Chengfei Liu

Title(s)Assistant Professor, Urology
SchoolSchool of Medicine
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment. Mol Cancer Ther. 2022 10 07; 21(10):1594-1607. Ning S, Liu C, Lou W, Yang JC, Lombard AP, D'Abronzo LS, Batra N, Yu AM, Leslie AR, Sharifi M, Evans CP, Gao AC. PMID: 35930737; PMCID: PMC9547958.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. The Immunotherapy and Immunosuppressive Signaling in Therapy-Resistant Prostate Cancer. Biomedicines. 2022 Jul 22; 10(8). Xu P, Wasielewski LJ, Yang JC, Cai D, Evans CP, Murphy WJ, Liu C. PMID: 35892678; PMCID: PMC9394279.
      View in: PubMed   Mentions: 7  
    3. Iron intake and multiple health outcomes: Umbrella review. Crit Rev Food Sci Nutr. 2023; 63(16):2910-2927. Huang Y, Cao D, Chen Z, Chen B, Li J, Wang R, Guo J, Dong Q, Liu C, Wei Q, Liu L. PMID: 34583608.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    4. ARVib suppresses growth of advanced prostate cancer via inhibition of androgen receptor signaling. Oncogene. 2021 09; 40(35):5379-5392. Liu C, Armstrong CM, Ning S, Yang JC, Lou W, Lombard AP, Zhao J, Wu CY, Yu A, Evans CP, Tepper CG, Li PK, Gao AC. PMID: 34272475; PMCID: PMC8413131.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    5. Platinum-Containing Supramolecular Drug Self-Delivery Nanomicelles for Efficient Synergistic Combination Chemotherapy. Biomacromolecules. 2021 06 14; 22(6):2382-2392. Liu C, Li M, Li P, Chen W, Li H, Fan L, Tian W. PMID: 33905223.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    6. Phase Ib trial of reformulated niclosamide with abiraterone/prednisone in men with castration-resistant prostate cancer. Sci Rep. 2021 03 18; 11(1):6377. Parikh M, Liu C, Wu CY, Evans CP, Dall'Era M, Robles D, Lara PN, Agarwal N, Gao AC, Pan CX. PMID: 33737681; PMCID: PMC7973745.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    7. Correction to Supramolecular Drug-Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy. ACS Appl Mater Interfaces. 2020 Sep 30; 12(39):44382. Liu C, Li C, Pang C, Li M, Li H, Li P, Fan L, Liu H, Tian W. PMID: 32935967.
      View in: PubMed   Mentions:    Fields:    
    8. Steroid Sulfatase Stimulates Intracrine Androgen Synthesis and is a Therapeutic Target for Advanced Prostate Cancer. Clin Cancer Res. 2020 11 15; 26(22):6064-6074. Armstrong CM, Liu C, Liu L, Yang JC, Lou W, Zhao R, Ning S, Lombard AP, Zhao J, D'Abronzo LS, Evans CP, Li PK, Gao AC. PMID: 32928794; PMCID: PMC7669645.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Supramolecular Drug-Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy. ACS Appl Mater Interfaces. 2020 Jun 24; 12(25):27940-27950. Liu C, Li C, Pang C, Li M, Li H, Li P, Fan L, Liu H, Tian W. PMID: 32449351.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer. Mol Cancer Ther. 2020 08; 19(8):1708-1718. Zhao J, Ning S, Lou W, Yang JC, Armstrong CM, Lombard AP, D'Abronzo LS, Evans CP, Gao AC, Liu C. PMID: 32430485; PMCID: PMC8855880.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    11. Therapeutic Targeting of MDR1 Expression by RORγ Antagonists Resensitizes Cross-Resistant CRPC to Taxane via Coordinated Induction of Cell Death Programs. Mol Cancer Ther. 2020 02; 19(2):364-374. Wang Y, Huang Z, Chen CZ, Liu C, Evans CP, Gao AC, Zhou F, Chen HW. PMID: 31712394.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. Wntless promotes cellular viability and resistance to enzalutamide in castration-resistant prostate cancer cells. Am J Clin Exp Urol. 2019; 7(4):203-214. Lombard AP, Liu C, Armstrong CM, D'Abronzo LS, Lou W, Evans CP, Gao AC. PMID: 31511827; PMCID: PMC6734040.
      View in: PubMed   Mentions: 10  
    13. GnRH Antagonists Have Direct Inhibitory Effects On Castration-Resistant Prostate Cancer Via Intracrine Androgen and AR-V7 Expression. Mol Cancer Ther. 2019 10; 18(10):1811-1821. Cucchiara V, Yang JC, Liu C, Adomat HH, Tomlinson Guns ES, Gleave ME, Gao AC, Evans CP. PMID: 31341032.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    14. AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer. Mol Cancer Ther. 2019 10; 18(10):1875-1886. Liu C, Yang JC, Armstrong CM, Lou W, Liu L, Qiu X, Zou B, Lombard AP, D'Abronzo LS, Evans CP, Gao AC. PMID: 31308078; PMCID: PMC6995728.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    15. Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer. Transl Oncol. 2019 Jul; 12(7):871-878. Lombard AP, Liu C, Armstrong CM, D'Abronzo LS, Lou W, Chen H, Dall'Era M, Ghosh PM, Evans CP, Gao AC. PMID: 31075528; PMCID: PMC6510951.
      View in: PubMed   Mentions: 9  
    16. An effective density-based clustering and dynamic maintenance framework for evolving medical data streams. Int J Med Inform. 2019 06; 126:176-186. Al-Shammari A, Zhou R, Naseriparsaa M, Liu C. PMID: 31029259.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. IFNγ, a Double-Edged Sword in Cancer Immunity and Metastasis. Cancer Res. 2019 03 15; 79(6):1032-1033. Liu C, Gao AC. PMID: 30877097.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer. Nat Commun. 2018 11 16; 9(1):4700. Liu C, Lou W, Yang JC, Liu L, Armstrong CM, Lombard AP, Zhao R, Noel ODV, Tepper CG, Chen HW, Dall'Era M, Evans CP, Gao AC. PMID: 30446660; PMCID: PMC6240084.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    19. Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer. Mol Cancer Ther. 2018 10; 17(10):2197-2205. Lombard AP, Liu L, Cucchiara V, Liu C, Armstrong CM, Zhao R, Yang JC, Lou W, Evans CP, Gao AC. PMID: 29891490; PMCID: PMC6168406.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    20. ABCB1 Mediates Cabazitaxel-Docetaxel Cross-Resistance in Advanced Prostate Cancer. Mol Cancer Ther. 2017 10; 16(10):2257-2266. Lombard AP, Liu C, Armstrong CM, Cucchiara V, Gu X, Lou W, Evans CP, Gao AC. PMID: 28698198; PMCID: PMC5628132.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    21. MicroRNA-181a promotes docetaxel resistance in prostate cancer cells. Prostate. 2017 Jun; 77(9):1020-1028. Armstrong CM, Liu C, Lou W, Lombard AP, Evans CP, Gao AC. PMID: 28485104; PMCID: PMC5448975.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    22. Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer. Mol Cancer Ther. 2017 08; 16(8):1521-1530. Liu C, Armstrong CM, Lou W, Lombard AP, Cucchiara V, Gu X, Yang JC, Nadiminty N, Pan CX, Evans CP, Gao AC. PMID: 28500234; PMCID: PMC5544572.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    23. IL-25 attenuates rheumatoid arthritis through suppression of Th17 immune responses in an IL-13-dependent manner. Sci Rep. 2016 11 04; 6:36002. Liu D, Cao T, Wang N, Liu C, Ma N, Tu R, Min X. PMID: 27812008; PMCID: PMC5095710.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    24. Inhibition of AKR1C3 Activation Overcomes Resistance to Abiraterone in Advanced Prostate Cancer. Mol Cancer Ther. 2017 01; 16(1):35-44. Liu C, Armstrong CM, Lou W, Lombard A, Evans CP, Gao AC. PMID: 27794047; PMCID: PMC5222693.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    25. Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer. Oncotarget. 2016 May 31; 7(22):32210-20. Liu C, Armstrong C, Zhu Y, Lou W, Gao AC. PMID: 27049719; PMCID: PMC5078008.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    26. NF-κB2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer. Mol Cancer Ther. 2015 Aug; 14(8):1884-95. Nadiminty N, Tummala R, Liu C, Lou W, Evans CP, Gao AC. PMID: 26056150; PMCID: PMC4529751.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    27. Antiandrogens Inhibit ABCB1 Efflux and ATPase Activity and Reverse Docetaxel Resistance in Advanced Prostate Cancer. Clin Cancer Res. 2015 Sep 15; 21(18):4133-42. Zhu Y, Liu C, Armstrong C, Lou W, Sandher A, Gao AC. PMID: 25995342; PMCID: PMC4573793.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    28. Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. Prostate. 2015 Sep; 75(13):1341-53. Liu C, Lou W, Armstrong C, Zhu Y, Evans CP, Gao AC. PMID: 25970160; PMCID: PMC4536195.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    29. Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer. Cancer Res. 2015 Apr 01; 75(7):1413-22. Liu C, Lou W, Zhu Y, Yang JC, Nadiminty N, Gaikwad NW, Evans CP, Gao AC. PMID: 25649766; PMCID: PMC4383695.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    30. Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST). Prostate. 2014 Aug; 74(11):1086-94. Zhu Y, Liu C, Cui Y, Nadiminty N, Lou W, Gao AC. PMID: 24819501.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    31. Upregulation of glucose metabolism by NF-κB2/p52 mediates enzalutamide resistance in castration-resistant prostate cancer cells. Endocr Relat Cancer. 2014 Jun; 21(3):435-42. Cui Y, Nadiminty N, Liu C, Lou W, Schwartz CT, Gao AC. PMID: 24659479; PMCID: PMC4021715.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    32. Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer. Clin Cancer Res. 2014 Jun 15; 20(12):3198-3210. Liu C, Lou W, Zhu Y, Nadiminty N, Schwartz CT, Evans CP, Gao AC. PMID: 24740322; PMCID: PMC4058390.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCells
    33. Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014 Mar; 8(2):311-22. Qu S, Wang K, Xue H, Wang Y, Wu R, Liu C, Gao AC, Gout PW, Collins CC, Wang Y. PMID: 24388358; PMCID: PMC5528545.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    34. Prognostic value of cancer stem cell marker aldehyde dehydrogenase in ovarian cancer: a meta-analysis. PLoS One. 2013; 8(11):e81050. Liu S, Liu C, Min X, Ji Y, Wang N, Liu D, Cai J, Li K. PMID: 24282568; PMCID: PMC3839885.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    35. Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells. Prostate. 2014 Feb; 74(2):201-9. Liu C, Zhu Y, Lou W, Cui Y, Evans CP, Gao AC. PMID: 24307657; PMCID: PMC4437226.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    36. RhoGDIα downregulates androgen receptor signaling in prostate cancer cells. Prostate. 2013 Nov; 73(15):1614-22. Zhu Y, Liu C, Tummala R, Nadiminty N, Lou W, Gao AC. PMID: 23922223; PMCID: PMC3941975.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. Inhibition of ABCB1 expression overcomes acquired docetaxel resistance in prostate cancer. Mol Cancer Ther. 2013 Sep; 12(9):1829-36. Zhu Y, Liu C, Nadiminty N, Lou W, Tummala R, Evans CP, Gao AC. PMID: 23861346; PMCID: PMC3947549.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    38. NF-κB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants. Mol Cancer Ther. 2013 Aug; 12(8):1629-37. Nadiminty N, Tummala R, Liu C, Yang J, Lou W, Evans CP, Gao AC. PMID: 23699654; PMCID: PMC3941973.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCells
    39. Functional p53 determines docetaxel sensitivity in prostate cancer cells. Prostate. 2013 Mar; 73(4):418-27. Liu C, Zhu Y, Lou W, Nadiminty N, Chen X, Zhou Q, Shi XB, deVere White RW, Gao AC. PMID: 22996738; PMCID: PMC3938015.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    40. RhoGDIα suppresses growth and survival of prostate cancer cells. Prostate. 2012 Mar; 72(4):392-8. Zhu Y, Tummala R, Liu C, Nadiminty N, Lou W, Evans CP, Zhou Q, Gao AC. PMID: 21681778; PMCID: PMC3961824.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    41. Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion. Prostate. 2012 Jan; 72(1):82-9. Sun M, Liu C, Nadiminty N, Lou W, Zhu Y, Yang J, Evans CP, Zhou Q, Gao AC. PMID: 21538419; PMCID: PMC3938016.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    42. Intracellular glutathione content influences the sensitivity of lung cancer cell lines to methylseleninic acid. Mol Carcinog. 2012 Apr; 51(4):303-14. Liu C, Liu H, Li Y, Wu Z, Zhu Y, Wang T, Gao AC, Chen J, Zhou Q. PMID: 21520298.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    43. Andrographolide targets androgen receptor pathway in castration-resistant prostate cancer. Genes Cancer. 2011 Feb; 2(2):151-9. Liu C, Nadiminty N, Tummala R, Chun JY, Lou W, Zhu Y, Sun M, Evans CP, Zhou Q, Gao AC. PMID: 21779488; PMCID: PMC3111248.
      View in: PubMed   Mentions: 15  
    44. Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth. Genes Cancer. 2010 Aug; 1(8):868-76. Chun JY, Tummala R, Nadiminty N, Lou W, Liu C, Yang J, Evans CP, Zhou Q, Gao AC. PMID: 21442031; PMCID: PMC3063649.
      View in: PubMed   Mentions: 20  
    45. [Selenium compounds induce ROS in human high-metastatic large cell lung cancer cell line L9981.]. Zhongguo Fei Ai Za Zhi. 2008 Jun 20; 11(3):354-8. Liu C, Chen J, Wu Z, Li Y, Zhu Y, Ren Y, Zhou Q. PMID: 20731933.
      View in: PubMed   Mentions: 2     Fields:    
    46. [The study of the tumorigenicity and metastasis ability in human lung cancer cell line L9981 using in vivo imaging.]. Zhongguo Fei Ai Za Zhi. 2008 Jun 20; 11(3):321-6. Ren Y, Chen J, Liu H, Yan H, Wang Y, Liu C, Zhou Q. PMID: 20731927.
      View in: PubMed   Mentions: 3     Fields:    
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