Charles DeCarli

Title(s)Professor, Neurology
SchoolSchool of Medicine
AddressACC/UCDMC
CA 95817
Phone916-734-8413
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    Collapse Biography 
    Collapse Education and Training
    UC Santa Barbara, Goleta, CABS06/1978Physiological Psychology
    George Washington University, Washington, D.C.MD06/1982M.D.
    George Washington University, Washington, D.C.06/1984Internal Medicine
    Strong Memorial Hospital, Rochester, N.Y.06/1987Neurology
    National Institute on Aging, Laboratory of Neuroscience, Section on Brain Aging and Dementia, NIH07/1990Dementia Fellowship
    Collapse Awards and Honors
    , Department of Medicine, George Washington University1982  - 1983Department Improvement Fund for Laboratory Research
    University of Pennsylvania1998Bayer Visiting Professor
    Department of Neurology, University of Kansas1999Resident Education Teaching Award
    Department of Neurology, University of Kansas2000Resident Education Teaching Award
    University of Rochester2003Department of Neurology Alumni Award
    Department of Neurology, UC Davis2004Outstanding Teacher of the Year
    University of California, Davis2008Dean’s Excellence in Research Mentoring Award
    Roberts Research Institute, University of Ontario2010J. Allyn Taylor International Prize in Medicine—Imaging of the Aging Brain
    Department of Neurology, Mayo Clinic2012Mayo Clinic Visiting Professor
    University of California, Davis2012Victor and Genevieve Orsi Chair in Alzheimer’s Research
    Department of Neurology, UC Davis2014Resident Education Teaching Award
    University of California, Davis2018UC Davis School of Medicine Research Award
    University of California, Davis2019Distinguished Professor of Neurology
    Trinity Episcopal Cathedral, diocese of Northern California2019Eucharistic Minister

    Collapse Overview 
    Collapse Overview
    Charles DeCarli, MD, is Distinguished Professor of Neurology at the University of California in Davis, California and recipient of the Victor and Genevieve Orsi Chair in Alzheimer’s Research. He is the Director of the UC Davis Alzheimer’s Disease Center, a United States National Institutes of Health funded Alzheimer’s research center. He is also Director of the Imaging of Dementia and Aging (IDeA) laboratory. His research focuses on using advanced structural and functional brain imaging to study normal aging, mild cognitive impairment and dementia and the role of genetics, diversity, cerebrovascular and Alzheimer’s disease on these processes. He is a recipient of the J. Allyn Taylor International Prize in Medicine—Imaging of the Aging Brain in recognition of his work. Dr. DeCarli is currently funded as principal, or co-principal investigator on 8 National Institute of Aging or National Institute of Neurological Disorders and Stroke grants and is the principal investigator of the Neuroscience of Cognitive Aging T32 training grant.

    Collapse Research 
    Collapse Research Activities and Funding
    UC Davis Alzheimer's Disease Research Center
    NIH P30AG072972Aug 15, 2021 - Jun 30, 2026
    Role: Principal Investigator
    The Clinical Significance of Incidental White Matter Lesions on MRI Amongst a Diverse Population with Cognitive Complaints (INDEED)
    NIH U19NS120384Sep 30, 2020 - Aug 31, 2026
    Role: Principal Investigator
    MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of Latinos
    NIH RF1AG054548Jul 15, 2017 - Mar 31, 2022
    Role: Principal Investigator
    Novel imaging and endothelial biomarkers of small vessel cerebrovascular disease
    NIH UH3NS100608Sep 30, 2016 - Jul 31, 2021
    Role: Co-Principal Investigator
    Novel imaging and endothelial biomarkers of small vessel cerebrovascular disease
    NIH UH2NS100608Sep 30, 2016 - Jul 31, 2018
    Role: Co-Principal Investigator
    Temporal Trends, Novel Imaging and Molecular Characterization of Preclinical and Clinical Alzheimer's Disease in the Framingham Cohorts
    NIH R01AG054076Sep 1, 2016 - May 31, 2021
    Role: Co-Principal Investigator
    Lifecourse health, cerebral pathology and ethnic disparities in dementia
    NIH RF1AG052132Jun 1, 2016 - May 31, 2021
    Role: Co-Principal Investigator
    Neuroscience of Cognitive Aging
    NIH T32AG050061May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Study of Latinos Investigation of Neurocognitive Aging 2
    NIH R56AG048642Sep 1, 2015 - Apr 30, 2022
    Role: Co-Principal Investigator
    The impact of non-amyloid processes on cognitive aging
    NIH R01AG047827Sep 15, 2014 - Apr 30, 2020
    Role: Principal Investigator
    NRF2 Anti-Oxidant Systems and White Matter Hyperintensities
    NIH R01AG042292Apr 1, 2013 - Mar 31, 2019
    Role: Co-Principal Investigator
    Heterogeneity of Mild Cognitive Impairment (MCI)
    NIH R01AG021028Jul 1, 2002 - May 31, 2016
    Role: Principal Investigator
    UC Davis Alzheimer's Disease Core Center
    NIH P30AG010129Sep 30, 1991 - Jun 30, 2021
    Role: Principal Investigator
    ALZHEIMERS DISEASE CENTER CORE GRANT
    NIH P30AG010182Sep 30, 1991 - Jun 30, 1999
    Role: Principal Investigator
    Precursors of Stroke Incidence and Prognosis
    NIH R01NS017950Dec 1, 1981 - Feb 28, 2021
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury. Alzheimers Res Ther. 2023 Sep 12; 15(1):154. Vered S, Beiser AS, Sulimani L, Sznitman S, Gonzales MM, Aparicio HJ, DeCarli C, Scott MR, Ghosh S, Lewitus GM, Meiri D, Seshadri S, Weinstein G. PMID: 37700370; PMCID: PMC10496329.
      View in: PubMed   Mentions:
    2. A polygenic risk score for Alzheimer's disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S. Alzheimers Res Ther. 2023 Aug 30; 15(1):146. Sofer T, Kurniansyah N, Granot-Hershkovitz E, Goodman MO, Tarraf W, Broce I, Lipton RB, Daviglus M, Lamar M, Wassertheil-Smoller S, Cai J, DeCarli CS, Gonzalez HM, Fornage M. PMID: 37649099; PMCID: PMC10469805.
      View in: PubMed   Mentions:
    3. Association of MRI Visible Perivascular Spaces and Neurofilament Light Chain: The Framingham Heart Study. J Alzheimers Dis. 2023 Aug 28. Ekenze O, Pinheiro A, Demissie S, Aparicio HJ, Charidimou A, Beiser AS, Satizabal CL, Kautz T, DeCarli C, Greenberg S, Seshadri S, Romero JR. PMID: 37661877.
      View in: PubMed   Mentions:
    4. Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study. Sci Rep. 2023 08 21; 13(1):13622. Fongang B, Satizabal C, Kautz TF, Wadop YN, Muhammad JAS, Vasquez E, Mathews J, Gireud-Goss M, Saklad AR, Himali J, Beiser A, Cavazos JE, Mahaney MC, Maestre G, DeCarli C, Shipp EL, Vasan RS, Seshadri S. PMID: 37604954; PMCID: PMC10442369.
      View in: PubMed   Mentions:
    5. MISPEL: A supervised deep learning harmonization method for multi-scanner neuroimaging data. Med Image Anal. 2023 10; 89:102926. Torbati ME, Minhas DS, Laymon CM, Maillard P, Wilson JD, Chen CL, Crainiceanu CM, DeCarli CS, Hwang SJ, Tudorascu DL. PMID: 37595405.
      View in: PubMed   Mentions:
    6. Cardiovascular health and cognitive outcomes: Findings from a biracial population-based study in the United States. Alzheimers Dement. 2023 Aug 03. Dhana A, DeCarli CS, Dhana K, Desai P, Holland TM, Evans DA, Rajan KB. PMID: 37534894.
      View in: PubMed   Mentions:
    7. The complex pathway between amyloid β and cognition: implications for therapy. Lancet Neurol. 2023 Sep; 22(9):847-857. Jagust WJ, Teunissen CE, DeCarli C. PMID: 37454670.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. PMID: 37461624; PMCID: PMC10350126.
      View in: PubMed   Mentions:
    9. The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathol Commun. 2023 Jun 29; 11(1):105. Scalco R, Saito N, Beckett L, Nguyen ML, Huie E, Wang HP, Flaherty DA, Honig LS, DeCarli C, Rissman RA, Teich AF, Jin LW, Dugger BN. PMID: 37386610; PMCID: PMC10311731.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels. Commun Biol. 2023 Jun 24; 6(1):668. Wong DR, Magaki SD, Vinters HV, Yong WH, Monuki ES, Williams CK, Martini AC, DeCarli C, Khacherian C, Graff JP, Dugger BN, Keiser MJ. PMID: 37355729; PMCID: PMC10290693.
      View in: PubMed   Mentions: Translation:Humans
    11. Clinical trials in vascular cognitive impairment following SPRINT-MIND: An international perspective. Cell Rep Med. 2023 06 20; 4(6):101089. Elahi FM, Alladi S, Black SE, Claassen JAHR, DeCarli C, Hughes TM, Moonen J, Pajewski NM, Price BR, Satizabal C, Shaaban CE, Silva NCBS, Snyder HM, Sveikata L, Williamson JD, Wolters FJ, Hainsworth AH. PMID: 37343515; PMCID: PMC10314118.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function. Aging Dis. 2023 May 26. Liu X, Barisano G, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Maillard P, Satizabal CL, Fadaee E, Habes M, Stables L, Singh H, Fischl B, Kouwe AV, Schwab K, Helmer KG, Greenberg SM, Wang DJJ, MarkVCID Consortium. PMID: 37307817.
      View in: PubMed   Mentions:
    13. Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurol. 2023 Jul; 22(7):602-618. Duering M, Biessels GJ, Brodtmann A, Chen C, Cordonnier C, de Leeuw FE, Debette S, Frayne R, Jouvent E, Rost NS, Ter Telgte A, Al-Shahi Salman R, Backes WH, Bae HJ, Brown R, Chabriat H, De Luca A, deCarli C, Dewenter A, Doubal FN, Ewers M, Field TS, Ganesh A, Greenberg S, Helmer KG, Hilal S, Jochems ACC, Jokinen H, Kuijf H, Lam BYK, Lebenberg J, MacIntosh BJ, Maillard P, Mok VCT, Pantoni L, Rudilosso S, Satizabal CL, Schirmer MD, Schmidt R, Smith C, Staals J, Thrippleton MJ, van Veluw SJ, Vemuri P, Wang Y, Werring D, Zedde M, Akinyemi RO, Del Brutto OH, Markus HS, Zhu YC, Smith EE, Dichgans M, Wardlaw JM. PMID: 37236211.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment. Transl Psychiatry. 2023 04 29; 13(1):140. Granot-Hershkovitz E, Spitzer B, Yang Y, Tarraf W, Yu B, Boerwinkle E, Fornage M, Mosley TH, DeCarli C, Kristal BS, González HM, Sofer T. PMID: 37120436; PMCID: PMC10148805.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers. Stroke. 2023 05; 54(5):1227-1235. Sapkota S, Erickson K, Fletcher E, Tomaszewski Farias SE, Jin LW, DeCarli C, Alzheimer’s Disease Neuroimaging Initiative*. PMID: 37021572; PMCID: PMC10121244.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers. JAMA Netw Open. 2023 04 03; 6(4):e236431. George KM, Maillard P, Gilsanz P, Fletcher E, Peterson RL, Fong J, Mayeda ER, Mungas DM, Barnes LL, Glymour MM, DeCarli C, Whitmer RA, Whitmer RA. PMID: 37010868; PMCID: PMC10071343.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Association of Left Atrial Strain With Ischemic Stroke Risk in Older Adults. JAMA Cardiol. 2023 04 01; 8(4):317-325. Mannina C, Ito K, Jin Z, Yoshida Y, Matsumoto K, Shames S, Russo C, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Homma S, Sacco RL, Di Tullio MR. PMID: 36753086; PMCID: PMC9909576.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Interaction analysis of ancestry-enriched variants with APOE-ɛ4 on MCI in the Study of Latinos-Investigation of Neurocognitive Aging. Sci Rep. 2023 03 29; 13(1):5114. Granot-Hershkovitz E, Xia R, Yang Y, Spitzer B, Tarraf W, Vásquez PM, Lipton RB, Daviglus M, Argos M, Cai J, Kaplan R, Fornage M, DeCarli C, Gonzalez HM, Sofer T. PMID: 36991100; PMCID: PMC10060219.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Subclinical left ventricular systolic dysfunction and incident stroke in the elderly: long-term findings from Cardiovascular Abnormalities and Brain Lesions. Eur Heart J Cardiovasc Imaging. 2023 03 21; 24(4):522-531. Yoshida Y, Jin Z, Russo C, Homma S, Nakanishi K, Ito K, Mannina C, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 35900282; PMCID: PMC10226754.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Toward a statistical validation of brain signatures as robust measures of behavioral substrates. Hum Brain Mapp. 2023 06 01; 44(8):3094-3111. Fletcher E, Farias S, DeCarli C, Gavett B, Widaman K, De Leon F, Mungas D. PMID: 36939069; PMCID: PMC10171525.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts. Neurology. 2023 05 02; 100(18):e1930-e1943. Zhang Y, Liu X, Wiggins KL, Kurniansyah N, Guo X, Rodrigue AL, Zhao W, Yanek LR, Ratliff SM, Pitsillides A, Aguirre Patiño JS, Sofer T, Arking DE, Austin TR, Beiser AS, Blangero J, Boerwinkle E, Bressler J, Curran JE, Hou L, Hughes TM, Kardia SLR, Launer LJ, Levy D, Mosley TH, Nasrallah IM, Rich SS, Rotter JI, Seshadri S, Tarraf W, González KA, Ramachandran V, Yaffe K, Nyquist PA, Psaty BM, DeCarli CS, Smith JA, Glahn DC, González HM, Bis JC, Fornage M, Heckbert SR, Fitzpatrick AL, Liu C, Satizabal CL, NHLBI Trans-Omics for Precision Medicine (TOPMed) program, Mitochondrial and Neurocognitive Working . PMID: 36927883; PMCID: PMC10159770.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Inflammatory biomarkers and MRI visible perivascular spaces: The Framingham Heart Study. Neurobiol Aging. 2023 07; 127:12-22. Ekenze O, Pinheiro A, Demissie S, Charidimou A, Beiser AS, Vasan RS, Benjamin EJ, DeCarli C, Seshadri S, Romero JR. PMID: 37018882; PMCID: PMC10198814.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Assessing cognitive impairment in an ethnically diverse cohort of oldest-old: the life after 90 study. Aging Clin Exp Res. 2023 May; 35(5):979-986. Petrosyan D, Corrada MM, Kawas CH, Demoz A, Ganzon C, Popovich O, Gaied R, Mungas D, Gilsanz P, Vieira KE, Whitmer RA, Whitmer RA, DeCarli C. PMID: 36870029; PMCID: PMC10149459.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Serum neurofilament light chain, brain infarcts, and the risk of stroke: a prospective population-based cohort study. Eur J Epidemiol. 2023 Apr; 38(4):427-434. Dhana A, DeCarli C, Aggarwal NT, Dhana K, Desai P, Evans DA, Rajan KB. PMID: 36867286; PMCID: PMC10081967.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI). Neurobiol Aging. 2023 06; 126:58-66. Stickel AM, Tarraf W, González KA, Ivanovic V, Morlett Paredes A, Zeng D, Cai J, Isasi CR, Kaplan R, Lipton RB, Daviglus M, Testai FD, Lamar M, Gallo LC, Talavera GA, Gellman MD, Ramos AR, González HM, DeCarli C. PMID: 36933278; PMCID: PMC10363333.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides. J Neuropathol Exp Neurol. 2023 02 21; 82(3):212-220. Oliveira LC, Lai Z, Harvey D, Nzenkue K, Jin LW, Decarli C, Chuah CN, Dugger BN. PMID: 36692190; PMCID: PMC9941825.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2023 02 13; 146(2):492-506. Yang Y, Knol MJ, Wang R, Mishra A, Liu D, Luciano M, Teumer A, Armstrong N, Bis JC, Jhun MA, Li S, Adams HHH, Aziz NA, Bastin ME, Bourgey M, Brody JA, Frenzel S, Gottesman RF, Hosten N, Hou L, Kardia SLR, Lohner V, Marquis P, Maniega SM, Satizabal CL, Sorond FA, Valdés Hernández MC, van Duijn CM, Vernooij MW, Wittfeld K, Yang Q, Zhao W, Boerwinkle E, Levy D, Deary IJ, Jiang J, Mather KA, Mosley TH, Psaty BM, Sachdev PS, Smith JA, Sotoodehnia N, DeCarli CS, Breteler MMB, Ikram MA, Grabe HJ, Wardlaw J, Longstreth WT, Launer LJ, Seshadri S, Debette S, Fornage M. PMID: 35943854; PMCID: PMC9924914.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer's disease (AD) neuropathology: A hypothesis and review. Front Aging Neurosci. 2023; 15:1096206. Sharp FR, DeCarli CS, Jin LW, Zhan X. PMID: 36845656; PMCID: PMC9950279.
      View in: PubMed   Mentions: 3  
    29. Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985. Res Sq. 2023 Jan 30. DeCarli C, Pase M, Beiser A, Kojis D, Satizabal C, Himali J, Aparicio H, Flether E, Maillard P, Seshadri S. PMID: 36778357; PMCID: PMC9915799.
      View in: PubMed   Mentions:
    30. Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels. bioRxiv. 2023 Jan 17. Wong DR, Magaki SD, Vinters HV, Yong WH, Monuki ES, Williams CK, Martini AC, DeCarli C, Khacherian C, Graff JP, Dugger BN, Keiser MJ. PMID: 36711704; PMCID: PMC9882138.
      View in: PubMed   Mentions:
    31. Dual cognitive and mobility impairments and future dementia - Setting a research agenda. Alzheimers Dement. 2023 04; 19(4):1579-1586. Tian Q, Montero-Odasso M, Buchman AS, Mielke MM, Espinoza S, DeCarli CS, Newman AB, Kritchevsky SB, Rebok GW, Resnick SM, Thambisetty M, Verghese J, Ferrucci L. PMID: 36637077; PMCID: PMC10101877.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. TDP-43 Pathology in the Setting of Intermediate and High Alzheimer's Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups. J Alzheimers Dis. 2023; 91(4):1291-1301. Huie EZ, Escudero A, Saito N, Harvey D, Nguyen ML, Lucot KL, LaGrande J, Mungas D, DeCarli C, Lamar M, Schneider JA, Kapasi A, Rissman RA, Teich AF, Dugger BN. PMID: 36617779; PMCID: PMC9974776.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. J Alzheimers Dis. 2023; 95(2):561-572. Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS. PMID: 37574733.
      View in: PubMed   Mentions:
    34. White matter hyperintensity, neurofilament light chain, and cognitive decline. Ann Clin Transl Neurol. 2023 03; 10(3):321-327. Dhana A, DeCarli C, Dhana K, Desai P, Wilson RS, Evans DA, Rajan KB. PMID: 36542548; PMCID: PMC10014007.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    35. IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury. Cell Rep. 2022 12 20; 41(12):111848. Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, Sheth SA, Williams CK, Zhang XR, Macknicki M, Brumm A, Kawaguchi R, Mai P, Kaneko N, Vinters HV, Carmichael ST, Havton LA, DeCarli C, Hinman JD. PMID: 36543124; PMCID: PMC10026849.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
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    38. Genetic associations between sleep traits and cognitive ageing outcomes in the Hispanic Community Health Study/Study of Latinos. EBioMedicine. 2023 Jan; 87:104393. Zhang Y, Elgart M, Granot-Hershkovitz E, Wang H, Tarraf W, Ramos AR, Stickel AM, Zeng D, Garcia TP, Testai FD, Wassertheil-Smoller S, Isasi CR, Daviglus ML, Kaplan R, Fornage M, DeCarli C, Redline S, González HM, Sofer T. PMID: 36493726; PMCID: PMC9732133.
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    40. Optimizing quantification of MK6240 tau PET in unimpaired older adults. Neuroimage. 2023 01; 265:119761. Harrison TM, Ward TJ, Murphy A, Baker SL, Dominguez PA, Koeppe R, Vemuri P, Lockhart SN, Jung Y, Harvey DJ, Lovato L, Toga AW, Masdeu J, Oh H, Gitelman DR, Aggarwal N, Snyder HM, Baker LD, DeCarli C, Jagust WJ, Landau SM, U.S. POINTER Study Group. PMID: 36455762; PMCID: PMC9957642.
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    41. Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study. Front Cardiovasc Med. 2022; 9:1013876. Cooper LL, Rong J, Maillard P, Beiser A, Hamburg NM, Larson MG, DeCarli C, Vasan RS, Seshadri S, Mitchell GF. PMID: 36386360; PMCID: PMC9663798.
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    43. Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study. Neurology. 2022 Oct 05. Satizabal CL, Himali JJ, Beiser AS, Ramachandran V, Melo van Lent D, Himali D, Aparicio HJ, Maillard P, DeCarli CS, Harris W, Seshadri S. PMID: 36198518; PMCID: PMC9754651.
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    46. Progression of cerebral white matter hyperintensities is related to leucocyte gene expression. Brain. 2022 09 14; 145(9):3179-3186. Jickling GC, Ander BP, Zhan X, Stamova B, Hull H, DeCarli C, Sharp FR. PMID: 35325079; PMCID: PMC10233292.
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    48. Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study. EClinicalMedicine. 2022 Nov; 53:101643. Tao Q, Akhter-Khan SC, Ang TFA, DeCarli C, Alosco ML, Mez J, Killiany R, Devine S, Rokach A, Itchapurapu IS, Zhang X, Lunetta KL, Steffens DC, Farrer LA, Greve DN, Au R, Qiu WQ. PMID: 36105871; PMCID: PMC9465265.
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    50. Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimers Dement (Amst). 2022; 14(1):e12349. Sapkota S, Erickson K, Harvey D, Tomaszewski-Farias SE, Olichney JM, Johnson DK, Dugger BN, Mungas DM, Fletcher E, Maillard P, Seshadri S, Satizabal CL, Kautz T, Parent D, Tracy RP, Maezawa I, Jin LW, DeCarli C. PMID: 36092690; PMCID: PMC9434579.
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    53. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain. 2022 06 30; 145(6):1992-2007. Mishra A, Duplaà C, Vojinovic D, Suzuki H, Sargurupremraj M, Zilhão NR, Li S, Bartz TM, Jian X, Zhao W, Hofer E, Wittfeld K, Harris SE, van der Auwera-Palitschka S, Luciano M, Bis JC, Adams HHH, Satizabal CL, Gottesman RF, Gampawar PG, Bülow R, Weiss S, Yu M, Bastin ME, Lopez OL, Vernooij MW, Beiser AS, Völker U, Kacprowski T, Soumare A, Smith JA, Knopman DS, Morris Z, Zhu Y, Rotter JI, Dufouil C, Valdés Hernández M, Muñoz Maniega S, Lathrop M, Boerwinkle E, Schmidt R, Ihara M, Mazoyer B, Yang Q, Joutel A, Tournier-Lasserve E, Launer LJ, Deary IJ, Mosley TH, Amouyel P, DeCarli CS, Psaty BM, Tzourio C, Kardia SLR, Grabe HJ, Teumer A, van Duijn CM, Schmidt H, Wardlaw JM, Ikram MA, Fornage M, Gudnason V, Seshadri S, Matthews PM, Longstreth WT, Couffinhal T, Debette S. PMID: 35511193; PMCID: PMC9255380.
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    54. High-Density Lipoprotein Changes in Alzheimer's Disease Are APOE Genotype-Specific. Biomedicines. 2022 Jun 24; 10(7). Hong BV, Zheng J, Agus JK, Tang X, Lebrilla CB, Jin LW, Maezawa I, Erickson K, Harvey DJ, DeCarli CS, Mungas DM, Olichney JM, Farias ST, Zivkovic AM. PMID: 35884800; PMCID: PMC9312991.
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    56. BrainSec: Automated Brain Tissue Segmentation Pipeline for Scalable Neuropathological Analysis. IEEE Access. 2022; 10:49064-49079. Lai Z, Oliveira LC, Guo R, Xu W, Hu Z, Mifflin K, Decarli C, Cheung SC, Chuah CN, Dugger BN. PMID: 36157332; PMCID: PMC9503016.
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    60. Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois. JAMA Netw Open. 2022 04 01; 5(4):e227512. Dhana A, DeCarli C, Dhana K, Desai P, Krueger K, Evans DA, Rajan KB. PMID: 35426922; PMCID: PMC9012965.
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    61. Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. Alzheimers Dement (Amst). 2022; 14(1):e12261. Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ, Rosenberg GA, Snoussi H, Sepehrband F, Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Schwab K, Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL, MarkVCID Consortium. PMID: 35382232; PMCID: PMC8959640.
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    62. Examination of Neurofilament Light Chain Serum Concentrations, Physical Activity, and Cognitive Decline in Older Adults. JAMA Netw Open. 2022 03 01; 5(3):e223596. Desai P, Dhana K, DeCarli C, Wilson RS, McAninch EA, Evans DA, Rajan KB. PMID: 35315915; PMCID: PMC8941360.
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    63. Blood metabolites predicting mild cognitive impairment in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL). Alzheimers Dement (Amst). 2022; 14(1):e12259. He S, Granot-Hershkovitz E, Zhang Y, Bressler J, Tarraf W, Yu B, Huang T, Zeng D, Wassertheil-Smoller S, Lamar M, Daviglus M, Marquine MJ, Cai J, Mosley T, Kaplan R, Boerwinkle E, Fornage M, DeCarli C, Kristal B, Gonzalez HM, Sofer T. PMID: 35229015; PMCID: PMC8865745.
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    65. Measuring Cognitive Health in Ethnically Diverse Older Adults. J Gerontol B Psychol Sci Soc Sci. 2022 02 03; 77(2):261-271. Hernandez Saucedo H, Whitmer RA, Whitmer RA, Glymour M, DeCarli C, Mayeda ER, Gilsanz P, Miles SQ, Bhulani N, Tomaszewski Farias S, Olichney J, Mungas D. PMID: 33842969; PMCID: PMC8824686.
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    66. Accounting for lack of representation in dementia research: Generalizing KHANDLE study findings on the prevalence of cognitive impairment to the California older population. Alzheimers Dement. 2022 11; 18(11):2209-2217. Hayes-Larson E, Mobley TM, Mungas D, Seamans MJ, Glymour MM, Gilsanz P, DeCarli C, Whitmer RA, Whitmer RA, Mayeda ER. PMID: 35102726; PMCID: PMC9339583.
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    67. Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2022 Feb 01; 12(1):2008. Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 35105918; PMCID: PMC8807814.
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    68. Imaging Markers of Vascular Brain Health: Quantification, Clinical Implications, and Future Directions. Stroke. 2022 02; 53(2):416-426. Vemuri P, Decarli C, Duering M. PMID: 35000423; PMCID: PMC8830603.
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    69. Plasma EFEMP1 Is Associated with Brain Aging and Dementia: The Framingham Heart Study. J Alzheimers Dis. 2022; 85(4):1657-1666. McGrath ER, Himali JJ, Levy D, Yang Q, DeCarli CS, Courchesne P, Satizabal CL, Finney R, Vasan RS, Beiser AS, Seshadri S. PMID: 34958018.
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    70. Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study. J Alzheimers Dis. 2022; 86(4):1603-1609. Jacobs HIL, O'Donnell A, Satizabal CL, Lois C, Kojis D, Hanseeuw BJ, Thibault E, Sanchez JS, Buckley RF, Yang Q, DeCarli C, Killiany R, Sargurupremraj M, Sperling RA, Johnson KA, Beiser AS, Seshadri S. PMID: 35213372; PMCID: PMC9038711.
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    71. Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study. J Alzheimers Dis. 2022; 86(3):1371-1383. Weinstein G, O'Donnell A, Davis-Plourde K, Zelber-Sagi S, Ghosh S, DeCarli CS, Thibault EG, Sperling RA, Johnson KA, Beiser AS, Seshadri S. PMID: 35213373.
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    72. Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults. J Alzheimers Dis. 2022; 88(1):311-322. Wittfeld K, Raman MR, Conner SC, Aslam A, Teumer A, Nauck M, Hosten N, Habes M, DeCarli C, Vasan RS, Beiser AS, Himali JJ, Seshadri S, Grabe HJ, Satizabal CL. PMID: 35599493; PMCID: PMC9472289.
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    74. Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis. J Alzheimers Dis. 2022; 90(3):1073-1083. Frenzel S, Bis JC, Gudmundsson EF, O'Donnell A, Simino J, Yaqub A, Bartz TM, Brusselle GGO, Bülow R, DeCarli CS, Ewert R, Gharib SA, Ghosh S, Gireud-Goss M, Gottesman RF, Ikram MA, Knopman DS, Launer LJ, London SJ, Longstreth WT, Lopez OL, Melo van Lent D, O'Connor G, Satizabal CL, Shrestha S, Sigurdsson S, Stubbe B, Talluri R, Vasan RS, Vernooij MW, Völzke H, Wiggins KL, Yu B, Beiser AS, Gudnason V, Mosley T, Psaty BM, Wolters FJ, Grabe HJ, Seshadri S. PMID: 36213999; PMCID: PMC9712227.
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    75. Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias. Alzheimers Dement (Amst). 2021; 13(1):e12265. Mungas D, Shaw C, Hayes-Larson E, DeCarli C, Farias ST, Olichney J, Saucedo HH, Gilsanz P, Glymour MM, Whitmer RA, Whitmer RA, Mayeda ER. PMID: 35005198; PMCID: PMC8719430.
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    77. Multi-scanner Harmonization of Paired Neuroimaging Data via Structure Preserving Embedding Learning. IEEE Int Conf Comput Vis Workshops. 2021 Oct; 2021:3277-3286. Torbati ME, Tudorascu DL, Minhas DS, Maillard P, DeCarli CS, Hwang SJ. PMID: 34909551; PMCID: PMC8668020.
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    78. The link between blood pressure and Alzheimer's disease. Lancet Neurol. 2021 11; 20(11):878-879. DeCarli C. PMID: 34687619.
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    79. Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 06; 7(6):616-628. Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumaré A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli C, Fletcher E, Paus T, Lathrop M, Adams HHH, Bis JC, Seshadri S, Tzourio C, Mazoyer B, Debette S. PMID: 34700051; PMCID: PMC9395126.
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    80. Frontal white matter lesions in Alzheimer's disease are associated with both small vessel disease and AD-associated cortical pathology. Acta Neuropathol. 2021 12; 142(6):937-950. McAleese KE, Miah M, Graham S, Hadfield GM, Walker L, Johnson M, Colloby SJ, Thomas AJ, DeCarli C, Koss D, Attems J. PMID: 34608542; PMCID: PMC8568857.
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    81. Bone Mineral Density Measurements and Association With Brain Structure and Cognitive Function: The Framingham Offspring Cohort. Alzheimer Dis Assoc Disord. 2021 Oct-Dec 01; 35(4):291-297. Stefanidou M, O'Donnell A, Himali JJ, DeCarli C, Satizabal C, Beiser AS, Seshadri S. PMID: 33973881; PMCID: PMC8608007.
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    82. Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease. Alzheimers Dement. 2022 04; 18(4):824-857. Veitch DP, Weiner MW, Aisen PS, Beckett LA, DeCarli C, Green RC, Harvey D, Jack CR, Jagust W, Landau SM, Morris JC, Okonkwo O, Perrin RJ, Petersen RC, Rivera-Mindt M, Saykin AJ, Shaw LM, Toga AW, Tosun D, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative. PMID: 34581485; PMCID: PMC9158456.
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    83. Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort. Front Med (Lausanne). 2021; 8:671945. Lau WL, Fisher M, Fletcher E, DeCarli C, Troutt H, Corrada MM, Kawas C, Paganini-Hill A. PMID: 34616751; PMCID: PMC8488112.
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    85. Impact of Cardiovascular Risk Factors in Adolescence, Young Adulthood, and Midlife on Late-Life Cognition: Study of Healthy Aging in African Americans. J Gerontol A Biol Sci Med Sci. 2021 08 13; 76(9):1692-1698. George KM, Gilsanz P, Peterson RL, Barnes LL, DeCarli CS, Mayeda ER, Mungas DM, Whitmer RA, Whitmer RA. PMID: 34387334; PMCID: PMC8361347.
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    86. Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2021 08 10; 11(1):16198. Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 34376699; PMCID: PMC8355229.
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    87. Association of Social Support With Brain Volume and Cognition. JAMA Netw Open. 2021 08 02; 4(8):e2121122. Salinas J, O'Donnell A, Kojis DJ, Pase MP, DeCarli C, Rentz DM, Berkman LF, Beiser A, Seshadri S. PMID: 34398201; PMCID: PMC8369356.
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    88. The latent factor structure underlying regional brain volume change and its relation to cognitive change in older adults. Neuropsychology. 2021 Sep; 35(6):643-655. Gavett BE, Fletcher E, Widaman KF, Tomaszewski Farias S, DeCarli C, Mungas D. PMID: 34292026; PMCID: PMC8501944.
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    89. Prevalence of incidental brain MRI findings of clinical relevance in a diverse Hispanic/Latino population. J Neuroimaging. 2021 11; 31(6):1166-1175. Ivanovic V, Seiler S, Tarraf W, Crivello E, Martinez O, Lipton RB, Isasi CR, Copello TG, Talavera GA, Gallo LC, Lamar M, Testai F, Schneiderman N, Gellman MD, Daviglus M, Gonzalez HM, DeCarli C, Lipton ML. PMID: 34288226; PMCID: PMC10332335.
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    90. Coronary Artery Calcium Assessed Years Before Was Positively Associated With Subtle White Matter Injury of the Brain in Asymptomatic Middle-Aged Men: The Framingham Heart Study. Circ Cardiovasc Imaging. 2021 07; 14(7):e011753. Suzuki H, Davis-Plourde K, Beiser A, Kunimura A, Miura K, DeCarli C, Maillard P, Mitchell GF, Vasan RS, Seshadri S, Fujiyoshi A. PMID: 34256573; PMCID: PMC8323993.
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    91. Neighborhood racial/ethnic segregation and cognitive decline in older adults. Soc Sci Med. 2021 09; 284:114226. Meyer OL, Besser L, Mitsova D, Booker M, Luu E, Tobias M, Farias ST, Mungas D, DeCarli C, Whitmer RA, Whitmer RA. PMID: 34303293; PMCID: PMC8656323.
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    92. Digital sleep measures and white matter health in the Framingham Heart Study. Explor Med. 2021; 2(3):253-267. Thomas RJ, Kim H, Maillard P, DeCarli CS, Heckman EJ, Karjadi C, Ang TFA, Au R. PMID: 34927164; PMCID: PMC8682916.
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    93. Convolutional Neural Net Learning Can Achieve Production-Level Brain Segmentation in Structural Magnetic Resonance Imaging. Front Neurosci. 2021; 15:683426. Fletcher E, DeCarli C, Fan AP, Knaack A. PMID: 34234642; PMCID: PMC8255694.
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    94. Amyloid-PET imaging offers small improvements in predictions of future cognitive trajectories. Neuroimage Clin. 2021; 31:102713. Ackley SF, Hayes-Larson E, Brenowitz WD, Swinnerton K, Mungas D, Fletcher E, Singh B, Whitmer RA, Whitmer RA, DeCarli C, Maria Glymour M. PMID: 34153689; PMCID: PMC8233225.
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    95. Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Alzheimers Dement. 2021 10; 17(10):1663-1674. Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C, Knol MJ, Li S, Schraen S, Grove ML, Satizabal C, Amin N, Berr C, Younkin S, Alzheimer's Disease Neuroimaging Initiative, Gottesman RF, Buée L, Beiser A, Knopman DS, Uitterlinden A, DeCarli C, Bressler J, DeStefano A, Dartigues JF, Yang Q, Boerwinkle E, Tzourio C, Fornage M, Ikram MA, Amouyel P, de Jager P, Reitz C, Mosley TH, Lambert JC, Seshadri S, van Duijn CM. PMID: 34002480; PMCID: PMC8597077.
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    96. Lifecourse socioeconomic changes and late-life cognition in a cohort of U.S.-born and U.S. immigrants: findings from the KHANDLE study. BMC Public Health. 2021 05 13; 21(1):920. Peterson RL, George KM, Gilsanz P, Mayeda ER, Glymour MM, Meyer OL, Mungas DM, DeCarli C, Whitmer RA, Whitmer RA. PMID: 33985461; PMCID: PMC8120825.
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    97. A robust brain signature region approach for episodic memory performance in older adults. Brain. 2021 05 07; 144(4):1089-1102. Fletcher E, Gavett B, Crane P, Soldan A, Hohman T, Farias S, Widaman K, Groot C, Renteria MA, Zahodne L, DeCarli C, Mungas D, Alzheimer's Disease Neuroimaging Initiative. PMID: 33895818; PMCID: PMC8105039.
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    98. Racial/Ethnic Disparities in Young Adulthood and Midlife Cardiovascular Risk Factors and Late-life Cognitive Domains: The Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study. Alzheimer Dis Assoc Disord. 2021 Apr-Jun 01; 35(2):99-105. Peterson RL, George KM, Gilsanz P, Ackley S, Mayeda ER, Glymour MM, Mungas DM, DeCarli C, Whitmer RA, Whitmer RA. PMID: 34006727; PMCID: PMC8862715.
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    99. Cortical superficial siderosis in the general population: The Framingham Heart and Rotterdam studies. Int J Stroke. 2021 10; 16(7):798-808. Shoamanesh A, Akoudad S, Himali JJ, Beiser AS, DeCarli C, Seshadri S, Arfan Ikram M, Romero JR, Vernooij MW. PMID: 33478376.
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    100. MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols. Alzheimers Dement. 2021 04; 17(4):716-725. Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM, MarkVCID Consortium. PMID: 33480157; PMCID: PMC8627001.
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    101. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Sci Transl Med. 2021 01 20; 13(577). Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gómez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA. PMID: 33472953; PMCID: PMC7978042.
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    102. Race/Ethnic Disparities in Mild Cognitive Impairment and Dementia: The Northern Manhattan Study. J Alzheimers Dis. 2021; 80(3):1129-1138. Wright CB, DeRosa JT, Moon MP, Strobino K, DeCarli C, Cheung YK, Assuras S, Levin B, Stern Y, Sun X, Rundek T, Elkind MSV, Sacco RL. PMID: 33646162; PMCID: PMC8150441.
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    103. Mind Diet Adherence and Cognitive Performance in the Framingham Heart Study. J Alzheimers Dis. 2021; 82(2):827-839. Melo van Lent D, O'Donnell A, Beiser AS, Vasan RS, DeCarli CS, Scarmeas N, Wagner M, Jacques PF, Seshadri S, Himali JJ, Pase MP. PMID: 34092629.
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    104. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 01 01; 78(1):102-113. Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Writing Group for the Alzheimer’s Disease Genetics Consortium (ADGC), Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. PMID: 33074286; PMCID: PMC7573798.
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    105. Slow-Wave Sleep and MRI Markers of Brain Aging in a Community-Based Sample. Neurology. 2021 03 09; 96(10):e1462-e1469. Baril AA, Beiser AS, Mysliwiec V, Sanchez E, DeCarli CS, Redline S, Gottlieb DJ, Maillard P, Romero JR, Satizabal CL, Zucker JM, Seshadri S, Pase MP, Himali JJ. PMID: 33361258; PMCID: PMC8055313.
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    106. Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020 12 08; 11(1):6285. Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Trégouët DA, International Network against Thrombosis (INVENT) Consortium, International Headache Genomics Consortium (IHGC), Ikram MA, Wen W, DeCarli C, Srikanth VK, Jukema JW, Slagboom EP, Kardia SLR, Okada Y, Mazoyer B, Wardlaw JM, Nyquist PA, Mather KA, Grabe HJ, Schmidt H, Van Duijn CM, Gudnason V, Longstreth WT, Launer LJ, Lathrop M, Seshadri S, Tzourio C, Adams HH, Matthews PM, Fornage M, Debette S. PMID: 33293549; PMCID: PMC7722866.
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    107. Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia. Ann Neurol. 2021 02; 89(2):389-401. Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, Spina S, Grinberg LT, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 33219525; PMCID: PMC7856004.
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    108. APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL). Alzheimers Dement. 2021 03; 17(3):466-474. Granot-Hershkovitz E, Tarraf W, Kurniansyah N, Daviglus M, Isasi CR, Kaplan R, Lamar M, Perreira KM, Wassertheil-Smoller S, Stickel A, Thyagarajan B, Zeng D, Fornage M, DeCarli CS, González HM, Sofer T. PMID: 33155766; PMCID: PMC8016734.
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    109. Left Atrial Strain and Subclinical Cerebrovascular Disease in Older Adults. JACC Cardiovasc Imaging. 2021 02; 14(2):508-510. Mannina C, Tugcu A, Jin Z, Russo C, Matsumoto K, Ito K, Homma S, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 33011124; PMCID: PMC8842543.
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    110. Remote Blood Biomarkers of Longitudinal Cognitive Outcomes in a Population Study. Ann Neurol. 2020 12; 88(6):1065-1076. Rajan KB, Aggarwal NT, McAninch EA, Weuve J, Barnes LL, Wilson RS, DeCarli C, Evans DA. PMID: 32799383; PMCID: PMC9186023.
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    111. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nat Commun. 2020 09 22; 11(1):4796. Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE, ENIGMA consortium, Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT, Fornage M, Paus T, Debette S, Ikram MA, Schmidt H, Schmidt R, Seshadri S. PMID: 32963231; PMCID: PMC7508833.
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    112. Growth Differentiation Factor 15 and NT-proBNP as Blood-Based Markers of Vascular Brain Injury and Dementia. J Am Heart Assoc. 2020 10 20; 9(19):e014659. McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. PMID: 32921207; PMCID: PMC7792414.
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    113. Association between APOE ε2 and Aβ burden in patients with Alzheimer- and vascular-type cognitive impairment. Neurology. 2020 10 27; 95(17):e2354-e2365. Lee JS, Lee H, Park S, Choe Y, Park YH, Cheon BK, Hahn A, Ossenkoppele R, Kim HJ, Kim S, Yoo H, Jang H, Cho SH, Kim SJ, Kim JP, Jung YH, Park KC, DeCarli C, Weiner MW, Na DL, Seo SW. PMID: 32928967; PMCID: PMC7682916.
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    114. Association of common genetic variants with brain microbleeds: A genome-wide association study. Neurology. 2020 12 15; 95(24):e3331-e3343. Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS, Alzheimer's Disease Neuroimaging Initiative. PMID: 32913026; PMCID: PMC7836652.
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    115. Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study. Hypertension. 2020 09; 76(3):707-714. Petrea RE, O'Donnell A, Beiser AS, Habes M, Aparicio H, DeCarli C, Seshadri S, Romero JR. PMID: 32755403; PMCID: PMC7577565.
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    116. Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory. Neurology. 2020 11 10; 95(19):e2622-e2634. Han JW, Maillard P, Harvey D, Fletcher E, Martinez O, Johnson DK, Olichney JM, Farias ST, Villeneuve S, Jagust W, Mungas D, DeCarli C. PMID: 32732300; PMCID: PMC7713731.
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    117. Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos. Transl Psychiatry. 2020 07 22; 10(1):245. Jian X, Sofer T, Tarraf W, Bressler J, Faul JD, Zhao W, Ratliff SM, Lamar M, Launer LJ, Laurie CC, Schneiderman N, Weir DR, Wright CB, Yaffe K, Zeng D, DeCarli C, Mosley TH, Smith JA, González HM, Fornage M. PMID: 32699239; PMCID: PMC7376098.
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    118. Cognitive reserve and midlife vascular risk: Cognitive and clinical outcomes. Ann Clin Transl Neurol. 2020 08; 7(8):1307-1317. Soldan A, Pettigrew C, Zhu Y, Wang MC, Gottesman RF, DeCarli C, Albert M, BIOCARD Research Team. PMID: 32856790; PMCID: PMC7448143.
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    119. Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study. Ann Clin Transl Neurol. 2020 07; 7(7):1083-1091. Romero JR, Demissie S, Beiser A, Himali JJ, DeCarli C, Levy D, Seshadri S. PMID: 32588552; PMCID: PMC7359126.
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    120. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke. 2020 07; 51(7):2111-2121. Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA. PMID: 32517579; PMCID: PMC7365038.
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    121. Flavonoid Intake and MRI Markers of Brain Health in the Framingham Offspring Cohort. J Nutr. 2020 06 01; 150(6):1545-1553. Shishtar E, Rogers GT, Blumberg JB, Au R, DeCarli C, Jacques PF. PMID: 32211795; PMCID: PMC7269753.
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    122. The progression of carotid atherosclerosis and imaging markers of dementia. Alzheimers Dement (N Y). 2020; 6(1):e12015. Baradaran H, Demissie S, Himali JJ, Beiser A, Gupta A, Polak JF, DeCarli C, Seshadri S, Romero JR. PMID: 32296732; PMCID: PMC7154591.
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    128. Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease. Alzheimers Dement. 2020 04; 16(4):681-695. Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH. PMID: 31879236; PMCID: PMC7138729.
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    129. Association Between Leptin, Cognition, and Structural Brain Measures Among "Early" Middle-Aged Adults: Results from the Framingham Heart Study Third Generation Cohort. J Alzheimers Dis. 2020; 77(3):1279-1289. Sanborn V, Preis SR, Ang A, Devine S, Mez J, DeCarli C, Au R, Alosco ML, Gunstad J. PMID: 32831199; PMCID: PMC7923949.
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    130. The Impact of Amyloid-β or Tau on Cognitive Change in the Presence of Severe Cerebrovascular Disease. J Alzheimers Dis. 2020; 78(2):573-585. Jang H, Kim HJ, Choe YS, Kim SJ, Park S, Kim Y, Kim KW, Lyoo CH, Cho H, Ryu YH, Choi JY, DeCarli C, Na DL, Seo SW, Alzheimer’s Disease Neuroimaging Initiative. PMID: 33016911.
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    131. White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease. Neurology. 2020 03 03; 94(9):e950-e960. Soldan A, Pettigrew C, Zhu Y, Wang MC, Moghekar A, Gottesman RF, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M, BIOCARD Research Team. PMID: 31888969; PMCID: PMC7238945.
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    132. Association Between Central Blood Pressure and Subclinical Cerebrovascular Disease in Older Adults. Hypertension. 2020 02; 75(2):580-587. Matsumoto K, Jin Z, Homma S, Elkind MSV, Rundek T, Mannina C, Lee TC, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 31865782; PMCID: PMC7008935.
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    133. Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals. Neurobiol Aging. 2020 04; 88:33-41. Pettigrew C, Soldan A, Zhu Y, Cai Q, Wang MC, Moghekar A, Miller MI, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M. PMID: 31932050; PMCID: PMC7160864.
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    134. Association of CD14 with incident dementia and markers of brain aging and injury. Neurology. 2020 01 21; 94(3):e254-e266. Pase MP, Himali JJ, Beiser AS, DeCarli C, McGrath ER, Satizabal CL, Aparicio HJ, Adams HHH, Reiner AP, Longstreth WT, Fornage M, Tracy RP, Lopez O, Psaty BM, Levy D, Seshadri S, Bis JC. PMID: 31818907; PMCID: PMC7108812.
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    137. Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways. Sci Rep. 2019 10 10; 9(1):14498. Horgusluoglu-Moloch E, Risacher SL, Crane PK, Hibar D, Thompson PM, Saykin AJ, Nho K, Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 31601890; PMCID: PMC6787090.
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    138. Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders. Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):327-330. Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, Bennett DA, Gearing M, Juncos JL, Kramer J, Lee SE, Yokoyama JS, Mendez MF, Chui H, Zarow C, Ringman JM, Kilic U, Babacan-Yildiz G, Levey A, DeCarli CS, Cotman CW, Boxer AL, Miller BL, Coppola G. PMID: 31513029; PMCID: PMC7050643.
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    139. Multimodal Hippocampal Subfield Grading For Alzheimer's Disease Classification. Sci Rep. 2019 09 25; 9(1):13845. Hett K, Ta VT, Catheline G, Tourdias T, Manjón JV, Coupé P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31554909; PMCID: PMC6761169.
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    142. Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults. JAMA Netw Open. 2019 08 02; 2(8):e199826. Zhu H, Tao Q, Ang TFA, Massaro J, Gan Q, Salim S, Zhu RY, Kolachalama VB, Zhang X, Devine S, Auerbach SH, DeCarli C, Au R, Qiu WQ. PMID: 31433485; PMCID: PMC6707010.
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    148. Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes. J Am Heart Assoc. 2019 07 16; 8(14):e012141. Vasan RS, Short MI, Niiranen TJ, Xanthakis V, DeCarli C, Cheng S, Seshadri S, Mitchell GF. PMID: 31303106; PMCID: PMC6662123.
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    149. Relationship of Cancer to Brain Aging Markers of Alzheimer's Disease: The Framingham Heart Study. Adv Geriatr Med Res. 2019; 1. Gupta A, Preis SR, Beiser AS, Splansky GL, DeCarli CS, Au R, Driver JA. PMID: 31355371; PMCID: PMC6659723.
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    150. Night-time systolic blood pressure and subclinical cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Eur Heart J Cardiovasc Imaging. 2019 Jul 01; 20(7):765-771. Nakanishi K, Jin Z, Homma S, Elkind MSV, Rundek T, Schwartz JE, Lee TC, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 30649236; PMCID: PMC6587117.
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    151. White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study. J Am Geriatr Soc. 2019 09; 67(9):1827-1834. Legdeur N, Visser PJ, Woodworth DC, Muller M, Fletcher E, Maillard P, Scheltens P, DeCarli C, Kawas CH, Corrada MM. PMID: 31169919; PMCID: PMC6732042.
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    152. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2019 08; 138(2):237-250. van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Co, IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. PMID: 31131421; PMCID: PMC6660501.
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    153. Interpretable classification of Alzheimer's disease pathologies with a convolutional neural network pipeline. Nat Commun. 2019 05 15; 10(1):2173. Tang Z, Chuang KV, DeCarli C, Jin LW, Beckett L, Keiser MJ, Dugger BN. PMID: 31092819; PMCID: PMC6520374.
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    154. Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes. JAMA Neurol. 2019 05 01; 76(5):598-606. Pase MP, Beiser AS, Himali JJ, Satizabal CL, Aparicio HJ, DeCarli C, Chêne G, Dufouil C, Seshadri S. PMID: 30830207; PMCID: PMC6515589.
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    155. Cardiovascular disease risk factor burden and cognition: Implications of ethnic diversity within the Hispanic Community Health Study/Study of Latinos. PLoS One. 2019; 14(4):e0215378. Lamar M, Durazo-Arvizu RA, Sachdeva S, Pirzada A, Perreira KM, Rundek T, Gallo LC, Grober E, DeCarli C, Lipton RB, Tarraf W, González HM, Daviglus ML. PMID: 31009492; PMCID: PMC6476505.
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    156. The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. Nat Commun. 2019 04 16; 10(1):1766. Franzmeier N, Rubinski A, Neitzel J, Ewers M, Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 30992433; PMCID: PMC6467911.
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    157. Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. JAMA Netw Open. 2019 04 05; 2(4):e192745. Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S. PMID: 31002329; PMCID: PMC6481600.
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    158. Cerebral white matter free water: A sensitive biomarker of cognition and function. Neurology. 2019 05 07; 92(19):e2221-e2231. Maillard P, Fletcher E, Singh B, Martinez O, Johnson DK, Olichney JM, Farias ST, DeCarli C. PMID: 30952798; PMCID: PMC6537135.
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    159. Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings. Alzheimers Dement (Amst). 2019 Dec; 11:286-290. Adams HHH, Roshchupkin GV, DeCarli C, Franke B, Grabe HJ, Habes M, Jahanshad N, Medland SE, Niessen W, Satizabal CL, Schmidt R, Seshadri S, Teumer A, Thompson PM, Vernooij MW, Wittfeld K, Ikram MA. PMID: 30976649; PMCID: PMC6441785.
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    160. Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia. Neurology. 2019 03 26; 92(13):631-634. Bissig D, DeCarli CS. PMID: 30910941; PMCID: PMC6453772.
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    161. A blood-based signature of cerebrospinal fluid Aβ1-42 status. Sci Rep. 2019 03 11; 9(1):4163. Goudey B, Fung BJ, Schieber C, Faux NG, Alzheimer’s Disease Metabolomics Consortium, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30853713; PMCID: PMC6409361.
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    162. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430. Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, et al. PMID: 30820047; PMCID: PMC6463297.
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    163. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimers Dement (Amst). 2019 Dec; 11:191-204. Smith EE, Biessels GJ, De Guio F, de Leeuw FE, Duchesne S, Düring M, Frayne R, Ikram MA, Jouvent E, MacIntosh BJ, Thrippleton MJ, Vernooij MW, Adams H, Backes WH, Ballerini L, Black SE, Chen C, Corriveau R, DeCarli C, Greenberg SM, Gurol ME, Ingrisch M, Job D, Lam BYK, Launer LJ, Linn J, McCreary CR, Mok VCT, Pantoni L, Pike GB, Ramirez J, Reijmer YD, Romero JR, Ropele S, Rost NS, Sachdev PS, Scott CJM, Seshadri S, Sharma M, Sourbron S, Steketee RME, Swartz RH, van Oostenbrugge R, van Osch M, van Rooden S, Viswanathan A, Werring D, Dichgans M, Wardlaw JM. PMID: 30859119; PMCID: PMC6396326.
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    164. Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics. Sci Rep. 2019 02 19; 9(1):2235. Varatharajah Y, Ramanan VK, Iyer R, Vemuri P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30783207; PMCID: PMC6381141.
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    165. Predicting Alzheimer's disease progression using multi-modal deep learning approach. Sci Rep. 2019 02 13; 9(1):1952. Lee G, Nho K, Kang B, Sohn KA, Kim D, for Alzheimer’s Disease Neuroimaging Initiative. PMID: 30760848; PMCID: PMC6374429.
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    166. Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis. Neurology. 2019 03 05; 92(10):e1086-e1097. Yakushiji Y, Wilson D, Ambler G, Charidimou A, Beiser A, van Buchem MA, DeCarli C, Ding D, Gudnason V, Hara H, Imaizumi T, Kohara K, Kwon HM, Launer LJ, Mok V, Phan T, Preis SR, Romero JR, Seshadri S, Srikanth V, Takashima Y, Tsushima Y, Wang Z, Wolf PA, Xiong Y, Yamaguchi S, Werring DJ. PMID: 30709966; PMCID: PMC6442016.
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    167. Extravascular fibrinogen in the white matter of Alzheimer's disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer's disease. Brain Pathol. 2019 05; 29(3):414-424. McAleese KE, Graham S, Dey M, Walker L, Erskine D, Johnson M, Johnston E, Thomas AJ, McKeith IG, DeCarli C, Attems J. PMID: 30485582; PMCID: PMC8028661.
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    168. Type 2 diabetes mellitus, brain atrophy, and cognitive decline. Neurology. 2019 02 19; 92(8):e823-e830. Moran C, Beare R, Wang W, Callisaya M, Srikanth V, Alzheimer's Disease Neuroimaging Initiative (ADNI). PMID: 30674592; PMCID: PMC7987953.
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    169. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 16. Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT, Debette S, Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alz. PMID: 30651383; PMCID: PMC6369905.
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    170. Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury. J Alzheimers Dis. 2019; 68(1):187-196. DeCarli C, Villeneuve S, Maillard P, Harvey D, Singh B, Carmichael O, Fletcher E, Olichney J, Farias S, Jagust W, Reed B, Mungas D. PMID: 30775991; PMCID: PMC6615551.
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    171. Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts. J Alzheimers Dis. 2019; 68(1):357-365. Conner SC, Benayoun L, Himali JJ, Adams SL, Yang Q, DeCarli C, Blusztajn JK, Beiser A, Seshadri S, Delalle I. PMID: 30775993; PMCID: PMC6481535.
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    172. Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer's Disease Center. J Alzheimers Dis. 2019; 68(1):145-158. Filshtein TJ, Dugger BN, Jin LW, Olichney JM, Farias ST, Carvajal-Carmona L, Lott P, Mungas D, Reed B, Beckett LA, DeCarli C. PMID: 30775996; PMCID: PMC7286069.
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    173. Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members. Alzheimer Dis Assoc Disord. 2019 Jan-Mar; 33(1):1-6. Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas D, DeCarli CS, Whitmer RA, Whitmer RA. PMID: 30106754; PMCID: PMC6374212.
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    174. "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders. Front Aging Neurosci. 2018; 10:343. Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH. PMID: 30483114; PMCID: PMC6244607.
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    175. Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia. Mol Neurobiol. 2019 Jul; 56(7):4916-4924. Schilling LP, Pascoal TA, Zimmer ER, Mathotaarachchi S, Shin M, de Mello Rieder CR, Gauthier S, Palmini A, Rosa-Neto P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30414086.
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    176. Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study. Neurology. 2018 11 20; 91(21):e1961-e1970. Echouffo-Tcheugui JB, Conner SC, Himali JJ, Maillard P, DeCarli CS, Beiser AS, Vasan RS, Seshadri S. PMID: 30355700; PMCID: PMC6260201.
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    177. A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants. Neuroimage Clin. 2019; 21:101581. Khlif MS, Egorova N, Werden E, Redolfi A, Boccardi M, DeCarli CS, Fletcher E, Singh B, Li Q, Bird L, Brodtmann A. PMID: 30606656; PMCID: PMC6411582.
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    178. Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology. Alzheimers Dement. 2019 02; 15(2):205-216. La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD. PMID: 30347188; PMCID: PMC6368897.
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    179. Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference. Nat Commun. 2018 10 15; 9(1):4273. Young AL, Marinescu RV, Oxtoby NP, Bocchetta M, Yong K, Firth NC, Cash DM, Thomas DL, Dick KM, Cardoso J, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R, Finger E, de Mendonça A, Sorbi S, Warren JD, Crutch S, Fox NC, Ourselin S, Schott JM, Rohrer JD, Alexander DC, Genetic FTD Initiative (GENFI), Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 30323170; PMCID: PMC6189176.
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    180. Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study. PLoS One. 2018; 13(10):e0203774. Hunter MD, Park Moon Y, DeCarli C, Gutierrez J, Wright CB, Di Tullio MR, Sacco RL, Kamel H, Elkind MSV. PMID: 30312297; PMCID: PMC6193576.
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    181. Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers. JAMA Netw Open. 2018 10 05; 1(6):e183597. Tao Q, Ang TFA, DeCarli C, Auerbach SH, Devine S, Stein TD, Zhang X, Massaro J, Au R, Qiu WQ. PMID: 30646251; PMCID: PMC6324596.
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    182. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 09 26; 9(1):3945. Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. PMID: 30258056; PMCID: PMC6158214.
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    183. Vascular risk at younger ages most strongly associates with current and future brain volume. Neurology. 2018 10 16; 91(16):e1479-e1486. Pase MP, Davis-Plourde K, Himali JJ, Satizabal CL, Aparicio H, Seshadri S, Beiser AS, DeCarli C. PMID: 30232248; PMCID: PMC6202941.
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    184. Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer's disease. Sci Rep. 2018 09 14; 8(1):13807. Huang SY, Hsu JL, Lin KJ, Liu HL, Wey SP, Hsiao IT, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30218083; PMCID: PMC6138637.
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    185. Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. Stroke. 2018 09; 49(9):2227-2229. Raman MR, Himali JJ, Conner SC, DeCarli C, Vasan RS, Beiser AS, Seshadri S, Maillard P, Satizabal CL. PMID: 30354979; PMCID: PMC6101979.
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    186. Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition. Neurobiol Aging. 2018 12; 72:14-22. Seiler S, Fletcher E, Hassan-Ali K, Weinstein M, Beiser A, Himali JJ, Satizabal CL, Seshadri S, DeCarli C, Maillard P. PMID: 30172922; PMCID: PMC6242702.
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    187. Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging. JAMA Neurol. 2018 08 01; 75(8):999-1007. Kim HJ, Park S, Cho H, Jang YK, San Lee J, Jang H, Kim Y, Kim KW, Ryu YH, Choi JY, Moon SH, Weiner MW, Jagust WJ, Rabinovici GD, DeCarli C, Lyoo CH, Na DL, Seo SW. PMID: 29799981; PMCID: PMC6142932.
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    188. Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke. 2018 08; 49(8):1812-1819. Jian X, Satizabal CL, Smith AV, Wittfeld K, Bis JC, Smith JA, Hsu FC, Nho K, Hofer E, Hagenaars SP, Nyquist PA, Mishra A, Adams HHH, Li S, Teumer A, Zhao W, Freedman BI, Saba Y, Yanek LR, Chauhan G, van Buchem MA, Cushman M, Royle NA, Bryan RN, Niessen WJ, Windham BG, DeStefano AL, Habes M, Heckbert SR, Palmer ND, Lewis CE, Eiriksdottir G, Maillard P, Mathias RA, Homuth G, Valdés-Hernández MDC, Divers J, Beiser AS, Langner S, Rice KM, Bastin ME, Yang Q, Maldjian JA, Starr JM, Sidney S, Risacher SL, Uitterlinden AG, Gudnason VG, Nauck M, Rotter JI, Schreiner PJ, Boerwinkle E, van Duijn CM, Mazoyer B, von Sarnowski B, Gottesman RF, Levy D, Sigurdsson S, Vernooij MW, Turner ST, Schmidt R, Wardlaw JM, Psaty BM, Mosley TH, DeCarli CS, Saykin AJ, Bowden DW, Becker DM, Deary IJ, Schmidt H, Kardia SLR, Ikram MA, Debette S, Grabe HJ, Longstreth WT, Seshadri S, Launer LJ, Fornage M, neuroCHARGE Working Group. PMID: 30002152; PMCID: PMC6202149.
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    189. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. JAMA Neurol. 2018 08 01; 75(8):989-998. Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL, Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative. PMID: 29801024; PMCID: PMC6142927.
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    190. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872. Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. PMID: 29967939; PMCID: PMC6280657.
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    191. Cortical tau pathology: a major player in fibre-specific white matter reductions in Alzheimer's disease? Brain. 2018 06 01; 141(6):e44. McAleese KE, Walker L, Colloby SJ, Taylor JP, Thomas AJ, DeCarli C, Attems J. PMID: 29668888.
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    192. Greater depressive symptoms, cognition, and markers of brain aging: Northern Manhattan Study. Neurology. 2018 06 05; 90(23):e2077-e2085. Zeki Al Hazzouri A, Caunca MR, Nobrega JC, Elfassy T, Cheung YK, Alperin N, Dong C, Elkind MSV, Sacco RL, DeCarli C, Wright CB. PMID: 29743209; PMCID: PMC5993180.
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    193. Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses. Alzheimers Dement (Amst). 2018; 10:382-393. Fletcher E, Filshtein TJ, Harvey D, Renaud A, Mungas D, DeCarli C. PMID: 29984299; PMCID: PMC6031152.
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    194. Ethnoracial differences in brain structure change and cognitive change. Neuropsychology. 2018 07; 32(5):529-540. Gavett BE, Fletcher E, Harvey D, Farias ST, Olichney J, Beckett L, DeCarli C, Mungas D. PMID: 29648842; PMCID: PMC6023745.
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    195. Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve. Neurobiol Aging. 2018 08; 68:142-150. Mungas D, Gavett B, Fletcher E, Farias ST, DeCarli C, Reed B. PMID: 29798764; PMCID: PMC5993638.
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    196. Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images. Sci Rep. 2018 04 09; 8(1):5697. Lu D, Popuri K, Ding GW, Balachandar R, Beg MF, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29632364; PMCID: PMC5890270.
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    197. Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states. Sci Rep. 2018 03 07; 8(1):4103. Mahjoub I, Mahjoub MA, Rekik I, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29515158; PMCID: PMC5841319.
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    198. Brain volume change and cognitive trajectories in aging. Neuropsychology. 2018 05; 32(4):436-449. Fletcher E, Gavett B, Harvey D, Farias ST, Olichney J, Beckett L, DeCarli C, Mungas D. PMID: 29494196; PMCID: PMC6525569.
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    199. A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis. 2018; 63(4):1347-1360. Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. PMID: 29843242; PMCID: PMC6081639.
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    200. Baseline White Matter Hyperintensities and Hippocampal Volume are Associated With Conversion From Normal Cognition to Mild Cognitive Impairment in the Framingham Offspring Study. Alzheimer Dis Assoc Disord. 2018 Jan-Mar; 32(1):50-56. Bangen KJ, Preis SR, Delano-Wood L, Wolf PA, Libon DJ, Bondi MW, Au R, DeCarli C, Brickman AM. PMID: 28984639; PMCID: PMC5821543.
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    201. Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-aged Adults in the Framingham Study. JAMA Neurol. 2018 01 01; 75(1):97-104. Weinstein G, Zelber-Sagi S, Preis SR, Beiser AS, DeCarli C, Speliotes EK, Satizabal CL, Vasan RS, Seshadri S. PMID: 29159396; PMCID: PMC5833484.
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    202. Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly. Stroke. 2018 02; 49(2):319-324. Nakanishi K, Jin Z, Homma S, Elkind MSV, Rundek T, Lee SC, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 29284731; PMCID: PMC5870891.
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    203. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. 2018 01 16; 90(3):e188-e196. Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Neurocognitive Working Group. PMID: 29282330; PMCID: PMC5772158.
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    204. Stroke: 'Brain health': what is it, what can we do about it and when should we start? Nat Rev Neurol. 2018 Jan; 14(1):6-8. DeCarli C. PMID: 29192257.
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    205. Validation of T1w-based segmentations of white matter hyperintensity volumes in large-scale datasets of aging. Hum Brain Mapp. 2018 03; 39(3):1093-1107. Dadar M, Maranzano J, Ducharme S, Carmichael OT, Decarli C, Collins DL, Alzheimer's Disease Neuroimaging Initiative. PMID: 29181872; PMCID: PMC6866430.
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    206. Blood pressure from mid- to late life and risk of incident dementia. Neurology. 2017 Dec 12; 89(24):2447-2454. McGrath ER, Beiser AS, DeCarli C, Plourde KL, Vasan RS, Greenberg SM, Seshadri S. PMID: 29117954; PMCID: PMC5729797.
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    207. Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty. Sci Rep. 2017 10 25; 7(1):14052. Du L, Liu K, Yao X, Yan J, Risacher SL, Han J, Guo L, Saykin AJ, Shen L, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29070790; PMCID: PMC5656688.
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    208. Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement. 2018 03; 14(3):280-292. Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG. PMID: 29055812.
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    209. Female sex, early-onset hypertension, and risk of dementia. Neurology. 2017 Oct 31; 89(18):1886-1893. Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas DM, DeCarli C, Dean A, Whitmer RA, Whitmer RA. PMID: 28978656; PMCID: PMC5664296.
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    210. Author response: Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology. 2017 10 03; 89(14):1533. Pase MP, Westwood AJ, Beiser A, Jain N, DeCarli C, Himali JJ, Auerbach SH, Seshadri S. PMID: 28972111.
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    211. Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Neurol Genet. 2017 Oct; 3(5):e185. Beecham A, Dong C, Wright CB, Dueker N, Brickman AM, Wang L, DeCarli C, Blanton SH, Rundek T, Mayeux R, Sacco RL. PMID: 28975155; PMCID: PMC5619914.
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    212. Subclinical Cerebrovascular Disease Increases the Risk of Incident Stroke and Mortality: The Northern Manhattan Study. J Am Heart Assoc. 2017 Aug 28; 6(9). Wright CB, Dong C, Perez EJ, De Rosa J, Yoshita M, Rundek T, DeCarli C, Gutierrez J, Elkind MSV, Sacco RL. PMID: 28847914; PMCID: PMC5634244.
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    213. Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults. J Am Heart Assoc. 2017 Aug 17; 6(8). Cooper LL, Himali JJ, Torjesen A, Tsao CW, Beiser A, Hamburg NM, DeCarli C, Vasan RS, Seshadri S, Pase MP, Mitchell GF. PMID: 28862943; PMCID: PMC5586458.
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    214. Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features. Sci Rep. 2017 08 15; 7(1):8137. Singanamalli A, Wang H, Madabhushi A, Alzheimer’s Disease Neuroimaging Initiative. PMID: 28811553; PMCID: PMC5558022.
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    215. Low-frequency oscillations in default mode subnetworks are associated with episodic memory impairments in Alzheimer's disease. Neurobiol Aging. 2017 11; 59:98-106. Veldsman M, Egorova N, Singh B, Mungas D, DeCarli C, Brodtmann A. PMID: 28866021.
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    216. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, et al. PMID: 28714976; PMCID: PMC5669039.
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    219. Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease. Acta Neuropathol. 2017 Sep; 134(3):459-473. McAleese KE, Walker L, Graham S, Moya ELJ, Johnson M, Erskine D, Colloby SJ, Dey M, Martin-Ruiz C, Taylor JP, Thomas AJ, McKeith IG, De Carli C, Attems J. PMID: 28638989; PMCID: PMC5563333.
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    220. Triglycerides are negatively correlated with cognitive function in nondemented aging adults. Neuropsychology. 2017 Sep; 31(6):682-688. Parthasarathy V, Frazier DT, Bettcher BM, Jastrzab L, Chao L, Chao L, Reed B, Mungas D, Weiner M, DeCarli C, Chui H, Kramer JH. PMID: 28604016; PMCID: PMC5726405.
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    221. Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary Report. Alzheimers Dement (N Y). 2017 06; 3(2):177-188. Weiner MW, Harvey D, Hayes J, Landau SM, Aisen PS, Petersen RC, Tosun D, Veitch DP, Jack CR, Decarli C, Saykin AJ, Grafman J, Neylan TC, Department of Defense Alzheimer's Disease Neuroimaging Initiative. PMID: 28758146; PMCID: PMC5526098.
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    223. Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions. Front Aging Neurosci. 2017; 9:132. Kern KC, Wright CB, Bergfield KL, Fitzhugh MC, Chen K, Moeller JR, Nabizadeh N, Elkind MSV, Sacco RL, Stern Y, DeCarli CS, Alexander GE. PMID: 28555103; PMCID: PMC5430031.
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    225. Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. Stroke. 2017 06; 48(6):1567-1573. Maillard P, Mitchell GF, Himali JJ, Beiser A, Fletcher E, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. PMID: 28473633; PMCID: PMC5502744.
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    226. Relationship between carotid arterial properties and cerebral white matter hyperintensities. Neurology. 2017 May 23; 88(21):2036-2042. Rundek T, Della-Morte D, Gardener H, Dong C, Markert MS, Gutierrez J, Roberts E, Elkind MSV, DeCarli C, Sacco RL, Wright CB. PMID: 28446647; PMCID: PMC5440241.
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    227. Age-related white matter integrity differences in oldest-old without dementia. Neurobiol Aging. 2017 08; 56:108-114. Bennett IJ, Greenia DE, Maillard P, Sajjadi SA, DeCarli C, Corrada MM, Kawas CH. PMID: 28527525; PMCID: PMC5647141.
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    228. Validation of a Regression Technique for Segmentation of White Matter Hyperintensities in Alzheimer's Disease. IEEE Trans Med Imaging. 2017 08; 36(8):1758-1768. Dadar M, Pascoal TA, Manitsirikul S, Misquitta K, Fonov VS, Tartaglia MC, Breitner J, Rosa-Neto P, Carmichael OT, Decarli C, Collins DL. PMID: 28422655.
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    229. Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study. Neurobiol Aging. 2017 06; 54:94-99. Romero JR, Beiser A, Himali JJ, Shoamanesh A, DeCarli C, Seshadri S. PMID: 28347929; PMCID: PMC5401784.
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    230. Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement. 2017 Sep; 13(9):955-964. Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S. PMID: 28274718; PMCID: PMC6820519.
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    231. Medicare Expenditure Correlates of Atrophy and Cerebrovascular Disease in Older Adults. Exp Aging Res. 2017 Mar-Apr; 43(2):149-160. Last BS, García Rubio MJ, Zhu CW, Cosentino S, Manly JJ, DeCarli C, Stern Y, Brickman AM. PMID: 28230421; PMCID: PMC5635423.
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    232. Strategies for enhancing research in aging health disparities by mentoring diverse investigators. J Clin Transl Sci. 2017 Jun; 1(3):167-175. Harawa NT, Manson SM, Mangione CM, Penner LA, Norris KC, DeCarli C, Scarinci IC, Zissimopoulos J, Buchwald DS, Hinton L, Pérez-Stable EJ. PMID: 28856013; PMCID: PMC5573262.
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    233. Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology. 2017 Mar 21; 88(12):1172-1179. Westwood AJ, Beiser A, Jain N, Himali JJ, DeCarli C, Auerbach SH, Pase MP, Seshadri S. PMID: 28228567; PMCID: PMC5373785.
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    234. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738. Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Alzheimer's Disease Genetics Consortium, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. PMID: 28183528; PMCID: PMC5496797.
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    235. Neighborhood Socioeconomic Status and Cognitive Trajectories in a Diverse Longitudinal Cohort. Clin Gerontol. 2018 Jan-Feb; 41(1):82-93. Meyer OL, Mungas D, King J, Hinton L, Farias S, Reed B, DeCarli C, Geraghty E, Beckett L. PMID: 28452649; PMCID: PMC5522784.
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    236. Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study. Stroke. 2017 03; 48(3):781-783. Romero JR, Preis SR, Beiser A, Himali JJ, Shoamanesh A, Wolf PA, Kase CS, Vasan RS, DeCarli C, Seshadri S. PMID: 28143923; PMCID: PMC5330856.
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    237. Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage: The Northern Manhattan Study. Stroke. 2017 03; 48(3):604-610. Katan M, Moon Y, von Eckardstein A, Spanaus K, DeRosa J, Gutierrez J, DeCarli C, Wright C, Sacco R, Elkind M. PMID: 28123058; PMCID: PMC5330783.
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    238. Independent value added by diffusion MRI for prediction of cognitive function in older adults. Neuroimage Clin. 2017; 14:166-173. Scott JA, Tosun D, Braskie MN, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT, ADNI. PMID: 28180075; PMCID: PMC5279696.
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    239. Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 01 18; 8:13624. Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CRK, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jørgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Muñoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LMO, Oosterlaan J, Papmeyer M, Pirpamer L, Pütz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Sämann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJM, De Geus EJC, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HHH, Green RC, Gruber O, Gudnason V, Guelfi S, Håberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Hulshoff Pol HE, Ikeda M, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hernández MCV, Van der Brug M, van der Lugt A, van der Wee NJA, Van Haren NEM, et al. PMID: 28098162; PMCID: PMC5253632.
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    240. Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease. Sci Rep. 2017 01 12; 7:39880. Huang M, Yang W, Feng Q, Chen W, Alzheimer’s Disease Neuroimaging Initiative. PMID: 28079104; PMCID: PMC5227696.
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    241. MRI Markers Predict Cognitive Decline Assessed by Telephone Interview: The Northern Manhattan Study. Alzheimer Dis Assoc Disord. 2017 Jan-Mar; 31(1):34-40. Wright CB, Dong C, Caunca MR, DeRosa J, Kuen Cheng Y, Rundek T, Elkind MS, DeCarli C, Sacco RL. PMID: 27467026; PMCID: PMC5272913.
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    242. Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study). Stroke. 2017 02; 48(2):486-489. Lioutas VA, Beiser A, Himali J, Aparicio H, Romero JR, DeCarli C, Seshadri S. PMID: 28008091; PMCID: PMC5288009.
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    243. Left ventricular mass-geometry and silent cerebrovascular disease: The Cardiovascular Abnormalities and Brain Lesions (CABL) study. Am Heart J. 2017 Mar; 185:85-92. Nakanishi K, Jin Z, Homma S, Elkind MS, Rundek T, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 28267479; PMCID: PMC5341701.
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    244. The Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement. 2017 Jun; 13(6):624-633. Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG. PMID: 27960092.
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    245. Relation of Dysglycemia to Structural Brain Changes in a Multiethnic Elderly Cohort. J Am Geriatr Soc. 2017 Feb; 65(2):277-285. Reitz C, Guzman VA, Narkhede A, DeCarli C, Brickman AM, Luchsinger JA. PMID: 27917464; PMCID: PMC5311018.
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    246. Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort. Neuroimage Clin. 2017; 13:130-137. Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil JP, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 27981028; PMCID: PMC5144753.
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    247. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016 Nov 29; 87(22):2324-2332. Zhan X, Stamova B, Jin LW, DeCarli C, Phinney B, Sharp FR. PMID: 27784770; PMCID: PMC5135029.
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    248. Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease. Stroke. 2016 11; 47(11):2813-2819. Tugcu A, Jin Z, Homma S, Elkind MS, Rundek T, Yoshita M, DeCarli C, Nakanishi K, Shames S, Wright CB, Sacco RL, Di Tullio MR. PMID: 27729581; PMCID: PMC5134895.
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    249. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582. Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, et al. PMID: 27694991; PMCID: PMC5227112.
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    250. Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis. JAMA Neurol. 2016 Oct 01; 73(10):1208-1216. Yassine HN, Feng Q, Azizkhanian I, Rawat V, Castor K, Fonteh AN, Harrington MG, Zheng L, Reed BR, DeCarli C, Jagust WJ, Chui HC. PMID: 27532692.
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    251. Progression from normal cognition to mild cognitive impairment in a diverse clinic-based and community-based elderly cohort. Alzheimers Dement. 2017 Apr; 13(4):399-405. Chen Y, Denny KG, Harvey D, Farias ST, Mungas D, DeCarli C, Beckett L. PMID: 27590706; PMCID: PMC5451154.
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    252. Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults. Neurobiol Aging. 2016 12; 48:48-52. Scott JA, Braskie MN, Tosun D, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT, ADNI. PMID: 27639120; PMCID: PMC5798609.
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    253. METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. Alzheimers Dement. 2016 12; 12(12):1235-1249. METACOHORTS Consortium. Electronic address: joanna.wardlaw@ed.ac.uk, METACOHORTS Consortium. PMID: 27490018; PMCID: PMC5399602.
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    254. Association of Physical Function with Clinical and Subclinical Brain Disease: The Framingham Offspring Study. J Alzheimers Dis. 2016 07 14; 53(4):1597-608. Camargo EC, Weinstein G, Beiser AS, Tan ZS, DeCarli C, Kelly-Hayes M, Kase C, Murabito JM, Seshadri S. PMID: 27540965.
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    255. Association between atrial fibrillation and volumetric magnetic resonance imaging brain measures: Framingham Offspring Study. Heart Rhythm. 2016 10; 13(10):2020-4. Piers RJ, Nishtala A, Preis SR, DeCarli C, Wolf PA, Benjamin EJ, Au R. PMID: 27417740; PMCID: PMC5035234.
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    256. Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis. Nat Commun. 2016 06 21; 7:11934. Iturria-Medina Y, Sotero RC, Toussaint PJ, Mateos-Pérez JM, Evans AC, Alzheimer’s Disease Neuroimaging Initiative. PMID: 27327500; PMCID: PMC4919512.
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    257. Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia. Stroke. 2016 05; 47(5):1201-6. Pase MP, Beiser A, Enserro D, Xanthakis V, Aparicio H, Satizabal CL, Himali JJ, Kase CS, Vasan RS, DeCarli C, Seshadri S. PMID: 27073239; PMCID: PMC5006676.
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    258. Effects of white matter integrity and brain volumes on late life depression in the Framingham Heart Study. Int J Geriatr Psychiatry. 2017 02; 32(2):214-221. Qiu WQ, Himali JJ, Wolf PA, DeCarli DC, Beiser A, Au R. PMID: 27059548; PMCID: PMC5052093.
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    259. Neck Circumference, Brain Imaging Measures, and Neuropsychological Testing Measures. J Stroke Cerebrovasc Dis. 2016 Jul; 25(7):1570-1581. Therkelsen KE, Preis SR, Beiser A, DeCarli C, Seshadri S, Wolf P, Au R, Fox CS. PMID: 27056441.
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    260. Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 18; 5(3):e002377. Romero JR, Preis SR, Beiser A, DeCarli C, D'Agostino RB, Wolf PA, Vasan RS, Polak JF, Seshadri S. PMID: 26994127; PMCID: PMC4943235.
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    261. Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study. Stroke. 2016 Apr; 47(4):1030-6. Maillard P, Mitchell GF, Himali JJ, Beiser A, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. PMID: 26965846; PMCID: PMC4811686.
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    262. Fibroblast Growth Factor 23 Is Associated With Subclinical Cerebrovascular Damage: The Northern Manhattan Study. Stroke. 2016 Apr; 47(4):923-8. Wright CB, Shah NH, Mendez AJ, DeRosa JT, Yoshita M, Elkind MS, Sacco RL, DeCarli C, Rundek T, Silverberg S, Dong C, Wolf M. PMID: 26956260; PMCID: PMC4811730.
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    263. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging. 2016 May; 41:200.e13-200.e20. Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK, Alzheimer's Disease Genetics Consortium (ADGC). PMID: 27036079; PMCID: PMC4948179.
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    264. 25-Hydroxyvitamin D in Patients With Cognitive Decline-Reply. JAMA Neurol. 2016 Mar; 73(3):358. Miller JW, Green R, DeCarli C. PMID: 26751272; PMCID: PMC5024784.
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    265. Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One. 2016; 11(2):e0148717. Karch CM, Ezerskiy LA, Bertelsen S, Alzheimer’s Disease Genetics Consortium (ADGC), Goate AM. PMID: 26919393; PMCID: PMC4769299.
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    266. β-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individuals. Neurobiol Aging. 2016 Apr; 40:173-180. Fletcher E, Villeneuve S, Maillard P, Harvey D, Reed B, Jagust W, DeCarli C. PMID: 26973117; PMCID: PMC4792128.
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    267. Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016 Apr 05; 86(14):1313-1319. Spartano NL, Himali JJ, Beiser AS, Lewis GD, DeCarli C, Vasan RS, Seshadri S. PMID: 26865519; PMCID: PMC4826343.
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    268. Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology. 2016 Feb 16; 86(7):619-26. Tsao CW, Himali JJ, Beiser AS, Larson MG, DeCarli C, Vasan RS, Mitchell GF, Seshadri S. PMID: 26791155; PMCID: PMC4762417.
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    269. Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension. 2016 Mar; 67(3):513-9. Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S. PMID: 26754644; PMCID: PMC4752398.
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    270. Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. J Alzheimers Dis. 2016; 51(2):451-61. Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, DeCarli C, Vasan RS, Wang TJ, Himali JJ, Annweiler C, Seshadri S. PMID: 26890771; PMCID: PMC4911705.
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    271. Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study. Stroke. 2016 Feb; 47(2):383-9. Nayor M, Enserro DM, Beiser AS, Cheng S, DeCarli C, Vasan RS, Seshadri S. PMID: 26696648; PMCID: PMC4729607.
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    272. Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. Front Aging Neurosci. 2015; 7:221. Scott JA, Braskie MN, Tosun D, Thompson PM, Weiner M, DeCarli C, Carmichael OT, Alzheimer’s Disease Neuroimaging Initiative. PMID: 26648866; PMCID: PMC4664630.
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    273. Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury. Alzheimers Dement. 2016 Apr; 12(4):438-45. Pase MP, Beiser A, Aparicio H, DeCarli C, Vasan RS, Murabito J, Seshadri S. PMID: 26542262; PMCID: PMC4841714.
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    274. Vitamin D Status and Rates of Cognitive Decline in a Multiethnic Cohort of Older Adults. JAMA Neurol. 2015 Nov; 72(11):1295-303. Miller JW, Harvey DJ, Beckett LA, Green R, Farias ST, Reed BR, Olichney JM, Mungas DM, DeCarli C. PMID: 26366714; PMCID: PMC5023277.
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    275. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23. Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith PA, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, St George-Hyslop P, Mayeux R, Rogaeva E, Alzheimer’s Disease Genetics Consortium. PMID: 26366463; PMCID: PMC4641052.
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    276. A priori collaboration in population imaging: The Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium. Alzheimers Dement (Amst). 2015 Dec; 1(4):513-20. Adams HH, Hilal S, Schwingenschuh P, Wittfeld K, van der Lee SJ, DeCarli C, Vernooij MW, Katschnig-Winter P, Habes M, Chen C, Seshadri S, van Duijn CM, Ikram MK, Grabe HJ, Schmidt R, Ikram MA. PMID: 27239529; PMCID: PMC4879491.
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    277. White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke. 2015 Nov; 46(11):3048-57. Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, Callisaya M, Chauhan G, de Craen AJ, Dufouil C, van Duijn CM, Ford I, Freudenberger P, Gottesman RF, Gudnason V, Heiss G, Hofman A, Lumley T, Martinez O, Mazoyer B, Moran C, Niessen WJ, Phan T, Psaty BM, Satizabal CL, Sattar N, Schilling S, Shibata DK, Slagboom PE, Smith A, Stott DJ, Taylor KD, Thomson R, Töglhofer AM, Tzourio C, van Buchem M, Wang J, Westendorp RG, Windham BG, Vernooij MW, Zijdenbos A, Beare R, Debette S, Ikram MA, Jukema JW, Launer LJ, Longstreth WT, Mosley TH, Seshadri S, Schmidt H, Schmidt R, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. PMID: 26451028; PMCID: PMC4749149.
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    278. Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities. Twin Res Hum Genet. 2015 Dec; 18(6):738-45. Luciano M, Marioni RE, Valdés Hernández M, Muñoz Maniega S, Hamilton IF, Royle NA, Generation Scotland, Chauhan G, Bis JC, Debette S, DeCarli C, Fornage M, Schmidt R, Ikram MA, Launer LJ, Seshadri S, Bastin ME, Porteous DJ, Wardlaw J, Deary IJ, CHARGE Consortium. PMID: 26427786; PMCID: PMC4747328.
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    279. Editorial Transition at Alzheimer's Disease and Associated Disorders. Alzheimer Dis Assoc Disord. 2015 Oct-Dec; 29(4):277-8. DeCarli C. PMID: 26492327.
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    280. Infectious Burden and Cognitive Decline in the Northern Manhattan Study. J Am Geriatr Soc. 2015 Aug; 63(8):1540-5. Wright CB, Gardener H, Dong C, Yoshita M, DeCarli C, Sacco RL, Stern Y, Elkind MS. PMID: 26289683; PMCID: PMC4878014.
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    281. Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke. Stroke. 2015 Sep; 46(9):2568-75. Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL, Vasan RS, Seshadri S. PMID: 26219649; PMCID: PMC4550531.
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    282. Large-scale genomics unveil polygenic architecture of human cortical surface area. Nat Commun. 2015 Jul 20; 6:7549. Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, Pediatric Imaging Neurocognition and Genetics Study, Alzheimer's Disease Neuroimaging Initiative. PMID: 26189703; PMCID: PMC4518289.
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    283. Cognitive correlates of white matter lesion load and brain atrophy: the Northern Manhattan Study. Neurology. 2015 Aug 04; 85(5):441-9. Dong C, Nabizadeh N, Caunca M, Cheung YK, Rundek T, Elkind MS, DeCarli C, Sacco RL, Stern Y, Wright CB. PMID: 26156514; PMCID: PMC4534076.
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    284. Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. Jack CR, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M. PMID: 26194310; PMCID: PMC4523217.
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    285. Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. Ann Neurol. 2015 Aug; 78(2):211-21. Kao PF, Chen YR, Liu XB, DeCarli C, Seeley WW, Jin LW. PMID: 25921485; PMCID: PMC4822421.
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    286. Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Med. 2015 Jun; 12(6):e1001841; discussion e1001841. Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Alzheimer’s Disease Genetics Consortium, GERAD1 Consortium, EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. PMID: 26079503; PMCID: PMC4469461.
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    287. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec; 11(12):1480-1488. Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. PMID: 26079413; PMCID: PMC4677060.
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    288. Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. Alzheimers Dement. 2015 Dec; 11(12):1439-1451. Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM, Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators, Alzheimer's Disease Genetics Consortium. PMID: 26079416; PMCID: PMC4676945.
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    289. Subclinical cerebrovascular disease inversely associates with learning ability: The NOMAS. Neurology. 2015 Jun 09; 84(23):2362-7. Glazer H, Dong C, Yoshita M, Rundek T, Elkind MS, Sacco RL, DeCarli C, Stern Y, Wright CB. PMID: 26002489; PMCID: PMC4464740.
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    290. Blood pressure control and cognitive performance: something to think about with aging. JAMA. 2015 May 19; 313(19):1963-4. DeCarli C. PMID: 25988465; PMCID: PMC5540364.
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    291. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nat Commun. 2015 May 19; 6:6760. Ayton S, Faux NG, Bush AI, Alzheimer's Disease Neuroimaging Initiative. PMID: 25988319; PMCID: PMC4479012.
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    292. Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015 Jul; 138(Pt 7):2020-33. Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin LW, Huang EJ, Grinberg LT, DeCarli C, Seeley WW, Jagust W. PMID: 25953778; PMCID: PMC4806716.
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    293. Glucose indices are associated with cognitive and structural brain measures in young adults. Neurology. 2015 Jun 09; 84(23):2329-37. Weinstein G, Maillard P, Himali JJ, Beiser AS, Au R, Wolf PA, Seshadri S, DeCarli C. PMID: 25948725; PMCID: PMC4464744.
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    294. A call for new thoughts about what might influence human brain aging: aging, apolipoprotein E, and amyloid. JAMA Neurol. 2015 May; 72(5):500-2. DeCarli C. PMID: 25775040; PMCID: PMC4428918.
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    295. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke. 2015 May; 46(5):1161-6. Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. PMID: 25908455; PMCID: PMC4414870.
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    296. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. JAMA Neurol. 2015 Apr; 72(4):414-22. Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, Haase CM, Miller J, Poon WW, Rosen A, Rosen H, Sapozhnikova A, Shapira J, Varpetian A, Foroud TM, Levenson RW, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Coppola G. PMID: 25706306; PMCID: PMC4397175.
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    297. Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia. Am J Geriatr Psychiatry. 2016 Feb; 24(2):126-35. Sacuiu S, Insel PS, Mueller S, Tosun D, Mattsson N, Jack CR, DeCarli C, Petersen R, Aisen PS, Weiner MW, Mackin RS, Alzheimer's Disease Neuroimaging Initiative. PMID: 26238228; PMCID: PMC4973623.
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    298. White matter hyperintensities among older adults are associated with futile increase in frontal activation and functional connectivity during spatial search. PLoS One. 2015; 10(3):e0122445. Lockhart SN, Luck SJ, Geng J, Beckett L, Disbrow EA, Carmichael O, DeCarli C. PMID: 25793922; PMCID: PMC4368687.
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    299. Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study. Am J Alzheimers Dis Other Demen. 2015 Sep; 30(6):622-8. Libon DJ, Preis SR, Beiser AS, Devine S, Seshadri S, Wolf PA, DeCarli C, Au R. PMID: 25788434; PMCID: PMC4536169.
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    300. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17. Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L, IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. PMID: 25778476; PMCID: PMC4573764.
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    301. Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. PLoS One. 2015; 10(3):e0118338. Yokoyama JS, Lee AK, Takada LT, Busovaca E, Bonham LW, Chao SZ, Tse M, He J, Schwarz CG, Carmichael OT, Matthews BR, Karydas A, Weiner MW, Coppola G, DeCarli CS, Miller BL, Rosen HJ. PMID: 25738563; PMCID: PMC4349764.
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    302. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet. 2015 Apr; 8(2):398-409. Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M. PMID: 25663218; PMCID: PMC4427240.
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    303. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25531812; PMCID: PMC4324097.
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    304. Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study. Neurology. 2015 Feb 24; 84(8):825-32. Shoamanesh A, Preis SR, Beiser AS, Vasan RS, Benjamin EJ, Kase CS, Wolf PA, DeCarli C, Romero JR, Seshadri S. PMID: 25632086; PMCID: PMC4345647.
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    305. Cooccurrence of vascular risk factors and late-life white-matter integrity changes. Neurobiol Aging. 2015 Apr; 36(4):1670-1677. Maillard P, Carmichael OT, Reed B, Mungas D, DeCarli C. PMID: 25666995; PMCID: PMC4380772.
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    306. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. PMID: 25670335; PMCID: PMC4391343.
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    307. Structural MRI Predictors of Late-Life Cognition Differ Across African Americans, Hispanics, and Whites. Curr Alzheimer Res. 2015; 12(7):632-9. Zahodne LB, Manly JJ, Narkhede A, Griffith EY, DeCarli C, Schupf NS, Mayeux R, Brickman AM. PMID: 26027808; PMCID: PMC4872300.
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    308. Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(4):1213-29. Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp FR. PMID: 25697841; PMCID: PMC4422390.
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    309. The role of carotid intima-media thickness in predicting longitudinal cognitive function in an older adult cohort. Cerebrovasc Dis. 2014; 38(6):441-7. Frazier DT, Seider T, Bettcher BM, Mack WJ, Jastrzab L, Chao L, Weiner MW, DeCarli C, Reed BR, Mungas D, Chui HC, Kramer JH. PMID: 25502351; PMCID: PMC4303029.
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    310. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Alzheimer Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25199842; PMCID: PMC4314944.
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    311. Donepezil treatment in ethnically diverse patients with Alzheimer disease. Am J Geriatr Psychiatry. 2015 Apr; 23(4):384-390. Tinklenberg JR, Kraemer HC, Yaffe K, O'Hara R, Ringman JM, Ashford JW, Yesavage JA, Taylor JL, California Alzheimer's Disease Centers. PMID: 25747405; PMCID: PMC4874327.
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    312. The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity. Alzheimers Dement. 2015 Feb; 11(2):111-25. Frisoni GB, Jack CR, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, deToledo-Morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O'Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deLeon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M, EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzh. PMID: 25267715; PMCID: PMC4422168.
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    314. Structural imaging measures of brain aging. Neuropsychol Rev. 2014 Sep; 24(3):271-89. Lockhart SN, DeCarli C. PMID: 25146995; PMCID: PMC4163469.
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    315. Neuroimaging of the aging brain: introduction to the special issue of neuropsychology review. Neuropsychol Rev. 2014 Sep; 24(3):267-70. Lockhart S, DeCarli C, Fama R. PMID: 25146996; PMCID: PMC4262518.
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    316. Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance. Alzheimers Dement. 2015 Feb; 11(2):126-38. Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack CR, Frisoni GB, EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. PMID: 25130658; PMCID: PMC4419736.
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    317. ERP abnormalities elicited by word repetition in fragile X-associated tremor/ataxia syndrome (FXTAS) and amnestic MCI. Neuropsychologia. 2014 Oct; 63:34-42. Yang JC, Chi L, Teichholtz S, Schneider A, Nanakul R, Nowacki R, Seritan A, Reed B, DeCarli C, Iragui VJ, Kutas M, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 25111034; PMCID: PMC4194142.
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    318. Lipid profile components and subclinical cerebrovascular disease in the northern Manhattan study. Cerebrovasc Dis. 2014; 37(6):423-30. Willey JZ, Gardener H, Moon YP, Yoshita M, DeCarli C, Cheung YK, Sacco RL, Elkind MS, Wright CB. PMID: 25034465; PMCID: PMC4142052.
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    319. Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):226-33. Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp FR. PMID: 24731980; PMCID: PMC4139468.
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    320. Association between neuropathology and brain volume in the Framingham Heart Study. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):219-25. Kaur B, Himali JJ, Seshadri S, Beiser AS, Au R, McKee AC, Auerbach S, Wolf PA, DeCarli CS. PMID: 24614264; PMCID: PMC4139422.
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    321. Vascular risk and Aβ interact to reduce cortical thickness in AD vulnerable brain regions. Neurology. 2014 Jul 01; 83(1):40-7. Villeneuve S, Reed BR, Madison CM, Wirth M, Marchant NL, Kriger S, Mack WJ, Sanossian N, DeCarli C, Chui HC, Weiner MW, Jagust WJ. PMID: 24907234; PMCID: PMC4114172.
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    322. Early Brain Loss in Circuits Affected by Alzheimer's Disease is Predicted by Fornix Microstructure but may be Independent of Gray Matter. Front Aging Neurosci. 2014; 6:106. Fletcher E, Carmichael O, Pasternak O, Maier-Hein KH, DeCarli C. PMID: 24904414; PMCID: PMC4035735.
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    325. White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain. Stroke. 2014 Jun; 45(6):1721-6. Maillard P, Fletcher E, Lockhart SN, Roach AE, Reed B, Mungas D, DeCarli C, Carmichael OT. PMID: 24781079; PMCID: PMC4102626.
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    326. Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke. 2014 May; 45(5):1492-4. Romero JR, Preis SR, Beiser A, DeCarli C, Viswanathan A, Martinez-Ramirez S, Kase CS, Wolf PA, Seshadri S. PMID: 24713533; PMCID: PMC4048617.
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    327. Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014 May 06; 82(18):1613-9. Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. PMID: 24706014; PMCID: PMC4013812.
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    328. Myelin injury and degraded myelin vesicles in Alzheimer's disease. Curr Alzheimer Res. 2014 Mar; 11(3):232-8. Zhan X, Jickling GC, Ander BP, Liu D, Stamova B, Cox C, Jin LW, DeCarli C, Sharp FR. PMID: 24484278; PMCID: PMC4066812.
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    329. Associations between serum cholesterol levels and cerebral amyloidosis. JAMA Neurol. 2014 Feb; 71(2):195-200. Reed B, Villeneuve S, Mack W, DeCarli C, Chui HC, Jagust W. PMID: 24378418; PMCID: PMC4083819.
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    330. Cortical thickness mediates the effect of β-amyloid on episodic memory. Neurology. 2014 Mar 04; 82(9):761-7. Villeneuve S, Reed BR, Wirth M, Haase CM, Madison CM, Ayakta N, Mack W, Mungas D, Chui HC, DeCarli C, Weiner MW, Jagust WJ. PMID: 24489134; PMCID: PMC3945649.
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    331. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Mar; 127(3):407-18. Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, DeCarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White CL, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin AS. PMID: 24442578; PMCID: PMC4003885.
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    332. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014 Feb; 45(2):403-12. Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, Schmidt H, Lahti J, Heckbert SR, Lumley T, Rice K, Rotter JI, Taylor KD, Folsom AR, Boerwinkle E, Rosamond WD, Shahar E, Gottesman RF, Koudstaal PJ, Amin N, Wieberdink RG, Dehghan A, Hofman A, Uitterlinden AG, Destefano AL, Debette S, Xue L, Beiser A, Wolf PA, Decarli C, Ikram MA, Seshadri S, Mosley TH, Longstreth WT, van Duijn CM, Launer LJ. PMID: 24436238; PMCID: PMC3955258.
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    333. Biological heterogeneity in ADNI amnestic mild cognitive impairment. Alzheimers Dement. 2014 Sep; 10(5):511-521.e1. Nettiksimmons J, DeCarli C, Landau S, Beckett L, Alzheimer's Disease Neuroimaging Initiative. PMID: 24418061; PMCID: PMC4092059.
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    334. Longitudinal trajectories of everyday function by diagnostic status. Psychol Aging. 2013 Dec; 28(4):1070-5. Farias ST, Chou E, Harvey DJ, Mungas D, Reed B, DeCarli C, Park LQ, Beckett L. PMID: 24364409; PMCID: PMC4021720.
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    335. Parental longevity is associated with cognition and brain ageing in middle-aged offspring. Age Ageing. 2014 May; 43(3):358-63. Murabito JM, Beiser AS, Decarli C, Seshadri S, Wolf PA, Au R. PMID: 24212919; PMCID: PMC4001170.
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    336. Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals. JAMA Neurol. 2013 Nov; 70(11):1389-95. Fletcher E, Raman M, Huebner P, Liu A, Mungas D, Carmichael O, DeCarli C. PMID: 24018960; PMCID: PMC4059679.
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    337. White matter hyperintensities are associated with visual search behavior independent of generalized slowing in aging. Neuropsychologia. 2014 Jan; 52:93-101. Lockhart SN, Roach AE, Luck SJ, Geng J, Beckett L, Carmichael O, DeCarli C. PMID: 24183716; PMCID: PMC3924853.
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    338. Amylin: what might be its role in Alzheimer's disease and how could this affect therapy? Expert Rev Proteomics. 2013 Oct; 10(5):403-5. Despa F, Decarli C. PMID: 24117198; PMCID: PMC4068803.
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    339. Alcohol intake and brain structure in a multiethnic elderly cohort. Clin Nutr. 2014 Aug; 33(4):662-7. Gu Y, Scarmeas N, Short EE, Luchsinger JA, DeCarli C, Stern Y, Manly JJ, Schupf N, Mayeux R, Brickman AM. PMID: 24011900; PMCID: PMC4048329.
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    340. Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology. 2013 Sep 10; 81(11):984-91. Tsao CW, Seshadri S, Beiser AS, Westwood AJ, Decarli C, Au R, Himali JJ, Hamburg NM, Vita JA, Levy D, Larson MG, Benjamin EJ, Wolf PA, Vasan RS, Mitchell GF. PMID: 23935179; PMCID: PMC3888200.
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    345. Subclinical left ventricular dysfunction and silent cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Circulation. 2013 Sep 03; 128(10):1105-11. Russo C, Jin Z, Homma S, Elkind MS, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 23902759; PMCID: PMC4370621.
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    348. APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology. 2013 Jul 16; 81(3):292-300. Schilling S, DeStefano AL, Sachdev PS, Choi SH, Mather KA, DeCarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. PMID: 23858411; PMCID: PMC3770168.
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    349. Amylin deposition in the brain: A second amyloid in Alzheimer disease? Ann Neurol. 2013 Oct; 74(4):517-26. Jackson K, Barisone GA, Diaz E, Jin LW, DeCarli C, Despa F. PMID: 23794448; PMCID: PMC3818462.
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    350. Extrapyramidal signs by dementia severity in Alzheimer disease and dementia with Lewy bodies. Alzheimer Dis Assoc Disord. 2013 Jul-Sep; 27(3):226-32. Kaur B, Harvey DJ, Decarli CS, Zhang L, Sabbagh MN, Olichney JM. PMID: 23023095; PMCID: PMC3562426.
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    355. Ventricular enlargement and its clinical correlates in the imaging cohort from the ADCS MCI donepezil/vitamin E study. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):174-81. Apostolova LG, Babakchanian S, Hwang KS, Green AE, Zlatev D, Chou YY, DeCarli C, Jack CR, Petersen RC, Aisen PS, Cummings JL, Toga AW, Thompson PM. PMID: 23694947; PMCID: PMC3662002.
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    356. Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls. Neurobiol Aging. 2013 Aug; 34(8):1996-2002. Barnes J, Carmichael OT, Leung KK, Schwarz C, Ridgway GR, Bartlett JW, Malone IB, Schott JM, Rossor MN, Biessels GJ, DeCarli C, Fox NC, Alzheimer's Disease Neuroimaging Initiative. PMID: 23522844; PMCID: PMC3810644.
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    357. Effects of T2-Weighted MRI Based Cranial Volume Measurements on Studies of the Aging Brain. Proc SPIE Int Soc Opt Eng. 2013 Mar 13; 8669. Vuong P, Drucker D, Schwarz C, Fletcher E, Decarli C, Carmichael O. PMID: 24353391; PMCID: PMC3864960.
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    366. Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease. Brain Imaging Behav. 2012 Dec; 6(4):551-67. Nho K, Risacher SL, Crane PK, DeCarli C, Glymour MM, Habeck C, Kim S, Lee GJ, Mormino E, Mukherjee S, Shen L, West JD, Saykin AJ, Alzheimer’s Disease Neuroimaging Initiative--ADNI. PMID: 23070747; PMCID: PMC3532574.
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    367. Relationship between baseline brain metabolism measured using [¹⁸F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease. Brain Imaging Behav. 2012 Dec; 6(4):568-83. Habeck C, Risacher S, Lee GJ, Glymour MM, Mormino E, Mukherjee S, Kim S, Nho K, DeCarli C, Saykin AJ, Crane PK, Alzheimer’s Disease Neuroimaging Initiative. PMID: 23179062; PMCID: PMC3532575.
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    368. Genetic architecture of resilience of executive functioning. Brain Imaging Behav. 2012 Dec; 6(4):621-33. Mukherjee S, Kim S, Gibbons LE, Nho K, Risacher SL, Glymour MM, Habeck C, Lee GJ, Mormino E, Ertekin-Taner N, Montine TJ, Decarli C, Saykin AJ, Crane PK, Alzheimer’s Disease Neuroimaging Initiative. PMID: 22711244; PMCID: PMC3607298.
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    369. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54. Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alzheimer's Disease Genetics Consortium, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. PMID: 23143602; PMCID: PMC3510344.
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    370. Next frontiers in the genetic epidemiology of Alzheimer's disease. Eur J Epidemiol. 2012 Nov; 27(11):831-6. Ikram MA, DeCarli C. PMID: 23132737; PMCID: PMC3774602.
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    371. Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study. Lancet Neurol. 2012 Dec; 11(12):1039-47. Maillard P, Seshadri S, Beiser A, Himali JJ, Au R, Fletcher E, Carmichael O, Wolf PA, DeCarli C. PMID: 23122892; PMCID: PMC3510663.
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    372. Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimers Dement. 2013 May; 9(3):332-7. Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, DeCarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR, Alzheimer’s Disease Neuroimaging Initiative. PMID: 23110865; PMCID: PMC3891834.
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    373. Combining boundary-based methods with tensor-based morphometry in the measurement of longitudinal brain change. IEEE Trans Med Imaging. 2013 Feb; 32(2):223-36. Fletcher E, Knaack A, Singh B, Lloyd E, Wu E, Carmichael O, DeCarli C, Alzheimer’s Disease Neuroimaging Initiative. PMID: 23014714; PMCID: PMC3775845.
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    374. Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults. Stroke. 2012 Nov; 43(11):2865-70. Cardenas VA, Reed B, Chao LL, Chui H, Sanossian N, DeCarli CC, Mack W, Kramer J, Hodis HN, Yan M, Buonocore MH, Carmichael O, Jagust WJ, Weiner MW. PMID: 22984010; PMCID: PMC3732460.
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    375. Lipoprotein phospholipase A2 and cerebral microbleeds in the Framingham Heart Study. Stroke. 2012 Nov; 43(11):3091-4. Romero JR, Preis SR, Beiser AS, DeCarli C, Lee DY, Viswanathan A, Benjamin EJ, Fontes J, Au R, Pikula A, Wang J, Kase CS, Wolf PA, Irrizary MC, Seshadri S. PMID: 22961963; PMCID: PMC3544291.
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    376. Different associations of white matter lesions with depression and cognition. BMC Neurol. 2012 Aug 25; 12:83. Lee JY, Insel P, Mackin RS, Schuff N, Chui H, DeCarli C, Park KH, Mueller SG, Weiner MW. PMID: 22920586; PMCID: PMC3482604.
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    377. Coevolution of white matter hyperintensities and cognition in the elderly. Neurology. 2012 Jul 31; 79(5):442-8. Maillard P, Carmichael O, Fletcher E, Reed B, Mungas D, DeCarli C. PMID: 22815562; PMCID: PMC3405254.
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    378. Multiple loci influencing hippocampal degeneration identified by genome scan. Ann Neurol. 2012 Jul; 72(1):65-75. Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA, Alzheimer's Disease Neuroimaging Initiative. PMID: 22745009; PMCID: PMC3405172.
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    379. Cerebrovascular disease: Assessing the brain as an end-organ of vascular disease. Nat Rev Cardiol. 2012 Jun 26; 9(8):435-6. DeCarli C. PMID: 22733217; PMCID: PMC4083477.
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    380. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N, Alzheimer's Disease Genetics Consortium (ADGC), Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL. PMID: 22722634; PMCID: PMC3398432.
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    381. FLAIR and diffusion MRI signals are independent predictors of white matter hyperintensities. AJNR Am J Neuroradiol. 2013 Jan; 34(1):54-61. Maillard P, Carmichael O, Harvey D, Fletcher E, Reed B, Mungas D, DeCarli C. PMID: 22700749; PMCID: PMC3710440.
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    382. Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetics. 2012 Jun 1; 44(6):732-732. Ikram IM, Fornage FM, Smith SA, Seshadri SS, Schmidt SR, Debette DS, Vrooman VH, Sigurdsson SS, Ropele RS, Taal TH, Mook-Kanamori MD, Coker CL, Longstreth LW, Niessen NW, DeStefano DA, Beiser BA, Zijdenbos ZA, Struchalin SM, Jack JC, Rivadeneira RF, Uitterlinden UA, Knopman KD, Hartikainen HA, Pennell PC, Thiering TE, Steegers SE, Hakonarson HH, Heinrich HJ, Palmer PL, Jarvelin JM, McCarthy MM, Grant GS, St Pourcain SB, Timpson TN, Smith SG, Sovio SU, Nalls NM, Au AR, Hofman HA, Gudnason GH, van der Lugt vA, Harris HT, Meeks MW, Vernooij VM, van Buchem vM, Catellier CD, Jaddoe JV, Gudnason GV, Windham WB, Wolf WP, van Duijn vC, Mosley MT, Schmidt SH, Launer LL, Breteler BM, DeCarli DC. .
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    383. Session II: Mechanisms of age-related cognitive change and targets for intervention: neural circuits, networks, and plasticity. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(7):747-53. DeCarli C, Kawas C, Morrison JH, Reuter-Lorenz PA, Sperling RA, Wright CB. PMID: 22570135; PMCID: PMC3732094.
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    384. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Alzheimer's Disease Genetics Consortium, Ross OA, Rademakers R, Schellenberg GD, Miller BL, Mandelkow E, Geschwind DH. PMID: 22556362; PMCID: PMC3392107.
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    385. The contributions of MRI-based measures of gray matter, white matter hyperintensity, and white matter integrity to late-life cognition. AJNR Am J Neuroradiol. 2012 Oct; 33(9):1797-803. He J, Wong VS, Fletcher E, Maillard P, Lee DY, Iosif AM, Singh B, Martinez O, Roach AE, Lockhart SN, Beckett L, Mungas D, Farias ST, Carmichael O, DeCarli C. PMID: 22538073; PMCID: PMC3694809.
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    386. Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 2012 Apr 15; 44(5):552-61. Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW, Alzheimer's Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study Group, Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM, Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium. PMID: 22504417; PMCID: PMC3635491.
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    387. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 Apr 15; 44(5):539-44. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U, Early Growth Genetics Consortium, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH, Schmidt H, Launer LJ, Breteler MM, DeCarli C, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. PMID: 22504418; PMCID: PMC3618290.
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    388. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet. 2012 Apr 15; 44(5):532-538. Taal HR, Pourcain BS, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BLK, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller M, O'Reilly PF, Prokopenko I, Rivadeneira F, Steegers EAP, Sunyer J, Tiesler C, Yaghootkar H, Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium, Breteler MMB, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH, Seshadri S, Smith AV, Vernooij MW, Early Genetics & Lifecourse Epidemiology (EAGLE) consortium, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Benet J, Grant SFA, Hartikainen AL, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann HE, Vissing NH, DeCarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin MR, Early Growth Genetics (EGG) Consortium, Jaddoe VWV. PMID: 22504419; PMCID: PMC3773913.
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    389. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. PMID: 22504421; PMCID: PMC3427729.
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    390. Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer's Disease. Front Aging Neurosci. 2012; 4:1. Lee DY, Fletcher E, Carmichael OT, Singh B, Mungas D, Reed B, Martinez O, Buonocore MH, Persianinova M, Decarli C. PMID: 22514534; PMCID: PMC3323836.
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    392. Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging. Front Hum Neurosci. 2012; 6:56. Lockhart SN, Mayda AB, Roach AE, Fletcher E, Carmichael O, Maillard P, Schwarz CG, Yonelinas AP, Ranganath C, Decarli C. PMID: 22438841; PMCID: PMC3305887.
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    393. Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging. Neurology. 2012 Feb 28; 78(9):658-64. Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, Decarli C, Wolf PA, Vasan RS, Robins SJ, Seshadri S. PMID: 22371413; PMCID: PMC3286229.
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    394. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiative, Pediatric Imaging, Neurocognition, and Genetics Study, Weiner M, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, et al. PMID: 22343285; PMCID: PMC3309762.
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    395. Mediterranean diet and white matter hyperintensity volume in the Northern Manhattan Study. Arch Neurol. 2012 Feb; 69(2):251-6. Gardener H, Scarmeas N, Gu Y, Boden-Albala B, Elkind MS, Sacco RL, DeCarli C, Wright CB. PMID: 22332193; PMCID: PMC3281550.
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