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David R Hessl

Title(s)Professor, Psychiatry and Behavioral Sciences
SchoolUniversity of California, Davis
Phone916-703-0249
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    Collapse Research 
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    A Cognitive Test Battery for Intellectual Disabilities
    NIH/NICHD R01HD076189Sep 22, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Trajectories and Markers of Neurodegeneration in Fragile X Premutation Carriers
    NIH/NINDS R01NS110100Jun 1, 2007 - May 31, 2023
    Role: Co-Principal Investigator
    Trajectories and Markers of Neurodegeneration in Fragile X Premutation Carriers
    NIH/NIMH R01MH078041Jul 1, 2006 - Mar 31, 2018
    Role: Principal Investigator
    Genetics and Physiology of Social Anxiety in Fragile X
    NIH/NIMH K23MH077554Sep 30, 2005 - Jul 31, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wang JY, Hessl D, Tassone F, Kim K, Hagerman RJ, Rivera SM. Interaction between ventricular expansion and structural changes in the corpus callosum and putamen in males with FMR1 normal and premutation alleles. Neurobiol Aging. 2019 Sep 24. PMID: 31733943.
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    2. Hessl D, Schweitzer JB, Nguyen DV, McLennan YA, Johnston C, Shickman R, Chen Y. Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed. J Neurodev Disord. 2019 Apr 15; 11(1):4. PMID: 30982467.
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    3. Vismara LA, McCormick CEB, Shields R, Hessl D. Extending the Parent-Delivered Early Start Denver Model to Young Children with Fragile X Syndrome. J Autism Dev Disord. 2019 Mar; 49(3):1250-1266. PMID: 30499037.
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    4. Weber JD, Smith E, Berry-Kravis E, Cadavid D, Hessl D, Erickson C. Voice of People with Fragile X Syndrome and Their Families: Reports from a Survey on Treatment Priorities. Brain Sci. 2019 Jan 23; 9(2). PMID: 30678024.
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    5. Hessl D, Harvey D, Sansone S, Crestodina C, Chin J, Joshi R, Hagerman RJ, Berry-Kravis E. Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome. PLoS One. 2019; 14(1):e0209984. PMID: 30653533.
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    6. Schmitt LM, Shaffer RC, Hessl D, Erickson C. Executive Function in Fragile X Syndrome: A Systematic Review. Brain Sci. 2019 Jan 16; 9(1). PMID: 30654486.
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    7. Erickson CA, Kaufmann WE, Budimirovic DB, Lachiewicz A, Haas-Givler B, Miller RM, Weber JD, Abbeduto L, Hessl D, Hagerman RJ, Berry-Kravis E. Best Practices in Fragile X Syndrome Treatment Development. Brain Sci. 2018 Dec 15; 8(12). PMID: 30558274.
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    8. Al Olaby RR, Tang HT, Durbin-Johnson B, Schneider A, Hessl D, Rivera SM, Tassone F. Assessment of Molecular Measures in Non-FXTAS Male Premutation Carriers. Front Genet. 2018; 9:302. PMID: 30186307.
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    9. Famula JL, McKenzie F, McLennan YA, Grigsby J, Tassone F, Hessl D, Rivera SM, Martinez-Cerdeno V, Hagerman RJ. Presence of Middle Cerebellar Peduncle Sign in FMR1 Premutation Carriers Without Tremor and Ataxia. Front Neurol. 2018; 9:695. PMID: 30186228.
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    10. Shelton AL, Wang JY, Fourie E, Tassone F, Chen A, Frizzi L, Hagerman RJ, Ferrer E, Hessl D, Rivera SM. Middle Cerebellar Peduncle Width-A Novel MRI Biomarker for FXTAS? Front Neurosci. 2018; 12:379. PMID: 29988561.
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    11. Benyakorn S, Calub CA, Riley SJ, Schneider A, Iosif AM, Solomon M, Hessl D, Schweitzer JB. Computerized Cognitive Training in Children With Autism and Intellectual Disabilities: Feasibility and Satisfaction Study. JMIR Ment Health. 2018 May 25; 5(2):e40. PMID: 29802090.
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    12. Shickman R, Famula J, Tassone F, Leehey M, Ferrer E, Rivera SM, Hessl D. Age- and CGG repeat-related slowing of manual movement in fragile X carriers: A prodrome of fragile X-associated tremor ataxia syndrome? Mov Disord. 2018 04; 33(4):628-636. PMID: 29389022.
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    13. Thompson T, Coleman JM, Riley K, Snider LA, Howard LJ, Sansone SM, Hessl D. Standardized Assessment Accommodations for Individuals with Intellectual Disability. Contemp Sch Psychol. 2018 Dec; 22(4):443-457. PMID: 30420939.
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    14. Berry-Kravis EM, Lindemann L, Jønch AE, Apostol G, Bear MF, Carpenter RL, Crawley JN, Curie A, Des Portes V, Hossain F, Gasparini F, Gomez-Mancilla B, Hessl D, Loth E, Scharf SH, Wang PP, Von Raison F, Hagerman R, Spooren W, Jacquemont S. Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome. Nat Rev Drug Discov. 2018 04; 17(4):280-299. PMID: 29217836.
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    15. Youssef EA, Berry-Kravis E, Czech C, Hagerman RJ, Hessl D, Wong CY, Rabbia M, Deptula D, John A, Kinch R, Drewitt P, Lindemann L, Marcinowski M, Langland R, Horn C, Fontoura P, Santarelli L, Quiroz JA. Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results. Neuropsychopharmacology. 2018 02; 43(3):503-512. PMID: 28816242.
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    16. Ligsay A, Van Dijck A, Nguyen DV, Lozano R, Chen Y, Bickel ES, Hessl D, Schneider A, Angkustsiri K, Tassone F, Ceulemans B, Kooy RF, Hagerman RJ. A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome. J Neurodev Disord. 2017 Aug 02; 9(1):26. PMID: 28764646.
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    17. Erickson CA, Davenport MH, Schaefer TL, Wink LK, Pedapati EV, Sweeney JA, Fitzpatrick SE, Brown WT, Budimirovic D, Hagerman RJ, Hessl D, Kaufmann WE, Berry-Kravis E. Fragile X targeted pharmacotherapy: lessons learned and future directions. J Neurodev Disord. 2017; 9:7. PMID: 28616096.
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    18. Budimirovic DB, Berry-Kravis E, Erickson CA, Hall SS, Hessl D, Reiss AL, King MK, Abbeduto L, Kaufmann WE. Updated report on tools to measure outcomes of clinical trials in fragile X syndrome. J Neurodev Disord. 2017; 9:14. PMID: 28616097.
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    19. Jiraanont P, Sweha SR, AlOlaby RR, Silva M, Tang HT, Durbin-Johnson B, Schneider A, Espinal GM, Hagerman PJ, Rivera SM, Hessl D, Hagerman RJ, Chutabhakdikul N, Tassone F. Clinical and molecular correlates in fragile X premutation females. eNeurologicalSci. 2017 Jun; 7:49-56. PMID: 28971146.
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    20. Tartaglia NR, Wilson R, Miller JS, Rafalko J, Cordeiro L, Davis S, Hessl D, Ross J. Autism Spectrum Disorder in Males with Sex Chromosome Aneuploidy: XXY/Klinefelter Syndrome, XYY, and XXYY. J Dev Behav Pediatr. 2017 Apr; 38(3):197-207. PMID: 28333849.
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    21. Wang JY, Hessl D, Hagerman RJ, Simon TJ, Tassone F, Ferrer E, Rivera SM. Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation. Neurobiol Aging. 2017 07; 55:11-19. PMID: 28391068.
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    22. Greiss Hess L, Fitzpatrick SE, Nguyen DV, Chen Y, Gaul KN, Schneider A, Lemons Chitwood K, Eldeeb MA, Polussa J, Hessl D, Rivera S, Hagerman RJ. A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome. J Dev Behav Pediatr. 2016 10; 37(8):619-28. PMID: 27560971.
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    23. Lozano R, Saito N, Reed D, Eldeeb M, Schneider A, Hessl D, Tassone F, Beckett L, Hagerman R. Aging in Fragile X Premutation Carriers. Cerebellum. 2016 10; 15(5):587-94. PMID: 27334385.
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    24. Gossett A, Sansone S, Schneider A, Johnston C, Hagerman R, Tassone F, Rivera SM, Seritan AL, Hessl D. Psychiatric disorders among women with the?fragile X premutation without children affected by fragile X syndrome. Am J Med Genet B Neuropsychiatr Genet. 2016 12; 171(8):1139-1147. PMID: 27615674.
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    25. Hessl D, Sansone SM, Berry-Kravis E, Riley K, Widaman KF, Abbeduto L, Schneider A, Coleman J, Oaklander D, Rhodes KC, Gershon RC. The NIH Toolbox Cognitive Battery for intellectual disabilities: three preliminary studies and future directions. J Neurodev Disord. 2016; 8(1):35. PMID: 27602170.
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    26. Hessl D, Grigsby J. Fragile X-associated tremor/ataxia syndrome: another phenotype of the fragile X gene. Clin Neuropsychol. 2016 Aug; 30(6):810-4. PMID: 27355274.
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    27. Schneider A, Johnston C, Tassone F, Sansone S, Hagerman RJ, Ferrer E, Rivera SM, Hessl D. Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile X premutation. Clin Neuropsychol. 2016 08; 30(6):929-43. PMID: 27355445.
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    28. Wang JY, Ngo MM, Hessl D, Hagerman RJ, Rivera SM. Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem. PLoS One. 2016; 11(5):e0156123. PMID: 27213683.
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    29. Brick DJ, Nethercott HE, Montesano S, Banuelos MG, Stover AE, Schutte SS, O'Dowd DK, Hagerman RJ, Ono M, Hessl DR, Tassone F, Schwartz PH. The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery. Stem Cells Transl Med. 2015 Nov; 4(11):1369. PMID: 26508786.
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    30. Cordeiro L, Abucayan F, Hagerman R, Tassone F, Hessl D. Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands. Intractable Rare Dis Res. 2015 Aug; 4(3):123-30. PMID: 26361563.
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    31. Ballinger EC, Cordeiro L, Chavez AD, Hagerman RJ, Hessl D. Emotion potentiated startle in fragile X syndrome. J Autism Dev Disord. 2014 Oct; 44(10):2536-46. PMID: 24816942.
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    32. Brick DJ, Nethercott HE, Montesano S, Banuelos MG, Stover AE, Schutte SS, O'Dowd DK, Hagerman RJ, Ono M, Hessl DR, Tassone F, Schwartz PH. The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery. Stem Cells Transl Med. 2014 Nov; 3(11):1275-86. PMID: 25273538.
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    33. Au J, Berkowitz-Sutherland L, Schneider A, Schweitzer JB, Hessl D, Hagerman R. A feasibility trial of Cogmed working memory training in fragile X syndrome. J Pediatr Genet. 2014 Sep; 3(3):147-56. PMID: 27625871.
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    34. Sansone SM, Schneider A, Bickel E, Berry-Kravis E, Prescott C, Hessl D. Improving IQ measurement in intellectual disabilities using true deviation from population norms. J Neurodev Disord. 2014; 6(1):16. PMID: 26491488.
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    35. Lozano R, Summers S, Lozano C, Mu Y, Hessl D, Nguyen D, Tassone F, Hagerman R. Association between macroorchidism and intelligence in FMR1 premutation carriers. Am J Med Genet A. 2014 Sep; 164A(9):2206-11. PMID: 24903624.
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    36. McCormick C, Hessl D, Macari SL, Ozonoff S, Green C, Rogers SJ. Electrodermal and behavioral responses of children with autism spectrum disorders to sensory and repetitive stimuli. Autism Res. 2014 Aug; 7(4):468-80. PMID: 24788961.
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    37. Loesch DZ, Bui MQ, Hammersley E, Schneider A, Storey E, Stimpson P, Burgess T, Francis D, Slater H, Tassone F, Hagerman RJ, Hessl D. Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion. Clin Genet. 2015 Feb; 87(2):173-8. PMID: 24428240.
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    38. Russo-Ponsaran NM, Yesensky J, Hessl D, Berry-Kravis E. Feasibility, reproducibility, and clinical validity of the pediatric anxiety rating scale-revised for fragile X syndrome. Am J Intellect Dev Disabil. 2014 Jan; 119(1):1-16. PMID: 24450318.
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    39. Wheeler A, Raspa M, Bann C, Bishop E, Hessl D, Sacco P, Bailey DB. Anxiety, attention problems, hyperactivity, and the Aberrant Behavior Checklist in fragile X syndrome. Am J Med Genet A. 2014 Jan; 164A(1):141-55. PMID: 24352914.
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    40. Cohen S, Masyn K, Mastergeorge A, Hessl D. Psychophysiological responses to emotional stimuli in children and adolescents with autism and fragile X syndrome. J Clin Child Adolesc Psychol. 2015; 44(2):250-63. PMID: 24156344.
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    41. Berry-Kravis E, Hessl D, Abbeduto L, Reiss AL, Beckel-Mitchener A, Urv TK. Outcome measures for clinical trials in fragile X syndrome. J Dev Behav Pediatr. 2013 Sep; 34(7):508-22. PMID: 24042082.
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    42. Schneider A, Leigh MJ, Adams P, Nanakul R, Chechi T, Olichney J, Hagerman R, Hessl D. Electrocortical changes associated with minocycline treatment in fragile X syndrome. J Psychopharmacol. 2013 Oct; 27(10):956-63. PMID: 23981511.
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    43. Wang JY, Hessl D, Schneider A, Tassone F, Hagerman RJ, Rivera SM. Fragile X-associated tremor/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles. JAMA Neurol. 2013 Aug; 70(8):1022-9. PMID: 23753897.
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    44. Basuta K, Lozano R, Schneider A, Yrigollen CM, Hessl D, Hagerman RJ, Tassone F. A family with two female siblings with compound heterozygous FMR1 premutation alleles. Clin Genet. 2014 May; 85(5):458-63. PMID: 23786467.
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    45. Leigh MJ, Nguyen DV, Mu Y, Winarni TI, Schneider A, Chechi T, Polussa J, Doucet P, Tassone F, Rivera SM, Hessl D, Hagerman RJ. A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome. J Dev Behav Pediatr. 2013 Apr; 34(3):147-55. PMID: 23572165.
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    46. Wadell PM, Hagerman RJ, Hessl DR. FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES. Curr Psychiatry Rev. 2013 Feb 01; 9(1):53-58. PMID: 25632275.
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    47. Schneider A, Seritan A, Tassone F, Rivera SM, Hagerman R, Hessl D. Psychiatric features in high-functioning adult brothers with fragile x spectrum disorders. Prim Care Companion CNS Disord. 2013; 15(2). PMID: 23930232.
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    48. Kim SY, Burris J, Bassal F, Koldewyn K, Chattarji S, Tassone F, Hessl D, Rivera SM. Fear-specific amygdala function in children and adolescents on the fragile x spectrum: a dosage response of the FMR1 gene. Cereb Cortex. 2014 Mar; 24(3):600-13. PMID: 23146966.
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    49. Wang JM, Koldewyn K, Hashimoto R, Schneider A, Le L, Tassone F, Cheung K, Hagerman P, Hessl D, Rivera SM. Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding. Front Hum Neurosci. 2012; 6:297. PMID: 23115550.
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    50. Wang JY, Hessl D, Iwahashi C, Cheung K, Schneider A, Hagerman RJ, Hagerman PJ, Rivera SM. Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles. Neuroimage. 2013 Jan 15; 65:288-98. PMID: 23063447.
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    51. Berry-Kravis EM, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y, Nguyen DV, Gonzalez-Heydrich J, Wang PP, Carpenter RL, Bear MF, Hagerman RJ. Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci Transl Med. 2012 Sep 19; 4(152):152ra127. PMID: 22993294.
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    52. Sansone SM, Widaman KF, Hall SS, Reiss AL, Lightbody A, Kaufmann WE, Berry-Kravis E, Lachiewicz A, Brown EC, Hessl D. Psychometric study of the Aberrant Behavior Checklist in Fragile X Syndrome and implications for targeted treatment. J Autism Dev Disord. 2012 Jul; 42(7):1377-92. PMID: 21972117.
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    53. Hamlin AA, Sukharev D, Campos L, Mu Y, Tassone F, Hessl D, Nguyen DV, Loesch D, Hagerman RJ. Hypertension in FMR1 premutation males with and without fragile X-associated tremor/ataxia syndrome (FXTAS). Am J Med Genet A. 2012 Jun; 158A(6):1304-9. PMID: 22528549.
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    54. Wang JY, Hessl DH, Hagerman RJ, Tassone F, Rivera SM. Age-dependent structural connectivity effects in fragile x premutation. Arch Neurol. 2012 Apr; 69(4):482-9. PMID: 22491193.
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    55. Knox A, Schneider A, Abucayan F, Hervey C, Tran C, Hessl D, Berry-Kravis E. Feasibility, reliability, and clinical validity of the Test of Attentional Performance for Children (KiTAP) in Fragile X syndrome (FXS). J Neurodev Disord. 2012 Feb 08; 4(1):2. PMID: 22958782.
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    56. Selmeczy D, Koldewyn K, Wang JM, Lee A, Harvey D, Hessl DR, Tassone F, Adams P, Hagerman RJ, Hagerman PJ, Rivera SM. Investigation of amygdala volume in men with the fragile X premutation. Brain Imaging Behav. 2011 Dec; 5(4):285-94. PMID: 21786216.
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    57. Farzin F, Scaggs F, Hervey C, Berry-Kravis E, Hessl D. Reliability of eye tracking and pupillometry measures in individuals with fragile X syndrome. J Autism Dev Disord. 2011 Nov; 41(11):1515-22. PMID: 21267642.
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    58. Chonchaiya W, Au J, Schneider A, Hessl D, Harris SW, Laird M, Mu Y, Tassone F, Nguyen DV, Hagerman RJ. Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder. Hum Genet. 2012 Apr; 131(4):581-9. PMID: 22001913.
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    59. Hessl D, Wang JM, Schneider A, Koldewyn K, Le L, Iwahashi C, Cheung K, Tassone F, Hagerman PJ, Rivera SM. Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation. Biol Psychiatry. 2011 Nov 01; 70(9):859-65. PMID: 21783174.
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    60. Yuhas J, Cordeiro L, Tassone F, Ballinger E, Schneider A, Long JM, Ornitz EM, Hessl D. Brief report: Sensorimotor gating in idiopathic autism and autism associated with fragile X syndrome. J Autism Dev Disord. 2011 Feb; 41(2):248-53. PMID: 20521090.
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    61. Cordeiro L, Ballinger E, Hagerman R, Hessl D. Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization. J Neurodev Disord. 2011 Mar; 3(1):57-67. PMID: 21475730.
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    62. Schneider A, Ballinger E, Chavez A, Tassone F, Hagerman RJ, Hessl D. Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome. Neurobiol Aging. 2012 Jun; 33(6):1045-53. PMID: 20961665.
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    63. Chonchaiya W, Tassone F, Ashwood P, Hessl D, Schneider A, Campos L, Nguyen DV, Hagerman RJ. Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome. Hum Genet. 2010 Nov; 128(5):539-48. PMID: 20809278.
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    64. Bourgeois JA, Seritan AL, Casillas EM, Hessl D, Schneider A, Yang Y, Kaur I, Cogswell JB, Nguyen DV, Hagerman RJ. Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. J Clin Psychiatry. 2011 Feb; 72(2):175-82. PMID: 20816038.
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    65. Utari A, Adams E, Berry-Kravis E, Chavez A, Scaggs F, Ngotran L, Boyd A, Hessl D, Gane LW, Tassone F, Tartaglia N, Leehey MA, Hagerman RJ. Aging in fragile X syndrome. J Neurodev Disord. 2010 Jun; 2(2):70-76. PMID: 20585378.
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    66. Adams PE, Adams JS, Nguyen DV, Hessl D, Brunberg JA, Tassone F, Zhang W, Koldewyn K, Rivera SM, Grigsby J, Zhang L, Decarli C, Hagerman PJ, Hagerman RJ. Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers. Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 05; 153B(3):775-85. PMID: 19908235.
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    67. Ashwood P, Nguyen DV, Hessl D, Hagerman RJ, Tassone F. Plasma cytokine profiles in Fragile X subjects: is there a role for cytokines in the pathogenesis? Brain Behav Immun. 2010 Aug; 24(6):898-902. PMID: 20102735.
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    68. Chonchaiya W, Utari A, Pereira GM, Tassone F, Hessl D, Hagerman RJ. Broad clinical involvement in a family affected by the fragile X premutation. J Dev Behav Pediatr. 2009 Dec; 30(6):544-51. PMID: 19996900.
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    69. Hessl D, Berry-Kravis E, Cordeiro L, Yuhas J, Ornitz EM, Campbell A, Chruscinski E, Hervey C, Long JM, Hagerman RJ. Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment. Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 05; 150B(4):545-53. PMID: 18785205.
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    70. Bourgeois JA, Coffey SM, Rivera SM, Hessl D, Gane LW, Tassone F, Greco C, Finucane B, Nelson L, Berry-Kravis E, Grigsby J, Hagerman PJ, Hagerman RJ. A review of fragile X premutation disorders: expanding the psychiatric perspective. J Clin Psychiatry. 2009 Jun; 70(6):852-62. PMID: 19422761.
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    71. Farzin F, Rivera SM, Hessl D. Brief report: Visual processing of faces in individuals with fragile X syndrome: an eye tracking study. J Autism Dev Disord. 2009 Jun; 39(6):946-52. PMID: 19399604.
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    72. Solomon M, Hessl D, Chiu S, Olsen E, Hendren RL. Towards a neurodevelopmental model of clinical case formulation. Psychiatr Clin North Am. 2009 Mar; 32(1):199-211. PMID: 19248925.
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    73. Hessl D, Nguyen DV, Green C, Chavez A, Tassone F, Hagerman RJ, Senturk D, Schneider A, Lightbody A, Reiss AL, Hall S. A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome. J Neurodev Disord. 2009 Mar; 1(1):33-45. PMID: 19865612.
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    74. Berry-Kravis E, Hessl D, Coffey S, Hervey C, Schneider A, Yuhas J, Hutchison J, Snape M, Tranfaglia M, Nguyen DV, Hagerman R. A pilot open label, single dose trial of fenobam in adults with fragile X syndrome. J Med Genet. 2009 Apr; 46(4):266-71. PMID: 19126569.
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    75. Schneider A, Hagerman RJ, Hessl D. Fragile X syndrome -- from genes to cognition. Dev Disabil Res Rev. 2009; 15(4):333-42. PMID: 20014363.
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    76. Hagerman RJ, Berry-Kravis E, Kaufmann WE, Ono MY, Tartaglia N, Lachiewicz A, Kronk R, Delahunty C, Hessl D, Visootsak J, Picker J, Gane L, Tranfaglia M. Advances in the treatment of fragile X syndrome. Pediatrics. 2009 Jan; 123(1):378-90. PMID: 19117905.
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    77. Harris SW, Hessl D, Goodlin-Jones B, Ferranti J, Bacalman S, Barbato I, Tassone F, Hagerman PJ, Herman H, Hagerman RJ. Autism profiles of males with fragile X syndrome. Am J Ment Retard. 2008 Nov; 113(6):427-38. PMID: 19127654.
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    78. Zingerevich C, Greiss-Hess L, Lemons-Chitwood K, Harris SW, Hessl D, Cook K, Hagerman RJ. Motor abilities of children diagnosed with fragile X syndrome with and without autism. J Intellect Disabil Res. 2009 Jan; 53(1):11-8. PMID: 18771512.
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    79. García-Nonell C, Ratera ER, Harris S, Hessl D, Ono MY, Tartaglia N, Marvin E, Tassone F, Hagerman RJ. Secondary medical diagnosis in fragile X syndrome with and without autism spectrum disorder. Am J Med Genet A. 2008 Aug 01; 146A(15):1911-6. PMID: 18627038.
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    80. Brouwer JR, Severijnen E, de Jong FH, Hessl D, Hagerman RJ, Oostra BA, Willemsen R. Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome. Psychoneuroendocrinology. 2008 Jul; 33(6):863-73. PMID: 18472227.
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    81. Soontarapornchai K, Maselli R, Fenton-Farrell G, Tassone F, Hagerman PJ, Hessl D, Hagerman RJ. Abnormal nerve conduction features in fragile X premutation carriers. Arch Neurol. 2008 Apr; 65(4):495-8. PMID: 18413472.
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    82. Brega AG, Goodrich G, Bennett RE, Hessl D, Engle K, Leehey MA, Bounds LS, Paulich MJ, Hagerman RJ, Hagerman PJ, Cogswell JB, Tassone F, Reynolds A, Kooken R, Kenny M, Grigsby J. The primary cognitive deficit among males with fragile X-associated tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome. J Clin Exp Neuropsychol. 2008 Nov; 30(8):853-69. PMID: 18608667.
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    83. Koldewyn K, Hessl D, Adams J, Tassone F, Hagerman PJ, Hagerman RJ, Rivera SM. Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation. Brain Imaging Behav. 2008 Jan 18; 2(2):105-116. PMID: 19430586.
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