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Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases. Acta Neuropathol Commun. 2024 Aug 17; 12(1):134.
Scalco R, Oliveira LC, Lai Z, Harvey DJ, Abujamil L, DeCarli C, Jin LW, Chuah CN, Dugger BN. PMID: 39154006; PMCID: PMC11330038.
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Translation:
Humans
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Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age. Alzheimers Dement. 2024 Aug 12.
Charisis S, Short MI, Bernal R, Kautz TF, Treviño HA, Mathews J, Dediós AGV, Muhammad JAS, Luckey AM, Aslam A, Himali JJ, Shipp EL, Habes M, Beiser AS, DeCarli C, Scarmeas N, Ramachandran VS, Seshadri S, Maillard P, Satizabal CL. PMID: 39132759.
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Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function. Aging Dis. 2024 Aug 01; 15(4):1885-1898.
Liu X, Barisano G, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Maillard P, Satizabal CL, Fadaee E, Habes M, Stables L, Singh H, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM, Wang DJJ, MarkVCID Consortium. PMID: 37307817; PMCID: PMC11272201.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Associations of cerebral amyloid beta and tau with cognition from midlife. Alzheimers Dement. 2024 Jul 22.
Gonzales MM, O'Donnell A, Ghosh S, Thibault E, Tanner J, Satizabal CL, Decarli CS, Fakhri GE, Johnson KA, Beiser AS, Seshadri S, Pase M. PMID: 39039896.
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PubMed Mentions: Fields:
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Neurocognitive profiles are associated with subsequent brain integrity in a sample of Hispanics/Latinos: Findings from the SOL-INCA-MRI study (HCHS/SOL). Alzheimers Dement (Amst). 2024 Jul-Sep; 16(3):e12622.
Sapkota S, Maillard P, Stickel AM, Tarraf W, Gonzalez KA, Ivanovic V, Morlett-Paredes A, Cai J, Isasi CR, Lipton RB, Daviglus M, Testai FD, Lamar M, Gallo LC, Talavera GA, Agudelo C, Ramos AR, González HM, DeCarli C. PMID: 39021586; PMCID: PMC11253828.
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Associations of Amyloid Burden, White Matter Hyperintensities, and Hippocampal Volume With Cognitive Trajectories in the 90+ Study. Neurology. 2024 Aug 13; 103(3):e209665.
Wang J, Ackley S, Woodworth DC, Sajjadi SA, Decarli CS, Fletcher EF, Glymour MM, Jiang L, Kawas C, Corrada MM. PMID: 39008782; PMCID: PMC11249511.
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Translation:
Humans
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Kinetic modeling of 18 F-PI-2620 binding in the brain using an image-derived input function with total-body PET. bioRxiv. 2024 Jul 04.
Bhattarai A, Holy EN, Wang Y, Spencer BA, Wang G, DeCarli C, Fan AP. PMID: 39005369; PMCID: PMC11245027.
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Intracranial Volume Is Driven by Both Genetics and Early Life Exposures: The SOL-INCA-MRI Study. Ethn Dis. 2024 Feb; 34(2):103-112.
Sofer T, Granot-Hershkovitz E, Tarraf W, Filigrana P, Isasi CR, Suglia SF, Kaplan R, Taylor K, Daviglus ML, Testai FD, Zeng D, Cai J, Fornage M, González HM, DeCarli C. PMID: 38973806; PMCID: PMC11223032.
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PubMed Mentions: Fields:
Translation:
Humans
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Glycemic Control, Cognitive Aging, and Impairment Among Diverse Hispanic/Latino Individuals: Study of Latinos- Investigation of Neurocognitive Aging (Hispanic Community Health Study/Study of Latinos). Diabetes Care. 2024 Jul 01; 47(7):1152-1161.
González HM, Tarraf W, Stickel AM, Morlett A, González KA, Ramos AR, Rundek T, Gallo LC, Talavera GA, Daviglus ML, Lipton RB, Isasi C, Lamar M, Zeng D, DeCarli C. PMID: 38684486; PMCID: PMC11208749.
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Translation:
Humans
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Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos. Alzheimers Dement. 2024 Jul 01.
Xia R, Jian X, Rodrigue AL, Bressler J, Boerwinkle E, Cui B, Daviglus ML, DeCarli C, Gallo LC, Glahn DC, Knowles EEM, Moon JY, Mosley TH, Satizabal CL, Sofer T, Tarraf W, Testai F, Blangero J, Seshadri S, González HM, Fornage M. PMID: 38946675.
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PubMed Mentions: Fields:
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Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set. Neurobiol Aging. 2024 Oct; 142:1-7.
Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, deCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH. PMID: 39024720.
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The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathol Commun. 2024 05 24; 12(1):81.
Wang HP, Scalco R, Saito N, Beckett L, Nguyen ML, Huie EZ, Honig LS, DeCarli C, Rissman RA, Teich AF, Mungas DM, Jin LW, Dugger BN. PMID: 38790074; PMCID: PMC11127432.
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Translation:
HumansCells
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Cardiovascular disease risk exacerbates brain aging among Hispanic/Latino adults in the SOL-INCA-MRI Study. Front Aging Neurosci. 2024; 16:1390200.
Stickel AM, Tarraf W, Gonzalez KA, Paredes AM, Zeng D, Cai J, Isasi CR, Kaplan R, Lipton RB, Daviglus ML, Testai FD, Lamar M, Gallo LC, Talavera GA, Gellman MD, Ramos AR, Ivanovic V, Seiler S, González HM, DeCarli C. PMID: 38778863; PMCID: PMC11110680.
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Genetic variants for head size share genes and pathways with cancer. Cell Rep Med. 2024 May 21; 5(5):101529.
Knol MJ, Poot RA, Evans TE, Satizabal CL, Mishra A, Sargurupremraj M, van der Auwera S, Duperron MG, Jian X, Hostettler IC, van Dam-Nolen DHK, Lamballais S, Pawlak MA, Lewis CE, Carrion-Castillo A, van Erp TGM, Reinbold CS, Shin J, Scholz M, Håberg AK, Kämpe A, Li GHY, Avinun R, Atkins JR, Hsu FC, Amod AR, Lam M, Tsuchida A, Teunissen MWA, Aygün N, Patel Y, Liang D, Beiser AS, Beyer F, Bis JC, Bos D, Bryan RN, Bülow R, Caspers S, Catheline G, Cecil CAM, Dalvie S, Dartigues JF, DeCarli C, Enlund-Cerullo M, Ford JM, Franke B, Freedman BI, Friedrich N, Green MJ, Haworth S, Helmer C, Hoffmann P, Homuth G, Ikram MK, Jack CR, Jahanshad N, Jockwitz C, Kamatani Y, Knodt AR, Li S, Lim K, Longstreth WT, Macciardi F, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium, Mäkitie O, Mazoyer B, Medland SE, Miyamoto S, Moebus S, Mosley TH, Muetzel R, Mühleisen TW, Nagata M, Nakahara S, Palmer ND, Pausova Z, Preda A, Quidé Y, Reay WR, Roshchupkin GV, Schmidt R, Schreiner PJ, Setoh K, Shapland CY, Sidney S, St Pourcain B, Stein JL, Tabara Y, Teumer A, Uhlmann A, van der Lugt A, Vernooij MW, Werring DJ, Windham BG, Witte AV, Wittfeld K, Yang Q, Yoshida K, Brunner HG, Le Grand Q, Sim K, Stein DJ, Bowden DW, Cairns MJ, Hariri AR, Cheung CL, Andersson S, Villringer A, Paus T, Cichon S, Calhoun VD, Crivello F, Launer LJ, White T, Koudstaal PJ, Houlden H, Fornage M, Matsuda F, Grabe HJ, Ikram MA, Debette S, Thompson PM, Seshadri S, Adams HHH. PMID: 38703765; PMCID: PMC11148644.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Association of Incident Stroke Risk With an IL-18-Centered Inflammatory Network Biomarker Composite. Stroke. 2024 Jun; 55(6):1601-1608.
Martirosian RA, Wiedner CD, Sanchez J, Mun KT, Marla K, Teran C, Thirion M, Liebeskind DS, McGrath ER, Zucker JM, Bernal R, Beiser AS, DeCarli C, Himali JJ, Seshadri S, Hinman JD. PMID: 38690658.
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Humans
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Trends in Intracranial and Cerebral Volumes of Framingham Heart Study Participants Born 1930 to 1970. JAMA Neurol. 2024 May 01; 81(5):471-480.
DeCarli C, Maillard P, Pase MP, Beiser AS, Kojis D, Satizabal CL, Himali JJ, Aparicio HJ, Fletcher E, Seshadri S. PMID: 38526486; PMCID: PMC10964161.
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Humans
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Non-invasive quantification of 18F-florbetaben with total-body EXPLORER PET. EJNMMI Res. 2024 Apr 16; 14(1):39.
Holy EN, Li E, Bhattarai A, Fletcher E, Alfaro ER, Harvey DJ, Spencer BA, Cherry SR, DeCarli CS, Fan AP. PMID: 38625413; PMCID: PMC11021392.
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Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients. medRxiv. 2024 Apr 11.
Petersen M, Coenen M, DeCarli C, De Luca A, van der Lelij E, Alzheimer’s Disease Neuroimaging Initiative, Barkhof F, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Fletcher EF, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, Maillard PM, McCreary CR, Papma JM, Pijnenburg YAL, Schmidt R, Smith EE, Steketee RME, van den Berg E, van der Flier WM, Venkatraghavan V, Venketasubramanian N, Vernooij MW, Wolters FJ, Xu X, Horn A, Patil KR, Eickhoff SB, Thomalla G, Biesbroek JM, Biessels GJ, Cheng B. PMID: 38586023; PMCID: PMC10996741.
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Impaired Kidney Function, Cerebral Small Vessel Disease and Cognitive Disorders: The Framingham Heart Study. Nephrol Dial Transplant. 2024 Apr 02.
Kelly DM, Pinheiro AA, Koini M, Anderson CD, Aparicio H, Hofer E, Kern D, Blacker D, DeCarli C, Hwang SJ, Viswanathan A, Gonzales MM, Beiser AS, Seshadri S, Schmidt R, Demissie S, Romero JR. PMID: 38565317.
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Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients. Alzheimers Dement. 2024 04; 20(4):2980-2989.
Biesbroek JM, Coenen M, DeCarli C, Fletcher EM, Maillard PM, Alzheimer's Disease Neuroimaging Initiative, Barkhof F, Barnes J, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, Teunissen CE, van den Berg E, van der Flier WM, Venketasubramanian N, Venkatraghavan V, Vernooij MW, Wolters FJ, Xin X, Kuijf HJ, Biessels GJ. PMID: 38477469; PMCID: PMC11032573.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Associations between personality and psychological characteristics and cognitive outcomes among older adults. Psychol Aging. 2024 Mar; 39(2):188-198.
Tomaszewski Farias S, De Leon FS, Gavett BE, Fletcher E, Meyer OL, Whitmer RA, Whitmer RA, DeCarli C, Mungas D. PMID: 38330372; PMCID: PMC10911449.
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Humans
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Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024 Feb 27; 102(4):e208075.
Pase MP, Himali JJ, Puerta R, Beiser AS, Gonzales MM, Satizabal CL, Yang Q, Aparicio HJ, Kojis DJ, Decarli CS, Lopez OL, Longstreth W, Gudnason V, Mosley TH, Bis JC, Fohner A, Psaty BM, Boada M, García-González P, Valero S, Marquié M, Tracy R, Launer LJ, Ruiz A, Fornage M, Seshadri S. PMID: 38290090.
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Humans
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Individuals with Alzheimer's disease and low tau burden: Characteristics and implications. Alzheimers Dement. 2024 03; 20(3):2113-2127.
Landau SM, Lee J, Murphy A, Ward TJ, Harrison TM, Baker SL, DeCarli C, Harvey D, Tosun D, Weiner MW, Koeppe RA, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative. PMID: 38241084; PMCID: PMC10984443.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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White matter hyperintensities in diverse populations: A systematic review of literature in the United States. Cereb Circ Cogn Behav. 2024; 6:100204.
Farkhondeh V, DeCarli C. PMID: 38298455; PMCID: PMC10828602.
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PubMed Mentions:
1
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Hypertension, Cognitive Decline, and Mild Cognitive Impairment Among Diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging Results (SOL-INCA). J Alzheimers Dis. 2024; 97(3):1449-1461.
Márquez F, Tarraf W, Stickel AM, González KA, Testai FD, Cai J, Gallo LC, Talavera GA, Daviglus ML, Wassertheil-Smoller S, DeCarli C, Schneiderman N, González HM. PMID: 38250769.
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Humans
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Association of Loneliness with Functional Connectivity MRI, Amyloid-β PET, and Tau PET Neuroimaging Markers of Vulnerability for Alzheimer's Disease. J Alzheimers Dis. 2024; 99(4):1473-1484.
Zhao A, Balcer LJ, Himali JJ, O'Donnell A, Rahimpour Y, DeCarli C, Gonzales MM, Aparicio HJ, Ramos-Cejudo J, Kenney R, Beiser A, Seshadri S, Salinas J. PMID: 38820017; PMCID: PMC11191473.
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Humans
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Associations of Physical Activity Engagement with Cerebral Amyloid-β and Tau from Midlife. J Alzheimers Dis. 2024; 100(3):935-943.
Gonzales MM, Kojis D, Spartano NL, Thibault EG, DeCarli CS, El Fakhri G, Johnson KA, Beiser AS, Seshadri S. PMID: 39031362.
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Humans
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Non-invasive quantification of 18F-florbetaben with total-body EXPLORER PET. Res Sq. 2023 Dec 27.
Holy EN, Li E, Bhattarai A, Fletcher E, Alfaro ER, Harvey DJ, Spencer BA, Cherry SR, DeCarli CS, Fan AP. PMID: 38234716; PMCID: PMC10793501.
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A novel neuroimaging signature for ADRD risk stratification in the community. Alzheimers Dement. 2024 03; 20(3):1881-1893.
Satizabal CL, Beiser AS, Fletcher E, Seshadri S, DeCarli C. PMID: 38147416; PMCID: PMC10984488.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Association of Sleep Duration and Change Over Time With Imaging Biomarkers of Cerebrovascular, Amyloid, Tau, and Neurodegenerative Pathology. Neurology. 2024 Jan 09; 102(1):e207807.
Baril AA, Kojis DJ, Himali JJ, Decarli CS, Sanchez E, Johnson KA, El Fakhri G, Thibault E, Yiallourou SR, Himali D, Cavuoto MG, Pase MP, Beiser AS, Seshadri S. PMID: 38165370; PMCID: PMC10834132.
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1 Fields:
Translation:
Humans
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Association Between Slow-Wave Sleep Loss and Incident Dementia. JAMA Neurol. 2023 12 01; 80(12):1326-1333.
Himali JJ, Baril AA, Cavuoto MG, Yiallourou S, Wiedner CD, Himali D, DeCarli C, Redline S, Beiser AS, Seshadri S, Pase MP. PMID: 37902739; PMCID: PMC10616771.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts. Neuroimage Clin. 2023; 40:103547.
Coenen M, Biessels GJ, DeCarli C, Fletcher EF, Maillard PM, Alzheimer's Disease Neuroimaging Initiative, Barkhof F, Barnes J, Benke T, Boomsma JMF, P L H Chen C, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Xin X, Biesbroek JM, Kuijf HJ. PMID: 38035457; PMCID: PMC10698002.
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1 Fields:
Translation:
Humans
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Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus. Clin Epigenetics. 2023 10 27; 15(1):173.
Sarnowski C, Huan T, Ma Y, Joehanes R, Beiser A, DeCarli CS, Heard-Costa NL, Levy D, Lin H, Liu CT, Liu C, Meigs JB, Satizabal CL, Florez JC, Hivert MF, Dupuis J, De Jager PL, Bennett DA, Seshadri S, Morrison AC. PMID: 37891690; PMCID: PMC10612362.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort. Hypertension. 2024 Jan; 81(1):87-95.
Petrea RE, Pinheiro A, Demissie S, Ekenze O, Aparicio HJ, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S, Lioutas VA, Rafael Romero J. PMID: 37855140; PMCID: PMC10896002.
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Humans
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Sleep duration and brain MRI measures: Results from the SOL-INCA MRI study. Alzheimers Dement. 2024 01; 20(1):641-651.
González KA, Tarraf W, Stickel AM, Kaur S, Agudelo C, Redline S, Gallo LC, Isasi CR, Cai J, Daviglus ML, Testai FD, DeCarli C, González HM, Ramos AR. PMID: 37772658; PMCID: PMC10840814.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Timing and level of educational attainment and late-life cognition in the KHANDLE study. Alzheimers Dement. 2024 01; 20(1):593-600.
Soh Y, Whitmer RA, Whitmer RA, Mayeda ER, Glymour MM, Eng CW, Peterson RL, George KM, Chen R, Quesenberry CP, Mungas DM, DeCarli CS, Gilsanz P. PMID: 37751937; PMCID: PMC10842991.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Relation of MRI-Visible Perivascular Spaces and Other MRI Markers of Cerebral Small Vessel Disease. Brain Sci. 2023 Sep 14; 13(9).
Rodriguez Lara F, Toro AR, Pinheiro A, Demissie S, Ekenze O, Martinez O, Parva P, Charidimou A, Ghosh S, DeCarli C, Seshadri S, Habes M, Maillard P, Romero JR. PMID: 37759924; PMCID: PMC10527297.
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PubMed Mentions:
2
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The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury. Alzheimers Res Ther. 2023 09 12; 15(1):154.
Vered S, Beiser AS, Sulimani L, Sznitman S, Gonzales MM, Aparicio HJ, DeCarli C, Scott MR, Ghosh S, Lewitus GM, Meiri D, Seshadri S, Weinstein G. PMID: 37700370; PMCID: PMC10496329.
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Humans
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A polygenic risk score for Alzheimer's disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S. Alzheimers Res Ther. 2023 08 30; 15(1):146.
Sofer T, Kurniansyah N, Granot-Hershkovitz E, Goodman MO, Tarraf W, Broce I, Lipton RB, Daviglus M, Lamar M, Wassertheil-Smoller S, Cai J, DeCarli CS, Gonzalez HM, Fornage M. PMID: 37649099; PMCID: PMC10469805.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study. Sci Rep. 2023 08 21; 13(1):13622.
Fongang B, Satizabal C, Kautz TF, Wadop YN, Muhammad JAS, Vasquez E, Mathews J, Gireud-Goss M, Saklad AR, Himali J, Beiser A, Cavazos JE, Mahaney MC, Maestre G, DeCarli C, Shipp EL, Vasan RS, Seshadri S. PMID: 37604954; PMCID: PMC10442369.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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MISPEL: A supervised deep learning harmonization method for multi-scanner neuroimaging data. Med Image Anal. 2023 10; 89:102926.
Torbati ME, Minhas DS, Laymon CM, Maillard P, Wilson JD, Chen CL, Crainiceanu CM, DeCarli CS, Hwang SJ, Tudorascu DL. PMID: 37595405; PMCID: PMC10529705.
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1 Fields:
Translation:
Humans
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Cardiovascular health and cognitive outcomes: Findings from a biracial population-based study in the United States. Alzheimers Dement. 2023 Oct; 19(10):4446-4453.
Dhana A, DeCarli CS, Dhana K, Desai P, Holland TM, Evans DA, Rajan KB. PMID: 37534894; PMCID: PMC10592212.
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The complex pathway between amyloid β and cognition: implications for therapy. Lancet Neurol. 2023 09; 22(9):847-857.
Jagust WJ, Teunissen CE, DeCarli C. PMID: 37454670.
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3 Fields:
Translation:
Humans
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Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, et al. PMID: 37461624; PMCID: PMC10350126.
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2
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The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease. Acta Neuropathol Commun. 2023 06 29; 11(1):105.
Scalco R, Saito N, Beckett L, Nguyen ML, Huie E, Wang HP, Flaherty DA, Honig LS, DeCarli C, Rissman RA, Teich AF, Jin LW, Dugger BN. PMID: 37386610; PMCID: PMC10311731.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels. Commun Biol. 2023 06 24; 6(1):668.
Wong DR, Magaki SD, Vinters HV, Yong WH, Monuki ES, Williams CK, Martini AC, DeCarli C, Khacherian C, Graff JP, Dugger BN, Keiser MJ. PMID: 37355729; PMCID: PMC10290693.
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PubMed Mentions:
1 Translation:
Humans
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Clinical trials in vascular cognitive impairment following SPRINT-MIND: An international perspective. Cell Rep Med. 2023 06 20; 4(6):101089.
Elahi FM, Alladi S, Black SE, Claassen JAHR, DeCarli C, Hughes TM, Moonen J, Pajewski NM, Price BR, Satizabal C, Shaaban CE, Silva NCBS, Snyder HM, Sveikata L, Williamson JD, Wolters FJ, Hainsworth AH. PMID: 37343515; PMCID: PMC10314118.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurol. 2023 07; 22(7):602-618.
Duering M, Biessels GJ, Brodtmann A, Chen C, Cordonnier C, de Leeuw FE, Debette S, Frayne R, Jouvent E, Rost NS, Ter Telgte A, Al-Shahi Salman R, Backes WH, Bae HJ, Brown R, Chabriat H, De Luca A, deCarli C, Dewenter A, Doubal FN, Ewers M, Field TS, Ganesh A, Greenberg S, Helmer KG, Hilal S, Jochems ACC, Jokinen H, Kuijf H, Lam BYK, Lebenberg J, MacIntosh BJ, Maillard P, Mok VCT, Pantoni L, Rudilosso S, Satizabal CL, Schirmer MD, Schmidt R, Smith C, Staals J, Thrippleton MJ, van Veluw SJ, Vemuri P, Wang Y, Werring D, Zedde M, Akinyemi RO, Del Brutto OH, Markus HS, Zhu YC, Smith EE, Dichgans M, Wardlaw JM. PMID: 37236211.
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PubMed Mentions:
87 Fields:
Translation:
Humans
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Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment. Transl Psychiatry. 2023 04 29; 13(1):140.
Granot-Hershkovitz E, Spitzer B, Yang Y, Tarraf W, Yu B, Boerwinkle E, Fornage M, Mosley TH, DeCarli C, Kristal BS, González HM, Sofer T. PMID: 37120436; PMCID: PMC10148805.
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Humans
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Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers. Stroke. 2023 05; 54(5):1227-1235.
Sapkota S, Erickson K, Fletcher E, Tomaszewski Farias SE, Jin LW, DeCarli C, Alzheimer’s Disease Neuroimaging Initiative*. PMID: 37021572; PMCID: PMC10121244.
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Humans
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Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers. JAMA Netw Open. 2023 04 03; 6(4):e236431.
George KM, Maillard P, Gilsanz P, Fletcher E, Peterson RL, Fong J, Mayeda ER, Mungas DM, Barnes LL, Glymour MM, DeCarli C, Whitmer RA, Whitmer RA. PMID: 37010868; PMCID: PMC10071343.
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1 Fields:
Translation:
Humans
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Association of Left Atrial Strain With Ischemic Stroke Risk in Older Adults. JAMA Cardiol. 2023 04 01; 8(4):317-325.
Mannina C, Ito K, Jin Z, Yoshida Y, Matsumoto K, Shames S, Russo C, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Homma S, Sacco RL, Di Tullio MR. PMID: 36753086; PMCID: PMC9909576.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Interaction analysis of ancestry-enriched variants with APOE-ɛ4 on MCI in the Study of Latinos-Investigation of Neurocognitive Aging. Sci Rep. 2023 03 29; 13(1):5114.
Granot-Hershkovitz E, Xia R, Yang Y, Spitzer B, Tarraf W, Vásquez PM, Lipton RB, Daviglus M, Argos M, Cai J, Kaplan R, Fornage M, DeCarli C, Gonzalez HM, Sofer T. PMID: 36991100; PMCID: PMC10060219.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Subclinical left ventricular systolic dysfunction and incident stroke in the elderly: long-term findings from Cardiovascular Abnormalities and Brain Lesions. Eur Heart J Cardiovasc Imaging. 2023 03 21; 24(4):522-531.
Yoshida Y, Jin Z, Russo C, Homma S, Nakanishi K, Ito K, Mannina C, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 35900282; PMCID: PMC10226754.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Toward a statistical validation of brain signatures as robust measures of behavioral substrates. Hum Brain Mapp. 2023 06 01; 44(8):3094-3111.
Fletcher E, Farias S, DeCarli C, Gavett B, Widaman K, De Leon F, Mungas D. PMID: 36939069; PMCID: PMC10171525.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts. Neurology. 2023 05 02; 100(18):e1930-e1943.
Zhang Y, Liu X, Wiggins KL, Kurniansyah N, Guo X, Rodrigue AL, Zhao W, Yanek LR, Ratliff SM, Pitsillides A, Aguirre Patiño JS, Sofer T, Arking DE, Austin TR, Beiser AS, Blangero J, Boerwinkle E, Bressler J, Curran JE, Hou L, Hughes TM, Kardia SLR, Launer LJ, Levy D, Mosley TH, Nasrallah IM, Rich SS, Rotter JI, Seshadri S, Tarraf W, González KA, Ramachandran V, Yaffe K, Nyquist PA, Psaty BM, DeCarli CS, Smith JA, Glahn DC, González HM, Bis JC, Fornage M, Heckbert SR, Fitzpatrick AL, Liu C, Satizabal CL, NHLBI Trans-Omics for Precision Medicine (TOPMed) program, Mitochondrial and Neurocognitive Working . PMID: 36927883; PMCID: PMC10159770.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Inflammatory biomarkers and MRI visible perivascular spaces: The Framingham Heart Study. Neurobiol Aging. 2023 07; 127:12-22.
Ekenze O, Pinheiro A, Demissie S, Charidimou A, Beiser AS, Vasan RS, Benjamin EJ, DeCarli C, Seshadri S, Romero JR. PMID: 37018882; PMCID: PMC10198814.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Assessing cognitive impairment in an ethnically diverse cohort of oldest-old: the life after 90 study. Aging Clin Exp Res. 2023 May; 35(5):979-986.
Petrosyan D, Corrada MM, Kawas CH, Demoz A, Ganzon C, Popovich O, Gaied R, Mungas D, Gilsanz P, Vieira KE, Whitmer RA, Whitmer RA, DeCarli C. PMID: 36870029; PMCID: PMC10149459.
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1 Fields:
Translation:
Humans
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Serum neurofilament light chain, brain infarcts, and the risk of stroke: a prospective population-based cohort study. Eur J Epidemiol. 2023 Apr; 38(4):427-434.
Dhana A, DeCarli C, Aggarwal NT, Dhana K, Desai P, Evans DA, Rajan KB. PMID: 36867286; PMCID: PMC10081967.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI). Neurobiol Aging. 2023 06; 126:58-66.
Stickel AM, Tarraf W, González KA, Ivanovic V, Morlett Paredes A, Zeng D, Cai J, Isasi CR, Kaplan R, Lipton RB, Daviglus M, Testai FD, Lamar M, Gallo LC, Talavera GA, Gellman MD, Ramos AR, González HM, DeCarli C. PMID: 36933278; PMCID: PMC10363333.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides. J Neuropathol Exp Neurol. 2023 02 21; 82(3):212-220.
Oliveira LC, Lai Z, Harvey D, Nzenkue K, Jin LW, Decarli C, Chuah CN, Dugger BN. PMID: 36692190; PMCID: PMC9941825.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2023 02 13; 146(2):492-506.
Yang Y, Knol MJ, Wang R, Mishra A, Liu D, Luciano M, Teumer A, Armstrong N, Bis JC, Jhun MA, Li S, Adams HHH, Aziz NA, Bastin ME, Bourgey M, Brody JA, Frenzel S, Gottesman RF, Hosten N, Hou L, Kardia SLR, Lohner V, Marquis P, Maniega SM, Satizabal CL, Sorond FA, Valdés Hernández MC, van Duijn CM, Vernooij MW, Wittfeld K, Yang Q, Zhao W, Boerwinkle E, Levy D, Deary IJ, Jiang J, Mather KA, Mosley TH, Psaty BM, Sachdev PS, Smith JA, Sotoodehnia N, DeCarli CS, Breteler MMB, Ikram MA, Grabe HJ, Wardlaw J, Longstreth WT, Launer LJ, Seshadri S, Debette S, Fornage M. PMID: 35943854; PMCID: PMC9924914.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer's disease (AD) neuropathology: A hypothesis and review. Front Aging Neurosci. 2023; 15:1096206.
Sharp FR, DeCarli CS, Jin LW, Zhan X. PMID: 36845656; PMCID: PMC9950279.
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PubMed Mentions:
8
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Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985. Res Sq. 2023 Jan 30.
DeCarli C, Pase M, Beiser A, Kojis D, Satizabal C, Himali J, Aparicio H, Flether E, Maillard P, Seshadri S. PMID: 36778357; PMCID: PMC9915799.
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PubMed Mentions:
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Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels. bioRxiv. 2023 Jan 17.
Wong DR, Magaki SD, Vinters HV, Yong WH, Monuki ES, Williams CK, Martini AC, DeCarli C, Khacherian C, Graff JP, Dugger BN, Keiser MJ. PMID: 36711704; PMCID: PMC9882138.
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Dual cognitive and mobility impairments and future dementia - Setting a research agenda. Alzheimers Dement. 2023 04; 19(4):1579-1586.
Tian Q, Montero-Odasso M, Buchman AS, Mielke MM, Espinoza S, DeCarli CS, Newman AB, Kritchevsky SB, Rebok GW, Resnick SM, Thambisetty M, Verghese J, Ferrucci L. PMID: 36637077; PMCID: PMC10101877.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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TDP-43 Pathology in the Setting of Intermediate and High Alzheimer's Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups. J Alzheimers Dis. 2023; 91(4):1291-1301.
Huie EZ, Escudero A, Saito N, Harvey D, Nguyen ML, Lucot KL, LaGrande J, Mungas D, DeCarli C, Lamar M, Schneider JA, Kapasi A, Rissman RA, Teich AF, Dugger BN. PMID: 36617779; PMCID: PMC9974776.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Association of MRI Visible Perivascular Spaces and Neurofilament Light Chain: The Framingham Heart Study. J Alzheimers Dis. 2023; 95(3):1133-1145.
Ekenze O, Pinheiro A, Demissie S, Aparicio HJ, Charidimou A, Beiser AS, Satizabal CL, Kautz T, DeCarli C, Greenberg S, Seshadri S, Romero JR. PMID: 37661877; PMCID: PMC11298784.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. J Alzheimers Dis. 2023; 95(2):561-572.
Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS. PMID: 37574733.
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Humans
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Proteome Network Analysis Identifies Potential Biomarkers for Brain Aging. J Alzheimers Dis. 2023; 96(4):1767-1780.
Short MI, Fohner AE, Skjellegrind HK, Beiser A, Gonzales MM, Satizabal CL, Austin TR, Longstreth WT, Bis JC, Lopez O, Hveem K, Selbæk G, Larson MG, Yang Q, Aparicio HJ, McGrath ER, Gerszten RE, DeCarli CS, Psaty BM, Vasan RS, Zare H, Seshadri S. PMID: 38007645; PMCID: PMC10741337.
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Translation:
Humans
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MRI Visible Perivascular Spaces and the Risk of Incident Mild Cognitive Impairment in a Community Sample. J Alzheimers Dis. 2023; 96(1):103-112.
Pase MP, Pinheiro A, Rowsthorn E, Demissie S, Hurmez S, Aparicio HJ, Rodriguez-Lara F, Gonzales MM, Beiser A, DeCarli C, Seshadri S, Romero JR. PMID: 37742645; PMCID: PMC10846532.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol. J Alzheimers Dis. 2023; 96(2):683-693.
Bahrani AA, Abner EL, DeCarli CS, Barber JM, Sutton AC, Maillard P, Sandoval F, Arfanakis K, Yang YC, Evia AM, Schneider JA, Habes M, Franklin CG, Seshadri S, Satizabal CL, Caprihan A, Thompson JF, Rosenberg GA, Wang DJJ, Jann K, Zhao C, Lu H, Rosenberg PB, Albert MS, Ali DG, Singh H, Schwab K, Greenberg SM, Helmer KG, Powel DK, Gold BT, Goldstein LB, Wilcock DM, Jicha GA. PMID: 37840499; PMCID: PMC11009792.
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Humans
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White matter hyperintensity, neurofilament light chain, and cognitive decline. Ann Clin Transl Neurol. 2023 03; 10(3):321-327.
Dhana A, DeCarli C, Dhana K, Desai P, Wilson RS, Evans DA, Rajan KB. PMID: 36542548; PMCID: PMC10014007.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury. Cell Rep. 2022 12 20; 41(12):111848.
Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, Sheth SA, Williams CK, Zhang XR, Macknicki M, Brumm A, Kawaguchi R, Mai P, Kaneko N, Vinters HV, Carmichael ST, Havton LA, DeCarli C, Hinman JD. PMID: 36543124; PMCID: PMC10026849.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium. Alzheimers Dement (Amst). 2022; 14(1):e12362.
Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, Singh H, Schwab K, Helmer KG, Greenberg SM, DeCarli C, Caprihan A. PMID: 36523847; PMCID: PMC9745638.
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PubMed Mentions:
4
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Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients. Alzheimers Dement. 2023 06; 19(6):2420-2432.
Coenen M, Kuijf HJ, Huenges Wajer IMC, Duering M, Wolters FJ, Fletcher EF, Maillard PM, Alzheimer's Disease Neuroimaging Initiative, Barkhof F, Barnes J, Benke T, Boomsma JMF, Chen CPLH, Dal-Bianco P, Dewenter A, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek DL, Maier AB, McCreary CR, Padilla CS, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Steketee RME, Sudre CH, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Xin X, DeCarli C, Biessels GJ, Biesbroek JM. PMID: 36504357.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Genetic associations between sleep traits and cognitive ageing outcomes in the Hispanic Community Health Study/Study of Latinos. EBioMedicine. 2023 Jan; 87:104393.
Zhang Y, Elgart M, Granot-Hershkovitz E, Wang H, Tarraf W, Ramos AR, Stickel AM, Zeng D, Garcia TP, Testai FD, Wassertheil-Smoller S, Isasi CR, Daviglus ML, Kaplan R, Fornage M, DeCarli C, Redline S, González HM, Sofer T. PMID: 36493726; PMCID: PMC9732133.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study. Neurology. 2022 Dec 05; 99(23):e2561-e2571.
Romero JR, Pinheiro A, Aparicio HJ, DeCarli CS, Demissie S, Seshadri S. PMID: 36175148; PMCID: PMC9754649.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study. Neurology. 2022 Dec 05; 99(23):e2572-e2582.
Satizabal CL, Himali JJ, Beiser AS, Ramachandran V, Melo van Lent D, Himali D, Aparicio HJ, Maillard P, DeCarli CS, Harris WS, Seshadri S. PMID: 36198518; PMCID: PMC9754651.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Longitudinal Changes in Blood Biomarkers of Clinical Alzheimer Disease in a Biracial Population Sample. Neurology. 2023 02 21; 100(8):e874-e883.
Rajan KB, McAninch EA, Aggarwal NT, Barnes LL, Wilson RS, Weuve J, DeCarli CS, Evans DA. PMID: 36446595; PMCID: PMC9984218.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Optimizing quantification of MK6240 tau PET in unimpaired older adults. Neuroimage. 2023 01; 265:119761.
Harrison TM, Ward TJ, Murphy A, Baker SL, Dominguez PA, Koeppe R, Vemuri P, Lockhart SN, Jung Y, Harvey DJ, Lovato L, Toga AW, Masdeu J, Oh H, Gitelman DR, Aggarwal N, Snyder HM, Baker LD, DeCarli C, Jagust WJ, Landau SM, U.S. POINTER Study Group. PMID: 36455762; PMCID: PMC9957642.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study. Front Cardiovasc Med. 2022; 9:1013876.
Cooper LL, Rong J, Maillard P, Beiser A, Hamburg NM, Larson MG, DeCarli C, Vasan RS, Seshadri S, Mitchell GF. PMID: 36386360; PMCID: PMC9663798.
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Self-reported sleepiness associates with greater brain and cortical volume and lower prevalence of ischemic covert brain infarcts in a community sample. Sleep. 2022 10 10; 45(10).
Baril AA, Beiser AS, DeCarli C, Himali D, Sanchez E, Cavuoto M, Redline S, Gottlieb DJ, Seshadri S, Pase MP, Himali JJ. PMID: 35917199; PMCID: PMC9548673.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition. Alzheimers Dement. 2023 04; 19(4):1331-1342.
Granot-Hershkovitz E, He S, Bressler J, Yu B, Tarraf W, Rebholz CM, Cai J, Chan Q, Garcia TP, Mosley T, Kristal BS, DeCarli C, Fornage M, Chen GC, Qi Q, Kaplan R, González HM, Sofer T. PMID: 36111689; PMCID: PMC10017373.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Progression of cerebral white matter hyperintensities is related to leucocyte gene expression. Brain. 2022 09 14; 145(9):3179-3186.
Jickling GC, Ander BP, Zhan X, Stamova B, Hull H, DeCarli C, Sharp FR. PMID: 35325079; PMCID: PMC10233292.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Interaction between Alzheimer's Disease and Cerebral Small Vessel Disease: A Review Focused on Neuroimaging Markers. Int J Mol Sci. 2022 Sep 10; 23(18).
Kim SE, Kim HJ, Jang H, Weiner MW, DeCarli C, Na DL, Seo SW. PMID: 36142419; PMCID: PMC9499680.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study. EClinicalMedicine. 2022 Nov; 53:101643.
Tao Q, Akhter-Khan SC, Ang TFA, DeCarli C, Alosco ML, Mez J, Killiany R, Devine S, Rokach A, Itchapurapu IS, Zhang X, Lunetta KL, Steffens DC, Farrer LA, Greve DN, Au R, Qiu WQ. PMID: 36105871; PMCID: PMC9465265.
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PubMed Mentions:
7
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A population-based meta-analysis of circulating GFAP for cognition and dementia risk. Ann Clin Transl Neurol. 2022 10; 9(10):1574-1585.
Gonzales MM, Wiedner C, Wang CP, Liu Q, Bis JC, Li Z, Himali JJ, Ghosh S, Thomas EA, Parent DM, Kautz TF, Pase MP, Aparicio HJ, Djoussé L, Mukamal KJ, Psaty BM, Longstreth WT, Mosley TH, Gudnason V, Mbangdadji D, Lopez OL, Yaffe K, Sidney S, Bryan RN, Nasrallah IM, DeCarli CS, Beiser AS, Launer LJ, Fornage M, Tracy RP, Seshadri S, Satizabal CL. PMID: 36056631; PMCID: PMC9539381.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimers Dement (Amst). 2022; 14(1):e12349.
Sapkota S, Erickson K, Harvey D, Tomaszewski-Farias SE, Olichney JM, Johnson DK, Dugger BN, Mungas DM, Fletcher E, Maillard P, Seshadri S, Satizabal CL, Kautz T, Parent D, Tracy RP, Maezawa I, Jin LW, DeCarli C. PMID: 36092690; PMCID: PMC9434579.
View in:
PubMed Mentions:
6
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Assessment of Current Practices Across Alzheimer's Disease Research Centers Biorepositories. Biopreserv Biobank. 2023 Jun; 21(3):282-287.
Lucot KL, Suarez W, Mifflin K, DeCarli C, La Grande J, Dugger BN. PMID: 35856794; PMCID: PMC10282793.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces. Aging (Albany NY). 2022 07 15; 14(17):6844-6858.
Lara FR, Scruton AL, Pinheiro A, Demissie S, Parva P, Charidimou A, Francis M, Himali JJ, DeCarli C, Beiser A, Seshadri S, Romero JR. PMID: 35852852; PMCID: PMC9512514.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain. 2022 06 30; 145(6):1992-2007.
Mishra A, Duplaà C, Vojinovic D, Suzuki H, Sargurupremraj M, Zilhão NR, Li S, Bartz TM, Jian X, Zhao W, Hofer E, Wittfeld K, Harris SE, van der Auwera-Palitschka S, Luciano M, Bis JC, Adams HHH, Satizabal CL, Gottesman RF, Gampawar PG, Bülow R, Weiss S, Yu M, Bastin ME, Lopez OL, Vernooij MW, Beiser AS, Völker U, Kacprowski T, Soumare A, Smith JA, Knopman DS, Morris Z, Zhu Y, Rotter JI, Dufouil C, Valdés Hernández M, Muñoz Maniega S, Lathrop M, Boerwinkle E, Schmidt R, Ihara M, Mazoyer B, Yang Q, Joutel A, Tournier-Lasserve E, Launer LJ, Deary IJ, Mosley TH, Amouyel P, DeCarli CS, Psaty BM, Tzourio C, Kardia SLR, Grabe HJ, Teumer A, van Duijn CM, Schmidt H, Wardlaw JM, Ikram MA, Fornage M, Gudnason V, Seshadri S, Matthews PM, Longstreth WT, Couffinhal T, Debette S. PMID: 35511193; PMCID: PMC9255380.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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High-Density Lipoprotein Changes in Alzheimer's Disease Are APOE Genotype-Specific. Biomedicines. 2022 Jun 24; 10(7).
Hong BV, Zheng J, Agus JK, Tang X, Lebrilla CB, Jin LW, Maezawa I, Erickson K, Harvey DJ, DeCarli CS, Mungas DM, Olichney JM, Farias ST, Zivkovic AM. PMID: 35884800; PMCID: PMC9312991.
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PubMed Mentions:
9
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Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort. Alzheimers Dement. 2023 02; 19(2):621-631.
Melo Van Lent D, Gokingco H, Short MI, Yuan C, Jacques PF, Romero JR, DeCarli CS, Beiser AS, Seshadri S, Himali JJ, Jacob ME. PMID: 35522830; PMCID: PMC9637238.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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BrainSec: Automated Brain Tissue Segmentation Pipeline for Scalable Neuropathological Analysis. IEEE Access. 2022; 10:49064-49079.
Lai Z, Oliveira LC, Guo R, Xu W, Hu Z, Mifflin K, Decarli C, Cheung SC, Chuah CN, Dugger BN. PMID: 36157332; PMCID: PMC9503016.
View in:
PubMed Mentions:
3
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Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces. Ann Neurol. 2022 07; 92(1):23-31.
Pinheiro A, Demissie S, Scruton A, Charidimou A, Parva P, DeCarli C, Seshadri S, Romero JR. PMID: 35373386; PMCID: PMC9233108.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study). J Med Internet Res. 2022 04 15; 24(4):e34513.
Yuan J, Au R, Karjadi C, Ang TF, Devine S, Auerbach S, DeCarli C, Libon DJ, Mez J, Lin H. PMID: 35436225; PMCID: PMC9055470.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels. Commun Biol. 2022 04 08; 5(1):336.
Sarnowski C, Ghanbari M, Bis JC, Logue M, Fornage M, Mishra A, Ahmad S, Beiser AS, Boerwinkle E, Bouteloup V, Chouraki V, Cupples LA, Damotte V, DeCarli CS, DeStefano AL, Djoussé L, Fohner AE, Franz CE, Kautz TF, Lambert JC, Lyons MJ, Mosley TH, Mukamal KJ, Pase MP, Portilla Fernandez EC, Rissman RA, Satizabal CL, Vasan RS, Yaqub A, Debette S, Dufouil C, Launer LJ, Kremen WS, Longstreth WT, Ikram MA, Seshadri S. PMID: 35396452; PMCID: PMC8993877.
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PubMed Mentions:
7 Translation:
Humans
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Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois. JAMA Netw Open. 2022 04 01; 5(4):e227512.
Dhana A, DeCarli C, Dhana K, Desai P, Krueger K, Evans DA, Rajan KB. PMID: 35426922; PMCID: PMC9012965.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. Alzheimers Dement (Amst). 2022; 14(1):e12261.
Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ, Rosenberg GA, Snoussi H, Sepehrband F, Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Schwab K, Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL, MarkVCID Consortium. PMID: 35382232; PMCID: PMC8959640.
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PubMed Mentions:
23
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Examination of Neurofilament Light Chain Serum Concentrations, Physical Activity, and Cognitive Decline in Older Adults. JAMA Netw Open. 2022 03 01; 5(3):e223596.
Desai P, Dhana K, DeCarli C, Wilson RS, McAninch EA, Evans DA, Rajan KB. PMID: 35315915; PMCID: PMC8941360.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Blood metabolites predicting mild cognitive impairment in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL). Alzheimers Dement (Amst). 2022; 14(1):e12259.
He S, Granot-Hershkovitz E, Zhang Y, Bressler J, Tarraf W, Yu B, Huang T, Zeng D, Wassertheil-Smoller S, Lamar M, Daviglus M, Marquine MJ, Cai J, Mosley T, Kaplan R, Boerwinkle E, Fornage M, DeCarli C, Kristal B, Gonzalez HM, Sofer T. PMID: 35229015; PMCID: PMC8865745.
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PubMed Mentions:
6
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Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline. Neurology. 2022 03 29; 98(13):e1337-e1348.
Salinas J, Beiser AS, Samra JK, O'Donnell A, DeCarli CS, Gonzales MM, Aparicio HJ, Seshadri S. PMID: 35131906; PMCID: PMC8967424.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Measuring Cognitive Health in Ethnically Diverse Older Adults. J Gerontol B Psychol Sci Soc Sci. 2022 02 03; 77(2):261-271.
Hernandez Saucedo H, Whitmer RA, Whitmer RA, Glymour M, DeCarli C, Mayeda ER, Gilsanz P, Miles SQ, Bhulani N, Tomaszewski Farias S, Olichney J, Mungas D. PMID: 33842969; PMCID: PMC8824686.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Accounting for lack of representation in dementia research: Generalizing KHANDLE study findings on the prevalence of cognitive impairment to the California older population. Alzheimers Dement. 2022 11; 18(11):2209-2217.
Hayes-Larson E, Mobley TM, Mungas D, Seamans MJ, Glymour MM, Gilsanz P, DeCarli C, Whitmer RA, Whitmer RA, Mayeda ER. PMID: 35102726; PMCID: PMC9339583.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2022 Feb 01; 12(1):2008.
Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 35105918; PMCID: PMC8807814.
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PubMed Mentions: Fields:
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Imaging Markers of Vascular Brain Health: Quantification, Clinical Implications, and Future Directions. Stroke. 2022 02; 53(2):416-426.
Vemuri P, Decarli C, Duering M. PMID: 35000423; PMCID: PMC8830603.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study. J Alzheimers Dis. 2022; 86(4):1603-1609.
Jacobs HIL, O'Donnell A, Satizabal CL, Lois C, Kojis D, Hanseeuw BJ, Thibault E, Sanchez JS, Buckley RF, Yang Q, DeCarli C, Killiany R, Sargurupremraj M, Sperling RA, Johnson KA, Beiser AS, Seshadri S. PMID: 35213372; PMCID: PMC9038711.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study. J Alzheimers Dis. 2022; 86(3):1371-1383.
Weinstein G, O'Donnell A, Davis-Plourde K, Zelber-Sagi S, Ghosh S, DeCarli CS, Thibault EG, Sperling RA, Johnson KA, Beiser AS, Seshadri S. PMID: 35213373; PMCID: PMC11323287.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Plasma EFEMP1 Is Associated with Brain Aging and Dementia: The Framingham Heart Study. J Alzheimers Dis. 2022; 85(4):1657-1666.
McGrath ER, Himali JJ, Levy D, Yang Q, DeCarli CS, Courchesne P, Satizabal CL, Finney R, Vasan RS, Beiser AS, Seshadri S. PMID: 34958018.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults. J Alzheimers Dis. 2022; 88(1):311-322.
Wittfeld K, Raman MR, Conner SC, Aslam A, Teumer A, Nauck M, Hosten N, Habes M, DeCarli C, Vasan RS, Beiser AS, Himali JJ, Seshadri S, Grabe HJ, Satizabal CL. PMID: 35599493; PMCID: PMC9472289.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden. J Alzheimers Dis. 2022; 89(1):223-232.
Baradaran H, Peloso GM, Polak JF, Killiany RJ, Ghosh S, DeCarli CS, Thibault EG, Sperling RA, Johnson KA, Beiser A, Romero JR, Seshadri S. PMID: 35871328; PMCID: PMC11371395.
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PubMed Mentions: Fields:
Translation:
Humans
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Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis. J Alzheimers Dis. 2022; 90(3):1073-1083.
Frenzel S, Bis JC, Gudmundsson EF, O'Donnell A, Simino J, Yaqub A, Bartz TM, Brusselle GGO, Bülow R, DeCarli CS, Ewert R, Gharib SA, Ghosh S, Gireud-Goss M, Gottesman RF, Ikram MA, Knopman DS, Launer LJ, London SJ, Longstreth WT, Lopez OL, Melo van Lent D, O'Connor G, Satizabal CL, Shrestha S, Sigurdsson S, Stubbe B, Talluri R, Vasan RS, Vernooij MW, Völzke H, Wiggins KL, Yu B, Beiser AS, Gudnason V, Mosley T, Psaty BM, Wolters FJ, Grabe HJ, Seshadri S. PMID: 36213999; PMCID: PMC9712227.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias. Alzheimers Dement (Amst). 2021; 13(1):e12265.
Mungas D, Shaw C, Hayes-Larson E, DeCarli C, Farias ST, Olichney J, Saucedo HH, Gilsanz P, Glymour MM, Whitmer RA, Whitmer RA, Mayeda ER. PMID: 35005198; PMCID: PMC8719430.
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PubMed Mentions:
7
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Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community. Hypertension. 2022 03; 79(3):505-515.
Vasan RS, Song RJ, Xanthakis V, Beiser A, DeCarli C, Mitchell GF, Seshadri S. PMID: 35138872; PMCID: PMC8849561.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Multi-scanner Harmonization of Paired Neuroimaging Data via Structure Preserving Embedding Learning. IEEE Int Conf Comput Vis Workshops. 2021 Oct; 2021:3277-3286.
Torbati ME, Tudorascu DL, Minhas DS, Maillard P, DeCarli CS, Hwang SJ. PMID: 34909551; PMCID: PMC8668020.
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PubMed Mentions:
3
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The link between blood pressure and Alzheimer's disease. Lancet Neurol. 2021 11; 20(11):878-879.
DeCarli C. PMID: 34687619.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 06; 7(6):616-628.
Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumaré A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli C, Fletcher E, Paus T, Lathrop M, Adams HHH, Bis JC, Seshadri S, Tzourio C, Mazoyer B, Debette S. PMID: 34700051; PMCID: PMC9395126.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Frontal white matter lesions in Alzheimer's disease are associated with both small vessel disease and AD-associated cortical pathology. Acta Neuropathol. 2021 12; 142(6):937-950.
McAleese KE, Miah M, Graham S, Hadfield GM, Walker L, Johnson M, Colloby SJ, Thomas AJ, DeCarli C, Koss D, Attems J. PMID: 34608542; PMCID: PMC8568857.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Bone Mineral Density Measurements and Association With Brain Structure and Cognitive Function: The Framingham Offspring Cohort. Alzheimer Dis Assoc Disord. 2021 Oct-Dec 01; 35(4):291-297.
Stefanidou M, O'Donnell A, Himali JJ, DeCarli C, Satizabal C, Beiser AS, Seshadri S, Zaldy T. PMID: 33973881; PMCID: PMC8608007.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease. Alzheimers Dement. 2022 04; 18(4):824-857.
Veitch DP, Weiner MW, Aisen PS, Beckett LA, DeCarli C, Green RC, Harvey D, Jack CR, Jagust W, Landau SM, Morris JC, Okonkwo O, Perrin RJ, Petersen RC, Rivera-Mindt M, Saykin AJ, Shaw LM, Toga AW, Tosun D, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative. PMID: 34581485; PMCID: PMC9158456.
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PubMed Mentions:
39 Fields:
Translation:
Humans
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Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort. Front Med (Lausanne). 2021; 8:671945.
Lau WL, Fisher M, Fletcher E, DeCarli C, Troutt H, Corrada MM, Kawas C, Paganini-Hill A. PMID: 34616751; PMCID: PMC8488112.
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PubMed Mentions:
5
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Stroke Belt birth state and late-life cognition in the Study of Healthy Aging in African Americans (STAR). Ann Epidemiol. 2021 12; 64:26-32.
George KM, Peterson RL, Gilsanz P, Barnes LL, Mayeda ER, Glymour MM, Mungas DM, DeCarli CS, Whitmer RA, Whitmer RA. PMID: 34509621; PMCID: PMC8629938.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Impact of Cardiovascular Risk Factors in Adolescence, Young Adulthood, and Midlife on Late-Life Cognition: Study of Healthy Aging in African Americans. J Gerontol A Biol Sci Med Sci. 2021 08 13; 76(9):1692-1698.
George KM, Gilsanz P, Peterson RL, Barnes LL, DeCarli CS, Mayeda ER, Mungas DM, Whitmer RA, Whitmer RA. PMID: 34387334; PMCID: PMC8361347.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. Sci Rep. 2021 08 10; 11(1):16198.
Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ. PMID: 34376699; PMCID: PMC8355229.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Association of Social Support With Brain Volume and Cognition. JAMA Netw Open. 2021 08 02; 4(8):e2121122.
Salinas J, O'Donnell A, Kojis DJ, Pase MP, DeCarli C, Rentz DM, Berkman LF, Beiser A, Seshadri S. PMID: 34398201; PMCID: PMC8369356.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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The latent factor structure underlying regional brain volume change and its relation to cognitive change in older adults. Neuropsychology. 2021 Sep; 35(6):643-655.
Gavett BE, Fletcher E, Widaman KF, Tomaszewski Farias S, DeCarli C, Mungas D. PMID: 34292026; PMCID: PMC8501944.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Prevalence of incidental brain MRI findings of clinical relevance in a diverse Hispanic/Latino population. J Neuroimaging. 2021 11; 31(6):1166-1175.
Ivanovic V, Seiler S, Tarraf W, Crivello E, Martinez O, Lipton RB, Isasi CR, Copello TG, Talavera GA, Gallo LC, Lamar M, Testai F, Schneiderman N, Gellman MD, Daviglus M, Gonzalez HM, DeCarli C, Lipton ML. PMID: 34288226; PMCID: PMC10332335.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Coronary Artery Calcium Assessed Years Before Was Positively Associated With Subtle White Matter Injury of the Brain in Asymptomatic Middle-Aged Men: The Framingham Heart Study. Circ Cardiovasc Imaging. 2021 07; 14(7):e011753.
Suzuki H, Davis-Plourde K, Beiser A, Kunimura A, Miura K, DeCarli C, Maillard P, Mitchell GF, Vasan RS, Seshadri S, Fujiyoshi A. PMID: 34256573; PMCID: PMC8323993.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Neighborhood racial/ethnic segregation and cognitive decline in older adults. Soc Sci Med. 2021 09; 284:114226.
Meyer OL, Besser L, Mitsova D, Booker M, Luu E, Tobias M, Farias ST, Mungas D, DeCarli C, Whitmer RA, Whitmer RA. PMID: 34303293; PMCID: PMC8656323.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Digital sleep measures and white matter health in the Framingham Heart Study. Explor Med. 2021; 2(3):253-267.
Thomas RJ, Kim H, Maillard P, DeCarli CS, Heckman EJ, Karjadi C, Ang TFA, Au R. PMID: 34927164; PMCID: PMC8682916.
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PubMed Mentions:
6
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Convolutional Neural Net Learning Can Achieve Production-Level Brain Segmentation in Structural Magnetic Resonance Imaging. Front Neurosci. 2021; 15:683426.
Fletcher E, DeCarli C, Fan AP, Knaack A. PMID: 34234642; PMCID: PMC8255694.
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PubMed Mentions:
8
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Amyloid-PET imaging offers small improvements in predictions of future cognitive trajectories. Neuroimage Clin. 2021; 31:102713.
Ackley SF, Hayes-Larson E, Brenowitz WD, Swinnerton K, Mungas D, Fletcher E, Singh B, Whitmer RA, Whitmer RA, DeCarli C, Maria Glymour M. PMID: 34153689; PMCID: PMC8233225.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Alzheimers Dement. 2021 10; 17(10):1663-1674.
Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C, Knol MJ, Li S, Schraen S, Grove ML, Satizabal C, Amin N, Berr C, Younkin S, Alzheimer's Disease Neuroimaging Initiative, Gottesman RF, Buée L, Beiser A, Knopman DS, Uitterlinden A, DeCarli C, Bressler J, DeStefano A, Dartigues JF, Yang Q, Boerwinkle E, Tzourio C, Fornage M, Ikram MA, Amouyel P, de Jager P, Reitz C, Mosley TH, Lambert JC, Seshadri S, van Duijn CM. PMID: 34002480; PMCID: PMC8597077.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
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PubMed Mentions:
9 Fields:
Translation:
Humans
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A robust brain signature region approach for episodic memory performance in older adults. Brain. 2021 05 07; 144(4):1089-1102.
Fletcher E, Gavett B, Crane P, Soldan A, Hohman T, Farias S, Widaman K, Groot C, Renteria MA, Zahodne L, DeCarli C, Mungas D, Alzheimer's Disease Neuroimaging Initiative. PMID: 33895818; PMCID: PMC8105039.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Racial/Ethnic Disparities in Young Adulthood and Midlife Cardiovascular Risk Factors and Late-life Cognitive Domains: The Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study. Alzheimer Dis Assoc Disord. 2021 Apr-Jun 01; 35(2):99-105.
Peterson RL, George KM, Gilsanz P, Ackley S, Mayeda ER, Glymour MM, Mungas DM, DeCarli C, Whitmer RA, Whitmer RA. PMID: 34006727; PMCID: PMC8862715.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Cortical superficial siderosis in the general population: The Framingham Heart and Rotterdam studies. Int J Stroke. 2021 10; 16(7):798-808.
Shoamanesh A, Akoudad S, Himali JJ, Beiser AS, DeCarli C, Seshadri S, Arfan Ikram M, Romero JR, Vernooij MW. PMID: 33478376; PMCID: PMC9822782.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols. Alzheimers Dement. 2021 04; 17(4):716-725.
Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM, MarkVCID Consortium. PMID: 33480157; PMCID: PMC8627001.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Sci Transl Med. 2021 01 20; 13(577).
Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gómez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA. PMID: 33472953; PMCID: PMC7978042.
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PubMed Mentions:
76 Fields:
Translation:
Humans
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Mind Diet Adherence and Cognitive Performance in the Framingham Heart Study. J Alzheimers Dis. 2021; 82(2):827-839.
Melo van Lent D, O'Donnell A, Beiser AS, Vasan RS, DeCarli CS, Scarmeas N, Wagner M, Jacques PF, Seshadri S, Himali JJ, Pase MP. PMID: 34092629.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Race/Ethnic Disparities in Mild Cognitive Impairment and Dementia: The Northern Manhattan Study. J Alzheimers Dis. 2021; 80(3):1129-1138.
Wright CB, DeRosa JT, Moon MP, Strobino K, DeCarli C, Cheung YK, Assuras S, Levin B, Stern Y, Sun X, Rundek T, Elkind MSV, Sacco RL. PMID: 33646162; PMCID: PMC8150441.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 01 01; 78(1):102-113.
Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Writing Group for the Alzheimer’s Disease Genetics Consortium (ADGC), Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. PMID: 33074286; PMCID: PMC7573798.
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PubMed Mentions:
95 Fields:
Translation:
Humans
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Slow-Wave Sleep and MRI Markers of Brain Aging in a Community-Based Sample. Neurology. 2021 03 09; 96(10):e1462-e1469.
Baril AA, Beiser AS, Mysliwiec V, Sanchez E, DeCarli CS, Redline S, Gottlieb DJ, Maillard P, Romero JR, Satizabal CL, Zucker JM, Seshadri S, Pase MP, Himali JJ. PMID: 33361258; PMCID: PMC8055313.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Cerebral small vessel disease genomics and its implications across the lifespan. Nat Commun. 2020 12 08; 11(1):6285.
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Akker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL, Beaudet G, Petit L, Tsuchida A, Zago L, Schilling S, Sigurdsson S, Gottesman RF, Lewis CE, Aggarwal NT, Lopez OL, Smith JA, Valdés Hernández MC, van der Grond J, Wright MJ, Knol MJ, Dörr M, Thomson RJ, Bordes C, Le Grand Q, Duperron MG, Smith AV, Knopman DS, Schreiner PJ, Evans DA, Rotter JI, Beiser AS, Maniega SM, Beekman M, Trollor J, Stott DJ, Vernooij MW, Wittfeld K, Niessen WJ, Soumaré A, Boerwinkle E, Sidney S, Turner ST, Davies G, Thalamuthu A, Völker U, van Buchem MA, Bryan RN, Dupuis J, Bastin ME, Ames D, Teumer A, Amouyel P, Kwok JB, Bülow R, Deary IJ, Schofield PR, Brodaty H, Jiang J, Tabara Y, Setoh K, Miyamoto S, Yoshida K, Nagata M, Kamatani Y, Matsuda F, Psaty BM, Bennett DA, De Jager PL, Mosley TH, Sachdev PS, Schmidt R, Warren HR, Evangelou E, Trégouët DA, International Network against Thrombosis (INVENT) Consortium, International Headache Genomics Consortium (IHGC), Ikram MA, Wen W, DeCarli C, Srikanth VK, Jukema JW, Slagboom EP, Kardia SLR, Okada Y, Mazoyer B, Wardlaw JM, Nyquist PA, Mather KA, Grabe HJ, Schmidt H, Van Duijn CM, Gudnason V, Longstreth WT, Launer LJ, Lathrop M, Seshadri S, Tzourio C, Adams HH, Matthews PM, Fornage M, Debette S. PMID: 33293549; PMCID: PMC7722866.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Diagnostic Accuracy of Amyloid versus 18 F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia. Ann Neurol. 2021 02; 89(2):389-401.
Lesman-Segev OH, La Joie R, Iaccarino L, Lobach I, Rosen HJ, Seo SW, Janabi M, Baker SL, Edwards L, Pham J, Olichney J, Boxer A, Huang E, Gorno-Tempini M, DeCarli C, Hepker M, Hwang JL, Miller BL, Spina S, Grinberg LT, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 33219525; PMCID: PMC7856004.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL). Alzheimers Dement. 2021 03; 17(3):466-474.
Granot-Hershkovitz E, Tarraf W, Kurniansyah N, Daviglus M, Isasi CR, Kaplan R, Lamar M, Perreira KM, Wassertheil-Smoller S, Stickel A, Thyagarajan B, Zeng D, Fornage M, DeCarli CS, González HM, Sofer T. PMID: 33155766; PMCID: PMC8016734.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Left Atrial Strain and Subclinical Cerebrovascular Disease in Older Adults. JACC Cardiovasc Imaging. 2021 02; 14(2):508-510.
Mannina C, Tugcu A, Jin Z, Russo C, Matsumoto K, Ito K, Homma S, Elkind MSV, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 33011124; PMCID: PMC8842543.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Remote Blood Biomarkers of Longitudinal Cognitive Outcomes in a Population Study. Ann Neurol. 2020 12; 88(6):1065-1076.
Rajan KB, Aggarwal NT, McAninch EA, Weuve J, Barnes LL, Wilson RS, DeCarli C, Evans DA. PMID: 32799383; PMCID: PMC9186023.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nat Commun. 2020 09 22; 11(1):4796.
Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE, ENIGMA consortium, Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT, Fornage M, Paus T, Debette S, Ikram MA, Schmidt H, Schmidt R, Seshadri S. PMID: 32963231; PMCID: PMC7508833.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Growth Differentiation Factor 15 and NT-proBNP as Blood-Based Markers of Vascular Brain Injury and Dementia. J Am Heart Assoc. 2020 10 20; 9(19):e014659.
McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. PMID: 32921207; PMCID: PMC7792414.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Association between APOE ε2 and Aβ burden in patients with Alzheimer- and vascular-type cognitive impairment. Neurology. 2020 10 27; 95(17):e2354-e2365.
Lee JS, Lee H, Park S, Choe Y, Park YH, Cheon BK, Hahn A, Ossenkoppele R, Kim HJ, Kim S, Yoo H, Jang H, Cho SH, Kim SJ, Kim JP, Jung YH, Park KC, DeCarli C, Weiner MW, Na DL, Seo SW. PMID: 32928967; PMCID: PMC7682916.
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PubMed Mentions:
2 Fields:
Translation:
HumansPHPublic Health
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Association of common genetic variants with brain microbleeds: A genome-wide association study. Neurology. 2020 12 15; 95(24):e3331-e3343.
Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS, Alzheimer's Disease Neuroimaging Initiative. PMID: 32913026; PMCID: PMC7836652.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study. Hypertension. 2020 09; 76(3):707-714.
Petrea RE, O'Donnell A, Beiser AS, Habes M, Aparicio H, DeCarli C, Seshadri S, Romero JR. PMID: 32755403; PMCID: PMC7577565.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory. Neurology. 2020 11 10; 95(19):e2622-e2634.
Han JW, Maillard P, Harvey D, Fletcher E, Martinez O, Johnson DK, Olichney JM, Farias ST, Villeneuve S, Jagust W, Mungas D, DeCarli C. PMID: 32732300; PMCID: PMC7713731.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos. Transl Psychiatry. 2020 07 22; 10(1):245.
Jian X, Sofer T, Tarraf W, Bressler J, Faul JD, Zhao W, Ratliff SM, Lamar M, Launer LJ, Laurie CC, Schneiderman N, Weir DR, Wright CB, Yaffe K, Zeng D, DeCarli C, Mosley TH, Smith JA, González HM, Fornage M. PMID: 32699239; PMCID: PMC7376098.
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PubMed Mentions:
5 Fields:
Translation:
HumansPHPublic Health
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Cognitive reserve and midlife vascular risk: Cognitive and clinical outcomes. Ann Clin Transl Neurol. 2020 08; 7(8):1307-1317.
Soldan A, Pettigrew C, Zhu Y, Wang MC, Gottesman RF, DeCarli C, Albert M, BIOCARD Research Team. PMID: 32856790; PMCID: PMC7448143.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study. Ann Clin Transl Neurol. 2020 07; 7(7):1083-1091.
Romero JR, Demissie S, Beiser A, Himali JJ, DeCarli C, Levy D, Seshadri S. PMID: 32588552; PMCID: PMC7359126.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke. 2020 07; 51(7):2111-2121.
Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA. PMID: 32517579; PMCID: PMC7365038.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Flavonoid Intake and MRI Markers of Brain Health in the Framingham Offspring Cohort. J Nutr. 2020 06 01; 150(6):1545-1553.
Shishtar E, Rogers GT, Blumberg JB, Au R, DeCarli C, Jacques PF. PMID: 32211795; PMCID: PMC7269753.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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The progression of carotid atherosclerosis and imaging markers of dementia. Alzheimers Dement (N Y). 2020; 6(1):e12015.
Baradaran H, Demissie S, Himali JJ, Beiser A, Gupta A, Polak JF, DeCarli C, Seshadri S, Romero JR. PMID: 32296732; PMCID: PMC7154591.
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PubMed Mentions:
7
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The genetic architecture of the human cerebral cortex. Science. 2020 03 20; 367(6484).
Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR, Bernard M, Brouwer RM, Buimer EEL, Bülow R, Bürger C, Cannon DM, Chakravarty M, Chen Q, Cheung JW, Couvy-Duchesne B, Dale AM, Dalvie S, de Araujo TK, de Zubicaray GI, de Zwarte SMC, den Braber A, Doan NT, Dohm K, Ehrlich S, Engelbrecht HR, Erk S, Fan CC, Fedko IO, Foley SF, Ford JM, Fukunaga M, Garrett ME, Ge T, Giddaluru S, Goldman AL, Green MJ, Groenewold NA, Grotegerd D, Gurholt TP, Gutman BA, Hansell NK, Harris MA, Harrison MB, Haswell CC, Hauser M, Herms S, Heslenfeld DJ, Ho NF, Hoehn D, Hoffmann P, Holleran L, Hoogman M, Hottenga JJ, Ikeda M, Janowitz D, Jansen IE, Jia T, Jockwitz C, Kanai R, Karama S, Kasperaviciute D, Kaufmann T, Kelly S, Kikuchi M, Klein M, Knapp M, Knodt AR, Krämer B, Lam M, Lancaster TM, Lee PH, Lett TA, Lewis LB, Lopes-Cendes I, Luciano M, Macciardi F, Marquand AF, Mathias SR, Melzer TR, Milaneschi Y, Mirza-Schreiber N, Moreira JCV, Mühleisen TW, Müller-Myhsok B, Najt P, Nakahara S, Nho K, Olde Loohuis LM, Orfanos DP, Pearson JF, Pitcher TL, Pütz B, Quidé Y, Ragothaman A, Rashid FM, Reay WR, Redlich R, Reinbold CS, Repple J, Richard G, Riedel BC, Risacher SL, Rocha CS, Mota NR, Salminen L, Saremi A, Saykin AJ, Schlag F, Schmaal L, Schofield PR, Secolin R, Shapland CY, Shen L, Shin J, Shumskaya E, Sønderby IE, Sprooten E, Tansey KE, Teumer A, Thalamuthu A, Tordesillas-Gutiérrez D, Turner JA, Uhlmann A, Vallerga CL, van der Meer D, van Donkelaar MMJ, van Eijk L, van Erp TGM, van Haren NEM, van Rooij D, van Tol MJ, Veldink JH, Verhoef E, Walton E, Wang M, Wang Y, Wardlaw JM, Wen W, Westlye LT, Whelan CD, Witt SH, Wittfeld K, Wolf C, Wolfers T, Wu JQ, Yasuda CL, Zaremba D, Zhang Z, Zwiers MP, Artiges E, Assareh AA, Ayesa-Arriola R, Belger A, Brandt CL, Brown GG, Cichon S, Curran JE, Davies GE, Degenhardt F, Dennis MF, Dietsche B, Djurovic S, Doherty CP, Espiritu R, Garijo D, Gil Y, Gowland PA, Green RC, Häusler AN, Heindel W, Ho BC, Hoffmann WU, Holsboer F, Homuth G, Hosten N, Jack CR, Jang M, Jansen A, Kimbrel NA, Kolskår K, Koops S, Krug A, Lim KO, Luykx JJ, Mathalon DH, Mather KA, Mattay VS, Matthews S, Mayoral Van Son J, McEwen SC, Melle I, Morris DW, Mueller BA, Nauck M, Nordvik JE, Nöthen MM, O'Leary DS, Opel N, Martinot MP, Pike GB, Preda A, Quinlan EB, Rasser PE, Ratnakar V, Reppermund S, Steen VM, Tooney PA, Torres FR, Veltman DJ, Voyvodic JT, Whelan R, White T, Yamamori H, Adams HHH, Bis JC, Debette S, Decarli C, Fornage M, Gudnason V, Hofer E, Ikram MA, Launer L, Longstreth WT, Lopez OL, Mazoyer B, Mosley TH, Roshchupkin GV, Satizabal CL, Schmidt R, Seshadri S, Yang Q, Alzheimer’s Disease Neuroimaging Initiative, CHARGE Consortium, EPIGEN Consortium, IMAGEN Consortium, SYS Consortium, Parkinson’s Progression Markers Initiative, Alvim MKM, Ames D, Anderson TJ, Andreassen OA, Arias-Vasquez A, Bastin ME, Baune BT, Beckham JC, Blangero J, Boomsma DI, Brodaty H, Brunner HG, Buckner RL, Buitelaar JK, Bustillo JR, Cahn W, Cairns MJ, Calhoun V, Carr VJ, Caseras X, Caspers S, Cavalleri GL, Cendes F, Corvin A, Crespo-Facorro B, Dalrymple-Alford JC, Dannlowski U, de Geus EJC, Deary IJ, Delanty N, Depondt C, Desrivières S, Donohoe G, Espeseth T, Fernández G, Fisher SE, Flor H, Forstner AJ, Francks C, Franke B, Glahn DC, et al. PMID: 32193296; PMCID: PMC7295264.
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247 Fields:
Translation:
Humans
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Diabetes, Cognitive Decline, and Mild Cognitive Impairment Among Diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging Results (HCHS/SOL). Diabetes Care. 2020 05; 43(5):1111-1117.
González HM, Tarraf W, González KA, Fornage M, Zeng D, Gallo LC, Talavera GA, Daviglus ML, Lipton RB, Kaplan R, Ramos AR, Lamar M, Cai J, DeCarli C, Schneiderman N. PMID: 32139382; PMCID: PMC7171942.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury. PLoS One. 2020; 15(1):e0227835.
Altendahl M, Maillard P, Harvey D, Cotter D, Walters S, Wolf A, Singh B, Kakarla V, Azizkhanian I, Sheth SA, Xiao G, Fox E, You M, Leng M, Elashoff D, Kramer JH, Decarli C, Elahi F, Hinman JD. PMID: 31978079; PMCID: PMC6980497.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Differential Item Functioning of the Everyday Cognition (ECog) Scales in Relation to Racial/Ethnic Groups. J Int Neuropsychol Soc. 2020 05; 26(5):515-526.
Filshtein T, Chan M, Mungas D, Whitmer R, Whitmer R, Fletcher E, DeCarli C, Farias S. PMID: 31973776.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease. Alzheimers Dement. 2020 04; 16(4):681-695.
Elahi FM, Casaletto KB, La Joie R, Walters SM, Harvey D, Wolf A, Edwards L, Rivera-Contreras W, Karydas A, Cobigo Y, Rosen HJ, DeCarli C, Miller BL, Rabinovici GD, Kramer JH. PMID: 31879236; PMCID: PMC7138729.
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PubMed Mentions:
97 Fields:
Translation:
HumansCells
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Circulating ceramide ratios and risk of vascular brain aging and dementia. Ann Clin Transl Neurol. 2020 02; 7(2):160-168.
McGrath ER, Himali JJ, Xanthakis V, Duncan MS, Schaffer JE, Ory DS, Peterson LR, DeCarli C, Pase MP, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. PMID: 31950603; PMCID: PMC7034495.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Association Between Leptin, Cognition, and Structural Brain Measures Among "Early" Middle-Aged Adults: Results from the Framingham Heart Study Third Generation Cohort. J Alzheimers Dis. 2020; 77(3):1279-1289.
Sanborn V, Preis SR, Ang A, Devine S, Mez J, DeCarli C, Au R, Alosco ML, Gunstad J. PMID: 32831199; PMCID: PMC7923949.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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The Impact of Amyloid-β or Tau on Cognitive Change in the Presence of Severe Cerebrovascular Disease. J Alzheimers Dis. 2020; 78(2):573-585.
Jang H, Kim HJ, Choe YS, Kim SJ, Park S, Kim Y, Kim KW, Lyoo CH, Cho H, Ryu YH, Choi JY, DeCarli C, Na DL, Seo SW, Alzheimer’s Disease Neuroimaging Initiative. PMID: 33016911.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease. Neurology. 2020 03 03; 94(9):e950-e960.
Soldan A, Pettigrew C, Zhu Y, Wang MC, Moghekar A, Gottesman RF, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M, BIOCARD Research Team. PMID: 31888969; PMCID: PMC7238945.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Association Between Central Blood Pressure and Subclinical Cerebrovascular Disease in Older Adults. Hypertension. 2020 02; 75(2):580-587.
Matsumoto K, Jin Z, Homma S, Elkind MSV, Rundek T, Mannina C, Lee TC, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 31865782; PMCID: PMC7008935.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals. Neurobiol Aging. 2020 04; 88:33-41.
Pettigrew C, Soldan A, Zhu Y, Cai Q, Wang MC, Moghekar A, Miller MI, Singh B, Martinez O, Fletcher E, DeCarli C, Albert M. PMID: 31932050; PMCID: PMC7160864.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Association of CD14 with incident dementia and markers of brain aging and injury. Neurology. 2020 01 21; 94(3):e254-e266.
Pase MP, Himali JJ, Beiser AS, DeCarli C, McGrath ER, Satizabal CL, Aparicio HJ, Adams HHH, Reiner AP, Longstreth WT, Fornage M, Tracy RP, Lopez O, Psaty BM, Levy D, Seshadri S, Bis JC. PMID: 31818907; PMCID: PMC7108812.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results. Alzheimers Dement. 2019 12; 15(12):1507-1515.
González HM, Tarraf W, Schneiderman N, Fornage M, Vásquez PM, Zeng D, Youngblood M, Gallo LC, Daviglus ML, Lipton RB, Kaplan R, Ramos AR, Lamar M, Thomas S, Chai A, DeCarli C. PMID: 31753701; PMCID: PMC7318558.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 11; 51(11):1624-1636.
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S, Arias-Vasquez A, Chauhan G, Athanasiu L, Rentería ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santiañez R, Kraemer B, Håberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Pütz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Sämann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdés Hernández MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR, Schofield PR, Mühleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jönsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaître H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Müller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Völzke H, Wright MJ, van 't Ent D, Nöthen MM, Ophoff RA, Buitelaar JK, Fernández G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA. PMID: 31636452; PMCID: PMC7055269.
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PubMed Mentions:
106 Fields:
Translation:
HumansAnimals
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Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways. Sci Rep. 2019 10 10; 9(1):14498.
Horgusluoglu-Moloch E, Risacher SL, Crane PK, Hibar D, Thompson PM, Saykin AJ, Nho K, Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 31601890; PMCID: PMC6787090.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders. Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):327-330.
Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, Bennett DA, Gearing M, Juncos JL, Kramer J, Lee SE, Yokoyama JS, Mendez MF, Chui H, Zarow C, Ringman JM, Kilic U, Babacan-Yildiz G, Levey A, DeCarli CS, Cotman CW, Boxer AL, Miller BL, Coppola G. PMID: 31513029; PMCID: PMC7050643.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Multimodal Hippocampal Subfield Grading For Alzheimer's Disease Classification. Sci Rep. 2019 09 25; 9(1):13845.
Hett K, Ta VT, Catheline G, Tourdias T, Manjón JV, Coupé P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31554909; PMCID: PMC6761169.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, et al. PMID: 31417202; PMCID: PMC7265117.
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25 Fields:
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Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients. Eur J Nucl Med Mol Imaging. 2020 02; 47(2):292-303.
Jang H, Kim HJ, Park S, Park YH, Choe Y, Cho H, Lyoo CH, Yoon U, Lee JS, Kim Y, Kim SJ, Kim JP, Jung YH, Ryu YH, Choi JY, Moon SH, Seong JK, DeCarli C, Weiner MW, Lockhart SN, Cho SH, Na DL, Seo SW. PMID: 31471715.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults. JAMA Netw Open. 2019 08 02; 2(8):e199826.
Zhu H, Tao Q, Ang TFA, Massaro J, Gan Q, Salim S, Zhu RY, Kolachalama VB, Zhang X, Devine S, Auerbach SH, DeCarli C, Au R, Qiu WQ. PMID: 31433485; PMCID: PMC6707010.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Commun Biol. 2019; 2:285.
van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C. PMID: 31396565; PMCID: PMC6677735.
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PubMed Mentions:
17 Translation:
Humans
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Circulating IGFBP-2: a novel biomarker for incident dementia. Ann Clin Transl Neurol. 2019 09; 6(9):1659-1670.
McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli CS, Pase MP, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. PMID: 31373442; PMCID: PMC6764739.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Plasma total-tau as a biomarker of stroke risk in the community. Ann Neurol. 2019 09; 86(3):463-467.
Pase MP, Himali JJ, Aparicio HJ, Romero JR, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S. PMID: 31271449; PMCID: PMC7297542.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Non-coding variability at the APOE locus contributes to the Alzheimer's risk. Nat Commun. 2019 07 25; 10(1):3310.
Zhou X, Chen Y, Mok KY, Kwok TCY, Mok VCT, Guo Q, Ip FC, Chen Y, Mullapudi N, Alzheimer’s Disease Neuroimaging Initiative, Giusti-Rodríguez P, Sullivan PF, Hardy J, Fu AKY, Li Y, Ip NY. PMID: 31346172; PMCID: PMC6658518.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Measures of obesity are associated with MRI markers of brain aging: The Northern Manhattan Study. Neurology. 2019 08 20; 93(8):e791-e803.
Caunca MR, Gardener H, Simonetto M, Cheung YK, Alperin N, Yoshita M, DeCarli C, Elkind MSV, Sacco RL, Wright CB, Rundek T. PMID: 31341005; PMCID: PMC6711659.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes. J Am Heart Assoc. 2019 07 16; 8(14):e012141.
Vasan RS, Short MI, Niiranen TJ, Xanthakis V, DeCarli C, Cheng S, Seshadri S, Mitchell GF. PMID: 31303106; PMCID: PMC6662123.
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PubMed Mentions:
45 Fields:
Translation:
Humans
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Relationship of Cancer to Brain Aging Markers of Alzheimer's Disease: The Framingham Heart Study. Adv Geriatr Med Res. 2019; 1.
Gupta A, Preis SR, Beiser AS, Splansky GL, DeCarli CS, Au R, Driver JA. PMID: 31355371; PMCID: PMC6659723.
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PubMed Mentions:
1
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Night-time systolic blood pressure and subclinical cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Eur Heart J Cardiovasc Imaging. 2019 Jul 01; 20(7):765-771.
Nakanishi K, Jin Z, Homma S, Elkind MSV, Rundek T, Schwartz JE, Lee TC, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 30649236; PMCID: PMC6587117.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study. J Am Geriatr Soc. 2019 09; 67(9):1827-1834.
Legdeur N, Visser PJ, Woodworth DC, Muller M, Fletcher E, Maillard P, Scheltens P, DeCarli C, Kawas CH, Corrada MM. PMID: 31169919; PMCID: PMC6732042.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. Acta Neuropathol. 2019 08; 138(2):237-250.
van der Lee SJ, Conway OJ, Jansen I, Carrasquillo MM, Kleineidam L, van den Akker E, Hernández I, van Eijk KR, Stringa N, Chen JA, Zettergren A, Andlauer TFM, Diez-Fairen M, Simon-Sanchez J, Lleó A, Zetterberg H, Nygaard M, Blauwendraat C, Savage JE, Mengel-From J, Moreno-Grau S, Wagner M, Fortea J, Keogh MJ, Blennow K, Skoog I, Friese MA, Pletnikova O, Zulaica M, Lage C, de Rojas I, Riedel-Heller S, Illán-Gala I, Wei W, Jeune B, Orellana A, Then Bergh F, Wang X, Hulsman M, Beker N, Tesi N, Morris CM, Indakoetxea B, Collij LE, Scherer M, Morenas-Rodríguez E, Ironside JW, van Berckel BNM, Alcolea D, Wiendl H, Strickland SL, Pastor P, Rodríguez Rodríguez E, DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Co, IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), Boeve BF, Petersen RC, Ferman TJ, van Gerpen JA, Reinders MJT, Uitti RJ, Tárraga L, Maier W, Dols-Icardo O, Kawalia A, Dalmasso MC, Boada M, Zettl UK, van Schoor NM, Beekman M, Allen M, Masliah E, de Munain AL, Pantelyat A, Wszolek ZK, Ross OA, Dickson DW, Graff-Radford NR, Knopman D, Rademakers R, Lemstra AW, Pijnenburg YAL, Scheltens P, Gasser T, Chinnery PF, Hemmer B, Huisman MA, Troncoso J, Moreno F, Nohr EA, Sørensen TIA, Heutink P, Sánchez-Juan P, Posthuma D, GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Clarimón J, Christensen K, Ertekin-Taner N, Scholz SW, Ramirez A, Ruiz A, Slagboom E, van der Flier WM, Holstege H. PMID: 31131421; PMCID: PMC6660501.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Interpretable classification of Alzheimer's disease pathologies with a convolutional neural network pipeline. Nat Commun. 2019 05 15; 10(1):2173.
Tang Z, Chuang KV, DeCarli C, Jin LW, Beckett L, Keiser MJ, Dugger BN. PMID: 31092819; PMCID: PMC6520374.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes. JAMA Neurol. 2019 05 01; 76(5):598-606.
Pase MP, Beiser AS, Himali JJ, Satizabal CL, Aparicio HJ, DeCarli C, Chêne G, Dufouil C, Seshadri S. PMID: 30830207; PMCID: PMC6515589.
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PubMed Mentions:
82 Fields:
Translation:
Humans
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Cardiovascular disease risk factor burden and cognition: Implications of ethnic diversity within the Hispanic Community Health Study/Study of Latinos. PLoS One. 2019; 14(4):e0215378.
Lamar M, Durazo-Arvizu RA, Sachdeva S, Pirzada A, Perreira KM, Rundek T, Gallo LC, Grober E, DeCarli C, Lipton RB, Tarraf W, González HM, Daviglus ML. PMID: 31009492; PMCID: PMC6476505.
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PubMed Mentions:
15 Fields:
Translation:
HumansPHPublic Health
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The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. Nat Commun. 2019 04 16; 10(1):1766.
Franzmeier N, Rubinski A, Neitzel J, Ewers M, Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 30992433; PMCID: PMC6467911.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Cerebral white matter free water: A sensitive biomarker of cognition and function. Neurology. 2019 05 07; 92(19):e2221-e2231.
Maillard P, Fletcher E, Singh B, Martinez O, Johnson DK, Olichney JM, Farias ST, DeCarli C. PMID: 30952798; PMCID: PMC6537135.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. JAMA Netw Open. 2019 04 05; 2(4):e192745.
Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S. PMID: 31002329; PMCID: PMC6481600.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings. Alzheimers Dement (Amst). 2019 Dec; 11:286-290.
Adams HHH, Roshchupkin GV, DeCarli C, Franke B, Grabe HJ, Habes M, Jahanshad N, Medland SE, Niessen W, Satizabal CL, Schmidt R, Seshadri S, Teumer A, Thompson PM, Vernooij MW, Wittfeld K, Ikram MA. PMID: 30976649; PMCID: PMC6441785.
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PubMed Mentions:
2
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Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia. Neurology. 2019 03 26; 92(13):631-634.
Bissig D, DeCarli CS. PMID: 30910941; PMCID: PMC6453772.
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PubMed Mentions:
2 Fields:
Translation:
HumansPHPublic Health
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A blood-based signature of cerebrospinal fluid Aβ1-42 status. Sci Rep. 2019 03 11; 9(1):4163.
Goudey B, Fung BJ, Schieber C, Faux NG, Alzheimer’s Disease Metabolomics Consortium, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30853713; PMCID: PMC6409361.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, et al. PMID: 30820047; PMCID: PMC6463297.
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PubMed Mentions:
1175 Fields:
Translation:
Humans
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Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimers Dement (Amst). 2019 Dec; 11:191-204.
Smith EE, Biessels GJ, De Guio F, de Leeuw FE, Duchesne S, Düring M, Frayne R, Ikram MA, Jouvent E, MacIntosh BJ, Thrippleton MJ, Vernooij MW, Adams H, Backes WH, Ballerini L, Black SE, Chen C, Corriveau R, DeCarli C, Greenberg SM, Gurol ME, Ingrisch M, Job D, Lam BYK, Launer LJ, Linn J, McCreary CR, Mok VCT, Pantoni L, Pike GB, Ramirez J, Reijmer YD, Romero JR, Ropele S, Rost NS, Sachdev PS, Scott CJM, Seshadri S, Sharma M, Sourbron S, Steketee RME, Swartz RH, van Oostenbrugge R, van Osch M, van Rooden S, Viswanathan A, Werring D, Dichgans M, Wardlaw JM. PMID: 30859119; PMCID: PMC6396326.
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PubMed Mentions:
38
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Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics. Sci Rep. 2019 02 19; 9(1):2235.
Varatharajah Y, Ramanan VK, Iyer R, Vemuri P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30783207; PMCID: PMC6381141.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Predicting Alzheimer's disease progression using multi-modal deep learning approach. Sci Rep. 2019 02 13; 9(1):1952.
Lee G, Nho K, Kang B, Sohn KA, Kim D, for Alzheimer’s Disease Neuroimaging Initiative. PMID: 30760848; PMCID: PMC6374429.
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PubMed Mentions:
92 Fields:
Translation:
Humans
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Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis. Neurology. 2019 03 05; 92(10):e1086-e1097.
Yakushiji Y, Wilson D, Ambler G, Charidimou A, Beiser A, van Buchem MA, DeCarli C, Ding D, Gudnason V, Hara H, Imaizumi T, Kohara K, Kwon HM, Launer LJ, Mok V, Phan T, Preis SR, Romero JR, Seshadri S, Srikanth V, Takashima Y, Tsushima Y, Wang Z, Wolf PA, Xiong Y, Yamaguchi S, Werring DJ. PMID: 30709966; PMCID: PMC6442016.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Extravascular fibrinogen in the white matter of Alzheimer's disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer's disease. Brain Pathol. 2019 05; 29(3):414-424.
McAleese KE, Graham S, Dey M, Walker L, Erskine D, Johnson M, Johnston E, Thomas AJ, McKeith IG, DeCarli C, Attems J. PMID: 30485582; PMCID: PMC8028661.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. 2019 Jan 28; 92(5):e486-e503.
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT, Debette S, Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alz. PMID: 30651383; PMCID: PMC6369905.
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PubMed Mentions:
16 Fields:
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Type 2 diabetes mellitus, brain atrophy, and cognitive decline. Neurology. 2019 02 19; 92(8):e823-e830.
Moran C, Beare R, Wang W, Callisaya M, Srikanth V, Alzheimer's Disease Neuroimaging Initiative (ADNI). PMID: 30674592; PMCID: PMC7987953.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts. J Alzheimers Dis. 2019; 68(1):357-365.
Conner SC, Benayoun L, Himali JJ, Adams SL, Yang Q, DeCarli C, Blusztajn JK, Beiser A, Seshadri S, Delalle I. PMID: 30775993; PMCID: PMC6481535.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury. J Alzheimers Dis. 2019; 68(1):187-196.
DeCarli C, Villeneuve S, Maillard P, Harvey D, Singh B, Carmichael O, Fletcher E, Olichney J, Farias S, Jagust W, Reed B, Mungas D. PMID: 30775991; PMCID: PMC6615551.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer's Disease Center. J Alzheimers Dis. 2019; 68(1):145-158.
Filshtein TJ, Dugger BN, Jin LW, Olichney JM, Farias ST, Carvajal-Carmona L, Lott P, Mungas D, Reed B, Beckett LA, DeCarli C. PMID: 30775996; PMCID: PMC7286069.
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PubMed Mentions:
45 Fields:
Translation:
Humans
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Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members. Alzheimer Dis Assoc Disord. 2019 Jan-Mar; 33(1):1-6.
Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas D, DeCarli CS, Whitmer RA, Whitmer RA. PMID: 30106754; PMCID: PMC6374212.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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"Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders. Front Aging Neurosci. 2018; 10:343.
Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH. PMID: 30483114; PMCID: PMC6244607.
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PubMed Mentions:
16
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Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia. Mol Neurobiol. 2019 Jul; 56(7):4916-4924.
Schilling LP, Pascoal TA, Zimmer ER, Mathotaarachchi S, Shin M, de Mello Rieder CR, Gauthier S, Palmini A, Rosa-Neto P, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30414086.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study. Neurology. 2018 11 20; 91(21):e1961-e1970.
Echouffo-Tcheugui JB, Conner SC, Himali JJ, Maillard P, DeCarli CS, Beiser AS, Vasan RS, Seshadri S. PMID: 30355700; PMCID: PMC6260201.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants. Neuroimage Clin. 2019; 21:101581.
Khlif MS, Egorova N, Werden E, Redolfi A, Boccardi M, DeCarli CS, Fletcher E, Singh B, Li Q, Bird L, Brodtmann A. PMID: 30606656; PMCID: PMC6411582.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology. Alzheimers Dement. 2019 02; 15(2):205-216.
La Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Doré V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD. PMID: 30347188; PMCID: PMC6368897.
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PubMed Mentions:
109 Fields:
Translation:
Humans
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Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference. Nat Commun. 2018 10 15; 9(1):4273.
Young AL, Marinescu RV, Oxtoby NP, Bocchetta M, Yong K, Firth NC, Cash DM, Thomas DL, Dick KM, Cardoso J, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R, Finger E, de Mendonça A, Sorbi S, Warren JD, Crutch S, Fox NC, Ourselin S, Schott JM, Rohrer JD, Alexander DC, Genetic FTD Initiative (GENFI), Alzheimer’s Disease Neuroimaging Initiative (ADNI). PMID: 30323170; PMCID: PMC6189176.
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PubMed Mentions:
163 Fields:
Translation:
Humans
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Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study. PLoS One. 2018; 13(10):e0203774.
Hunter MD, Park Moon Y, DeCarli C, Gutierrez J, Wright CB, Di Tullio MR, Sacco RL, Kamel H, Elkind MSV. PMID: 30312297; PMCID: PMC6193576.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers. JAMA Netw Open. 2018 10 05; 1(6):e183597.
Tao Q, Ang TFA, DeCarli C, Auerbach SH, Devine S, Stein TD, Zhang X, Massaro J, Au R, Qiu WQ. PMID: 30646251; PMCID: PMC6324596.
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PubMed Mentions:
101 Fields:
Translation:
Humans
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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 09 26; 9(1):3945.
Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. PMID: 30258056; PMCID: PMC6158214.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Vascular risk at younger ages most strongly associates with current and future brain volume. Neurology. 2018 10 16; 91(16):e1479-e1486.
Pase MP, Davis-Plourde K, Himali JJ, Satizabal CL, Aparicio H, Seshadri S, Beiser AS, DeCarli C. PMID: 30232248; PMCID: PMC6202941.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer's disease. Sci Rep. 2018 09 14; 8(1):13807.
Huang SY, Hsu JL, Lin KJ, Liu HL, Wey SP, Hsiao IT, Alzheimer’s Disease Neuroimaging Initiative. PMID: 30218083; PMCID: PMC6138637.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. Stroke. 2018 09; 49(9):2227-2229.
Raman MR, Himali JJ, Conner SC, DeCarli C, Vasan RS, Beiser AS, Seshadri S, Maillard P, Satizabal CL. PMID: 30354979; PMCID: PMC6101979.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition. Neurobiol Aging. 2018 12; 72:14-22.
Seiler S, Fletcher E, Hassan-Ali K, Weinstein M, Beiser A, Himali JJ, Satizabal CL, Seshadri S, DeCarli C, Maillard P. PMID: 30172922; PMCID: PMC6242702.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke. 2018 08; 49(8):1812-1819.
Jian X, Satizabal CL, Smith AV, Wittfeld K, Bis JC, Smith JA, Hsu FC, Nho K, Hofer E, Hagenaars SP, Nyquist PA, Mishra A, Adams HHH, Li S, Teumer A, Zhao W, Freedman BI, Saba Y, Yanek LR, Chauhan G, van Buchem MA, Cushman M, Royle NA, Bryan RN, Niessen WJ, Windham BG, DeStefano AL, Habes M, Heckbert SR, Palmer ND, Lewis CE, Eiriksdottir G, Maillard P, Mathias RA, Homuth G, Valdés-Hernández MDC, Divers J, Beiser AS, Langner S, Rice KM, Bastin ME, Yang Q, Maldjian JA, Starr JM, Sidney S, Risacher SL, Uitterlinden AG, Gudnason VG, Nauck M, Rotter JI, Schreiner PJ, Boerwinkle E, van Duijn CM, Mazoyer B, von Sarnowski B, Gottesman RF, Levy D, Sigurdsson S, Vernooij MW, Turner ST, Schmidt R, Wardlaw JM, Psaty BM, Mosley TH, DeCarli CS, Saykin AJ, Bowden DW, Becker DM, Deary IJ, Schmidt H, Kardia SLR, Ikram MA, Debette S, Grabe HJ, Longstreth WT, Seshadri S, Launer LJ, Fornage M, neuroCHARGE Working Group. PMID: 30002152; PMCID: PMC6202149.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging. JAMA Neurol. 2018 08 01; 75(8):999-1007.
Kim HJ, Park S, Cho H, Jang YK, San Lee J, Jang H, Kim Y, Kim KW, Ryu YH, Choi JY, Moon SH, Weiner MW, Jagust WJ, Rabinovici GD, DeCarli C, Lyoo CH, Na DL, Seo SW. PMID: 29799981; PMCID: PMC6142932.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. JAMA Neurol. 2018 08 01; 75(8):989-998.
Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL, Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative. PMID: 29801024; PMCID: PMC6142927.
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PubMed Mentions:
136 Fields:
Translation:
HumansCells
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Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. PMID: 29967939; PMCID: PMC6280657.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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Cortical tau pathology: a major player in fibre-specific white matter reductions in Alzheimer's disease? Brain. 2018 06 01; 141(6):e44.
McAleese KE, Walker L, Colloby SJ, Taylor JP, Thomas AJ, DeCarli C, Attems J. PMID: 29668888.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Greater depressive symptoms, cognition, and markers of brain aging: Northern Manhattan Study. Neurology. 2018 06 05; 90(23):e2077-e2085.
Zeki Al Hazzouri A, Caunca MR, Nobrega JC, Elfassy T, Cheung YK, Alperin N, Dong C, Elkind MSV, Sacco RL, DeCarli C, Wright CB. PMID: 29743209; PMCID: PMC5993180.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses. Alzheimers Dement (Amst). 2018; 10:382-393.
Fletcher E, Filshtein TJ, Harvey D, Renaud A, Mungas D, DeCarli C. PMID: 29984299; PMCID: PMC6031152.
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PubMed Mentions:
11
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve. Neurobiol Aging. 2018 08; 68:142-150.
Mungas D, Gavett B, Fletcher E, Farias ST, DeCarli C, Reed B. PMID: 29798764; PMCID: PMC5993638.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images. Sci Rep. 2018 04 09; 8(1):5697.
Lu D, Popuri K, Ding GW, Balachandar R, Beg MF, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29632364; PMCID: PMC5890270.
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PubMed Mentions:
96 Fields:
Translation:
Humans
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Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states. Sci Rep. 2018 03 07; 8(1):4103.
Mahjoub I, Mahjoub MA, Rekik I, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29515158; PMCID: PMC5841319.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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PubMed Mentions:
59 Fields:
Translation:
Humans
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A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis. 2018; 63(4):1347-1360.
Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. PMID: 29843242; PMCID: PMC6081639.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-aged Adults in the Framingham Study. JAMA Neurol. 2018 01 01; 75(1):97-104.
Weinstein G, Zelber-Sagi S, Preis SR, Beiser AS, DeCarli C, Speliotes EK, Satizabal CL, Vasan RS, Seshadri S. PMID: 29159396; PMCID: PMC5833484.
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PubMed Mentions:
71 Fields:
Translation:
Humans
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Baseline White Matter Hyperintensities and Hippocampal Volume are Associated With Conversion From Normal Cognition to Mild Cognitive Impairment in the Framingham Offspring Study. Alzheimer Dis Assoc Disord. 2018 Jan-Mar; 32(1):50-56.
Bangen KJ, Preis SR, Delano-Wood L, Wolf PA, Libon DJ, Bondi MW, Au R, DeCarli C, Brickman AM. PMID: 28984639; PMCID: PMC5821543.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly. Stroke. 2018 02; 49(2):319-324.
Nakanishi K, Jin Z, Homma S, Elkind MSV, Rundek T, Lee SC, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 29284731; PMCID: PMC5870891.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. 2018 01 16; 90(3):e188-e196.
Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Neurocognitive Working Group. PMID: 29282330; PMCID: PMC5772158.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Stroke: 'Brain health': what is it, what can we do about it and when should we start? Nat Rev Neurol. 2018 Jan; 14(1):6-8.
DeCarli C. PMID: 29192257.
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Humans
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Validation of T1w-based segmentations of white matter hyperintensity volumes in large-scale datasets of aging. Hum Brain Mapp. 2018 03; 39(3):1093-1107.
Dadar M, Maranzano J, Ducharme S, Carmichael OT, Decarli C, Collins DL, Alzheimer's Disease Neuroimaging Initiative. PMID: 29181872; PMCID: PMC6866430.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Blood pressure from mid- to late life and risk of incident dementia. Neurology. 2017 Dec 12; 89(24):2447-2454.
McGrath ER, Beiser AS, DeCarli C, Plourde KL, Vasan RS, Greenberg SM, Seshadri S. PMID: 29117954; PMCID: PMC5729797.
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PubMed Mentions:
97 Fields:
Translation:
Humans
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Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty. Sci Rep. 2017 10 25; 7(1):14052.
Du L, Liu K, Yao X, Yan J, Risacher SL, Han J, Guo L, Saykin AJ, Shen L, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29070790; PMCID: PMC5656688.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement. 2018 03; 14(3):280-292.
Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG. PMID: 29055812.
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PubMed Mentions:
144 Fields:
Translation:
Humans
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Female sex, early-onset hypertension, and risk of dementia. Neurology. 2017 Oct 31; 89(18):1886-1893.
Gilsanz P, Mayeda ER, Glymour MM, Quesenberry CP, Mungas DM, DeCarli C, Dean A, Whitmer RA, Whitmer RA. PMID: 28978656; PMCID: PMC5664296.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Author response: Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology. 2017 10 03; 89(14):1533.
Pase MP, Westwood AJ, Beiser A, Jain N, DeCarli C, Himali JJ, Auerbach SH, Seshadri S. PMID: 28972111.
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Humans
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Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Neurol Genet. 2017 Oct; 3(5):e185.
Beecham A, Dong C, Wright CB, Dueker N, Brickman AM, Wang L, DeCarli C, Blanton SH, Rundek T, Mayeux R, Sacco RL. PMID: 28975155; PMCID: PMC5619914.
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PubMed Mentions:
5
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Subclinical Cerebrovascular Disease Increases the Risk of Incident Stroke and Mortality: The Northern Manhattan Study. J Am Heart Assoc. 2017 Aug 28; 6(9).
Wright CB, Dong C, Perez EJ, De Rosa J, Yoshita M, Rundek T, DeCarli C, Gutierrez J, Elkind MSV, Sacco RL. PMID: 28847914; PMCID: PMC5634244.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults. J Am Heart Assoc. 2017 Aug 17; 6(8).
Cooper LL, Himali JJ, Torjesen A, Tsao CW, Beiser A, Hamburg NM, DeCarli C, Vasan RS, Seshadri S, Pase MP, Mitchell GF. PMID: 28862943; PMCID: PMC5586458.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features. Sci Rep. 2017 08 15; 7(1):8137.
Singanamalli A, Wang H, Madabhushi A, Alzheimer’s Disease Neuroimaging Initiative. PMID: 28811553; PMCID: PMC5558022.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Low-frequency oscillations in default mode subnetworks are associated with episodic memory impairments in Alzheimer's disease. Neurobiol Aging. 2017 11; 59:98-106.
Veldsman M, Egorova N, Singh B, Mungas D, DeCarli C, Brodtmann A. PMID: 28866021.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, et al. PMID: 28714976; PMCID: PMC5669039.
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PubMed Mentions:
456 Fields:
Translation:
HumansCells
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Performance comparison of 10 different classification techniques in segmenting white matter hyperintensities in aging. Neuroimage. 2017 08 15; 157:233-249.
Dadar M, Maranzano J, Misquitta K, Anor CJ, Fonov VS, Tartaglia MC, Carmichael OT, Decarli C, Collins DL, Alzheimer's Disease Neuroimaging Initiative. PMID: 28602597; PMCID: PMC6469398.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study. Atherosclerosis. 2017 10; 265:305-311.
Aparicio HJ, Petrea RE, Massaro JM, Manning WJ, Oyama-Manabe N, Beiser AS, Kase CS, D'Agostino RB, Wolf PA, Vasan RS, DeCarli C, O'Donnell CJ, Seshadri S. PMID: 28673480; PMCID: PMC5617776.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease. Acta Neuropathol. 2017 Sep; 134(3):459-473.
McAleese KE, Walker L, Graham S, Moya ELJ, Johnson M, Erskine D, Colloby SJ, Dey M, Martin-Ruiz C, Taylor JP, Thomas AJ, McKeith IG, De Carli C, Attems J. PMID: 28638989; PMCID: PMC5563333.
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PubMed Mentions:
109 Fields:
Translation:
Humans
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Triglycerides are negatively correlated with cognitive function in nondemented aging adults. Neuropsychology. 2017 Sep; 31(6):682-688.
Parthasarathy V, Frazier DT, Bettcher BM, Jastrzab L, Chao L, Chao L, Reed B, Mungas D, Weiner M, DeCarli C, Chui H, Kramer JH. PMID: 28604016; PMCID: PMC5726405.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Effects of traumatic brain injury and posttraumatic stress disorder on development of Alzheimer's disease in Vietnam Veterans using the Alzheimer's Disease Neuroimaging Initiative: Preliminary Report. Alzheimers Dement (N Y). 2017 06; 3(2):177-188.
Weiner MW, Harvey D, Hayes J, Landau SM, Aisen PS, Petersen RC, Tosun D, Veitch DP, Jack CR, Decarli C, Saykin AJ, Grafman J, Neylan TC, Department of Defense Alzheimer's Disease Neuroimaging Initiative. PMID: 28758146; PMCID: PMC5526098.
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PubMed Mentions:
36
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Physical Activity, Brain Volume, and Dementia Risk: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):789-795.
Tan ZS, Spartano NL, Beiser AS, DeCarli C, Auerbach SH, Vasan RS, Seshadri S. PMID: 27422439; PMCID: PMC6075525.
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PubMed Mentions:
83 Fields:
Translation:
Humans
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Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions. Front Aging Neurosci. 2017; 9:132.
Kern KC, Wright CB, Bergfield KL, Fitzhugh MC, Chen K, Moeller JR, Nabizadeh N, Elkind MSV, Sacco RL, Stern Y, DeCarli CS, Alexander GE. PMID: 28555103; PMCID: PMC5430031.
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PubMed Mentions:
19
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Impact of multiple pathologies on the threshold for clinically overt dementia. Acta Neuropathol. 2017 08; 134(2):171-186.
Kapasi A, DeCarli C, Schneider JA. PMID: 28488154; PMCID: PMC5663642.
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PubMed Mentions:
267 Fields:
Translation:
Humans
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Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. Stroke. 2017 06; 48(6):1567-1573.
Maillard P, Mitchell GF, Himali JJ, Beiser A, Fletcher E, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. PMID: 28473633; PMCID: PMC5502744.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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Relationship between carotid arterial properties and cerebral white matter hyperintensities. Neurology. 2017 May 23; 88(21):2036-2042.
Rundek T, Della-Morte D, Gardener H, Dong C, Markert MS, Gutierrez J, Roberts E, Elkind MSV, DeCarli C, Sacco RL, Wright CB. PMID: 28446647; PMCID: PMC5440241.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Age-related white matter integrity differences in oldest-old without dementia. Neurobiol Aging. 2017 08; 56:108-114.
Bennett IJ, Greenia DE, Maillard P, Sajjadi SA, DeCarli C, Corrada MM, Kawas CH. PMID: 28527525; PMCID: PMC5647141.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Validation of a Regression Technique for Segmentation of White Matter Hyperintensities in Alzheimer's Disease. IEEE Trans Med Imaging. 2017 08; 36(8):1758-1768.
Dadar M, Pascoal TA, Manitsirikul S, Misquitta K, Fonov VS, Tartaglia MC, Breitner J, Rosa-Neto P, Carmichael OT, Decarli C, Collins DL. PMID: 28422655.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement. 2017 Sep; 13(9):955-964.
Pase MP, Himali JJ, Jacques PF, DeCarli C, Satizabal CL, Aparicio H, Vasan RS, Beiser AS, Seshadri S. PMID: 28274718; PMCID: PMC6820519.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study. Neurobiol Aging. 2017 06; 54:94-99.
Romero JR, Beiser A, Himali JJ, Shoamanesh A, DeCarli C, Seshadri S. PMID: 28347929; PMCID: PMC5401784.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Medicare Expenditure Correlates of Atrophy and Cerebrovascular Disease in Older Adults. Exp Aging Res. 2017 Mar-Apr; 43(2):149-160.
Last BS, García Rubio MJ, Zhu CW, Cosentino S, Manly JJ, DeCarli C, Stern Y, Brickman AM. PMID: 28230421; PMCID: PMC5635423.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Strategies for enhancing research in aging health disparities by mentoring diverse investigators. J Clin Transl Sci. 2017 Jun; 1(3):167-175.
Harawa NT, Manson SM, Mangione CM, Penner LA, Norris KC, DeCarli C, Scarinci IC, Zissimopoulos J, Buchwald DS, Hinton L, Pérez-Stable EJ. PMID: 28856013; PMCID: PMC5573262.
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PubMed Mentions:
16
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Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Neurology. 2017 Mar 21; 88(12):1172-1179.
Westwood AJ, Beiser A, Jain N, Himali JJ, DeCarli C, Auerbach SH, Pase MP, Seshadri S. PMID: 28228567; PMCID: PMC5373785.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Alzheimer's Disease Genetics Consortium, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. PMID: 28183528; PMCID: PMC5496797.
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PubMed Mentions:
107 Fields:
Translation:
Humans
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Neighborhood Socioeconomic Status and Cognitive Trajectories in a Diverse Longitudinal Cohort. Clin Gerontol. 2018 Jan-Feb; 41(1):82-93.
Meyer OL, Mungas D, King J, Hinton L, Farias S, Reed B, DeCarli C, Geraghty E, Beckett L. PMID: 28452649; PMCID: PMC5522784.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study. Stroke. 2017 03; 48(3):781-783.
Romero JR, Preis SR, Beiser A, Himali JJ, Shoamanesh A, Wolf PA, Kase CS, Vasan RS, DeCarli C, Seshadri S. PMID: 28143923; PMCID: PMC5330856.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage: The Northern Manhattan Study. Stroke. 2017 03; 48(3):604-610.
Katan M, Moon Y, von Eckardstein A, Spanaus K, DeRosa J, Gutierrez J, DeCarli C, Wright C, Sacco R, Elkind M. PMID: 28123058; PMCID: PMC5330783.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Independent value added by diffusion MRI for prediction of cognitive function in older adults. Neuroimage Clin. 2017; 14:166-173.
Scott JA, Tosun D, Braskie MN, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT, ADNI. PMID: 28180075; PMCID: PMC5279696.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 01 18; 8:13624.
Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CRK, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jørgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DCM, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Muñoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LMO, Oosterlaan J, Papmeyer M, Pirpamer L, Pütz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Sämann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MMJ, Van Eijk KR, Van Erp TGM, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJM, De Geus EJC, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HHH, Green RC, Gruber O, Gudnason V, Guelfi S, Håberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Hulshoff Pol HE, Ikeda M, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hernández MCV, Van der Brug M, van der Lugt A, van der Wee NJA, Van Haren NEM, et al. PMID: 28098162; PMCID: PMC5253632.
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PubMed Mentions:
143 Fields:
Translation:
Humans
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Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease. Sci Rep. 2017 01 12; 7:39880.
Huang M, Yang W, Feng Q, Chen W, Alzheimer’s Disease Neuroimaging Initiative. PMID: 28079104; PMCID: PMC5227696.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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MRI Markers Predict Cognitive Decline Assessed by Telephone Interview: The Northern Manhattan Study. Alzheimer Dis Assoc Disord. 2017 Jan-Mar; 31(1):34-40.
Wright CB, Dong C, Caunca MR, DeRosa J, Kuen Cheng Y, Rundek T, Elkind MS, DeCarli C, Sacco RL. PMID: 27467026; PMCID: PMC5272913.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study). Stroke. 2017 02; 48(2):486-489.
Lioutas VA, Beiser A, Himali J, Aparicio H, Romero JR, DeCarli C, Seshadri S. PMID: 28008091; PMCID: PMC5288009.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Left ventricular mass-geometry and silent cerebrovascular disease: The Cardiovascular Abnormalities and Brain Lesions (CABL) study. Am Heart J. 2017 Mar; 185:85-92.
Nakanishi K, Jin Z, Homma S, Elkind MS, Rundek T, Tugcu A, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 28267479; PMCID: PMC5341701.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The Vascular Impairment of Cognition Classification Consensus Study. Alzheimers Dement. 2017 Jun; 13(6):624-633.
Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I, VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG. PMID: 27960092.
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PubMed Mentions:
81 Fields:
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Relation of Dysglycemia to Structural Brain Changes in a Multiethnic Elderly Cohort. J Am Geriatr Soc. 2017 Feb; 65(2):277-285.
Reitz C, Guzman VA, Narkhede A, DeCarli C, Brickman AM, Luchsinger JA. PMID: 27917464; PMCID: PMC5311018.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort. Neuroimage Clin. 2017; 13:130-137.
Seo SW, Ayakta N, Grinberg LT, Villeneuve S, Lehmann M, Reed B, DeCarli C, Miller BL, Rosen HJ, Boxer AL, O'Neil JP, Jin LW, Seeley WW, Jagust WJ, Rabinovici GD. PMID: 27981028; PMCID: PMC5144753.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016 Nov 29; 87(22):2324-2332.
Zhan X, Stamova B, Jin LW, DeCarli C, Phinney B, Sharp FR. PMID: 27784770; PMCID: PMC5135029.
View in:
PubMed Mentions:
212 Fields:
Translation:
HumansCells
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Atherosclerotic Plaques in the Aortic Arch and Subclinical Cerebrovascular Disease. Stroke. 2016 11; 47(11):2813-2819.
Tugcu A, Jin Z, Homma S, Elkind MS, Rundek T, Yoshita M, DeCarli C, Nakanishi K, Shames S, Wright CB, Sacco RL, Di Tullio MR. PMID: 27729581; PMCID: PMC5134895.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 12; 19(12):1569-1582.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, et al. PMID: 27694991; PMCID: PMC5227112.
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PubMed Mentions:
118 Fields:
Translation:
Humans
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Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis. JAMA Neurol. 2016 Oct 01; 73(10):1208-1216.
Yassine HN, Feng Q, Azizkhanian I, Rawat V, Castor K, Fonteh AN, Harrington MG, Zheng L, Reed BR, DeCarli C, Jagust WJ, Chui HC. PMID: 27532692.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Progression from normal cognition to mild cognitive impairment in a diverse clinic-based and community-based elderly cohort. Alzheimers Dement. 2017 Apr; 13(4):399-405.
Chen Y, Denny KG, Harvey D, Farias ST, Mungas D, DeCarli C, Beckett L. PMID: 27590706; PMCID: PMC5451154.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults. Neurobiol Aging. 2016 12; 48:48-52.
Scott JA, Braskie MN, Tosun D, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT, ADNI. PMID: 27639120; PMCID: PMC5798609.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. Alzheimers Dement. 2016 12; 12(12):1235-1249.
METACOHORTS Consortium. Electronic address: joanna.wardlaw@ed.ac.uk, METACOHORTS Consortium. PMID: 27490018; PMCID: PMC5399602.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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Association of Physical Function with Clinical and Subclinical Brain Disease: The Framingham Offspring Study. J Alzheimers Dis. 2016 07 14; 53(4):1597-608.
Camargo EC, Weinstein G, Beiser AS, Tan ZS, DeCarli C, Kelly-Hayes M, Kase C, Murabito JM, Seshadri S. PMID: 27540965.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Association between atrial fibrillation and volumetric magnetic resonance imaging brain measures: Framingham Offspring Study. Heart Rhythm. 2016 10; 13(10):2020-4.
Piers RJ, Nishtala A, Preis SR, DeCarli C, Wolf PA, Benjamin EJ, Au R. PMID: 27417740; PMCID: PMC5035234.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis. Nat Commun. 2016 06 21; 7:11934.
Iturria-Medina Y, Sotero RC, Toussaint PJ, Mateos-Pérez JM, Evans AC, Alzheimer’s Disease Neuroimaging Initiative. PMID: 27327500; PMCID: PMC4919512.
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PubMed Mentions:
490 Fields:
Translation:
Humans
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Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia. Stroke. 2016 05; 47(5):1201-6.
Pase MP, Beiser A, Enserro D, Xanthakis V, Aparicio H, Satizabal CL, Himali JJ, Kase CS, Vasan RS, DeCarli C, Seshadri S. PMID: 27073239; PMCID: PMC5006676.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Effects of white matter integrity and brain volumes on late life depression in the Framingham Heart Study. Int J Geriatr Psychiatry. 2017 02; 32(2):214-221.
Qiu WQ, Himali JJ, Wolf PA, DeCarli DC, Beiser A, Au R. PMID: 27059548; PMCID: PMC5052093.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Neck Circumference, Brain Imaging Measures, and Neuropsychological Testing Measures. J Stroke Cerebrovasc Dis. 2016 Jul; 25(7):1570-1581.
Therkelsen KE, Preis SR, Beiser A, DeCarli C, Seshadri S, Wolf P, Au R, Fox CS. PMID: 27056441.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study. J Am Heart Assoc. 2016 Mar 18; 5(3):e002377.
Romero JR, Preis SR, Beiser A, DeCarli C, D'Agostino RB, Wolf PA, Vasan RS, Polak JF, Seshadri S. PMID: 26994127; PMCID: PMC4943235.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study. Stroke. 2016 Apr; 47(4):1030-6.
Maillard P, Mitchell GF, Himali JJ, Beiser A, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C. PMID: 26965846; PMCID: PMC4811686.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Fibroblast Growth Factor 23 Is Associated With Subclinical Cerebrovascular Damage: The Northern Manhattan Study. Stroke. 2016 Apr; 47(4):923-8.
Wright CB, Shah NH, Mendez AJ, DeRosa JT, Yoshita M, Elkind MS, Sacco RL, DeCarli C, Rundek T, Silverberg S, Dong C, Wolf M. PMID: 26956260; PMCID: PMC4811730.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging. 2016 May; 41:200.e13-200.e20.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK, Alzheimer's Disease Genetics Consortium (ADGC). PMID: 27036079; PMCID: PMC4948179.
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PubMed Mentions:
115 Fields:
Translation:
Humans
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25-Hydroxyvitamin D in Patients With Cognitive Decline-Reply. JAMA Neurol. 2016 Mar; 73(3):358.
Miller JW, Green R, DeCarli C. PMID: 26751272; PMCID: PMC5024784.
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PubMed Mentions: Fields:
Translation:
Humans
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Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One. 2016; 11(2):e0148717.
Karch CM, Ezerskiy LA, Bertelsen S, Alzheimer’s Disease Genetics Consortium (ADGC), Goate AM. PMID: 26919393; PMCID: PMC4769299.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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β-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individuals. Neurobiol Aging. 2016 Apr; 40:173-180.
Fletcher E, Villeneuve S, Maillard P, Harvey D, Reed B, Jagust W, DeCarli C. PMID: 26973117; PMCID: PMC4792128.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later. Neurology. 2016 Apr 05; 86(14):1313-1319.
Spartano NL, Himali JJ, Beiser AS, Lewis GD, DeCarli C, Vasan RS, Seshadri S. PMID: 26865519; PMCID: PMC4826343.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology. 2016 Feb 16; 86(7):619-26.
Tsao CW, Himali JJ, Beiser AS, Larson MG, DeCarli C, Vasan RS, Mitchell GF, Seshadri S. PMID: 26791155; PMCID: PMC4762417.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
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Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension. 2016 Mar; 67(3):513-9.
Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S. PMID: 26754644; PMCID: PMC4752398.
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PubMed Mentions:
77 Fields:
Translation:
Humans
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Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study. J Alzheimers Dis. 2016; 51(2):451-61.
Karakis I, Pase MP, Beiser A, Booth SL, Jacques PF, Rogers G, DeCarli C, Vasan RS, Wang TJ, Himali JJ, Annweiler C, Seshadri S. PMID: 26890771; PMCID: PMC4911705.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study. Stroke. 2016 Feb; 47(2):383-9.
Nayor M, Enserro DM, Beiser AS, Cheng S, DeCarli C, Vasan RS, Seshadri S. PMID: 26696648; PMCID: PMC4729607.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. Front Aging Neurosci. 2015; 7:221.
Scott JA, Braskie MN, Tosun D, Thompson PM, Weiner M, DeCarli C, Carmichael OT, Alzheimer’s Disease Neuroimaging Initiative. PMID: 26648866; PMCID: PMC4664630.
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PubMed Mentions:
35
-
Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury. Alzheimers Dement. 2016 Apr; 12(4):438-45.
Pase MP, Beiser A, Aparicio H, DeCarli C, Vasan RS, Murabito J, Seshadri S. PMID: 26542262; PMCID: PMC4841714.
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PubMed Mentions:
9 Fields:
Translation:
Humans
-
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23.
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith PA, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, St George-Hyslop P, Mayeux R, Rogaeva E, Alzheimer’s Disease Genetics Consortium. PMID: 26366463; PMCID: PMC4641052.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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A priori collaboration in population imaging: The Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium. Alzheimers Dement (Amst). 2015 Dec; 1(4):513-20.
Adams HH, Hilal S, Schwingenschuh P, Wittfeld K, van der Lee SJ, DeCarli C, Vernooij MW, Katschnig-Winter P, Habes M, Chen C, Seshadri S, van Duijn CM, Ikram MK, Grabe HJ, Schmidt R, Ikram MA. PMID: 27239529; PMCID: PMC4879491.
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PubMed Mentions:
23
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White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke. 2015 Nov; 46(11):3048-57.
Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, Callisaya M, Chauhan G, de Craen AJ, Dufouil C, van Duijn CM, Ford I, Freudenberger P, Gottesman RF, Gudnason V, Heiss G, Hofman A, Lumley T, Martinez O, Mazoyer B, Moran C, Niessen WJ, Phan T, Psaty BM, Satizabal CL, Sattar N, Schilling S, Shibata DK, Slagboom PE, Smith A, Stott DJ, Taylor KD, Thomson R, Töglhofer AM, Tzourio C, van Buchem M, Wang J, Westendorp RG, Windham BG, Vernooij MW, Zijdenbos A, Beare R, Debette S, Ikram MA, Jukema JW, Launer LJ, Longstreth WT, Mosley TH, Seshadri S, Schmidt H, Schmidt R, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. PMID: 26451028; PMCID: PMC4749149.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities. Twin Res Hum Genet. 2015 Dec; 18(6):738-45.
Luciano M, Marioni RE, Valdés Hernández M, Muñoz Maniega S, Hamilton IF, Royle NA, Generation Scotland, Chauhan G, Bis JC, Debette S, DeCarli C, Fornage M, Schmidt R, Ikram MA, Launer LJ, Seshadri S, Bastin ME, Porteous DJ, Wardlaw J, Deary IJ, CHARGE Consortium. PMID: 26427786; PMCID: PMC4747328.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Editorial Transition at Alzheimer's Disease and Associated Disorders. Alzheimer Dis Assoc Disord. 2015 Oct-Dec; 29(4):277-8.
DeCarli C. PMID: 26492327.
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PubMed Mentions: Fields:
Translation:
Humans
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Infectious Burden and Cognitive Decline in the Northern Manhattan Study. J Am Geriatr Soc. 2015 Aug; 63(8):1540-5.
Wright CB, Gardener H, Dong C, Yoshita M, DeCarli C, Sacco RL, Stern Y, Elkind MS. PMID: 26289683; PMCID: PMC4878014.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke. Stroke. 2015 Sep; 46(9):2568-75.
Andersson C, Preis SR, Beiser A, DeCarli C, Wollert KC, Wang TJ, Januzzi JL, Vasan RS, Seshadri S. PMID: 26219649; PMCID: PMC4550531.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Large-scale genomics unveil polygenic architecture of human cortical surface area. Nat Commun. 2015 Jul 20; 6:7549.
Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, Pediatric Imaging Neurocognition and Genetics Study, Alzheimer's Disease Neuroimaging Initiative. PMID: 26189703; PMCID: PMC4518289.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Cognitive correlates of white matter lesion load and brain atrophy: the Northern Manhattan Study. Neurology. 2015 Aug 04; 85(5):441-9.
Dong C, Nabizadeh N, Caunca M, Cheung YK, Rundek T, Elkind MS, DeCarli C, Sacco RL, Stern Y, Wright CB. PMID: 26156514; PMCID: PMC4534076.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansPHPublic Health
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Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56.
Jack CR, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M. PMID: 26194310; PMCID: PMC4523217.
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PubMed Mentions:
70 Fields:
Translation:
Humans
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Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. Ann Neurol. 2015 Aug; 78(2):211-21.
Kao PF, Chen YR, Liu XB, DeCarli C, Seeley WW, Jin LW. PMID: 25921485; PMCID: PMC4822421.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Med. 2015 Jun; 12(6):e1001841; discussion e1001841.
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Alzheimer’s Disease Genetics Consortium, GERAD1 Consortium, EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. PMID: 26079503; PMCID: PMC4469461.
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PubMed Mentions:
104 Fields:
Translation:
Humans
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Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec; 11(12):1480-1488.
Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. PMID: 26079413; PMCID: PMC4677060.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. Alzheimers Dement. 2015 Dec; 11(12):1439-1451.
Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM, Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators, Alzheimer's Disease Genetics Consortium. PMID: 26079416; PMCID: PMC4676945.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Subclinical cerebrovascular disease inversely associates with learning ability: The NOMAS. Neurology. 2015 Jun 09; 84(23):2362-7.
Glazer H, Dong C, Yoshita M, Rundek T, Elkind MS, Sacco RL, DeCarli C, Stern Y, Wright CB. PMID: 26002489; PMCID: PMC4464740.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Blood pressure control and cognitive performance: something to think about with aging. JAMA. 2015 May 19; 313(19):1963-4.
DeCarli C. PMID: 25988465; PMCID: PMC5540364.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nat Commun. 2015 May 19; 6:6760.
Ayton S, Faux NG, Bush AI, Alzheimer's Disease Neuroimaging Initiative. PMID: 25988319; PMCID: PMC4479012.
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PubMed Mentions:
142 Fields:
Translation:
Humans
-
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015 Jul; 138(Pt 7):2020-33.
Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, Madison C, Ayakta N, Ghosh PM, La Joie R, Arthur-Bentil SK, Vogel JW, Marks SM, Lehmann M, Rosen HJ, Reed B, Olichney J, Boxer AL, Miller BL, Borys E, Jin LW, Huang EJ, Grinberg LT, DeCarli C, Seeley WW, Jagust W. PMID: 25953778; PMCID: PMC4806716.
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PubMed Mentions:
213 Fields:
Translation:
Humans
-
Glucose indices are associated with cognitive and structural brain measures in young adults. Neurology. 2015 Jun 09; 84(23):2329-37.
Weinstein G, Maillard P, Himali JJ, Beiser AS, Au R, Wolf PA, Seshadri S, DeCarli C. PMID: 25948725; PMCID: PMC4464744.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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A call for new thoughts about what might influence human brain aging: aging, apolipoprotein E, and amyloid. JAMA Neurol. 2015 May; 72(5):500-2.
DeCarli C. PMID: 25775040; PMCID: PMC4428918.
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PubMed Mentions: Fields:
Translation:
Humans
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Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke. 2015 May; 46(5):1161-6.
Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. PMID: 25908455; PMCID: PMC4414870.
View in:
PubMed Mentions:
106 Fields:
Translation:
HumansPHPublic Health
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A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. JAMA Neurol. 2015 Apr; 72(4):414-22.
Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, Haase CM, Miller J, Poon WW, Rosen A, Rosen H, Sapozhnikova A, Shapira J, Varpetian A, Foroud TM, Levenson RW, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Coppola G. PMID: 25706306; PMCID: PMC4397175.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Chronic Depressive Symptomatology in Mild Cognitive Impairment Is Associated with Frontal Atrophy Rate which Hastens Conversion to Alzheimer Dementia. Am J Geriatr Psychiatry. 2016 Feb; 24(2):126-35.
Sacuiu S, Insel PS, Mueller S, Tosun D, Mattsson N, Jack CR, DeCarli C, Petersen R, Aisen PS, Weiner MW, Mackin RS, Alzheimer's Disease Neuroimaging Initiative. PMID: 26238228; PMCID: PMC4973623.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
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White matter hyperintensities among older adults are associated with futile increase in frontal activation and functional connectivity during spatial search. PLoS One. 2015; 10(3):e0122445.
Lockhart SN, Luck SJ, Geng J, Beckett L, Disbrow EA, Carmichael O, DeCarli C. PMID: 25793922; PMCID: PMC4368687.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study. Am J Alzheimers Dis Other Demen. 2015 Sep; 30(6):622-8.
Libon DJ, Preis SR, Beiser AS, Devine S, Seshadri S, Wolf PA, DeCarli C, Au R. PMID: 25788434; PMCID: PMC4536169.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L, IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. PMID: 25778476; PMCID: PMC4573764.
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PubMed Mentions:
157 Fields:
Translation:
HumansCells
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Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. PLoS One. 2015; 10(3):e0118338.
Yokoyama JS, Lee AK, Takada LT, Busovaca E, Bonham LW, Chao SZ, Tse M, He J, Schwarz CG, Carmichael OT, Matthews BR, Karydas A, Weiner MW, Coppola G, DeCarli CS, Miller BL, Rosen HJ. PMID: 25738563; PMCID: PMC4349764.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet. 2015 Apr; 8(2):398-409.
Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M. PMID: 25663218; PMCID: PMC4427240.
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PubMed Mentions:
93 Fields:
Translation:
HumansCellsCTClinical Trials
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Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16.
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25531812; PMCID: PMC4324097.
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PubMed Mentions:
23 Fields:
Translation:
Humans
-
Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study. Neurology. 2015 Feb 24; 84(8):825-32.
Shoamanesh A, Preis SR, Beiser AS, Vasan RS, Benjamin EJ, Kase CS, Wolf PA, DeCarli C, Romero JR, Seshadri S. PMID: 25632086; PMCID: PMC4345647.
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PubMed Mentions:
95 Fields:
Translation:
Humans
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Cooccurrence of vascular risk factors and late-life white-matter integrity changes. Neurobiol Aging. 2015 Apr; 36(4):1670-1677.
Maillard P, Carmichael OT, Reed B, Mungas D, DeCarli C. PMID: 25666995; PMCID: PMC4380772.
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PubMed Mentions:
20 Fields:
Translation:
Humans
-
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16.
Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. PMID: 25670335; PMCID: PMC4391343.
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PubMed Mentions:
37 Fields:
Translation:
Humans
-
Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(4):1213-29.
Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp FR. PMID: 25697841; PMCID: PMC4422390.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Structural MRI Predictors of Late-Life Cognition Differ Across African Americans, Hispanics, and Whites. Curr Alzheimer Res. 2015; 12(7):632-9.
Zahodne LB, Manly JJ, Narkhede A, Griffith EY, DeCarli C, Schupf NS, Mayeux R, Brickman AM. PMID: 26027808; PMCID: PMC4872300.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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The role of carotid intima-media thickness in predicting longitudinal cognitive function in an older adult cohort. Cerebrovasc Dis. 2014; 38(6):441-7.
Frazier DT, Seider T, Bettcher BM, Mack WJ, Jastrzab L, Chao L, Weiner MW, DeCarli C, Reed BR, Mungas D, Chui HC, Kramer JH. PMID: 25502351; PMCID: PMC4303029.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Alzheimer Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. PMID: 25199842; PMCID: PMC4314944.
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PubMed Mentions:
99 Fields:
Translation:
Humans
-
Donepezil treatment in ethnically diverse patients with Alzheimer disease. Am J Geriatr Psychiatry. 2015 Apr; 23(4):384-390.
Tinklenberg JR, Kraemer HC, Yaffe K, O'Hara R, Ringman JM, Ashford JW, Yesavage JA, Taylor JL, California Alzheimer's Disease Centers. PMID: 25747405; PMCID: PMC4874327.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity. Alzheimers Dement. 2015 Feb; 11(2):111-25.
Frisoni GB, Jack CR, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, deToledo-Morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O'Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deLeon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M, EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzh. PMID: 25267715; PMCID: PMC4422168.
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PubMed Mentions:
86 Fields:
Translation:
Humans
-
Harmonized benchmark labels of the hippocampus on magnetic resonance: the EADC-ADNI project. Alzheimers Dement. 2015 Feb; 11(2):151-60.e5.
Bocchetta M, Boccardi M, Ganzola R, Apostolova LG, Preboske G, Wolf D, Ferrari C, Pasqualetti P, Robitaille N, Duchesne S, Jack CR, Frisoni GB, EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the A. PMID: 25223727.
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PubMed Mentions:
15 Fields:
Translation:
Humans
-
Structural imaging measures of brain aging. Neuropsychol Rev. 2014 Sep; 24(3):271-89.
Lockhart SN, DeCarli C. PMID: 25146995; PMCID: PMC4163469.
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PubMed Mentions:
95 Fields:
Translation:
Humans
-
Neuroimaging of the aging brain: introduction to the special issue of neuropsychology review. Neuropsychol Rev. 2014 Sep; 24(3):267-70.
Lockhart S, DeCarli C, Fama R. PMID: 25146996; PMCID: PMC4262518.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance. Alzheimers Dement. 2015 Feb; 11(2):126-38.
Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack CR, Frisoni GB, EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. PMID: 25130658; PMCID: PMC4419736.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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ERP abnormalities elicited by word repetition in fragile X-associated tremor/ataxia syndrome (FXTAS) and amnestic MCI. Neuropsychologia. 2014 Oct; 63:34-42.
Yang JC, Chi L, Teichholtz S, Schneider A, Nanakul R, Nowacki R, Seritan A, Reed B, DeCarli C, Iragui VJ, Kutas M, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 25111034; PMCID: PMC4194142.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Lipid profile components and subclinical cerebrovascular disease in the northern Manhattan study. Cerebrovasc Dis. 2014; 37(6):423-30.
Willey JZ, Gardener H, Moon YP, Yoshita M, DeCarli C, Cheung YK, Sacco RL, Elkind MS, Wright CB. PMID: 25034465; PMCID: PMC4142052.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):226-33.
Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp FR. PMID: 24731980; PMCID: PMC4139468.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Association between neuropathology and brain volume in the Framingham Heart Study. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):219-25.
Kaur B, Himali JJ, Seshadri S, Beiser AS, Au R, McKee AC, Auerbach S, Wolf PA, DeCarli CS. PMID: 24614264; PMCID: PMC4139422.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Vascular risk and Aβ interact to reduce cortical thickness in AD vulnerable brain regions. Neurology. 2014 Jul 01; 83(1):40-7.
Villeneuve S, Reed BR, Madison CM, Wirth M, Marchant NL, Kriger S, Mack WJ, Sanossian N, DeCarli C, Chui HC, Weiner MW, Jagust WJ. PMID: 24907234; PMCID: PMC4114172.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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Early Brain Loss in Circuits Affected by Alzheimer's Disease is Predicted by Fornix Microstructure but may be Independent of Gray Matter. Front Aging Neurosci. 2014; 6:106.
Fletcher E, Carmichael O, Pasternak O, Maier-Hein KH, DeCarli C. PMID: 24904414; PMCID: PMC4035735.
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PubMed Mentions:
25
-
Migraine, white matter hyperintensities, and subclinical brain infarction in a diverse community: the northern Manhattan study. Stroke. 2014 Jun; 45(6):1830-2.
Monteith T, Gardener H, Rundek T, Dong C, Yoshita M, Elkind MS, DeCarli C, Sacco RL, Wright CB. PMID: 24876263; PMCID: PMC4049191.
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PubMed Mentions:
27 Fields:
Translation:
HumansCTClinical Trials
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Response to letter regarding article, "subclinical left ventricular dysfunction and silent cerebrovascular disease: the cardiovascular abnormalities and brain lesions (CABL) study". Circulation. 2014 May 06; 129(18):e486-7.
Russo C, Jin Z, Homma S, Elkind MS, Rundek T, Yoshita M, Decarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 24799510.
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PubMed Mentions: Fields:
Translation:
Humans
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White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain. Stroke. 2014 Jun; 45(6):1721-6.
Maillard P, Fletcher E, Lockhart SN, Roach AE, Reed B, Mungas D, DeCarli C, Carmichael OT. PMID: 24781079; PMCID: PMC4102626.
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PubMed Mentions:
89 Fields:
Translation:
HumansCTClinical Trials
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Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke. 2014 May; 45(5):1492-4.
Romero JR, Preis SR, Beiser A, DeCarli C, Viswanathan A, Martinez-Ramirez S, Kase CS, Wolf PA, Seshadri S. PMID: 24713533; PMCID: PMC4048617.
View in:
PubMed Mentions:
123 Fields:
Translation:
Humans
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Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014 May 06; 82(18):1613-9.
Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. PMID: 24706014; PMCID: PMC4013812.
View in:
PubMed Mentions:
102 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Associations between serum cholesterol levels and cerebral amyloidosis. JAMA Neurol. 2014 Feb; 71(2):195-200.
Reed B, Villeneuve S, Mack W, DeCarli C, Chui HC, Jagust W. PMID: 24378418; PMCID: PMC4083819.
View in:
PubMed Mentions:
111 Fields:
Translation:
Humans
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Cortical thickness mediates the effect of β-amyloid on episodic memory. Neurology. 2014 Mar 04; 82(9):761-7.
Villeneuve S, Reed BR, Wirth M, Haase CM, Madison CM, Ayakta N, Mack W, Mungas D, Chui HC, DeCarli C, Weiner MW, Jagust WJ. PMID: 24489134; PMCID: PMC3945649.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Mar; 127(3):407-18.
Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, DeCarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White CL, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin AS. PMID: 24442578; PMCID: PMC4003885.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014 Feb; 45(2):403-12.
Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, Schmidt H, Lahti J, Heckbert SR, Lumley T, Rice K, Rotter JI, Taylor KD, Folsom AR, Boerwinkle E, Rosamond WD, Shahar E, Gottesman RF, Koudstaal PJ, Amin N, Wieberdink RG, Dehghan A, Hofman A, Uitterlinden AG, Destefano AL, Debette S, Xue L, Beiser A, Wolf PA, Decarli C, Ikram MA, Seshadri S, Mosley TH, Longstreth WT, van Duijn CM, Launer LJ. PMID: 24436238; PMCID: PMC3955258.
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PubMed Mentions:
39 Fields:
Translation:
Humans
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Biological heterogeneity in ADNI amnestic mild cognitive impairment. Alzheimers Dement. 2014 Sep; 10(5):511-521.e1.
Nettiksimmons J, DeCarli C, Landau S, Beckett L, Alzheimer's Disease Neuroimaging Initiative. PMID: 24418061; PMCID: PMC4092059.
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PubMed Mentions:
67 Fields:
Translation:
Humans
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Longitudinal trajectories of everyday function by diagnostic status. Psychol Aging. 2013 Dec; 28(4):1070-5.
Farias ST, Chou E, Harvey DJ, Mungas D, Reed B, DeCarli C, Park LQ, Beckett L. PMID: 24364409; PMCID: PMC4021720.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Parental longevity is associated with cognition and brain ageing in middle-aged offspring. Age Ageing. 2014 May; 43(3):358-63.
Murabito JM, Beiser AS, Decarli C, Seshadri S, Wolf PA, Au R. PMID: 24212919; PMCID: PMC4001170.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals. JAMA Neurol. 2013 Nov; 70(11):1389-95.
Fletcher E, Raman M, Huebner P, Liu A, Mungas D, Carmichael O, DeCarli C. PMID: 24018960; PMCID: PMC4059679.
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PubMed Mentions:
69 Fields:
Translation:
HumansCells
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White matter hyperintensities are associated with visual search behavior independent of generalized slowing in aging. Neuropsychologia. 2014 Jan; 52:93-101.
Lockhart SN, Roach AE, Luck SJ, Geng J, Beckett L, Carmichael O, DeCarli C. PMID: 24183716; PMCID: PMC3924853.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Amylin: what might be its role in Alzheimer's disease and how could this affect therapy? Expert Rev Proteomics. 2013 Oct; 10(5):403-5.
Despa F, Decarli C. PMID: 24117198; PMCID: PMC4068803.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Alcohol intake and brain structure in a multiethnic elderly cohort. Clin Nutr. 2014 Aug; 33(4):662-7.
Gu Y, Scarmeas N, Short EE, Luchsinger JA, DeCarli C, Stern Y, Manly JJ, Schupf N, Mayeux R, Brickman AM. PMID: 24011900; PMCID: PMC4048329.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Relations of arterial stiffness and endothelial function to brain aging in the community. Neurology. 2013 Sep 10; 81(11):984-91.
Tsao CW, Seshadri S, Beiser AS, Westwood AJ, Decarli C, Au R, Himali JJ, Hamburg NM, Vita JA, Levy D, Larson MG, Benjamin EJ, Wolf PA, Vasan RS, Mitchell GF. PMID: 23935179; PMCID: PMC3888200.
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PubMed Mentions:
130 Fields:
Translation:
HumansCells
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Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke. 2013 Oct; 44(10):2768-75.
Pikula A, Beiser AS, Chen TC, Preis SR, Vorgias D, DeCarli C, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. PMID: 23929745; PMCID: PMC3873715.
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PubMed Mentions:
75 Fields:
Translation:
HumansCTClinical Trials
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Brain imaging and cognitive predictors of stroke and Alzheimer disease in the Framingham Heart Study. Stroke. 2013 Oct; 44(10):2787-94.
Weinstein G, Beiser AS, Decarli C, Au R, Wolf PA, Seshadri S. PMID: 23920020; PMCID: PMC3974341.
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PubMed Mentions:
22 Fields:
Translation:
HumansCTClinical Trials
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Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013 Aug; 12(8):822-38.
Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, Lindley RI, O'Brien JT, Barkhof F, Benavente OR, Black SE, Brayne C, Breteler M, Chabriat H, Decarli C, de Leeuw FE, Doubal F, Duering M, Fox NC, Greenberg S, Hachinski V, Kilimann I, Mok V, Oostenbrugge Rv, Pantoni L, Speck O, Stephan BC, Teipel S, Viswanathan A, Werring D, Chen C, Smith C, van Buchem M, Norrving B, Gorelick PB, Dichgans M, STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1). PMID: 23867200; PMCID: PMC3714437.
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PubMed Mentions:
2192 Fields:
Translation:
Humans
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Dissociable effects of Alzheimer disease and white matter hyperintensities on brain metabolism. JAMA Neurol. 2013 Aug; 70(8):1039-45.
Haight TJ, Landau SM, Carmichael O, Schwarz C, DeCarli C, Jagust WJ, Alzheimer's Disease Neuroimaging Initiative. PMID: 23779022; PMCID: PMC3779687.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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Subclinical left ventricular dysfunction and silent cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Circulation. 2013 Sep 03; 128(10):1105-11.
Russo C, Jin Z, Homma S, Elkind MS, Rundek T, Yoshita M, DeCarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 23902759; PMCID: PMC4370621.
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PubMed Mentions:
30 Fields:
Translation:
HumansPHPublic Health
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Imaging markers for Alzheimer disease: which vs how. Neurology. 2013 Jul 30; 81(5):487-500.
Frisoni GB, Bocchetta M, Chételat G, Rabinovici GD, de Leon MJ, Kaye J, Reiman EM, Scheltens P, Barkhof F, Black SE, Brooks DJ, Carrillo MC, Fox NC, Herholz K, Nordberg A, Jack CR, Jagust WJ, Johnson KA, Rowe CC, Sperling RA, Thies W, Wahlund LO, Weiner MW, Pasqualetti P, Decarli C, ISTAART's NeuroImaging Professional Interest Area. PMID: 23897875; PMCID: PMC3776529.
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PubMed Mentions:
80 Fields:
Translation:
Humans
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Quantifying cognitive reserve in older adults by decomposing episodic memory variance: replication and extension. J Int Neuropsychol Soc. 2013 Sep; 19(8):854-62.
Zahodne LB, Manly JJ, Brickman AM, Siedlecki KL, Decarli C, Stern Y. PMID: 23866160; PMCID: PMC3777696.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology. 2013 Jul 16; 81(3):292-300.
Schilling S, DeStefano AL, Sachdev PS, Choi SH, Mather KA, DeCarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. PMID: 23858411; PMCID: PMC3770168.
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PubMed Mentions:
88 Fields:
Translation:
Humans
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Amylin deposition in the brain: A second amyloid in Alzheimer disease? Ann Neurol. 2013 Oct; 74(4):517-26.
Jackson K, Barisone GA, Diaz E, Jin LW, DeCarli C, Despa F. PMID: 23794448; PMCID: PMC3818462.
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PubMed Mentions:
179 Fields:
Translation:
Humans
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Extrapyramidal signs by dementia severity in Alzheimer disease and dementia with Lewy bodies. Alzheimer Dis Assoc Disord. 2013 Jul-Sep; 27(3):226-32.
Kaur B, Harvey DJ, Decarli CS, Zhang L, Sabbagh MN, Olichney JM. PMID: 23023095; PMCID: PMC3562426.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Associations between white matter hyperintensities and β amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor MRI. PLoS One. 2013; 8(6):e65175.
Chao LL, Decarli C, Kriger S, Truran D, Zhang Y, Laxamana J, Villeneuve S, Jagust WJ, Sanossian N, Mack WJ, Chui HC, Weiner MW. PMID: 23762308; PMCID: PMC3675157.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics. 2013 Jun 1; 45(6):713-713.
Taal TH, St Pourcain SB, Thiering TE, Das DS, Mook-Kanamori MD, Warrington WN, Kaakinen KM, Kreiner-Møller KE, Bradfield BJ, Freathy FR, Geller GF, Guxens GM, Cousminer CD, Kerkhof KM, Timpson TN, Ikram IM, Beilin BL, Bønnelykke BK, Buxton BJ, Charoen CP, Chawes CB, Eriksson EJ, Evans ED, Hofman HA, Kemp KJ, Kim KC, Klopp KN, Lahti LJ, Lye LS, McMahon MG, Mentch MF, Müller-Nurasyid MM, O'Reilly OP, Prokopenko PI, Rivadeneira RF, Steegers SE, Sunyer SJ, Tiesler TC, Yaghootkar YH, , Breteler BM, Debette DS, Fornage FM, Gudnason GV, Launer LL, van der Lugt vA, Mosley MT, Seshadri SS, Smith SA, Vernooij VM, , Blakemore BA, Chiavacci CR, Feenstra FB, Fernandez-Banet FJ, Grant GS, Hartikainen HA, van der Heijden vA, Iñiguez IC, Lathrop LM, McArdle MW, Mølgaard MA, Newnham NJ, Palmer PL, Palotie PA, Pouta PA, Ring RS, Sovio SU, Standl SM, Uitterlinden UA, Wichmann WH, Vissing VN, DeCarli DC, van Duijn vC, McCarthy MM, Koppelman KG, Estivill EX, Hattersley HA, Melbye MM, Bisgaard BH, Pennell PC, Widen WE, Hakonarson HH, Smith SG, Heinrich HJ, Jarvelin JM, Jaddoe JV, . .
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Patent foramen ovale, subclinical cerebrovascular disease, and ischemic stroke in a population-based cohort. J Am Coll Cardiol. 2013 Jul 02; 62(1):35-41.
Di Tullio MR, Jin Z, Russo C, Elkind MS, Rundek T, Yoshita M, DeCarli C, Wright CB, Homma S, Sacco RL. PMID: 23644084; PMCID: PMC3696432.
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PubMed Mentions:
21 Fields:
Translation:
HumansPHPublic Health
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The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction. JAMA Neurol. 2013 Apr; 70(4):488-95.
Marchant NL, Reed BR, Sanossian N, Madison CM, Kriger S, Dhada R, Mack WJ, DeCarli C, Weiner MW, Mungas DM, Chui HC, Jagust WJ. PMID: 23400560; PMCID: PMC3771392.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Ventricular enlargement and its clinical correlates in the imaging cohort from the ADCS MCI donepezil/vitamin E study. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):174-81.
Apostolova LG, Babakchanian S, Hwang KS, Green AE, Zlatev D, Chou YY, DeCarli C, Jack CR, Petersen RC, Aisen PS, Cummings JL, Toga AW, Thompson PM. PMID: 23694947; PMCID: PMC3662002.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls. Neurobiol Aging. 2013 Aug; 34(8):1996-2002.
Barnes J, Carmichael OT, Leung KK, Schwarz C, Ridgway GR, Bartlett JW, Malone IB, Schott JM, Rossor MN, Biessels GJ, DeCarli C, Fox NC, Alzheimer's Disease Neuroimaging Initiative. PMID: 23522844; PMCID: PMC3810644.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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Effects of T2-Weighted MRI Based Cranial Volume Measurements on Studies of the Aging Brain. Proc SPIE Int Soc Opt Eng. 2013 Mar 13; 8669.
Vuong P, Drucker D, Schwarz C, Fletcher E, Decarli C, Carmichael O. PMID: 24353391; PMCID: PMC3864960.
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PubMed Mentions:
4
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LA volumes and reservoir function are associated with subclinical cerebrovascular disease: the CABL (Cardiovascular Abnormalities and Brain Lesions) study. JACC Cardiovasc Imaging. 2013 Mar; 6(3):313-23.
Russo C, Jin Z, Liu R, Iwata S, Tugcu A, Yoshita M, Homma S, Elkind MS, Rundek T, Decarli C, Wright CB, Sacco RL, Di Tullio MR. PMID: 23473112; PMCID: PMC3600634.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Subgroup of ADNI normal controls characterized by atrophy and cognitive decline associated with vascular damage. Psychol Aging. 2013 Mar; 28(1):191-201.
Nettiksimmons J, Beckett L, Schwarz C, Carmichael O, Fletcher E, Decarli C. PMID: 23527743; PMCID: PMC3751169.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Course and etiology of dysexecutive MCI in a community sample. Alzheimers Dement. 2013 Nov; 9(6):632-9.
Huey ED, Manly JJ, Tang MX, Schupf N, Brickman AM, Manoochehri M, Mez J, DeCarli C, Devanand DP, Mayeux R. PMID: 23452959; PMCID: PMC3933297.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Demographic predictors of cognitive change in ethnically diverse older persons. Psychol Aging. 2013 Sep; 28(3):633-45.
Early DR, Widaman KF, Harvey D, Beckett L, Park LQ, Farias ST, Reed BR, Decarli C, Mungas D. PMID: 23437898; PMCID: PMC3778107.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Association of parental stroke with brain injury and cognitive measures in offspring: the Framingham Heart Study. Stroke. 2013 Mar; 44(3):812-5.
Weinstein G, Beiser AS, Au R, Decarli C, Wolf PA, Seshadri S. PMID: 23362080; PMCID: PMC3752976.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Perceived stress is associated with subclinical cerebrovascular disease in older adults. Am J Geriatr Psychiatry. 2014 Jan; 22(1):53-62.
Aggarwal NT, Clark CJ, Beck TL, Mendes de Leon CF, DeCarli C, Evans DA, Everson Rose SA. PMID: 23567443; PMCID: PMC3707931.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Globally optimal cortical surface matching with exact landmark correspondence. Inf Process Med Imaging. 2013; 23:487-98.
Tsui A, Fenton D, Vuong P, Hass J, Koehl P, Amenta N, Coeurjolly D, DeCarli C, Carmichael O. PMID: 24683993; PMCID: PMC4412256.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Clinically asymptomatic vascular brain injury: a potent cause of cognitive impairment among older individuals. J Alzheimers Dis. 2013; 33 Suppl 1:S417-26.
DeCarli C. PMID: 23034523; PMCID: PMC3786369.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Relationship between baseline brain metabolism measured using [¹⁸F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease. Brain Imaging Behav. 2012 Dec; 6(4):568-83.
Habeck C, Risacher S, Lee GJ, Glymour MM, Mormino E, Mukherjee S, Kim S, Nho K, DeCarli C, Saykin AJ, Crane PK, Alzheimer’s Disease Neuroimaging Initiative. PMID: 23179062; PMCID: PMC3532575.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease. Brain Imaging Behav. 2012 Dec; 6(4):551-67.
Nho K, Risacher SL, Crane PK, DeCarli C, Glymour MM, Habeck C, Kim S, Lee GJ, Mormino E, Mukherjee S, Shen L, West JD, Saykin AJ, Alzheimer’s Disease Neuroimaging Initiative--ADNI. PMID: 23070747; PMCID: PMC3532574.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Genetic architecture of resilience of executive functioning. Brain Imaging Behav. 2012 Dec; 6(4):621-33.
Mukherjee S, Kim S, Gibbons LE, Nho K, Risacher SL, Glymour MM, Habeck C, Lee GJ, Mormino E, Ertekin-Taner N, Montine TJ, Decarli C, Saykin AJ, Crane PK, Alzheimer’s Disease Neuroimaging Initiative. PMID: 22711244; PMCID: PMC3607298.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.
Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alzheimer's Disease Genetics Consortium, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. PMID: 23143602; PMCID: PMC3510344.
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PubMed Mentions:
128 Fields:
Translation:
Humans
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Next frontiers in the genetic epidemiology of Alzheimer's disease. Eur J Epidemiol. 2012 Nov; 27(11):831-6.
Ikram MA, DeCarli C. PMID: 23132737; PMCID: PMC3774602.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study. Lancet Neurol. 2012 Dec; 11(12):1039-47.
Maillard P, Seshadri S, Beiser A, Himali JJ, Au R, Fletcher E, Carmichael O, Wolf PA, DeCarli C. PMID: 23122892; PMCID: PMC3510663.
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PubMed Mentions:
151 Fields:
Translation:
HumansCells
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Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimers Dement. 2013 May; 9(3):332-7.
Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, DeCarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR, Alzheimer’s Disease Neuroimaging Initiative. PMID: 23110865; PMCID: PMC3891834.
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PubMed Mentions:
94 Fields:
Translation:
Humans
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