Bradley P Ander

Title(s)Associate Adjunct Professor, Med: Neurology
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of Winnipeg, Winnipeg, Manitoba, CanadaBSc05/1999Biochemistry
    University of Manitoba, Winnipeg. Manitoba, CanadaPhD09/2006Physiology
    University of California at Davis, Davis, California, United StatesMBA06/2018Analytics, Organizational Behaviour

    Collapse Overview 
    Collapse Overview
    Dr. Ander is interested in understanding the gene expression response after brain injury. He studies the relationships between different types of RNA molecules and how we can use this knowledge to improve therapies and treatment. He also looks at how individual genetic variation can contribute to unique transcriptional responses of RNA.

    Ribonucleic acids (RNA) are the intermediary between DNA and protein, and they are highly dynamic in response to disease or injury. The interplay between coding and non-coding transcripts ultimately regulates and gives rise to biological processes and functions that allow complex cellular systems to function. In the transition from normal to pathophysiological condition, the balance of these interactions can shift. As we learn more about how these interactions are regulated, we can also focus on developing molecular interventions that improve health.

    Dr. Ander has studied gene expression in neurological, neurodevelopmental and neurodegenerative disorders such as stroke, autism and Alzheimer’s disease incorporating the latest bioinformatics tools and techniques to analyze these and other disorders with his collaborators.

    Collapse Research 
    Collapse Research Activities and Funding
    Biomarker Signatures for Delayed Cerebral Ischemia and Outcome Following Subarachnoid Hemorrhage
    NIH R61NS119345Jan 1, 2021 - Dec 31, 2025
    Role: Co-Principal Investigator
    Genomics of Intracerebral Hemorrhage and its Causes
    NIH R01NS106950Apr 1, 2019 - Jan 31, 2024
    Role: Co-Principal Investigator
    Whole Genome RNA Sequencing (RNAseq) of Blood from Patients with Lacunar Stroke
    NIH R01NS101718Sep 1, 2017 - May 31, 2022
    Role: Co-Investigator
    Whole Transcriptome Studies of Patients with Transient Ischemic Attacks (TIAs)
    NIH R01NS097000Apr 1, 2016 - Mar 31, 2021
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ischemic Stroke with Comorbid Cancer Has Specific miRNA-mRNA Networks in Blood That Vary by Ischemic Stroke Mechanism. Ann Neurol. 2024 Sep; 96(3):565-581. Knepp B, Navi BB, Rodriguez F, DeAngelis LM, Elkind MSV, Iadecola C, Sherman CP, Tagawa ST, Saxena A, Ocean AJ, Hull H, Jickling G, Sharp FR, Ander BP, Stamova B. PMID: 38874304.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex. Proc Natl Acad Sci U S A. 2023 03 07; 120(10):e2206758120. Zhang P, Omanska A, Ander BP, Gandal MJ, Stamova B, Schumann CM. PMID: 36862688; PMCID: PMC10013873.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    3. Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke. BMC Med. 2023 02 20; 21(1):65. Carmona-Mora P, Knepp B, Jickling GC, Zhan X, Hakoupian M, Hull H, Alomar N, Amini H, Sharp FR, Stamova B, Ander BP. PMID: 36803375; PMCID: PMC9942321.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    4. Early peripheral blood gene expression associated with good and poor 90-day ischemic stroke outcomes. J Neuroinflammation. 2023 Jan 23; 20(1):13. Amini H, Knepp B, Rodriguez F, Jickling GC, Hull H, Carmona-Mora P, Bushnell C, Ander BP, Sharp FR, Stamova B. PMID: 36691064; PMCID: PMC9869610.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    5. Progression of cerebral white matter hyperintensities is related to leucocyte gene expression. Brain. 2022 09 14; 145(9):3179-3186. Jickling GC, Ander BP, Zhan X, Stamova B, Hull H, DeCarli C, Sharp FR. PMID: 35325079; PMCID: PMC10233292.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    6. Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke. Brain. 2022 07 29; 145(7):2394-2406. Ibanez L, Heitsch L, Carrera C, Farias FHG, Del Aguila JL, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R, Viana Oliveira Souza AA, Moniche F, Cabezas-Juan A, Arenillas JF, Krupinksi J, Cullell N, Torres-Aguila N, Muiño E, Cárcel-Márquez J, Marti-Fabregas J, Delgado-Mederos R, Marin-Bueno R, Hornick A, Vives-Bauza C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano-Heras G, Chung JW, Roquer J, Soriano-Tarraga C, Giralt-Steinhauer E, Mola-Caminal M, Pera J, Lapicka-Bodzioch K, Derbisz J, Davalos A, Lopez-Cancio E, Muñoz L, Tatlisumak T, Molina C, Ribo M, Bustamante A, Sobrino T, Castillo-Sanchez J, Campos F, Rodriguez-Castro E, Arias-Rivas S, Rodríguez-Yáñez M, Herbosa C, Ford AL, Gutierrez-Romero A, Uribe-Pacheco R, Arauz A, Lopes-Cendes I, Lowenkopf T, Barboza MA, Amini H, Stamova B, Ander BP, Sharp FR, Kim GM, Bang OY, Jimenez-Conde J, Slowik A, Stribian D, Tsai EA, Burkly LC, Montaner J, Fernandez-Cadenas I, Lee JM, Cruchaga C. PMID: 35213696; PMCID: PMC9890452.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    7. Sustained ICP Elevation Is a Driver of Spatial Memory Deficits After Intraventricular Hemorrhage and Leads to Activation of Distinct Microglial Signaling Pathways. Transl Stroke Res. 2023 08; 14(4):572-588. Puglisi CH, Ander BP, Peterson C, Keiter JA, Hull H, Hawk CW, Kalistratova VS, Izadi A, Gurkoff GG, Sharp FR, Waldau B. PMID: 35821378; PMCID: PMC9834439.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Gene expression changes implicate specific peripheral immune responses to Deep and Lobar Intracerebral Hemorrhages in humans. Brain Hemorrhages. 2022 Dec; 3(4):155-176. Knepp B, Ander BP, Jickling GC, Hull H, Yee AH, Ng K, Rodriguez F, Carmona-Mora P, Amini H, Zhan X, Hakoupian M, Alomar N, Sharp FR, Stamova B. PMID: 36936603; PMCID: PMC10019834.
      View in: PubMed   Mentions:
    9. Combined Inhibition of Fyn and c-Src Protects Hippocampal Neurons and Improves Spatial Memory via ROCK after Traumatic Brain Injury. J Neurotrauma. 2022 04; 39(7-8):520-529. Ye Z, Izadi A, Gurkoff GG, Rickerl K, Sharp FR, Ander BP, Bauer SZ, Lui A, Lyeth BG, Liu D. PMID: 35109711; PMCID: PMC8978569.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    10. Bacterial lipopolysaccharide is associated with stroke. Sci Rep. 2021 03 22; 11(1):6570. Hakoupian M, Ferino E, Jickling GC, Amini H, Stamova B, Ander BP, Alomar N, Sharp FR, Zhan X. PMID: 33753837; PMCID: PMC7985504.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    11. Aging Immune System in Acute Ischemic Stroke: A Transcriptomic Analysis. Stroke. 2021 04; 52(4):1355-1361. Sykes GP, Kamtchum-Tatuene J, Falcione S, Zehnder S, Munsterman D, Stamova B, Ander BP, Sharp FR, Jickling G. PMID: 33641386; PMCID: PMC8011932.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    12. Ras/MAPK dysregulation in development causes a skeletal myopathy in an activating BrafL597V mouse model for cardio-facio-cutaneous syndrome. Dev Dyn. 2021 08; 250(8):1074-1095. Maeda Y, Tidyman WE, Ander BP, Pritchard CA, Rauen KA. PMID: 33522658.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    13. Molecular Correlates of Hemorrhage and Edema Volumes Following Human Intracerebral Hemorrhage Implicate Inflammation, Autophagy, mRNA Splicing, and T Cell Receptor Signaling. Transl Stroke Res. 2021 10; 12(5):754-777. Durocher M, Knepp B, Yee A, Jickling G, Rodriguez F, Ng K, Zhan X, Hamade F, Ferino E, Amini H, Carmona-Mora P, Hull H, Ander BP, Sharp FR, Stamova B. PMID: 33206327; PMCID: PMC8421315.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    14. Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke. medRxiv. 2020 Nov 03. Ibanez L, Heitsch L, Carrera C, Farias FHG, Dhar R, Budde J, Bergmann K, Bradley J, Harari O, Phuah CL, Lemmens R, Souza AAVO, Moniche F, Cabezas-Juan A, Arenillas JF, Krupinksi J, Cullell N, Torres-Aguila N, Muiño E, Cárcel-Márquez J, Marti-Fabregas J, Delgado-Mederos R, Marin-Bueno R, Hornick A, Vives-Bauza C, Navarro RD, Tur S, Jimenez C, Obach V, Segura T, Serrano-Heras G, Chung JW, Roquer J, Soriano-Tarraga C, Giralt-Steinhauer E, Mola-Caminal M, Pera J, Lapicka-Bodzioch K, Derbisz J, Davalos A, Lopez-Cancio E, Muñoz L, Tatlisumak T, Molina C, Ribo M, Bustamante A, Sobrino T, Castillo-Sanchez J, Campos F, Rodriguez-Castro E, Arias-Rivas S, Rodríguez-Yáñez M, Herbosa C, Ford AL, Arauz A, Lopes-Cendes I, Lowenkopf T, Barboza MA, Amini H, Stamova B, Ander BP, Sharp FR, Kim GM, Bang OY, Jimenez-Conde J, Slowik A, Stribian D, Tsai EA, Burkly LC, Montaner J, Fernandez-Cadenas I, Lee JM, Cruchaga C. PMID: 33173895; PMCID: PMC7654887.
      View in: PubMed   Mentions: 1  
    15. Alternative Splicing of Putative Stroke/Vascular Risk Factor Genes Expressed in Blood Following Ischemic Stroke Is Sexually Dimorphic and Cause-Specific. Front Neurol. 2020; 11:584695. Dykstra-Aiello C, Sharp FR, Jickling GC, Hull H, Hamade F, Shroff N, Durocher M, Cheng X, Zhan X, Liu D, Ander BP, Stamova BS. PMID: 33193047; PMCID: PMC7642687.
      View in: PubMed   Mentions: 5  
    16. Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke. J Cereb Blood Flow Metab. 2021 06; 41(6):1398-1416. Carmona-Mora P, Ander BP, Jickling GC, Dykstra-Aiello C, Zhan X, Ferino E, Hamade F, Amini H, Hull H, Sharp FR, Stamova B. PMID: 32960689; PMCID: PMC8142129.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    17. Genetic variation contributes to gene expression response in ischemic stroke: an eQTL study. Ann Clin Transl Neurol. 2020 09; 7(9):1648-1660. Amini H, Shroff N, Stamova B, Ferino E, Carmona-Mora P, Zhan X, Sitorus PP, Hull H, Jickling GC, Sharp FR, Ander BP. PMID: 32785988; PMCID: PMC7480928.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Therapeutic effect of methane and its mechanism in disease treatment. J Zhejiang Univ Sci B. 2020 Aug.; 21(8):593-602. Ye ZH, Ning K, Ander BP, Sun XJ. PMID: 32748575; PMCID: PMC7445089.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. mRNA Expression Profiles from Whole Blood Associated with Vasospasm in Patients with Subarachnoid Hemorrhage. Neurocrit Care. 2020 08; 33(1):82-89. Xu H, Stamova B, Ander BP, Waldau B, Jickling GC, Sharp FR, Ko NU. PMID: 31595394; PMCID: PMC7392923.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile. Stroke. 2019 11; 50(11):3259-3264. Navi BB, Mathias R, Sherman CP, Wolfe J, Kamel H, Tagawa ST, Saxena A, Ocean AJ, Iadecola C, DeAngelis LM, Elkind MSV, Hull H, Jickling GC, Sharp FR, Ander BP, Stamova B. PMID: 31510897; PMCID: PMC6817410.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsCTClinical Trials
    21. Smoking affects gene expression in blood of patients with ischemic stroke. Ann Clin Transl Neurol. 2019 09; 6(9):1748-1756. Cheng X, Ferino E, Hull H, Jickling GC, Ander BP, Stamova B, Sharp FR. PMID: 31436916; PMCID: PMC6764500.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    22. MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage. J Cereb Blood Flow Metab. 2020 04; 40(4):775-786. Cheng X, Ander BP, Jickling GC, Zhan X, Hull H, Sharp FR, Stamova B. PMID: 30966854; PMCID: PMC7168793.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    23. Inflammatory, regulatory, and autophagy co-expression modules and hub genes underlie the peripheral immune response to human intracerebral hemorrhage. J Neuroinflammation. 2019 Mar 05; 16(1):56. Durocher M, Ander BP, Jickling G, Hamade F, Hull H, Knepp B, Liu DZ, Zhan X, Tran A, Cheng X, Ng K, Yee A, Sharp FR, Stamova B. PMID: 30836997; PMCID: PMC6399982.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    24. MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats. Front Neurosci. 2018; 12:767. Lv B, Cheng X, Sharp FR, Ander BP, Liu DZ. PMID: 30405345; PMCID: PMC6207613.
      View in: PubMed   Mentions: 6  
    25. HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke. Transl Stroke Res. 2019 02; 10(1):19-25. Shroff N, Ander BP, Zhan X, Stamova B, Liu D, Hull H, Hamade FR, Dykstra-Aiello C, Ng K, Sharp FR, Jickling GC. PMID: 29651704; PMCID: PMC6186202.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    26. The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes. J Cereb Blood Flow Metab. 2019 09; 39(9):1818-1835. Stamova B, Ander BP, Jickling G, Hamade F, Durocher M, Zhan X, Liu DZ, Cheng X, Hull H, Yee A, Ng K, Shroff N, Sharp FR. PMID: 29651892; PMCID: PMC6727143.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    27. Cleaved β-Actin May Contribute to DNA Fragmentation Following Very Brief Focal Cerebral Ischemia. J Neuropathol Exp Neurol. 2018 03 01; 77(3):260-265. Ye Z, Ander BP, Sharp FR, Zhan X. PMID: 29408985; PMCID: PMC6692854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    28. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. Mol Autism. 2017; 8:4. Schumann CM, Sharp FR, Ander BP, Stamova B. PMID: 28184278; PMCID: PMC5294827.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    29. Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci. Stroke. 2016 12; 47(12):2896-2903. Dykstra-Aiello C, Jickling GC, Ander BP, Shroff N, Zhan X, Liu D, Hull H, Orantia M, Stamova BS, Sharp FR. PMID: 27834745; PMCID: PMC5127755.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    30. Leukocyte response is regulated by microRNA let7i in patients with acute ischemic stroke. Neurology. 2016 Nov 22; 87(21):2198-2205. Jickling GC, Ander BP, Shroff N, Orantia M, Stamova B, Dykstra-Aiello C, Hull H, Zhan X, Liu D, Sharp FR. PMID: 27784773; PMCID: PMC5123554.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    31. Inhibition of Src family kinases improves cognitive function after intraventricular hemorrhage or intraventricular thrombin. J Cereb Blood Flow Metab. 2017 Jul; 37(7):2359-2367. Liu DZ, Waldau B, Ander BP, Zhan X, Stamova B, Jickling GC, Lyeth BG, Sharp FR. PMID: 27624844; PMCID: PMC5531336.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    32. Src Family Kinases in Brain Edema After Acute Brain Injury. Acta Neurochir Suppl. 2016; 121:185-90. Liu D, Zhang X, Hu B, Ander BP. PMID: 26463946; PMCID: PMC5100806.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab. 2016 08; 36(8):1374-83. Liu da Z, Jickling GC, Ander BP, Hull H, Zhan X, Cox C, Shroff N, Dykstra-Aiello C, Stamova B, Sharp FR. PMID: 26661204; PMCID: PMC4976655.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    34. MicroRNA and mRNA Expression Changes in Steroid Naïve and Steroid Treated DMD Patients. J Neuromuscul Dis. 2015 Sep 22; 2(4):387-396. Liu DZ, Stamova B, Hu S, Ander BP, Jickling GC, Zhan X, Sharp FR, Wong B. PMID: 27858746; PMCID: PMC5240570.
      View in: PubMed   Mentions: 7     Fields:    
    35. Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains. J Child Neurol. 2015 Dec; 30(14):1930-46. Stamova B, Ander BP, Barger N, Sharp FR, Schumann CM. PMID: 26350727; PMCID: PMC4647182.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    36. Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. Mol Autism. 2015; 6:37. Ander BP, Barger N, Stamova B, Sharp FR, Schumann CM. PMID: 26146533; PMCID: PMC4491207.
      View in: PubMed   Mentions: 39     Fields:    
    37. Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study. Transl Stroke Res. 2015 Aug; 6(4):284-9. Dykstra-Aiello C, Jickling GC, Ander BP, Zhan X, Liu D, Hull H, Orantia M, Ho C, Stamova B. PMID: 25994285; PMCID: PMC4485700.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    38. Targeting neutrophils in ischemic stroke: translational insights from experimental studies. J Cereb Blood Flow Metab. 2015 Jun; 35(6):888-901. Jickling GC, Liu D, Ander BP, Stamova B, Zhan X, Sharp FR. PMID: 25806703; PMCID: PMC4640255.
      View in: PubMed   Mentions: 262     Fields:    Translation:HumansAnimalsCells
    39. Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. J Alzheimers Dis. 2015; 46(2):507-23. Zhan X, Cox C, Ander BP, Liu D, Stamova B, Jin LW, Jickling GC, Sharp FR. PMID: 25790832; PMCID: PMC4878315.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    40. Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(4):1213-29. Zhan X, Jickling GC, Ander BP, Stamova B, Liu D, Kao PF, Zelin MA, Jin LW, DeCarli C, Sharp FR. PMID: 25697841; PMCID: PMC4422390.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    41. Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. PLoS One. 2014; 9(8):e103884. Sellier C, Hwang VJ, Dandekar R, Durbin-Johnson B, Charlet-Berguerand N, Ander BP, Sharp FR, Angkustsiri K, Simon TJ, Tassone F. PMID: 25084529; PMCID: PMC4118991.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    42. Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic. PLoS One. 2014; 9(7):e102550. Stamova B, Jickling GC, Ander BP, Zhan X, Liu D, Turner R, Ho C, Khoury JC, Bushnell C, Pancioli A, Jauch EC, Broderick JP, Sharp FR. PMID: 25036109; PMCID: PMC4103830.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    43. Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):226-33. Bai Z, Stamova B, Xu H, Ander BP, Wang J, Jickling GC, Zhan X, Liu D, Han G, Jin LW, DeCarli C, Lei H, Sharp FR. PMID: 24731980; PMCID: PMC4139468.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    44. microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. PLoS One. 2014; 9(6):e99283. Jickling GC, Ander BP, Zhan X, Noblett D, Stamova B, Liu D. PMID: 24911610; PMCID: PMC4050059.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    45. Inhibition of SRC family kinases protects hippocampal neurons and improves cognitive function after traumatic brain injury. J Neurotrauma. 2014 Jul 15; 31(14):1268-76. Liu DZ, Sharp FR, Van KC, Ander BP, Ghiasvand R, Zhan X, Stamova B, Jickling GC, Lyeth BG. PMID: 24428562; PMCID: PMC4108941.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    46. Myelin injury and degraded myelin vesicles in Alzheimer's disease. Curr Alzheimer Res. 2014 Mar; 11(3):232-8. Zhan X, Jickling GC, Ander BP, Liu D, Stamova B, Cox C, Jin LW, DeCarli C, Sharp FR. PMID: 24484278; PMCID: PMC4066812.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    47. Blood Genomics After Brain Ischemia, Hemorrhage, and Trauma. . 2014 Jan 1; 445-457. Liu LD, Jickling JG, Stamova SB, Zhan ZX, Ander AB, Sharp SF. .
      View in: Publisher Site   Mentions:
    48. Hemorrhagic transformation after ischemic stroke in animals and humans. J Cereb Blood Flow Metab. 2014 Feb; 34(2):185-99. Jickling GC, Liu D, Stamova B, Ander BP, Zhan X, Lu A, Sharp FR. PMID: 24281743; PMCID: PMC3915212.
      View in: PubMed   Mentions: 233     Fields:    Translation:HumansAnimalsCells
    49. Autophagy in the brain of neonates following hypoxia-ischemia shows sex- and region-specific effects. Neuroscience. 2014 Jan 03; 256:201-9. Weis SN, Toniazzo AP, Ander BP, Zhan X, Careaga M, Ashwood P, Wyse AT, Netto CA, Sharp FR. PMID: 24184979.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    50. RNA in blood is altered prior to hemorrhagic transformation in ischemic stroke. Ann Neurol. 2013 Aug; 74(2):232-40. Jickling GC, Ander BP, Stamova B, Zhan X, Liu D, Rothstein L, Verro P, Khoury J, Jauch EC, Pancioli AM, Broderick JP, Sharp FR. PMID: 23468366; PMCID: PMC3752310.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    51. An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways. PLoS One. 2013; 8(7):e67672. Peng B, Zhu D, Ander BP, Zhang X, Xue F, Sharp FR, Yang X. PMID: 23844055; PMCID: PMC3700986.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    52. Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study. J Neuroimmunol. 2013 Apr 15; 257(1-2):90-6. Apperson ML, Tian Y, Stamova B, Ander BP, Jickling GC, Agius MA, Sharp FR. PMID: 23477965.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    53. Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study. BMC Med Genomics. 2012 Oct 30; 5:49. Tian Y, Stamova B, Ander BP, Jickling GC, Gunther JR, Corbett BA, Bos-Veneman NG, Hoekstra PJ, Schweitzer JB, Sharp FR. PMID: 23110997; PMCID: PMC3497583.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    54. Catecholamine-related gene expression in blood correlates with tic severity in tourette syndrome. Psychiatry Res. 2012 Dec 30; 200(2-3):593-601. Gunther J, Tian Y, Stamova B, Lit L, Corbett B, Ander B, Zhan X, Jickling G, Bos-Veneman N, Liu D, Hoekstra P, Sharp F. PMID: 22648010.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    55. Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location. Stroke. 2012 Aug; 43(8):2036-41. Jickling GC, Stamova B, Ander BP, Zhan X, Liu D, Sison SM, Verro P, Sharp FR. PMID: 22627989; PMCID: PMC3422649.
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    56. Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update. ScientificWorldJournal. 2012; 2012:491737. Liu DZ, Ander BP. PMID: 22547985; PMCID: PMC3323905.
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    57. Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls. Gend Med. 2012 Apr; 9(2):68-75.e3. Tian Y, Stamova B, Jickling GC, Xu H, Liu D, Ander BP, Bushnell C, Zhan X, Turner RJ, Davis RR, Verro P, Pevec WC, Hedayati N, Dawson DL, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp FR. PMID: 22365286; PMCID: PMC3454519.
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    58. Ischemic transient neurological events identified by immune response to cerebral ischemia. Stroke. 2012 Apr; 43(4):1006-12. Jickling GC, Zhan X, Stamova B, Ander BP, Tian Y, Liu D, Sison SM, Verro P, Johnston SC, Sharp FR. PMID: 22308247; PMCID: PMC3327404.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    59. Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells. Gene. 2012 Mar 10; 495(2):120-7. Liu DZ, Ander BP, Tian Y, Stamova B, Jickling GC, Davis RR, Sharp FR. PMID: 22244746.
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    60. Effects of gender on gene expression in the blood of ischemic stroke patients. J Cereb Blood Flow Metab. 2012 May; 32(5):780-91. Tian Y, Stamova B, Jickling GC, Liu D, Ander BP, Bushnell C, Zhan X, Davis RR, Verro P, Pevec WC, Hedayati N, Dawson DL, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp FR. PMID: 22167233; PMCID: PMC3345909.
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    61. Gene expression profiling of blood in brain arteriovenous malformation patients. Transl Stroke Res. 2011 Dec 01; 2(4):575-87. Weinsheimer SM, Xu H, Achrol AS, Stamova B, McCulloch CE, Pawlikowska L, Tian Y, Ko NU, Lawton MT, Steinberg GK, Chang SD, Jickling G, Ander BP, Kim H, Sharp FR, Young WL. PMID: 22184505; PMCID: PMC3241209.
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    62. The X-chromosome has a different pattern of gene expression in women compared with men with ischemic stroke. Stroke. 2012 Feb; 43(2):326-34. Stamova B, Tian Y, Jickling G, Bushnell C, Zhan X, Liu D, Ander BP, Verro P, Patel V, Pevec WC, Hedayati N, Dawson DL, Jauch EC, Pancioli A, Broderick JP, Sharp FR. PMID: 22052522; PMCID: PMC3938328.
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    63. The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression. Lipids. 2011 Nov; 46(11):1043-52. McCullough RS, Edel AL, Bassett CM, Lavallée RK, Dibrov E, Blackwood DP, Ander BP, Pierce GN. PMID: 22031167; PMCID: PMC3213345.
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    64. Transient ischemic attacks characterized by RNA profiles in blood. Neurology. 2011 Nov 08; 77(19):1718-24. Zhan X, Jickling GC, Tian Y, Stamova B, Xu H, Ander BP, Turner RJ, Mesias M, Verro P, Bushnell C, Johnston SC, Sharp FR. PMID: 21998319; PMCID: PMC3208953.
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    65. Profiles of lacunar and nonlacunar stroke. Ann Neurol. 2011 Sep; 70(3):477-85. Jickling GC, Stamova B, Ander BP, Zhan X, Tian Y, Liu D, Xu H, Johnston SC, Verro P, Sharp FR. PMID: 21796664; PMCID: PMC3201749.
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    66. Gene expression in blood is associated with risperidone response in children with autism spectrum disorders. Pharmacogenomics J. 2012 Oct; 12(5):368-71. Lit L, Sharp FR, Bertoglio K, Stamova B, Ander BP, Sossong AD, Hendren RL. PMID: 21647175; PMCID: PMC3175502.
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    67. RNA expression profiles from blood for the diagnosis of stroke and its causes. J Child Neurol. 2011 Sep; 26(9):1131-6. Sharp FR, Jickling GC, Stamova B, Tian Y, Zhan X, Ander BP, Cox C, Kuczynski B, Liu D. PMID: 21636778; PMCID: PMC3674558.
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    68. Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humans. J Cereb Blood Flow Metab. 2011 Jul; 31(7):1513-31. Sharp FR, Jickling GC, Stamova B, Tian Y, Zhan X, Liu D, Kuczynski B, Cox CD, Ander BP. PMID: 21505474; PMCID: PMC3137473.
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    69. GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study. Brain Res. 2011 Mar 24; 1381:228-36. Tian Y, Gunther JR, Liao IH, Liu D, Ander BP, Stamova BS, Lit L, Jickling GC, Xu H, Zhan X, Sharp FR. PMID: 21241679.
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    70. Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjects. J Neuroimmunol. 2011 Jan; 230(1-2):124-9. Tian Y, Apperson ML, Ander BP, Liu D, Stomova BS, Jickling GC, Enriquez R, Agius MA, Sharp FR. PMID: 20920832.
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    71. Exon expression and alternatively spliced genes in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan; 156B(1):72-8. Tian Y, Liao IH, Zhan X, Gunther JR, Ander BP, Liu D, Lit L, Jickling GC, Corbett BA, Bos-Veneman NG, Hoekstra PJ, Sharp FR. PMID: 21184586; PMCID: PMC3070201.
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    72. Signatures of cardioembolic and large-vessel ischemic stroke. Ann Neurol. 2010 Nov; 68(5):681-92. Jickling GC, Xu H, Stamova B, Ander BP, Zhan X, Tian Y, Liu D, Turner RJ, Mesias M, Verro P, Khoury J, Jauch EC, Pancioli A, Broderick JP, Sharp FR. PMID: 21031583; PMCID: PMC2967466.
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    73. Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. Stroke. 2010 Dec; 41(12):2744-9. Xu H, Stamova B, Jickling G, Tian Y, Zhan X, Ander BP, Liu D, Turner R, Rosand J, Goldstein LB, Furie KL, Verro P, Johnston SC, Sharp FR, Decarli CS. PMID: 20966416; PMCID: PMC3694808.
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    74. Gene expression profiling of blood for the prediction of ischemic stroke. Stroke. 2010 Oct; 41(10):2171-7. Stamova B, Xu H, Jickling G, Bushnell C, Tian Y, Ander BP, Zhan X, Liu D, Turner R, Adamczyk P, Khoury JC, Pancioli A, Jauch E, Broderick JP, Sharp FR. PMID: 20798371; PMCID: PMC2987675.
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    75. Genome response to tissue plasminogen activator in experimental ischemic stroke. BMC Genomics. 2010 Apr 21; 11:254. Jickling GC, Zhan X, Ander BP, Turner RJ, Stamova B, Xu H, Tian Y, Liu D, Davis RR, Lapchak PA, Sharp FR. PMID: 20406488; PMCID: PMC2875237.
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    76. Blood-brain barrier breakdown and repair by Src after thrombin-induced injury. Ann Neurol. 2010 Apr; 67(4):526-33. Liu DZ, Ander BP, Xu H, Shen Y, Kaur P, Deng W, Sharp FR. PMID: 20437588; PMCID: PMC2919346.
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    77. Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats. Stroke. 2010 Mar; 41(3):538-43. Zhan X, Ander BP, Liao IH, Hansen JE, Kim C, Clements D, Weisbart RH, Nishimura RN, Sharp FR. PMID: 20075343; PMCID: PMC2957177.
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    78. Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of central nervous system diseases. Neurobiol Dis. 2010 Mar; 37(3):549-57. Liu DZ, Ander BP, Sharp FR. PMID: 19944161; PMCID: PMC2823995.
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    79. Distribution of omega-3 fatty acids in tissues of rabbits fed a flaxseed-supplemented diet. Metabolism. 2010 May; 59(5):620-7. Ander BP, Edel AL, McCullough R, Rodriguez-Leyva D, Rampersad P, Gilchrist JS, Lukas A, Pierce GN. PMID: 19913851.
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    80. WITHDRAWN: Cell cycle Inhibition as a Strategy for Treatment of Central Nervous System Diseases. Recent Pat Nanotechnol. 2009 Nov 01. Liu DZ, Ander BP, Sharp FR. PMID: 19534699.
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    81. Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood. J Cereb Blood Flow Metab. 2010 Jan; 30(1):110-8. Zhan X, Ander BP, Jickling G, Turner R, Stamova B, Xu H, Liu D, Davis RR, Sharp FR. PMID: 19738631; PMCID: PMC2949112.
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    82. Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J Cereb Blood Flow Metab. 2010 Jan; 30(1):92-101. Liu DZ, Tian Y, Ander BP, Xu H, Stamova BS, Zhan X, Turner RJ, Jickling G, Sharp FR. PMID: 19724284; PMCID: PMC2949089.
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    83. Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood. BMC Med Genomics. 2009 Aug 05; 2:49. Stamova BS, Apperson M, Walker WL, Tian Y, Xu H, Adamczy P, Zhan X, Liu DZ, Ander BP, Liao IH, Gregg JP, Turner RJ, Jickling G, Lit L, Sharp FR. PMID: 19656400; PMCID: PMC2736983.
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    84. Corticosteroid effects on blood gene expression in Duchenne muscular dystrophy. Pharmacogenomics J. 2009 Dec; 9(6):411-8. Lit L, Sharp FR, Apperson M, Liu DZ, Walker WL, Liao I, Xu H, Ander BP, Wong B. PMID: 19488064.
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    85. Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke. J Cereb Blood Flow Metab. 2008 Jul; 28(7):1320-8. Xu H, Tang Y, Liu DZ, Ran R, Ander BP, Apperson M, Liu XS, Khoury JC, Gregg JP, Pancioli A, Jauch EC, Wagner KR, Verro P, Broderick JP, Sharp FR. PMID: 18382470.
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    86. Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet. Can J Physiol Pharmacol. 2008 Apr; 86(4):153-9. Prociuk MA, Edel AL, Richard MN, Gavel NT, Ander BP, Dupasquier CM, Pierce GN. PMID: 18418423.
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    87. Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons. Neurobiol Dis. 2008 May; 30(2):201-11. Liu DZ, Cheng XY, Ander BP, Xu H, Davis RR, Gregg JP, Sharp FR. PMID: 18343677; PMCID: PMC2413433.
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    88. Intracerebral hemorrhage injury mechanisms: glutamate neurotoxicity, thrombin, and Src. Acta Neurochir Suppl. 2008; 105:43-6. Sharp F, Liu DZ, Zhan X, Ander BP. PMID: 19066080.
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    89. SRC kinase inhibition improves acute outcomes after experimental intracerebral hemorrhage. Stroke. 2007 May; 38(5):1621-5. Ardizzone TD, Zhan X, Ander BP, Sharp FR. PMID: 17395859.
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    90. Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury. Am J Physiol Regul Integr Comp Physiol. 2007 Mar; 292(3):R1198-203. Al-Khalifa A, Maddaford TG, Chahine MN, Austria JA, Edel AL, Richard MN, Ander BP, Gavel N, Kopilas M, Ganguly R, Ganguly PK, Pierce GN. PMID: 17122327.
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    91. Differential sensitivities of the NCX1.1 and NCX1.3 isoforms of the Na+-Ca2+ exchanger to alpha-linolenic acid. Cardiovasc Res. 2007 Jan 15; 73(2):395-403. Ander BP, Hurtado C, Raposo CS, Maddaford TG, Deniset JF, Hryshko LV, Pierce GN, Lukas A. PMID: 17059813.
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    92. Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2987-96. Dupasquier CM, Weber AM, Ander BP, Rampersad PP, Steigerwald S, Wigle JT, Mitchell RW, Kroeger EA, Gilchrist JS, Moghadasian MM, Lukas A, Pierce GN. PMID: 16844912.
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    93. The effects of dietary hempseed on cardiac ischemia/reperfusion injury in hypercholesterolemic rabbits. Exp Clin Cardiol. 2006; 11(3):198-205. Prociuk M, Edel A, Gavel N, Deniset J, Ganguly R, Austria J, Ander B, Lukas A, Pierce G. PMID: 18651032; PMCID: PMC2276149.
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    94. Adenovirally delivered shRNA strongly inhibits Na+-Ca2+ exchanger expression but does not prevent contraction of neonatal cardiomyocytes. J Mol Cell Cardiol. 2005 Apr; 38(4):647-54. Hurtado C, Ander BP, Maddaford TG, Lukas A, Hryshko LV, Pierce GN. PMID: 15808841.
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    95. Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic Rabbits. J Nutr. 2004 Dec; 134(12):3250-6. Ander BP, Weber AR, Rampersad PP, Gilchrist JS, Pierce GN, Lukas A. PMID: 15570021.
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    96. Polyunsaturated fatty acids and their effects on cardiovascular disease. Exp Clin Cardiol. 2003; 8(4):164-72. Ander BP, Dupasquier CM, Prociuk MA, Pierce GN. PMID: 19649216; PMCID: PMC2719153.
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