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Paul J Hagerman, MD; PhD

Title(s)Professor, Biochemistry and Molecular Medicine
SchoolUniversity of California, Davis
Address4455A Tupper Hall
CA 95616
Phone530-754-7266
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    Collapse Research 
    Collapse Research Activities and Funding
    Epigenetic regulation of the FMR1 gene
    NIH/NIGMS R01GM113929Sep 21, 2015 - May 31, 2019
    Role: Principal Investigator
    Human iPSC neuronal models for early and late phases of FXTAS neurodegeneration
    NIH/NIA RC1AG036022Sep 30, 2009 - Aug 31, 2011
    Role: Principal Investigator
    Development of targeted therapeutic agents for the treatment of FXTAS (2 of 6)
    NIH/NIA RL1AG032119Sep 30, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Neuro Therapeutics Research Institute (1 of 6)
    NIH/NIDCR UL1DE019583Sep 15, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Neuro Therapeutics Research Institute
    NIH/NCRR UL1RR024922Sep 15, 2007 - Jun 30, 2012
    Role: Principal Investigator
    Fragile X-associated Tremor/Ataxia Syndrome
    NIH/NIA R01AG024488Jun 15, 2005 - May 31, 2011
    Role: Principal Investigator
    Neurological Phenotype in FMR1 Premutation Carriers
    NIH/NINDS R01NS043532Jul 1, 2002 - Jun 30, 2006
    Role: Principal Investigator
    Expression of the fragile X gene
    NIH/NICHD R01HD040661Apr 1, 2002 - Dec 31, 2016
    Role: Principal Investigator
    TRNA STRUCTURE IN SOLUTION
    NIH/NIGMS R01GM052557Aug 1, 1996 - Jul 31, 2001
    Role: Principal Investigator
    PROTEIN NUCLEIC ACID INTERACTIONS
    NIH/NIGMS R01GM035305Jul 1, 1985 - Jun 30, 2004
    Role: Principal Investigator
    FLEXIBILITY OF DNA
    NIH/NIGMS R01GM028293Jul 1, 1980 - Jun 30, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elevated FMR1-mRNA and lowered FMRP - A double-hit mechanism for psychiatric features in men with FMR1 premutations. Transl Psychiatry. 2020 Jun 23; 10(1):205. Schneider A, Winarni TI, Cabal-Herrera AM, Bacalman S, Gane L, Hagerman P, Tassone F, Hagerman R. PMID: 32576818.
      View in: PubMed   Mentions:    Fields:    
    2. Autofluorescence-based analyses of intranuclear inclusions of Fragile X-associated tremor/ataxia syndrome. Biotechniques. 2020 Jun 03. Ma L, Hagerman PJ. PMID: 32486839.
      View in: PubMed   Mentions:    Fields:    
    3. Developmental aspects of FXAND in a man with the FMR1 premutation. Mol Genet Genomic Med. 2020 Feb; 8(2):e1050. Santos E, Emeka-Nwonovo C, Wang JY, Schneider A, Tassone F, Hagerman P, Hagerman R. PMID: 31899609.
      View in: PubMed   Mentions: 1     Fields:    
    4. Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions. PLoS One. 2019; 14(12):e0226811. Kim K, Hessl D, Randol JL, Espinal GM, Schneider A, Protic D, Aydin EY, Hagerman RJ, Hagerman PJ. PMID: 31891607.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Composition of the Intranuclear Inclusions of Fragile X-associated Tremor/Ataxia Syndrome. Acta Neuropathol Commun. 2019 09 03; 7(1):143. Ma L, Herren AW, Espinal G, Randol J, McLaughlin B, Martinez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. PMID: 31481131.
      View in: PubMed   Mentions: 2     Fields:    
    6. Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology. Acta Neuropathol Commun. 2019 02 26; 7(1):27. Wenzel HJ, Murray KD, Haify SN, Hunsaker MR, Schwartzer JJ, Kim K, La Spada AR, Sopher BL, Hagerman PJ, Raske C, Severijnen LWFM, Willemsen R, Hukema RK, Berman RF. PMID: 30808398.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Microglial cell activation and senescence are characteristic of the pathology FXTAS. Mov Disord. 2018 12; 33(12):1887-1894. Martínez Cerdeño V, Hong T, Amina S, Lechpammer M, Ariza J, Tassone F, Noctor SC, Hagerman P, Hagerman R. PMID: 30537011.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Fragile X syndrome and connective tissue dysregulation. Clin Genet. 2019 02; 95(2):262-267. Ramírez-Cheyne JA, Duque GA, Ayala-Zapata S, Saldarriaga-Gil W, Hagerman P, Hagerman R, Payán-Gómez C. PMID: 30414172.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    9. Size and methylation mosaicism in males with Fragile X syndrome. Expert Rev Mol Diagn. 2017 11; 17(11):1023-1032. Jiraanont P, Kumar M, Tang HT, Espinal G, Hagerman PJ, Hagerman RJ, Chutabhakdikul N, Tassone F. PMID: 28929824.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Fragile X syndrome. Nat Rev Dis Primers. 2017 Sep 29; 3:17065. Hagerman RJ, Berry-Kravis E, Hazlett HC, Bailey DB, Moine H, Kooy RF, Tassone F, Gantois I, Sonenberg N, Mandel JL, Hagerman PJ. PMID: 28960184.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    11. Concomitant occurrence of FXTAS and clinically defined sporadic inclusion body myositis: report of two cases. Croat Med J. 2017 Aug 31; 58(4):310-315. Lechpammer M, Martínez Cerdeno V, Hunsaker MR, Hah M, Gonzales H, Tisch S, Joffe R, Pamphlett R, Tassone F, Hagerman PJ, Bolitho SJ, Hagerman RJ. PMID: 28857524.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2017 07 15; 26(14):2649-2666. Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN. PMID: 28444183.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    13. Two FMR1 premutation cases without nuclear inclusions. Mov Disord. 2017 09; 32(9):1328-1329. Martínez-Cerdeño V, Lechpammer M, Hagerman PJ, Hagerman R. PMID: 28568317.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Clinical and molecular correlates in fragile X premutation females. eNeurologicalSci. 2017 Jun; 7:49-56. Jiraanont P, Sweha SR, AlOlaby RR, Silva M, Tang HT, Durbin-Johnson B, Schneider A, Espinal GM, Hagerman PJ, Rivera SM, Hessl D, Hagerman RJ, Chutabhakdikul N, Tassone F. PMID: 28971146.
      View in: PubMed   Mentions:
    15. FMR1 premutation with Prader-Willi phenotype and fragile X-associated tremor/ataxia syndrome. Clin Case Rep. 2017 05; 5(5):625-629. Martínez-Cerdeño V, Lechpammer M, Noctor S, Ariza J, Hagerman P, Hagerman R. PMID: 28469864.
      View in: PubMed   Mentions:
    16. Iron accumulation and dysregulation in the putamen in fragile X-associated tremor/ataxia syndrome. Mov Disord. 2017 04; 32(4):585-591. Ariza J, Rogers H, Hartvigsen A, Snell M, Dill M, Judd D, Hagerman P, Martínez-Cerdeño V. PMID: 28233916.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    17. Cerebellar Mild Iron Accumulation in a Subset of FMR1 Premutation Carriers with FXTAS. Cerebellum. 2016 10; 15(5):641-4. Rogers H, Ariza J, Monterrubio A, Hagerman P, Martínez-Cerdeño V. PMID: 27259564.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    18. A Majority of FXTAS Cases Present with Intranuclear Inclusions Within Purkinje Cells. Cerebellum. 2016 10; 15(5):546-51. Ariza J, Rogers H, Monterrubio A, Reyes-Miranda A, Hagerman PJ, Martínez-Cerdeño V. PMID: 27108270.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    19. Fragile X-associated tremor/ataxia syndrome - features, mechanisms and management. Nat Rev Neurol. 2016 07; 12(7):403-12. Hagerman RJ, Hagerman P. PMID: 27340021.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    20. Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Sci Signal. 2016 06 07; 9(431):ra58. Kashima R, Roy S, Ascano M, Martinez-Cerdeno V, Ariza-Torres J, Kim S, Louie J, Lu Y, Leyton P, Bloch KD, Kornberg TB, Hagerman PJ, Hagerman R, Lagna G, Hata A. PMID: 27273096.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    21. Single-locus enrichment without amplification for sequencing and direct detection of epigenetic modifications. Mol Genet Genomics. 2016 Jun; 291(3):1491-504. Pham TT, Yin J, Eid JS, Adams E, Lam R, Turner SW, Loomis EW, Wang JY, Hagerman PJ, Hanes JW. PMID: 26825750.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Prenatal Diagnosis and the Spectrum of Involvement from Fragile X Mutations. . 2015 Oct 23; 350-365. Randi J. Hagerman, Paul J. Hagerman. .
      View in: Publisher Site   Mentions:
    23. Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS. Hum Mol Genet. 2015 Sep 01; 24(17):4948-57. Hukema RK, Buijsen RA, Schonewille M, Raske C, Severijnen LA, Nieuwenhuizen-Bakker I, Verhagen RF, van Dessel L, Maas A, Charlet-Berguerand N, De Zeeuw CI, Hagerman PJ, Berman RF, Willemsen R. PMID: 26060190.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    24. Fragile X-associated tremor/ataxia syndrome. Ann N Y Acad Sci. 2015 Mar; 1338:58-70. Hagerman PJ, Hagerman RJ. PMID: 25622649.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    25. Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome. Brain Res. 2015 Feb 19; 1598:88-96. Ariza J, Steward C, Rueckert F, Widdison M, Coffman R, Afjei A, Noctor SC, Hagerman R, Hagerman P, Martínez-Cerdeño V. PMID: 25498860.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    26. Differential increases of specific FMR1 mRNA isoforms in premutation carriers. J Med Genet. 2015 Jan; 52(1):42-52. Pretto DI, Eid JS, Yrigollen CM, Tang HT, Loomis EW, Raske C, Durbin-Johnson B, Hagerman PJ, Tassone F. PMID: 25358671.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    27. Clinical and molecular implications of mosaicism in FMR1 full mutations. Front Genet. 2014; 5:318. Pretto D, Yrigollen CM, Tang HT, Williamson J, Espinal G, Iwahashi CK, Durbin-Johnson B, Hagerman RJ, Hagerman PJ, Tassone F. PMID: 25278957.
      View in: PubMed   Mentions:
    28. ERP abnormalities elicited by word repetition in fragile X-associated tremor/ataxia syndrome (FXTAS) and amnestic MCI. Neuropsychologia. 2014 Oct; 63:34-42. Yang JC, Chi L, Teichholtz S, Schneider A, Nanakul R, Nowacki R, Seritan A, Reed B, DeCarli C, Iragui VJ, Kutas M, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 25111034.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Fragile x premutation. J Neurodev Disord. 2014; 6(1):22. Tassone F, Hagerman PJ, Hagerman RJ. PMID: 25170346.
      View in: PubMed   Mentions: 5     Fields:    
    30. High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects. Mitochondrion. 2014 Jul; 17:116-25. Sahdeo S, Tomilov A, Komachi K, Iwahashi C, Datta S, Hughes O, Hagerman P, Cortopassi G. PMID: 25034306.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    31. Memantine effects on verbal memory in fragile X-associated tremor/ataxia syndrome (FXTAS): a double-blind brain potential study. Neuropsychopharmacology. 2014 Nov; 39(12):2760-8. Yang JC, Niu YQ, Simon C, Seritan AL, Chen L, Schneider A, Moghaddam ST, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 24871547.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    32. Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans. Hum Mol Genet. 2014 Sep 15; 23(18):4945-59. Juang BT, Ludwig AL, Benedetti KL, Gu C, Collins K, Morales C, Asundi A, Wittmann T, L'Etoile N, Hagerman PJ. PMID: 24821701.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    33. Transcription-associated R-loop formation across the human FMR1 CGG-repeat region. PLoS Genet. 2014 Apr; 10(4):e1004294. Loomis EW, Sanz LA, Chédin F, Hagerman PJ. PMID: 24743386.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    34. Memantine for fragile X-associated tremor/ataxia syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2014 Mar; 75(3):264-71. Seritan AL, Nguyen DV, Mu Y, Tassone F, Bourgeois JA, Schneider A, Cogswell JB, Cook KR, Leehey MA, Grigsby J, Olichney JM, Adams PE, Legg W, Zhang L, Hagerman PJ, Hagerman RJ. PMID: 24345444.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    35. CNS expression of murine fragile X protein (FMRP) as a function of CGG-repeat size. Hum Mol Genet. 2014 Jun 15; 23(12):3228-38. Ludwig AL, Espinal GM, Pretto DI, Jamal AL, Arque G, Tassone F, Berman RF, Hagerman PJ. PMID: 24463622.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    36. Induced expression of expanded CGG RNA causes mitochondrial dysfunction in vivo. Cell Cycle. 2014; 13(16):2600-8. Hukema RK, Buijsen RA, Raske C, Severijnen LA, Nieuwenhuizen-Bakker I, Minneboo M, Maas A, de Crom R, Kros JM, Hagerman PJ, Berman RF, Willemsen R. PMID: 25486200.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    37. Abnormal semantic processing in females with fragile X-associated tremor/ataxia syndrome. Genes Brain Behav. 2014 Feb; 13(2):152-62. Yang JC, Simon C, Schneider A, Seritan AL, Hamilton L, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 24299169.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. Advances in clinical and molecular understanding of the FMR1 premutation and fragile X-associated tremor/ataxia syndrome. Lancet Neurol. 2013 Aug; 12(8):786-98. Hagerman R, Hagerman P. PMID: 23867198.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    39. Phenotypes of hypofrontality in older female fragile X premutation carriers. Ann Neurol. 2013 Aug; 74(2):275-83. Yang JC, Simon C, Niu YQ, Bogost M, Schneider A, Tassone F, Seritan A, Grigsby J, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 23686745.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    40. Fragile X-associated tremor/ataxia syndrome (FXTAS): pathology and mechanisms. Acta Neuropathol. 2013 Jul; 126(1):1-19. Hagerman P. PMID: 23793382.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    41. Intranuclear inclusions in a fragile X mosaic male. Transl Neurodegener. 2013 May 21; 2(1):10. Pretto DI, Hunsaker MR, Cunningham CL, Greco CM, Hagerman RJ, Noctor SC, Hall DA, Hagerman PJ, Tassone F. PMID: 23692864.
      View in: PubMed   Mentions:
    42. Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion. J Biol Chem. 2013 May 10; 288(19):13831-41. Cao Z, Hulsizer S, Cui Y, Pretto DL, Kim KH, Hagerman PJ, Tassone F, Pessah IN. PMID: 23553633.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    43. Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome. Cell Rep. 2013 Mar 28; 3(3):869-80. Sellier C, Freyermuth F, Tabet R, Tran T, He F, Ruffenach F, Alunni V, Moine H, Thibault C, Page A, Tassone F, Willemsen R, Disney MD, Hagerman PJ, Todd PK, Charlet-Berguerand N. PMID: 23478018.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    44. Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding. Front Hum Neurosci. 2012; 6:297. Wang JM, Koldewyn K, Hashimoto R, Schneider A, Le L, Tassone F, Cheung K, Hagerman P, Hessl D, Rivera SM. PMID: 23115550.
      View in: PubMed   Mentions:
    45. Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles. Neuroimage. 2013 Jan 15; 65:288-98. Wang JY, Hessl D, Iwahashi C, Cheung K, Schneider A, Hagerman RJ, Hagerman PJ, Rivera SM. PMID: 23063447.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    46. Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene. Genome Res. 2013 Jan; 23(1):121-8. Loomis EW, Eid JS, Peluso P, Yin J, Hickey L, Rank D, McCalmon S, Hagerman RJ, Tassone F, Hagerman PJ. PMID: 23064752.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    47. Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model. J Neurochem. 2012 Nov; 123(4):613-21. Kaplan ES, Cao Z, Hulsizer S, Tassone F, Berman RF, Hagerman PJ, Pessah IN. PMID: 22924671.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    48. Neural substrates of executive dysfunction in fragile X-associated tremor/ataxia syndrome (FXTAS): a brain potential study. Cereb Cortex. 2013 Nov; 23(11):2657-66. Yang JC, Chan SH, Khan S, Schneider A, Nanakul R, Teichholtz S, Niu YQ, Seritan A, Tassone F, Grigsby J, Hagerman PJ, Hagerman RJ, Olichney JM. PMID: 22918986.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    49. Immune-mediated disorders among women carriers of fragile X premutation alleles. Am J Med Genet A. 2012 Oct; 158A(10):2473-81. Winarni TI, Chonchaiya W, Sumekar TA, Ashwood P, Morales GM, Tassone F, Nguyen DV, Faradz SM, Van de Water J, Cook K, Hamlin A, Mu Y, Hagerman PJ, Hagerman RJ. PMID: 22903889.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    50. Signaling defects in iPSC-derived fragile X premutation neurons. Hum Mol Genet. 2012 Sep 01; 21(17):3795-805. Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. PMID: 22641815.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    51. Current Gaps in Understanding the Molecular Basis of FXTAS. Tremor Other Hyperkinet Mov (N Y). 2012; 2. Hagerman PJ. PMID: 23440729.
      View in: PubMed   Mentions: 15     Fields:    
    52. AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome. Genet Med. 2012 Aug; 14(8):729-36. Yrigollen CM, Durbin-Johnson B, Gane L, Nelson DL, Hagerman R, Hagerman PJ, Tassone F. PMID: 22498846.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    53. Reduced telomere length in individuals with FMR1 premutations and full mutations. Am J Med Genet A. 2012 May; 158A(5):1060-5. Jenkins EC, Tassone F, Ye L, Hoogeveen AT, Brown WT, Hagerman RJ, Hagerman PJ. PMID: 22489017.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    54. Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS. Genes Brain Behav. 2012 Jul; 11(5):577-85. Tassone F, Greco CM, Hunsaker MR, Seritan AL, Berman RF, Gane LW, Jacquemont S, Basuta K, Jin LW, Hagerman PJ, Hagerman RJ. PMID: 22463693.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    55. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 01; 21(13):2923-35. Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. PMID: 22466801.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    56. Fragile X-associated tremor/ataxia syndrome. Handb Clin Neurol. 2012; 103:373-86. Leehey MA, Hagerman PJ. PMID: 21827901.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    57. Investigation of amygdala volume in men with the fragile X premutation. Brain Imaging Behav. 2011 Dec; 5(4):285-94. Selmeczy D, Koldewyn K, Wang JM, Lee A, Harvey D, Hessl DR, Tassone F, Adams P, Hagerman RJ, Hagerman PJ, Rivera SM. PMID: 21786216.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    58. Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome. PLoS One. 2011; 6(8):e23648. Stöger R, Genereux DP, Hagerman RJ, Hagerman PJ, Tassone F, Laird CD. PMID: 21909353.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    59. Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice. Acta Neuropathol. 2011 Oct; 122(4):467-79. Hunsaker MR, Greco CM, Spath MA, Smits AP, Navarro CS, Tassone F, Kros JM, Severijnen LA, Berry-Kravis EM, Berman RF, Hagerman PJ, Willemsen R, Hagerman RJ, Hukema RK. PMID: 21785977.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    60. Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation. Biol Psychiatry. 2011 Nov 01; 70(9):859-65. Hessl D, Wang JM, Schneider A, Koldewyn K, Le L, Iwahashi C, Cheung K, Tassone F, Hagerman PJ, Rivera SM. PMID: 21783174.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    61. High-resolution methylation polymerase chain reaction for fragile X analysis: evidence for novel FMR1 methylation patterns undetected in Southern blot analyses. Genet Med. 2011 Jun; 13(6):528-538. Chen L, Hadd A, Sah S, Houghton JF, Filipovic-Sadic S, Zhang W, Hagerman PJ, Tassone F, Latham GJ. PMID: 21430544.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    62. Rare intranuclear inclusions in the brains of 3 older adult males with fragile x syndrome: implications for the spectrum of fragile x-associated disorders. J Neuropathol Exp Neurol. 2011 Jun; 70(6):462-9. Hunsaker MR, Greco CM, Tassone F, Berman RF, Willemsen R, Hagerman RJ, Hagerman PJ. PMID: 21572337.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    63. FMR1 premutation and full mutation molecular mechanisms related to autism. J Neurodev Disord. 2011 Sep; 3(3):211-24. Hagerman R, Au J, Hagerman P. PMID: 21617890.
      View in: PubMed   Mentions: 31     Fields:    
    64. FMR1 gray-zone alleles: association with Parkinson's disease in women? Mov Disord. 2011 Aug 15; 26(10):1900-6. Hall DA, Berry-Kravis E, Zhang W, Tassone F, Spector E, Zerbe G, Hagerman PJ, Ouyang B, Leehey MA. PMID: 21567456.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    65. Altered zinc transport disrupts mitochondrial protein processing/import in fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2011 Aug 01; 20(15):3079-92. Napoli E, Ross-Inta C, Wong S, Omanska-Klusek A, Barrow C, Iwahashi C, Garcia-Arocena D, Sakaguchi D, Berry-Kravis E, Hagerman R, Hagerman PJ, Giulivi C. PMID: 21558427.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    66. A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS. Curr Gerontol Geriatr Res. 2011; 2011:484713. Narcisa V, Aguilar D, Nguyen DV, Campos L, Brodovsky J, White S, Adams P, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 23008705.
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    67. Differential usage of transcriptional start sites and polyadenylation sites in FMR1 premutation alleles. Nucleic Acids Res. 2011 Aug; 39(14):6172-85. Tassone F, De Rubeis S, Carosi C, La Fata G, Serpa G, Raske C, Willemsen R, Hagerman PJ, Bagni C. PMID: 21478165.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    68. CGG-repeat length threshold for FMR1 RNA pathogenesis in a cellular model for FXTAS. Hum Mol Genet. 2011 Jun 01; 20(11):2161-70. Hoem G, Raske CR, Garcia-Arocena D, Tassone F, Sanchez E, Ludwig AL, Iwahashi CK, Kumar M, Yang JE, Hagerman PJ. PMID: 21389081.
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    69. Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol Autism. 2011 Feb 08; 2(1):2. Greco CM, Navarro CS, Hunsaker MR, Maezawa I, Shuler JF, Tassone F, Delany M, Au JW, Berman RF, Jin LW, Schumann C, Hagerman PJ, Hagerman RJ. PMID: 21303513.
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    70. Initiation of translation of the FMR1 mRNA Occurs predominantly through 5'-end-dependent ribosomal scanning. J Mol Biol. 2011 Mar 18; 407(1):21-34. Ludwig AL, Hershey JW, Hagerman PJ. PMID: 21237174.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    71. Epilepsy in autism spectrum disorders. Epilepsia. 2010 Dec 1; 51(s5):78-78. Carl E. Stafstrom, Paul J. Hagerman, Isaac N. Pessah. .
      View in: Publisher Site   Mentions:
    72. Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 01; 20(1):64-79. Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. PMID: 20935171.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    73. Fragile X and autism: Intertwined at the molecular level leading to targeted treatments. Mol Autism. 2010 Sep 21; 1(1):12. Hagerman R, Hoem G, Hagerman P. PMID: 20858229.
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    74. Evidence of mitochondrial dysfunction in fragile X-associated tremor/ataxia syndrome. Biochem J. 2010 Aug 01; 429(3):545-52. Ross-Inta C, Omanska-Klusek A, Wong S, Barrow C, Garcia-Arocena D, Iwahashi C, Berry-Kravis E, Hagerman RJ, Hagerman PJ, Giulivi C. PMID: 20513237.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    75. An information-rich CGG repeat primed PCR that detects the full range of fragile X expanded alleles and minimizes the need for southern blot analysis. J Mol Diagn. 2010 Sep; 12(5):589-600. Chen L, Hadd A, Sah S, Filipovic-Sadic S, Krosting J, Sekinger E, Pan R, Hagerman PJ, Stenzel TT, Tassone F, Latham GJ. PMID: 20616364.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    76. Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins. Neurotoxicology. 2010 Aug; 31(4):399-402. Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R. PMID: 20466021.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    77. Advances in understanding the molecular basis of FXTAS. Hum Mol Genet. 2010 Apr 15; 19(R1):R83-9. Garcia-Arocena D, Hagerman PJ. PMID: 20430935.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    78. Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers. Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 05; 153B(3):775-85. Adams PE, Adams JS, Nguyen DV, Hessl D, Brunberg JA, Tassone F, Zhang W, Koldewyn K, Rivera SM, Grigsby J, Zhang L, Decarli C, Hagerman PJ, Hagerman RJ. PMID: 19908235.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    79. Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. EMBO J. 2010 Apr 07; 29(7):1248-61. Sellier C, Rau F, Liu Y, Tassone F, Hukema RK, Gattoni R, Schneider A, Richard S, Willemsen R, Elliott DJ, Hagerman PJ, Charlet-Berguerand N. PMID: 20186122.
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    80. A novel FMR1 PCR method for the routine detection of low abundance expanded alleles and full mutations in fragile X syndrome. Clin Chem. 2010 Mar; 56(3):399-408. Filipovic-Sadic S, Sah S, Chen L, Krosting J, Sekinger E, Zhang W, Hagerman PJ, Stenzel TT, Hadd AG, Latham GJ, Tassone F. PMID: 20056738.
      View in: PubMed   Mentions: 92     Fields:    Translation:Humans
    81. Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Hum Mol Genet. 2010 Jan 01; 19(1):196-208. Chen Y, Tassone F, Berman RF, Hagerman PJ, Hagerman RJ, Willemsen R, Pessah IN. PMID: 19846466.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    82. The Molecular Biology of FXTAS. . 2010 Jan 1; 77-93. Flora Tassone, Paul J. Hagerman. .
      View in: Publisher Site   Mentions:
    83. Molecular pathogenesis of fragile X-associated tremor/ataxia syndrome. J Investig Med. 2009 Dec; 57(8):825-9. Raske C, Hagerman PJ. PMID: 19794313.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    84. Fibroblast phenotype in male carriers of FMR1 premutation alleles. Hum Mol Genet. 2010 Jan 15; 19(2):299-312. Garcia-Arocena D, Yang JE, Brouwer JR, Tassone F, Iwahashi C, Berry-Kravis EM, Goetz CG, Sumis AM, Zhou L, Nguyen DV, Campos L, Howell E, Ludwig A, Greco C, Willemsen R, Hagerman RJ, Hagerman PJ. PMID: 19864489.
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    85. Functional status of men with the fragile X premutation, with and without the tremor/ataxia syndrome (FXTAS). Int J Geriatr Psychiatry. 2009 Oct; 24(10):1101-9. Brega AG, Reynolds A, Bennett RE, Leehey MA, Bounds LS, Cogswell JB, Hagerman RJ, Hagerman PJ, Grigsby J. PMID: 19404994.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    86. Translation of the FMR1 mRNA is not influenced by AGG interruptions. Nucleic Acids Res. 2009 Nov; 37(20):6896-904. Ludwig AL, Raske C, Tassone F, Garcia-Arocena D, Hershey JW, Hagerman PJ. PMID: 19752155.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    87. Polymerase chain reaction, nuclease digestion, and mass spectrometry based assay for the trinucleotide repeat status of the fragile X mental retardation 1 gene. Anal Chem. 2009 Jul 01; 81(13):5533-40. Dodds ED, Tassone F, Hagerman PJ, Lebrilla CB. PMID: 19514725.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    88. Origins of epilepsy in fragile X syndrome. Epilepsy Curr. 2009 Jul-Aug; 9(4):108-12. Hagerman PJ, Stafstrom CE. PMID: 19693328.
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    89. FMR1 premutation in females diagnosed with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2009 Jul; 80(7):812-4. Zhang L, Coffey S, Lua LL, Greco CM, Schafer JA, Brunberg J, Borodyanskaya M, Agius MA, Apperson M, Leehey M, Tartaglia N, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 19531693.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    90. Expansion of an FMR1 grey-zone allele to a full mutation in two generations. J Mol Diagn. 2009 Jul; 11(4):306-10. Fernandez-Carvajal I, Lopez Posadas B, Pan R, Raske C, Hagerman PJ, Tassone F. PMID: 19525339.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    91. A quantitative ELISA assay for the fragile x mental retardation 1 protein. J Mol Diagn. 2009 Jul; 11(4):281-9. Iwahashi C, Tassone F, Hagerman RJ, Yasui D, Parrott G, Nguyen D, Mayeur G, Hagerman PJ. PMID: 19460937.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    92. Screening for expanded alleles of the FMR1 gene in blood spots from newborn males in a Spanish population. J Mol Diagn. 2009 Jul; 11(4):324-9. Fernandez-Carvajal I, Walichiewicz P, Xiaosen X, Pan R, Hagerman PJ, Tassone F. PMID: 19460941.
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    93. A review of fragile X premutation disorders: expanding the psychiatric perspective. J Clin Psychiatry. 2009 Jun; 70(6):852-62. Bourgeois JA, Coffey SM, Rivera SM, Hessl D, Gane LW, Tassone F, Greco C, Finucane B, Nelson L, Berry-Kravis E, Grigsby J, Hagerman PJ, Hagerman RJ. PMID: 19422761.
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    94. Incomplete financial disclosure in a commentary on testing for fragile X gene mutations throughout the life span. JAMA. 2009 Feb 11; 301(6):601-2. Hagerman PJ. PMID: 19211466.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    95. Screening for the presence of FMR1 premutation alleles in women with parkinsonism. Arch Neurol. 2009 Feb; 66(2):244-9. Cilia R, Kraff J, Canesi M, Pezzoli G, Goldwurm S, Amiri K, Tang HT, Pan R, Hagerman PJ, Tassone F. PMID: 19204162.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    96. Covariate adjusted correlation analysis with application to FMR1 premutation female carrier data. Biometrics. 2009 Sep; 65(3):781-92. Sentürk D, Nguyen DV, Tassone F, Hagerman RJ, Carroll RJ, Hagerman PJ. PMID: 19173699.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    97. Testing for fragile X gene mutations throughout the life span. JAMA. 2008 Nov 26; 300(20):2419-21. Hagerman RJ, Hagerman PJ. PMID: 19033593.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    98. Autism profiles of males with fragile X syndrome. Am J Ment Retard. 2008 Nov; 113(6):427-38. Harris SW, Hessl D, Goodlin-Jones B, Ferranti J, Bacalman S, Barbato I, Tassone F, Hagerman PJ, Herman H, Hagerman RJ. PMID: 19127654.
      View in: PubMed   Mentions: 144     Fields:    Translation:Humans
    99. Core flexibility of a truncated metazoan mitochondrial tRNA. Nucleic Acids Res. 2008 Oct; 36(17):5472-81. Frazer-Abel AA, Hagerman PJ. PMID: 18718926.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    100. Clinical and neuropathologic findings in a woman with the FMR1 premutation and multiple sclerosis. Arch Neurol. 2008 Aug; 65(8):1114-6. Greco CM, Tassone F, Garcia-Arocena D, Tartaglia N, Coffey SM, Vartanian TK, Brunberg JA, Hagerman PJ, Hagerman RJ. PMID: 18695063.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    101. Reduced telomere length in older men with premutation alleles of the fragile X mental retardation 1 gene. Am J Med Genet A. 2008 Jun 15; 146A(12):1543-6. Jenkins EC, Tassone F, Ye L, Gu H, Xi M, Velinov M, Brown WT, Hagerman RJ, Hagerman PJ. PMID: 18478592.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    102. The fragile X prevalence paradox. J Med Genet. 2008 Aug; 45(8):498-9. Hagerman PJ. PMID: 18413371.
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    103. Expanded clinical phenotype of women with the FMR1 premutation. Am J Med Genet A. 2008 Apr 15; 146A(8):1009-16. Coffey SM, Cook K, Tartaglia N, Tassone F, Nguyen DV, Pan R, Bronsky HE, Yuhas J, Borodyanskaya M, Grigsby J, Doerflinger M, Hagerman PJ, Hagerman RJ. PMID: 18348275.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    104. Abnormal nerve conduction features in fragile X premutation carriers. Arch Neurol. 2008 Apr; 65(4):495-8. Soontarapornchai K, Maselli R, Fenton-Farrell G, Tassone F, Hagerman PJ, Hessl D, Hagerman RJ. PMID: 18413472.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    105. A quantitative assessment of tremor and ataxia in FMR1 premutation carriers using CATSYS. Am J Med Genet A. 2008 Mar 01; 146A(5):629-35. Aguilar D, Sigford KE, Soontarapornchai K, Nguyen DV, Adams PE, Yuhas JM, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 18241072.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    106. The primary cognitive deficit among males with fragile X-associated tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome. J Clin Exp Neuropsychol. 2008 Nov; 30(8):853-69. Brega AG, Goodrich G, Bennett RE, Hessl D, Engle K, Leehey MA, Bounds LS, Paulich MJ, Hagerman RJ, Hagerman PJ, Cogswell JB, Tassone F, Reynolds A, Kooken R, Kenny M, Grigsby J. PMID: 18608667.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    107. Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation. Brain Imaging Behav. 2008 Jan 18; 2(2):105-116. Koldewyn K, Hessl D, Adams J, Tassone F, Hagerman PJ, Hagerman RJ, Rivera SM. PMID: 19430586.
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    108. Cognitive profile of fragile X premutation carriers with and without fragile X-associated tremor/ataxia syndrome. Neuropsychology. 2008 Jan; 22(1):48-60. Grigsby J, Brega AG, Engle K, Leehey MA, Hagerman RJ, Tassone F, Hessl D, Hagerman PJ, Cogswell JB, Bennett RE, Cook K, Hall DA, Bounds LS, Paulich MJ, Reynolds A. PMID: 18211155.
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    109. Fragile X-associated tremor/ataxia syndrome: an aging face of the fragile X gene. Arch Neurol. 2008 Jan; 65(1):19-25. Amiri K, Hagerman RJ, Hagerman PJ. PMID: 18195136.
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    110. Treatment of fragile X-associated tremor ataxia syndrome (FXTAS) and related neurological problems. Clin Interv Aging. 2008; 3(2):251-62. Hagerman RJ, Hall DA, Coffey S, Leehey M, Bourgeois J, Gould J, Zhang L, Seritan A, Berry-Kravis E, Olichney J, Miller JW, Fong AL, Carpenter R, Bodine C, Gane LW, Rainin E, Hagerman H, Hagerman PJ. PMID: 18686748.
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    111. Isolation of pathology-associated intranuclear inclusions. Methods Mol Biol. 2008; 463:181-90. Iwahashi C, Hagerman PJ. PMID: 18951169.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    112. A rapid polymerase chain reaction-based screening method for identification of all expanded alleles of the fragile X (FMR1) gene in newborn and high-risk populations. J Mol Diagn. 2008 Jan; 10(1):43-9. Tassone F, Pan R, Amiri K, Taylor AK, Hagerman PJ. PMID: 18165273.
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    113. Age-dependent cognitive changes in carriers of the fragile X syndrome. Cortex. 2008 Jun; 44(6):628-36. Cornish KM, Li L, Kogan CS, Jacquemont S, Turk J, Dalton A, Hagerman RJ, Hagerman PJ. PMID: 18472033.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    114. FMR1 CGG repeat length predicts motor dysfunction in premutation carriers. Neurology. 2008 Apr 15; 70(16 Pt 2):1397-402. Leehey MA, Berry-Kravis E, Goetz CG, Zhang L, Hall DA, Li L, Rice CD, Lara R, Cogswell J, Reynolds A, Gane L, Jacquemont S, Tassone F, Grigsby J, Hagerman RJ, Hagerman PJ. PMID: 18057320.
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    115. Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines. Mov Disord. 2007 Oct 31; 22(14):2018-30, quiz 2140. Berry-Kravis E, Abrams L, Coffey SM, Hall DA, Greco C, Gane LW, Grigsby J, Bourgeois JA, Finucane B, Jacquemont S, Brunberg JA, Zhang L, Lin J, Tassone F, Hagerman PJ, Hagerman RJ, Leehey MA. PMID: 17618523.
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    116. Systematic characterization of high mass accuracy influence on false discovery and probability scoring in peptide mass fingerprinting. Anal Biochem. 2008 Jan 15; 372(2):156-66. Dodds ED, Clowers BH, Hagerman PJ, Lebrilla CB. PMID: 17980142.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    117. Neuropathy as a presenting feature in fragile X-associated tremor/ataxia syndrome. Am J Med Genet A. 2007 Oct 01; 143A(19):2256-60. Hagerman RJ, Coffey SM, Maselli R, Soontarapornchai K, Brunberg JA, Leehey MA, Zhang L, Gane LW, Fenton-Farrell G, Tassone F, Hagerman PJ. PMID: 17726686.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    118. Secondary structure and dynamics of the r(CGG) repeat in the mRNA of the fragile X mental retardation 1 (FMR1) gene. RNA Biol. 2007 Sep; 4(2):93-100. Zumwalt M, Ludwig A, Hagerman PJ, Dieckmann T. PMID: 17962727.
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    119. Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS). Neurology. 2007 Aug 28; 69(9):851-9. Adams JS, Adams PE, Nguyen D, Brunberg JA, Tassone F, Zhang W, Koldewyn K, Rivera SM, Grigsby J, Zhang L, DeCarli C, Hagerman PJ, Hagerman RJ. PMID: 17724287.
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    120. Screen for excess FMR1 premutation alleles among males with parkinsonism. Arch Neurol. 2007 Jul; 64(7):1002-6. Kraff J, Tang HT, Cilia R, Canesi M, Pezzoli G, Goldwurm S, Hagerman PJ, Tassone F. PMID: 17620491.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    121. CGG repeat length correlates with age of onset of motor signs of the fragile X-associated tremor/ataxia syndrome (FXTAS). Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 05; 144B(4):566-9. Tassone F, Adams J, Berry-Kravis EM, Cohen SS, Brusco A, Leehey MA, Li L, Hagerman RJ, Hagerman PJ. PMID: 17427188.
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    122. Impairment of executive cognitive functioning in males with fragile X-associated tremor/ataxia syndrome. Mov Disord. 2007 Apr 15; 22(5):645-50. Grigsby J, Brega AG, Leehey MA, Goodrich GK, Jacquemont S, Loesch DZ, Cogswell JB, Epstein J, Wilson R, Jardini T, Gould E, Bennett RE, Hessl D, Cohen S, Cook K, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 17266074.
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    123. Testicular and pituitary inclusion formation in fragile X associated tremor/ataxia syndrome. J Urol. 2007 Apr; 177(4):1434-7. Greco CM, Soontrapornchai K, Wirojanan J, Gould JE, Hagerman PJ, Hagerman RJ. PMID: 17382748.
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    124. Elevated FMR1 mRNA in premutation carriers is due to increased transcription. RNA. 2007 Apr; 13(4):555-62. Tassone F, Beilina A, Carosi C, Albertosi S, Bagni C, Li L, Glover K, Bentley D, Hagerman PJ. PMID: 17283214.
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    125. Fragile X syndrome vs fragile X-associated tremor/ataxia syndrome. Arch Neurol. 2007 Feb; 64(2):289; author reply 289-90. Leehey MA, Hagerman RJ, Hagerman PJ. PMID: 17296852.
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    126. Fragile X-associated tremor/ataxia syndrome--an older face of the fragile X gene. Nat Clin Pract Neurol. 2007 Feb; 3(2):107-12. Hagerman PJ, Hagerman RJ. PMID: 17279084.
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    127. Progression of tremor and ataxia in male carriers of the FMR1 premutation. Mov Disord. 2007 Jan 15; 22(2):203-6. Leehey MA, Berry-Kravis E, Min SJ, Hall DA, Rice CD, Zhang L, Grigsby J, Greco CM, Reynolds A, Lara R, Cogswell J, Jacquemont S, Hessl DR, Tassone F, Hagerman R, Hagerman PJ. PMID: 17133502.
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    128. Neuropathic features in fragile X premutation carriers. Am J Med Genet A. 2007 Jan 01; 143A(1):19-26. Berry-Kravis E, Goetz CG, Leehey MA, Hagerman RJ, Zhang L, Li L, Nguyen D, Hall DA, Tartaglia N, Cogswell J, Tassone F, Hagerman PJ. PMID: 17152065.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCellsPHPublic Health
    129. Fragile-X syndrome and fragile X-associated tremor/ataxia syndrome: two faces of FMR1. Lancet Neurol. 2007 Jan; 6(1):45-55. Jacquemont S, Hagerman RJ, Hagerman PJ, Leehey MA. PMID: 17166801.
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    130. 11 RNA-based disorders of muscle and brain. . 2007 Jan 1; (Curr. Opin. Neurol.152002):125-133. Paul J. Hagerman. .
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    131. Fragmentation of singly protonated peptides via a combination of infrared and collisional activation. Anal Chem. 2006 Dec 15; 78(24):8506-11. Dodds ED, Hagerman PJ, Lebrilla CB. PMID: 17165846.
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    132. Amygdala dysfunction in men with the fragile X premutation. Brain. 2007 Feb; 130(Pt 2):404-16. Hessl D, Rivera S, Koldewyn K, Cordeiro L, Adams J, Tassone F, Hagerman PJ, Hagerman RJ. PMID: 17166860.
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    133. Molecular and imaging correlates of the fragile X-associated tremor/ataxia syndrome. Neurology. 2006 Oct 24; 67(8):1426-31. Cohen S, Masyn K, Adams J, Hessl D, Rivera S, Tassone F, Brunberg J, DeCarli C, Zhang L, Cogswell J, Loesch D, Leehey M, Grigsby J, Hagerman PJ, Hagerman R. PMID: 17060569.
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    134. Symptomatic treatment in the fragile X-associated tremor/ataxia syndrome. Mov Disord. 2006 Oct; 21(10):1741-4. Hall DA, Berry-Kravis E, Hagerman RJ, Hagerman PJ, Rice CD, Leehey MA. PMID: 16773616.
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    135. Cognitive impairment in a 65-year-old male with the fragile X-associated tremor-ataxia syndrome (FXTAS). Cogn Behav Neurol. 2006 Sep; 19(3):165-71. Grigsby J, Leehey MA, Jacquemont S, Brunberg JA, Hagerman RJ, Wilson R, Epstein JH, Greco CM, Tassone F, Hagerman PJ. PMID: 16957495.
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    136. X inactivation and cellular mosaicism. JAMA. 2006 Aug 23; 296(8):930-1; author reply 931. Hagerman RJ, Hagerman PJ. PMID: 16926349.
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    137. Impairment in the cognitive functioning of men with fragile X-associated tremor/ataxia syndrome (FXTAS). J Neurol Sci. 2006 Oct 25; 248(1-2):227-33. Grigsby J, Brega AG, Jacquemont S, Loesch DZ, Leehey MA, Goodrich GK, Hagerman RJ, Epstein J, Wilson R, Cogswell JB, Jardini T, Tassone F, Hagerman PJ. PMID: 16780889.
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    138. Size bias of fragile X premutation alleles in late-onset movement disorders. J Med Genet. 2006 Oct; 43(10):804-9. Jacquemont S, Leehey MA, Hagerman RJ, Beckett LA, Hagerman PJ. PMID: 16723388.
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    139. Enhanced peptide mass fingerprinting through high mass accuracy: Exclusion of non-peptide signals based on residual mass. J Proteome Res. 2006 May; 5(5):1195-203. Dodds ED, An HJ, Hagerman PJ, Lebrilla CB. PMID: 16674109.
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    140. Autism spectrum disorders and attention-deficit/hyperactivity disorder in boys with the fragile X premutation. J Dev Behav Pediatr. 2006 Apr; 27(2 Suppl):S137-44. Farzin F, Perry H, Hessl D, Loesch D, Cohen J, Bacalman S, Gane L, Tassone F, Hagerman P, Hagerman R. PMID: 16685180.
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    141. Prevalence of FMR1 repeat expansions in movement disorders. A systematic review. Neuroepidemiology. 2006; 26(3):151-5. Hall DA, Hagerman RJ, Hagerman PJ, Jacquemont S, Leehey MA. PMID: 16493202.
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    142. Chapter 10 Fragile X Syndrome and Fragile X-Associated Tremor/Ataxia Syndrome. . 2006 Jan 1; (Am. J. Med. Genet.841999):165-174. Randi J. Hagerman, Paul J. Hagerman. .
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    143. Dementia with mood symptoms in a fragile X premutation carrier with the fragile X-associated tremor/ataxia syndrome: clinical intervention with donepezil and venlafaxine. J Neuropsychiatry Clin Neurosci. 2006; 18(2):171-7. Bourgeois JA, Farzin F, Brunberg JA, Tassone F, Hagerman P, Zhang L, Hessl D, Hagerman R. PMID: 16720793.
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    144. Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain. 2006 Jan; 129(Pt 1):243-55. Greco CM, Berman RF, Martin RM, Tassone F, Schwartz PH, Chang A, Trapp BD, Iwahashi C, Brunberg J, Grigsby J, Hessl D, Becker EJ, Papazian J, Leehey MA, Hagerman RJ, Hagerman PJ. PMID: 16332642.
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    145. Abnormal elevation of FMR1 mRNA is associated with psychological symptoms in individuals with the fragile X premutation. Am J Med Genet B Neuropsychiatr Genet. 2005 Nov 05; 139B(1):115-21. Hessl D, Tassone F, Loesch DZ, Berry-Kravis E, Leehey MA, Gane LW, Barbato I, Rice C, Gould E, Hall DA, Grigsby J, Wegelin JA, Harris S, Lewin F, Weinberg D, Hagerman PJ, Hagerman RJ. PMID: 16184602.
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    146. An enhanced polymerase chain reaction assay to detect pre- and full mutation alleles of the fragile X mental retardation 1 gene. J Mol Diagn. 2005 Nov; 7(5):605-12. Saluto A, Brussino A, Tassone F, Arduino C, Cagnoli C, Pappi P, Hagerman P, Migone N, Brusco A. PMID: 16258159.
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    147. Protein composition of the intranuclear inclusions of FXTAS. Brain. 2006 Jan; 129(Pt 1):256-71. Iwahashi CK, Yasui DH, An HJ, Greco CM, Tassone F, Nannen K, Babineau B, Lebrilla CB, Hagerman RJ, Hagerman PJ. PMID: 16246864.
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    148. Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells. Hum Mol Genet. 2005 Dec 01; 14(23):3661-71. Arocena DG, Iwahashi CK, Won N, Beilina A, Ludwig AL, Tassone F, Schwartz PH, Hagerman PJ. PMID: 16239243.
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    149. Recent advances in fragile X: a model for autism and neurodegeneration. Curr Opin Psychiatry. 2005 Sep; 18(5):490-6. Hagerman RJ, Ono MY, Hagerman PJ. PMID: 16639106.
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    150. Initial diagnoses given to persons with the fragile X associated tremor/ataxia syndrome (FXTAS). Neurology. 2005 Jul 26; 65(2):299-301. Hall DA, Berry-Kravis E, Jacquemont S, Rice CD, Cogswell J, Zhang L, Hagerman RJ, Hagerman PJ, Leehey MA. PMID: 16043804.
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    151. Spastic paraparesis, cerebellar ataxia, and intention tremor: a severe variant of FXTAS? J Med Genet. 2005 Feb; 42(2):e14. Jacquemont S, Orrico A, Galli L, Sahota PK, Brunberg JA, Anichini C, Leehey M, Schaeffer S, Hagerman RJ, Hagerman PJ, Tassone F. PMID: 15689437.
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    152. Neural progenitor cells from an adult patient with fragile X syndrome. BMC Med Genet. 2005 Jan 14; 6:2. Schwartz PH, Tassone F, Greco CM, Nethercott HE, Ziaeian B, Hagerman RJ, Hagerman PJ. PMID: 15649335.
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    153. Variation of the acceptor-anticodon interstem angles among mitochondrial and non-mitochondrial tRNAs. J Mol Biol. 2004 Oct 15; 343(2):313-25. Frazer-Abel AA, Hagerman PJ. PMID: 15451663.
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    154. The effect of pre-mutation of X chromosome CGG trinucleotide repeats on brain anatomy. Brain. 2004 Dec; 127(Pt 12):2672-81. Moore CJ, Daly EM, Tassone F, Tysoe C, Schmitz N, Ng V, Chitnis X, McGuire P, Suckling J, Davies KE, Hagerman RJ, Hagerman PJ, Murphy KC, Murphy DG. PMID: 15483045.
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    155. Origin of the intrinsic rigidity of DNA. Nucleic Acids Res. 2004; 32(13):4055-9. Mills JB, Hagerman PJ. PMID: 15289578.
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    156. Screen for expanded FMR1 alleles in patients with essential tremor. Mov Disord. 2004 Aug; 19(8):930-3. Garcia Arocena D, Louis ED, Tassone F, Gilliam TC, Ottman R, Jacquemont S, Hagerman PJ. PMID: 15300658.
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    157. FMR1 RNA within the intranuclear inclusions of fragile X-associated tremor/ataxia syndrome (FXTAS). RNA Biol. 2004 Jul; 1(2):103-5. Tassone F, Iwahashi C, Hagerman PJ. PMID: 17179750.
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    158. Genetic counseling for families of patients with fragile X syndrome. JAMA. 2004 Jun 23; 291(24):2945; author reply 2945-6. Barrett SK, Drazin T, Rosa D, Kupchik GS. PMID: 15213204.
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    159. Fragile-X-associated tremor/ataxia syndrome (FXTAS) in females with the FMR1 premutation. Am J Hum Genet. 2004 May; 74(5):1051-6. Hagerman RJ, Leavitt BR, Farzin F, Jacquemont S, Greco CM, Brunberg JA, Tassone F, Hessl D, Harris SW, Zhang L, Jardini T, Gane LW, Ferranti J, Ruiz L, Leehey MA, Grigsby J, Hagerman PJ. PMID: 15065016.
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    160. Intranuclear inclusions in neural cells with premutation alleles in fragile X associated tremor/ataxia syndrome. J Med Genet. 2004 Apr; 41(4):e43. Tassone F, Hagerman RJ, Garcia-Arocena D, Khandjian EW, Greco CM, Hagerman PJ. PMID: 15060119.
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    161. The fragile-X premutation: a maturing perspective. Am J Hum Genet. 2004 May; 74(5):805-16. Hagerman PJ, Hagerman RJ. PMID: 15052536.
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    162. Aging in individuals with the FMR1 mutation. Am J Ment Retard. 2004 Mar; 109(2):154-64. Jacquemont S, Farzin F, Hall D, Leehey M, Tassone F, Gane L, Zhang L, Grigsby J, Jardini T, Lewin F, Berry-Kravis E, Hagerman PJ, Hagerman RJ. PMID: 15000674.
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    163. Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population. JAMA. 2004 Jan 28; 291(4):460-9. Jacquemont S, Hagerman RJ, Leehey MA, Hall DA, Levine RA, Brunberg JA, Zhang L, Jardini T, Gane LW, Harris SW, Herman K, Grigsby J, Greco CM, Berry-Kravis E, Tassone F, Hagerman PJ. PMID: 14747503.
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    164. Redistribution of transcription start sites within the FMR1 promoter region with expansion of the downstream CGG-repeat element. Hum Mol Genet. 2004 Mar 01; 13(5):543-9. Beilina A, Tassone F, Schwartz PH, Sahota P, Hagerman PJ. PMID: 14722156.
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    165. Fragile X-associated tremor/ataxia syndrome (FXTAS). Ment Retard Dev Disabil Res Rev. 2004; 10(1):25-30. Hagerman PJ, Hagerman RJ. PMID: 14994285.
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    166. A neuropsychological investigation of male premutation carriers of fragile X syndrome. Neuropsychologia. 2004; 42(14):1934-47. Moore CJ, Daly EM, Schmitz N, Tassone F, Tysoe C, Hagerman RJ, Hagerman PJ, Morris RG, Murphy KC, Murphy DG. PMID: 15381024.
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    167. The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter. Hum Mol Genet. 2003 Dec 01; 12(23):3067-74. Chen LS, Tassone F, Sahota P, Hagerman PJ. PMID: 14519687.
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    168. Transformation and normalization of oligonucleotide microarray data. Bioinformatics. 2003 Sep 22; 19(14):1817-23. Geller SC, Gregg JP, Hagerman P, Rocke DM. PMID: 14512353.
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    169. Distribution of CGG repeat sizes within the fragile X mental retardation 1 (FMR1) homologue in a non-human primate population. Hum Genet. 2003 Oct; 113(5):371-6. Garcia Arocena D, Breece KE, Hagerman PJ. PMID: 12905066.
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    170. The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome. Hum Mol Genet. 2003 May 01; 12(9):949-59. Willemsen R, Hoogeveen-Westerveld M, Reis S, Holstege J, Severijnen LA, Nieuwenhuizen IM, Schrier M, van Unen L, Tassone F, Hoogeveen AT, Hagerman PJ, Mientjes EJ, Oostra BA. PMID: 12700164.
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    171. Tremor and ataxia in fragile X premutation carriers: blinded videotape study. Ann Neurol. 2003 May; 53(5):616-23. Berry-Kravis E, Lewin F, Wuu J, Leehey M, Hagerman R, Hagerman P, Goetz CG. PMID: 12730995.
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    172. Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet. 2003 Apr; 72(4):869-78. Jacquemont S, Hagerman RJ, Leehey M, Grigsby J, Zhang L, Brunberg JA, Greco C, Des Portes V, Jardini T, Levine R, Berry-Kravis E, Brown WT, Schaeffer S, Kissel J, Tassone F, Hagerman PJ. PMID: 12638084.
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    173. The fragile X premutation presenting as essential tremor. Arch Neurol. 2003 Jan; 60(1):117-21. Leehey MA, Munhoz RP, Lang AE, Brunberg JA, Grigsby J, Greco C, Jacquemont S, Tassone F, Lozano AM, Hagerman PJ, Hagerman RJ. PMID: 12533098.
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    174. A cerebellar tremor/ataxia syndrome among fragile X premutation carriers. Cytogenet Genome Res. 2003; 100(1-4):206-12. Hagerman PJ, Greco CM, Hagerman RJ. PMID: 14526182.
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    175. Expression of the FMR1 gene. Cytogenet Genome Res. 2003; 100(1-4):124-8. Tassone F, Hagerman PJ. PMID: 14526172.
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    176. Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations. RNA. 2002 Dec; 8(12):1482-8. Primerano B, Tassone F, Hagerman RJ, Hagerman P, Amaldi F, Bagni C. PMID: 12515381.
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    177. Fragile X premutation carriers: characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction. AJNR Am J Neuroradiol. 2002 Nov-Dec; 23(10):1757-66. Brunberg JA, Jacquemont S, Hagerman RJ, Berry-Kravis EM, Grigsby J, Leehey MA, Tassone F, Brown WT, Greco CM, Hagerman PJ. PMID: 12427636.
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    178. Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers. Brain. 2002 Aug; 125(Pt 8):1760-71. Greco CM, Hagerman RJ, Tassone F, Chudley AE, Del Bigio MR, Jacquemont S, Leehey M, Hagerman PJ. PMID: 12135967.
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    179. The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region. J Mol Evol. 2002 Jul; 55(1):1-13. van Oppen MJ, Catmull J, McDonald BJ, Hislop NR, Hagerman PJ, Miller DJ. PMID: 12165838.
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    180. Tremor/Ataxia syndrome in fragile X carrier males. Movement Disorders. 2002 Jul 1; 17(4):744-745. Maureen A. Leehey, Randi J. Hagerman, William M. Landau, Jim Grigsby, Flora Tassone, Paul J. Hagerman. .
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    181. The fragile X premutation: into the phenotypic fold. Curr Opin Genet Dev. 2002 Jun; 12(3):278-83. Hagerman RJ, Hagerman PJ. PMID: 12076670.
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    182. Fragile X syndrome: a model of gene-brain-behavior relationships. Mol Genet Metab. 2001 Sep-Oct; 74(1-2):89-97. Hagerman RJ, Hagerman PJ. PMID: 11592806.
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    183. The 5'-untranslated region of the FMR1 message facilitates translation by internal ribosome entry. J Biol Chem. 2001 Oct 12; 276(41):37916-21. Chiang PW, Carpenter LE, Hagerman PJ. PMID: 11489899.
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    184. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology. 2001 Jul 10; 57(1):127-30. Hagerman RJ, Leehey M, Heinrichs W, Tassone F, Wilson R, Hills J, Grigsby J, Gage B, Hagerman PJ. PMID: 11445641.
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    185. A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA. J Med Genet. 2001 Jul; 38(7):453-6. Tassone F, Hagerman RJ, Taylor AK, Hagerman PJ. PMID: 11432964.
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    186. Structural studies of the tRNA domain of tmRNA. J Mol Biol. 2001 Jun 08; 309(3):727-35. Stagg SM, Frazer-Abel AA, Hagerman PJ, Harvey SC. PMID: 11397092.
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    187. Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA. Am J Med Genet. 2000 Sep 18; 94(3):232-6. Tassone F, Hagerman RJ, Loesch DZ, Lachiewicz A, Taylor AK, Hagerman PJ. PMID: 10995510.
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    188. Nucleic acids Theory and experiment. Current Opinion in Structural Biology. 2000 Jun 1; 10(3):275-278. Paul J Hagerman, Ignacio Tinoco. .
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    189. Clinical involvement and protein expression in individuals with the FMR1 premutation. Am J Med Genet. 2000 Mar 13; 91(2):144-52. Tassone F, Hagerman RJ, Taylor AK, Mills JB, Harris SW, Gane LW, Hagerman PJ. PMID: 10748416.
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    190. Transient electric birefringence for determining global conformations of nonhelix elements and protein-induced bends in RNA. Methods Enzymol. 2000; 317:440-53. Hagerman PJ. PMID: 10829294.
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    191. Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in the fragile-X syndrome. Am J Hum Genet. 2000 Jan; 66(1):6-15. Tassone F, Hagerman RJ, Taylor AK, Gane LW, Godfrey TE, Hagerman PJ. PMID: 10631132.
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    192. Transcription of the FMR1 gene in individuals with fragile X syndrome. Am J Med Genet. 2000; 97(3):195-203. Tassone F, Hagerman RJ, Chamberlain WD, Hagerman PJ. PMID: 11449488.
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    193. Gene content and organization in a segment of the mitochondrial genome of the scleractinian coral Acropora tenuis: major differences in gene order within the anthozoan subclass zoantharia. Mol Biol Evol. 1999 Dec; 16(12):1812-5. van Oppen MJ, Hislop NR, Hagerman PJ, Miller DJ. PMID: 10605123.
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    194. Determination of the angle between the acceptor and anticodon stems of a truncated mitochondrial tRNA. J Mol Biol. 1999 Jan 15; 285(2):581-93. Frazer-Abel AA, Hagerman PJ. PMID: 9878431.
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    195. Flexibility of single-stranded DNA: use of gapped duplex helices to determine the persistence lengths of poly(dT) and poly(dA). J Mol Biol. 1999 Jan 08; 285(1):245-57. Mills JB, Vacano E, Hagerman PJ. PMID: 9878403.
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    196. Global flexibility of tertiary structure in RNA: yeast tRNAPhe as a model system. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3572-7. Friederich MW, Vacano E, Hagerman PJ. PMID: 9520407.
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    197. Protein and Mg(2+)-induced conformational changes in the S15 binding site of 16 S ribosomal RNA. J Mol Biol. 1998 Jan 23; 275(3):453-64. Orr JW, Hagerman PJ, Williamson JR. PMID: 9466923.
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    198. Analysis of birefringence decay profiles for nucleic acid helices possessing bends: the tau-ratio approach. Biophys J. 1997 Jul; 73(1):306-17. Vacano E, Hagerman PJ. PMID: 9199795.
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    199. Influence of static and dynamic bends on the birefringence decay profile of RNA helices: Brownian dynamics simulations. Biophys J. 1997 Jul; 73(1):318-32. Zacharias M, Hagerman PJ. PMID: 9199796.
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    200. The angle between the anticodon and aminoacyl acceptor stems of yeast tRNA(Phe) is strongly modulated by magnesium ions. Biochemistry. 1997 May 20; 36(20):6090-9. Friederich MW, Hagerman PJ. PMID: 9166779.
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    201. Flexibility of RNA. Annu Rev Biophys Biomol Struct. 1997; 26:139-56. Hagerman PJ. PMID: 9241416.
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    202. Sometimes a great motion: the application of transient electric birefringence to the study of macromolecular structure. Curr Opin Struct Biol. 1996 Oct; 6(5):643-9. Hagerman PJ. PMID: 8913687.
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    203. Do basic region-leucine zipper proteins bend their DNA targets ... does it matter? Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):9993-6. Hagerman PJ. PMID: 8816735.
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    204. The global conformation of an active hammerhead RNA during the process of self-cleavage. J Mol Biol. 1996 Aug 16; 261(2):125-34. Amiri KM, Hagerman PJ. PMID: 8757281.
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    205. Helix rigidity of DNA: the meroduplex as an experimental paradigm. J Mol Biol. 1996 Jul 12; 260(2):207-23. Hagerman KR, Hagerman PJ. PMID: 8764401.
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    206. Hammering away at RNA global structure. Curr Opin Struct Biol. 1996 Jun; 6(3):317-21. Hagerman PJ, Amiri KM. PMID: 8804834.
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    207. From sequence to structure to function. Curr Opin Struct Biol. 1996 06 01; 6(3):277-80. Hagerman PJ, Tinoco I. PMID: 8805487.
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    208. The influence of symmetric internal loops on the flexibility of RNA. J Mol Biol. 1996 Mar 29; 257(2):276-89. Zacharias M, Hagerman PJ. PMID: 8609623.
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    209. A noncanonical tertiary conformation of a human mitochondrial transfer RNA. Biochemistry. 1995 Dec 19; 34(50):16235-9. Leehey MA, Squassoni CA, Friederich MW, Mills JB, Hagerman PJ. PMID: 8845346.
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    210. A nomenclature of junctions and branchpoints in nucleic acids. Nucleic Acids Res. 1995 Sep 11; 23(17):3363-4. Lilley DM, Clegg RM, Diekmann S, Seeman NC, Von Kitzing E, Hagerman PJ. PMID: 16617514.
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    211. The bend in RNA created by the trans-activation response element bulge of human immunodeficiency virus is straightened by arginine and by Tat-derived peptide. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):6052-6. Zacharias M, Hagerman PJ. PMID: 7597079.
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    212. Determination of the angle between the anticodon and aminoacyl acceptor stems of yeast phenylalanyl tRNA in solution. Proc Natl Acad Sci U S A. 1995 May 23; 92(11):4803-7. Friederich MW, Gast FU, Vacano E, Hagerman PJ. PMID: 7761403.
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    213. Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB). A nomenclature of junctions and branchpoints in nucleic acids. Recommendations 1994. Eur J Biochem. 1995 May 15; 230(1):1-2. Lilley DM, Clegg RM, Diekmann S, Seeman NC, von Kitzing E, Hagerman P. PMID: 7601087.
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    214. Persistence length of RNA. Biochemistry. 1995 Apr 04; 34(13):4354-7. Kebbekus P, Draper DE, Hagerman P. PMID: 7535562.
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    215. Bulge-induced bends in RNA: quantification by transient electric birefringence. J Mol Biol. 1995 Mar 31; 247(3):486-500. Zacharias M, Hagerman PJ. PMID: 7536250.
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    216. Investigation of the influence of cytosine methylation on DNA flexibility. J Biol Chem. 1995 Jan 06; 270(1):197-201. Hodges-Garcia Y, Hagerman PJ. PMID: 7814373.
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    217. Global conformation of a self-cleaving hammerhead RNA. Biochemistry. 1994 Nov 15; 33(45):13172-7. Amiri KM, Hagerman PJ. PMID: 7947724.
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    218. Excess counterion accumulation around branched nucleic acids. J Mol Biol. 1994 Nov 11; 243(5):919-29. Olmsted MC, Hagerman PJ. PMID: 7525974.
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    219. Conformation of the central, three-helix junction of the 5 S ribosomal RNA of Sulfolobus acidocaldarius. J Mol Biol. 1994 Aug 19; 241(3):415-30. Shen Z, Hagerman PJ. PMID: 7520504.
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    220. Electrophoretic evidence that single-stranded regions of one or more nucleotides dramatically increase the flexibility of DNA. Biochemistry. 1994 Feb 22; 33(7):1797-803. Mills JB, Cooper JP, Hagerman PJ. PMID: 8110781.
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    221. Interhelix geometry of stems I and II of a self-cleaving hammerhead RNA. Biochemistry. 1994 Feb 22; 33(7):1788-96. Gast FU, Amiri KM, Hagerman PJ. PMID: 7509191.
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    222. Cytosine methylation can induce local distortions in the structure of duplex DNA. Biochemistry. 1992 Aug 25; 31(33):7595-9. Hodges-Garcia Y, Hagerman PJ. PMID: 1510946.
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    223. Straightening out the bends in curved DNA. Biochim Biophys Acta. 1992 Jun 15; 1131(2):125-32. Hagerman PJ. PMID: 1610891.
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    224. Structures of branched DNA molecules in solution. Current Opinion in Structural Biology. 1991 Jun 1; 1(3):464-468. Julia P. Cooper, Paul J. Hagerman. .
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    225. Electrophoretic and hydrodynamic properties of duplex ribonucleic acid molecules transcribed in vitro: evidence that A-tracts do not generate curvature in RNA. Biochemistry. 1991 Apr 30; 30(17):4268-77. Gast FU, Hagerman PJ. PMID: 2021619.
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    226. RNA 'tetraloops': living in syn. Curr Biol. 1991 Feb; 1(1):50-2. Hagerman PJ. PMID: 15336208.
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    227. DNA typing in the forensic arena. Am J Hum Genet. 1990 Nov; 47(5):876-7. Hagerman PJ. PMID: 2278587.
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    228. Analysis of fluorescence energy transfer in duplex and branched DNA molecules. Biochemistry. 1990 Oct 02; 29(39):9261-8. Cooper JP, Hagerman PJ. PMID: 2271593.
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    229. Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. I. Computational analysis. J Mol Biol. 1990 Mar 20; 212(2):351-62. Hagerman PJ, Ramadevi VA. PMID: 2319603.
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    230. Application of the method of phage T4 DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat. J Mol Biol. 1990 Mar 20; 212(2):363-76. Taylor WH, Hagerman PJ. PMID: 2319604.
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    231. Pyrimidine 5-methyl groups influence the magnitude of DNA curvature. Biochemistry. 1990 Feb 27; 29(8):1980-3. Hagerman PJ. PMID: 2328230.
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    232. Sequence-directed curvature of DNA. Annu Rev Biochem. 1990; 59:755-81. Hagerman PJ. PMID: 2197990.
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    233. Geometry of a branched DNA structure in solution. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7336-40. Cooper JP, Hagerman PJ. PMID: 2798413.
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    234. DNA ring closure mediated by protein HU. J Biol Chem. 1989 Sep 05; 264(25):14621-3. Hodges-Garcia Y, Hagerman PJ, Pettijohn DE. PMID: 2768236.
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    235. Flexibility of DNA. Annu Rev Biophys Biophys Chem. 1988; 17:265-86. Hagerman PJ. PMID: 3293588.
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    236. Gel electrophoretic analysis of the geometry of a DNA four-way junction. J Mol Biol. 1987 Dec 20; 198(4):711-9. Cooper JP, Hagerman PJ. PMID: 2828644.
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    237. A general method for cloning DNA fragments in multiple copies. Gene. 1987; 53(2-3):139-44. Taylor WH, Hagerman PJ. PMID: 3609745.
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    238. Sequence-directed curvature of DNA. Nature. 1986 May 22-28; 321(6068):449-50. Hagerman PJ. PMID: 3713816.
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    239. Sequence dependence of the curvature of DNA: a test of the phasing hypothesis. Biochemistry. 1985 Dec 03; 24(25):7033-7. Hagerman PJ. PMID: 4084556.
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    240. Analysis of the ring-closure probabilities of isotropic wormlike chains: application to duplex DNA. Biopolymers. 1985 Oct; 24(10):1881-97. Hagerman PJ. PMID: 4074845.
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    241. Application of transient electric birefringence to the study of biopolymer structure. Methods Enzymol. 1985; 117:198-219. Hagerman PJ. PMID: 3001479.
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    242. Interstrand psoralen cross-links do not introduce appreciable bends in DNA. Biochemistry. 1984 Dec 18; 23(26):6299-303. Sinden RR, Hagerman PJ. PMID: 6529552.
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    243. The relationship between uracil incorporation into DNA and the expression of fragile sites in human. Am J Med Genet. 1984 Oct; 19(2):407-9. Hagerman PJ. PMID: 6507488.
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    244. Evidence for the existence of stable curvature of DNA in solution. Proc Natl Acad Sci U S A. 1984 Aug; 81(15):4632-6. Hagerman PJ. PMID: 6087336.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    245. The fragile X syndrome: history, diagnosis, and treatment. J Dev Behav Pediatr. 1983 Jun; 4(2):122-30. Hagerman RJ, McBogg P, Hagerman PJ. PMID: 6348096.
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    246. Electrostatic contribution to the stiffness of DNA molecules of finite length. Biopolymers. 1983 Mar; 22(3):811-4. Hagerman PJ. PMID: 6850051.
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    247. Investigation of the flexibility of DNA using transient electric birefringence. Biopolymers. 1981 Jul; 20(7):1503-35. Hagerman PJ. PMID: 7023566.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    248. Monte Carlo approach to the analysis of the rotational diffusion of wormlike chains. Biopolymers. 1981 Jul 1; 20(7):1481-1502. Paul J. Hagerman, Bruno H. Zimm. .
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    249. Refolding behavior of a kinetic intermediate observed in the low pH unfolding of ribonuclease A. Biochemistry. 1979 Jan 23; 18(2):293-7. Hagerman PJ, Schmid FX, Baldwin RL. PMID: 33695.
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    250. Kinetic analysis of the reversible folding reactions of small proteins: application to the folding of lysozyme and cytochrome c. Biopolymers. 1977 Apr; 16(4):731-47. Hagerman PJ. PMID: 192357.
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    251. A quantitative treatment of the kinetics of the folding transition of ribonuclease A. Biochemistry. 1976 Apr 06; 15(7):1462-73. Hagerman PJ, Baldwin RL. PMID: 4087.
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