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Sara M Thomasy

TitleASSOC PROF-HCOMP
InstitutionUniversity of California Davis
DepartmentVM: SURG/RAD SCIENCE
Address4303 Tupper Hall
CA 95616
Phone530-752-1770
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    Collapse Research 
    Collapse Research Activities and Funding
    Respiratory and Ocular Toxicity of Inhaled Nanomaterials
    NIH/NIEHS U01ES027288Sep 1, 2016 - Aug 31, 2021
    Role: Co-Principal Investigator
    Engineering the Corneal Wound Bed to Promote Healing
    NIH/NEI K08EY021142Apr 1, 2011 - Mar 31, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Samuel M, Thomasy S, Calderon AS, Kass PH, Collins K, Murphy CJ. Effects of 5% sodium chloride ophthalmic ointment on thickness and morphology of the normal canine cornea. Vet Ophthalmol. 2018 Jun 21. PMID: 29927055.
      View in: PubMed
    2. Zarfoss MK, Tusler CA, Kass PH, Montgomery K, Lim CC, Mowat F, Thomasy S. Clinical findings and outcomes for dogs with uveodermatologic syndrome. J Am Vet Med Assoc. 2018 May 15; 252(10):1263-1271. PMID: 29701516.
      View in: PubMed
    3. Shilo-Benjamini Y, Pascoe PJ, Maggs DJ, Hollingsworth SR, Strom AR, Good KL, Thomasy S, Kass PH, Wisner ER. Retrobulbar vs peribulbar regional anesthesia techniques using bupivacaine in dogs. Vet Ophthalmol. 2018 May 15. PMID: 29762893.
      View in: PubMed
    4. Moore BA, Roux MJ, Sebbag L, Cooper A, Edwards SG, Leonard BC, Imai DM, Griffey S, Bower L, Clary D, Lloyd KCK, Hérault Y, Thomasy S, Murphy CJ, Moshiri A. A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice. Invest Ophthalmol Vis Sci. 2018 May 01; 59(6):2252-2261. PMID: 29847629.
      View in: PubMed
    5. Martin de Bustamante MG, Good KL, Leonard BC, Hollingsworth SR, Edwards SG, Knickelbein KE, Cooper AE, Thomasy S, Maggs DJ. Medical management of deep ulcerative keratitis in cats: 13 cases. J Feline Med Surg. 2018 May 01; 1098612X18770514. PMID: 29767565.
      View in: PubMed
    6. Kim S, Thomasy S, Ramsey D, Zhao M, Mannis MJ, Murphy CJ. Whorl pattern keratopathies in veterinary and human patients. Vet Ophthalmol. 2018 Feb 06. PMID: 29411482.
      View in: PubMed
    7. Thomasy S, Raghunathan VK, Miyagi H, Evashenk AT, Sermeno JC, Tripp GK, Morgan JT, Murphy CJ. Latrunculin B and substratum stiffness regulate corneal fibroblast to myofibroblast transformation. Exp Eye Res. 2018 May; 170:101-107. PMID: 29421383.
      View in: PubMed
    8. Yiu G, Wang Z, Munevar C, Tieu E, Shibata B, Wong B, Cunefare D, Farsiu S, Roberts J, Thomasy S. Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections. Exp Eye Res. 2018 Mar; 168:69-76. PMID: 29352993.
      View in: PubMed
    9. Shull OR, Reilly CM, Davis LB, Murphy CJ, Thomasy S. Phenotypic Characterization of Corneal Endothelial Dystrophy in German Shorthaired and Wirehaired Pointers Using In Vivo Advanced Corneal Imaging and Histopathology. Cornea. 2018 Jan; 37(1):88-94. PMID: 29077583.
      View in: PubMed
    10. Eaton JS, Miller PE, Bentley E, Thomasy S, Murphy CJ. The SPOTS System: An Ocular Scoring System Optimized for Use in Modern Preclinical Drug Development and Toxicology. J Ocul Pharmacol Ther. 2017 Dec; 33(10):718-734. PMID: 29239680.
      View in: PubMed
    11. Eaton JS, Miller PE, Bentley E, Thomasy S, Murphy CJ. Slit Lamp-Based Ocular Scoring Systems in Toxicology and Drug Development: A Literature Survey. J Ocul Pharmacol Ther. 2017 Dec; 33(10):707-717. PMID: 29111862.
      View in: PubMed
    12. Yiu G, Tieu E, Munevar C, Wong B, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy S. In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. Sci Rep. 2017 Nov 03; 7(1):15013. PMID: 29101353.
      View in: PubMed
    13. Miyagi H, Thomasy S, Russell P, Murphy CJ. The role of hepatocyte growth factor in corneal wound healing. Exp Eye Res. 2018 Jan; 166:49-55. PMID: 29024692.
      View in: PubMed
    14. Auten CR, Thomasy S, Kass PH, Good KL, Hollingsworth SR, Maggs DJ. Cofactors associated with Sudden Acquired Retinal Degeneration Syndrome: 151 dogs within a reference population. Vet Ophthalmol. 2018 May; 21(3):264-272. PMID: 28845542.
      View in: PubMed
    15. Brown EA, Thomasy S, Murphy CJ, Bannasch DL. Genetic analysis of optic nerve head coloboma in the Nova Scotia Duck Tolling Retriever identifies discordance with the NHEJ1 intronic deletion (collie eye anomaly mutation). Vet Ophthalmol. 2018 Mar; 21(2):144-150. PMID: 28702949.
      View in: PubMed
    16. Raghunathan VK, Thomasy S, Strøm P, Yañez-Soto B, Garland SP, Sermeno J, Reilly CM, Murphy CJ. Tissue and cellular biomechanics during corneal wound injury and repair. Acta Biomater. 2017 Aug; 58:291-301. PMID: 28559158.
      View in: PubMed
    17. Horikawa T, Thomasy S, Stanley AA, Calderon AS, Li J, Linton LL, Murphy CJ. Superficial Keratectomy and Conjunctival Advancement Hood Flap (SKCAHF) for the Management of Bullous Keratopathy: Validation in Dogs With Spontaneous Disease. Cornea. 2016 Oct; 35(10):1295-304. PMID: 27538190.
      View in: PubMed
    18. Yiu G, Vuong VS, Oltjen S, Cunefare D, Farsiu S, Garzel L, Roberts J, Thomasy S. Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2016 Oct 01; 57(13):5764-5771. PMID: 27792810.
      View in: PubMed
    19. Ali M, Raghunathan V, Li JY, Murphy CJ, Thomasy S. Biomechanical relationships between the corneal endothelium and Descemet's membrane. Exp Eye Res. 2016 11; 152:57-70. PMID: 27639516.
      View in: PubMed
    20. Thomasy S, Shull O, Outerbridge CA, Lim CC, Freeman KS, Strom AR, Kass PH, Maggs DJ. Oral administration of famciclovir for treatment of spontaneous ocular, respiratory, or dermatologic disease attributed to feline herpesvirus type 1: 59 cases (2006-2013). J Am Vet Med Assoc. 2016 Sep 01; 249(5):526-38. PMID: 27556267.
      View in: PubMed
    21. Sebbag L, Thomasy S, Woodward AP, Knych HK, Maggs DJ. Pharmacokinetic modeling of penciclovir and BRL42359 in the plasma and tears of healthy cats to optimize dosage recommendations for oral administration of famciclovir. Am J Vet Res. 2016 Aug; 77(8):833-45. PMID: 27463546.
      View in: PubMed
    22. Thomasy S, Cortes DE, Hoehn AL, Calderon AC, Li JY, Murphy CJ. In Vivo Imaging of Corneal Endothelial Dystrophy in Boston Terriers: A Spontaneous, Canine Model for Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2016 07 01; 57(9):OCT495-503. PMID: 27454658; PMCID: PMC4968913 [Available on 01/01/17].
    23. Thomasy S, Maggs DJ. A review of antiviral drugs and other compounds with activity against feline herpesvirus type 1. Vet Ophthalmol. 2016 Jul; 19 Suppl 1:119-30. PMID: 27091747; PMCID: PMC4930706 [Available on 07/01/17].
    24. Berryhill EH, Thomasy S, Kass PH, Reilly CM, Good KL, Hollingsworth SR, Maggs DJ, Magdesian KG, Pusterla N. Comparison of corneal degeneration and calcific band keratopathy from 2000 to 2013 in 69 horses. Vet Ophthalmol. 2017 Jan; 20(1):16-26. PMID: 26773714.
      View in: PubMed
    25. Thomasy S, Eaton JS, Timberlake MJ, Miller PE, Matsumoto S, Murphy CJ. Species Differences in the Geometry of the Anterior Segment Differentially Affect Anterior Chamber Cell Scoring Systems in Laboratory Animals. J Ocul Pharmacol Ther. 2016 Jan-Feb; 32(1):28-37. PMID: 26539819; PMCID: PMC4742968 [Available on 01/01/17].
    26. Winkler M, Shoa G, Tran ST, Xie Y, Thomasy S, Raghunathan VK, Murphy C, Brown DJ, Jester JV. A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2764-72. PMID: 26066606; PMCID: PMC4416662.
    27. Strom AR, Cortés DE, Thomasy S, Kass PH, Mannis MJ, Murphy CJ. In vivo ocular imaging of the cornea of the normal female laboratory beagle using confocal microscopy. Vet Ophthalmol. 2016 Jan; 19(1):63-7. PMID: 25752331; PMCID: PMC4609599 [Available on 01/01/17].
    28. Strom AR, Cortés DE, Rasmussen CA, Thomasy S, McIntyre K, Lee SF, Kass PH, Mannis MJ, Murphy CJ. In vivo evaluation of the cornea and conjunctiva of the normal laboratory beagle using time- and Fourier-domain optical coherence tomography and ultrasound pachymetry. Vet Ophthalmol. 2016 Jan; 19(1):50-6. PMID: 25676065; PMCID: PMC4586285 [Available on 01/01/17].
    29. Morgan JT, Raghunathan VK, Thomasy S, Murphy CJ, Russell P. Robust and artifact-free mounting of tissue samples for atomic force microscopy. Biotechniques. 2014 Jan; 56(1):40-2. PMID: 24447138; PMCID: PMC4322673.
    30. Freeman KS, Thomasy S, Stanley SD, Van Bonn W, Gulland F, Friedlaender AS, Maggs DJ. Population pharmacokinetics of doxycycline in the tears and plasma of northern elephant seals (Mirounga angustirostris) following oral drug administration. J Am Vet Med Assoc. 2013 Oct 15; 243(8):1170-8. PMID: 24094266.
      View in: PubMed
    31. Thomasy S, Raghunathan VK, Winkler M, Reilly CM, Sadeli AR, Russell P, Jester JV, Murphy CJ. Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium. Acta Biomater. 2014 Feb; 10(2):785-91. PMID: 24084333; PMCID: PMC4280096.
    32. Groth AD, Contreras MT, Kado-Fong HK, Nguyen KQ, Thomasy S, Maggs DJ. In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites. Vet Ophthalmol. 2014 Jul; 17(4):268-74. PMID: 24112415.
      View in: PubMed
    33. Dreier B, Thomasy S, Mendonsa R, Raghunathan VK, Russell P, Murphy CJ. Substratum compliance modulates corneal fibroblast to myofibroblast transformation. Invest Ophthalmol Vis Sci. 2013 Aug 28; 54(8):5901-7. PMID: 23860754; PMCID: PMC3757908.
    34. Wiggans KT, Vernau W, Lappin MR, Thomasy S, Maggs DJ. Diagnostic utility of aqueocentesis and aqueous humor analysis in dogs and cats with anterior uveitis. Vet Ophthalmol. 2014 May; 17(3):212-20. PMID: 23910096.
      View in: PubMed
    35. Thomasy S, Morgan JT, Wood JA, Murphy CJ, Russell P. Substratum stiffness and latrunculin B modulate the gene expression of the mechanotransducers YAP and TAZ in human trabecular meshwork cells. Exp Eye Res. 2013 Aug; 113:66-73. PMID: 23727052; PMCID: PMC3737383.
    36. Raghunathan VK, Morgan JT, Dreier B, Reilly CM, Thomasy S, Wood JA, Ly I, Tuyen BC, Hughbanks M, Murphy CJ, Russell P. Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ. Invest Ophthalmol Vis Sci. 2013 Jan 14; 54(1):378-86. PMID: 23258147; PMCID: PMC3594895.
    37. Thomasy S, Cissell DD, Arzi B, Vilches-Moure JG, Lo WY, Wisner ER, Dubielzig RR, Maggs DJ. Restrictive orbital myofibroblastic sarcoma in a cat--cross-sectional imaging (MRI & CT) appearance, treatment, and outcome. Vet Ophthalmol. 2013 Jul; 16 Suppl 1:123-9. PMID: 23281709; PMCID: PMC3620966.
    38. Thomasy S, Whittem T, Bales JL, Ferrone M, Stanley SD, Maggs DJ. Pharmacokinetics of penciclovir in healthy cats following oral administration of famciclovir or intravenous infusion of penciclovir. Am J Vet Res. 2012 Jul; 73(7):1092-9. PMID: 22738064.
      View in: PubMed
    39. Last JA, Thomasy S, Croasdale CR, Russell P, Murphy CJ. Compliance profile of the human cornea as measured by atomic force microscopy. Micron. 2012 Dec; 43(12):1293-8. PMID: 22421334; PMCID: PMC3622051.
    40. Thomasy S, Wood JA, Kass PH, Murphy CJ, Russell P. Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2012 Feb; 53(2):952-8. PMID: 22247475; PMCID: PMC3317432.
    41. Thomasy S, Covert JC, Stanley SD, Maggs DJ. Pharmacokinetics of famciclovir and penciclovir in tears following oral administration of famciclovir to cats: a pilot study. Vet Ophthalmol. 2012 Sep; 15(5):299-306. PMID: 22339892.
      View in: PubMed
    42. Wood JA, McKee CT, Thomasy S, Fischer ME, Shah NM, Murphy CJ, Russell P. Substratum compliance regulates human trabecular meshwork cell behaviors and response to latrunculin B. Invest Ophthalmol Vis Sci. 2011 Dec 02; 52(13):9298-303. PMID: 22064990; PMCID: PMC3250097.
    43. Labelle AL, Hamor RE, Townsend WM, Mitchell MA, Zarfoss MK, Breaux CB, Thomasy S, Hall T. Ophthalmic lesions in neonatal foals evaluated for nonophthalmic disease at referral hospitals. J Am Vet Med Assoc. 2011 Aug 15; 239(4):486-92. PMID: 21838586.
      View in: PubMed
    44. Thomasy S, Lim CC, Reilly CM, Kass PH, Lappin MR, Maggs DJ. Evaluation of orally administered famciclovir in cats experimentally infected with feline herpesvirus type-1. Am J Vet Res. 2011 Jan; 72(1):85-95. PMID: 21194340.
      View in: PubMed
    45. Lim CC, Reilly CM, Thomasy S, Kass PH, Maggs DJ. Effects of feline herpesvirus type 1 on tear film break-up time, Schirmer tear test results, and conjunctival goblet cell density in experimentally infected cats. Am J Vet Res. 2009 Mar; 70(3):394-403. PMID: 19254153.
      View in: PubMed
    46. Westermeyer HD, Thomasy S, Kado-Fong H, Maggs DJ. Assessment of viremia associated with experimental primary feline herpesvirus infection or presumed herpetic recrudescence in cats. Am J Vet Res. 2009 Jan; 70(1):99-104. PMID: 19119954.
      View in: PubMed
    47. Thomasy S, Mama KR, Stanley SD. Comparison of liquid chromatography-mass spectrometry and radioimmunoassay for measurement of fentanyl and determination of pharmacokinetics in equine plasma. J Anal Toxicol. 2008 Nov-Dec; 32(9):754-9. PMID: 19021930.
      View in: PubMed
    48. Thomasy S, Maggs DJ, Moulin NK, Stanley SD. Pharmacokinetics and safety of penciclovir following oral administration of famciclovir to cats. Am J Vet Res. 2007 Nov; 68(11):1252-8. PMID: 17975982.
      View in: PubMed
    49. Thomasy S, Moeller BC, Stanley SD. Comparison of opioid receptor binding in horse, guinea pig, and rat cerebral cortex and cerebellum. Vet Anaesth Analg. 2007 Sep; 34(5):351-8. PMID: 17565576.
      View in: PubMed
    50. Feary DJ, Mama KR, Thomasy S, Wagner AE, Enns RM. Influence of gastrointestinal tract disease on pharmacokinetics of lidocaine after intravenous infusion in anesthetized horses. Am J Vet Res. 2006 Feb; 67(2):317-22. PMID: 16454639.
      View in: PubMed
    51. Thomasy S, Pypendop BH, Ilkiw JE, Stanley SD. Pharmacokinetics of lidocaine and its active metabolite, monoethylglycinexylidide, after intravenous administration of lidocaine to awake and isoflurane-anesthetized cats. Am J Vet Res. 2005 Jul; 66(7):1162-6. PMID: 16111153.
      View in: PubMed
    52. Feary DJ, Mama KR, Wagner AE, Thomasy S. Influence of general anesthesia on pharmacokinetics of intravenous lidocaine infusion in horses. Am J Vet Res. 2005 Apr; 66(4):574-80. PMID: 15900935.
      View in: PubMed
    53. Thomasy S, Slovis N, Maxwell LK, Kollias-Baker C. Transdermal fentanyl combined with nonsteroidal anti-inflammatory drugs for analgesia in horses. J Vet Intern Med. 2004 Jul-Aug; 18(4):550-4. PMID: 15320597.
      View in: PubMed
    54. Bryant DL, Free RB, Thomasy S, Lapinsky DJ, Ismail KA, Arason KM, Bergmeier SC, McKay DB. Effects of methyllycaconitine and related analogues on bovine adrenal alpha3beta4* nicotinic acetylcholine receptors. Ann N Y Acad Sci. 2002 Oct; 971:139-41. PMID: 12438104.
      View in: PubMed
    55. Bryant DL, Free RB, Thomasy S, Lapinsky DJ, Ismail KA, McKay SB, Bergmeier SC, McKay DB. Structure-activity studies with ring E analogues of methyllycaconitine on bovine adrenal alpha3beta4* nicotinic receptors. Neurosci Res. 2002 Jan; 42(1):57-63. PMID: 11814609.
      View in: PubMed