Amparo C Villablanca

Title(s)Professor, Cardiovascular Medicine
SchoolUniversity of California, Davis
AddressOne Shields Ave, TB 172
CA 95616
Phone530-752-0718
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    1. Relationship Between Age at Menopause, Obesity, and Incident Heart Failure: The Atherosclerosis Risk in Communities Study. J Am Heart Assoc. 2022 Apr 19; 11(8):e024461. Ebong IA, Wilson MD, Appiah D, Michos ED, Racette SB, Villablanca A, Breathett K, Lutsey PL, Wellons M, Watson KE, Chang P, Bertoni AG. PMID: 35416049.
      View in: PubMed   Mentions:
    2. Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction. Nutrients. 2021 Nov 01; 13(11). Nuthikattu S, Milenkovic D, Norman JE, Rutledge J, Villablanca A. PMID: 34836168; PMCID: PMC8622784.
      View in: PubMed   Mentions:
    3. Integrated Multi-Omic Analyses of the Genomic Modifications by Gut Microbiome-Derived Metabolites of Epicatechin, 5-(4'-Hydroxyphenyl)-γ-Valerolactone, in TNFalpha-Stimulated Primary Human Brain Microvascular Endothelial Cells. Front Neurosci. 2021; 15:622640. Corral-Jara KF, Nuthikattu S, Rutledge J, Villablanca A, Morand C, Schroeter H, Milenkovic D. PMID: 33841078; PMCID: PMC8033932.
      View in: PubMed   Mentions: 1  
    4. Sex-Dependent Molecular Mechanisms of Lipotoxic Injury in Brain Microvasculature: Implications for Dementia. Int J Mol Sci. 2020 Oct 31; 21(21). Nuthikattu S, Milenkovic D, Rutledge JC, Villablanca AC. PMID: 33142695; PMCID: PMC7663125.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Lipotoxic Injury Differentially Regulates Brain Microvascular Gene Expression in Male Mice. Nutrients. 2020 Jun 13; 12(6). Nuthikattu S, Milenkovic D, Rutledge JC, Villablanca AC. PMID: 32545722; PMCID: PMC7353447.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. The Western Diet Regulates Hippocampal Microvascular Gene Expression: An Integrated Genomic Analyses in Female Mice. Sci Rep. 2019 12 13; 9(1):19058. Nuthikattu S, Milenkovic D, Rutledge J, Villablanca A. PMID: 31836762; PMCID: PMC6911042.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    7. A Summary Report from the Research Partnership on Women in Science Careers. J Gen Intern Med. 2019 03; 34(3):356-362. Carr PL, Helitzer D, Freund K, Westring A, McGee R, Campbell PB, Wood CV, Villablanca A. PMID: 30003480; PMCID: PMC6420545.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Barriers to Career Flexibility in Academic Medicine: A Qualitative Analysis of Reasons for the Underutilization of Family-Friendly Policies, and Implications for Institutional Change and Department Chair Leadership. Acad Med. 2018 02; 93(2):246-255. Shauman K, Howell LP, Paterniti DA, Beckett LA, Villablanca AC. PMID: 28834844; PMCID: PMC5788717.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Developing Diverse Leaders at Academic Health Centers: A Prerequisite to Quality Health Care? Am J Med Qual. 2018 07; 33(4):440-442. Shaikh U, Acosta DA, Freischlag JA, Young HM, Villablanca AC. PMID: 29027473.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Advances in Cardiovascular Health in Women over the Past Decade: Guideline Recommendations for Practice. J Womens Health (Larchmt). 2018 02; 27(2):128-139. Raeisi-Giglou P, Volgman AS, Patel H, Campbell S, Villablanca A, Hsich E. PMID: 28714810; PMCID: PMC5815443.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    11. Ideal Worker and Academic Professional Identity: Perspectives from a Career Flexibility Educational Intervention. Am J Med. 2017 09; 130(9):1117-1125. Howell LP, Beckett LA, Villablanca AC. PMID: 28625409.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Where Are the Women? The Underrepresentation of Women Physicians Among Recognition Award Recipients From Medical Specialty Societies. PM R. 2017 Aug; 9(8):804-815. Silver JK, Slocum CS, Bank AM, Bhatnagar S, Blauwet CA, Poorman JA, Villablanca A, Parangi S. PMID: 28606837.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    13. Introduction from the Guest Editors. Journal of Women's Health. 2017 May 1; 26(5):524-524. Villablanca VA, Helitzer HD, Carr CP, for the Research Partnership on Wom f. .
      View in: Publisher Site   Mentions:
    14. Evaluating a Medical School's Climate for Women's Success: Outcomes for Faculty Recruitment, Retention, and Promotion. J Womens Health (Larchmt). 2017 05; 26(5):530-539. Villablanca AC, Li Y, Beckett LA, Howell LP. PMID: 28170291; PMCID: PMC5446601.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Outcomes of a Clinic-Based Educational Intervention for Cardiovascular Disease Prevention by Race, Ethnicity, and Urban/Rural Status. J Womens Health (Larchmt). 2016 11; 25(11):1174-1186. Villablanca AC, Slee C, Lianov L, Tancredi D. PMID: 27356155; PMCID: PMC5116690.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Retention of Women Faculty in Academia: Ensuring Success. J Womens Health (Larchmt). 2016 07; 25(7):662-3. Villablanca AC, Howell LP. PMID: 27268277.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways. J Lipid Res. 2016 06; 57(6):955-68. Aung HH, Altman R, Nyunt T, Kim J, Nuthikattu S, Budamagunta M, Voss JC, Wilson D, Rutledge JC, Villablanca AC. PMID: 27087439; PMCID: PMC4878181.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. The Role of Compensation Criteria to Minimize Face-Time Bias and Support Faculty Career Flexibility: An Approach to Enhance Career Satisfaction in Academic Pathology. Acad Pathol. 2016 Jan-Dec; 3:2374289515628024. Howell LP, Elsbach KD, Villablanca AC. PMID: 28725757; PMCID: PMC5497863.
      View in: PubMed   Mentions: 3  
    19. Inflammation and Cardiometabolic Risk in African American Women Is Reduced by a Pilot Community-Based Educational Intervention. J Womens Health (Larchmt). 2016 Feb; 25(2):188-99. Villablanca AC, Warford C, Wheeler K. PMID: 26263081.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Do Family Responsibilities and a Clinical Versus Research Faculty Position Affect Satisfaction with Career and Work-Life Balance for Medical School Faculty? J Womens Health (Larchmt). 2015 Jun; 24(6):471-80. Beckett L, Nettiksimmons J, Howell LP, Villablanca AC. PMID: 26070036; PMCID: PMC4490748.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    21. Gender differences in experiences of K-awardees: beyond space, resources and science. J Gen Intern Med. 2015 Apr; 30(4):381-3. Villablanca AC, Howell LP. PMID: 25666209; PMCID: PMC4371004.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. The Women in Medicine and Health Science program: an innovative initiative to support female faculty at the University of California Davis School of Medicine. Acad Med. 2014 Nov; 89(11):1462-6. Bauman MD, Howell LP, Villablanca AC. PMID: 25006704; PMCID: PMC4213297.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    23. Community-based cardiovascular disease prevention to reduce cardiometabolic risk in Latina women: a pilot program. J Womens Health (Larchmt). 2014 Apr; 23(4):350-7. Altman R, Nunez de Ybarra J, Villablanca AC. PMID: 24552357; PMCID: PMC3992003.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    24. Improving knowledge, awareness, and use of flexible career policies through an accelerator intervention at the University of California, Davis, School of Medicine. Acad Med. 2013 Jun; 88(6):771-7. Villablanca AC, Beckett L, Nettiksimmons J, Howell LP. PMID: 23619063; PMCID: PMC3665650.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Testosterone-derived estradiol production by male endothelium is robust and dependent on p450 aromatase via estrogen receptor alpha. Springerplus. 2013 Dec; 2(1):214. Villablanca AC, Tetali S, Altman R, Ng KF, Rutledge JC. PMID: 23741647; PMCID: PMC3667361.
      View in: PubMed   Mentions: 3  
    26. Murine cytomegalovirus (MCMV) infection upregulates P38 MAP kinase in aortas of Apo E KO mice: a molecular mechanism for MCMV-induced acceleration of atherosclerosis. J Cardiovasc Transl Res. 2013 Feb; 6(1):54-64. Tang-Feldman YJ, Lochhead SR, Lochhead GR, Yu C, George M, Villablanca AC, Pomeroy C. PMID: 23192592; PMCID: PMC4591060.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    27. Generational and gender perspectives on career flexibility: ensuring the faculty workforce of the future. Am J Med. 2012 Jul; 125(7):719-28. Howell LP, Beckett LA, Nettiksimmons J, Villablanca AC. PMID: 22727238; PMCID: PMC4131696.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    28. Career flexibility and family-friendly policies: an NIH-funded study to enhance women's careers in biomedical sciences. J Womens Health (Larchmt). 2011 Oct; 20(10):1485-96. Villablanca AC, Beckett L, Nettiksimmons J, Howell LP. PMID: 21859346; PMCID: PMC3186447.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    29. The DHHS Office on Women's Health Initiative to Improve Women's Heart Health: focus on knowledge and awareness among women with cardiometabolic risk factors. J Womens Health (Larchmt). 2011 Jun; 20(6):893-900. Giardina EG, Sciacca RR, Foody JM, D'Onofrio G, Villablanca AC, Leatherwood S, Taylor AL, Haynes SG. PMID: 21492002; PMCID: PMC3113416.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    30. Atherosclerosis and sex hormones: current concepts. Clin Sci (Lond). 2010 Dec; 119(12):493-513. Villablanca AC, Jayachandran M, Banka C. PMID: 20958265.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    31. Maternal and neonatal exposure to environmental tobacco smoke targets pro-inflammatory genes in neonatal arteries. J Cardiovasc Transl Res. 2010 Dec; 3(6):696-703. Villablanca AC, Pinkerton KE, Rutledge JC. PMID: 20890690; PMCID: PMC2993896.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    32. Outcomes of comprehensive heart care programs in high-risk women. J Womens Health (Larchmt). 2010 Jul; 19(7):1313-25. Villablanca AC, Beckett LA, Li Y, Leatherwood S, Gill SK, Giardina EG, Taylor AL, Barron C, Foody JM, Haynes S, D'Onofrio G. PMID: 20590484; PMCID: PMC2940459.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. The Office on Women's Health initiative to improve women's heart health: program description, site characteristics, and lessons learned. J Womens Health (Larchmt). 2010 Mar; 19(3):507-16. Foody JM, Villablanca AC, Giardina EG, Gill S, Taylor AL, Leatherwood S, Haynes SG, D'Onofrio G. PMID: 20158403.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Postprandial metabolic responses to dietary glycemic index in hypercholesterolemic postmenopausal women. Prev Cardiol. 2010; 13(1):29-35. Bukkapatnam RN, Berglund L, Anuurad E, Devaraj S, Hyson D, Rafii F, Malmstein C, Villablanca AC. PMID: 20021624; PMCID: PMC3613123.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    35. This issue includes more than a conventional discussion of heart disease in women. J Cardiovasc Transl Res. 2009 Sep; 2(3):227. Banka CL, Villablanca A. PMID: 19654886; PMCID: PMC2719732.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    36. Outcomes of national community organization cardiovascular prevention programs for high-risk women. J Cardiovasc Transl Res. 2009 Sep; 2(3):306-20. Villablanca AC, Arline S, Lewis J, Raju S, Sanders S, Carrow S. PMID: 19654887; PMCID: PMC2719733.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    37. 17beta-estradiol prevents early-stage atherosclerosis in estrogen receptor-alpha deficient female mice. J Cardiovasc Transl Res. 2009 Sep; 2(3):289-99. Villablanca AC, Tenwolde A, Lee M, Huck M, Mumenthaler S, Rutledge JC. PMID: 19654889; PMCID: PMC2719738.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    38. Compromised aortic vasoreactivity in male estrogen receptor-alpha-deficient mice during acute lipopolysaccharide-induced inflammation. Endocrinology. 2007 Mar; 148(3):1403-11. Corbacho AM, Eiserich JP, Zuniga LA, Valacchi G, Villablanca AC. PMID: 17158209.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    39. Hyperglycemia and loss of ovarian hormones mediate atheroma formation through endothelial layer disruption and increased permeability. Am J Physiol Regul Integr Comp Physiol. 2007 Feb; 292(2):R723-30. Benton J, Powers A, Eiselein L, Fitch R, Wilson D, Villablanca AC, Rutledge JC. PMID: 17272672.
      View in: PubMed   Mentions: 1  Translation:Animals
    40. Chronic consumption of flavanol-rich cocoa improves endothelial function and decreases vascular cell adhesion molecule in hypercholesterolemic postmenopausal women. J Cardiovasc Pharmacol. 2006; 47 Suppl 2:S177-86; discussion S206-9. Wang-Polagruto JF, Villablanca AC, Polagruto JA, Lee L, Holt RR, Schrader HR, Ensunsa JL, Steinberg FM, Schmitz HH, Keen CL. PMID: 16794456.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    41. Susceptibility to early atherosclerosis in male mice is mediated by estrogen receptor alpha. Arterioscler Thromb Vasc Biol. 2004 Jun; 24(6):1055-61. Villablanca A, Lubahn D, Shelby L, Lloyd K, Barthold S. PMID: 15117737.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    42. Cardiovascular actions of selective estrogen receptor modulators and phytoestrogens. Prev Cardiol. 2004; 7(2):73-9. Nandur R, Kumar K, Villablanca AC. PMID: 15133375.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    43. Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am J Clin Nutr. 2003 Jul; 78(1):123-30. Steinberg FM, Guthrie NL, Villablanca AC, Kumar K, Murray MJ. PMID: 12816781.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCellsCTClinical Trials
    44. Differential regulation of gene expression by ovariectomy in mouse aorta. Physiol Genomics. 2003 Feb 06; 12(3):175-85. Villablanca AC, Lewis KA, Tham D, Rutledge JC. PMID: 12464683.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    45. Time- and dose-dependent differential upregulation of three genes by 17 beta-estradiol in endothelial cells. J Appl Physiol (1985). 2002 Mar; 92(3):1064-73. Villablanca AC, Lewis KA, Rutledge JC. PMID: 11842041.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    46. Estrogens and lipids. Can HRT designer estrogens, and phytoestrogens reduce cardiovascular risk markers after menopause? Postgrad Med. 2002 Jan; 111(1):23-30; quiz 3. Ariyo AA, Villablanca AC. PMID: 11810749.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Smoking and cardiovascular disease. Clin Chest Med. 2000 Mar; 21(1):159-72. Villablanca AC, McDonald JM, Rutledge JC. PMID: 10763097.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsPHPublic Health
    48. Heart disease during pregnancy. Which cardiovascular changes reflect disease? Postgrad Med. 1998 Nov; 104(5):149-56. Villablanca AC. PMID: 9823391.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Heart disease during pregnancy. Which cardiovascular changes are normal or transient? Postgrad Med. 1998 Oct; 104(4):183-4, 187-92. Villablanca AC. PMID: 9793564.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Nicotine stimulates DNA synthesis and proliferation in vascular endothelial cells in vitro. J Appl Physiol (1985). 1998 Jun; 84(6):2089-98. Villablanca AC. PMID: 9609804.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    51. 17beta-estradiol stimulates substance P receptor gene expression. Mol Cell Endocrinol. 1997 Dec 12; 135(2):109-17. Villablanca AC, Hanley MR. PMID: 9484906.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. Substance P stimulates vascular endothelial cellular reducing capacity in the presence of insulin and human plasma factors. J Cell Biochem. 1997 Sep 15; 66(4):471-81. Villablanca AC, Reid TW. PMID: 9282325.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    53. Inducible receptors. Trends Pharmacol Sci. 1997 May; 18(5):171-81. Donaldson LF, Hanley MR, Villablanca AC. PMID: 9184478.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    54. Coronary heart disease in women. Gender differences and effects of menopause. Postgrad Med. 1996 Sep; 100(3):191-6, 201-2. Villablanca AC. PMID: 8795654.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    55. Substance P increases microvascular permeability via nitric oxide-mediated convective pathways. Am J Physiol. 1995 Apr; 268(4 Pt 2):R1060-8. Nguyen LS, Villablanca AC, Rutledge JC. PMID: 7537470.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    56. Growth-promoting effects of substance P on endothelial cells in vitro. Synergism with calcitonin gene-related peptide, insulin, and plasma factors. Circ Res. 1994 Dec; 75(6):1113-20. Villablanca AC, Murphy CJ, Reid TW. PMID: 7525104.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    57. Bronchial vasodilation by histamine in sheep: characterization of receptor subtype. J Appl Physiol (1985). 1992 Jun; 72(6):2090-8. Parsons GH, Villablanca AC, Brock JM, Howard RS, Colbert SR, Nichol GM, Chung KF. PMID: 1629060.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
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