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Robert B Rebhun

TitleASSOC PROF-SFT-VM
InstitutionUniversity of California Davis
DepartmentSurgical and Radiological Sciences
AddressCenter for Companion Animal Health
CA 95616
Phone530-754-5028
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    Collapse Research 
    Collapse Research Activities and Funding
    Enhancing natural killer immunotherapy with first-in-dog trials of inhaled recombinant IL-15 and super-agonist IL-15 in naturally occurring canine cancers
    NIH/NCI U01CA224166Sep 30, 2017 - Aug 31, 2020
    Role: Co-Principal Investigator
    The relationship between epidermal growth factor receptor and hedgehog signaling
    NIH K01OD011111Jul 15, 2011 - May 31, 2016
    Role: Principal Investigator
    The relationship between epidermal growth factor receptor and hedgehog signaling
    NIH/NCRR K01RR031272Jul 15, 2011 - May 31, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Griffin MA, Culp WTN, Rebhun RB. Lower Urinary Tract Neoplasia. Vet Sci. 2018 Nov 27; 5(4). PMID: 30486368.
      View in: PubMed
    2. Al-Nadaf S, Rebhun RB, Curran KM, Venable RO, Skorupski KA, Willcox JL, Burton JH. Retrospective analysis of doxorubicin and prednisone as first-line therapy for canine B-cell lymphoma. BMC Vet Res. 2018 Nov 20; 14(1):356. PMID: 30458771.
      View in: PubMed
    3. Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. Nat Med. 2018 Nov 12. PMID: 30420753.
      View in: PubMed
    4. Shin H, Nam A, Song KH, Lee K, Rebhun RB, Seo KW. Anticancer effects of high-dose ascorbate on canine melanoma cell lines. Vet Comp Oncol. 2018 Sep 06. PMID: 30188000.
      View in: PubMed
    5. Withers SS, Skorupski KA, York D, Choi JW, Woolard KD, Laufer-Amorim R, Sparger EE, Rodriguez CO, McSorley SJ, Monjazeb AM, Murphy WJ, Canter RJ, Rebhun RB. Association of Macrophage and Lymphocyte Infiltration with Outcome in Canine Osteosarcoma. Vet Comp Oncol. 2018 Aug 28. PMID: 30156029.
      View in: PubMed
    6. Withers SS, York D, Johnson E, Al-Nadaf S, Skorupski KA, Rodriguez CO, Burton JH, Guerrero T, Sein K, Wittenburg L, Rebhun RB. In vitro and in vivo activity of liposome-encapsulated curcumin for naturally occurring canine cancers. Vet Comp Oncol. 2018 Aug 08. PMID: 30088848.
      View in: PubMed
    7. Skorupski KA, Alarcón CN, de Lorimier LP, LaDouceur EEB, Rodriguez CO, Rebhun RB. Outcome and clinical, pathological, and immunohistochemical factors associated with prognosis for dogs with early-stage anal sac adenocarcinoma treated with surgery alone: 34 cases (2002-2013). J Am Vet Med Assoc. 2018 Jul 01; 253(1):84-91. PMID: 29911942.
      View in: PubMed
    8. Withers SS, Moore PF, Chang H, Choi JW, McSorley SJ, Kent MS, Monjazeb AM, Canter RJ, Murphy WJ, Sparger EE, Rebhun RB. Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. Dev Comp Immunol. 2018 May 31; 87:64-74. PMID: 29859828.
      View in: PubMed
    9. Kent MS, Burton JH, Dank G, Bannasch DL, Rebhun RB. Association of cancer-related mortality, age and gonadectomy in golden retriever dogs at a veterinary academic center (1989-2016). PLoS One. 2018; 13(2):e0192578. PMID: 29408871.
      View in: PubMed
    10. Park JS, Withers SS, Modiano JF, Kent MS, Chen M, Luna JI, Culp WTN, Sparger EE, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Canine cancer immunotherapy studies: linking mouse and human. J Immunother Cancer. 2016; 4:97. PMID: 28031824.
      View in: PubMed
    11. Withers SS, Lawson CM, Burton AG, Rebhun RB, Steffey MA. Management of an invasive and metastatic Sertoli cell tumor with associated myelotoxicosis in a dog. Can Vet J. 2016 Mar; 57(3):299-304. PMID: 26933269; PMCID: PMC4751774.
    12. Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson DL. Companion animals: Translational scientist's new best friends. Sci Transl Med. 2015 Oct 07; 7(308):308ps21. PMID: 26446953; PMCID: PMC4806851 [Available on 10/07/16].
    13. Shahi MH, York D, Gandour-Edwards R, Withers SS, Holt R, Rebhun RB. BMI1 is expressed in canine osteosarcoma and contributes to cell growth and chemotherapy resistance. PLoS One. 2015; 10(6):e0131006. PMID: 26110620; PMCID: PMC4482432.
    14. Culp WT, Olea-Popelka F, Sefton J, Aldridge CF, Withrow SJ, Lafferty MH, Rebhun RB, Kent MS, Ehrhart N. Evaluation of outcome and prognostic factors for dogs living greater than one year after diagnosis of osteosarcoma: 90 cases (1997-2008). J Am Vet Med Assoc. 2014 Nov 15; 245(10):1141-6. PMID: 25356715; PMCID: PMC4556346.
    15. Withers SS, Kass PH, Rodriguez CO, Skorupski KA, O'Brien D, Guerrero TA, Sein KD, Rebhun RB. Fasting Reduces the Incidence of Delayed-Type Vomiting Associated with Doxorubicin Treatment in Dogs with Lymphoma. Transl Oncol. 2014 May 12. PMID: 24831580.
      View in: PubMed
    16. Shahi MH, Holt R, Rebhun RB. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells. PLoS One. 2014; 9(5):e96593. PMID: 24810746; PMCID: PMC4014515.
    17. Lux CN, Culp WT, Mayhew PD, Tong K, Rebhun RB, Kass PH. Perioperative outcome in dogs with hemoperitoneum: 83 cases (2005-2010). J Am Vet Med Assoc. 2013 May 15; 242(10):1385-91. PMID: 23634683.
      View in: PubMed
    18. Culp WT, Ehrhart N, Withrow SJ, Rebhun RB, Boston S, Buracco P, Reiter AM, Schallberger SP, Aldridge CF, Kent MS, Mayhew PD, Brown DC. Results of surgical excision and evaluation of factors associated with survival time in dogs with lingual neoplasia: 97 cases (1995-2008). J Am Vet Med Assoc. 2013 May 15; 242(10):1392-7. PMID: 23634684.
      View in: PubMed
    19. Boostrom BO, Good KL, Maggs DJ, Rebhun RB, Johns JL, Kent MS. Unilateral intraocular mastocytosis and anterior uveitis in a dog with subcutaneous mast cell tumors. Vet Ophthalmol. 2014 Mar; 17(2):131-8. PMID: 23578200.
      View in: PubMed
    20. Seo Kw, Holt R, Jung YS, Rodriguez CO, Chen X, Rebhun RB. Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines. PLoS One. 2012; 7(8):e42960. PMID: 22927942; PMCID: PMC3424257.
    21. Rebhun RB, Kent MS, Borrofka SA, Frazier S, Skorupski K, Rodriguez CO. CHOP chemotherapy for the treatment of canine multicentric T-cell lymphoma. Vet Comp Oncol. 2011 Mar; 9(1):38-44. PMID: 21303452.
      View in: PubMed
    22. Balhorn RL, Skorupski KA, Hok S, Balhorn MC, Guerrero T, Rebhun RB. A selective high affinity ligand (SHAL) designed to bind to an over-expressed human antigen on non-Hodgkin's lymphoma also binds to canine B-cell lymphomas. Vet Immunol Immunopathol. 2010 Oct 15; 137(3-4):235-42. PMID: 20576295.
      View in: PubMed
    23. Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia. 2010 Feb; 12(2):173-82. PMID: 20126475; PMCID: PMC2814355.
    24. Rebhun RB, Thamm DH. Multiple distinct malignancies in dogs: 53 cases. J Am Anim Hosp Assoc. 2010 Jan-Feb; 46(1):20-30. PMID: 20045833.
      View in: PubMed