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Michael A Rogawski

Title(s)Professor, Neurology
SchoolUniversity of California, Davis
Phone(916)801-5714
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    TRAINING IN NEUROTHERAPUETICS AND DEVELOPMENT FOR ACADEMIC SCIENTISTS
    NIH/NINDS R25NS099170May 15, 2017 - Feb 28, 2022
    Role: Principal Investigator
    Training in Neurotherapeutics Discovery and Development for Academic Scientists
    NIH/NINDS R25NS077582Mar 1, 2012 - Feb 28, 2017
    Role: Principal Investigator
    Identification of novel therapeutic approaches for TETS and OP intoxication
    NIH/NINDS R21NS072094Sep 30, 2010 - Aug 31, 2013
    Role: Co-Principal Investigator
    Ion Channels in Epilepsy and as Targets for Antiepileptic Drugs
    NIH/NINDS Z01NS002732
    Role: Co-Principal Investigator
    Evaluation Of Novel Epilepsy Treatment Approaches
    NIH/NINDS Z01NS002877
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rogawski MA, Heller AH. Diazepam buccal film for the treatment of acute seizures. Epilepsy Behav. 2019 Nov 05; 106537. PMID: 31699662.
      View in: PubMed
    2. Rogawski MA. Reduced efficacy and risk of seizure aggravation when cannabidiol is used without clobazam. Epilepsy Behav. 2019 Sep 13; 106506. PMID: 31526646.
      View in: PubMed
    3. Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiol Dis. 2019 Mar 21; 104431. PMID: 30905768.
      View in: PubMed
    4. Napoli E, Schneider A, Wang JY, Trivedi A, Carrillo NR, Tassone F, Rogawski M, Hagerman RJ, Giulivi C. Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study. Mol Neurobiol. 2019 May; 56(5):3702-3713. PMID: 30187385.
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    5. Dhir A, Rogawski MA. Determination of minimal steady-state plasma level of diazepam causing seizure threshold elevation in rats. Epilepsia. 2018 05; 59(5):935-944. PMID: 29682729.
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    6. Zolkowska D, Wu CY, Rogawski MA. Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment-resistant status epilepticus. Epilepsia. 2018 10; 59 Suppl 2:220-227. PMID: 29453777.
      View in: PubMed
    7. Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W. Commonalities in epileptogenic processes from different acute brain insults: Do they translate? Epilepsia. 2018 01; 59(1):37-66. PMID: 29247482.
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    8. Wang JY, Trivedi AM, Carrillo NR, Yang J, Schneider A, Giulivi C, Adams P, Tassone F, Kim K, Rivera SM, Lubarr N, Wu CY, Irwin RW, Brinton RD, Olichney JM, Rogawski MA, Hagerman RJ. Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome. Neurotherapeutics. 2017 Oct; 14(4):1073-1083. PMID: 28707277.
      View in: PubMed
    9. Chen CY, Di Lucente J, Lin YC, Lien CC, Rogawski MA, Maezawa I, Jin LW. Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. Neurobiol Dis. 2018 Jan; 109(Pt A):25-32. PMID: 28927958.
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    10. Dingledine R, Coulter DA, Fritsch B, Gorter JA, Lelutiu N, McNamara J, Nadler JV, Pitkänen A, Rogawski MA, Skene P, Sloviter RS, Wang Y, Wadman WJ, Wasterlain C, Roopra A. Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Sci Data. 2017 05 09; 4:170061. PMID: 28485718.
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    11. Vaitkevicius H, Husain AM, Rosenthal ES, Rosand J, Bobb W, Reddy K, Rogawski MA, Cole AJ. First-in-man allopregnanolone use in super-refractory status epilepticus. Ann Clin Transl Neurol. 2017 06; 4(6):411-414. PMID: 28589168.
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    12. Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. Mol Pharmacol. 2017 07; 92(1):88-99. PMID: 28428226.
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    13. Lévesque M, Herrington R, Leclerc L, Rogawski MA, Avoli M. Allopregnanolone decreases interictal spiking and fast ripples in an animal model of mesial temporal lobe epilepsy. Neuropharmacology. 2017 Jul 15; 121:12-19. PMID: 28416442.
      View in: PubMed
    14. Ciarlone SL, Wang X, Rogawski MA, Weeber EJ. Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model. Neuropharmacology. 2017 04; 116:142-150. PMID: 27986596.
      View in: PubMed
    15. Rogawski MA. A New SV2A Ligand for Epilepsy. Cell. 2016 Oct 20; 167(3):587. PMID: 27768878.
      View in: PubMed
    16. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. PMID: 27467073.
      View in: PubMed
    17. Rogawski MA, Löscher W, Rho JM. Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet. Cold Spring Harb Perspect Med. 2016 05 02; 6(5). PMID: 26801895.
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    18. Rogawski MA. A fatty acid in the MCT ketogenic diet for epilepsy treatment blocks AMPA receptors. Brain. 2016 Feb; 139(Pt 2):306-9. PMID: 26912516.
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    19. Mintzer S, French JA, Perucca E, Cramer JA, Messenheimer JA, Blum DE, Rogawski MA, Baulac M. Is a separate monotherapy indication warranted for antiepileptic drugs? Lancet Neurol. 2015 Dec; 14(12):1229-40. PMID: 26581972.
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    20. Desai R, Savechenkov PY, Zolkowska D, Ge RL, Rogawski MA, Bruzik KS, Forman SA, Raines DE, Miller KW. Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the a1 ß3 ?2L GABAA receptor account for their in vivo effects. J Physiol. 2015 Nov 15; 593(22):4943-61. PMID: 26378885.
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    21. Kazdoba TM, Hagerman RJ, Zolkowska D, Rogawski MA, Crawley JN. Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism. Psychopharmacology (Berl). 2016 Jan; 233(2):309-23. PMID: 26525567.
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    22. Irwin RW, Solinsky CM, Loya CM, Salituro FG, Rodgers KE, Bauer G, Rogawski MA, Brinton RD. Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. PLoS One. 2015; 10(6):e0128313. PMID: 26039057.
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    23. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. PMID: 25882826.
      View in: PubMed
    24. Coleman N, Nguyen HM, Cao Z, Brown BM, Jenkins DP, Zolkowska D, Chen YJ, Tanaka BS, Goldin AL, Rogawski MA, Pessah IN, Wulff H. The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics. 2015 Jan; 12(1):234-49. PMID: 25256961.
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    25. Rogawski MA, Tofighy A, White HS, Matagne A, Wolff C. Current understanding of the mechanism of action of the antiepileptic drug lacosamide. Epilepsy Res. 2015 Feb; 110:189-205. PMID: 25616473.
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    26. Broomall E, Natale JE, Grimason M, Goldstein J, Smith CM, Chang C, Kanes S, Rogawski MA, Wainwright MS. Pediatric super-refractory status epilepticus treated with allopregnanolone. Ann Neurol. 2014 Dec; 76(6):911-5. PMID: 25363147.
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    27. Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicol Appl Pharmacol. 2014 Dec 01; 281(2):185-94. PMID: 25448683.
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    28. Chen CY, Matt L, Hell JW, Rogawski MA. Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. PLoS One. 2014; 9(9):e108021. PMID: 25229608.
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    29. Fritsch B, Reis J, Gasior M, Kaminski RM, Rogawski MA. Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis. J Neurosci. 2014 Apr 23; 34(17):5765-75. PMID: 24760837.
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    30. Zolkowska D, Dhir A, Krishnan K, Covey DF, Rogawski MA. Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms. Psychopharmacology (Berl). 2014 Sep; 231(17):3325-32. PMID: 24705905.
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    31. Kaminski RM, Rogawski MA, Klitgaard H. The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments. Neurotherapeutics. 2014 Apr; 11(2):385-400. PMID: 24671870.
      View in: PubMed
    32. Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One. 2013; 8(12):e80922. PMID: 24349022.
      View in: PubMed
    33. Rogawski MA, Loya CM, Reddy K, Zolkowska D, Lossin C. Neuroactive steroids for the treatment of status epilepticus. Epilepsia. 2013 Sep; 54 Suppl 6:93-8. PMID: 24001085.
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    34. Galanopoulou AS, Kokaia M, Loeb JA, Nehlig A, Pitkänen A, Rogawski MA, Staley KJ, Whittemore VH, Dudek FE. Epilepsy therapy development: technical and methodologic issues in studies with animal models. Epilepsia. 2013 Aug; 54 Suppl 4:13-23. PMID: 23909850.
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    35. Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. Issues related to development of new antiseizure treatments. Epilepsia. 2013 Aug; 54 Suppl 4:24-34. PMID: 23909851.
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    36. Bröer S, Zolkowska D, Gernert M, Rogawski MA. Proconvulsant actions of intrahippocampal botulinum neurotoxin B in the rat. Neuroscience. 2013 Nov 12; 252:253-61. PMID: 23906638.
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    37. Dhir A, Zolkowska D, Rogawski MA. Seizure protection by intrapulmonary delivery of midazolam in mice. Neuropharmacology. 2013 Oct; 73:425-31. PMID: 23774136.
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    38. Gasior M, Tang R, Rogawski MA. Long-lasting attenuation of amygdala-kindled seizures after convection-enhanced delivery of botulinum neurotoxins a and B into the amygdala in rats. J Pharmacol Exp Ther. 2013 Sep; 346(3):528-34. PMID: 23772062.
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    39. Rogawski MA. The intrinsic severity hypothesis of pharmacoresistance to antiepileptic drugs. Epilepsia. 2013 May; 54 Suppl 2:33-40. PMID: 23646969.
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    40. Devinsky O, Vezzani A, Najjar S, De Lanerolle NC, Rogawski MA. Glia and epilepsy: excitability and inflammation. Trends Neurosci. 2013 Mar; 36(3):174-84. PMID: 23298414.
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    41. Rogawski MA, Hanada T. Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist. Acta Neurol Scand Suppl. 2013; (197):19-24. PMID: 23480152.
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    42. Rogawski MA. AMPA receptors as a molecular target in epilepsy therapy. Acta Neurol Scand Suppl. 2013; (197):9-18. PMID: 23480151.
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    43. Löscher W, Rogawski MA. How theories evolved concerning the mechanism of action of barbiturates. Epilepsia. 2012 Dec; 53 Suppl 8:12-25. PMID: 23205959.
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    44. Lossin C, Nam TS, Shahangian S, Rogawski MA, Choi SY, Kim MK, Sunwoo IN. Altered fast and slow inactivation of the N440K Nav1.4 mutant in a periodic paralysis syndrome. Neurology. 2012 Sep 04; 79(10):1033-40. PMID: 22914841.
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    45. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca²? dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. PMID: 22889812.
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    46. French JA, Krauss GL, Biton V, Squillacote D, Yang H, Laurenza A, Kumar D, Rogawski MA. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology. 2012 Aug 07; 79(6):589-96. PMID: 22843280.
      View in: PubMed
    47. Lossin C, Shi X, Rogawski MA, Hirose S. Compromised function in the Na(v)1.2 Dravet syndrome mutation R1312T. Neurobiol Dis. 2012 Sep; 47(3):378-84. PMID: 22677033.
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    48. Dhir A, Rogawski MA. Role of neurosteroids in the anticonvulsant activity of midazolam. Br J Pharmacol. 2012 Apr; 165(8):2684-91. PMID: 22014182.
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    49. Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 01; 21(13):2923-35. PMID: 22466801.
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    50. Dhir A, Lossin C, Rogawski MA. Propofol hemisuccinate suppresses cortical spreading depression. Neurosci Lett. 2012 Apr 11; 514(1):67-70. PMID: 22390898.
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    51. Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther. 2012 May; 341(2):435-46. PMID: 22328574.
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    52. Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handb Clin Neurol. 2012; 108:663-81. PMID: 22939059.
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    53. Rogawski MA, Federoff HJ. Disclosure of clinical trial results when product development is abandoned. Sci Transl Med. 2011 Sep 28; 3(102):102cm29. PMID: 21957167.
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    54. Stafstrom CE, Arnason BG, Baram TZ, Catania A, Cortez MA, Glauser TA, Pranzatelli MR, Riikonen R, Rogawski MA, Shinnar S, Swann JW. Treatment of infantile spasms: emerging insights from clinical and basic science perspectives. J Child Neurol. 2011 Nov; 26(11):1411-21. PMID: 21719797.
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    55. Kaminski RM, Rogawski MA. 11ß-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis. Neuropharmacology. 2011 Jul-Aug; 61(1-2):133-7. PMID: 21458468.
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    56. Rogawski MA. Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Curr. 2011 Mar; 11(2):56-63. PMID: 21686307.
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    57. Rogawski MA. A new policy for disclosure of competing interests. Epilepsy Curr. 2011 Jan; 11(1):7-8. PMID: 21461259.
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    58. Bergey GK, Rogawski MA, French J, Stafstrom CE. To Our Readers and the AES Membership. Epilepsy Curr. 2011 Jan; 11(1):7. PMID: 21461258.
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    59. Noebels JL, Avoli M, Rogawski M, Olsen R, Delgado-Escueta AV. "Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia. 2010 Dec; 51 Suppl 5:1-5. PMID: 21208201.
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    60. Rogawski MA. Neurosteroids on the epilepsy chessboard-keeping seizures in check. Epilepsy Curr. 2010 Nov; 10(6):161-3. PMID: 21157546.
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    61. Dhir A, Zolkowska D, Murphy RB, Rogawski MA. Seizure protection by intrapulmonary delivery of propofol hemisuccinate. J Pharmacol Exp Ther. 2011 Jan; 336(1):215-22. PMID: 20837991.
      View in: PubMed
    62. Gasior M, Yankura J, Hartman AL, French A, Rogawski MA. Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. Epilepsia. 2010 Aug; 51(8):1385-94. PMID: 20491877.
      View in: PubMed
    63. Reddy DS, Rogawski MA. Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model. Epilepsy Res. 2010 May; 89(2-3):254-60. PMID: 20172694.
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    64. Reddy DS, Rogawski MA. Neurosteroids as endogenous regulators of seizure susceptibility and use in the treatment of epilepsy. Epilepsia. 2010; 51(Suppl 5):84. PMID: 25147407.
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    65. Schachter SC, Guttag J, Schiff SJ, Schomer DL. Advances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit. Epilepsy Behav. 2009 Sep; 16(1):3-46. PMID: 19780225.
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    66. Fritsch B, Stott JJ, Joelle Donofrio J, Rogawski MA. Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. Epilepsia. 2010 Jan; 51(1):108-17. PMID: 19682025.
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    67. Runyon SP, Orr M, Navarro HA, Kepler JA, Rogawski MA, Kaminski RM, Cook CE. 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities. Eur J Pharmacol. 2009 Sep 01; 617(1-3):68-73. PMID: 19577558.
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    68. Fritsch B, Qashu F, Figueiredo TH, Aroniadou-Anderjaska V, Rogawski MA, Braga MF. Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis. Neuroscience. 2009 Sep 29; 163(1):415-29. PMID: 19540312.
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    69. Braga MF, Aroniadou-Anderjaska V, Li H, Rogawski MA. Topiramate reduces excitability in the basolateral amygdala by selectively inhibiting GluK1 (GluR5) kainate receptors on interneurons and positively modulating GABAA receptors on principal neurons. J Pharmacol Exp Ther. 2009 Aug; 330(2):558-66. PMID: 19417176.
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    70. Rogawski MA, Holmes GL. Nontraditional epilepsy treatment approaches. Neurotherapeutics. 2009 Apr; 6(2):213-7. PMID: 19332312.
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    71. Rogawski MA. Convection-enhanced delivery in the treatment of epilepsy. Neurotherapeutics. 2009 Apr; 6(2):344-51. PMID: 19332329.
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    72. Reddy DS, Rogawski MA. Neurosteroid replacement therapy for catamenial epilepsy. Neurotherapeutics. 2009 Apr; 6(2):392-401. PMID: 19332335.
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    73. Biagini G, Longo D, Baldelli E, Zoli M, Rogawski MA, Bertazzoni G, Avoli M. Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia. 2009 Jan; 50 Suppl 1:53-8. PMID: 19125849.
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    74. Rogawski MA, Johnson MR. Intrinsic severity as a determinant of antiepileptic drug refractoriness. Epilepsy Curr. 2008 Sep-Oct; 8(5):127-30. PMID: 18852835.
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    75. Rogawski MA, Bazil CW. New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels. Curr Neurol Neurosci Rep. 2008 Jul; 8(4):345-52. PMID: 18590620.
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    76. Rogawski MA. Brivaracetam: a rational drug discovery success story. Br J Pharmacol. 2008 Aug; 154(8):1555-7. PMID: 18552880.
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    77. Rogawski MA. Common pathophysiologic mechanisms in migraine and epilepsy. Arch Neurol. 2008 Jun; 65(6):709-14. PMID: 18541791.
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    78. Gasior M, Hartman AL, Rogawski MA. The anticonvulsant activity of acetone does not depend upon its metabolites. Epilepsia. 2008 May; 49(5):936-7. PMID: 18454785.
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    79. Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry. 2008 Sep; 13(9):858-72. PMID: 18332879.
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    80. Hartman AL, Lyle M, Rogawski MA, Gasior M. Efficacy of the ketogenic diet in the 6-Hz seizure test. Epilepsia. 2008 Feb; 49(2):334-9. PMID: 18070095.
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    81. Dudek FE, Rogawski MA. Calcium currents burst back: a possible role for dendrites in epileptogenesis. Epilepsy Curr. 2007 Sep-Oct; 7(5):140-1. PMID: 17998977.
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    82. Gasior M, White NA, Rogawski MA. Prolonged attenuation of amygdala-kindled seizure measures in rats by convection-enhanced delivery of the N-type calcium channel antagonists omega-conotoxin GVIA and omega-conotoxin MVIIA. J Pharmacol Exp Ther. 2007 Nov; 323(2):458-68. PMID: 17717191.
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    83. Hartman AL, Gasior M, Vining EP, Rogawski MA. The neuropharmacology of the ketogenic diet. Pediatr Neurol. 2007 May; 36(5):281-92. PMID: 17509459.
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    84. Gasior M, French A, Joy MT, Tang RS, Hartman AL, Rogawski MA. The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid. Epilepsia. 2007 Apr; 48(4):793-800. PMID: 17386058.
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    85. Rho JM, Rogawski MA. The ketogenic diet: stoking the powerhouse of the cell. Epilepsy Curr. 2007 Mar-Apr; 7(2):58-60. PMID: 17505556.
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    86. Meldrum BS, Rogawski MA. Molecular targets for antiepileptic drug development. Neurotherapeutics. 2007 Jan; 4(1):18-61. PMID: 17199015.
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    87. Rogawski MA. Point-counterpoint: Do interictal spikes trigger seizures or protect against them? Epilepsy Curr. 2006 Nov-Dec; 6(6):197-8. PMID: 17260058.
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    88. Rogawski MA, Suber P. Support for the NIH public access policy. Science. 2006 Sep 15; 313(5793):1572. PMID: 16973859.
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    89. Gasior M, Rogawski MA, Hartman AL. Neuroprotective and disease-modifying effects of the ketogenic diet. Behav Pharmacol. 2006 Sep; 17(5-6):431-9. PMID: 16940764.
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    90. Motamedi GK, Salazar P, Smith EL, Lesser RP, Webber WR, Ortinski PI, Vicini S, Rogawski MA. Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models. Epilepsy Res. 2006 Aug; 70(2-3):200-10. PMID: 16815680.
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    91. Biagini G, Baldelli E, Longo D, Pradelli L, Zini I, Rogawski MA, Avoli M. Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy. Exp Neurol. 2006 Oct; 201(2):519-24. PMID: 16780839.
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    92. Rogawski MA. Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res. 2006 Jun; 69(3):273-94. PMID: 16621450.
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    93. Kaminski RM, Marini H, Ortinski PI, Vicini S, Rogawski MA. The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors. J Pharmacol Exp Ther. 2006 May; 317(2):694-703. PMID: 16415088.
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    94. Rogawski MA. Molecular targets versus models for new antiepileptic drug discovery. Epilepsy Res. 2006 Jan; 68(1):22-8. PMID: 16377151.
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    95. Rogawski MA. Update on the neurobiology of alcohol withdrawal seizures. Epilepsy Curr. 2005 Nov-Dec; 5(6):225-30. PMID: 16372057.
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    96. Rogawski MA. Astrocytes get in the act in epilepsy. Nat Med. 2005 Sep; 11(9):919-20. PMID: 16145568.
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    97. Gryder DS, Castaneda DC, Rogawski MA. Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala. J Neurochem. 2005 Sep; 94(6):1728-38. PMID: 16045445.
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    98. Kaminski RM, Marini H, Kim WJ, Rogawski MA. Anticonvulsant activity of androsterone and etiocholanolone. Epilepsia. 2005 Jun; 46(6):819-27. PMID: 15946323.
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    99. Dudek FE, Rogawski MA. Regulation of brain water: is there a role for aquaporins in epilepsy? Epilepsy Curr. 2005 May-Jun; 5(3):104-6. PMID: 16145616.
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    100. Winitsky SO, Gopal TV, Hassanzadeh S, Takahashi H, Gryder D, Rogawski MA, Takeda K, Yu ZX, Xu YH, Epstein ND. Adult murine skeletal muscle contains cells that can differentiate into beating cardiomyocytes in vitro. PLoS Biol. 2005 Apr; 3(4):e87. PMID: 15757365.
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    101. Reddy DS, O'Malley BW, Rogawski MA. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 2005 Jan; 48(1):14-24. PMID: 15617723.
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    102. Ivanov SV, Ward JM, Tessarollo L, McAreavey D, Sachdev V, Fananapazir L, Banks MK, Morris N, Djurickovic D, Devor-Henneman DE, Wei MH, Alvord GW, Gao B, Richardson JA, Minna JD, Rogawski MA, Lerman MI. Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene. Am J Pathol. 2004 Sep; 165(3):1007-18. PMID: 15331424.
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    103. Rogawski MA, Löscher W. The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. Nat Med. 2004 Jul; 10(7):685-92. PMID: 15229516.
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    104. Rogawski MA. What is the rationale for new treatment strategies in Alzheimer's disease? CNS Spectr. 2004 Jul; 9(7 Suppl 5):6-12. PMID: 15241294.
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    105. Kaminski RM, Livingood MR, Rogawski MA. Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. Epilepsia. 2004 Jul; 45(7):864-7. PMID: 15230714.
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    106. Rogawski MA, Löscher W. The neurobiology of antiepileptic drugs. Nat Rev Neurosci. 2004 Jul; 5(7):553-64. PMID: 15208697.
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    107. Kaminski RM, Banerjee M, Rogawski MA. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 2004 Jun; 46(8):1097-104. PMID: 15111016.
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    108. Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. J Pharmacol Exp Ther. 2004 Jul; 310(1):230-9. PMID: 14982969.
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    109. Gryder DS, Rogawski MA. Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons. J Neurosci. 2003 Aug 06; 23(18):7069-74. PMID: 12904467.
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    110. Salazar P, Tapia R, Rogawski MA. Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice. Epilepsy Res. 2003 Jun-Jul; 55(1-2):71-82. PMID: 12948618.
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    111. Pearl PL, Gibson KM, Acosta MT, Vezina LG, Theodore WH, Rogawski MA, Novotny EJ, Gropman A, Conry JA, Berry GT, Tuchman M. Clinical spectrum of succinic semialdehyde dehydrogenase deficiency. Neurology. 2003 May 13; 60(9):1413-7. PMID: 12743223.
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    112. Rogawski MA, Gryder D, Castaneda D, Yonekawa W, Banks MK, Lia H. GluR5 kainate receptors, seizures, and the amygdala. Ann N Y Acad Sci. 2003 Apr; 985:150-62. PMID: 12724156.
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    113. Rogawski MA. Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy. Ann Neurol. 2003 Mar; 53(3):288-91. PMID: 12601696.
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    114. Rogawski MA, Wenk GL. The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease. CNS Drug Rev. 2003; 9(3):275-308. PMID: 14530799.
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    115. Rogawski MA. Does P-glycoprotein play a role in pharmacoresistance to antiepileptic drugs? Epilepsy Behav. 2002 Dec; 3(6):493-495. PMID: 12609240.
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    116. Rogawski MA. Antiepileptogenesis by Deep Brain Stimulation. Epilepsy Curr. 2002 Sep; 2(5):153-154. PMID: 15309125.
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    117. Dudek FE, Rogawski MA. The Epileptic Neuron Redux. Epilepsy Curr. 2002 Sep; 2(5):151-152. PMID: 15309124.
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    118. Pace JR, Lonser RR, Kirkby RD, Jeffries N, Rogawski MA, Oldfield EH. Epileptiform activity extinguished by amygdala infusion of the neurotoxin ibotenate in a rat model of temporal lobe epilepsy. J Neurosurg. 2002 Aug; 97(2):450-4. PMID: 12186475.
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    119. Schmidt D, Rogawski MA. New strategies for the identification of drugs to prevent the development or progression of epilepsy. Epilepsy Res. 2002 Jun; 50(1-2):71-8. PMID: 12151119.
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    120. Reddy DS, Rogawski MA. Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. J Neurosci. 2002 May 01; 22(9):3795-805. PMID: 11978855.
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    121. Rogawski MA. New Evidence Supporting a Role for T-Type Ca(2+) Channels in Absence Epilepsy and in the Action of Ethosuximide. Epilepsy Curr. 2002 Mar; 2(2):57. PMID: 15309167.
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    122. Rogawski MA, Reddy DS. Neurosteroids and infantile spasms: the deoxycorticosterone hypothesis. Int Rev Neurobiol. 2002; 49:199-219. PMID: 12040893.
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    123. Basile AS, Koustova E, Ioan P, Rizzoli S, Rogawski MA, Usherwood PN. IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors. Neurobiol Dis. 2001 Dec; 8(6):1069-81. PMID: 11741402.
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    124. Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. Future directions for epilepsy research. Neurology. 2001 Nov 13; 57(9):1536-42. PMID: 11706087.
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    125. Li H, Chen A, Xing G, Wei ML, Rogawski MA. Kainate receptor-mediated heterosynaptic facilitation in the amygdala. Nat Neurosci. 2001 Jun; 4(6):612-20. PMID: 11369942.
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    126. Avoli M, Rogawski MA, Avanzini G. Generalized epileptic disorders: an update. Epilepsia. 2001 Apr; 42(4):445-57. PMID: 11440339.
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    127. Aroniadou-Anderjaska V, Post RM, Rogawski MA, Li H. Input-specific LTP and depotentiation in the basolateral amygdala. Neuroreport. 2001 Mar 05; 12(3):635-40. PMID: 11234779.
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    128. Reddy DS, Kim HY, Rogawski MA. Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. Epilepsia. 2001 Mar; 42(3):328-36. PMID: 11442149.
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    129. Reddy DS, Rogawski MA. Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. Epilepsia. 2001 Mar; 42(3):337-44. PMID: 11442150.
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    130. Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS. LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. J Clin Invest. 2001 Mar; 107(6):737-44. PMID: 11254673.
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    131. Rogawski MA, Kurzman PS, Yamaguchi SI, Li H. Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse. Neuropharmacology. 2001; 40(1):28-35. PMID: 11077068.
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    132. Reddy DS, Rogawski MA. Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. J Pharmacol Exp Ther. 2000 Dec; 295(3):1241-8. PMID: 11082461.
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    133. Reddy DS, Rogawski MA. Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy. J Pharmacol Exp Ther. 2000 Sep; 294(3):909-15. PMID: 10945840.
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    134. Rogawski MA. KCNQ2/KCNQ3 K+ channels and the molecular pathogenesis of epilepsy: implications for therapy. Trends Neurosci. 2000 Sep; 23(9):393-8. PMID: 10941184.
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    135. Rogawski MA, Wasterlain CG, Mazarati AM. Re: Mazarati et al. "...clinically available [antiepileptic drug] with a moderate affinity for the glycine site of the N-methyl-D-aspartate (NMDA) receptor". Epilepsia. 2000 Jul; 41(7):918-9. PMID: 10897169.
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    136. Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4926-31. PMID: 10781100.
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    137. Harty TP, Rogawski MA. Felbamate block of recombinant N-methyl-D-aspartate receptors: selectivity for the NR2B subunit. Epilepsy Res. 2000 Mar; 39(1):47-55. PMID: 10690753.
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    138. Rogawski MA. Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability. Amino Acids. 2000; 19(1):133-49. PMID: 11026482.
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    139. Kokate TG, Juhng KN, Kirkby RD, Llamas J, Yamaguchi S, Rogawski MA. Convulsant actions of the neurosteroid pregnenolone sulfate in mice. Brain Res. 1999 Jun 12; 831(1-2):119-24. PMID: 10411990.
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    140. Juhng KN, Kokate TG, Yamaguchi S, Kim BY, Rogowski RS, Blaustein MP, Rogawski MA. Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha). Epilepsy Res. 1999 Apr; 34(2-3):177-86. PMID: 10210033.
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    141. Kokate TG, Banks MK, Magee T, Yamaguchi S, Rogawski MA. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. J Pharmacol Exp Ther. 1999 Feb; 288(2):679-84. PMID: 9918575.
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    142. Rogawski MA, Donevan SD. AMPA receptors in epilepsy and as targets for antiepileptic drugs. Adv Neurol. 1999; 79:947-63. PMID: 10514878.
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    143. Donevan SD, Rogawski MA. Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines. Neuroscience. 1998 Dec; 87(3):615-29. PMID: 9758228.
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    144. Kokate TG, Yamaguchi S, Pannell LK, Rajamani U, Carroll DM, Grossman AB, Rogawski MA. Lack of anticonvulsant tolerance to the neuroactive steroid pregnanolone in mice. J Pharmacol Exp Ther. 1998 Nov; 287(2):553-8. PMID: 9808680.
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    145. Li H, Rogawski MA. GluR5 kainate receptor mediated synaptic transmission in rat basolateral amygdala in vitro. Neuropharmacology. 1998 Oct-Nov; 37(10-11):1279-86. PMID: 9849665.
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    146. Grauert M, Rho JM, Subramaniam S, Rogawski MA. N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL. J Pharmacol Exp Ther. 1998 May; 285(2):767-76. PMID: 9580625.
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    147. Li H, Weiss SR, Chuang DM, Post RM, Rogawski MA. Bidirectional synaptic plasticity in the rat basolateral amygdala: characterization of an activity-dependent switch sensitive to the presynaptic metabotropic glutamate receptor antagonist 2S-alpha-ethylglutamic acid. J Neurosci. 1998 Mar 01; 18(5):1662-70. PMID: 9464991.
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    148. Rogawski MA. Mechanism-specific pathways for new antiepileptic drug discovery. Adv Neurol. 1998; 76:11-27. PMID: 9408460.
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    149. Rho JM, Donevan SD, Rogawski MA. Barbiturate-like actions of the propanediol dicarbamates felbamate and meprobamate. J Pharmacol Exp Ther. 1997 Mar; 280(3):1383-91. PMID: 9067327.
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    150. Rho JM, Donevan SD, Rogawski MA. Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons. J Physiol. 1996 Dec 01; 497 ( Pt 2):509-22. PMID: 8961191.
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    151. Rogowski RS, Collins JH, O'Neill TJ, Gustafson TA, Werkman TR, Rogawski MA, Tenenholz TC, Weber DJ, Blaustein MP. Three new toxins from the scorpion Pandinus imperator selectively block certain voltage-gated K+ channels. Mol Pharmacol. 1996 Nov; 50(5):1167-77. PMID: 8913348.
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    152. Chen K, Kokate TG, Donevan SD, Carroll FI, Rogawski MA. Ibogaine block of the NMDA receptor: in vitro and in vivo studies. Neuropharmacology. 1996 Apr; 35(4):423-31. PMID: 8793904.
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    153. Donevan SD, Rogawski MA. Multiple actions of arylalkylamine arthropod toxins on the N-methyl-D-aspartate receptor. Neuroscience. 1996 Jan; 70(2):361-75. PMID: 8848146.
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    154. Grant KA, Colombo G, Grant J, Rogawski MA. Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists. Neuropharmacology. 1996; 35(12):1709-19. PMID: 9076750.
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    155. Kokate TG, Cohen AL, Karp E, Rogawski MA. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology. 1996; 35(8):1049-56. PMID: 9121607.
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    156. Hough CJ, Irwin RP, Gao XM, Rogawski MA, Chuang DM. Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells. J Pharmacol Exp Ther. 1996 Jan; 276(1):143-9. PMID: 8558424.
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    157. Poling JS, Vicini S, Rogawski MA, Salem N. Docosahexaenoic acid block of neuronal voltage-gated K+ channels: subunit selective antagonism by zinc. Neuropharmacology. 1996; 35(7):969-82. PMID: 8938727.
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    158. Poling JS, Rogawski MA, Salem N, Vicini S. Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. Neuropharmacology. 1996; 35(7):983-91. PMID: 8938728.
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    159. Subramaniam S, Donevan SD, Rogawski MA. Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite. J Pharmacol Exp Ther. 1996 Jan; 276(1):161-8. PMID: 8558426.
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    160. Levitan IB, Rogawski MA. Potassium channels. Neuropharmacology. 1996; 35(7):759. PMID: 8938708.
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    161. Lapin IP, Rogawski MA. Effects of D1 and D2 dopamine receptor antagonists and catecholamine depleting agents on the locomotor stimulation induced by dizocilpine in mice. Behav Brain Res. 1995 Oct; 70(2):145-51. PMID: 8561905.
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    162. Donevan SD, Rogawski MA. Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9298-302. PMID: 7568121.
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    163. Rogawski MA, Le DQ, Uyakul D, Pannell LK, Subramaniam S, Yamaguchi S, Kokate TG. Anticonvulsant efficacy of ADCI (5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine) after acute and chronic dosing in mice. Epilepsia. 1995 Jun; 36(6):566-71. PMID: 7555968.
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    164. Subramaniam S, Rho JM, Penix L, Donevan SD, Fielding RP, Rogawski MA. Felbamate block of the N-methyl-D-aspartate receptor. J Pharmacol Exp Ther. 1995 May; 273(2):878-86. PMID: 7752093.
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    165. Mattia D, Nagao T, Rogawski MA, Avoli M. Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice. Neuropharmacology. 1994 Dec; 33(12):1515-22. PMID: 7760973.
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    166. Irwin RP, Lin SZ, Rogawski MA, Purdy RH, Paul SM. Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies. J Pharmacol Exp Ther. 1994 Nov; 271(2):677-82. PMID: 7965782.
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    167. Donevan SD, Yamaguchi S, Rogawski MA. Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity. J Pharmacol Exp Ther. 1994 Oct; 271(1):25-9. PMID: 7525924.
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    168. Kokate TG, Svensson BE, Rogawski MA. Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. J Pharmacol Exp Ther. 1994 Sep; 270(3):1223-9. PMID: 7932175.
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    169. McRae KD. Riluzole in amyotrophic lateral sclerosis. N Engl J Med. 1994 Jul 28; 331(4):272-3; author reply 273-4. PMID: 8015578.
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    170. Svensson BE, Werkman TR, Rogawski MA. Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology. 1994 Jun; 33(6):795-804. PMID: 7936117.
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    171. Rho JM, Donevan SD, Rogawski MA. Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and gamma-aminobutyric acidA receptors. Ann Neurol. 1994 Feb; 35(2):229-34. PMID: 8109904.
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    172. Goodman CB, Thomas DN, Pert A, Emilien B, Cadet JL, Carroll FI, Blough BE, Mascarella SW, Rogawski MA, Subramaniam S. RTI-4793-14, a new ligand with high affinity and selectivity for the (+)-MK801-insensitive [3H]1-]1-(2-thienyl)cyclohexyl]piperidine binding site (PCP site 2) of guinea pig brain. Synapse. 1994 Jan; 16(1):59-65. PMID: 8134901.
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    173. Subramaniam S, Donevan SD, Rogawski MA. Hydrophobic interactions of n-alkyl diamines with the N-methyl-D-aspartate receptor: voltage-dependent and -independent blocking sites. Mol Pharmacol. 1994 Jan; 45(1):117-24. PMID: 8302270.
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    174. Rogawski MA. Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines. Trends Pharmacol Sci. 1993 Sep; 14(9):325-31. PMID: 7504360.
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    175. Werkman TR, Gustafson TA, Rogowski RS, Blaustein MP, Rogawski MA. Tityustoxin-K alpha, a structurally novel and highly potent K+ channel peptide toxin, interacts with the alpha-dendrotoxin binding site on the cloned Kv1.2 K+ channel. Mol Pharmacol. 1993 Aug; 44(2):430-6. PMID: 8355670.
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    176. ffrench-Mullen JM, Barker JL, Rogawski MA. Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current. J Neurosci. 1993 Aug; 13(8):3211-21. PMID: 8101867.
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    177. Yamaguchi S, Donevan SD, Rogawski MA. Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models. Epilepsy Res. 1993 Jul; 15(3):179-84. PMID: 7693450.
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    178. Donevan SD, Rogawski MA. GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron. 1993 Jan; 10(1):51-9. PMID: 7678966.
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    179. Subramaniam S, Donevan SD, Rogawski MA. 1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism. Neurosci Lett. 1992 Dec 07; 147(2):213-6. PMID: 1283458.
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    180. Ffrench-Mullen JM, Rogawski MA. Phencyclidine block of calcium current in isolated guinea-pig hippocampal neurones. J Physiol. 1992 Oct; 456:85-105. PMID: 1338108.
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    181. Werkman TR, Kawamura T, Yokoyama S, Higashida H, Rogawski MA. Charybdotoxin, dendrotoxin and mast cell degranulating peptide block the voltage-activated K+ current of fibroblast cells stably transfected with NGK1 (Kv1.2) K+ channel complementary DNA. Neuroscience. 1992 Oct; 50(4):935-46. PMID: 1280351.
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    182. Rogawski MA. The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report. Drugs. 1992 Sep; 44(3):279-92. PMID: 1382930.
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    183. Pace JR, Martin BM, Paul SM, Rogawski MA. High concentrations of neutral amino acids activate NMDA receptor currents in rat hippocampal neurons. Neurosci Lett. 1992 Jul 06; 141(1):97-100. PMID: 1324446.
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    184. Irwin RP, Maragakis NJ, Rogawski MA, Purdy RH, Farb DH, Paul SM. Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons. Neurosci Lett. 1992 Jul 06; 141(1):30-4. PMID: 1387199.
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    185. Donevan SD, Jones SM, Rogawski MA. Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons. Mol Pharmacol. 1992 Apr; 41(4):727-35. PMID: 1373801.
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    186. Coleman MH, Yamaguchi S, Rogawski MA. Protection against dendrotoxin-induced clonic seizures in mice by anticonvulsant drugs. Brain Res. 1992 Mar 13; 575(1):138-42. PMID: 1504773.
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    187. Yamaguchi S, Rogawski MA. Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice. Epilepsy Res. 1992 Mar; 11(1):9-16. PMID: 1563341.
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    188. Grant KA, Snell LD, Rogawski MA, Thurkauf A, Tabakoff B. Comparison of the effects of the uncompetitive N-methyl-D-aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine (ADCI) with its structural analogs dizocilpine (MK-801) and carbamazepine on ethanol withdrawal seizures. J Pharmacol Exp Ther. 1992 Mar; 260(3):1017-22. PMID: 1545374.
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    189. Blake PA, Yamaguchi S, Thurkauf A, Rogawski MA. Anticonvulsant 1-phenylcycloalkylamines: two analogues with low motor toxicity when orally administered. Epilepsia. 1992 Jan-Feb; 33(1):188-94. PMID: 1531130.
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    190. Lapin IP, Rogawski MA. Muscarinic antagonists attenuate dizocilpine-induced hypermotility in mice. Life Sci. 1992; 50(9):PL59-64. PMID: 1740967.
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    191. Porter RJ, Rogawski MA. New antiepileptic drugs: from serendipity to rational discovery. Epilepsia. 1992; 33 Suppl 1:S1-6. PMID: 1379532.
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    192. Porter RJ, Rogawski MA. Theoretical and practical considerations concerning the use of NMDA antagonists in the treatment of the epilepsies. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:697A-698A. PMID: 1386786.
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    193. Rogawski MA, Yamaguchi S, Jones SM, Rice KC, Thurkauf A, Monn JA. Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine. J Pharmacol Exp Ther. 1991 Oct; 259(1):30-7. PMID: 1920122.
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    194. Wang XJ, Rinzel J, Rogawski MA. A model of the T-type calcium current and the low-threshold spike in thalamic neurons. J Neurophysiol. 1991 Sep; 66(3):839-50. PMID: 1661326.
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    195. Politi DM, Rogawski MA. Glyburide-sensitive K+ channels in cultured rat hippocampal neurons: activation by cromakalim and energy-depleting conditions. Mol Pharmacol. 1991 Aug; 40(2):308-15. PMID: 1715018.
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    196. Hershkowitz N, Rogawski MA. Tetrahydroaminoacridine block of N-methyl-D-aspartate-activated cation channels in cultured hippocampal neurons. Mol Pharmacol. 1991 May; 39(5):592-8. PMID: 1709720.
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    197. Rogawski MA, Porter RJ. Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol Rev. 1990 Sep; 42(3):223-86. PMID: 2217531.
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    198. Thurkauf A, de Costa B, Yamaguchi S, Mattson MV, Jacobson AE, Rice KC, Rogawski MA. Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. J Med Chem. 1990 May; 33(5):1452-8. PMID: 2329567.
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    199. Rogawski MA, Hershkowitz N, Politi DM, Suzuki S, Thurkauf A, Yamaguchi S. Novel research strategies for antiepileptic therapy. Prog Clin Biol Res. 1990; 361:91-111. PMID: 2290852.
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    200. ffrench-Mullen JM, Rogawski MA. Interaction of phencyclidine with voltage-dependent potassium channels in cultured rat hippocampal neurons: comparison with block of the NMDA receptor-ionophore complex. J Neurosci. 1989 Nov; 9(11):4051-61. PMID: 2555461.
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    201. Hershkowitz N, Rogawski MA. Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. Br J Pharmacol. 1989 Nov; 98(3):1005-13. PMID: 2556198.
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    202. Suzuki S, Rogawski MA. T-type calcium channels mediate the transition between tonic and phasic firing in thalamic neurons. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7228-32. PMID: 2550936.
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    203. Politi DM, Suzuki S, Rogawski MA. BRL 34915 (cromakalim) enhances voltage-dependent K+ current in cultured rat hippocampal neurons. Eur J Pharmacol. 1989 Sep 01; 168(1):7-14. PMID: 2583232.
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    204. Rogawski MA, Thurkauf A, Yamaguchi S, Rice KC, Jacobson AE, Mattson MV. Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline. J Pharmacol Exp Ther. 1989 Jun; 249(3):708-12. PMID: 2659775.
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    205. Rogawski MA. Aminopyridines enhance opening of calcium-activated potassium channels in GH3 anterior pituitary cells. Mol Pharmacol. 1989 Apr; 35(4):458-68. PMID: 2704369.
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    206. Siegel JM, Rogawski MA. A function for REM sleep: regulation of noradrenergic receptor sensitivity. Brain Res. 1988 Nov; 472(3):213-33. PMID: 3066435.
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    207. Mollard P, Vacher P, Rogawski MA, Dufy B. Vasopressin enhances a calcium current in human ACTH-secreting pituitary adenoma cells. FASEB J. 1988 Oct; 2(13):2907-12. PMID: 2844618.
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    208. Rogawski MA. Transient outward current (IA) in clonal anterior pituitary cells: blockade by aminopyridine analogs. Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug; 338(2):125-32. PMID: 3185742.
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    209. Rogawski MA, Pieniek M, Suzuki S, ffrench-Mullen JM. Phencyclidine selectively blocks the sustained voltage-dependent potassium conductance in PC12 cells. Brain Res. 1988 Jul 19; 456(1):38-48. PMID: 2457411.
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    210. ffrench-Mullen JM, Rogawski MA, Barker JL. Phencyclidine at low concentrations selectively blocks the sustained but not the transient voltage-dependent potassium current in cultured hippocampal neurons. Neurosci Lett. 1988 Jun 07; 88(3):325-30. PMID: 3386879.
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    211. Rogawski MA, Inoue K, Suzuki S, Barker JL. A slow calcium-dependent chloride conductance in clonal anterior pituitary cells. J Neurophysiol. 1988 Jun; 59(6):1854-70. PMID: 3404208.
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    212. Palopoli JJ, Waxman J. Colchicine neuropathy or vitamin B12 deficiency neuropathy? N Engl J Med. 1987 Nov 12; 317(20):1290-1. PMID: 2823139.
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    213. Rogawski MA. Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons. Eur J Pharmacol. 1987 Oct 06; 142(1):169-72. PMID: 2446884.
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    214. Mollard P, Vacher P, Guerin J, Rogawski MA, Dufy B. Electrical properties of cultured human adrenocorticotropin-secreting adenoma cells: effects of high K+, corticotropin-releasing factor, and angiotensin II. Endocrinology. 1987 Jul; 121(1):395-405. PMID: 3036472.
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    215. Kuncl RW, Duncan G, Watson D, Alderson K, Rogawski MA, Peper M. Colchicine myopathy and neuropathy. N Engl J Med. 1987 Jun 18; 316(25):1562-8. PMID: 3035372.
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    216. Rogawski MA. Single voltage-dependent potassium channels in cultured rat hippocampal neurons. J Neurophysiol. 1986 Aug; 56(2):481-93. PMID: 2428951.
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    217. Rogawski MA, Beinfeld MC, Hays SE, Hökfelt T, Skirboll LR. Cholecystokinin and cultured spinal neurons. Immunohistochemistry, receptor binding, and neurophysiology. Ann N Y Acad Sci. 1985; 448:403-12. PMID: 2992347.
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    218. Segal M, Rogawski MA, Barker JL. A transient potassium conductance regulates the excitability of cultured hippocampal and spinal neurons. J Neurosci. 1984 Feb; 4(2):604-9. PMID: 6699688.
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    219. Rogawski MA. Transdermal scopolamine and sialorrhea. Arch Neurol. 1984 Jan; 41(1):15. PMID: 6689882.
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    220. Barker JL, Dufy B, Owen DG, Rogawski MA. Electrophysiological studies of peptide actions on the excitability of cultured nerve and pituitary cells. Clin Exp Hypertens A. 1984; 6(10-11):1701-16. PMID: 6152408.
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    221. Rogawski MA, Barker JL. Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons. Brain Res. 1983 Nov 28; 280(1):180-5. PMID: 6652477.
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    222. Rogawski MA, Aghajanian GK. Activation of lateral geniculate neurons by locus coeruleus or dorsal noradrenergic bundle stimulation: selective blockade by the alpha 1-adrenoceptor antagonist prazosin. Brain Res. 1982 Oct 28; 250(1):31-9. PMID: 7139319.
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    223. Rogawski MA. Cholecystokinin octapeptide: effects on the excitability of cultured spinal neurons. Peptides. 1982 May-Jun; 3(3):545-51. PMID: 6126867.
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    224. Rogawski MA, Aghajanian GK. Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. J Neurosci. 1981 Oct; 1(10):1148-54. PMID: 6793698.
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    225. Rogawski MA, Aghajanian GK. Modulation of lateral geniculate neurone excitability by noradrenaline microiontophoresis or locus coeruleus stimulation. Nature. 1980 Oct 23; 287(5784):731-4. PMID: 6253811.
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    226. Rogawski MA, Aghajanian GK. Norepinephrine and serotonin: opposite effects on the activity of lateral geniculate neurons evoked by optic pathway stimulation. Exp Neurol. 1980 Sep; 69(3):678-94. PMID: 7409069.
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    227. Rogawski MA, Aghajanian GK. Activation of lateral geniculate neurons by norepinephrine: mediation by an alpha-adrenergic receptor. Brain Res. 1980 Jan 27; 182(2):345-59. PMID: 6101983.
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    228. Rogawski MA, Aghajanian GK. Response of central monoaminergic neurons to lisuride: comparison with LSD. Life Sci. 1979 Apr 02; 24(14):1289-97. PMID: 470543.
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    229. Rogawski MA, Roth RH, Aghajanian GK. Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase. J Neurochem. 1979 Apr; 32(4):1219-26. PMID: 285213.
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    230. Rogawski MA, Goodrich JT, Gershon MD, Touloukian RJ. Hirschsprung's disease: absence of serotonergic neurons in the aganglionic colon. J Pediatr Surg. 1978 Dec; 13(6D):608-15. PMID: 731360.
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    231. Rogawski MA, Funderburk SJ, Cederbaum SD. Oculocutaneous albinism and mental disorder. A report of two autistic boys. Hum Hered. 1978; 28(2):81-5. PMID: 413782.
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    232. Iversen LL, Rogawski MA, Miller RJ. Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum. Mol Pharmacol. 1976 Mar; 12(2):251-62. PMID: 4724.
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    233. Iversen LL, Miller RJ, Rogawski M. Proceedings:Pre- and postsynaptic actions of neuroleptic drugs. Br J Pharmacol. 1975 Oct; 55(2):297P-298P. PMID: 1201424.
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    234. Rogawski MA, Knapp S, MAndell AJ. Effects of ethanol on tryptophan hydroxylase activity from striate synaptosomes. Biochem Pharmacol. 1974 Jul 15; 23(14):1955-62. PMID: 4418689.
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    235. Hoeldtke R, Rogawski M, Wurtman RJ. Effect of selective destruction of central and peripheral catecholamine-containing neurones with 6-hydroxydopamine on catecholamine excretion in the rat. Br J Pharmacol. 1974 Feb; 50(2):265-70. PMID: 4425765.
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