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Tony J Simon, PhD

Title(s)Professor, Psychiatry and Behavioral Sciences
SchoolUniversity of California, Davis
AddressMIND Institute/UCDMC
CA 95817
Phone916-703-0407
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    Collapse Research 
    Collapse Research Activities and Funding
    Cognitive-Affective Psychosis Proneness Risk and protective factors in 22q11.2DS
    NIH/NIMH R01MH107108Aug 1, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Fragile X Spectrum as Model for Neurogenetic Mechanisms of Cognitive Dysfunction
    NIH/NINDS RL1NS062412Sep 30, 2007 - Jun 30, 2013
    Role: Principal Investigator
    Numerical Deficits Across Multiple Genetic Disorders
    NIH/NICHD R01HD046159Sep 25, 2003 - Jul 31, 2010
    Role: Principal Investigator
    Visuospatial Cognitive Deficit in Del22q11.2 Syndrome
    NIH/NICHD R01HD042974Apr 1, 2003 - Jul 31, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Adaptive functioning in children and adolescents with Trisomy X: An exploratory analysis. Am J Med Genet C Semin Med Genet. 2020 06; 184(2):456-468. Wigby K, Cordeiro L, Wilson R, Angkustsiri K, Simon TJ, Tartaglia N. PMID: 32548885.
      View in: PubMed   Mentions: 1     Fields:    
    2. Replication of Associations With Psychotic-Like Experiences in Middle Childhood From the Adolescent Brain Cognitive Development (ABCD) Study. Schizophr Bull Open. 2020 Jan; 1(1):sgaa009. Karcher NR, Loewy RL, Savill M, Avenevoli S, Huber RS, Simon TJ, Leckliter IN, Sher KJ, Barch DM. PMID: 32803159.
      View in: PubMed   Mentions:
    3. Neural and behavioral measures suggest that cognitive and affective functioning interactions mediate risk for psychosis-proneness symptoms in youth with chromosome 22q11.2 deletion syndrome. Am J Med Genet A. 2020 07; 182(7):1615-1630. Linton SR, Popa AM, Luck SJ, Bolden K, Carter CS, Niendam TA, Simon TJ. PMID: 32319730.
      View in: PubMed   Mentions:
    4. Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness. Am J Psychiatry. 2020 07 01; 177(7):589-600. Ching CRK, Gutman BA, Sun D, Villalon Reina J, Ragothaman A, Isaev D, Zavaliangos-Petropulu A, Lin A, Jonas RK, Kushan L, Pacheco-Hansen L, Vajdi A, Forsyth JK, Jalbrzikowski M, Bakker G, van Amelsvoort T, Antshel KM, Fremont W, Kates WR, Campbell LE, McCabe KL, Craig MC, Daly E, Gudbrandsen M, Murphy CM, Murphy DG, Murphy KC, Fiksinski A, Koops S, Vorstman J, Crowley TB, Emanuel BS, Gur RE, McDonald-McGinn DM, Roalf DR, Ruparel K, Schmitt JE, Zackai EH, Durdle CA, Goodrich-Hunsaker NJ, Simon TJ, Bassett AS, Butcher NJ, Chow EWC, Vila-Rodriguez F, Cunningham A, Doherty J, Linden DE, Moss H, Owen MJ, van den Bree M, Crossley NA, Repetto GM, Thompson PM, Bearden CE. PMID: 32046535.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion. Mol Psychiatry. 2020 Feb 03. Cleynen I, Engchuan W, Hestand MS, Heung T, Holleman AM, Johnston HR, Monfeuga T, McDonald-McGinn DM, Gur RE, Morrow BE, Swillen A, Vorstman JAS, Bearden CE, Chow EWC, van den Bree M, Emanuel BS, Vermeesch JR, Warren ST, Owen MJ, Chopra P, Cutler DJ, Duncan R, Kotlar AV, Mulle JG, Voss AJ, Zwick ME, Diacou A, Golden A, Guo T, Lin JR, Wang T, Zhang Z, Zhao Y, Marshall C, Merico D, Jin A, Lilley B, Salmons HI, Tran O, Holmans P, Pardinas A, Walters JTR, Demaerel W, Boot E, Butcher NJ, Costain GA, Lowther C, Evers R, van Amelsvoort TAMJ, van Duin E, Vingerhoets C, Breckpot J, Devriendt K, Vergaelen E, Vogels A, Crowley TB, McGinn DE, Moss EM, Sharkus RJ, Unolt M, Zackai EH, Calkins ME, Gallagher RS, Gur RC, Tang SX, Fritsch R, Ornstein C, Repetto GM, Breetvelt E, Duijff SN, Fiksinski A, Moss H, Niarchou M, Murphy KC, Prasad SE, Daly EM, Gudbrandsen M, Murphy CM, Murphy DG, Buzzanca A, Fabio FD, Digilio MC, Pontillo M, Marino B, Vicari S, Coleman K, Cubells JF, Ousley OY, Carmel M, Gothelf D, Mekori-Domachevsky E, Michaelovsky E, Weinberger R, Weizman A, Kushan L, Jalbrzikowski M, Armando M, Eliez S, Sandini C, Schneider M, Béna FS, Antshel KM, Fremont W, Kates WR, Belzeaux R, Busa T, Philip N, Campbell LE, McCabe KL, Hooper SR, Schoch K, Shashi V, Simon TJ, Tassone F, Arango C, Fraguas D, García-Miñaúr S, Morey-Canyelles J, Rosell J, Suñer DH, Raventos-Simic J, Epstein MP, Williams NM, Bassett AS. PMID: 32015465.
      View in: PubMed   Mentions: 2     Fields:    
    6. Quantifying the resolution of spatial and temporal representation in children with 22q11.2 deletion syndrome. J Neurodev Disord. 2019 12 20; 11(1):40. McCabe KL, Popa AM, Durdle C, Amato M, Cabaral MH, Cruz J, Wong LM, Harvey D, Tartaglia N, Simon TJ. PMID: 31861974.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects. Am J Hum Genet. 2020 01 02; 106(1):26-40. Zhao Y, Diacou A, Johnston HR, Musfee FI, McDonald-McGinn DM, McGinn D, Crowley TB, Repetto GM, Swillen A, Breckpot J, Vermeesch JR, Kates WR, Digilio MC, Unolt M, Marino B, Pontillo M, Armando M, Di Fabio F, Vicari S, van den Bree M, Moss H, Owen MJ, Murphy KC, Murphy CM, Murphy D, Schoch K, Shashi V, Tassone F, Simon TJ, Shprintzen RJ, Campbell L, Philip N, Heine-Suñer D, García-Miñaúr S, Fernández L, Bearden CE, Vingerhoets C, van Amelsvoort T, Eliez S, Schneider M, Vorstman JAS, Gothelf D, Zackai E, Agopian AJ, Gur RE, Bassett AS, Emanuel BS, Goldmuntz E, Mitchell LE, Wang T, Morrow BE. PMID: 31870554.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Seeing Eye to Eye With Threat: Atypical Threat Bias in Children With 22q11.2 Deletion Syndrome. Am J Intellect Dev Disabil. 2019 11; 124(6):549-567. Popa AM, Cruz JR, Wong LM, Harvey DJ, Angkustsiri K, Leckliter IN, Perez-Edgar K, Simon TJ. PMID: 31756146.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Interrelationship Between Cognitive Control, Anxiety, and Restricted and Repetitive Behaviors in Children with 22q11.2 Deletion Syndrome. Autism Res. 2019 12; 12(12):1737-1744. Uljarevic M, McCabe KL, Angkustsiri K, Simon TJ, Hardan AY. PMID: 31433576.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study. Mol Psychiatry. 2019 Jul 29. Villalón-Reina JE, Martínez K, Qu X, Ching CRK, Nir TM, Kothapalli D, Corbin C, Sun D, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL, Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Emanuel B, McDonald-McGinn DM, Vorstman JAS, Fiksinski AM, Koops S, Ruparel K, Roalf D, Gur RE, Eric Schmitt J, Simon TJ, Goodrich-Hunsaker NJ, Durdle CA, Doherty JL, Cunningham AC, van den Bree M, Linden DEJ, Owen M, Moss H, Kelly S, Donohoe G, Murphy KC, Arango C, Jahanshad N, Thompson PM, Bearden CE. PMID: 31358905.
      View in: PubMed   Mentions: 4     Fields:    
    11. Bullying and psychosis: The impact of chronic traumatic stress on psychosis risk in 22q11.2 deletion syndrome - a uniquely vulnerable population. J Psychiatr Res. 2019 07; 114:99-104. Mayo D, Bolden KA, Simon TJ, Niendam TA. PMID: 31054456.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Alternative diffusion anisotropy measures for the investigation of white matter alterations in 22q11.2 deletion syndrome. . 2018 Dec 21; 10975:109750u. Julio E. Villalon-Reina, Christopher R. K. Ching, Deydeep Kothapalli, Daqiang Sun, Talia Nir, Amy Lin, Jennifer K. Forsyth, Leila Kushan, Ariana Vajdi, Maria Jalbrzikowski, Laura Hansen, Rachel K. Jonas, Therese van Amelsvoort, Geor Bakker, Wendy R. Kates, Kevin M. Antshel, Wanda Fremont, Linda E. Campbell, Kathryn L. McCabe, Eileen Daly, Maria Gudbrandsen, Clodagh Murphy, Declan Murphy, Michael Craig, Beverly Emanuel, Donna McDonald-McGinn, Kosha Ruparel, David Roalf, Raquel E. Gur, J. Eric Schmitt, Tony J. Simon, Naomi J. Goodrich-Hunsaker, Courtney A. Durdle, Joanne Doherty, Adam C. Cunningham, Marianne van den Bree, David E.J. Linden, Michael Owen, Hayley Moss, Neda Jahanshad, Carrie E. Bearden, Paul M. Thompson. .
      View in: Publisher Site   Mentions:
    13. Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. Am J Med Genet A. 2018 10; 176(10):2172-2181. Zhao Y, Guo T, Fiksinski A, Breetvelt E, McDonald-McGinn DM, Crowley TB, Diacou A, Schneider M, Eliez S, Swillen A, Breckpot J, Vermeesch J, Chow EWC, Gothelf D, Duijff S, Evers R, van Amelsvoort TA, van den Bree M, Owen M, Niarchou M, Bearden CE, Ornstein C, Pontillo M, Buzzanca A, Vicari S, Armando M, Murphy KC, Murphy C, Garcia-Minaur S, Philip N, Campbell L, Morey-Cañellas J, Raventos J, Rosell J, Heine-Suner D, Shprintzen RJ, Gur RE, Zackai E, Emanuel BS, Wang T, Kates WR, Bassett AS, Vorstman JAS, Morrow BE. PMID: 30289625.
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    14. Retraction Notice to: Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements. Am J Hum Genet. 2018 09 06; 103(3):457. Demaerel W, Hestand MS, Vergaelen E, Swillen A, López-Sánchez M, Pérez-Jurado LA, McDonald-McGinn DM, Zackai E, Emanuel BS, Morrow BE, Breckpot J, Devriendt K, Vermeesch JR. PMID: 30193139.
      View in: PubMed   Mentions:    Fields:    
    15. Assessment of the Prodromal Questionnaire-Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood. JAMA Psychiatry. 2018 08 01; 75(8):853-861. Karcher NR, Barch DM, Avenevoli S, Savill M, Huber RS, Simon TJ, Leckliter IN, Sher KJ, Loewy RL. PMID: 29874361.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    16. Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size. Mol Psychiatry. 2020 Aug; 25(8):1822-1834. Sun D, Ching CRK, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Villalon-Reina JE, Qu X, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL, Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Vorstman J, Fiksinski A, Koops S, Ruparel K, Roalf DR, Gur RE, Schmitt JE, Simon TJ, Goodrich-Hunsaker NJ, Durdle CA, Bassett AS, Chow EWC, Butcher NJ, Vila-Rodriguez F, Doherty J, Cunningham A, van den Bree MBM, Linden DEJ, Moss H, Owen MJ, Murphy KC, McDonald-McGinn DM, Emanuel B, van Erp TGM, Turner JA, Thompson PM, Bearden CE. PMID: 29895892.
      View in: PubMed   Mentions: 15     Fields:    
    17. A higher rare CNV burden in the genetic background potentially contributes to intellectual disability phenotypes in 22q11.2 deletion syndrome. Eur J Med Genet. 2018 Apr; 61(4):209-212. Jensen M, Kooy RF, Simon TJ, Reyniers E, Girirajan S, Tassone F. PMID: 29191496.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Baseline connectome modular abnormalities in the childhood phase of a longitudinal study on individuals with chromosome 22q11.2 deletion syndrome. Hum Brain Mapp. 2018 01; 39(1):232-248. Zhan L, Jenkins LM, Zhang A, Conte G, Forbes A, Harvey D, Angkustsiri K, Goodrich-Hunsaker NJ, Durdle C, Lee A, Schumann C, Carmichael O, Kalish K, Leow AD, Simon TJ. PMID: 28990258.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3. Circ Cardiovasc Genet. 2017 Oct; 10(5). Guo T, Repetto GM, McDonald McGinn DM, Chung JH, Nomaru H, Campbell CL, Blonska A, Bassett AS, Chow EWC, Mlynarski EE, Swillen A, Vermeesch J, Devriendt K, Gothelf D, Carmel M, Michaelovsky E, Schneider M, Eliez S, Antonarakis SE, Coleman K, Tomita-Mitchell A, Mitchell ME, Digilio MC, Dallapiccola B, Marino B, Philip N, Busa T, Kushan-Wells L, Bearden CE, Piotrowicz M, Hawula W, Roberts AE, Tassone F, Simon TJ, van Duin EDA, van Amelsvoort TA, Kates WR, Zackai E, Johnston HR, Cutler DJ, Agopian AJ, Goldmuntz E, Mitchell LE, Wang T, Emanuel BS, Morrow BE. PMID: 29025761.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    20. Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements. Am J Hum Genet. 2017 Oct 05; 101(4):616-622. Demaerel W, Hestand MS, Vergaelen E, Swillen A, López-Sánchez M, Pérez-Jurado LA, McDonald-McGinn DM, Zackai E, Emanuel BS, Morrow BE, Breckpot J, Devriendt K, Vermeesch JR. PMID: 28965848.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Subthreshold Psychosis in 22q11.2 Deletion Syndrome: Multisite Naturalistic Study. Schizophr Bull. 2017 09 01; 43(5):1079-1089. Weisman O, Guri Y, Gur RE, McDonald-McGinn DM, Calkins ME, Tang SX, Emanuel B, Zackai EH, Eliez S, Schneider M, Schaer M, Kates WR, Antshel KM, Fremont W, Shashi V, Hooper SR, Armando M, Vicari S, Pontillo M, Kushan L, Jalbrzikowski M, Bearden CE, Cubells JF, Ousley OY, Walker EF, Simon TJ, Stoddard J, Niendam TA, van den Bree MBM, Gothelf D. PMID: 28204757.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Rare Genome-Wide Copy Number Variation and Expression of Schizophrenia in 22q11.2 Deletion Syndrome. Am J Psychiatry. 2017 11 01; 174(11):1054-1063. Bassett AS, Lowther C, Merico D, Costain G, Chow EWC, van Amelsvoort T, McDonald-McGinn D, Gur RE, Swillen A, Van den Bree M, Murphy K, Gothelf D, Bearden CE, Eliez S, Kates W, Philip N, Sashi V, Campbell L, Vorstman J, Cubells J, Repetto GM, Simon T, Boot E, Heung T, Evers R, Vingerhoets C, van Duin E, Zackai E, Vergaelen E, Devriendt K, Vermeesch JR, Owen M, Murphy C, Michaelovosky E, Kushan L, Schneider M, Fremont W, Busa T, Hooper S, McCabe K, Duijff S, Isaev K, Pellecchia G, Wei J, Gazzellone MJ, Scherer SW, Emanuel BS, Guo T, Morrow BE, Marshall CR. PMID: 28750581.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    23. Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation. Neurobiol Aging. 2017 07; 55:11-19. Wang JY, Hessl D, Hagerman RJ, Simon TJ, Tassone F, Ferrer E, Rivera SM. PMID: 28391068.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    24. The hippocampi of children with chromosome 22q11.2 deletion syndrome have localized anterior alterations that predict severity of anxiety. J Psychiatry Neurosci. 2016 04; 41(3):203-13. Scott JA, Goodrich-Hunsaker N, Kalish K, Lee A, Hunsaker MR, Schumann CM, Carmichael OT, Simon TJ. PMID: 26599134.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Rare copy number variants and congenital heart defects in the 22q11.2 deletion syndrome. Hum Genet. 2016 Mar; 135(3):273-85. Mlynarski EE, Xie M, Taylor D, Sheridan MB, Guo T, Racedo SE, McDonald-McGinn DM, Chow EW, Vorstman J, Swillen A, Devriendt K, Breckpot J, Digilio MC, Marino B, Dallapiccola B, Philip N, Simon TJ, Roberts AE, Piotrowicz M, Bearden CE, Eliez S, Gothelf D, Coleman K, Kates WR, Devoto M, Zackai E, Heine-Suñer D, Goldmuntz E, Bassett AS, Morrow BE, Emanuel BS. PMID: 26742502.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    26. Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion Syndrome. J Biol Chem. 2015 Sep 18; 290(38):23240-53. Napoli E, Tassone F, Wong S, Angkustsiri K, Simon TJ, Song G, Giulivi C. PMID: 26221035.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    27. Erratum: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder. Mol Autism. 2015; 6:39. Nordahl CW, Iosif AM, Young GS, Perry LM, Dougherty R, Lee A, Li D, Buonocore MH, Simon T, Rogers S, Wandell B, Amaral DG. PMID: 26097676.
      View in: PubMed   Mentions:    Fields:    
    28. Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder. Mol Autism. 2015; 6:26. Nordahl CW, Iosif AM, Young GS, Perry LM, Dougherty R, Lee A, Li D, Buonocore MH, Simon T, Rogers S, Wandell B, Amaral DG. PMID: 25973163.
      View in: PubMed   Mentions: 20     Fields:    
    29. Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome. Am J Hum Genet. 2015 May 07; 96(5):753-64. Mlynarski EE, Sheridan MB, Xie M, Guo T, Racedo SE, McDonald-McGinn DM, Gai X, Chow EW, Vorstman J, Swillen A, Devriendt K, Breckpot J, Digilio MC, Marino B, Dallapiccola B, Philip N, Simon TJ, Roberts AE, Piotrowicz M, Bearden CE, Eliez S, Gothelf D, Coleman K, Kates WR, Devoto M, Zackai E, Heine-Suñer D, Shaikh TH, Bassett AS, Goldmuntz E, Morrow BE, Emanuel BS. PMID: 25892112.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    30. Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome. JAMA Psychiatry. 2015 Apr; 72(4):377-85. Vorstman JA, Breetvelt EJ, Duijff SN, Eliez S, Schneider M, Jalbrzikowski M, Armando M, Vicari S, Shashi V, Hooper SR, Chow EW, Fung WL, Butcher NJ, Young DA, McDonald-McGinn DM, Vogels A, van Amelsvoort T, Gothelf D, Weinberger R, Weizman A, Klaassen PW, Koops S, Kates WR, Antshel KM, Simon TJ, Ousley OY, Swillen A, Gur RE, Bearden CE, Kahn RS, Bassett AS. PMID: 25715178.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    31. Disrupted fornix integrity in children with chromosome 22q11.2 deletion syndrome. Psychiatry Res. 2015 Apr 30; 232(1):106-14. Deng Y, Goodrich-Hunsaker NJ, Cabaral M, Amaral DG, Buonocore MH, Harvey D, Kalish K, Carmichael OT, Schumann CM, Lee A, Dougherty RF, Perry LM, Wandell BA, Simon TJ. PMID: 25748884.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Temporal dynamics of attentional selection in adult male carriers of the fragile X premutation allele and adult controls. Front Hum Neurosci. 2015; 9:37. Wong LM, Tassone F, Rivera SM, Simon TJ. PMID: 25698960.
      View in: PubMed   Mentions:
    33. A cross-sectional analysis of orienting of visuospatial attention in child and adult carriers of the fragile X premutation. J Neurodev Disord. 2014; 6(1):45. Wong LM, Goodrich-Hunsaker NJ, McLennan YA, Tassone F, Rivera SM, Simon TJ. PMID: 25937844.
      View in: PubMed   Mentions:    Fields:    
    34. Mapping the deletion endpoints in individuals with 22q11.2 deletion syndrome by droplet digital PCR. BMC Med Genet. 2014 Oct 14; 15:106. Hwang VJ, Maar D, Regan J, Angkustsiri K, Simon TJ, Tassone F. PMID: 25312060.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. PLoS One. 2014; 9(8):e103884. Sellier C, Hwang VJ, Dandekar R, Durbin-Johnson B, Charlet-Berguerand N, Ander BP, Sharp FR, Angkustsiri K, Simon TJ, Tassone F. PMID: 25084529.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    36. The development of cognitive control in children with chromosome 22q11.2 deletion syndrome. Front Psychol. 2014; 5:566. Shapiro HM, Tassone F, Choudhary NS, Simon TJ. PMID: 24959159.
      View in: PubMed   Mentions:
    37. Identifying patterns of anxiety and depression in children with chromosome 22q11.2 deletion syndrome: comorbidity predicts behavioral difficulties and impaired functional communications. Behav Brain Res. 2015 Jan 01; 276:190-8. Stephenson DD, Beaton EA, Weems CF, Angkustsiri K, Simon TJ. PMID: 24906195.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. Am J Psychiatry. 2014 Jun; 171(6):627-39. Schneider M, Debbané M, Bassett AS, Chow EW, Fung WL, van den Bree M, Owen M, Murphy KC, Niarchou M, Kates WR, Antshel KM, Fremont W, McDonald-McGinn DM, Gur RE, Zackai EH, Vorstman J, Duijff SN, Klaassen PW, Swillen A, Gothelf D, Green T, Weizman A, Van Amelsvoort T, Evers L, Boot E, Shashi V, Hooper SR, Bearden CE, Jalbrzikowski M, Armando M, Vicari S, Murphy DG, Ousley O, Campbell LE, Simon TJ, Eliez S. PMID: 24577245.
      View in: PubMed   Mentions: 181     Fields:    Translation:Humans
    39. Eye movements reveal impaired inhibitory control in adult male fragile X premutation carriers asymptomatic for FXTAS. Neuropsychology. 2014 Jul; 28(4):571-584. Wong LM, Goodrich-Hunsaker NJ, McLennan Y, Tassone F, Zhang M, Rivera SM, Simon TJ. PMID: 24773414.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    40. Social impairments in chromosome 22q11.2 deletion syndrome (22q11.2DS): autism spectrum disorder or a different endophenotype? J Autism Dev Disord. 2014 Apr; 44(4):739-46. Angkustsiri K, Goodlin-Jones B, Deprey L, Brahmbhatt K, Harris S, Simon TJ. PMID: 24045981.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    41. Common and specific impairments in attention functioning in girls with chromosome 22q11.2 deletion, fragile X or Turner syndromes. J Neurodev Disord. 2014 Mar 14; 6(1):5. Quintero AI, Beaton EA, Harvey DJ, Ross JL, Simon TJ. PMID: 24628892.
      View in: PubMed   Mentions: 2     Fields:    
    42. Children with chromosome 22q11.2 deletion syndrome exhibit impaired spatial working memory. Am J Intellect Dev Disabil. 2014 Mar; 119(2):115-32. Wong LM, Riggins T, Harvey D, Cabaral M, Simon TJ. PMID: 24679349.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    43. Altered structural brain connectome in young adult fragile X premutation carriers. Hum Brain Mapp. 2014 Sep; 35(9):4518-30. Leow A, Harvey D, Goodrich-Hunsaker NJ, Gadelkarim J, Kumar A, Zhan L, Rivera SM, Simon TJ. PMID: 24578183.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    44. Altered neural activity in the 'when' pathway during temporal processing in fragile X premutation carriers. Behav Brain Res. 2014 Mar 15; 261:240-8. Kim SY, Tassone F, Simon TJ, Rivera SM. PMID: 24398265.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    45. Altered neural activity of magnitude estimation processing in adults with the fragile X premutation. J Psychiatr Res. 2013 Dec; 47(12):1909-16. Kim SY, Hashimoto R, Tassone F, Simon TJ, Rivera SM. PMID: 24045061.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    46. A cross-sectional analysis of the development of response inhibition in children with chromosome 22q11.2 deletion syndrome. Front Psychiatry. 2013; 4:81. Shapiro HM, Wong LM, Simon TJ. PMID: 23966958.
      View in: PubMed   Mentions:
    47. White matter microstructural abnormalities in girls with chromosome 22q11.2 deletion syndrome, Fragile X or Turner syndrome as evidenced by diffusion tensor imaging. Neuroimage. 2013 Nov 01; 81:441-454. Villalon-Reina J, Jahanshad N, Beaton E, Toga AW, Thompson PM, Simon TJ. PMID: 23602925.
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    48. Young adult male carriers of the fragile X premutation exhibit genetically modulated impairments in visuospatial tasks controlled for psychomotor speed. J Neurodev Disord. 2012 Nov 13; 4(1):26. Wong LM, Goodrich-Hunsaker NJ, McLennan Y, Tassone F, Harvey D, Rivera SM, Simon TJ. PMID: 23148490.
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    49. An examination of the relationship of anxiety and intelligence to adaptive functioning in children with chromosome 22q11.2 deletion syndrome. J Dev Behav Pediatr. 2012 Nov-Dec; 33(9):713-20. Angkustsiri K, Leckliter I, Tartaglia N, Beaton EA, Enriquez J, Simon TJ. PMID: 23117596.
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    50. Overt cleft palate phenotype and TBX1 genotype correlations in velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome patients. . 2012 Nov; 158A(11):2781-7. Herman SB, Guo T, McGinn DM, Blonska A, Shanske AL, Bassett AS, Chow EW, Bowser M, Sheridan M, Beemer F, Devriendt K, Swillen A, Breckpot J, Digilio MC, Marino B, Dallapiccola B, Carpenter C, Zheng X, Johnson J, Chung J, Higgins AM, Philip N, Simon T, Coleman K, Heine-Suner D, Rosell J, Kates W, Devoto M, Zackai E, Wang T, Shprintzen R, Emanuel BS, Morrow BE. PMID: 23034814.
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    51. Impaired multiple object tracking in children with chromosome 22q11.2 deletion syndrome. J Neurodev Disord. 2012 Apr 12; 4(1):6. Cabaral MH, Beaton EA, Stoddard J, Simon TJ. PMID: 22958454.
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    52. A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome. J Neurodev Disord. 2012 Feb 15; 4(1):5. Shapiro HM, Takarae Y, Harvey DJ, Cabaral MH, Simon TJ. PMID: 22958432.
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    53. A second look: no effect of the COMT Val158Met polymorphism on conflict adaptation in youth with chromosome 22q11.2 deletion syndrome. Schizophr Res. 2012 Mar; 135(1-3):202-3. Stoddard J, Takarae Y, Simon TJ. PMID: 22245443.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study. Arch Gen Psychiatry. 2012 Jan; 69(1):53-61. Nordahl CW, Scholz R, Yang X, Buonocore MH, Simon T, Rogers S, Amaral DG. PMID: 22213789.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    55. A framework for quantifying node-level community structure group differences in brain connectivity networks. Med Image Comput Comput Assist Interv. 2012; 15(Pt 2):196-203. GadElkarim JJ, Schonfeld D, Ajilore O, Zhan L, Zhang AF, Feusner JD, Thompson PM, Simon TJ, Kumar A, Leow AD. PMID: 23286049.
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    56. Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50):20195-200. Nordahl CW, Lange N, Li DD, Barnett LA, Lee A, Buonocore MH, Simon TJ, Rogers S, Ozonoff S, Amaral DG. PMID: 22123952.
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    57. Genotype and cardiovascular phenotype correlations with TBX1 in 1,022 velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome patients. Hum Mutat. 2011 Nov; 32(11):1278-89. Guo T, McDonald-McGinn D, Blonska A, Shanske A, Bassett AS, Chow E, Bowser M, Sheridan M, Beemer F, Devriendt K, Swillen A, Breckpot J, Digilio MC, Marino B, Dallapiccola B, Carpenter C, Zheng X, Johnson J, Chung J, Higgins AM, Philip N, Simon TJ, Coleman K, Heine-Suner D, Rosell J, Kates W, Devoto M, Goldmuntz E, Zackai E, Wang T, Shprintzen R, Emanuel B, Morrow B. PMID: 21796729.
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    58. Adult Female Fragile X Premutation Carriers Exhibit Age- and CGG Repeat Length-Related Impairments on an Attentionally Based Enumeration Task. Front Hum Neurosci. 2011; 5:63. Goodrich-Hunsaker NJ, Wong LM, McLennan Y, Tassone F, Harvey D, Rivera SM, Simon TJ. PMID: 21808616.
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    59. Enhanced manual and oral motor reaction time in young adult female fragile X premutation carriers. J Int Neuropsychol Soc. 2011 Jul; 17(4):746-50. Goodrich-Hunsaker NJ, Wong LM, McLennan Y, Tassone F, Harvey D, Rivera SM, Simon TJ. PMID: 21554789.
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    60. Atypical developmental trajectory of functionally significant cortical areas in children with chromosome 22q11.2 deletion syndrome. Hum Brain Mapp. 2012 Jan; 33(1):213-23. Srivastava S, Buonocore MH, Simon TJ. PMID: 21416559.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    61. Young adult female fragile X premutation carriers show age- and genetically-modulated cognitive impairments. Brain Cogn. 2011 Apr; 75(3):255-60. Goodrich-Hunsaker NJ, Wong LM, McLennan Y, Srivastava S, Tassone F, Harvey D, Rivera SM, Simon TJ. PMID: 21295394.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    62. Clues to the foundations of numerical cognitive impairments: evidence from genetic disorders. Dev Neuropsychol. 2011; 36(6):788-805. Simon TJ. PMID: 21761998.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    63. Atypical development of the executive attention network in children with chromosome 22q11.2 deletion syndrome. J Neurodev Disord. 2011 Mar; 3(1):76-85. Stoddard J, Beckett L, Simon TJ. PMID: 21475729.
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    64. How might stress contribute to increased risk for schizophrenia in children with chromosome 22q11.2 deletion syndrome? J Neurodev Disord. 2011 Mar; 3(1):68-75. Beaton EA, Simon TJ. PMID: 21475728.
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    65. 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci. 2010 Jun; 11(6):402-16. Karayiorgou M, Simon TJ, Gogos JA. PMID: 20485365.
      View in: PubMed   Mentions: 175     Fields:    Translation:HumansAnimalsCells
    66. Atypical functional brain activation during a multiple object tracking task in girls with Turner syndrome: neurocorrelates of reduced spatiotemporal resolution. Am J Intellect Dev Disabil. 2010 Mar; 115(2):140-56. Beaton EA, Stoddard J, Lai S, Lackey J, Shi J, Ross JL, Simon TJ. PMID: 20441384.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    67. Rewards and challenges of cognitive neuroscience studies of persons with intellectual and developmental disabilities. Am J Intellect Dev Disabil. 2010 Mar; 115(2):79-82. Simon TJ. PMID: 20441387.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    68. Increased incidence and size of cavum septum pellucidum in children with chromosome 22q11.2 deletion syndrome. Psychiatry Res. 2010 Feb 28; 181(2):108-13. Beaton EA, Qin Y, Nguyen V, Johnson J, Pinter JD, Simon TJ. PMID: 20074913.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    69. Attenuated positive symptoms of psychosis in adolescents with chromosome 22q11.2 deletion syndrome. Schizophr Res. 2010 May; 118(1-3):118-21. Stoddard J, Niendam T, Hendren R, Carter C, Simon TJ. PMID: 20056393.
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    70. Catechol-O-methyltransferase polymorphism modulates cognitive control in children with chromosome 22q11.2 deletion syndrome. Cogn Affect Behav Neurosci. 2009 Mar; 9(1):83-90. Takarae Y, Schmidt L, Tassone F, Simon TJ. PMID: 19246329.
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    71. Structure-Specific Statistical Mapping of White Matter Tracts. . 2009 Jan 1; 83-112. Paul A. Yushkevich, Hui Zhang, Tony J. Simon, James C. Gee. .
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    72. Atypical cortical connectivity and visuospatial cognitive impairments are related in children with chromosome 22q11.2 deletion syndrome. Behav Brain Funct. 2008 Jun 17; 4:25. Simon TJ, Wu Z, Avants B, Zhang H, Gee JC, Stebbins GT. PMID: 18559106.
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    73. Alterations in midline cortical thickness and gyrification patterns mapped in children with 22q11.2 deletions. Cereb Cortex. 2009 Jan; 19(1):115-26. Bearden CE, van Erp TG, Dutton RA, Lee AD, Simon TJ, Cannon TD, Emanuel BS, McDonald-McGinn D, Zackai EH, Thompson PM. PMID: 18483006.
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    74. SURFACE-BASED MODELING OF WHITE MATTER FASCICULI WITH ORIENTATION ENCODING. . 2008 May 1; 708-711. Hui Zhang, Paul A. Yushkevich, Tony J Simon, James C. Gee. .
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    75. Structure-specific statistical mapping of white matter tracts. Neuroimage. 2008 Jun; 41(2):448-61. Yushkevich PA, Zhang H, Simon TJ, Gee JC. PMID: 18407524.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    76. A new account of the neurocognitive foundations of impairments in space, time and number processing in children with chromosome 22q11.2 deletion syndrome. Dev Disabil Res Rev. 2008; 14(1):52-8. Simon TJ. PMID: 18612330.
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    77. Brief report: methods for acquiring structural MRI data in very young children with autism without the use of sedation. J Autism Dev Disord. 2008 Sep; 38(8):1581-90. Nordahl CW, Simon TJ, Zierhut C, Solomon M, Rogers SJ, Amaral DG. PMID: 18157624.
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    78. Hippocampal volume reduction in children with chromosome 22q11.2 deletion syndrome is associated with cognitive impairment. Behav Brain Funct. 2007 Oct 23; 3:54. Deboer T, Wu Z, Lee A, Simon TJ. PMID: 17956622.
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    79. Shape-based normalization of the corpus callosum for DTI connectivity analysis. IEEE Trans Med Imaging. 2007 Sep; 26(9):1166-78. Sun H, Yushkevich PA, Zhang H, Cook PA, Duda JT, Simon TJ, Gee JC. PMID: 17896590.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    80. Overlapping numerical cognition impairments in children with chromosome 22q11.2 deletion or Turner syndromes. Neuropsychologia. 2008 Jan 15; 46(1):82-94. Simon TJ, Takarae Y, DeBoer T, McDonald-McGinn DM, Zackai EH, Ross JL. PMID: 17920087.
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    81. Cognitive characteristics of children with genetic syndromes. Child Adolesc Psychiatr Clin N Am. 2007 Jul; 16(3):599-616. Simon TJ. PMID: 17562581.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    82. Domain specific attentional impairments in children with chromosome 22q11.2 deletion syndrome. Brain Cogn. 2007 Aug; 64(3):265-73. Bish JP, Chiodo R, Mattei V, Simon TJ. PMID: 17499412.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    83. Evaluation of shape-based normalization in the corpus callosum for white matter connectivity analysis. Med Image Comput Comput Assist Interv. 2007; 10(Pt 2):777-84. Sun H, Yushkevich PA, Zhang H, Cook PA, Duda JT, Simon TJ, Gee JC. PMID: 18044639.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    84. Corpus callosum morphology and ventricular size in chromosome 22q11.2 deletion syndrome. Brain Res. 2007 Feb 02; 1131(1):197-210. Machado AM, Simon TJ, Nguyen V, McDonald-McGinn DM, Zackai EH, Gee JC. PMID: 17169351.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    85. Mapping cortical thickness in children with 22q11.2 deletions. Cereb Cortex. 2007 Aug; 17(8):1889-98. Bearden CE, van Erp TG, Dutton RA, Tran H, Zimmermann L, Sun D, Geaga JA, Simon TJ, Glahn DC, Cannon TD, Emanuel BS, Toga AW, Thompson PM. PMID: 17056649.
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    86. Specific cerebellar reductions in children with chromosome 22q11.2 deletion syndrome. Neurosci Lett. 2006 May 22; 399(3):245-8. Bish JP, Pendyal A, Ding L, Ferrante H, Nguyen V, McDonald-McGinn D, Zackai E, Simon TJ. PMID: 16517069.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    87. Efficient Generation of Shape-Based Reference Frames for the Corpus Callosum for DTI-based Connectivity Analysis. . 2006 Jan 1; 1-8. Hui Sun, Paul A. Yushkevich, Hui Zhang, James C. Gee, Tony J. Simon. .
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    88. Visuospatial and numerical cognitive deficits in children with chromosome 22q11.2 deletion syndrome. Cortex. 2005 Apr; 41(2):145-55. Simon TJ, Bearden CE, Mc-Ginn DM, Zackai E. PMID: 15714897.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCellsCTClinical Trials
    89. Effects of COMT genotype on behavioral symptomatology in the 22q11.2 Deletion Syndrome. Child Neuropsychol. 2005 Feb; 11(1):109-17. Bearden CE, Jawad AF, Lynch DR, Monterossso JR, Sokol S, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ. PMID: 15846854.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    90. Volumetric, connective, and morphologic changes in the brains of children with chromosome 22q11.2 deletion syndrome: an integrative study. Neuroimage. 2005 Mar; 25(1):169-80. Simon TJ, Ding L, Bish JP, McDonald-McGinn DM, Zackai EH, Gee J. PMID: 15734353.
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    91. A multilevel analysis of cognitive dysfunction and psychopathology associated with chromosome 22q11.2 deletion syndrome in children. Dev Psychopathol. 2005; 17(3):753-84. Simon TJ, Bish JP, Bearden CE, Ding L, Ferrante S, Nguyen V, Gee JC, McDonald-McGinn DM, Zackai EH, Emanuel BS. PMID: 16262991.
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    92. Maladaptive conflict monitoring as evidence for executive dysfunction in children with chromosome 22q11.2 deletion syndrome. Dev Sci. 2005 Jan; 8(1):36-43. Bish JP, Ferrante SM, McDonald-McGinn D, Zackai E, Simon TJ. PMID: 15647065.
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    93. Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome. Am J Psychiatry. 2004 Sep; 161(9):1700-2. Bearden CE, Jawad AF, Lynch DR, Sokol S, Kanes SJ, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ. PMID: 15337663.
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    94. Thalamic reductions in children with chromosome 22q11.2 deletion syndrome. Neuroreport. 2004 Jun 28; 15(9):1413-5. Bish JP, Nguyen V, Ding L, Ferrante S, Simon TJ. PMID: 15194864.
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    95. Regional brain abnormalities in 22q11.2 deletion syndrome: association with cognitive abilities and behavioral symptoms. Neurocase. 2004 Jun; 10(3):198-206. Bearden CE, van Erp TG, Monterosso JR, Simon TJ, Glahn DC, Saleh PA, Hill NM, McDonald-McGinn DM, Zackai E, Emanuel BS, Cannon TD. PMID: 15788257.
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    96. Williams syndrome cognitive profile also characterizes Velocardiofacial/DiGeorge syndrome. Am J Med Genet. 2002 Aug 08; 114(6):689-92. Bearden CE, Wang PP, Simon TJ. PMID: 12210289.
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    97. Cognitive development in VCFS. Progress in Pediatric Cardiology. 2002 Aug 1; 15(2):109-117. Tony J Simon, Carrie E Bearden, Edward M Moss, Donna McDonald-McGinn, Elaine Zackai, Paul P Wang. .
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    98. The foundations of numerical thinking in a brain without numbers. Trends Cogn Sci. 1999 Oct; 3(10):363-365. Simon TJ. PMID: 10498924.
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    99. Neural evidence linking visual object enumeration and attention. J Cogn Neurosci. 1999 Jan; 11(1):36-51. Sathian K, Simon TJ, Peterson S, Patel GA, Hoffman JM, Grafton ST. PMID: 9950713.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    100. Do the magnocellular and parvocellular visual pathways contribute differentially to subitizing and counting? Percept Psychophys. 1998 Apr; 60(3):451-64. Simon TJ, Peterson S, Patel G, Sathian K. PMID: 9599995.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    101. Subitizing and counting depend on different attentional mechanisms: evidence from visual enumeration in afterimages. Percept Psychophys. 1996 Aug; 58(6):915-26. Simon TJ, Vaishnavi S. PMID: 8768186.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    102. Do infants understand simple arithmetic? A replication of Wynn (1992). Cognitive Development. 1995 Apr 1; 10(2):253-269. Tony J. Simon, Susan J. Hespos, Philippe Rochat. .
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