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Charles B. Stephensen

TitleAdj Professor
InstitutionUniversity of California Davis
DepartmentNUTRITION
AddressWHNRC Bldg 430 W Health Sci Dr
CA 95616
Phone530-754-9266
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    Collapse Research 
    Collapse Research Activities and Funding
    Use or Metabolomic Markers of Response to Fish Oil Supplementation to Identify Ef
    NIH/NCCIH R21AT006082Sep 29, 2010 - Aug 31, 2013
    Role: Principal Investigator
    Variation in the ALOX5 gene and response to omega-3 fatty acid supplements
    NIH/NCCIH R21AT003411Sep 30, 2006 - Aug 31, 2009
    Role: Principal Investigator
    Vitamin A Regulates Th1/Th2 Development via RXR Pathway
    NIH/NIAID R01AI050863Sep 30, 2003 - Jan 31, 2009
    Role: Principal Investigator
    NUTRITION, OXIDATIVE STRESS &PROGRESSION OF HIV DISEASE
    NIH/NIAID R01AI046183Aug 1, 1999 - Jul 31, 2003
    Role: Principal Investigator
    VITAMIN A AND MUCOSAL RESPONSE TO VIRAL DIARRHEA
    NIH/FIC R03TW000425Jul 1, 1995 - Jun 30, 1999
    Role: Principal Investigator
    TESTING MUCOSAL VACCINES IN AN ANIMAL MEASLES MODEL
    NIH/NIAID R01AI035142Sep 30, 1993 - Aug 31, 1996
    Role: Principal Investigator
    REGULATION OF IGA PRODUCTION AND TRANSPORT BY VITAMIN A
    NIH/NICHD R01HD030293Apr 1, 1993 - Mar 31, 1997
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Havens PL, Tamhane A, Stephensen C, Schuster GU, Gordon CM, Liu N, Wilson C, Hosek S, Anderson PL, Kapogiannis BG, Mulligan K. Association of Vitamin D Insufficiency and Protective Tenofovir Diphosphate Concentrations with Bone Toxicity in Adolescent Boys and Young Men using Tenofovir Disoproxil Fumarate/Emtricitabine for HIV Pre-Exposure Prophylaxis. AIDS Res Hum Retroviruses. 2018 Oct 03. PMID: 30280906.
      View in: PubMed
    2. Havens PL, Long D, Schuster GU, Gordon CM, Price G, Wilson CM, Kapogiannis BG, Mulligan K, Stephensen CB. Tenofovir disoproxil fumarate appears to disrupt the relationship of vitamin D and parathyroid hormone. Antivir Ther. 2018 Sep 27. PMID: 30260797.
      View in: PubMed
    3. Krishnan S, Adams SH, Allen LH, Laugero KD, Newman JW, Stephensen CB, Burnett DJ, Witbracht M, Welch LC, Que ES, Keim NL. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes. Am J Clin Nutr. 2018 Aug 01; 108(2):266-278. PMID: 30101333.
      View in: PubMed
    4. Huda MN, Ahmad SM, Alam MJ, Khanam A, Afsar MNA, Wagatsuma Y, Raqib R, Stephensen CB, Laugero KD. Infant cortisol stress-response is associated with thymic function and vaccine response. Stress. 2018 Jun 22; 1-8. PMID: 29932814.
      View in: PubMed
    5. Havens PL, Stephensen CB, Van Loan MD, Schuster GU, Woodhouse LR, Flynn PM, Gordon CM, Pan CG, Rutledge B, Harris DR, Price G, Baker A, Meyer WA, Wilson CM, Hazra R, Kapogiannis BG, Mulligan K. Vitamin D3 Supplementation Increases Spine Bone Mineral Density in Adolescents and Young Adults With Human Immunodeficiency Virus Infection Being Treated With Tenofovir Disoproxil Fumarate: A Randomized, Placebo-Controlled Trial. Clin Infect Dis. 2018 Jan 06; 66(2):220-228. PMID: 29020329.
      View in: PubMed
    6. Jacobson DL, Stephensen CB, Miller TL, Patel K, Chen JS, Van Dyke RB, Mirza A, Schuster GU, Hazra R, Ellis A, Brummel SS, Geffner ME, Silio M, Spector SA, DiMeglio LA. Associations of Low Vitamin D and Elevated Parathyroid Hormone Concentrations With Bone Mineral Density in Perinatally HIV-Infected Children. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):33-42. PMID: 28797019.
      View in: PubMed
    7. Havens PL, Stephensen CB, Van Loan MD, Schuster GU, Woodhouse LR, Flynn PM, Gordon CM, Pan CG, Rutledge B, Liu N, Wilson CM, Hazra R, Hosek SG, Anderson PL, Seifert SM, Kapogiannis BG, Mulligan K. Decline in Bone Mass With Tenofovir Disoproxil Fumarate/Emtricitabine Is Associated With Hormonal Changes in the Absence of Renal Impairment When Used by HIV-Uninfected Adolescent Boys and Young Men for HIV Preexposure Prophylaxis. Clin Infect Dis. 2017 Feb 01; 64(3):317-325. PMID: 28013265.
      View in: PubMed
    8. Zerofsky MS, Jacoby BN, Pedersen TL, Stephensen CB. Daily Cholecalciferol Supplementation during Pregnancy Alters Markers of Regulatory Immunity, Inflammation, and Clinical Outcomes in a Randomized Controlled Trial. J Nutr. 2016 Nov; 146(11):2388-2397. PMID: 27655755.
      View in: PubMed
    9. Tanumihardjo SA, Russell RM, Stephensen CB, Gannon BM, Craft NE, Haskell MJ, Lietz G, Schulze K, Raiten DJ. Biomarkers of Nutrition for Development (BOND)-Vitamin A Review. J Nutr. 2016 09; 146(9):1816S-48S. PMID: 27511929.
      View in: PubMed
    10. Zerofsky M, Ryder M, Bhatia S, Stephensen CB, King J, Fung EB. Effects of early vitamin D deficiency rickets on bone and dental health, growth and immunity. Matern Child Nutr. 2016 10; 12(4):898-907. PMID: 25850574; PMCID: PMC4610869 [Available on 10/01/16].
    11. Raiten DJ, Sakr Ashour FA, Ross AC, Meydani SN, Dawson HD, Stephensen CB, Brabin BJ, Suchdev PS, van Ommen B. Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE). J Nutr. 2015 May; 145(5):1039S-1108S. PMID: 25833893; PMCID: PMC4448820.
    12. Huda MN, Lewis Z, Kalanetra KM, Rashid M, Ahmad SM, Raqib R, Qadri F, Underwood MA, Mills DA, Stephensen CB. Stool microbiota and vaccine responses of infants. Pediatrics. 2014 Aug; 134(2):e362-72. PMID: 25002669; PMCID: PMC4187229.
    13. Schuster GU, Bratt JM, Jiang X, Pedersen TL, Grapov D, Adkins Y, Kelley DS, Newman JW, Kenyon NJ, Stephensen CB. Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice. Am J Respir Cell Mol Biol. 2014 Mar; 50(3):626-36. PMID: 24134486; PMCID: PMC4068931.
    14. O'Sullivan A, Armstrong P, Schuster GU, Pedersen TL, Allayee H, Stephensen CB, Newman JW. Habitual diets rich in dark-green vegetables are associated with an increased response to ?-3 fatty acid supplementation in Americans of African ancestry. J Nutr. 2014 Feb; 144(2):123-31. PMID: 24259553; PMCID: PMC3901419.
    15. Livingston KA, Jiang X, Stephensen CB. CD4 T-helper cell cytokine phenotypes and antibody response following tetanus toxoid booster immunization. J Immunol Methods. 2013 Apr 30; 390(1-2):18-29. PMID: 23318779.
      View in: PubMed
    16. Havens PL, Mulligan K, Hazra R, Flynn P, Rutledge B, Van Loan MD, Lujan-Zilbermann J, Kapogiannis BG, Wilson CM, Stephensen CB. Serum 25-hydroxyvitamin D response to vitamin D3 supplementation 50,000 IU monthly in youth with HIV-1 infection. J Clin Endocrinol Metab. 2012 Nov; 97(11):4004-13. PMID: 22933542; PMCID: PMC3485594.
    17. Armstrong P, Kelley DS, Newman JW, Staggers FE, Hartiala J, Allayee H, Stephensen CB. Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans. J Nutr. 2012 Aug; 142(8):1417-28. PMID: 22739369; PMCID: PMC3397335.
    18. Stephensen CB, Zerofsky M, Burnett DJ, Lin YP, Hammock BD, Hall LM, McHugh T. Ergocalciferol from mushrooms or supplements consumed with a standard meal increases 25-hydroxyergocalciferol but decreases 25-hydroxycholecalciferol in the serum of healthy adults. J Nutr. 2012 Jul; 142(7):1246-52. PMID: 22623385.
      View in: PubMed
    19. Zunino SJ, Parelman MA, Freytag TL, Stephensen CB, Kelley DS, Mackey BE, Woodhouse LR, Bonnel EL. Effects of dietary strawberry powder on blood lipids and inflammatory markers in obese human subjects. Br J Nutr. 2012 Sep; 108(5):900-9. PMID: 22068016.
      View in: PubMed
    20. Sharkar MT, Jou MY, Hossain MB, Lönnerdal B, Stephensen CB, Raqib R. Prenatal zinc supplementation of zinc-adequate rats adversely affects immunity in offspring. J Nutr. 2011 Aug; 141(8):1559-64. PMID: 21697297.
      View in: PubMed
    21. Hartiala J, Li D, Conti DV, Vikman S, Patel Y, Tang WH, Brennan ML, Newman JW, Stephensen CB, Armstrong P, Hazen SL, Allayee H. Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet. 2011 Jun; 129(6):617-27. PMID: 21293878; PMCID: PMC3092945.
    22. Stephensen CB, Armstrong P, Newman JW, Pedersen TL, Legault J, Schuster GU, Kelley D, Vikman S, Hartiala J, Nassir R, Seldin MF, Allayee H. ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. J Lipid Res. 2011 May; 52(5):991-1003. PMID: 21296957; PMCID: PMC3073473.
    23. Liang L, Chantry C, Styne DM, Stephensen CB. Prevalence and risk factors for vitamin D deficiency among healthy infants and young children in Sacramento, California. Eur J Pediatr. 2010 Nov; 169(11):1337-44. PMID: 20532799.
      View in: PubMed
    24. Hall LM, Kimlin MG, Aronov PA, Hammock BD, Slusser JR, Woodhouse LR, Stephensen CB. Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations. J Nutr. 2010 Mar; 140(3):542-50. PMID: 20053937; PMCID: PMC2821886.
    25. Eneroth H, El Arifeen S, Persson LA, Lönnerdal B, Hossain MB, Stephensen CB, Ekström EC. Maternal multiple micronutrient supplementation has limited impact on micronutrient status of Bangladeshi infants compared with standard iron and folic acid supplementation. J Nutr. 2010 Mar; 140(3):618-24. PMID: 20053938.
      View in: PubMed
    26. Ahmad SM, Haskell MJ, Raqib R, Stephensen CB. Vitamin A status is associated with T-cell responses in Bangladeshi men. Br J Nutr. 2009 Sep; 102(6):797-802. PMID: 19747427.
      View in: PubMed
    27. Vikman S, Brena RM, Armstrong P, Hartiala J, Stephensen CB, Allayee H. Functional analysis of 5-lipoxygenase promoter repeat variants. Hum Mol Genet. 2009 Dec 01; 18(23):4521-9. PMID: 19717473; PMCID: PMC2773268.
    28. Ahmad SM, Haskell MJ, Raqib R, Stephensen CB. Markers of innate immune function are associated with vitamin a stores in men. J Nutr. 2009 Feb; 139(2):377-85. PMID: 19091796; PMCID: PMC2646203.
    29. Ahmad SM, Haskell MJ, Raqib R, Stephensen CB. Men with low vitamin A stores respond adequately to primary yellow fever and secondary tetanus toxoid vaccination. J Nutr. 2008 Nov; 138(11):2276-83. PMID: 18936231; PMCID: PMC3151440.
    30. Aronov PA, Hall LM, Dettmer K, Stephensen CB, Hammock BD. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2008 Jul; 391(5):1917-30. PMID: 18437365; PMCID: PMC3587164.
    31. Schuster GU, Kenyon NJ, Stephensen CB. Vitamin A deficiency decreases and high dietary vitamin A increases disease severity in the mouse model of asthma. J Immunol. 2008 Feb 01; 180(3):1834-42. PMID: 18209081.
      View in: PubMed
    32. Zunino SJ, Storms DH, Stephensen CB. Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice. J Nutr. 2007 May; 137(5):1216-21. PMID: 17449584.
      View in: PubMed
    33. Stephensen CB, Borowsky AD, Lloyd KC. Disruption of Rxra gene in thymocytes and T lymphocytes modestly alters lymphocyte frequencies, proliferation, survival and T helper type 1/type 2 balance. Immunology. 2007 Aug; 121(4):484-98. PMID: 17433077; PMCID: PMC2265968.
    34. Raqib R, Hossain MB, Kelleher SL, Stephensen CB, Lönnerdal B. Zinc supplementation of pregnant rats with adequate zinc nutriture suppresses immune functions in their offspring. J Nutr. 2007 Apr; 137(4):1037-42. PMID: 17374673.
      View in: PubMed
    35. Stephensen CB, Marquis GS, Douglas SD, Kruzich LA, Wilson CM. Glutathione, glutathione peroxidase, and selenium status in HIV-positive and HIV-negative adolescents and young adults. Am J Clin Nutr. 2007 Jan; 85(1):173-81. PMID: 17209194.
      View in: PubMed
    36. Stephensen CB, Marquis GS, Kruzich LA, Douglas SD, Aldrovandi GM, Wilson CM. Vitamin D status in adolescents and young adults with HIV infection. Am J Clin Nutr. 2006 May; 83(5):1135-41. PMID: 16685057.
      View in: PubMed
    37. Stephensen CB, Marquis GS, Jacob RA, Kruzich LA, Douglas SD, Wilson CM. Vitamins C and E in adolescents and young adults with HIV infection. Am J Clin Nutr. 2006 Apr; 83(4):870-9. PMID: 16600941.
      View in: PubMed
    38. Stephensen CB, Kelley DS. The innate immune system: friend and foe. Am J Clin Nutr. 2006 Feb; 83(2):187-8. PMID: 16469973.
      View in: PubMed
    39. Humphrey BD, Stephensen CB, Calvert CC, Klasing KC. Lysine deficiency and feed restriction independently alter cationic amino acid transporter expression in chickens (Gallus gallus domesticus). Comp Biochem Physiol A Mol Integr Physiol. 2006 Feb; 143(2):218-27. PMID: 16406639.
      View in: PubMed
    40. Rasooly R, Schuster GU, Gregg JP, Xiao JH, Chandraratna RA, Stephensen CB. Retinoid x receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes. J Immunol. 2005 Dec 15; 175(12):7916-29. PMID: 16339527.
      View in: PubMed
    41. Stephensen CB, Marquis GS, Douglas SD, Wilson CM. Plasma cytokines and oxidative damage in HIV-positive and HIV-negative adolescents and young adults: a protective role for IL-10? Free Radic Res. 2005 Aug; 39(8):859-64. PMID: 16036366.
      View in: PubMed
    42. Stephensen CB, Marquis GS, Douglas SD, Wilson CM. Immune activation and oxidative damage in HIV-positive and HIV-negative adolescents. J Acquir Immune Defic Syndr. 2005 Feb 01; 38(2):180-90. PMID: 15671803.
      View in: PubMed
    43. Stephensen CB. Fish oil and inflammatory disease: is asthma the next target for n-3 fatty acid supplements? Nutr Rev. 2004 Dec; 62(12):486-9. PMID: 15648824.
      View in: PubMed
    44. Stephensen CB, Jiang X, Freytag T. Vitamin A deficiency increases the in vivo development of IL-10-positive Th2 cells and decreases development of Th1 cells in mice. J Nutr. 2004 Oct; 134(10):2660-6. PMID: 15465763.
      View in: PubMed
    45. Humphrey BD, Stephensen CB, Calvert CC, Klasing KC. Glucose and cationic amino acid transporter expression in growing chickens (Gallus gallus domesticus). Comp Biochem Physiol A Mol Integr Physiol. 2004 Aug; 138(4):515-25. PMID: 15369841.
      View in: PubMed
    46. Stephensen CB. Commentary: A hypothesis concerning vitamin A supplementation, vaccines, and childhood mortality. Int J Epidemiol. 2003 Oct; 32(5):828-9. PMID: 14559759.
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    47. Stephensen CB. Vitamin A, beta-carotene, and mother-to-child transmission of HIV. Nutr Rev. 2003 Aug; 61(8):280-4. PMID: 13677590.
      View in: PubMed
    48. Jacob RA, Aiello GM, Stephensen CB, Blumberg JB, Milbury PE, Wallock LM, Ames BN. Moderate antioxidant supplementation has no effect on biomarkers of oxidant damage in healthy men with low fruit and vegetable intakes. J Nutr. 2003 Mar; 133(3):740-3. PMID: 12612146.
      View in: PubMed
    49. Drammeh BS, Marquis GS, Funkhouser E, Bates C, Eto I, Stephensen CB. A randomized, 4-month mango and fat supplementation trial improved vitamin A status among young Gambian children. J Nutr. 2002 Dec; 132(12):3693-9. PMID: 12468609.
      View in: PubMed
    50. Stephensen CB, Rasooly R, Jiang X, Ceddia MA, Weaver CT, Chandraratna RA, Bucy RP. Vitamin A enhances in vitro Th2 development via retinoid X receptor pathway. J Immunol. 2002 May 01; 168(9):4495-503. PMID: 11970994.
      View in: PubMed