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Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial. JAMA Neurol. 2023 11 01; 80(11):1145-1154.
French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Pimstone S, Aycardi E, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN, X-TOLE Study Group. PMID: 37812429; PMCID: PMC10562989.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs. Epilepsia Open. 2023 06; 8(2):666-672.
Bruun DA, Ma B, Chen YJ, Wu CY, Aleman M, Zolkowska D, Smiley-Jewell SM, Rogawski MA, Lein PJ. PMID: 36919379; PMCID: PMC10235566.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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A randomized, open-label, two-treatment crossover study to evaluate the effect of food on the pharmacokinetics of diazepam nasal spray in healthy adults. Epilepsia. 2023 02; 64(2):364-373.
Rogawski MA, Slatko G. PMID: 36413125; PMCID: PMC10107174.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs. J Pharmacol Exp Ther. 2022 02; 380(2):104-113.
Vuu I, Patterson EE, Wu CY, Zolkowska D, Leppik IE, Rogawski MA, Worrell GA, Kremen V, Cloyd JC, Coles LD. PMID: 34862270; PMCID: PMC11048262.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus. Neurotoxicology. 2021 12; 87:43-50.
Calsbeek JJ, González EA, Boosalis CA, Zolkowska D, Bruun DA, Rowland DJ, Saito NH, Harvey DJ, Chaudhari AJ, Rogawski MA, Garbow JR, Lein PJ. PMID: 34478772; PMCID: PMC8595842.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Cortical excitability threshold can be increased by the AMPA blocker Perampanel in amyotrophic lateral sclerosis. Muscle Nerve. 2021 08; 64(2):215-219.
Oskarsson B, Mauricio EA, Shah JS, Li Z, Rogawski MA. PMID: 34008857.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam. Arch Toxicol. 2021 07; 95(7):2459-2468.
Zolkowska D, Dhir A, Rogawski MA. PMID: 33914090; PMCID: PMC8241714.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Intranasal Allopregnanolone Confers Rapid Seizure Protection: Evidence for Direct Nose-to-Brain Delivery. Neurotherapeutics. 2021 01; 18(1):544-555.
Zolkowska D, Wu CY, Rogawski MA. PMID: 33405197; PMCID: PMC8116426.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Safety, tolerability, and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: A single and multiple ascending dose phase 1b/2a clinical trial. Alzheimers Dement (N Y). 2020; 6(1):e12107.
Hernandez GD, Solinsky CM, Mack WJ, Kono N, Rodgers KE, Wu CY, Mollo AR, Lopez CM, Pawluczyk S, Bauer G, Matthews D, Shi Y, Law M, Rogawski MA, Schneider LS, Brinton RD. PMID: 33344752; PMCID: PMC7744018.
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PubMed Mentions:
10
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Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Ann N Y Acad Sci. 2020 11; 1480(1):183-206.
Dhir A, Bruun DA, Guignet M, Tsai YH, González E, Calsbeek J, Vu J, Saito N, Tancredi DJ, Harvey DJ, Lein PJ, Rogawski MA. PMID: 32915470; PMCID: PMC7756871.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Arch Toxicol. 2020 06; 94(6):2149-2162.
González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. PMID: 32303805; PMCID: PMC7305973.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects. Epilepsy Curr. 2020 Jan-Feb; 20(1_suppl):23S-30S.
Traynelis SF, Dlugos D, Henshall D, Mefford HC, Rogawski MA, Staley KJ, Dacks PA, Whittemore V, Poduri A, National Institutes of Neurological Disorders and Stroke (NINDS)/American Epilepsy Society (AES) Epi. PMID: 31965829; PMCID: PMC7031805.
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PubMed Mentions:
5
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Mechanisms of action of currently used antiseizure drugs. Neuropharmacology. 2020 05 15; 168:107966.
Sills GJ, Rogawski MA. PMID: 32120063.
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PubMed Mentions:
166 Fields:
Translation:
HumansAnimals
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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction. Sci Transl Med. 2019 12 04; 11(521).
Senatorov VV, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H, Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A, Friedman A, Kaufer D. PMID: 31801886.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Diazepam buccal film for the treatment of acute seizures. Epilepsy Behav. 2019 12; 101(Pt B):106537.
Rogawski MA, Heller AH. PMID: 31699662.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Reduced efficacy and risk of seizure aggravation when cannabidiol is used without clobazam. Epilepsy Behav. 2020 02; 103(Pt A):106506.
Rogawski MA. PMID: 31526646.
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PubMed Mentions:
4 Fields:
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Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiol Dis. 2020 01; 133:104431.
Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. PMID: 30905768; PMCID: PMC6754818.
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PubMed Mentions:
49 Fields:
Translation:
Animals
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Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study. Mol Neurobiol. 2019 May; 56(5):3702-3713.
Napoli E, Schneider A, Wang JY, Trivedi A, Carrillo NR, Tassone F, Rogawski M, Hagerman RJ, Giulivi C. PMID: 30187385; PMCID: PMC6401336.
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PubMed Mentions:
20 Fields:
Translation:
HumansCellsCTClinical Trials
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Determination of minimal steady-state plasma level of diazepam causing seizure threshold elevation in rats. Epilepsia. 2018 05; 59(5):935-944.
Dhir A, Rogawski MA. PMID: 29682729; PMCID: PMC5934328.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment-resistant status epilepticus. Epilepsia. 2018 10; 59 Suppl 2:220-227.
Zolkowska D, Wu CY, Rogawski MA. PMID: 29453777; PMCID: PMC6910080.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia. 2018 01; 59(1):37-66.
Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W. PMID: 29247482; PMCID: PMC5993212.
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PubMed Mentions:
131 Fields:
Translation:
HumansAnimals
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Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome. Neurotherapeutics. 2017 Oct; 14(4):1073-1083.
Wang JY, Trivedi AM, Carrillo NR, Yang J, Schneider A, Giulivi C, Adams P, Tassone F, Kim K, Rivera SM, Lubarr N, Wu CY, Irwin RW, Brinton RD, Olichney JM, Rogawski MA, Hagerman RJ. PMID: 28707277; PMCID: PMC5722761.
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PubMed Mentions:
26 Fields:
Translation:
HumansCTClinical Trials
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Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. Neurobiol Dis. 2018 Jan; 109(Pt A):25-32.
Chen CY, Di Lucente J, Lin YC, Lien CC, Rogawski MA, Maezawa I, Jin LW. PMID: 28927958; PMCID: PMC5696074.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Sci Data. 2017 05 09; 4:170061.
Dingledine R, Coulter DA, Fritsch B, Gorter JA, Lelutiu N, McNamara J, Nadler JV, Pitkänen A, Rogawski MA, Skene P, Sloviter RS, Wang Y, Wadman WJ, Wasterlain C, Roopra A. PMID: 28485718; PMCID: PMC5423390.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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First-in-man allopregnanolone use in super-refractory status epilepticus. Ann Clin Transl Neurol. 2017 06; 4(6):411-414.
Vaitkevicius H, Husain AM, Rosenthal ES, Rosand J, Bobb W, Reddy K, Rogawski MA, Cole AJ. PMID: 28589168; PMCID: PMC5454395.
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PubMed Mentions:
20 Fields:
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Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Mol Pharmacol. 2017 07; 92(1):88-99.
Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. PMID: 28428226; PMCID: PMC5452057.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Allopregnanolone decreases interictal spiking and fast ripples in an animal model of mesial temporal lobe epilepsy. Neuropharmacology. 2017 Jul 15; 121:12-19.
Lévesque M, Herrington R, Leclerc L, Rogawski MA, Avoli M. PMID: 28416442.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model. Neuropharmacology. 2017 04; 116:142-150.
Ciarlone SL, Wang X, Rogawski MA, Weeber EJ. PMID: 27986596.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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A New SV2A Ligand for Epilepsy. Cell. 2016 Oct 20; 167(3):587.
Rogawski MA. PMID: 27768878.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136.
Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. PMID: 27467073; PMCID: PMC5063690.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
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Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet. Cold Spring Harb Perspect Med. 2016 05 02; 6(5).
Rogawski MA, Löscher W, Rho JM. PMID: 26801895; PMCID: PMC4852797.
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PubMed Mentions:
104 Fields:
Translation:
HumansAnimals
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A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors. Brain. 2016 Feb; 139(Pt 2):306-9.
Rogawski MA. PMID: 26912516.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Is a separate monotherapy indication warranted for antiepileptic drugs? Lancet Neurol. 2015 Dec; 14(12):1229-40.
Mintzer S, French JA, Perucca E, Cramer JA, Messenheimer JA, Blum DE, Rogawski MA, Baulac M. PMID: 26581972.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1 β3 γ2L GABAA receptor account for their in vivo effects. J Physiol. 2015 Nov 15; 593(22):4943-61.
Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW. PMID: 26378885; PMCID: PMC4650410.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism. Psychopharmacology (Berl). 2016 Jan; 233(2):309-23.
Kazdoba TM, Hagerman RJ, Zolkowska D, Rogawski MA, Crawley JN. PMID: 26525567; PMCID: PMC4703522.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. PLoS One. 2015; 10(6):e0128313.
Irwin RW, Solinsky CM, Loya CM, Salituro FG, Rodgers KE, Bauer G, Rogawski MA, Brinton RD. PMID: 26039057; PMCID: PMC4454520.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42.
Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. PMID: 25882826; PMCID: PMC4466064.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics. 2015 Jan; 12(1):234-49.
Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. PMID: 25256961; PMCID: PMC4322077.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Current understanding of the mechanism of action of the antiepileptic drug lacosamide. Epilepsy Res. 2015 Feb; 110:189-205.
Rogawski MA, Tofighy A, White HS, Matagne A, Wolff C. PMID: 25616473.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimals
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Pediatric super-refractory status epilepticus treated with allopregnanolone. Ann Neurol. 2014 Dec; 76(6):911-5.
Broomall E, Natale JE, Grimason M, Goldstein J, Smith CM, Chang C, Kanes S, Rogawski MA, Wainwright MS. PMID: 25363147; PMCID: PMC4534165.
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PubMed Mentions:
35 Fields:
Translation:
Humans
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Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicol Appl Pharmacol. 2014 Dec 01; 281(2):185-94.
Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. PMID: 25448683; PMCID: PMC4258121.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. PLoS One. 2014; 9(9):e108021.
Chen CY, Matt L, Hell JW, Rogawski MA. PMID: 25229608; PMCID: PMC4168215.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. J Neurosci. 2014 Apr 23; 34(17):5765-75.
Fritsch B, Reis J, Gasior M, Kaminski RM, Rogawski MA. PMID: 24760837; PMCID: PMC3996208.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology (Berl). 2014 Sep; 231(17):3325-32.
Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. PMID: 24705905; PMCID: PMC4134984.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments. Neurotherapeutics. 2014 Apr; 11(2):385-400.
Kaminski RM, Rogawski MA, Klitgaard H. PMID: 24671870; PMCID: PMC3996125.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One. 2013; 8(12):e80922.
Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. PMID: 24349022; PMCID: PMC3862847.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Neuroactive steroids for the treatment of status epilepticus. Epilepsia. 2013 Sep; 54 Suppl 6:93-8.
Rogawski MA, Loya CM, Reddy K, Zolkowska D, Lossin C. PMID: 24001085; PMCID: PMC3772544.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimals
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Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia. 2013 Aug; 54 Suppl 4:13-23.
Galanopoulou AS, Kokaia M, Loeb JA, Nehlig A, Pitkänen A, Rogawski MA, Staley KJ, Whittemore VH, Dudek FE. PMID: 23909850; PMCID: PMC3747731.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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Issues related to development of new antiseizure treatments. Epilepsia. 2013 Aug; 54 Suppl 4:24-34.
Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. PMID: 23909851; PMCID: PMC3947404.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Proconvulsant actions of intrahippocampal botulinum neurotoxin B in the rat. Neuroscience. 2013 Nov 12; 252:253-61.
Bröer S, Zolkowska D, Gernert M, Rogawski MA. PMID: 23906638; PMCID: PMC4530632.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Seizure protection by intrapulmonary delivery of midazolam in mice. Neuropharmacology. 2013 Oct; 73:425-31.
Dhir A, Zolkowska D, Rogawski MA. PMID: 23774136.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Long-lasting attenuation of amygdala-kindled seizures after convection-enhanced delivery of botulinum neurotoxins a and B into the amygdala in rats. J Pharmacol Exp Ther. 2013 Sep; 346(3):528-34.
Gasior M, Tang R, Rogawski MA. PMID: 23772062; PMCID: PMC3876783.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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The intrinsic severity hypothesis of pharmacoresistance to antiepileptic drugs. Epilepsia. 2013 May; 54 Suppl 2:33-40.
Rogawski MA. PMID: 23646969.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Glia and epilepsy: excitability and inflammation. Trends Neurosci. 2013 Mar; 36(3):174-84.
Devinsky O, Vezzani A, Najjar S, De Lanerolle NC, Rogawski MA. PMID: 23298414.
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PubMed Mentions:
346 Fields:
Translation:
HumansAnimalsCells
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Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist. Acta Neurol Scand Suppl. 2013; (197):19-24.
Rogawski MA, Hanada T. PMID: 23480152; PMCID: PMC4506647.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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AMPA receptors as a molecular target in epilepsy therapy. Acta Neurol Scand Suppl. 2013; (197):9-18.
Rogawski MA. PMID: 23480151; PMCID: PMC4506648.
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PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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How theories evolved concerning the mechanism of action of barbiturates. Epilepsia. 2012 Dec; 53 Suppl 8:12-25.
Löscher W, Rogawski MA. PMID: 23205959.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Altered fast and slow inactivation of the N440K Nav1.4 mutant in a periodic paralysis syndrome. Neurology. 2012 Sep 04; 79(10):1033-40.
Lossin C, Nam TS, Shahangian S, Rogawski MA, Choi SY, Kim MK, Sunwoo IN. PMID: 22914841.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72.
Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. PMID: 22889812; PMCID: PMC3529644.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology. 2012 Aug 07; 79(6):589-96.
French JA, Krauss GL, Biton V, Squillacote D, Yang H, Laurenza A, Kumar D, Rogawski MA. PMID: 22843280; PMCID: PMC3413761.
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PubMed Mentions:
153 Fields:
Translation:
HumansCTClinical Trials
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Compromised function in the Na(v)1.2 Dravet syndrome mutation R1312T. Neurobiol Dis. 2012 Sep; 47(3):378-84.
Lossin C, Shi X, Rogawski MA, Hirose S. PMID: 22677033.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Role of neurosteroids in the anticonvulsant activity of midazolam. Br J Pharmacol. 2012 Apr; 165(8):2684-91.
Dhir A, Rogawski MA. PMID: 22014182; PMCID: PMC3423249.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 01; 21(13):2923-35.
Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. PMID: 22466801; PMCID: PMC3373240.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Propofol hemisuccinate suppresses cortical spreading depression. Neurosci Lett. 2012 Apr 11; 514(1):67-70.
Dhir A, Lossin C, Rogawski MA. PMID: 22390898.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther. 2012 May; 341(2):435-46.
Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. PMID: 22328574; PMCID: PMC3336809.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Mechanisms of action of antiseizure drugs. Handb Clin Neurol. 2012; 108:663-81.
Porter RJ, Dhir A, Macdonald RL, Rogawski MA. PMID: 22939059.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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Disclosure of clinical trial results when product development is abandoned. Sci Transl Med. 2011 Sep 28; 3(102):102cm29.
Rogawski MA, Federoff HJ. PMID: 21957167.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Treatment of infantile spasms: emerging insights from clinical and basic science perspectives. J Child Neurol. 2011 Nov; 26(11):1411-21.
Stafstrom CE, Arnason BG, Baram TZ, Catania A, Cortez MA, Glauser TA, Pranzatelli MR, Riikonen R, Rogawski MA, Shinnar S, Swann JW. PMID: 21719797.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis. Neuropharmacology. 2011 Jul-Aug; 61(1-2):133-7.
Kaminski RM, Rogawski MA. PMID: 21458468; PMCID: PMC3105122.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Curr. 2011 Mar; 11(2):56-63.
Rogawski MA. PMID: 21686307; PMCID: PMC3117497.
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PubMed Mentions:
95
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A new policy for disclosure of competing interests. Epilepsy Curr. 2011 Jan; 11(1):7-8.
Rogawski MA. PMID: 21461259; PMCID: PMC3063576.
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To Our Readers and the AES Membership. Epilepsy Curr. 2011 Jan; 11(1):7.
Bergey GK, Rogawski MA, French J, Stafstrom CE. PMID: 21461258; PMCID: PMC3063567.
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"Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia. 2010 Dec; 51 Suppl 5:1-5.
Noebels JL, Avoli M, Rogawski M, Olsen R, Delgado-Escueta AV. PMID: 21208201; PMCID: PMC4651849.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Migraine and epilepsy: Shared mechanisms?. Epilepsia. 2010 Dec 1; 51(s5):80-80.
Rogawski RM. .
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Neurosteroids on the epilepsy chessboard-keeping seizures in check. Epilepsy Curr. 2010 Nov; 10(6):161-3.
Rogawski MA. PMID: 21157546; PMCID: PMC3001027.
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PubMed Mentions:
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Seizure protection by intrapulmonary delivery of propofol hemisuccinate. J Pharmacol Exp Ther. 2011 Jan; 336(1):215-22.
Dhir A, Zolkowska D, Murphy RB, Rogawski MA. PMID: 20837991.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Neurotherapeutics to publish primary research papers. Neurotherapeutics. 2010 Jul 1; 7(3):229-229.
Faden FA, Bakshi BR, Rogawski RM. .
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Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. Epilepsia. 2010 Aug; 51(8):1385-94.
Gasior M, Yankura J, Hartman AL, French A, Rogawski MA. PMID: 20491877.
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PubMed Mentions:
26 Fields:
Translation:
Animals
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Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model. Epilepsy Res. 2010 May; 89(2-3):254-60.
Reddy DS, Rogawski MA. PMID: 20172694; PMCID: PMC2854307.
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PubMed Mentions:
52 Fields:
Translation:
Animals
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Neurosteroids as endogenous regulators of seizure susceptibility and use in the treatment of epilepsy. Epilepsia. 2010; 51(Suppl 5):84.
Reddy DS, Rogawski MA. PMID: 25147407; PMCID: PMC4137784.
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PubMed Mentions:
10 Fields:
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Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit. Epilepsy Behav. 2009 Sep; 16(1):3-46.
Schachter SC, Guttag J, Schiff SJ, Schomer DL, Summit Contributors. PMID: 19780225; PMCID: PMC8118381.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. Epilepsia. 2010 Jan; 51(1):108-17.
Fritsch B, Stott JJ, Joelle Donofrio J, Rogawski MA. PMID: 19682025; PMCID: PMC4535693.
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33 Fields:
Translation:
Animals
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17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities. Eur J Pharmacol. 2009 Sep 01; 617(1-3):68-73.
Runyon SP, Orr M, Navarro HA, Kepler JA, Rogawski MA, Kaminski RM, Cook CE. PMID: 19577558; PMCID: PMC5433526.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis. Neuroscience. 2009 Sep 29; 163(1):415-29.
Fritsch B, Qashu F, Figueiredo TH, Aroniadou-Anderjaska V, Rogawski MA, Braga MF. PMID: 19540312; PMCID: PMC2733834.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Topiramate reduces excitability in the basolateral amygdala by selectively inhibiting GluK1 (GluR5) kainate receptors on interneurons and positively modulating GABAA receptors on principal neurons. J Pharmacol Exp Ther. 2009 Aug; 330(2):558-66.
Braga MF, Aroniadou-Anderjaska V, Li H, Rogawski MA. PMID: 19417176.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Nontraditional epilepsy treatment approaches. Neurotherapeutics. 2009 Apr; 6(2):213-7.
Rogawski MA, Holmes GL. PMID: 19332312; PMCID: PMC5084196.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Convection-enhanced delivery in the treatment of epilepsy. Neurotherapeutics. 2009 Apr; 6(2):344-51.
Rogawski MA. PMID: 19332329; PMCID: PMC2753495.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
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Neurosteroid replacement therapy for catamenial epilepsy. Neurotherapeutics. 2009 Apr; 6(2):392-401.
Reddy DS, Rogawski MA. PMID: 19332335; PMCID: PMC2682439.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimals
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Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia. 2009 Jan; 50 Suppl 1:53-8.
Biagini G, Longo D, Baldelli E, Zoli M, Rogawski MA, Bertazzoni G, Avoli M. PMID: 19125849; PMCID: PMC4873280.
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PubMed Mentions:
27 Fields:
Translation:
Animals
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Common mechanisms in migraine and epilepsy: a comment. Arch Neurol. 2008 Nov; 65(11):1546; author reply 1546-7.
Schürks M. PMID: 19001180.
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1 Fields:
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Humans
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Intrinsic severity as a determinant of antiepileptic drug refractoriness. Epilepsy Curr. 2008 Sep-Oct; 8(5):127-30.
Rogawski MA, Johnson MR. PMID: 18852835; PMCID: PMC2566613.
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PubMed Mentions:
45
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New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels. Curr Neurol Neurosci Rep. 2008 Jul; 8(4):345-52.
Rogawski MA, Bazil CW. PMID: 18590620; PMCID: PMC2587091.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Brivaracetam: a rational drug discovery success story. Br J Pharmacol. 2008 Aug; 154(8):1555-7.
Rogawski MA. PMID: 18552880; PMCID: PMC2518467.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Common pathophysiologic mechanisms in migraine and epilepsy. Arch Neurol. 2008 Jun; 65(6):709-14.
Rogawski MA. PMID: 18541791.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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The anticonvulsant activity of acetone does not depend upon its metabolites. Epilepsia. 2008 May; 49(5):936-7.
Gasior M, Hartman AL, Rogawski MA. PMID: 18454785.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry. 2008 Sep; 13(9):858-72.
Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK. PMID: 18332879; PMCID: PMC2804880.
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PubMed Mentions:
86 Fields:
Translation:
Animals
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Efficacy of the ketogenic diet in the 6-Hz seizure test. Epilepsia. 2008 Feb; 49(2):334-9.
Hartman AL, Lyle M, Rogawski MA, Gasior M. PMID: 18070095; PMCID: PMC2390715.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Calcium currents burst back: a possible role for dendrites in epileptogenesis. Epilepsy Curr. 2007 Sep-Oct; 7(5):140-1.
Dudek FE, Rogawski MA. PMID: 17998977; PMCID: PMC2043133.
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PubMed Mentions:
2
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Prolonged attenuation of amygdala-kindled seizure measures in rats by convection-enhanced delivery of the N-type calcium channel antagonists omega-conotoxin GVIA and omega-conotoxin MVIIA. J Pharmacol Exp Ther. 2007 Nov; 323(2):458-68.
Gasior M, White NA, Rogawski MA. PMID: 17717191; PMCID: PMC2257985.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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The neuropharmacology of the ketogenic diet. Pediatr Neurol. 2007 May; 36(5):281-92.
Hartman AL, Gasior M, Vining EP, Rogawski MA. PMID: 17509459; PMCID: PMC1940242.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimals
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The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid. Epilepsia. 2007 Apr; 48(4):793-800.
Gasior M, French A, Joy MT, Tang RS, Hartman AL, Rogawski MA. PMID: 17386058.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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The ketogenic diet: stoking the powerhouse of the cell. Epilepsy Curr. 2007 Mar-Apr; 7(2):58-60.
Rho JM, Rogawski MA. PMID: 17505556; PMCID: PMC1867088.
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PubMed Mentions:
4
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Molecular targets for antiepileptic drug development. Neurotherapeutics. 2007 Jan; 4(1):18-61.
Meldrum BS, Rogawski MA. PMID: 17199015; PMCID: PMC1852436.
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PubMed Mentions:
128 Fields:
Translation:
HumansAnimals
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Point-counterpoint: Do interictal spikes trigger seizures or protect against them? Epilepsy Curr. 2006 Nov-Dec; 6(6):197-8.
Rogawski MA. PMID: 17260058; PMCID: PMC1783488.
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PubMed Mentions:
10
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Support for the NIH public access policy. Science. 2006 Sep 15; 313(5793):1572.
Rogawski MA, Suber P. PMID: 16973859.
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PubMed Mentions: Fields:
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Neuroprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol. 2006 Sep; 17(5-6):431-9.
Gasior M, Rogawski MA, Hartman AL. PMID: 16940764; PMCID: PMC2367001.
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PubMed Mentions:
177 Fields:
Translation:
HumansAnimalsCells
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Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models. Epilepsy Res. 2006 Aug; 70(2-3):200-10.
Motamedi GK, Salazar P, Smith EL, Lesser RP, Webber WR, Ortinski PI, Vicini S, Rogawski MA. PMID: 16815680.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy. Exp Neurol. 2006 Oct; 201(2):519-24.
Biagini G, Baldelli E, Longo D, Pradelli L, Zini I, Rogawski MA, Avoli M. PMID: 16780839.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res. 2006 Jun; 69(3):273-94.
Rogawski MA. PMID: 16621450; PMCID: PMC1562526.
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PubMed Mentions:
79 Fields:
Translation:
HumansAnimals
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The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors. J Pharmacol Exp Ther. 2006 May; 317(2):694-703.
Kaminski RM, Marini H, Ortinski PI, Vicini S, Rogawski MA. PMID: 16415088.
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PubMed Mentions:
13 Fields:
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HumansAnimalsCells
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Molecular targets versus models for new antiepileptic drug discovery. Epilepsy Res. 2006 Jan; 68(1):22-8.
Rogawski MA. PMID: 16377151; PMCID: PMC1373807.
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PubMed Mentions:
25 Fields:
Translation:
Animals
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CHAPTER 13 Alcohol Withdrawal Seizures. . 2006 Jan 1; (Br J Psychiatry1331978):161-177.
N'GOUEMO NP, ROGAWSKI RM. .
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Update on the neurobiology of alcohol withdrawal seizures. Epilepsy Curr. 2005 Nov-Dec; 5(6):225-30.
Rogawski MA. PMID: 16372057; PMCID: PMC1312739.
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PubMed Mentions:
27
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Astrocytes get in the act in epilepsy. Nat Med. 2005 Sep; 11(9):919-20.
Rogawski MA. PMID: 16145568; PMCID: PMC1373800.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala. J Neurochem. 2005 Sep; 94(6):1728-38.
Gryder DS, Castaneda DC, Rogawski MA. PMID: 16045445; PMCID: PMC1352164.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Anticonvulsant activity of androsterone and etiocholanolone. Epilepsia. 2005 Jun; 46(6):819-27.
Kaminski RM, Marini H, Kim WJ, Rogawski MA. PMID: 15946323; PMCID: PMC1181535.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Regulation of brain water: is there a role for aquaporins in epilepsy? Epilepsy Curr. 2005 May-Jun; 5(3):104-6.
Dudek FE, Rogawski MA. PMID: 16145616; PMCID: PMC1198631.
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PubMed Mentions:
6
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Adult murine skeletal muscle contains cells that can differentiate into beating cardiomyocytes in vitro. PLoS Biol. 2005 Apr; 3(4):e87.
Winitsky SO, Gopal TV, Hassanzadeh S, Takahashi H, Gryder D, Rogawski MA, Takeda K, Yu ZX, Xu YH, Epstein ND. PMID: 15757365; PMCID: PMC1064849.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 2005 Jan; 48(1):14-24.
Reddy DS, O'Malley BW, Rogawski MA. PMID: 15617723.
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PubMed Mentions:
61 Fields:
Translation:
Animals
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Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. Am J Pathol. 2004 Sep; 165(3):1007-18.
Ivanov SV, Ward JM, Tessarollo L, McAreavey D, Sachdev V, Fananapazir L, Banks MK, Morris N, Djurickovic D, Devor-Henneman DE, Wei MH, Alvord GW, Gao B, Richardson JA, Minna JD, Rogawski MA, Lerman MI. PMID: 15331424; PMCID: PMC1618598.
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PubMed Mentions:
51 Fields:
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AnimalsCells
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The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nat Med. 2004 Jul; 10(7):685-92.
Rogawski MA, Löscher W. PMID: 15229516.
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PubMed Mentions:
121 Fields:
Translation:
Humans
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What is the rationale for new treatment strategies in Alzheimer's disease? CNS Spectr. 2004 Jul; 9(7 Suppl 5):6-12.
Rogawski MA. PMID: 15241294.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. Epilepsia. 2004 Jul; 45(7):864-7.
Kaminski RM, Livingood MR, Rogawski MA. PMID: 15230714.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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The neurobiology of antiepileptic drugs. Nat Rev Neurosci. 2004 Jul; 5(7):553-64.
Rogawski MA, Löscher W. PMID: 15208697.
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PubMed Mentions:
306 Fields:
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HumansAnimalsCells
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Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 2004 Jun; 46(8):1097-104.
Kaminski RM, Banerjee M, Rogawski MA. PMID: 15111016.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. J Pharmacol Exp Ther. 2004 Jul; 310(1):230-9.
Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. PMID: 14982969.
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PubMed Mentions:
77 Fields:
Translation:
Animals
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Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons. J Neurosci. 2003 Aug 06; 23(18):7069-74.
Gryder DS, Rogawski MA. PMID: 12904467; PMCID: PMC6740668.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice. Epilepsy Res. 2003 Jun-Jul; 55(1-2):71-82.
Salazar P, Tapia R, Rogawski MA. PMID: 12948618.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Clinical spectrum of succinic semialdehyde dehydrogenase deficiency. Neurology. 2003 May 13; 60(9):1413-7.
Pearl PL, Gibson KM, Acosta MT, Vezina LG, Theodore WH, Rogawski MA, Novotny EJ, Gropman A, Conry JA, Berry GT, Tuchman M. PMID: 12743223.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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GluR5 kainate receptors, seizures, and the amygdala. Ann N Y Acad Sci. 2003 Apr; 985:150-62.
Rogawski MA, Gryder D, Castaneda D, Yonekawa W, Banks MK, Lia H. PMID: 12724156.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy. Ann Neurol. 2003 Mar; 53(3):288-91.
Rogawski MA. PMID: 12601696.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease. CNS Drug Rev. 2003; 9(3):275-308.
Rogawski MA, Wenk GL. PMID: 14530799; PMCID: PMC6741669.
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PubMed Mentions:
124 Fields:
Translation:
HumansAnimals
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Does P-glycoprotein play a role in pharmacoresistance to antiepileptic drugs? Epilepsy Behav. 2002 Dec; 3(6):493-495.
Rogawski MA. PMID: 12609240.
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2 Fields:
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Antiepileptogenesis by Deep Brain Stimulation. Epilepsy Curr. 2002 Sep; 2(5):153-154.
Rogawski MA. PMID: 15309125; PMCID: PMC321047.
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PubMed Mentions:
1
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The Epileptic Neuron Redux. Epilepsy Curr. 2002 Sep; 2(5):151-152.
Dudek FE, Rogawski MA. PMID: 15309124; PMCID: PMC321046.
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PubMed Mentions:
4
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Epileptiform activity extinguished by amygdala infusion of the neurotoxin ibotenate in a rat model of temporal lobe epilepsy. J Neurosurg. 2002 Aug; 97(2):450-4.
Pace JR, Lonser RR, Kirkby RD, Jeffries N, Rogawski MA, Oldfield EH. PMID: 12186475.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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New strategies for the identification of drugs to prevent the development or progression of epilepsy. Epilepsy Res. 2002 Jun; 50(1-2):71-8.
Schmidt D, Rogawski MA. PMID: 12151119.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. J Neurosci. 2002 May 01; 22(9):3795-805.
Reddy DS, Rogawski MA. PMID: 11978855; PMCID: PMC6758375.
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PubMed Mentions:
103 Fields:
Translation:
Animals
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New Evidence Supporting a Role for T-Type Ca(2+) Channels in Absence Epilepsy and in the Action of Ethosuximide. Epilepsy Curr. 2002 Mar; 2(2):57.
Rogawski MA. PMID: 15309167; PMCID: PMC320969.
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PubMed Mentions:
2
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Neurosteroids and infantile spasms: the deoxycorticosterone hypothesis. Int Rev Neurobiol. 2002; 49:199-219.
Rogawski MA, Reddy DS. PMID: 12040893.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors. Neurobiol Dis. 2001 Dec; 8(6):1069-81.
Basile AS, Koustova E, Ioan P, Rizzoli S, Rogawski MA, Usherwood PN. PMID: 11741402.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Future directions for epilepsy research. Neurology. 2001 Nov 13; 57(9):1536-42.
Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. PMID: 11706087.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Kainate receptor-mediated heterosynaptic facilitation in the amygdala. Nat Neurosci. 2001 Jun; 4(6):612-20.
Li H, Chen A, Xing G, Wei ML, Rogawski MA. PMID: 11369942.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Generalized epileptic disorders: an update. Epilepsia. 2001 Apr; 42(4):445-57.
Avoli M, Rogawski MA, Avanzini G. PMID: 11440339.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Input-specific LTP and depotentiation in the basolateral amygdala. Neuroreport. 2001 Mar 05; 12(3):635-40.
Aroniadou-Anderjaska V, Post RM, Rogawski MA, Li H. PMID: 11234779.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. Epilepsia. 2001 Mar; 42(3):328-36.
Reddy DS, Kim HY, Rogawski MA. PMID: 11442149.
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PubMed Mentions:
71 Fields:
Translation:
HumansAnimals
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Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia. 2001 Mar; 42(3):337-44.
Reddy DS, Rogawski MA. PMID: 11442150.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. J Clin Invest. 2001 Mar; 107(6):737-44.
Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS. PMID: 11254673; PMCID: PMC208947.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse. Neuropharmacology. 2001; 40(1):28-35.
Rogawski MA, Kurzman PS, Yamaguchi SI, Li H. PMID: 11077068.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. J Pharmacol Exp Ther. 2000 Dec; 295(3):1241-8.
Reddy DS, Rogawski MA. PMID: 11082461.
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PubMed Mentions:
64 Fields:
Translation:
Animals
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Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy. J Pharmacol Exp Ther. 2000 Sep; 294(3):909-15.
Reddy DS, Rogawski MA. PMID: 10945840.
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PubMed Mentions:
44 Fields:
Translation:
Animals
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KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy. Trends Neurosci. 2000 Sep; 23(9):393-8.
Rogawski MA. PMID: 10941184.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Re: Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor". Epilepsia. 2000 Jul; 41(7):918-9.
Rogawski MA, Wasterlain CG, Mazarati AM. PMID: 10897169.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4926-31.
Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. PMID: 10781100; PMCID: PMC18334.
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PubMed Mentions:
384 Fields:
Translation:
AnimalsCells
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Felbamate block of recombinant N-methyl-D-aspartate receptors: selectivity for the NR2B subunit. Epilepsy Res. 2000 Mar; 39(1):47-55.
Harty TP, Rogawski MA. PMID: 10690753.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability. Amino Acids. 2000; 19(1):133-49.
Rogawski MA. PMID: 11026482.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Convulsant actions of the neurosteroid pregnenolone sulfate in mice. Brain Res. 1999 Jun 12; 831(1-2):119-24.
Kokate TG, Juhng KN, Kirkby RD, Llamas J, Yamaguchi S, Rogawski MA. PMID: 10411990.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha). Epilepsy Res. 1999 Apr; 34(2-3):177-86.
Juhng KN, Kokate TG, Yamaguchi S, Kim BY, Rogowski RS, Blaustein MP, Rogawski MA. PMID: 10210033.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. J Pharmacol Exp Ther. 1999 Feb; 288(2):679-84.
Kokate TG, Banks MK, Magee T, Yamaguchi S, Rogawski MA. PMID: 9918575.
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PubMed Mentions:
44 Fields:
Translation:
Animals
-
AMPA receptors in epilepsy and as targets for antiepileptic drugs. Adv Neurol. 1999; 79:947-63.
Rogawski MA, Donevan SD. PMID: 10514878.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines. Neuroscience. 1998 Dec; 87(3):615-29.
Donevan SD, Rogawski MA. PMID: 9758228.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Lack of anticonvulsant tolerance to the neuroactive steroid pregnanolone in mice. J Pharmacol Exp Ther. 1998 Nov; 287(2):553-8.
Kokate TG, Yamaguchi S, Pannell LK, Rajamani U, Carroll DM, Grossman AB, Rogawski MA. PMID: 9808680.
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PubMed Mentions:
36 Fields:
Translation:
Animals
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GluR5 kainate receptor mediated synaptic transmission in rat basolateral amygdala in vitro. Neuropharmacology. 1998 Oct-Nov; 37(10-11):1279-86.
Li H, Rogawski MA. PMID: 9849665.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL. J Pharmacol Exp Ther. 1998 May; 285(2):767-76.
Grauert M, Rho JM, Subramaniam S, Rogawski MA. PMID: 9580625.
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PubMed Mentions: Fields:
Translation:
Animals
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Bidirectional synaptic plasticity in the rat basolateral amygdala: characterization of an activity-dependent switch sensitive to the presynaptic metabotropic glutamate receptor antagonist 2S-alpha-ethylglutamic acid. J Neurosci. 1998 Mar 01; 18(5):1662-70.
Li H, Weiss SR, Chuang DM, Post RM, Rogawski MA. PMID: 9464991; PMCID: PMC6792614.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Mechanism-specific pathways for new antiepileptic drug discovery. Adv Neurol. 1998; 76:11-27.
Rogawski MA. PMID: 9408460.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Barbiturate-like actions of the propanediol dicarbamates felbamate and meprobamate. J Pharmacol Exp Ther. 1997 Mar; 280(3):1383-91.
Rho JM, Donevan SD, Rogawski MA. PMID: 9067327.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons. J Physiol. 1996 Dec 01; 497 ( Pt 2):509-22.
Rho JM, Donevan SD, Rogawski MA. PMID: 8961191; PMCID: PMC1161000.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels. Mol Pharmacol. 1996 Nov; 50(5):1167-77.
Rogowski RS, Collins JH, O'Neill TJ, Gustafson TA, Werkman TR, Rogawski MA, Tenenholz TC, Weber DJ, Blaustein MP. PMID: 8913348.
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PubMed Mentions:
12 Fields:
Translation:
Cells
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Ibogaine block of the NMDA receptor: in vitro and in vivo studies. Neuropharmacology. 1996 Apr; 35(4):423-31.
Chen K, Kokate TG, Donevan SD, Carroll FI, Rogawski MA. PMID: 8793904.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Multiple actions of arylalkylamine arthropod toxins on the N-methyl-D-aspartate receptor. Neuroscience. 1996 Jan; 70(2):361-75.
Donevan SD, Rogawski MA. PMID: 8848146.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists. Neuropharmacology. 1996; 35(12):1709-19.
Grant KA, Colombo G, Grant J, Rogawski MA. PMID: 9076750.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology. 1996; 35(8):1049-56.
Kokate TG, Cohen AL, Karp E, Rogawski MA. PMID: 9121607.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells. J Pharmacol Exp Ther. 1996 Jan; 276(1):143-9.
Hough CJ, Irwin RP, Gao XM, Rogawski MA, Chuang DM. PMID: 8558424.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Docosahexaenoic acid block of neuronal voltage-gated K+ channels: subunit selective antagonism by zinc. Neuropharmacology. 1996; 35(7):969-82.
Poling JS, Vicini S, Rogawski MA, Salem N. PMID: 8938727.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. Neuropharmacology. 1996; 35(7):983-91.
Poling JS, Rogawski MA, Salem N, Vicini S. PMID: 8938728.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite. J Pharmacol Exp Ther. 1996 Jan; 276(1):161-8.
Subramaniam S, Donevan SD, Rogawski MA. PMID: 8558426.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Potassium channels. Neuropharmacology. 1996; 35(7):759.
Levitan IB, Rogawski MA. PMID: 8938708.
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PubMed Mentions:
1 Fields:
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Effects of D1 and D2 dopamine receptor antagonists and catecholamine depleting agents on the locomotor stimulation induced by dizocilpine in mice. Behav Brain Res. 1995 Oct; 70(2):145-51.
Lapin IP, Rogawski MA. PMID: 8561905.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9298-302.
Donevan SD, Rogawski MA. PMID: 7568121; PMCID: PMC40972.
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PubMed Mentions:
109 Fields:
Translation:
AnimalsCells
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Anticonvulsant efficacy of ADCI (5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine) after acute and chronic dosing in mice. Epilepsia. 1995 Jun; 36(6):566-71.
Rogawski MA, Le DQ, Uyakul D, Pannell LK, Subramaniam S, Yamaguchi S, Kokate TG. PMID: 7555968.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Felbamate block of the N-methyl-D-aspartate receptor. J Pharmacol Exp Ther. 1995 May; 273(2):878-86.
Subramaniam S, Rho JM, Penix L, Donevan SD, Fielding RP, Rogawski MA. PMID: 7752093.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice. Neuropharmacology. 1994 Dec; 33(12):1515-22.
Mattia D, Nagao T, Rogawski MA, Avoli M. PMID: 7760973.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies. J Pharmacol Exp Ther. 1994 Nov; 271(2):677-82.
Irwin RP, Lin SZ, Rogawski MA, Purdy RH, Paul SM. PMID: 7965782.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity. J Pharmacol Exp Ther. 1994 Oct; 271(1):25-9.
Donevan SD, Yamaguchi S, Rogawski MA. PMID: 7525924.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Reply. Annals of Neurology. 1994 Oct 1; 36(4):677-678.
Rho RJ, Donevan DS, Subramaniam SS, Rogawski RM. .
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Publisher Site Mentions:
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Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. J Pharmacol Exp Ther. 1994 Sep; 270(3):1223-9.
Kokate TG, Svensson BE, Rogawski MA. PMID: 7932175.
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PubMed Mentions:
109 Fields:
Translation:
AnimalsCells
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Riluzole in amyotrophic lateral sclerosis. N Engl J Med. 1994 Jul 28; 331(4):272-3; author reply 273-4.
McRae KD. PMID: 8015578.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology. 1994 Jun; 33(6):795-804.
Svensson BE, Werkman TR, Rogawski MA. PMID: 7936117.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Ann Neurol. 1994 Feb; 35(2):229-34.
Rho JM, Donevan SD, Rogawski MA. PMID: 8109904.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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RTI-4793-14, a new ligand with high affinity and selectivity for the (+)-MK801-insensitive [3H]1-]1-(2-thienyl)cyclohexyl]piperidine binding site (PCP site 2) of guinea pig brain. Synapse. 1994 Jan; 16(1):59-65.
Goodman CB, Thomas DN, Pert A, Emilien B, Cadet JL, Carroll FI, Blough BE, Mascarella SW, Rogawski MA, Subramaniam S, et al. PMID: 8134901.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Hydrophobic interactions of n-alkyl diamines with the N-methyl-D-aspartate receptor: voltage-dependent and -independent blocking sites. Mol Pharmacol. 1994 Jan; 45(1):117-24.
Subramaniam S, Donevan SD, Rogawski MA. PMID: 8302270.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines. Trends Pharmacol Sci. 1993 Sep; 14(9):325-31.
Rogawski MA. PMID: 7504360.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimals
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Tityustoxin-K alpha, a structurally novel and highly potent K+ channel peptide toxin, interacts with the alpha-dendrotoxin binding site on the cloned Kv1.2 K+ channel. Mol Pharmacol. 1993 Aug; 44(2):430-6.
Werkman TR, Gustafson TA, Rogowski RS, Blaustein MP, Rogawski MA. PMID: 8355670.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. J Neurosci. 1993 Aug; 13(8):3211-21.
ffrench-Mullen JM, Barker JL, Rogawski MA. PMID: 8101867; PMCID: PMC6576525.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models. Epilepsy Res. 1993 Jul; 15(3):179-84.
Yamaguchi S, Donevan SD, Rogawski MA. PMID: 7693450.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron. 1993 Jan; 10(1):51-9.
Donevan SD, Rogawski MA. PMID: 7678966.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism. Neurosci Lett. 1992 Dec 07; 147(2):213-6.
Subramaniam S, Donevan SD, Rogawski MA. PMID: 1283458.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Phencyclidine block of calcium current in isolated guinea-pig hippocampal neurones. J Physiol. 1992 Oct; 456:85-105.
Ffrench-Mullen JM, Rogawski MA. PMID: 1338108; PMCID: PMC1175673.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Charybdotoxin, dendrotoxin and mast cell degranulating peptide block the voltage-activated K+ current of fibroblast cells stably transfected with NGK1 (Kv1.2) K+ channel complementary DNA. Neuroscience. 1992 Oct; 50(4):935-46.
Werkman TR, Kawamura T, Yokoyama S, Higashida H, Rogawski MA. PMID: 1280351.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report. Drugs. 1992 Sep; 44(3):279-92.
Rogawski MA. PMID: 1382930.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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High concentrations of neutral amino acids activate NMDA receptor currents in rat hippocampal neurons. Neurosci Lett. 1992 Jul 06; 141(1):97-100.
Pace JR, Martin BM, Paul SM, Rogawski MA. PMID: 1324446.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons. Neurosci Lett. 1992 Jul 06; 141(1):30-4.
Irwin RP, Maragakis NJ, Rogawski MA, Purdy RH, Farb DH, Paul SM. PMID: 1387199.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons. Mol Pharmacol. 1992 Apr; 41(4):727-35.
Donevan SD, Jones SM, Rogawski MA. PMID: 1373801.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Protection against dendrotoxin-induced clonic seizures in mice by anticonvulsant drugs. Brain Res. 1992 Mar 13; 575(1):138-42.
Coleman MH, Yamaguchi S, Rogawski MA. PMID: 1504773.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice. Epilepsy Res. 1992 Mar; 11(1):9-16.
Yamaguchi S, Rogawski MA. PMID: 1563341.
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PubMed Mentions:
34 Fields:
Translation:
Animals
-
Comparison of the effects of the uncompetitive N-methyl-D-aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine (ADCI) with its structural analogs dizocilpine (MK-801) and carbamazepine on ethanol withdrawal seizures. J Pharmacol Exp Ther. 1992 Mar; 260(3):1017-22.
Grant KA, Snell LD, Rogawski MA, Thurkauf A, Tabakoff B. PMID: 1545374.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Anticonvulsant 1-phenylcycloalkylamines: two analogues with low motor toxicity when orally administered. Epilepsia. 1992 Jan-Feb; 33(1):188-94.
Blake PA, Yamaguchi S, Thurkauf A, Rogawski MA. PMID: 1531130.
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PubMed Mentions: Fields:
Translation:
Animals
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Muscarinic antagonists attenuate dizocilpine-induced hypermotility in mice. Life Sci. 1992; 50(9):PL59-64.
Lapin IP, Rogawski MA. PMID: 1740967.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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New antiepileptic drugs: from serendipity to rational discovery. Epilepsia. 1992; 33 Suppl 1:S1-6.
Porter RJ, Rogawski MA. PMID: 1379532.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Theoretical and practical considerations concerning the use of NMDA antagonists in the treatment of the epilepsies. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:697A-698A.
Porter RJ, Rogawski MA. PMID: 1386786.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine. J Pharmacol Exp Ther. 1991 Oct; 259(1):30-7.
Rogawski MA, Yamaguchi S, Jones SM, Rice KC, Thurkauf A, Monn JA. PMID: 1920122.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
A model of the T-type calcium current and the low-threshold spike in thalamic neurons. J Neurophysiol. 1991 Sep; 66(3):839-50.
Wang XJ, Rinzel J, Rogawski MA. PMID: 1661326.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Glyburide-sensitive K+ channels in cultured rat hippocampal neurons: activation by cromakalim and energy-depleting conditions. Mol Pharmacol. 1991 Aug; 40(2):308-15.
Politi DM, Rogawski MA. PMID: 1715018.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Tetrahydroaminoacridine block of N-methyl-D-aspartate-activated cation channels in cultured hippocampal neurons. Mol Pharmacol. 1991 May; 39(5):592-8.
Hershkowitz N, Rogawski MA. PMID: 1709720.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol Rev. 1990 Sep; 42(3):223-86.
Rogawski MA, Porter RJ. PMID: 2217531.
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PubMed Mentions:
82 Fields:
Translation:
HumansAnimals
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Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. J Med Chem. 1990 May; 33(5):1452-8.
Thurkauf A, de Costa B, Yamaguchi S, Mattson MV, Jacobson AE, Rice KC, Rogawski MA. PMID: 2329567.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Novel research strategies for antiepileptic therapy. Prog Clin Biol Res. 1990; 361:91-111.
Rogawski MA, Hershkowitz N, Politi DM, Suzuki S, Thurkauf A, Yamaguchi S. PMID: 2290852.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Interaction of phencyclidine with voltage-dependent potassium channels in cultured rat hippocampal neurons: comparison with block of the NMDA receptor-ionophore complex. J Neurosci. 1989 Nov; 9(11):4051-61.
ffrench-Mullen JM, Rogawski MA. PMID: 2555461; PMCID: PMC6569947.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. Br J Pharmacol. 1989 Nov; 98(3):1005-13.
Hershkowitz N, Rogawski MA. PMID: 2556198; PMCID: PMC1854780.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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T-type calcium channels mediate the transition between tonic and phasic firing in thalamic neurons. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7228-32.
Suzuki S, Rogawski MA. PMID: 2550936; PMCID: PMC298030.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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BRL 34915 (cromakalim) enhances voltage-dependent K+ current in cultured rat hippocampal neurons. Eur J Pharmacol. 1989 Sep 01; 168(1):7-14.
Politi DM, Suzuki S, Rogawski MA. PMID: 2583232.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline. J Pharmacol Exp Ther. 1989 Jun; 249(3):708-12.
Rogawski MA, Thurkauf A, Yamaguchi S, Rice KC, Jacobson AE, Mattson MV. PMID: 2659775.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Aminopyridines enhance opening of calcium-activated potassium channels in GH3 anterior pituitary cells. Mol Pharmacol. 1989 Apr; 35(4):458-68.
Rogawski MA. PMID: 2704369.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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A function for REM sleep: regulation of noradrenergic receptor sensitivity. Brain Res. 1988 Nov; 472(3):213-33.
Siegel JM, Rogawski MA. PMID: 3066435; PMCID: PMC9050241.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
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Vasopressin enhances a calcium current in human ACTH-secreting pituitary adenoma cells. FASEB J. 1988 Oct; 2(13):2907-12.
Mollard P, Vacher P, Rogawski MA, Dufy B. PMID: 2844618.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Transient outward current (IA) in clonal anterior pituitary cells: blockade by aminopyridine analogs. Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug; 338(2):125-32.
Rogawski MA. PMID: 3185742.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Phencyclidine selectively blocks the sustained voltage-dependent potassium conductance in PC12 cells. Brain Res. 1988 Jul 19; 456(1):38-48.
Rogawski MA, Pieniek M, Suzuki S, ffrench-Mullen JM. PMID: 2457411.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Phencyclidine at low concentrations selectively blocks the sustained but not the transient voltage-dependent potassium current in cultured hippocampal neurons. Neurosci Lett. 1988 Jun 07; 88(3):325-30.
ffrench-Mullen JM, Rogawski MA, Barker JL. PMID: 3386879.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A slow calcium-dependent chloride conductance in clonal anterior pituitary cells. J Neurophysiol. 1988 Jun; 59(6):1854-70.
Rogawski MA, Inoue K, Suzuki S, Barker JL. PMID: 3404208.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Colchicine neuropathy or vitamin B12 deficiency neuropathy? N Engl J Med. 1987 Nov 12; 317(20):1290-1.
Palopoli JJ, Waxman J. PMID: 2823139.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons. Eur J Pharmacol. 1987 Oct 06; 142(1):169-72.
Rogawski MA. PMID: 2446884.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Electrical properties of cultured human adrenocorticotropin-secreting adenoma cells: effects of high K+, corticotropin-releasing factor, and angiotensin II. Endocrinology. 1987 Jul; 121(1):395-405.
Mollard P, Vacher P, Guerin J, Rogawski MA, Dufy B. PMID: 3036472.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Colchicine myopathy and neuropathy. N Engl J Med. 1987 Jun 18; 316(25):1562-8.
Kuncl RW, Duncan G, Watson D, Alderson K, Rogawski MA, Peper M. PMID: 3035372.
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PubMed Mentions:
80 Fields:
Translation:
Humans
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New directions in neurotransmitter action: dopamine provides some important clues. Trends in Neurosciences. 1987 May 1; 10(5):200-205.
Rogawski RM. .
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Publisher Site Mentions:
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Single voltage-dependent potassium channels in cultured rat hippocampal neurons. J Neurophysiol. 1986 Aug; 56(2):481-93.
Rogawski MA. PMID: 2428951.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Cholecystokinin and cultured spinal neurons. Immunohistochemistry, receptor binding, and neurophysiology. Ann N Y Acad Sci. 1985; 448:403-12.
Rogawski MA, Beinfeld MC, Hays SE, Hökfelt T, Skirboll LR. PMID: 2992347.
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5 Fields:
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AnimalsCells
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The A-current: how ubiquitous a feature of excitable cells is it?. Trends in Neurosciences. 1985 Jan 1; 8:214-219.
Rogawski RM. .
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A transient potassium conductance regulates the excitability of cultured hippocampal and spinal neurons. J Neurosci. 1984 Feb; 4(2):604-9.
Segal M, Rogawski MA, Barker JL. PMID: 6699688; PMCID: PMC6564901.
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PubMed Mentions:
49 Fields:
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AnimalsCells
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Transdermal scopolamine and sialorrhea. Arch Neurol. 1984 Jan; 41(1):15.
Rogawski MA. PMID: 6689882.
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1 Fields:
Translation:
Humans
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Electrophysiological studies of peptide actions on the excitability of cultured nerve and pituitary cells. Clin Exp Hypertens A. 1984; 6(10-11):1701-16.
Barker JL, Dufy B, Owen DG, Rogawski MA. PMID: 6152408.
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AnimalsCells
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Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons. Brain Res. 1983 Nov 28; 280(1):180-5.
Rogawski MA, Barker JL. PMID: 6652477.
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21 Fields:
Translation:
AnimalsCells
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Activation of lateral geniculate neurons by locus coeruleus or dorsal noradrenergic bundle stimulation: selective blockade by the alpha 1-adrenoceptor antagonist prazosin. Brain Res. 1982 Oct 28; 250(1):31-9.
Rogawski MA, Aghajanian GK. PMID: 7139319.
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18 Fields:
Translation:
AnimalsCells
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Cholecystokinin octapeptide: effects on the excitability of cultured spinal neurons. Peptides. 1982 May-Jun; 3(3):545-51.
Rogawski MA. PMID: 6126867.
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AnimalsCells
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Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. J Neurosci. 1981 Oct; 1(10):1148-54.
Rogawski MA, Aghajanian GK. PMID: 6793698; PMCID: PMC6564212.
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PubMed Mentions:
3 Fields:
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AnimalsCells
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Modulation of lateral geniculate neurone excitability by noradrenaline microiontophoresis or locus coeruleus stimulation. Nature. 1980 Oct 23; 287(5784):731-4.
Rogawski MA, Aghajanian GK. PMID: 6253811.
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36 Fields:
Translation:
Animals
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Norepinephrine and serotonin: opposite effects on the activity of lateral geniculate neurons evoked by optic pathway stimulation. Exp Neurol. 1980 Sep; 69(3):678-94.
Rogawski MA, Aghajanian GK. PMID: 7409069.
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PubMed Mentions:
30 Fields:
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AnimalsCells
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Activation of lateral geniculate neurons by norepinephrine: mediation by an alpha-adrenergic receptor. Brain Res. 1980 Jan 27; 182(2):345-59.
Rogawski MA, Aghajanian GK. PMID: 6101983.
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19 Fields:
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AnimalsCells
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Response of central monoaminergic neurons to lisuride: comparison with LSD. Life Sci. 1979 Apr 02; 24(14):1289-97.
Rogawski MA, Aghajanian GK. PMID: 470543.
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13 Fields:
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AnimalsCells
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Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase. J Neurochem. 1979 Apr; 32(4):1219-26.
Rogawski MA, Roth RH, Aghajanian GK. PMID: 285213.
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16 Fields:
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Animals
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Hirschsprung's disease: absence of serotonergic neurons in the aganglionic colon. J Pediatr Surg. 1978 Dec; 13(6D):608-15.
Rogawski MA, Goodrich JT, Gershon MD, Touloukian RJ. PMID: 731360.
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8 Fields:
Translation:
HumansCells
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Oculocutaneous albinism and mental disorder. A report of two autistic boys. Hum Hered. 1978; 28(2):81-5.
Rogawski MA, Funderburk SJ, Cederbaum SD. PMID: 413782.
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6 Fields:
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Humans
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Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum. Mol Pharmacol. 1976 Mar; 12(2):251-62.
Iversen LL, Rogawski MA, Miller RJ. PMID: 4724.
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27 Fields:
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AnimalsCells
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Proceedings:Pre- and postsynaptic actions of neuroleptic drugs. Br J Pharmacol. 1975 Oct; 55(2):297P-298P.
Iversen LL, Miller RJ, Rogawski M. PMID: 1201424; PMCID: PMC1666861.
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1 Fields:
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AnimalsCells
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Effects of ethanol on tryptophan hydroxylase activity from striate synaptosomes. Biochem Pharmacol. 1974 Jul 15; 23(14):1955-62.
Rogawski MA, Knapp S, MAndell AJ. PMID: 4418689.
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AnimalsCells
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Effect of selective destruction of central and peripheral catecholamine-containing neurones with 6-hydroxydopamine on catecholamine excretion in the rat. Br J Pharmacol. 1974 Feb; 50(2):265-70.
Hoeldtke R, Rogawski M, Wurtman RJ. PMID: 4425765; PMCID: PMC1776636.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells