Loading...

Gerhard Bauer

Title(s)Adjunct Professor, Hematology and Oncology
SchoolUniversity of California, Davis
Phone916-703-9300
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Showalter MR, Wancewicz B, Fiehn O, Archard JA, Clayton S, Wagner J, Deng P, Halmai J, Fink KD, Bauer G, Fury B, Perotti NH, Apperson M, Butters J, Belafsky P, Farwell G, Kuhn M, Nolta JA, Anderson JD. Primed mesenchymal stem cells package exosomes with metabolites associated with immunomodulation. Biochem Biophys Res Commun. 2019 May 14; 512(4):729-735. PMID: 30926165.
      View in: PubMed
    2. Yuan O, Lin C, Wagner J, Archard JA, Deng P, Halmai J, Bauer G, Fink KD, Fury B, Perotti NH, Walker JE, Pollock K, Apperson M, Butters J, Belafsky P, Farwell DG, Kuhn M, Nolta J, Anderson JD. Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion. Stem Cells Dev. 2019 Mar 15; 28(6):398-409. PMID: 30638129.
      View in: PubMed
    3. Fierro FA, Magner N, Beegle J, Dahlenburg H, Logan White J, Zhou P, Pepper K, Fury B, Coleal-Bergum DP, Bauer G, Gruenloh W, Annett G, Pifer C, Nolta JA. Mesenchymal stem/stromal cells genetically engineered to produce vascular endothelial growth factor for revascularization in wound healing and ischemic conditions. Transfusion. 2019 02; 59(S1):893-897. PMID: 30383901.
      View in: PubMed
    4. Bauer G, Elsallab M, Abou-El-Enein M. Concise Review: A Comprehensive Analysis of Reported Adverse Events in Patients Receiving Unproven Stem Cell-Based Interventions. Stem Cells Transl Med. 2018 09; 7(9):676-685. PMID: 30063299.
      View in: PubMed
    5. Lacher MD, Bauer G, Fury B, Graeve S, Fledderman EL, Petrie TD, Coleal-Bergum DP, Hackett T, Perotti NH, Kong YY, Kwok WW, Wagner JP, Wiseman CL, Williams WV. SV-BR-1-GM, a Clinically Effective GM-CSF-Secreting Breast Cancer Cell Line, Expresses an Immune Signature and Directly Activates CD4+ T Lymphocytes. Front Immunol. 2018; 9:776. PMID: 29867922.
      View in: PubMed
    6. Holley SM, Kamdjou T, Reidling JC, Fury B, Coleal-Bergum D, Bauer G, Thompson LM, Levine MS, Cepeda C. Therapeutic effects of stem cells in rodent models of Huntington's disease: Review and electrophysiological findings. CNS Neurosci Ther. 2018 04; 24(4):329-342. PMID: 29512295.
      View in: PubMed
    7. Reidling JC, Relaño-Ginés A, Holley SM, Ochaba J, Moore C, Fury B, Lau A, Tran AH, Yeung S, Salamati D, Zhu C, Hatami A, Cepeda C, Barry JA, Kamdjou T, King A, Coleal-Bergum D, Franich NR, LaFerla FM, Steffan JS, Blurton-Jones M, Meshul CK, Bauer G, Levine MS, Chesselet MF, Thompson LM. Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. Stem Cell Reports. 2018 01 09; 10(1):58-72. PMID: 29233555.
      View in: PubMed
    8. Abou-El-Enein M, Cathomen T, Ivics Z, June CH, Renner M, Schneider CK, Bauer G. Human Genome Editing in the Clinic: New Challenges in Regulatory Benefit-Risk Assessment. Cell Stem Cell. 2017 10 05; 21(4):427-430. PMID: 28985524.
      View in: PubMed
    9. Bauer G, Abou-El-Enein M, Kent A, Poole B, Forte M. The path to successful commercialization of cell and gene therapies: empowering patient advocates. Cytotherapy. 2017 02; 19(2):293-298. PMID: 27956199.
      View in: PubMed
    10. Park SS, Moisseiev E, Bauer G, Anderson JD, Grant MB, Zam A, Zawadzki RJ, Werner JS, Nolta JA. Advances in bone marrow stem cell therapy for retinal dysfunction. Prog Retin Eye Res. 2017 01; 56:148-165. PMID: 27784628.
      View in: PubMed
    11. Abou-El-Enein M, Bauer G, Medcalf N, Volk HD, Reinke P. Putting a price tag on novel autologous cellular therapies. Cytotherapy. 2016 08; 18(8):1056-1061. PMID: 27288308.
      View in: PubMed
    12. Anderson JD, Johansson HJ, Graham CS, Vesterlund M, Pham MT, Bramlett CS, Montgomery EN, Mellema MS, Bardini RL, Contreras Z, Hoon M, Bauer G, Fink KD, Fury B, Hendrix KJ, Chedin F, El-Andaloussi S, Hwang B, Mulligan MS, Lehtiö J, Nolta JA. Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling. Stem Cells. 2016 Mar; 34(3):601-13. PMID: 26782178.
      View in: PubMed
    13. Pollock K, Dahlenburg H, Nelson H, Fink KD, Cary W, Hendrix K, Annett G, Torrest A, Deng P, Gutierrez J, Nacey C, Pepper K, Kalomoiris S, D Anderson J, McGee J, Gruenloh W, Fury B, Bauer G, Duffy A, Tempkin T, Wheelock V, Nolta JA. Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models. Mol Ther. 2016 05; 24(5):965-77. PMID: 26765769.
      View in: PubMed
    14. Abou-El-Enein M, Bauer G, Reinke P. Gene therapy: a possible future standard for HIV care. Trends Biotechnol. 2015 Jul; 33(7):374-6. PMID: 26088914.
      View in: PubMed
    15. Correction: Allopregnanolone Preclinical Acute Pharmacokinetic and Pharmacodynamic Studies to Predict Tolerability and Efficacy for Alzheimer's Disease. PLoS One. 2015; 10(6):e0132210. PMID: 26121244.
      View in: PubMed
    16. Sheu J, Beltzer J, Fury B, Wilczek K, Tobin S, Falconer D, Nolta J, Bauer G. Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor. Mol Ther Methods Clin Dev. 2015; 2:15020. PMID: 26151065.
      View in: PubMed
    17. Cary WA, Hori CN, Pham MT, Nacey CA, McGee JL, Hamou M, Berman RF, Bauer G, Nolta JA, Waldau B. Efficient Generation of Induced Pluripotent Stem and Neural Progenitor Cells From Acutely Harvested Dura Mater Obtained During Ventriculoperitoneal Shunt Surgery. World Neurosurg. 2015 Nov; 84(5):1256-66.e1. PMID: 26074438.
      View in: PubMed
    18. Irwin RW, Solinsky CM, Loya CM, Salituro FG, Rodgers KE, Bauer G, Rogawski MA, Brinton RD. Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. PLoS One. 2015; 10(6):e0128313. PMID: 26039057.
      View in: PubMed
    19. Barclay SL, Yang Y, Zhang S, Fong R, Barraza A, Nolta JA, Torbett BE, Abedi M, Bauer G, Anderson JS. Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells. Stem Cells. 2015 Mar; 33(3):870-9. PMID: 25524029.
      View in: PubMed
    20. Park SS, Bauer G, Abedi M, Pontow S, Panorgias A, Jonnal R, Zawadzki RJ, Werner JS, Nolta J. Intravitreal autologous bone marrow CD34+ cell therapy for ischemic and degenerative retinal disorders: preliminary phase 1 clinical trial findings. Invest Ophthalmol Vis Sci. 2014 Dec 09; 56(1):81-9. PMID: 25491299.
      View in: PubMed
    21. Abou-El-Enein M, Bauer G, Reinke P. The business case for cell and gene therapies. Nat Biotechnol. 2014 Dec; 32(12):1192-3. PMID: 25489833.
      View in: PubMed
    22. Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE. Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2014 Nov 26; 6(264):264ra163. PMID: 25429056.
      View in: PubMed
    23. Abou-El-Enein M, Bauer G, Reinke P, Renner M, Schneider CK. A roadmap toward clinical translation of genetically-modified stem cells for treatment of HIV. Trends Mol Med. 2014 Nov; 20(11):632-42. PMID: 25262540.
      View in: PubMed
    24. Sheu J, Klassen H, Bauer G. Cellular manufacturing for clinical applications. Dev Ophthalmol. 2014; 53:178-88. PMID: 24732771.
      View in: PubMed
    25. Bauer G, Anderson JS. Stem cell transplantation in the context of HIV--how can we cure HIV infection? Expert Rev Clin Immunol. 2014 Jan; 10(1):107-16. PMID: 24308835.
      View in: PubMed
    26. Bauer G. HIV-1 vaccine antibody induction against a variable region of HIV-1: a possible link to protective immunity? Immunotherapy. 2013 May; 5(5):453-5. PMID: 23638741.
      View in: PubMed
    27. Abou-El-Enein M, Römhild A, Kaiser D, Beier C, Bauer G, Volk HD, Reinke P. Good Manufacturing Practices (GMP) manufacturing of advanced therapy medicinal products: a novel tailored model for optimizing performance and estimating costs. Cytotherapy. 2013 Mar; 15(3):362-83. PMID: 23579061.
      View in: PubMed
    28. Kalomoiris S, Lawson J, Chen RX, Bauer G, Nolta JA, Anderson JS. CD25 preselective anti-HIV vectors for improved HIV gene therapy. Hum Gene Ther Methods. 2012 Dec; 23(6):366-75. PMID: 23216020.
      View in: PubMed
    29. Annett G, Bauer G, Nolta JA. Mesenchymal stem cells for trinucleotide repeat disorders. Methods Mol Biol. 2013; 1010:79-91. PMID: 23754220.
      View in: PubMed
    30. Anderson JS, Bauer G. Fighting HIV with stem cell therapy: one step closer to human trials? Expert Rev Anti Infect Ther. 2012 Oct; 10(10):1071-3. PMID: 23199392.
      View in: PubMed
    31. Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood. 2012 Nov 01; 120(18):3635-46. PMID: 22968453.
      View in: PubMed
    32. Walker JE, Chen RX, McGee J, Nacey C, Pollard RB, Abedi M, Bauer G, Nolta JA, Anderson JS. Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector. J Virol. 2012 May; 86(10):5719-29. PMID: 22398281.
      View in: PubMed
    33. Adamo JE, Bauer G, Berro M, Burnett BK, Hartman KA, Masiello LM, Moorman-White D, Rubinstein EP, Schuff KG. A roadmap for academic health centers to establish good laboratory practice-compliant infrastructure. Acad Med. 2012 Mar; 87(3):279-84. PMID: 22373618.
      View in: PubMed
    34. Park SS, Caballero S, Bauer G, Shibata B, Roth A, Fitzgerald PG, Forward KI, Zhou P, McGee J, Telander DG, Grant MB, Nolta JA. Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2012 Feb; 53(2):986-94. PMID: 22247454.
      View in: PubMed
    35. Jung Y, Bauer G, Nolta JA. Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: progress toward safe clinical products. Stem Cells. 2012 Jan; 30(1):42-7. PMID: 21898694.
      View in: PubMed
    36. Olson SD, Pollock K, Kambal A, Cary W, Mitchell GM, Tempkin J, Stewart H, McGee J, Bauer G, Kim HS, Tempkin T, Wheelock V, Annett G, Dunbar G, Nolta JA. Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease. Mol Neurobiol. 2012 Feb; 45(1):87-98. PMID: 22161544.
      View in: PubMed
    37. Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol Ther. 2011 Mar; 19(3):584-93. PMID: 21119622.
      View in: PubMed
    38. Joyce N, Annett G, Wirthlin L, Olson S, Bauer G, Nolta JA. Mesenchymal stem cells for the treatment of neurodegenerative disease. Regen Med. 2010 Nov; 5(6):933-46. PMID: 21082892.
      View in: PubMed
    39. Meyerrose T, Olson S, Pontow S, Kalomoiris S, Jung Y, Annett G, Bauer G, Nolta JA. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev. 2010 Sep 30; 62(12):1167-74. PMID: 20920540.
      View in: PubMed
    40. Anderson JS, Walker J, Nolta JA, Bauer G. Specific transduction of HIV-susceptible cells for CCR5 knockdown and resistance to HIV infection: a novel method for targeted gene therapy and intracellular immunization. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):152-61. PMID: 19593160.
      View in: PubMed
    41. Anderson JS, Javien J, Nolta JA, Bauer G. Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 alpha protein, a CCR5 shRNA, and a TAR decoy. Mol Ther. 2009 Dec; 17(12):2103-14. PMID: 19690520.
      View in: PubMed
    42. Bauer G, Dao MA, Case SS, Meyerrose T, Wirthlin L, Zhou P, Wang X, Herrbrich P, Arevalo J, Csik S, Skelton DC, Walker J, Pepper K, Kohn DB, Nolta JA. In vivo biosafety model to assess the risk of adverse events from retroviral and lentiviral vectors. Mol Ther. 2008 Jul; 16(7):1308-15. PMID: 18461052.
      View in: PubMed
    43. Nervi B, Rettig MP, Ritchey JK, Wang HL, Bauer G, Walker J, Bonyhadi ML, Berenson RJ, Prior JL, Piwnica-Worms D, Nolta JA, DiPersio JF. Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice. Exp Hematol. 2007 Dec; 35(12):1823-38. PMID: 17764813.
      View in: PubMed
    44. Podsakoff GM, Engel BC, Carbonaro DA, Choi C, Smogorzewska EM, Bauer G, Selander D, Csik S, Wilson K, Betts MR, Koup RA, Nabel GJ, Bishop K, King S, Schmidt M, von Kalle C, Church JA, Kohn DB. Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells. Mol Ther. 2005 Jul; 12(1):77-86. PMID: 15963923.
      View in: PubMed
    45. Hofling AA, Sands MS, Lublin DM, Bauer G, Devine S. Collection of a mobilized peripheral blood apheresis product from a patient with mucopolysaccharidosis type VII and subsequent CD34+ cell isolation. J Clin Apher. 2004; 19(3):151-3. PMID: 15493049.
      View in: PubMed
    46. Li MJ, Bauer G, Michienzi A, Yee JK, Lee NS, Kim J, Li S, Castanotto D, Zaia J, Rossi JJ. Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs. Mol Ther. 2003 Aug; 8(2):196-206. PMID: 12907142.
      View in: PubMed
    47. Banerjea A, Li MJ, Bauer G, Remling L, Lee NS, Rossi J, Akkina R. Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Mol Ther. 2003 Jul; 8(1):62-71. PMID: 12842429.
      View in: PubMed
    48. Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol. 2002 May; 20(5):500-5. PMID: 11981565.
      View in: PubMed
    49. Moreau-Gaudry F, Xia P, Jiang G, Perelman NP, Bauer G, Ellis J, Surinya KH, Mavilio F, Shen CK, Malik P. High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors. Blood. 2001 Nov 01; 98(9):2664-72. PMID: 11675336.
      View in: PubMed
    50. Bauer G, Selander D, Engel B, Carbonaro D, Csik S, Rawlings S, Church J, Kohn DB. Gene therapy for pediatric AIDS. Ann N Y Acad Sci. 2000 Nov; 918:318-29. PMID: 11131719.
      View in: PubMed
    51. Engel BC, Bauer G, Pepper KA, Bockstoce DC, Yu XJ, Chen SY, Kohn DB. Intrakines--evidence for a trans-cellular mechanism of action. Mol Ther. 2000 Feb; 1(2):165-70. PMID: 10933927.
      View in: PubMed
    52. Kohn DB, Bauer G, Rice CR, Rothschild JC, Carbonaro DA, Valdez P, Hao Ql, Zhou C, Bahner I, Kearns K, Brody K, Fox S, Haden E, Wilson K, Salata C, Dolan C, Wetter C, Aguilar-Cordova E, Church J. A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children. Blood. 1999 Jul 01; 94(1):368-71. PMID: 10381536.
      View in: PubMed
    53. Case SS, Price MA, Jordan CT, Yu XJ, Wang L, Bauer G, Haas DL, Xu D, Stripecke R, Naldini L, Kohn DB, Crooks GM. Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2988-93. PMID: 10077624.
      View in: PubMed
    54. Davis BR, Saitta FP, Bauer G, Bunnell BA, Morgan RA, Schwartz DH. Targeted transduction of CD34+ cells by transdominant negative Rev-expressing retrovirus yields partial anti-HIV protection of progeny macrophages. Hum Gene Ther. 1998 May 20; 9(8):1197-207. PMID: 9625259.
      View in: PubMed
    55. Bauer G, Sauter S, Ibanez C, Rice CR, Valdez P, Jolly D, Kohn DB. Increased gene transfer into human CD34+ progenitor cells using retroviral vectors produced by a canine packaging cell line. Biol Blood Marrow Transplant. 1998; 4(3):119-27. PMID: 9923409.
      View in: PubMed
    56. Bauer G, Valdez P, Kearns K, Bahner I, Wen SF, Zaia JA, Kohn DB. Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34+ cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes. Blood. 1997 Apr 01; 89(7):2259-67. PMID: 9116267.
      View in: PubMed
    57. Kearns K, Bahner I, Bauer G, Wei SF, Valdez P, Wheeler S, Woods L, Miller R, Casciato D, Galpin J, Church J, Kohn DB. Suitability of bone marrow from HIV-1-infected donors for retrovirus-mediated gene transfer. Hum Gene Ther. 1997 Feb 10; 8(3):301-11. PMID: 9048197.
      View in: PubMed
    58. Chen P, Bauer G, Mitchell J, Factor R, Markham R, Schwartz DH. N-acetyl-cysteine and L-2-oxothiazolidine-4-carboxylic acid enhance contact-dependent growth of HIV in resting peripheral blood mononuclear cells (PBMC) in vitro and increase recovery of HIV from human-PBMC SCID mice. AIDS. 1997 Jan; 11(1):33-41. PMID: 9110073.
      View in: PubMed
    59. Farley JJ, Bauer G, Johnson JP, Cole GA. Phytohemagglutinin-inducible p24 in peripheral blood mononuclear cells as a predictor of human immunodeficiency virus type 1 vertical transmission and infant clinical status. Pediatr Infect Dis J. 1994 Dec; 13(12):1079-82. PMID: 7892074.
      View in: PubMed
    60. Bilello JA, Bauer G, Dudley MN, Cole GA, Drusano GL. Effect of 2',3'-didehydro-3'-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies. Antimicrob Agents Chemother. 1994 Jun; 38(6):1386-91. PMID: 8092842.
      View in: PubMed
    61. Kort JJ, Bilello JA, Bauer G, Drusano GL. Preclinical evaluation of antiviral activity and toxicity of Abbott A77003, an inhibitor of the human immunodeficiency virus type 1 protease. Antimicrob Agents Chemother. 1993 Jan; 37(1):115-9. PMID: 8431007.
      View in: PubMed
    62. Bauer G, Johnson J, Lewis G, Gottfried T, Urnovitz H, Cole G. Antibodies to HIV-1 in urine of children of HIV-1-infected women. Lancet. 1992 Aug 29; 340(8818):559. PMID: 1354317.
      View in: PubMed
    63. Cole GA, Bauer G, Kirsten E, Mendeleyev J, Bauer PI, Buki KG, Hakam A, Kun E. Inhibition of HIV-1 IIIb replication in AA-2 and MT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyrone. Biochem Biophys Res Commun. 1991 Oct 31; 180(2):504-14. PMID: 1953721.
      View in: PubMed