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Kevin C K Lloyd

Title(s)Professor, Surgery
SchoolUniversity of California, Davis
Phone916-734-3528
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Haselimashhadi H, Mason JC, Munoz-Fuentes V, López-Gómez F, Babalola K, Acar EF, Kumar V, White J, Flenniken AM, King R, Straiton E, Seavitt JR, Gaspero A, Garza A, Christianson AE, Hsu CW, Reynolds CL, Lanza DG, Lorenzo I, Green JR, Gallegos JJ, Bohat R, Samaco RC, Veeraragavan S, Kim JK, Miller G, Fuchs H, Garrett L, Becker L, Kang YK, Clary D, Cho SY, Tamura M, Tanaka N, Soo KD, Bezginov A, About GB, Champy MF, Vasseur L, Leblanc S, Meziane H, Selloum M, Reilly PT, Spielmann N, Maier H, Gailus-Durner V, Sorg T, Hiroshi M, Yuichi O, Heaney JD, Dickinson ME, Wolfgang W, Tocchini-Valentini GP, Lloyd KCK, McKerlie C, Seong JK, Yann H, de Angelis MH, Brown SDM, Smedley D, Flicek P, Mallon AM, Parkinson H, Meehan TF. Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data. Bioinformatics. 2019 Oct 08. PMID: 31591642.
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    2. Gurumurthy CB, Lloyd KCK. Generating mouse models for biomedical research: technological advances. Dis Model Mech. 2019 01 08; 12(1). PMID: 30626588.
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    3. Modzelewski AJ, Chen S, Willis BJ, Lloyd KCK, Wood JA, He L. Efficient mouse genome engineering by CRISPR-EZ technology. Nat Protoc. 2018 06; 13(6):1253-1274. PMID: 29748649.
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    4. Moore BA, Roux MJ, Sebbag L, Cooper A, Edwards SG, Leonard BC, Imai DM, Griffey S, Bower L, Clary D, Lloyd KCK, Hérault Y, Thomasy SM, Murphy CJ, Moshiri A. A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice. Invest Ophthalmol Vis Sci. 2018 05 01; 59(6):2252-2261. PMID: 29847629.
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    5. Nutter LMJ, Heaney JD, Lloyd KCK, Murray SA, Seavitt JR, Skarnes WC, Teboul L, Brown SDM, Moore M. Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo". Nat Methods. 2018 04; 15(4):235-236. PMID: 29600991.
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    6. Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H, Hough T, Mallon AM, Wells S, Santos L, Lelliott CJ, White JK, Sorg T, Champy MF, Bower LR, Reynolds CL, Flenniken AM, Murray SA, Nutter LMJ, Svenson KL, West D, Tocchini-Valentini GP, Beaudet AL, Bosch F, Braun RB, Dobbie MS, Gao X, Herault Y, Moshiri A, Moore BA, Kent Lloyd KC, McKerlie C, Masuya H, Tanaka N, Flicek P, Parkinson HE, Sedlacek R, Seong JK, Wang CL, Moore M, Brown SD, Tschöp MH, Wurst W, Klingenspor M, Wolf E, Beckers J, Machicao F, Peter A, Staiger H, Häring HU, Grallert H, Campillos M, Maier H, Fuchs H, Gailus-Durner V, Werner T, Hrabe de Angelis M. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nat Commun. 2018 01 18; 9(1):288. PMID: 29348434.
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    7. Pol A, Renkema GH, Tangerman A, Winkel EG, Engelke UF, de Brouwer APM, Lloyd KC, Araiza RS, van den Heuvel L, Omran H, Olbrich H, Oude Elberink M, Gilissen C, Rodenburg RJ, Sass JO, Schwab KO, Schäfer H, Venselaar H, Sequeira JS, Op den Camp HJM, Wevers RA. Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Nat Genet. 2018 01; 50(1):120-129. PMID: 29255262.
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    8. Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, Krupke DM, Bertotti A, Bruna A, Brush MH, Byrne AT, Caldas C, Christie AL, Clark DA, Dowst H, Dry JR, Doroshow JH, Duchamp O, Evrard YA, Ferretti S, Frese KK, Goodwin NC, Greenawalt D, Haendel MA, Hermans E, Houghton PJ, Jonkers J, Kemper K, Khor TO, Lewis MT, Lloyd KCK, Mason J, Medico E, Neuhauser SB, Olson JM, Peeper DS, Rueda OM, Seong JK, Trusolino L, Vinolo E, Wechsler-Reya RJ, Weinstock DM, Welm A, Weroha SJ, Amant F, Pfister SM, Kool M, Parkinson H, Butte AJ, Bult CJ. PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models. Cancer Res. 2017 11 01; 77(21):e62-e66. PMID: 29092942.
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    9. Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, Bower LR, Clary DA, Meziane H, Reilly P, Minowa O, Kelsey L, Tocchini-Valentini GP, Gao X, Bradley A, Skarnes WC, Moore M, Beaudet AL, Justice MJ, Seavitt J, Dickinson ME, Wurst W, de Angelis MH, Herault Y, Wakana S, Nutter LMJ, Flenniken AM, McKerlie C, Murray SA, Svenson KL, Braun RE, West DB, Lloyd KCK, Adams DJ, White J, Karp N, Flicek P, Smedley D, Meehan TF, Parkinson HE, Teboul LM, Wells S, Steel KP, Mallon AM, Brown SDM. A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat Commun. 2017 10 12; 8(1):886. PMID: 29026089.
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    10. Karp NA, Mason J, Beaudet AL, Benjamini Y, Bower L, Braun RE, Brown SDM, Chesler EJ, Dickinson ME, Flenniken AM, Fuchs H, Angelis MH, Gao X, Guo S, Greenaway S, Heller R, Herault Y, Justice MJ, Kurbatova N, Lelliott CJ, Lloyd KCK, Mallon AM, Mank JE, Masuya H, McKerlie C, Meehan TF, Mott RF, Murray SA, Parkinson H, Ramirez-Solis R, Santos L, Seavitt JR, Smedley D, Sorg T, Speak AO, Steel KP, Svenson KL, Wakana S, West D, Wells S, Westerberg H, Yaacoby S, White JK. Prevalence of sexual dimorphism in mammalian phenotypic traits. Nat Commun. 2017 06 26; 8:15475. PMID: 28650954.
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    11. Meehan TF, Conte N, West DB, Jacobsen JO, Mason J, Warren J, Chen CK, Tudose I, Relac M, Matthews P, Karp N, Santos L, Fiegel T, Ring N, Westerberg H, Greenaway S, Sneddon D, Morgan H, Codner GF, Stewart ME, Brown J, Horner N, Haendel M, Washington N, Mungall CJ, Reynolds CL, Gallegos J, Gailus-Durner V, Sorg T, Pavlovic G, Bower LR, Moore M, Morse I, Gao X, Tocchini-Valentini GP, Obata Y, Cho SY, Seong JK, Seavitt J, Beaudet AL, Dickinson ME, Herault Y, Wurst W, de Angelis MH, Lloyd KCK, Flenniken AM, Nutter LMJ, Newbigging S, McKerlie C, Justice MJ, Murray SA, Svenson KL, Braun RE, White JK, Bradley A, Flicek P, Wells S, Skarnes WC, Adams DJ, Parkinson H, Mallon AM, Brown SDM, Smedley D. Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Nat Genet. 2017 Aug; 49(8):1231-1238. PMID: 28650483.
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    12. Zhang Y, Qian Y, Zhang J, Yan W, Jung YS, Chen M, Huang E, Lloyd K, Duan Y, Wang J, Liu G, Chen X. Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2. Genes Dev. 2017 06 15; 31(12):1243-1256. PMID: 28747430.
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    13. Moshiri A, Humpal D, Leonard BC, Imai DM, Tham A, Bower L, Clary D, Glaser TM, Lloyd KC, Murphy CJ. Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Invest Ophthalmol Vis Sci. 2017 03 01; 58(3):1709-1718. PMID: 28324111.
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    14. Choi YJ, Lin CP, Risso D, Chen S, Kim TA, Tan MH, Li JB, Wu Y, Chen C, Xuan Z, Macfarlan T, Peng W, Lloyd KC, Kim SY, Speed TP, He L. Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells. Science. 2017 02 10; 355(6325). PMID: 28082412.
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    15. Jung CJ, Zhang J, Trenchard E, Lloyd KC, West DB, Rosen B, de Jong PJ. Efficient gene targeting in mouse zygotes mediated by CRISPR/Cas9-protein. Transgenic Res. 2017 04; 26(2):263-277. PMID: 27905063.
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    16. Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA. High-throughput discovery of novel developmental phenotypes. Nature. 2016 09 22; 537(7621):508-514. PMID: 27626380.
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    17. Lloyd KC, Robinson PN, MacRae CA. Animal-based studies will be essential for precision medicine. Sci Transl Med. 2016 08 17; 8(352):352ed12. PMID: 27535618.
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    18. West DB, Engelhard EK, Adkisson M, Nava AJ, Kirov JV, Cipollone A, Willis B, Rapp J, de Jong PJ, Lloyd KC. Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. PLoS Genet. 2016 Feb; 12(2):e1005691. PMID: 26839965.
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    19. Lloyd KC, Khanna C, Hendricks W, Trent J, Kotlikoff M. Precision medicine: an opportunity for a paradigm shift in veterinary medicine. J Am Vet Med Assoc. 2016 Jan 01; 248(1):45-8. PMID: 26684088.
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    20. Lloyd KC, McKerlie C, Seong JK, Neff F. Comment on "One health, one literature: Weaving together veterinary and medical research". Sci Transl Med. 2015 Dec 09; 7(317):317le3. PMID: 26659567.
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    21. Kirov JV, Adkisson M, Nava AJ, Cipollone A, Willis B, Engelhard EK, Lloyd KC, de Jong P, West DB. Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation. PLoS One. 2015; 10(8):e0134155. PMID: 26275310.
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    22. Lloyd KC, Meehan T, Beaudet A, Murray S, Svenson K, McKerlie C, West D, Morse I, Parkinson H, Brown S, Mallon AM, Moore M. Precision medicine: Look to the mice. Science. 2015 Jul 24; 349(6246):390. PMID: 26206923.
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    23. Lloyd K, Franklin C, Lutz C, Magnuson T. Reproducibility: use mouse biobanks or lose them. Nature. 2015 Jun 11; 522(7555):151-3. PMID: 26062496.
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    24. Karp NA, Meehan TF, Morgan H, Mason JC, Blake A, Kurbatova N, Smedley D, Jacobsen J, Mott RF, Iyer V, Matthews P, Melvin DG, Wells S, Flenniken AM, Masuya H, Wakana S, White JK, Lloyd KC, Reynolds CL, Paylor R, West DB, Svenson KL, Chesler EJ, de Angelis MH, Tocchini-Valentini GP, Sorg T, Herault Y, Parkinson H, Mallon AM, Brown SD. Applying the ARRIVE Guidelines to an In Vivo Database. PLoS Biol. 2015 May; 13(5):e1002151. PMID: 25992600.
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    25. West DB, Pasumarthi RK, Baridon B, Djan E, Trainor A, Griffey SM, Engelhard EK, Rapp J, Li B, de Jong PJ, Lloyd KC. A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines. Genome Res. 2015 Apr; 25(4):598-607. PMID: 25591789.
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    26. Li MW, Willis BJ, Evans KD, Araiza RS, Lee AY, Lloyd KC. Rescue of germline transmission from chimeras by IVF after sperm analysis. Transgenic Res. 2015 Feb; 24(1):99-108. PMID: 25080098.
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    27. Lee AY, Lloyd KC. Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice. FEBS Open Bio. 2014; 4:637-42. PMID: 25161872.
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    28. Li MW, Vallelunga JM, Kinchen KL, Rink KL, Zarrabi J, Shamamian AO, Lloyd KC. IVF recovery of mutant mouse lines using sperm cryopreserved with mtg in cryovials. Cryo Letters. 2014 Mar-Apr; 35(2):145-53. PMID: 24869647.
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    29. Takeo T, Fukumoto K, Kondo T, Haruguchi Y, Takeshita Y, Nakamuta Y, Tsuchiyama S, Yoshimoto H, Shimizu N, Li MW, Kinchen K, Vallelunga J, Lloyd KC, Nakagata N. Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. Cryobiology. 2014 Feb; 68(1):12-7. PMID: 24201107.
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    30. Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, Lloyd KC, Jaksch P, Klepetko W, Weissmann N, von Melchner H. Sestrin-2, a repressor of PDGFRß signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD. Dis Model Mech. 2013 Nov; 6(6):1378-87. PMID: 24046361.
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    31. Lee AY, Evans K, Willis B, Lloyd KC. Combining sperm plug genotyping and coat color chimerism predicts germline transmission. Transgenic Res. 2013 Dec; 22(6):1265-72. PMID: 23860911.
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    32. Li MW, Kinchen KL, Vallelunga JM, Young DL, Wright KD, Gorano LN, Wasson K, Lloyd KC. Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strains. Reproduction. 2013 Mar 01; 145(3):245-54. PMID: 23315689.
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    33. Mochida K, Hasegawa A, Li MW, Fray MD, Kito S, Vallelunga JM, Lloyd KC, Yoshiki A, Obata Y, Ogura A. High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos. PLoS One. 2013; 8(1):e49316. PMID: 23341870.
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    34. Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome. 2012 Oct; 23(9-10):580-6. PMID: 22968824.
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    35. Song L, Shan Y, Lloyd KC, Cortopassi GA. Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression. Hum Mol Genet. 2012 Dec 01; 21(23):5147-58. PMID: 22949510.
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    36. Donahue LR, Hrabe de Angelis M, Hagn M, Franklin C, Lloyd KC, Magnuson T, McKerlie C, Nakagata N, Obata Y, Read S, Wurst W, Hörlein A, Davisson MT. Centralized mouse repositories. Mamm Genome. 2012 Oct; 23(9-10):559-71. PMID: 22945696.
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    37. Laughlin MR, Lloyd KC, Cline GW, Wasserman DH. NIH Mouse Metabolic Phenotyping Centers: the power of centralized phenotyping. Mamm Genome. 2012 Oct; 23(9-10):623-31. PMID: 22940748.
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    38. Li MW, Baridon B, Trainor A, Djan E, Koehne A, Griffey SM, Biggers JD, Toner M, Lloyd KC. Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype. Reproduction. 2012 Apr; 143(4):449-53. PMID: 22274886.
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    39. Lloyd KC. A knockout mouse resource for the biomedical research community. Ann N Y Acad Sci. 2011 Dec; 1245:24-6. PMID: 22211970.
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    40. Yang RY, Yu L, Graham JL, Hsu DK, Lloyd KC, Havel PJ, Liu FT. Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18696-701. PMID: 21969596.
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    41. Tomilov AA, Ramsey JJ, Hagopian K, Giorgio M, Kim KM, Lam A, Migliaccio E, Lloyd KC, Berniakovich I, Prolla TA, Pelicci P, Cortopassi GA. The Shc locus regulates insulin signaling and adiposity in mammals. Aging Cell. 2011 Feb; 10(1):55-65. PMID: 21040401.
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    42. Giritharan G, Li MW, Di Sebastiano F, De Sebastiano F, Esteban FJ, Horcajadas JA, Lloyd KC, Donjacour A, Maltepe E, Rinaudo PF. Effect of ICSI on gene expression and development of mouse preimplantation embryos. Hum Reprod. 2010 Dec; 25(12):3012-24. PMID: 20889529.
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    43. Lee AY, Lloyd KC. Rederivation of transgenic mice from iPS cells derived from frozen tissue. Transgenic Res. 2011 Feb; 20(1):167-75. PMID: 20397045.
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    44. Fazzari P, Paternain AV, Valiente M, Pla R, Luján R, Lloyd K, Lerma J, Marín O, Rico B. Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling. Nature. 2010 Apr 29; 464(7293):1376-80. PMID: 20393464.
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    45. Dadi TD, Li MW, Lloyd KC. Decreased growth factor expression through RNA interference inhibits development of mouse preimplantation embryos. Comp Med. 2009 Aug; 59(4):331-8. PMID: 19712572.
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    46. Pettitt SJ, Liang Q, Rairdan XY, Moran JL, Prosser HM, Beier DR, Lloyd KC, Bradley A, Skarnes WC. Agouti C57BL/6N embryonic stem cells for mouse genetic resources. Nat Methods. 2009 Jul; 6(7):493-5. PMID: 19525957.
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    47. Li MW, Willis BJ, Griffey SM, Spearow JL, Lloyd KC. Assessment of three generations of mice derived by ICSI using freeze-dried sperm. Zygote. 2009 Aug; 17(3):239-51. PMID: 19416557.
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    48. Elmoazzen HY, Lee GY, Li MW, McGinnis LK, Lloyd KC, Toner M, Biggers JD. Further optimization of mouse spermatozoa evaporative drying techniques. Cryobiology. 2009 Aug; 59(1):113-5. PMID: 19375415.
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    49. Barros CS, Calabrese B, Chamero P, Roberts AJ, Korzus E, Lloyd K, Stowers L, Mayford M, Halpain S, Müller U. Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Proc Natl Acad Sci U S A. 2009 Mar 17; 106(11):4507-12. PMID: 19240213.
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    50. Ergenc AF, Li MW, Toner M, Biggers JD, Lloyd KC, Olgac N. Rotationally oscillating drill (Ros-Drill) for mouse ICSI without using mercury. Mol Reprod Dev. 2008 Dec; 75(12):1744-51. PMID: 18437690.
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    51. Lloyd KC. The scientific component of residency training. J Vet Med Educ. 2008; 35(1):53-7. PMID: 18339958.
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    52. Hird DW, Lloyd KC, McCurdy SA, Schenker MB, Troidl JJ, Kass PH. Public health education at the University of California, Davis: past, present, and future programs. J Vet Med Educ. 2008; 35(2):219-24. PMID: 18723807.
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    53. Huang L, Yu YY, Kirschke CP, Gertz ER, Lloyd KK. Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation. J Biol Chem. 2007 Dec 21; 282(51):37053-63. PMID: 17954933.
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    54. Li MW, Biggers JD, Toner M, Griffey SM, Lloyd KC. Phenotypic analysis of C57BL/6J and FVB/NJ mice generated using evaporatively dried spermatozoa. Comp Med. 2007 Oct; 57(5):469-75. PMID: 17974129.
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    55. Li MW, Biggers JD, Elmoazzen HY, Toner M, McGinnis L, Lloyd KC. Long-term storage of mouse spermatozoa after evaporative drying. Reproduction. 2007 May; 133(5):919-29. PMID: 17616722.
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    56. Stephensen CB, Borowsky AD, Lloyd KC. Disruption of Rxra gene in thymocytes and T lymphocytes modestly alters lymphocyte frequencies, proliferation, survival and T helper type 1/type 2 balance. Immunology. 2007 Aug; 121(4):484-98. PMID: 17433077.
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    57. Dadi TD, Li MW, Lloyd KC. EGF and TGF-alpha supplementation enhances development of cloned mouse embryos. Cloning Stem Cells. 2007; 9(3):315-26. PMID: 17907942.
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    58. Dadi TD, Li MW, Lloyd KC. Development of mouse embryos after immunoneutralization of mitogenic growth factors mimics that of cloned embryos. Comp Med. 2006 Jun; 56(3):188-95. PMID: 16774127.
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    59. Jackson-Fisher AJ, Bellinger G, Shum E, Duong JK, Perkins AS, Gassmann M, Muller W, Kent Lloyd KC, Stern DF. Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4. Oncogene. 2006 Sep 14; 25(41):5664-72. PMID: 16652155.
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    60. Whited KL, Thao D, Lloyd KC, Kopin AS, Raybould HE. Targeted disruption of the murine CCK1 receptor gene reduces intestinal lipid-induced feedback inhibition of gastric function. Am J Physiol Gastrointest Liver Physiol. 2006 Jul; 291(1):G156-62. PMID: 16574983.
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    61. Ghashghaei HT, Weber J, Pevny L, Schmid R, Schwab MH, Lloyd KC, Eisenstat DD, Lai C, Anton ES. The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1930-5. PMID: 16446434.
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    62. Whited KL, Lu D, Tso P, Kent Lloyd KC, Raybould HE. Apolipoprotein A-IV is involved in detection of lipid in the rat intestine. J Physiol. 2005 Dec 15; 569(Pt 3):949-58. PMID: 16239275.
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    63. Golub MS, Germann SL, Araiza RS, Reader JR, Griffey SM, Lloyd KC. Movement disorders in the Hfe knockout mouse. Nutr Neurosci. 2005 Aug; 8(4):239-44. PMID: 16491649.
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    64. Escher P, Lacazette E, Courtet M, Blindenbacher A, Landmann L, Bezakova G, Lloyd KC, Mueller U, Brenner HR. Synapses form in skeletal muscles lacking neuregulin receptors. Science. 2005 Jun 24; 308(5730):1920-3. PMID: 15976301.
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    65. Patierno S, Zellalem W, Ho A, Parsons CG, Lloyd KC, Tonini M, Sternini C. N-methyl-D-aspartate receptors mediate endogenous opioid release in enteric neurons after abdominal surgery. Gastroenterology. 2005 Jun; 128(7):2009-19. PMID: 15940633.
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    66. García-Rivello H, Taranda J, Said M, Cabeza-Meckert P, Vila-Petroff M, Scaglione J, Ghio S, Chen J, Lai C, Laguens RP, Lloyd KC, Hertig CM. Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle. Am J Physiol Heart Circ Physiol. 2005 Sep; 289(3):H1153-60. PMID: 15863464.
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    67. Thuret S, Alavian KN, Gassmann M, Lloyd CK, Smits SM, Smidt MP, Klein R, Dyck RH, Simon HH. The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. J Neurochem. 2004 Dec; 91(6):1302-11. PMID: 15584907.
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    68. Anton ES, Ghashghaei HT, Weber JL, McCann C, Fischer TM, Cheung ID, Gassmann M, Messing A, Klein R, Schwab MH, Lloyd KC, Lai C. Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain. Nat Neurosci. 2004 Dec; 7(12):1319-28. PMID: 15543145.
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    69. Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B. The knockout mouse project. Nat Genet. 2004 Sep; 36(9):921-4. PMID: 15340423.
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    70. Golub MS, Germann SL, Lloyd KC. Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse. Behav Brain Res. 2004 Aug 12; 153(1):159-70. PMID: 15219717.
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    71. Villablanca A, Lubahn D, Shelby L, Lloyd K, Barthold S. Susceptibility to early atherosclerosis in male mice is mediated by estrogen receptor alpha. Arterioscler Thromb Vasc Biol. 2004 Jun; 24(6):1055-61. PMID: 15117737.
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    72. Dadi TD, Li MW, Lloyd KC. Expression levels of EGF, TGF-alpha, and EGF-R are significantly reduced in pre-implantation cloned mouse embryos. Cloning Stem Cells. 2004; 6(3):267-83. PMID: 15671673.
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    73. Long W, Wagner KU, Lloyd KC, Binart N, Shillingford JM, Hennighausen L, Jones FE. Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5. Development. 2003 Nov; 130(21):5257-68. PMID: 12954715.
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    74. Awasthi PR, French CF, Sztein J, Bedigian R, Sharp JJ, Lloyd KC. Frozen sperm as an alternative to shipping live mice. Contemp Top Lab Anim Sci. 2003 Sep; 42(5):8-11. PMID: 14510517.
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    75. Li MW, McGinnis L, Zhu L, Lawitts J, Biggers J, Lloyd KC. Intracytoplasmic sperm injection (ICSI) enables rescue of valuable mutant mouse strains. Comp Med. 2003 Jun; 53(3):265-9. PMID: 12868571.
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    76. Lloyd KC, Wang J, Solomon TE. Acid inhibition by intestinal nutrients mediated by CCK-A receptors but not plasma CCK. Am J Physiol Gastrointest Liver Physiol. 2001 Oct; 281(4):G924-30. PMID: 11557512.
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    77. Wang L, Cardin S, Martínez V, Taché Y, Lloyd KC. Duodenal loading with glucose induces fos expression in rat brain: selective blockade by devazepide. Am J Physiol. 1999 09; 277(3):R667-74. PMID: 10484482.
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    78. Zittel TT, Lloyd KC, Rothenhöfer I, Wong H, Walsh JH, Raybould HE. Calcitonin gene-related peptide and spinal afferents partly mediate postoperative colonic ileus in the rat. Surgery. 1998 May; 123(5):518-27. PMID: 9591004.
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    79. Kovacs TO, Lloyd KC, Lawson DC, Pappas TN, Walsh JH. Inhibition of sham feeding-stimulated acid secretion in dogs by immunoneutralization of gastrin. Am J Physiol. 1997 Aug; 273(2 Pt 1):G399-403. PMID: 9277419.
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    80. Lloyd KC, Amirmoazzami S, Friedik F, Chew P, Walsh JH. Somatostatin inhibits gastrin release and acid secretion by activating sst2 in dogs. Am J Physiol. 1997 Jun; 272(6 Pt 1):G1481-8. PMID: 9227485.
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    81. Lloyd KC, Amirmoazzami S, Friedik F, Heynio A, Solomon TE, Walsh JH. Candidate canine enterogastrones: acid inhibition before and after vagotomy. Am J Physiol. 1997 May; 272(5 Pt 1):G1236-42. PMID: 9176235.
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    82. Aurang K, Spraggs CF, Jordan C, Lloyd KC. Role of gastrin/CCK-B receptors in meal-stimulated acid secretion in rats. Am J Physiol. 1997 May; 272(5 Pt 1):G1243-8. PMID: 9176236.
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    83. Aurang K, Wang J, Lloyd KC. Somatostatin inhibition of acid and histamine release by activation of somatostatin receptor subtype 2 receptors in rats. J Pharmacol Exp Ther. 1997 Apr; 281(1):245-52. PMID: 9103503.
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    84. Qu XD, Lloyd KC, Walsh JH, Lehrer RI. Secretion of type II phospholipase A2 and cryptdin by rat small intestinal Paneth cells. Infect Immun. 1996 Dec; 64(12):5161-5. PMID: 8945560.
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    85. Hammond KA, Lam M, Lloyd KC, Diamond J. Simultaneous manipulation of intestinal capacities and nutrient loads in mice. Am J Physiol. 1996 Dec; 271(6 Pt 1):G969-79. PMID: 8997240.
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    86. Ohning GV, Wong HC, Lloyd KC, Walsh JH. Gastrin mediates the gastric mucosal proliferative response to feeding. Am J Physiol. 1996 Sep; 271(3 Pt 1):G470-6. PMID: 8843772.
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    87. Wong HC, Sternini C, Lloyd K, De Giorgio R, Walsh JH. Monoclonal antibody to VIP: production, characterization, immunoneutralizing activity, and usefulness in cytochemical staining. Hybridoma. 1996 Apr; 15(2):133-9. PMID: 8743293.
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    88. Hammond KA, Lloyd KC, Diamond J. Is mammary output capacity limiting to lactational performance in mice? J Exp Biol. 1996 Feb; 199(Pt 2):337-49. PMID: 8930000.
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    89. Martínez V, Coy DH, Lloyd KC, Taché Y. Intracerebroventricular injection of somatostatin sst5 receptor agonist inhibits gastric acid secretion in rats. Eur J Pharmacol. 1996 Jan 25; 296(2):153-60. PMID: 8838451.
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    90. Kovacs TO, Lloyd KC, Walsh JH. Gastrin partially mediates insulin-induced acid secretion in dogs. Peptides. 1996; 17(4):583-7. PMID: 8804065.
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    91. Lloyd KC, Grandt D, Aurang K, Eysselein VE, Schimiczek M, Reeve JR. Inhibitory effect of PYY on vagally stimulated acid secretion is mediated predominantly by Y1 receptors. Am J Physiol. 1996 Jan; 270(1 Pt 1):G123-7. PMID: 8772509.
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    92. Moldovan S, Atiya A, Adrian TE, Kleinman RM, Lloyd K, Olthoff K, Imagawa D, Shevlin L, Coy D, Walsh J. Somatostatin inhibits B-cell secretion via a subtype-2 somatostatin receptor in the isolated perfused human pancreas. J Surg Res. 1995 Jul; 59(1):85-90. PMID: 7630142.
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    93. Lloyd KC, Wang J, Aurang K, Grönhed P, Coy DH, Walsh JH. Activation of somatostatin receptor subtype 2 inhibits acid secretion in rats. Am J Physiol. 1995 Jan; 268(1 Pt 1):G102-6. PMID: 7840190.
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    94. Kovacs TO, Lloyd KC, Wong H, Walsh JH. Inhibition of bombesin-stimulated acid secretion by immunoneutralization of gastrin in dogs. Am J Physiol. 1995 Jan; 268(1 Pt 1):G54-8. PMID: 7840208.
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    95. Raybould HE, Zittel TT, Holzer HH, Lloyd KC, Meyer JH. Gastroduodenal sensory mechanisms and CCK in inhibition of gastric emptying in response to a meal. Dig Dis Sci. 1994 Dec; 39(12 Suppl):41S-43S. PMID: 7995213.
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    96. Brunicardi FC, Kleinman RM, Ohning G, Lloyd K, Gingerich R, Wong H, Walsh J. The inhibitory role of intraislet somatostatin on glucagon secretion in the isolated perfused human pancreas. Transplant Proc. 1994 Dec; 26(6):3451-2. PMID: 7998217.
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    97. Lloyd KC, Soll AH. Multiple pathways controlling acid secretion. J Gastroenterol. 1994 Jul; 29 Suppl 7:77-9. PMID: 7921159.
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    98. Lloyd KC, Soll AH. Future directions for reductionistic research in gastric secretion and defense. J Gastroenterol. 1994 Jul; 29 Suppl 7:1-5. PMID: 7921137.
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    99. Raybould HE, Lloyd KC. Integration of postprandial function in the proximal gastrointestinal tract. Role of CCK and sensory pathways. Ann N Y Acad Sci. 1994 Mar 23; 713:143-56. PMID: 8185155.
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    100. Lloyd KC. Gut hormones in gastric function. Baillieres Clin Endocrinol Metab. 1994 Jan; 8(1):111-36. PMID: 7907860.
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    101. Kleinman R, Gingerich R, Wong H, Walsh J, Lloyd K, Ohning G, De Giorgio R, Sternini C, Brunicardi FC. Use of the Fab fragment for immunoneutralization of somatostatin in the isolated perfused human pancreas. Am J Surg. 1994 Jan; 167(1):114-9. PMID: 7906098.
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    102. Lloyd KC, Maxwell V, Chuang CN, Wong HC, Soll AH, Walsh JH. Somatostatin is released in response to cholecystokinin by activation of type A CCK receptors. Peptides. 1994; 15(2):223-7. PMID: 7911992.
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    103. Buchmiller TL, Shaw KS, Chopourian HL, Lloyd KC, Gregg JP, Rivera FA, Lam ML, Diamond JM, Fonkalsrud EW. Effect of transamniotic administration of epidermal growth factor on fetal rabbit small intestinal nutrient transport and disaccharidase development. J Pediatr Surg. 1993 Oct; 28(10):1239-44. PMID: 8263680.
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    104. Chuang CN, Tanner M, Lloyd KC, Wong H, Soll AH. Endogenous somatostatin inhibits histamine release from canine gastric mucosal cells in primary culture. Am J Physiol. 1993 Sep; 265(3 Pt 1):G521-5. PMID: 7692744.
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    105. Lloyd KC. Ontogeny of gastric function vs the 'stress syndrome'. Equine Vet J. 1993 May; 25(3):179. PMID: 8508742.
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    106. Lloyd KC, Hölzer HH, Zittel TT, Raybould HE. Duodenal lipid inhibits gastric acid secretion by vagal, capsaicin-sensitive afferent pathways in rats. Am J Physiol. 1993 Apr; 264(4 Pt 1):G659-63. PMID: 8476052.
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    107. Wong HC, Taché Y, Lloyd KC, Yang H, Sternini C, Holzer P, Walsh JH. Monoclonal antibody to rat alpha-CGRP: production, characterization, and in vivo immunoneutralization activity. Hybridoma. 1993 Feb; 12(1):93-106. PMID: 8095920.
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    108. Watt PC, Ricordi C, Zeng Y, Kleinman R, Gingerich RL, Lloyd KC, Brunicardi FC. Impaired glucose response following total pancreatectomy and islet cell autotransplantation in dogs. Transplant Proc. 1992 Dec; 24(6):3026-8. PMID: 1466043.
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    109. Lloyd KC, Maxwell V, Ohning G, Walsh JH. Intestinal fat does not inhibit gastric function through a hormonal somatostatin mechanism in dogs. Gastroenterology. 1992 Oct; 103(4):1221-8. PMID: 1356872.
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    110. Lloyd KC, Raybould HE, Walsh JH. Cholecystokinin inhibits gastric acid secretion through type "A" cholecystokinin receptors and somatostatin in rats. Am J Physiol. 1992 Sep; 263(3 Pt 1):G287-92. PMID: 1357976.
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    111. Wong HC, Lloyd K, Yang H, Sternini C, Walsh JH. Preparation of a monoclonal antibody to rat alpha-CGRP for in vivo immunoneutralization of peptides. Ann N Y Acad Sci. 1992 Jun 30; 657:525-7. PMID: 1637113.
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    112. Lloyd KC, Raybould HE, Taché Y, Walsh JH. Role of gastrin, histamine, and acetylcholine in the gastric phase of acid secretion in anesthetized rats. Am J Physiol. 1992 Apr; 262(4 Pt 1):G747-55. PMID: 1348909.
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    113. Lloyd KC, Maxwell V, Kovacs TO, Miller J, Walsh JH. Cholecystokinin receptor antagonist MK-329 blocks intestinal fat-induced inhibition of meal-stimulated gastric acid secretion. Gastroenterology. 1992 Jan; 102(1):131-8. PMID: 1727746.
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    114. Furness JB, Lloyd KC, Sternini C, Walsh JH. Evidence that myenteric neurons of the gastric corpus project to both the mucosa and the external muscle: myectomy operations on the canine stomach. Cell Tissue Res. 1991 Dec; 266(3):475-81. PMID: 1811878.
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    115. Ferraris RP, Yasharpour S, Lloyd KC, Mirzayan R, Diamond JM. Luminal glucose concentrations in the gut under normal conditions. Am J Physiol. 1990 Nov; 259(5 Pt 1):G822-37. PMID: 2240224.
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    116. Lloyd KC, Stover SM, Pascoe JR, Adams P. Synovial fluid pH, cytologic characteristics, and gentamicin concentration after intra-articular administration of the drug in an experimental model of infectious arthritis in horses. Am J Vet Res. 1990 Sep; 51(9):1363-9. PMID: 2204298.
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    117. Furness JB, Lloyd KC, Sternini C, Walsh JH. Projections of substance P, vasoactive intestinal peptide and tyrosine hydroxylase immunoreactive nerve fibres in the canine intestine, with special reference to the innervation of the circular muscle. Arch Histol Cytol. 1990 May; 53(2):129-40. PMID: 1695512.
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    118. Hacker DV, Murphy CJ, Lloyd KC, Bellhorn RW, Scagliotti H. Surgical repair of collagenolytic ulcerative keratitis in the horse. Equine Vet J. 1990 Mar; 22(2):88-92. PMID: 2318187.
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    119. Lloyd KC, Wheat JD, Ryan AM, Matthews M. Ulceration in the proximal portion of the urethra as a cause of hematuria in horses: four cases (1978-1985). J Am Vet Med Assoc. 1989 May 01; 194(9):1324-6. PMID: 2722669.
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    120. Lloyd KC, Peterson PR, Wheat JD, Ryan AE, Clark JH. Keratomas in horses: seven cases (1975-1986). J Am Vet Med Assoc. 1988 Oct 15; 193(8):967-70. PMID: 3192482.
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    121. Lloyd KC, Kelly AB, Dunlop CI. Treatment of respiratory distress in a prematurely born foal. J Am Vet Med Assoc. 1988 Sep 01; 193(5):560-2. PMID: 3049490.
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    122. Nielsen IL, Jacobs KA, Huntington PJ, Chapman CB, Lloyd KC. Adverse reaction to procaine penicillin G in horses. Aust Vet J. 1988 Jun; 65(6):181-5. PMID: 3415617.
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    123. Lloyd KC, Stover SM, Pascoe JR, Baggot JD, Kurpershoek C, Hietala S. Plasma and synovial fluid concentrations of gentamicin in horses after intra-articular administration of buffered and unbuffered gentamicin. Am J Vet Res. 1988 May; 49(5):644-9. PMID: 2840005.
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    124. Lloyd KC, Stover SM, Pascoe JR, Pool RR, Kurpershoek C. Effect of gentamicin sulfate and sodium bicarbonate on the synovium of clinically normal equine antebrachiocarpal joints. Am J Vet Res. 1988 May; 49(5):650-7. PMID: 2840006.
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    125. Lloyd KC, Stover SM, Pascoe JR, Pool RR. A technique for catheterization of the equine antebrachiocarpal joint. Am J Vet Res. 1988 May; 49(5):658-62. PMID: 3395010.
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    126. Lloyd KC. Alternative diagnoses in the colic patient. Vet Clin North Am Equine Pract. 1988 Apr; 4(1):17-34. PMID: 3289694.
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    127. Lloyd KC, Koblik P, Ragle C, Wheat JD, Lakritz J. Incomplete palmar fracture of the proximal extremity of the third metacarpal bone in horses: ten cases (1981-1986). J Am Vet Med Assoc. 1988 Mar 15; 192(6):798-803. PMID: 3356600.
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    128. Lavoie JP, Morris DD, Zinkl JG, Lloyd K, Divers TJ. Pancytopenia caused by bone marrow aplasia in a horse. J Am Vet Med Assoc. 1987 Dec 01; 191(11):1462-4. PMID: 3692997.
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    129. Morris DD, Rutkowski J, Lloyd KC. Therapy in two cases of neonatal foal septicaemia and meningitis with cefotaxime sodium. Equine Vet J. 1987 Mar; 19(2):151-4. PMID: 3569200.
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    130. Paul-Murphy J, Lloyd K, Turrel JM, Blanchard PC, Gage L, Fowler M. Management of a schwannoma in the larynx of a lion. J Am Vet Med Assoc. 1986 Nov 01; 189(9):1202-3. PMID: 3505985.
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    131. Lloyd KC, Paul-Murphy J, Anderson C, Gage L, Wheat JD, Fowler M. Surgical treatment of laryngeal ossification in a tiger. J Am Vet Med Assoc. 1986 Nov 01; 189(9):1205-6. PMID: 3146564.
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    132. Fischer AT, Lloyd KC, Carlson GP, Madigan JE. Diagnostic laparoscopy in the horse. J Am Vet Med Assoc. 1986 Aug 01; 189(3):289-92. PMID: 2943716.
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    133. Lloyd KC, Harrison I, Tulleners E. Reserpine toxicosis in a horse. J Am Vet Med Assoc. 1985 May 01; 186(9):980-1. PMID: 3997654.
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    134. Lloyd KC, Morris DD. Bovine viral diarrhea in a newborn calf. J Am Vet Med Assoc. 1985 Mar 15; 186(6):600-1. PMID: 3988595.
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