH, Le Y, Gong W, Proost P, Van Damme J, Murphy WJ, Wang JM. PMID: 11751990.
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    212. NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution. Biol Blood Marrow Transplant. 2002; 8(1):17-25. Koh CY, Raziuddin A, Welniak LA, Blazar BR, Bennett M, Murphy WJ. PMID: 11846352.
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    213. Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut. Biol Blood Marrow Transplant. 2002; 8(6):316-25. Hixon JA, Anver MR, Blazar BR, Panoskaltsis-Mortari A, Wiltrout RH, Murphy WJ. PMID: 12108917.
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    214. Potential applications of growth hormone in promoting immune reconstitution. . 2002 Jan 1; 2:101-110. Lisbeth Welniak, Rui Sun, William J. Murphy. .
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    215. The diverse role of chemokines in tumor progression: prospects for intervention (Review). Int J Mol Med. 2001 Sep; 8(3):235-44. Schneider GP, Salcedo R, Welniak LA, Howard OM, Murphy WJ. PMID: 11494048.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    216. Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells. J Immunol. 2001 Jun 15; 166(12):7571-8. Salcedo R, Young HA, Ponce ML, Ward JM, Kleinman HK, Murphy WJ, Oppenheim JJ. PMID: 11390513.
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    217. Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies. Immunol Rev. 2001 Jun; 181:279-89. Murphy WJ, Koh CY, Raziuddin A, Bennett M, Longo DL. PMID: 11513149.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    218. Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo. Blood. 2001 May 15; 97(10):3132-7. Koh CY, Blazar BR, George T, Welniak LA, Capitini CM, Raziuddin A, Murphy WJ, Bennett M. PMID: 11342440.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    219. The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice. Biochem Biophys Res Commun. 2001 Apr 13; 282(4):971-6. Tani K, Murphy WJ, Chertov O, Oppenheim JJ, Wang JM. PMID: 11352647.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    220. Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation. J Immunol. 2001 Mar 01; 166(5):2924-8. Welniak LA, Khaled AR, Anver MR, Komschlies KL, Wiltrout RH, Durum S, Ruscetti FR, Blazar BR, Murphy WJ. PMID: 11207240.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    221. Thymic emigrants isolated by a new method possess unique phenotypic and functional properties. Blood. 2001 Mar 01; 97(5):1360-9. Lee CK, Kim K, Welniak LA, Murphy WJ, Muegge K, Durum SK. PMID: 11222381.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    222. Role of interleukin-12 in acute graft-versus-host disease(1). Transplant Proc. 2001 Feb-Mar; 33(1-2):1752-3. Welniak LA, Blazar BR, Wiltrout RH, Anver MR, Murphy WJ. PMID: 11267498.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    223. Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease. Blood. 2001 Jan 15; 97(2):565-71. Boussiotis VA, Chen ZM, Zeller JC, Murphy WJ, Berezovskaya A, Narula S, Roncarolo MG, Blazar BR. PMID: 11154238.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    224. Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2001; 7(3):136-43. Hixon JA, Blazar BR, Anver MR, Wiltrout RH, Murphy WJ. PMID: 11302547.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    225. Effects of prolactin on hematopoiesis. Lupus. 2001; 10(10):700-5. Welniak LA, Richards SM, Murphy WJ. PMID: 11721696.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    226. Alternative strategies other than growth hormone for the treatment of immune diseases. Trends Immunol. 2001 Jan; 22(1):14-6. Famularo G, Di Marzio L, Ulisse S, Cifone MG, De Simone C. PMID: 11334029.
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    227. Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury. Blood. 2000 Dec 15; 96(13):4350-6. Panoskaltsis-Mortari A, Taylor PA, Rubin JS, Uren A, Welniak LA, Murphy WJ, Farrell CL, Lacey DL, Blazar BR. PMID: 11110712.
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    228. Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions. J Immunol. 2000 Nov 01; 165(9):4901-9. Blazar BR, Lees CJ, Martin PJ, Noelle RJ, Kwon B, Murphy W, Taylor PA. PMID: 11046015.
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    229. Adoptive cellular immunotherapy: NK cells and bone marrow transplantation. Histol Histopathol. 2000 10; 15(4):1201-10. Koh CY, Welniak LA, Murphy WJ. PMID: 11005245.
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    230. Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes. J Clin Invest. 2000 Sep; 106(6):745-7. Murphy WJ. PMID: 10995784.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    231. Use of human prolactin as a therapeutic protein to potentiate immunohematopoietic function. J Neuroimmunol. 2000 Sep 01; 109(1):56-62. Richards SM, Murphy WJ. PMID: 10969182.
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    232. Effects of growth hormone and prolactin on hematopoiesis. Leuk Lymphoma. 2000 Aug; 38(5-6):435-45. Welniak LA, Tian ZG, Sun R, Keller JR, Richards S, Ruscetti FW, Murphy WJ. PMID: 10953965.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    233. Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation. Blood. 2000 Aug 01; 96(3):834-9. Panoskaltsis-Mortari A, Strieter RM, Hermanson JR, Fegeding KV, Murphy WJ, Farrell CL, Lacey DL, Blazar BR. PMID: 10910893.
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    234. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood. 2000 Jul 01; 96(1):34-40. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK, Oppenheim JJ, Murphy WJ. PMID: 10891427.
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    235. Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts. Blood. 2000 Jun 15; 95(12):3840-4. Raziuddin A, Bennett M, Winkler-Pickett R, Ortaldo JR, Longo DL, Murphy WJ. PMID: 10845918.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    236. Role for CD40-CD40 ligand interactions in the immune response to solid tumours. Mol Immunol. 2000 Jun; 37(9):515-26. Alexandroff AB, Jackson AM, Paterson T, Haley JL, Ross JA, Longo DL, Murphy WJ, James K, Taub DD. PMID: 11163401.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    237. Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens. Int Immunol. 2000 May; 12(5):691-700. Tani K, Murphy WJ, Chertov O, Salcedo R, Koh CY, Utsunomiya I, Funakoshi S, Asai O, Herrmann SH, Wang JM, Kwak LW, Oppenheim JJ. PMID: 10784615.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    238. Growth hormone as an immunomodulating therapeutic agent. Immunol Today. 2000 May; 21(5):211-3. Murphy WJ, Longo DL. PMID: 10877541.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    239. Inhibition of MDA-MB-231 human breast tumor xenografts and HER2 expression by anti-tumor agents GAP31 and MAP30. Anticancer Res. 2000 Mar-Apr; 20(2A):653-9. Lee-Huang S, Huang PL, Sun Y, Chen HC, Kung HF, Huang PL, Murphy WJ. PMID: 10810336.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    240. Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning. Biol Blood Marrow Transplant. 2000; 6(6):604-12. Welniak LA, Blazar BR, Anver MR, Wiltrout RH, Murphy WJ. PMID: 11128810.
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    241. Differential effects of CD40 stimulation on normal and neoplastic cell growth. Arch Immunol Ther Exp (Warsz). 2000; 48(4):225-33. Ziebold JL, Hixon J, Boyd A, Murphy WJ. PMID: 11059638.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    242. New strategies for preventing graft-versus-host disease. Curr Opin Immunol. 1999 Oct; 11(5):509-15. Murphy WJ, Blazar BR. PMID: 10508701.
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    243. Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta. J Immunol. 1999 Oct 01; 163(7):3684-91. Zeller JC, Panoskaltsis-Mortari A, Murphy WJ, Ruscetti FW, Narula S, Roncarolo MG, Blazar BR. PMID: 10490963.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    244. Ly-49 receptor expression and functional analysis in multiple mouse strains. J Leukoc Biol. 1999 Sep; 66(3):512-20. Ortaldo JR, Mason AT, Winkler-Pickett R, Raziuddin A, Murphy WJ, Mason LH. PMID: 10496323.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    245. Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells. J Leukoc Biol. 1999 Jun; 65(6):891-9. Kirken RA, Erwin RA, Taub D, Murphy WJ, Behbod F, Wang L, Pericle F, Farrar WL. PMID: 10380915.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    246. Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine. Exp Hematol. 1999 May; 27(5):811-6. Woody MA, Welniak LA, Sun R, Tian ZG, Henry M, Richards S, Raziuddin A, Longo DL, Murphy WJ. PMID: 10340396.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    247. Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand. Blood. 1999 May 01; 93(9):2999-3007. Hirano A, Longo DL, Taub DD, Ferris DK, Young LS, Eliopoulos AG, Agathanggelou A, Cullen N, Macartney J, Fanslow WC, Murphy WJ. PMID: 10216096.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    248. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha. Am J Pathol. 1999 Apr; 154(4):1125-35. Salcedo R, Wasserman K, Young HA, Grimm MC, Howard OM, Anver MR, Kleinman HK, Murphy WJ, Oppenheim JJ. PMID: 10233851.
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    249. Cloning thymic precursor cells: demonstration that individual pro-T1 cells have dual T-NK potential and individual pro-T2 cells have dual alphabeta-gammadelta T cell potential. Cell Immunol. 1999 Feb 01; 191(2):139-44. Lee CK, Kim K, Geiman TM, Murphy WJ, Muegge K, Durum SK. PMID: 9973536.
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    250. Generation of artificial proteoglycans containing glycosaminoglycan-modified CD44. Demonstration of the interaction between rantes and chondroitin sulfate. J Biol Chem. 1999 Jan 22; 274(4):2518-24. Wolff EA, Greenfield B, Taub DD, Murphy WJ, Bennett KL, Aruffo A. PMID: 9891023.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    251. CD40 stimulation promotes human secondary immunoglobulin responses in HuPBL-SCID chimeras. Clin Immunol. 1999 Jan; 90(1):22-7. Murphy WJ, Funakoshi S, Fanslow WC, Rager HC, Taub DD, Longo DL. PMID: 9884349.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    252. Use of neuroendocrine hormones to promote reconstitution after bone marrow transplantation. Neuroimmunomodulation. 1999 Jan-Apr; 6(1-2):69-80. Woody MA, Welniak LA, Richards S, Taub DD, Tian Z, Sun R, Longo DL, Murphy WJ. PMID: 9876237.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    253. Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest. 1998 Nov 01; 102(9):1742-8. Murphy WJ, Welniak LA, Taub DD, Wiltrout RH, Taylor PA, Vallera DA, Kopf M, Young H, Longo DL, Blazar BR. PMID: 9802888.
      View in: PubMed   Mentions: 70     Fields:    Translation:Animals
    254. CD16 cross-linking blocks rearrangement of the TCR beta locus and development of alpha beta T cells and induces development of NK cells from thymic progenitors. J Immunol. 1998 Oct 01; 161(7):3325-9. Durum SK, Lee CK, Geiman TM, Murphy WJ, Muegge K. PMID: 9759848.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    255. Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice. Exp Hematol. 1998 Jun; 26(6):507-14. Spence SE, Keller JR, Ruscetti FW, McCauslin CS, Gooya JM, Funakoshi S, Longo DL, Murphy WJ. PMID: 9620284.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    256. Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients. AIDS. 1998 May 28; 12(8):895-904. Nguyen BY, Clerici M, Venzon DJ, Bauza S, Murphy WJ, Longo DL, Baseler M, Gesundheit N, Broder S, Shearer G, Yarchoan R. PMID: 9631143.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsCTClinical Trials
    257. In vivo alloreactive potential of ex vivo-expanded primary T lymphocytes. Transplantation. 1998 May 27; 65(10):1365-70. Contassot E, Murphy W, Angonin R, Pavy JJ, Bittencourt MC, Robinet E, Reynolds CW, Cahn JY, Hervé P, Tiberghien P. PMID: 9625020.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    258. Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation. J Clin Invest. 1998 May 01; 101(9):1835-42. Asai O, Longo DL, Tian ZG, Hornung RL, Taub DD, Ruscetti FW, Murphy WJ. PMID: 9576746.
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    259. Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice. Stem Cells. 1998; 16(3):193-9. Tian ZG, Woody MA, Sun R, Welniak LA, Raziuddin A, Funakoshi S, Tsarfaty G, Longo DL, Murphy WJ. PMID: 9617894.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    260. Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets. J Immunol. 1998 Jan 01; 160(1):87-94. Raziuddin A, Longo DL, Mason L, Ortaldo JR, Bennett M, Murphy WJ. PMID: 9551959.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    261. Prospects for cytokine and chemokine biotherapy. Clin Cancer Res. 1997 Dec; 3(12 Pt 2):2682-6. Oppenheim JJ, Murphy WJ, Chertox O, Schirrmacher V, Wang JM. PMID: 10068274.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    262. Antitumor effects of nonconjugated murine Lym-2 and human-mouse chimeric CLL-1 monoclonal antibodies against various human lymphoma cell lines in vitro and in vivo. Blood. 1997 Oct 15; 90(8):3160-6. Funakoshi S, Hirano A, Beckwith M, Asai O, Jorgensen G, Tian Z, Hornick JL, Hu P, Khawli LA, Epstein AL, Longo DL, Murphy WJ. PMID: 9376598.
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    263. Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils. J Exp Med. 1997 Aug 29; 186(5):739-47. Chertov O, Ueda H, Xu LL, Tani K, Murphy WJ, Wang JM, Howard OM, Sayers TJ, Oppenheim JJ. PMID: 9271589.
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    264. The potential role of NK cells in the separation of graft-versus-tumor effects from graft-versus-host disease after allogeneic bone marrow transplantation. Immunol Rev. 1997 Jun; 157:167-76. Murphy WJ, Longo DL. PMID: 9255629.
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    265. Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin. J Immunol. 1997 Mar 15; 158(6):2745-55. Taub DD, Murphy WJ, Asai O, Fenton RG, Peltz G, Key ML, Turcovski-Corrales S, Longo DL. PMID: 9058809.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    266. Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice. J Clin Invest. 1997 Feb 01; 99(3):484-91. Funakoshi S, Taub DD, Anver MR, Raziuddin A, Asai O, Reddy V, Rager H, Fanslow WC, Longo DL, Murphy WJ. PMID: 9022082.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    267. Effects of CD40 stimulation in the prevention of human EBV-lymphomagenesis. Leuk Lymphoma. 1997 Jan; 24(3-4):187-99. Funakoshi S, Taub DD, Asai O, Hirano A, Ruscetti FW, Longo DL, Murphy WJ. PMID: 9156649.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    268. Chemokine-induced human lymphocyte infiltration and engraftment in huPBL-SCID mice. Methods Enzymol. 1997; 287:265-91. Taub DD, Key ML, Longo DL, Murphy WJ. PMID: 9330328.
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    269. Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice. Int Immunol. 1996 Dec; 8(12):1833-9. Raziuddin A, Longo DL, Mason L, Ortaldo JR, Murphy WJ. PMID: 8982767.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    270. Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T-cell infiltration into human melanoma xenografts. J Immunother Emphasis Tumor Immunol. 1996 Sep; 19(5):317-23. Conlon KC, Anver MR, Longo DL, Ortaldo JR, Murphy WJ. PMID: 8941871.
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    271. The huPBL-SCID mouse as a means to examine human immune function in vivo. Semin Immunol. 1996 Aug; 8(4):233-41. Murphy WJ, Taub DD, Longo DL. PMID: 8883146.
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    272. IL-8-Induced T-Lymphocyte Migration: Direct as Well as Indirect Mechanisms Methods. 1996 Aug; 10(1):135-44. Wang JM, Xu L, Murphy WJ, Taub DD, Chertov O. PMID: 8812653.
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    273. T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest. 1996 Apr 15; 97(8):1931-41. Taub DD, Anver M, Oppenheim JJ, Longo DL, Murphy WJ. PMID: 8621778.
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    274. Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection. Blood. 1996 Apr 01; 87(7):2723-31. Schwarzenberger P, Spence S, Lohrey N, Kmiecik T, Longo DL, Murphy WJ, Ruscetti FW, Keller JR. PMID: 8639888.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    275. NK Cells in the Regulation of Hematopoiesis Methods. 1996 Apr; 9(2):344-51. Murphy WJ, Longo DL. PMID: 8812687.
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    276. Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro. J Immunol. 1996 Mar 15; 156(6):2095-2103. Taub DD, Turcovski-Corrales SM, Key ML, Longo DL, Murphy WJ. PMID: 8690897.
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    277. Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice. J Immunol. 1996 Mar 15; 156(6):2104-11. Murphy WJ, Tian ZG, Asai O, Funakoshi S, Rotter P, Henry M, Strieter RM, Kunkel SL, Longo DL, Taub DD. PMID: 8690898.
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    278. Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas. J Immunother Emphasis Tumor Immunol. 1996 Mar; 19(2):93-101. Funakoshi S, Longo DL, Murphy WJ. PMID: 8732692.
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    279. Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice. Blood. 1996 Feb 15; 87(4):1423-31. Taub DD, Longo DL, Murphy WJ. PMID: 8608232.
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    280. Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem. 1996 Feb 09; 271(6):2935-40. Chertov O, Michiel DF, Xu L, Wang JM, Tani K, Murphy WJ, Longo DL, Taub DD, Oppenheim JJ. PMID: 8621683.
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    281. Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production. J Leukoc Biol. 1996 Jan; 59(1):81-9. Taub DD, Ortaldo JR, Turcovski-Corrales SM, Key ML, Longo DL, Murphy WJ. PMID: 8558072.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    282. In vivo antitumor effects of unconjugated CD30 monoclonal antibodies on human anaplastic large-cell lymphoma xenografts. Cancer Res. 1995 Nov 15; 55(22):5335-41. Tian ZG, Longo DL, Funakoshi S, Asai O, Ferris DK, Widmer M, Murphy WJ. PMID: 7585597.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    283. Engraftment of SCID mice by human bone marrow hematopoietic cells cultured in vitro: an in vivo model for human gene transfer. Leukemia. 1995 Oct; 9 Suppl 1:S43-7. Spence SE, Keller JR, Ruscetti FW, Czarra KT, Gooya JM, Funakoshi S, Longo DL, Murphy WJ. PMID: 7475312.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    284. NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice. J Immunol. 1995 Sep 15; 155(6):2911-7. Murphy WJ, Raziuddin A, Mason L, Kumar V, Bennett M, Longo DL. PMID: 7673708.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    285. Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocytes. Blood. 1995 Sep 01; 86(5):1946-53. Murphy WJ, Funakoshi S, Beckwith M, Rushing SE, Conley DK, Armitage RJ, Fanslow WC, Rager HC, Taub DD, Ruscetti FW. PMID: 7544649.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    286. A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion. J Immunol. 1995 Aug 01; 155(3):1184-90. Xu L, Badolato R, Murphy WJ, Longo DL, Anver M, Hale S, Oppenheim JJ, Wang JM. PMID: 7636186.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    287. Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta. Cell Growth Differ. 1995 Jun; 6(6):655-63. Turley JM, Funakoshi S, Ruscetti FW, Kasper J, Murphy WJ, Longo DL, Birchenall-Roberts MC. PMID: 7669719.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    288. Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes. J Clin Invest. 1995 Mar; 95(3):1370-6. Taub DD, Proost P, Murphy WJ, Anver M, Longo DL, van Damme J, Oppenheim JJ. PMID: 7883984.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    289. Cellular and molecular studies in the treatment of murine renal cancer. Semin Oncol. 1995 Feb; 22(1):9-16. Wiltrout RH, Gregorio TA, Fenton RG, Longo DL, Ghosh P, Murphy WJ, Komschlies KL. PMID: 7855624.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    290. Epstein-Barr virus-induced human B-cell lymphoma arising in HuPBL-SCID chimeric mice: characterization and the role of CD40 stimulation in their treatment and prevention. Pathobiology. 1995; 63(3):133-42. Funakoshi S, Beckwith M, Fanslow W, Longo DL, Murphy WJ. PMID: 8821629.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    291. Effects of growth hormone and prolactin immune development and function. Life Sci. 1995; 57(1):1-14. Murphy WJ, Rui H, Longo DL. PMID: 7596216.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    292. Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration. Exp Hematol. 1994 Dec; 22(13):1273-7. Tsarfaty G, Longo DL, Murphy WJ. PMID: 7957713.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    293. Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation? Blood. 1994 Aug 15; 84(4):1333-41. Tiberghien P, Reynolds CW, Keller J, Spence S, Deschaseaux M, Certoux JM, Contassot E, Murphy WJ, Lyons R, Chiang Y. PMID: 8049449.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    294. Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID). J Immunol. 1994 Aug 01; 153(3):1004-14. Murphy WJ, Durum SK, Anver MR, Ferris DK, McVicar DW, O'Shea JJ, Ruscetti SK, Smith MR, Young HA, Longo DL. PMID: 7913108.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    295. Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency. Eur J Immunol. 1994 Aug; 24(8):1823-7. Murphy WJ, Taub DD, Anver M, Conlon K, Oppenheim JJ, Kelvin DJ, Longo DL. PMID: 7519996.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    296. Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J Exp Med. 1994 Jul 01; 180(1):203-9. Badolato R, Wang JM, Murphy WJ, Lloyd AR, Michiel DF, Bausserman LL, Kelvin DJ, Oppenheim JJ. PMID: 7516407.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    297. Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment. J Clin Invest. 1994 Jul; 94(1):293-300. Taub DD, Tsarfaty G, Lloyd AR, Durum SK, Longo DL, Murphy WJ. PMID: 7518833.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    298. Inhibition of human B-cell lymphoma growth by CD40 stimulation. Blood. 1994 May 15; 83(10):2787-94. Funakoshi S, Longo DL, Beckwith M, Conley DK, Tsarfaty G, Tsarfaty I, Armitage RJ, Fanslow WC, Spriggs MK, Murphy WJ. PMID: 7514045.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    299. Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice. Blood. 1993 Oct 15; 82(8):2577-84. Siefer AK, Longo DL, Harrison CL, Reynolds CW, Murphy WJ. PMID: 8400305.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    300. Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts. J Clin Invest. 1993 Oct; 92(4):1918-24. Murphy WJ, Back TC, Conlon KC, Komschlies KL, Ortaldo JR, Sayers TJ, Wiltrout RH, Longo DL. PMID: 8408644.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    301. Natural killer cells and bone marrow transplantation. J Natl Cancer Inst. 1993 Sep 15; 85(18):1475-82. Murphy WJ, Reynolds CW, Tiberghien P, Longo DL. PMID: 8360930.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    302. Differential effects of growth hormone and prolactin on murine T cell development and function. J Exp Med. 1993 Jul 01; 178(1):231-6. Murphy WJ, Durum SK, Longo DL. PMID: 8315380.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    303. Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency. J Immunol. 1993 Apr 15; 150(8 Pt 1):3634-42. Murphy WJ, Conlon KC, Sayers TJ, Wiltrout RH, Back TC, Ortaldo JR, Longo DL. PMID: 8468492.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    304. Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo. J Immunol. 1992 Dec 15; 149(12):3851-7. Murphy WJ, Durum SK, Longo DL. PMID: 1460277.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    305. Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma. Brain Behav Immun. 1992 Dec; 6(4):355-64. Murphy WJ, Durum SK, Anver M, Frazier M, Longo DL. PMID: 1336993.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    306. Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine. Blood. 1992 Sep 15; 80(6):1443-7. Murphy WJ, Tsarfaty G, Longo DL. PMID: 1520871.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    307. Hematopoietic growth-promoting effects of natural killer cells in mice in response to in vivo administration of human interleukin-2. J Natl Cancer Inst. 1992 Aug 05; 84(15):1195-200. Murphy WJ, Longo DL. PMID: 1635088.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    308. Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo. Blood. 1992 Aug 01; 80(3):670-7. Murphy WJ, Keller JR, Harrison CL, Young HA, Longo DL. PMID: 1379086.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    309. Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice. J Immunol. 1992 Jun 15; 148(12):3799-805. Murphy WJ, Durum SK, Anver MR, Longo DL. PMID: 1602129.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    310. Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions. Eur J Immunol. 1992 Jun; 22(6):1421-7. Murphy WJ, Bennett M, Anver MR, Baseler M, Longo DL. PMID: 1534757.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    311. Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4481-5. Murphy WJ, Durum SK, Longo DL. PMID: 1584780.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    312. Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation. J Immunol. 1992 May 01; 148(9):2953-60. Murphy WJ, Bennett M, Kumar V, Longo DL. PMID: 1573278.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    313. Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans. Infect Immun. 1991 Sep; 59(9):3101-10. Kozel TR, Wilson MA, Murphy JW. PMID: 1831795.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    314. Natural killer cells activated with interleukin 2 in vitro can be adoptively transferred and mediate hematopoietic histocompatibility-1 antigen-specific bone marrow rejection in vivo. Eur J Immunol. 1990 Aug; 20(8):1729-34. Murphy WJ, Kumar V, Bennett M. PMID: 2209686.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    315. An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells. J Immunol. 1990 May 01; 144(9):3305-11. Murphy WJ, Kumar V, Cope JC, Bennett M. PMID: 2329274.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    316. Immunobiology of bone marrow transplantation: studies using scid mice. Curr Top Microbiol Immunol. 1989; 152:251-8. Murphy WJ, Kumar V, Bennett M. PMID: 2805793.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    317. Rejection of bone marrow cells by irradiated mice: NK and T cells recognize different antigens. Transplant Proc. 1987 Dec; 19(6 Suppl 7):5-11. Bennett M, Kumar V, Mikhael A, Murphy WJ, Rembecki RM, Sentman CL, David CS. PMID: 3321646.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    318. Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized. J Exp Med. 1987 Nov 01; 166(5):1499-509. Murphy WJ, Kumar V, Bennett M. PMID: 3316472.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCellsPHPublic Health
    319. Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection. J Exp Med. 1987 Apr 01; 165(4):1212-7. Murphy WJ, Kumar V, Bennett M. PMID: 3549961.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
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