Viswanathan V Krishnan

Title(s)Adjunct Professor, MED: Pathology & Lab Medicine
SchoolSchool of Medicine
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    1. Kalata B1 Enhances Temozolomide Toxicity to Glioblastoma Cells. Biomedicines. 2024 Sep 28; 12(10). Gerlach SL, Metcalf JS, Dunlop RA, Banack SA, Her C, Krishnan VV, Göransson U, Gunasekera S, Slazak B, Cox PA. PMID: 39457529; PMCID: PMC11505038.
      View in: PubMed   Mentions:
    2. Immunoprofiles of COVID-19 uniquely differentiated from other viruses: A machine learning investigation of multiplex immunoassay data. PNAS Nexus. 2024 Aug; 3(8):pgae327. Kaur A, Krishnan VV. PMID: 39157461; PMCID: PMC11327922.
      View in: PubMed   Mentions:
    3. Metabolomics Study at the Postharvest Conditions of Cold Storage and Fungicide (Imazalil Sulfate) Treatment in Navel Oranges and Clementine Mandarins. ACS Agric Sci Technol. 2022 Feb 21; 2(1):79-89. Montgomery KH, Brar G, Krishnan VV. PMID: 39450371; PMCID: PMC11500759.
      View in: PubMed   Mentions: 1  
    4. NMR spectroscopy analysis reveals differential metabolic responses in arabidopsis roots and leaves treated with a cytokinesis inhibitor. PLoS One. 2020; 15(11):e0241627. Wilkop TE, Wang M, Heringer A, Singh J, Zakharov F, Krishnan VV, Drakakaki G. PMID: 33156865; PMCID: PMC7647083.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    5. Validation of Enthalpy-Entropy Compensation Mechanism in Partial Amide Bond Rotation. ACS Omega. 2020 Apr 28; 5(16):9348-9355. Guerra J, Bajwa B, Kumar P, Vazquez S, Krishnan VV, Maitra S. PMID: 32363286; PMCID: PMC7191833.
      View in: PubMed   Mentions: 1  
    6. Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope. J Pept Sci. 2020 Jan; 26(1):e3229. Singh J, Her C, Supekar N, Boons GJ, Krishnan VV, Brooks CL. PMID: 31729101.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. The Ensemble of Conformations of Antifreeze Glycoproteins (AFGP8): A Study Using Nuclear Magnetic Resonance Spectroscopy. Biomolecules. 2019 06 17; 9(6). Her C, Yeh Y, Krishnan VV. PMID: 31213033; PMCID: PMC6628104.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    8. Molecular Thermodynamics Using Nuclear Magnetic Resonance (NMR) Spectroscopy. Inventions (Basel). 2019 Mar; 4(1). Krishnan VV. PMID: 31123720; PMCID: PMC6528671.
      View in: PubMed   Mentions: 5  
    9. Proteomic profiles by multiplex microsphere suspension array. J Immunol Methods. 2018 10; 461:1-14. Krishnan VV, Selvan SR, Parameswaran N, Venkateswaran N, Luciw PA, Venkateswaran KS. PMID: 30003895.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    10. Effect of sucralose on the enzyme kinetics of invertase using real-time NMR spectroscopy and progress curve analysis. Carbohydr Res. 2018 Jan 02; 455:5-9. Her C, Singh J, Krishnan VV. PMID: 29127847.
      View in: PubMed   Mentions:    Fields:    
    11. Chemistry and Chemical Equilibrium Dynamics of BMAA and Its Carbamate Adducts. Neurotox Res. 2018 Jan; 33(1):76-86. Diaz-Parga P, Goto JJ, Krishnan VV. PMID: 28921378; PMCID: PMC5834315.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    12. Ensemble characterization of an intrinsically disordered FG-Nup peptide and its F>A mutant in DMSO-d6. Biopolymers. 2017 Nov; 108(6). Reid KM, Sunanda P, Raghothama S, Krishnan VV. PMID: 28734076.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    13. Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment. Am J Pathol. 2017 Aug; 187(8):1800-1813. Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY. PMID: 28711154; PMCID: PMC5530909.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    14. Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation. Sci Rep. 2017 05 11; 7(1):1748. Sheng L, Jena PK, Liu HX, Kalanetra KM, Gonzalez FJ, French SW, Krishnan VV, Mills DA, Wan YY. PMID: 28496104; PMCID: PMC5431816.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    15. Field evaluation of a blood based test for active tuberculosis in endemic settings. PLoS One. 2017; 12(4):e0173359. Khaliq A, Ravindran R, Hussainy SF, Krishnan VV, Ambreen A, Yusuf NW, Irum S, Rashid A, Jamil M, Zaffar F, Chaudhry MN, Gupta PK, Akhtar MW, Khan IH. PMID: 28380055; PMCID: PMC5381859.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    16. Comprehensive Laboratory Evaluation of a Highly Specific Lateral Flow Assay for the Presumptive Identification of Bacillus anthracis Spores in Suspicious White Powders and Environmental Samples. Health Secur. 2016 Sep-Oct; 14(5):351-65. Ramage JG, Prentice KW, DePalma L, Venkateswaran KS, Chivukula S, Chapman C, Bell M, Datta S, Singh A, Hoffmaster A, Sarwar J, Parameswaran N, Joshi M, Thirunavkkarasu N, Krishnan V, Morse S, Avila JR, Sharma S, Estacio PL, Stanker L, Hodge DR, Pillai SP. PMID: 27661796; PMCID: PMC5041547.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    17. Upregulation of cystathionine β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury. Brain Pathol. 2017 07; 27(4):449-458. Lechpammer M, Tran YP, Wintermark P, Martínez-Cerdeño V, Krishnan VV, Ahmed W, Berman RF, Jensen FE, Nudler E, Zagzag D. PMID: 27465493; PMCID: PMC8028969.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    18. Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions. PLoS One. 2016; 11(8):e0160491. Zimmerman D, Goto JJ, Krishnan VV. PMID: 27513925; PMCID: PMC4981398.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    19. Application of data mining tools for classification of protein structural class from residue based averaged NMR chemical shifts. Biochim Biophys Acta. 2015 Oct; 1854(10 Pt A):1545-52. Kumar AV, Ali RF, Cao Y, Krishnan VV. PMID: 25758094; PMCID: PMC4547871.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    20. Data mining strategies to improve multiplex microbead immunoassay tolerance in a mouse model of infectious diseases. PLoS One. 2015; 10(1):e0116262. Mani A, Ravindran R, Mannepalli S, Vang D, Luciw PA, Hogarth M, Khan IH, Krishnan VV. PMID: 25614982; PMCID: PMC4304816.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    21. Multiplexed measurements of immunomodulator levels in peripheral blood of healthy subjects: Effects of analytical variables based on anticoagulants, age, and gender. Cytometry B Clin Cytom. 2014 Nov; 86(6):426-35. Krishnan VV, Ravindran R, Wun T, Luciw PA, Khan IH, Janatpour K. PMID: 24574151.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    22. Plasma antibody profiles in non-human primate tuberculosis. J Med Primatol. 2014 Apr; 43(2):59-71. Ravindran R, Krishnan VV, Dhawan R, Wunderlich ML, Lerche NW, Flynn JL, Luciw PA, Khan IH. PMID: 24446897.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. NMR based solvent exchange experiments to understand the conformational preference of intrinsically disordered proteins using FG-nucleoporin peptide as a model. Biopolymers. 2014 Jan; 102(1):69-77. Heisel KA, Krishnan VV. PMID: 24037535; PMCID: PMC4020917.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    24. Exploratory study on plasma immunomodulator and antibody profiles in tuberculosis patients. Clin Vaccine Immunol. 2013 Aug; 20(8):1283-90. Ravindran R, Krishnan VV, Khanum A, Luciw PA, Khan IH. PMID: 23761664; PMCID: PMC3754529.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    25. Radiation damping in modern NMR experiments: progress and challenges. Prog Nucl Magn Reson Spectrosc. 2013 Jan; 68:41-57. Krishnan VV, Murali N. PMID: 23398972; PMCID: PMC3644564.
      View in: PubMed   Mentions: 19     Fields:    
    26. Determination of Molecular Self-Diffusion Coefficients Using Pulsed-Field-Gradient NMR: An Experiment for Undergraduate Physical Chemistry Laboratory. Journal of Chemical Education. 2012 May 8; 89(6):780-783. Harmon HJ, Coffman CC, Villarrial VS, Chabolla CS, Heisel HK, Krishnan KV. .
      View in: Publisher Site   Mentions:
    27. Plasma antibody profiles as diagnostic biomarkers for tuberculosis. Clin Vaccine Immunol. 2011 Dec; 18(12):2148-53. Khan IH, Ravindran R, Krishnan VV, Awan IN, Rizvi SK, Saqib MA, Shahzad MI, Tahseen S, Ireton G, Goulding CW, Felgner P, DeRiemer K, Khanum A, Luciw PA. PMID: 21976221; PMCID: PMC3232686.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    28. Low dose radiation response curves, networks and pathways in human lymphoblastoid cells exposed from 1 to 10cGy of acute gamma radiation. Mutat Res. 2011 Jun 17; 722(2):119-30. Wyrobek AJ, Manohar CF, Krishnan VV, Nelson DO, Furtado MR, Bhattacharya MS, Marchetti F, Coleman MA. PMID: 21497671.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    29. Validation of multiplex microbead immunoassay for simultaneous serodetection of multiple infectious agents in laboratory mouse. J Immunol Methods. 2010 Dec 15; 363(1):51-9. Ravindran R, Khan IH, Krishnan VV, Ziman M, Kendall LV, Frasier JM, Bates R, Griffey SM, Fahey JR, Luciw PA. PMID: 20965193.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    30. A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins. Mol Cell Proteomics. 2010 Oct; 9(10):2205-24. Yamada J, Phillips JL, Patel S, Goldfien G, Calestagne-Morelli A, Huang H, Reza R, Acheson J, Krishnan VV, Newsam S, Gopinathan A, Lau EY, Colvin ME, Uversky VN, Rexach MF. PMID: 20368288; PMCID: PMC2953916.
      View in: PubMed   Mentions: 178     Fields:    Translation:Cells
    31. A comparison of multiplex suspension array large-panel kits for profiling cytokines and chemokines in rheumatoid arthritis patients. Cytometry B Clin Cytom. 2009 May; 76(3):159-68. Khan IH, Krishnan VV, Ziman M, Janatpour K, Wun T, Luciw PA, Tuscano J. PMID: 18823005; PMCID: PMC4425447.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    32. Multiplexed microbead immunoassays by flow cytometry for molecular profiling: Basic concepts and proteomics applications. Crit Rev Biotechnol. 2009; 29(1):29-43. Krishhan VV, Khan IH, Luciw PA. PMID: 19514901.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    33. Intramolecular cohesion of coils mediated by phenylalanine--glycine motifs in the natively unfolded domain of a nucleoporin. PLoS Comput Biol. 2008 Aug 08; 4(8):e1000145. Krishnan VV, Lau EY, Yamada J, Denning DP, Patel SS, Colvin ME, Rexach MF. PMID: 18688269; PMCID: PMC2475668.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    34. Temperature dependence of protein-hydration hydrodynamics by molecular dynamics simulations. Biophys Chem. 2007 Oct; 130(1-2):55-64. Lau EY, Krishnan VV. PMID: 17720293.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    35. A two-dimensional adsorption kinetic model for thermal hysteresis activity in antifreeze proteins. J Chem Phys. 2006 May 28; 124(20):204702. Li QZ, Yeh Y, Liu JJ, Feeney RE, Krishnan VV. PMID: 16774359.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Radiation damping in microcoil NMR probes. J Magn Reson. 2006 Apr; 179(2):294-8. Krishnan VV. PMID: 16427795.
      View in: PubMed   Mentions: 2     Fields:    
    37. Estimation of protein secondary structure content directly from NMR spectra using an improved empirical correlation with averaged chemical shift. J Struct Funct Genomics. 2005 Dec; 6(4):281-5. Mielke SP, Krishnan VV. PMID: 16283427.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    38. Brownian dynamics simulations of sequence-dependent duplex denaturation in dynamically superhelical DNA. J Chem Phys. 2005 Sep 22; 123(12):124911. Mielke SP, Grønbech-Jensen N, Krishnan VV, Fink WH, Benham CJ. PMID: 16392531.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    39. Characterization of the restricted rotation of the dimethyl groups in chemically N-terminal 13C-labeled antifreeze glycoproteins: a temperature-dependent study in water to ice through the supercooled state. J Chem Phys. 2005 Jul 22; 123(4):044702. Krishnan VV, Lau EY, Tsvetkova NM, Feeney RE, Fink WH, Yeh Y. PMID: 16095379.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    40. Application of NMR methods to identify detection reagents for use in development of robust nanosensors. Methods Mol Biol. 2005; 300:141-63. Cosman M, Krishnan VV, Balhorn R. PMID: 15657483.
      View in: PubMed   Mentions: 1     Fields:    
    41. Transcription-driven twin supercoiling of a DNA loop: a Brownian dynamics study. J Chem Phys. 2004 Oct 22; 121(16):8104-12. Mielke SP, Fink WH, Krishnan VV, Grønbech-Jensen N, Benham CJ. PMID: 15485274.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    42. An evaluation of chemical shift index-based secondary structure determination in proteins: influence of random coil chemical shifts. J Biomol NMR. 2004 Oct; 30(2):143-53. Mielke SP, Krishnan VV. PMID: 15666561.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    43. Translational dynamics of antifreeze glycoprotein in supercooled water. Biophys Chem. 2004 Aug 01; 110(3):223-30. Krishnan VV, Fink WH, Feeney RE, Yeh Y. PMID: 15228958.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    44. Protein structural class identification directly from NMR spectra using averaged chemical shifts. Bioinformatics. 2003 Nov 01; 19(16):2054-64. Mielke SP, Krishnan VV. PMID: 14594710.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    45. An empirical correlation between secondary structure content and averaged chemical shifts in proteins. Biophys J. 2003 Feb; 84(2 Pt 1):1223-7. Sibley AB, Cosman M, Krishnan VV. PMID: 12547802; PMCID: PMC1302698.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    46. Identification of novel small molecules that bind to two different sites on the surface of tetanus toxin C fragment. Chem Res Toxicol. 2002 Oct; 15(10):1218-28. Cosman M, Lightstone FC, Krishnan VV, Zeller L, Prieto MC, Roe DC, Balhorn R. PMID: 12387617.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    47. Marmoset fine B cell and T cell epitope specificities mapped onto a homology model of the extracellular domain of human myelin oligodendrocyte glycoprotein. Neurobiol Dis. 2002 Mar; 9(2):160-72. Mesleh MF, Belmar N, Lu CW, Krishnan VV, Maxwell RS, Genain CP, Cosman M. PMID: 11895369.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    48. Dynamics of antifreeze glycoproteins in the presence of ice. Biophys J. 2002 Jan; 82(1 Pt 1):464-73. Tsvetkova NM, Phillips BL, Krishnan VV, Feeney RE, Fink WH, Crowe JH, Risbud SH, Tablin F, Yeh Y. PMID: 11751333; PMCID: PMC1302486.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    49. Solution structure and backbone dynamics of the human DNA ligase IIIalpha BRCT domain. Biochemistry. 2001 Nov 06; 40(44):13158-66. Krishnan VV, Thornton KH, Thelen MP, Cosman M. PMID: 11683624.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    50. Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNA. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8507-12. Brown K, Hingerty BE, Guenther EA, Krishnan VV, Broyde S, Turteltaub KW, Cosman M. PMID: 11438709; PMCID: PMC37466.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    51. Expression, purification, and biophysical characterization of the BRCT domain of human DNA ligase IIIalpha. Protein Expr Purif. 2001 Apr; 21(3):401-11. Thornton KH, Krishnan VV, West MG, Popham J, Ramirez M, Thelen MP, Cosman M. PMID: 11281714.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    52. Dynamics of cellular retinoic acid binding protein I on multiple time scales with implications for ligand binding. Biochemistry. 2000 Aug 08; 39(31):9119-29. Krishnan VV, Sukumar M, Gierasch LM, Cosman M. PMID: 10924105.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    53. An empirical relationship between rotational correlation time and solvent accessible surface area. J Biomol NMR. 1998 Jul; 12(1):177-82. Krishnan VV, Cosman M. PMID: 20700691.
      View in: PubMed   Mentions: 13     Fields:    
    54. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 1997 Sep 29; 415(2):145-54. Hileman MR, Chapman BS, Rabizadeh S, Krishnan VV, Bredesen D, Assa-Munt N, Plesniak LA. PMID: 9350985.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    55. Calculation of coherence-transfer behavior under planar versus isotropic mixing Hamiltonians and application to heteronuclear J cross-polarization experiments in solution-state NMR spectroscopy. J Magn Reson. 1997 Jan; 124(1):205-9. Krishnan VV, Rance M. PMID: 9169214.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    56. DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architecture. Genes Dev. 1996 Jan 01; 10(1):16-26. Gaal T, Ross W, Blatter EE, Tang H, Jia X, Krishnan VV, Assa-Munt N, Ebright RH, Gourse RL. PMID: 8557191.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
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