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David R Hessl, PhD

Title(s)Professor, Psychiatry and Behavioral Sciences
SchoolUniversity of California, Davis
AddressMIND Bldg/UCDMC
CA 95817
Phone916-703-0249
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    Collapse Research 
    Collapse Research Activities and Funding
    A Cognitive Test Battery for Intellectual Disabilities
    NIH/NICHD R01HD076189Sep 22, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Trajectories and Markers of Neurodegeneration in Fragile X Premutation Carriers
    NIH/NINDS R01NS110100Jun 1, 2007 - May 31, 2023
    Role: Co-Principal Investigator
    Trajectories and Markers of Neurodegeneration in Fragile X Premutation Carriers
    NIH/NIMH R01MH078041Jul 1, 2006 - Mar 31, 2018
    Role: Principal Investigator
    Genetics and Physiology of Social Anxiety in Fragile X
    NIH/NIMH K23MH077554Sep 30, 2005 - Jul 31, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Using the NIH Toolbox to Assess Cognition in Adolescents and Young Adults with Autism Spectrum Disorders. Autism Res. 2020 Oct 02. Solomon M, Gordon A, Iosif AM, Geddert R, Krug MK, Mundy P, Hessl D. PMID: 33006263.
      View in: PubMed   Mentions:    Fields:    
    2. Cognitive Training Deep Dive: The Impact of Child, Training Behavior and Environmental Factors within a Controlled Trial of Cogmed for Fragile X Syndrome. Brain Sci. 2020 Sep 25; 10(10). Scott H, Harvey DJ, Li Y, McLennan YA, Johnston CK, Shickman R, Piven J, Schweitzer JB, Hessl D. PMID: 32992879.
      View in: PubMed   Mentions:
    3. Response to Placebo in Fragile X Syndrome Clinical Trials: An Initial Analysis. Brain Sci. 2020 Sep 11; 10(9). Luu S, Province H, Berry-Kravis E, Hagerman R, Hessl D, Vaidya D, Lozano R, Rosselot H, Erickson C, Kaufmann WE, Budimirovic DB. PMID: 32932789.
      View in: PubMed   Mentions:
    4. FMR1 locus isoforms: potential biomarker candidates in fragile X-associated tremor/ataxia syndrome (FXTAS). Sci Rep. 2020 Jul 06; 10(1):11099. Zafarullah M, Tang HT, Durbin-Johnson B, Fourie E, Hessl D, Rivera SM, Tassone F. PMID: 32632326.
      View in: PubMed   Mentions:    Fields:    
    5. Validation of the NIH Toolbox Cognitive Battery in intellectual disability. Neurology. 2020 03 24; 94(12):e1229-e1240. Shields RH, Kaat AJ, McKenzie FJ, Drayton A, Sansone SM, Coleman J, Michalak C, Riley K, Berry-Kravis E, Gershon RC, Widaman KF, Hessl D. PMID: 32094241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions. PLoS One. 2019; 14(12):e0226811. Kim K, Hessl D, Randol JL, Espinal GM, Schneider A, Protic D, Aydin EY, Hagerman RJ, Hagerman PJ. PMID: 31891607.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Interaction between ventricular expansion and structural changes in the corpus callosum and putamen in males with FMR1 normal and premutation alleles. Neurobiol Aging. 2020 02; 86:27-38. Wang JY, Hessl D, Tassone F, Kim K, Hagerman RJ, Rivera SM. PMID: 31733943.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Cognitive training for children and adolescents with fragile X syndrome: a randomized controlled trial of Cogmed. J Neurodev Disord. 2019 04 15; 11(1):4. Hessl D, Schweitzer JB, Nguyen DV, McLennan YA, Johnston C, Shickman R, Chen Y. PMID: 30982467.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Extending the Parent-Delivered Early Start Denver Model to Young Children with Fragile X Syndrome. J Autism Dev Disord. 2019 Mar; 49(3):1250-1266. Vismara LA, McCormick CEB, Shields R, Hessl D. PMID: 30499037.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Voice of People with Fragile X Syndrome and Their Families: Reports from a Survey on Treatment Priorities. Brain Sci. 2019 Jan 23; 9(2). Weber JD, Smith E, Berry-Kravis E, Cadavid D, Hessl D, Erickson C. PMID: 30678024.
      View in: PubMed   Mentions:
    11. Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome. PLoS One. 2019; 14(1):e0209984. Hessl D, Harvey D, Sansone S, Crestodina C, Chin J, Joshi R, Hagerman RJ, Berry-Kravis E. PMID: 30653533.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Executive Function in Fragile X Syndrome: A Systematic Review. Brain Sci. 2019 Jan 16; 9(1). Schmitt LM, Shaffer RC, Hessl D, Erickson C. PMID: 30654486.
      View in: PubMed   Mentions:
    13. Best Practices in Fragile X Syndrome Treatment Development. Brain Sci. 2018 Dec 15; 8(12). Erickson CA, Kaufmann WE, Budimirovic DB, Lachiewicz A, Haas-Givler B, Miller RM, Weber JD, Abbeduto L, Hessl D, Hagerman RJ, Berry-Kravis E. PMID: 30558274.
      View in: PubMed   Mentions:
    14. Presence of Middle Cerebellar Peduncle Sign in FMR1 Premutation Carriers Without Tremor and Ataxia. Front Neurol. 2018; 9:695. Famula JL, McKenzie F, McLennan YA, Grigsby J, Tassone F, Hessl D, Rivera SM, Martinez-Cerdeno V, Hagerman RJ. PMID: 30186228.
      View in: PubMed   Mentions:
    15. Assessment of Molecular Measures in Non-FXTAS Male Premutation Carriers. Front Genet. 2018; 9:302. Al Olaby RR, Tang HT, Durbin-Johnson B, Schneider A, Hessl D, Rivera SM, Tassone F. PMID: 30186307.
      View in: PubMed   Mentions:
    16. Middle Cerebellar Peduncle Width-A Novel MRI Biomarker for FXTAS? Front Neurosci. 2018; 12:379. Shelton AL, Wang JY, Fourie E, Tassone F, Chen A, Frizzi L, Hagerman RJ, Ferrer E, Hessl D, Rivera SM. PMID: 29988561.
      View in: PubMed   Mentions:
    17. Computerized Cognitive Training in Children With Autism and Intellectual Disabilities: Feasibility and Satisfaction Study. JMIR Ment Health. 2018 May 25; 5(2):e40. Benyakorn S, Calub CA, Riley SJ, Schneider A, Iosif AM, Solomon M, Hessl D, Schweitzer JB. PMID: 29802090.
      View in: PubMed   Mentions:
    18. Age- and CGG repeat-related slowing of manual movement in fragile X carriers: A prodrome of fragile X-associated tremor ataxia syndrome? Mov Disord. 2018 04; 33(4):628-636. Shickman R, Famula J, Tassone F, Leehey M, Ferrer E, Rivera SM, Hessl D. PMID: 29389022.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    19. Standardized Assessment Accommodations for Individuals with Intellectual Disability. Contemp Sch Psychol. 2018 Dec; 22(4):443-457. Thompson T, Coleman JM, Riley K, Snider LA, Howard LJ, Sansone SM, Hessl D. PMID: 30420939.
      View in: PubMed   Mentions:
    20. Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome. Nat Rev Drug Discov. 2018 04; 17(4):280-299. Berry-Kravis EM, Lindemann L, Jønch AE, Apostol G, Bear MF, Carpenter RL, Crawley JN, Curie A, Des Portes V, Hossain F, Gasparini F, Gomez-Mancilla B, Hessl D, Loth E, Scharf SH, Wang PP, Von Raison F, Hagerman R, Spooren W, Jacquemont S. PMID: 29217836.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    21. Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results. Neuropsychopharmacology. 2018 02; 43(3):503-512. Youssef EA, Berry-Kravis E, Czech C, Hagerman RJ, Hessl D, Wong CY, Rabbia M, Deptula D, John A, Kinch R, Drewitt P, Lindemann L, Marcinowski M, Langland R, Horn C, Fontoura P, Santarelli L, Quiroz JA. PMID: 28816242.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    22. A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome. J Neurodev Disord. 2017 Aug 02; 9(1):26. Ligsay A, Van Dijck A, Nguyen DV, Lozano R, Chen Y, Bickel ES, Hessl D, Schneider A, Angkustsiri K, Tassone F, Ceulemans B, Kooy RF, Hagerman RJ. PMID: 28764646.
      View in: PubMed   Mentions: 12     Fields:    
    23. Fragile X targeted pharmacotherapy: lessons learned and future directions. J Neurodev Disord. 2017; 9:7. Erickson CA, Davenport MH, Schaefer TL, Wink LK, Pedapati EV, Sweeney JA, Fitzpatrick SE, Brown WT, Budimirovic D, Hagerman RJ, Hessl D, Kaufmann WE, Berry-Kravis E. PMID: 28616096.
      View in: PubMed   Mentions: 23     Fields:    
    24. Updated report on tools to measure outcomes of clinical trials in fragile X syndrome. J Neurodev Disord. 2017; 9:14. Budimirovic DB, Berry-Kravis E, Erickson CA, Hall SS, Hessl D, Reiss AL, King MK, Abbeduto L, Kaufmann WE. PMID: 28616097.
      View in: PubMed   Mentions: 24     Fields:    
    25. Clinical and molecular correlates in fragile X premutation females. eNeurologicalSci. 2017 Jun; 7:49-56. Jiraanont P, Sweha SR, AlOlaby RR, Silva M, Tang HT, Durbin-Johnson B, Schneider A, Espinal GM, Hagerman PJ, Rivera SM, Hessl D, Hagerman RJ, Chutabhakdikul N, Tassone F. PMID: 28971146.
      View in: PubMed   Mentions:
    26. Autism Spectrum Disorder in Males with Sex Chromosome Aneuploidy: XXY/Klinefelter Syndrome, XYY, and XXYY. J Dev Behav Pediatr. 2017 Apr; 38(3):197-207. Tartaglia NR, Wilson R, Miller JS, Rafalko J, Cordeiro L, Davis S, Hessl D, Ross J. PMID: 28333849.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    27. Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation. Neurobiol Aging. 2017 07; 55:11-19. Wang JY, Hessl D, Hagerman RJ, Simon TJ, Tassone F, Ferrer E, Rivera SM. PMID: 28391068.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    28. A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome. J Dev Behav Pediatr. 2016 10; 37(8):619-28. Greiss Hess L, Fitzpatrick SE, Nguyen DV, Chen Y, Gaul KN, Schneider A, Lemons Chitwood K, Eldeeb MA, Polussa J, Hessl D, Rivera S, Hagerman RJ. PMID: 27560971.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    29. Aging in Fragile X Premutation Carriers. Cerebellum. 2016 10; 15(5):587-94. Lozano R, Saito N, Reed D, Eldeeb M, Schneider A, Hessl D, Tassone F, Beckett L, Hagerman R. PMID: 27334385.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Psychiatric disorders among women with the?fragile X premutation without children affected by fragile X syndrome. Am J Med Genet B Neuropsychiatr Genet. 2016 12; 171(8):1139-1147. Gossett A, Sansone S, Schneider A, Johnston C, Hagerman R, Tassone F, Rivera SM, Seritan AL, Hessl D. PMID: 27615674.
      View in: PubMed   Mentions:
    31. The NIH Toolbox Cognitive Battery for intellectual disabilities: three preliminary studies and future directions. J Neurodev Disord. 2016; 8(1):35. Hessl D, Sansone SM, Berry-Kravis E, Riley K, Widaman KF, Abbeduto L, Schneider A, Coleman J, Oaklander D, Rhodes KC, Gershon RC. PMID: 27602170.
      View in: PubMed   Mentions: 16     Fields:    
    32. Fragile X-associated tremor/ataxia syndrome: another phenotype of the fragile X gene. Clin Neuropsychol. 2016 Aug; 30(6):810-4. Hessl D, Grigsby J. PMID: 27355274.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    33. Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile X premutation. Clin Neuropsychol. 2016 08; 30(6):929-43. Schneider A, Johnston C, Tassone F, Sansone S, Hagerman RJ, Ferrer E, Rivera SM, Hessl D. PMID: 27355445.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem. PLoS One. 2016; 11(5):e0156123. Wang JY, Ngo MM, Hessl D, Hagerman RJ, Rivera SM. PMID: 27213683.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    35. The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery. Stem Cells Transl Med. 2015 Nov; 4(11):1369. Brick DJ, Nethercott HE, Montesano S, Banuelos MG, Stover AE, Schutte SS, O'Dowd DK, Hagerman RJ, Ono M, Hessl DR, Tassone F, Schwartz PH. PMID: 26508786.
      View in: PubMed   Mentions:    Fields:    
    36. Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands. Intractable Rare Dis Res. 2015 Aug; 4(3):123-30. Cordeiro L, Abucayan F, Hagerman R, Tassone F, Hessl D. PMID: 26361563.
      View in: PubMed   Mentions:
    37. Emotion potentiated startle in fragile X syndrome. J Autism Dev Disord. 2014 Oct; 44(10):2536-46. Ballinger EC, Cordeiro L, Chavez AD, Hagerman RJ, Hessl D. PMID: 24816942.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery. Stem Cells Transl Med. 2014 Nov; 3(11):1275-86. Brick DJ, Nethercott HE, Montesano S, Banuelos MG, Stover AE, Schutte SS, O'Dowd DK, Hagerman RJ, Ono M, Hessl DR, Tassone F, Schwartz PH. PMID: 25273538.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsCTClinical Trials
    39. A feasibility trial of Cogmed working memory training in fragile X syndrome. J Pediatr Genet. 2014 Sep; 3(3):147-56. Au J, Berkowitz-Sutherland L, Schneider A, Schweitzer JB, Hessl D, Hagerman R. PMID: 27625871.
      View in: PubMed   Mentions:
    40. Improving IQ measurement in intellectual disabilities using true deviation from population norms. J Neurodev Disord. 2014; 6(1):16. Sansone SM, Schneider A, Bickel E, Berry-Kravis E, Prescott C, Hessl D. PMID: 26491488.
      View in: PubMed   Mentions: 23     Fields:    
    41. Association between macroorchidism and intelligence in FMR1 premutation carriers. . 2014 Sep; 164A(9):2206-11. Lozano R, Summers S, Lozano C, Mu Y, Hessl D, Nguyen D, Tassone F, Hagerman R. PMID: 24903624.
      View in: PubMed   Mentions:
    42. Electrodermal and behavioral responses of children with autism spectrum disorders to sensory and repetitive stimuli. Autism Res. 2014 Aug; 7(4):468-80. McCormick C, Hessl D, Macari SL, Ozonoff S, Green C, Rogers SJ. PMID: 24788961.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    43. Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion. Clin Genet. 2015 Feb; 87(2):173-8. Loesch DZ, Bui MQ, Hammersley E, Schneider A, Storey E, Stimpson P, Burgess T, Francis D, Slater H, Tassone F, Hagerman RJ, Hessl D. PMID: 24428240.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    44. Feasibility, reproducibility, and clinical validity of the pediatric anxiety rating scale-revised for fragile X syndrome. Am J Intellect Dev Disabil. 2014 Jan; 119(1):1-16. Russo-Ponsaran NM, Yesensky J, Hessl D, Berry-Kravis E. PMID: 24450318.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    45. Anxiety, attention problems, hyperactivity, and the Aberrant Behavior Checklist in fragile X syndrome. . 2014 Jan; 164A(1):141-55. Wheeler A, Raspa M, Bann C, Bishop E, Hessl D, Sacco P, Bailey DB. PMID: 24352914.
      View in: PubMed   Mentions:
    46. Psychophysiological responses to emotional stimuli in children and adolescents with autism and fragile X syndrome. J Clin Child Adolesc Psychol. 2015; 44(2):250-63. Cohen S, Masyn K, Mastergeorge A, Hessl D. PMID: 24156344.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    47. Outcome measures for clinical trials in fragile X syndrome. J Dev Behav Pediatr. 2013 Sep; 34(7):508-22. Berry-Kravis E, Hessl D, Abbeduto L, Reiss AL, Beckel-Mitchener A, Urv TK. PMID: 24042082.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    48. Electrocortical changes associated with minocycline treatment in fragile X syndrome. J Psychopharmacol. 2013 Oct; 27(10):956-63. Schneider A, Leigh MJ, Adams P, Nanakul R, Chechi T, Olichney J, Hagerman R, Hessl D. PMID: 23981511.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    49. Fragile X-associated tremor/ataxia syndrome: influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles. JAMA Neurol. 2013 Aug; 70(8):1022-9. Wang JY, Hessl D, Schneider A, Tassone F, Hagerman RJ, Rivera SM. PMID: 23753897.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    50. A family with two female siblings with compound heterozygous FMR1 premutation alleles. Clin Genet. 2014 May; 85(5):458-63. Basuta K, Lozano R, Schneider A, Yrigollen CM, Hessl D, Hagerman RJ, Tassone F. PMID: 23786467.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    51. A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome. J Dev Behav Pediatr. 2013 Apr; 34(3):147-55. Leigh MJ, Nguyen DV, Mu Y, Winarni TI, Schneider A, Chechi T, Polussa J, Doucet P, Tassone F, Rivera SM, Hessl D, Hagerman RJ. PMID: 23572165.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    52. FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES. Curr Psychiatry Rev. 2013 Feb 01; 9(1):53-58. Wadell PM, Hagerman RJ, Hessl DR. PMID: 25632275.
      View in: PubMed   Mentions:
    53. Psychiatric features in high-functioning adult brothers with fragile x spectrum disorders. Prim Care Companion CNS Disord. 2013; 15(2). Schneider A, Seritan A, Tassone F, Rivera SM, Hagerman R, Hessl D. PMID: 23930232.
      View in: PubMed   Mentions: 5     Fields:    
    54. Fear-specific amygdala function in children and adolescents on the fragile x spectrum: a dosage response of the FMR1 gene. Cereb Cortex. 2014 Mar; 24(3):600-13. Kim SY, Burris J, Bassal F, Koldewyn K, Chattarji S, Tassone F, Hessl D, Rivera SM. PMID: 23146966.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    55. Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding. Front Hum Neurosci. 2012; 6:297. Wang JM, Koldewyn K, Hashimoto R, Schneider A, Le L, Tassone F, Cheung K, Hagerman P, Hessl D, Rivera SM. PMID: 23115550.
      View in: PubMed   Mentions:
    56. Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles. Neuroimage. 2013 Jan 15; 65:288-98. Wang JY, Hessl D, Iwahashi C, Cheung K, Schneider A, Hagerman RJ, Hagerman PJ, Rivera SM. PMID: 23063447.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    57. Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci Transl Med. 2012 Sep 19; 4(152):152ra127. Berry-Kravis EM, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y, Nguyen DV, Gonzalez-Heydrich J, Wang PP, Carpenter RL, Bear MF, Hagerman RJ. PMID: 22993294.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCTClinical Trials
    58. Psychometric study of the Aberrant Behavior Checklist in Fragile X Syndrome and implications for targeted treatment. J Autism Dev Disord. 2012 Jul; 42(7):1377-92. Sansone SM, Widaman KF, Hall SS, Reiss AL, Lightbody A, Kaufmann WE, Berry-Kravis E, Lachiewicz A, Brown EC, Hessl D. PMID: 21972117.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    59. Hypertension in FMR1 premutation males with and without fragile X-associated tremor/ataxia syndrome (FXTAS). . 2012 Jun; 158A(6):1304-9. Hamlin AA, Sukharev D, Campos L, Mu Y, Tassone F, Hessl D, Nguyen DV, Loesch D, Hagerman RJ. PMID: 22528549.
      View in: PubMed   Mentions:
    60. Age-dependent structural connectivity effects in fragile x premutation. Arch Neurol. 2012 Apr; 69(4):482-9. Wang JY, Hessl DH, Hagerman RJ, Tassone F, Rivera SM. PMID: 22491193.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    61. Feasibility, reliability, and clinical validity of the Test of Attentional Performance for Children (KiTAP) in Fragile X syndrome (FXS). J Neurodev Disord. 2012 Feb 08; 4(1):2. Knox A, Schneider A, Abucayan F, Hervey C, Tran C, Hessl D, Berry-Kravis E. PMID: 22958782.
      View in: PubMed   Mentions: 15     Fields:    
    62. Investigation of amygdala volume in men with the fragile X premutation. Brain Imaging Behav. 2011 Dec; 5(4):285-94. Selmeczy D, Koldewyn K, Wang JM, Lee A, Harvey D, Hessl DR, Tassone F, Adams P, Hagerman RJ, Hagerman PJ, Rivera SM. PMID: 21786216.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    63. Reliability of eye tracking and pupillometry measures in individuals with fragile X syndrome. J Autism Dev Disord. 2011 Nov; 41(11):1515-22. Farzin F, Scaggs F, Hervey C, Berry-Kravis E, Hessl D. PMID: 21267642.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    64. Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder. Hum Genet. 2012 Apr; 131(4):581-9. Chonchaiya W, Au J, Schneider A, Hessl D, Harris SW, Laird M, Mu Y, Tassone F, Nguyen DV, Hagerman RJ. PMID: 22001913.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    65. Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation. Biol Psychiatry. 2011 Nov 01; 70(9):859-65. Hessl D, Wang JM, Schneider A, Koldewyn K, Le L, Iwahashi C, Cheung K, Tassone F, Hagerman PJ, Rivera SM. PMID: 21783174.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    66. Brief report: Sensorimotor gating in idiopathic autism and autism associated with fragile X syndrome. J Autism Dev Disord. 2011 Feb; 41(2):248-53. Yuhas J, Cordeiro L, Tassone F, Ballinger E, Schneider A, Long JM, Ornitz EM, Hessl D. PMID: 20521090.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    67. Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization. J Neurodev Disord. 2011 Mar; 3(1):57-67. Cordeiro L, Ballinger E, Hagerman R, Hessl D. PMID: 21475730.
      View in: PubMed   Mentions: 95     Fields:    
    68. Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome. Neurobiol Aging. 2012 Jun; 33(6):1045-53. Schneider A, Ballinger E, Chavez A, Tassone F, Hagerman RJ, Hessl D. PMID: 20961665.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    69. Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome. Hum Genet. 2010 Nov; 128(5):539-48. Chonchaiya W, Tassone F, Ashwood P, Hessl D, Schneider A, Campos L, Nguyen DV, Hagerman RJ. PMID: 20809278.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    70. Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. J Clin Psychiatry. 2011 Feb; 72(2):175-82. Bourgeois JA, Seritan AL, Casillas EM, Hessl D, Schneider A, Yang Y, Kaur I, Cogswell JB, Nguyen DV, Hagerman RJ. PMID: 20816038.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    71. Aging in fragile X syndrome. J Neurodev Disord. 2010 Jun; 2(2):70-76. Utari A, Adams E, Berry-Kravis E, Chavez A, Scaggs F, Ngotran L, Boyd A, Hessl D, Gane LW, Tassone F, Tartaglia N, Leehey MA, Hagerman RJ. PMID: 20585378.
      View in: PubMed   Mentions: 22     Fields:    
    72. Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers. . 2010 Apr 05; 153B(3):775-85. Adams PE, Adams JS, Nguyen DV, Hessl D, Brunberg JA, Tassone F, Zhang W, Koldewyn K, Rivera SM, Grigsby J, Zhang L, Decarli C, Hagerman PJ, Hagerman RJ. PMID: 19908235.
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    74. Broad clinical involvement in a family affected by the fragile X premutation. J Dev Behav Pediatr. 2009 Dec; 30(6):544-51. Chonchaiya W, Utari A, Pereira GM, Tassone F, Hessl D, Hagerman RJ. PMID: 19996900.
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    75. Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment. . 2009 Jun 05; 150B(4):545-53. Hessl D, Berry-Kravis E, Cordeiro L, Yuhas J, Ornitz EM, Campbell A, Chruscinski E, Hervey C, Long JM, Hagerman RJ. PMID: 18785205.
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    77. Brief report: Visual processing of faces in individuals with fragile X syndrome: an eye tracking study. J Autism Dev Disord. 2009 Jun; 39(6):946-52. Farzin F, Rivera SM, Hessl D. PMID: 19399604.
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    78. A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome. J Neurodev Disord. 2009 Mar; 1(1):33-45. Hessl D, Nguyen DV, Green C, Chavez A, Tassone F, Hagerman RJ, Senturk D, Schneider A, Lightbody A, Reiss AL, Hall S. PMID: 19865612.
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    80. A pilot open label, single dose trial of fenobam in adults with fragile X syndrome. J Med Genet. 2009 Apr; 46(4):266-71. Berry-Kravis E, Hessl D, Coffey S, Hervey C, Schneider A, Yuhas J, Hutchison J, Snape M, Tranfaglia M, Nguyen DV, Hagerman R. PMID: 19126569.
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    81. Fragile X syndrome -- from genes to cognition. Dev Disabil Res Rev. 2009; 15(4):333-42. Schneider A, Hagerman RJ, Hessl D. PMID: 20014363.
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    82. Advances in the treatment of fragile X syndrome. Pediatrics. 2009 Jan; 123(1):378-90. Hagerman RJ, Berry-Kravis E, Kaufmann WE, Ono MY, Tartaglia N, Lachiewicz A, Kronk R, Delahunty C, Hessl D, Visootsak J, Picker J, Gane L, Tranfaglia M. PMID: 19117905.
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    83. Autism profiles of males with fragile X syndrome. Am J Ment Retard. 2008 Nov; 113(6):427-38. Harris SW, Hessl D, Goodlin-Jones B, Ferranti J, Bacalman S, Barbato I, Tassone F, Hagerman PJ, Herman H, Hagerman RJ. PMID: 19127654.
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    84. Motor abilities of children diagnosed with fragile X syndrome with and without autism. J Intellect Disabil Res. 2009 Jan; 53(1):11-8. Zingerevich C, Greiss-Hess L, Lemons-Chitwood K, Harris SW, Hessl D, Cook K, Hagerman RJ. PMID: 18771512.
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    85. Secondary medical diagnosis in fragile X syndrome with and without autism spectrum disorder. . 2008 Aug 01; 146A(15):1911-6. García-Nonell C, Ratera ER, Harris S, Hessl D, Ono MY, Tartaglia N, Marvin E, Tassone F, Hagerman RJ. PMID: 18627038.
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    87. Abnormal nerve conduction features in fragile X premutation carriers. Arch Neurol. 2008 Apr; 65(4):495-8. Soontarapornchai K, Maselli R, Fenton-Farrell G, Tassone F, Hagerman PJ, Hessl D, Hagerman RJ. PMID: 18413472.
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    88. The primary cognitive deficit among males with fragile X-associated tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome. J Clin Exp Neuropsychol. 2008 Nov; 30(8):853-69. Brega AG, Goodrich G, Bennett RE, Hessl D, Engle K, Leehey MA, Bounds LS, Paulich MJ, Hagerman RJ, Hagerman PJ, Cogswell JB, Tassone F, Reynolds A, Kooken R, Kenny M, Grigsby J. PMID: 18608667.
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    89. Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation. Brain Imaging Behav. 2008 Jan 18; 2(2):105-116. Koldewyn K, Hessl D, Adams J, Tassone F, Hagerman PJ, Hagerman RJ, Rivera SM. PMID: 19430586.
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    91. Cognitive, anxiety and mood disorders in the fragile X-associated tremor/ataxia syndrome. Gen Hosp Psychiatry. 2007 Jul-Aug; 29(4):349-56. Bourgeois JA, Cogswell JB, Hessl D, Zhang L, Ono MY, Tassone F, Farzin F, Brunberg JA, Grigsby J, Hagerman RJ. PMID: 17591512.
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    92. Recommendations from multi-disciplinary focus groups on cascade testing and genetic counseling for fragile X-associated disorders. J Genet Couns. 2007 Oct; 16(5):593-606. McConkie-Rosell A, Abrams L, Finucane B, Cronister A, Gane LW, Coffey SM, Sherman S, Nelson LM, Berry-Kravis E, Hessl D, Chiu S, Street N, Vatave A, Hagerman RJ. PMID: 17497108.
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    93. Impairment of executive cognitive functioning in males with fragile X-associated tremor/ataxia syndrome. Mov Disord. 2007 Apr 15; 22(5):645-50. Grigsby J, Brega AG, Leehey MA, Goodrich GK, Jacquemont S, Loesch DZ, Cogswell JB, Epstein J, Wilson R, Jardini T, Gould E, Bennett RE, Hessl D, Cohen S, Cook K, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 17266074.
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    94. A genetic etiology of pervasive developmental disorder guides treatment. Am J Psychiatry. 2007 Apr; 164(4):575-80. Solomon M, Hessl D, Chiu S, Hagerman R, Hendren R. PMID: 17403969.
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    95. Brief report: aggression and stereotypic behavior in males with fragile X syndrome--moderating secondary genes in a "single gene" disorder. J Autism Dev Disord. 2008 Jan; 38(1):184-9. Hessl D, Tassone F, Cordeiro L, Koldewyn K, McCormick C, Green C, Wegelin J, Yuhas J, Hagerman RJ. PMID: 17340199.
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    96. Early acceleration of head circumference in children with fragile x syndrome and autism. J Dev Behav Pediatr. 2007 Feb; 28(1):31-5. Chiu S, Wegelin JA, Blank J, Jenkins M, Day J, Hessl D, Tassone F, Hagerman R. PMID: 17353729.
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    97. Progression of tremor and ataxia in male carriers of the FMR1 premutation. Mov Disord. 2007 Jan 15; 22(2):203-6. Leehey MA, Berry-Kravis E, Min SJ, Hall DA, Rice CD, Zhang L, Grigsby J, Greco CM, Reynolds A, Lara R, Cogswell J, Jacquemont S, Hessl DR, Tassone F, Hagerman R, Hagerman PJ. PMID: 17133502.
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    98. Amygdala dysfunction in men with the fragile X premutation. Brain. 2007 Feb; 130(Pt 2):404-16. Hessl D, Rivera S, Koldewyn K, Cordeiro L, Adams J, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 17166860.
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    99. Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X. Neurosci Biobehav Rev. 2007; 31(3):315-26. Loesch DZ, Bui QM, Dissanayake C, Clifford S, Gould E, Bulhak-Paterson D, Tassone F, Taylor AK, Hessl D, Hagerman R, Huggins RM. PMID: 17097142.
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    100. Molecular and imaging correlates of the fragile X-associated tremor/ataxia syndrome. Neurology. 2006 Oct 24; 67(8):1426-31. Cohen S, Masyn K, Adams J, Hessl D, Rivera S, Tassone F, Brunberg J, DeCarli C, Zhang L, Cogswell J, Loesch D, Leehey M, Grigsby J, Hagerman PJ, Hagerman R. PMID: 17060569.
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    101. Social behavior and cortisol reactivity in children with fragile X syndrome. J Child Psychol Psychiatry. 2006 Jun; 47(6):602-10. Hessl D, Glaser B, Dyer-Friedman J, Reiss AL. PMID: 16712637.
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    102. Autism spectrum disorders and attention-deficit/hyperactivity disorder in boys with the fragile X premutation. J Dev Behav Pediatr. 2006 Apr; 27(2 Suppl):S137-44. Farzin F, Perry H, Hessl D, Loesch D, Cohen J, Bacalman S, Gane L, Tassone F, Hagerman P, Hagerman R. PMID: 16685180.
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    103. Dementia with mood symptoms in a fragile X premutation carrier with the fragile X-associated tremor/ataxia syndrome: clinical intervention with donepezil and venlafaxine. J Neuropsychiatry Clin Neurosci. 2006; 18(2):171-7. Bourgeois JA, Farzin F, Brunberg JA, Tassone F, Hagerman P, Zhang L, Hessl D, Hagerman R. PMID: 16720793.
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    105. Abnormal elevation of FMR1 mRNA is associated with psychological symptoms in individuals with the fragile X premutation. . 2005 Nov 05; 139B(1):115-21. Hessl D, Tassone F, Loesch DZ, Berry-Kravis E, Leehey MA, Gane LW, Barbato I, Rice C, Gould E, Hall DA, Grigsby J, Wegelin JA, Harris S, Lewin F, Weinberg D, Hagerman PJ, Hagerman RJ. PMID: 16184602.
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    107. Fragile-X-associated tremor/ataxia syndrome (FXTAS) in females with the FMR1 premutation. Am J Hum Genet. 2004 May; 74(5):1051-6. Hagerman RJ, Leavitt BR, Farzin F, Jacquemont S, Greco CM, Brunberg JA, Tassone F, Hessl D, Harris SW, Zhang L, Jardini T, Gane LW, Ferranti J, Ruiz L, Leehey MA, Grigsby J, Hagerman PJ. PMID: 15065016.
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    108. The neuroanatomy and neuroendocrinology of fragile X syndrome. Ment Retard Dev Disabil Res Rev. 2004; 10(1):17-24. Hessl D, Rivera SM, Reiss AL. PMID: 14994284.
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    109. Factors associated with parenting stress in mothers of children with fragile X syndrome. J Dev Behav Pediatr. 2003 Aug; 24(4):267-75. Johnston C, Hessl D, Blasey C, Eliez S, Erba H, Dyer-Friedman J, Glaser B, Reiss AL. PMID: 12915799.
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    110. Preschool outcomes of children of depressed mothers: role of maternal behavior, contextual risk, and children's brain activity. Child Dev. 2003 Jul-Aug; 74(4):1158-75. Dawson G, Ashman SB, Panagiotides H, Hessl D, Self J, Yamada E, Embry L. PMID: 12938711.
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    111. Biological and environmental contributions to adaptive behavior in fragile X syndrome. . 2003 Feb 15; 117A(1):21-9. Glaser B, Hessl D, Dyer-Friedman J, Johnston C, Wisbeck J, Taylor A, Reiss A. PMID: 12548736.
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    113. Diurnal salivary cortisol in pediatric posttraumatic stress disorder. Biol Psychiatry. 2002 Apr 01; 51(7):575-82. Carrion VG, Weems CF, Ray RD, Glaser B, Hessl D, Reiss AL. PMID: 11950459.
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    114. Genetic and environmental influences on the cognitive outcomes of children with fragile X syndrome. J Am Acad Child Adolesc Psychiatry. 2002 Mar; 41(3):237-44. Dyer-Friedman J, Glaser B, Hessl D, Johnston C, Huffman LC, Taylor A, Wisbeck J, Reiss AL. PMID: 11886017.
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    115. fMRI study of cognitive interference processing in females with fragile X syndrome. J Cogn Neurosci. 2002 Feb 15; 14(2):160-71. Tamm L, Menon V, Johnston CK, Hessl DR, Reiss AL. PMID: 11970783.
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    118. Infants of depressed mothers exhibit atypical frontal electrical brain activity during interactions with mother and with a familiar, nondepressed adult. Child Dev. 1999 Sep-Oct; 70(5):1058-66. Dawson G, Frey K, Panagiotides H, Yamada E, Hessl D, Osterling J. PMID: 10546334.
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    119. Frontal brain electrical activity in infants of depressed and nondepressed mothers: relation to variations in infant behavior. Dev Psychopathol. 1999; 11(3):589-605. Dawson G, Frey K, Self J, Panagiotides H, Hessl D, Yamada E, Rinaldi J. PMID: 10532626.
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    120. Infants of depressed mothers exhibit atypical frontal brain activity: a replication and extension of previous findings. J Child Psychol Psychiatry. 1997 Feb; 38(2):179-86. Dawson G, Frey K, Panagiotides H, Osterling J, Hessl D. PMID: 9232464.
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