Pamela J Lein

Title(s)Professor, School of Veterinary Medicine
SchoolSchool of Veterinary Medicine
Address2009 Vet Med 3B
CA 95616
Phone530-752-1970
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    Collapse Research 
    Collapse Research Activities and Funding
    PCB Epigenomic Brain & Behavior Lasting Effects Study (PEBBLES)
    NIH/NIEHS R01ES029213Jun 1, 2018 - May 31, 2023
    Role: Co-Principal Investigator
    Vascular Inflammation and Exosomes as Mediators in Aging and Dementia
    NIH/NIA R01AG056710Mar 15, 2018 - Feb 28, 2023
    Role: Co-Principal Investigator
    Does air pollution increase risk of AD in a genetically susceptible animal model?
    NIH/NIEHS R21ES026515Jun 1, 2016 - May 31, 2018
    Role: Principal Investigator
    Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication
    NIH/NINDS U54NS079202Sep 1, 2012 - May 31, 2022
    Role: Principal Investigator
    Identification of novel therapeutic approaches for TETS and OP intoxication
    NIH/NINDS R21NS072094Sep 30, 2010 - Aug 31, 2013
    Role: Principal Investigator
    Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity
    NIH/NIEHS R01ES017592Jul 7, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Enantioselective Metabolism Influences PCB Developmental Neurotoxicity
    NIH/NIEHS R01ES017425Jan 26, 2010 - Dec 31, 2015
    Role: Co-Principal Investigator
    Biomarkers of Organophosphorus Pesticide-Induced Neurotoxicity
    NIH/NIEHS R01ES016308Jun 1, 2008 - Apr 30, 2013
    Role: Co-Principal Investigator
    Molecular and Cellular Basis of PCB Developmental Neurotoxicity
    NIH/NIEHS R56ES014901Aug 1, 2007 - Jul 31, 2008
    Role: Principal Investigator
    Molecular and Cellular Basis of PCB Developmental Neurotoxicity
    NIH/NIEHS R01ES014901Jul 1, 2006 - Nov 30, 2019
    Role: Principal Investigator
    Molecular Regulation of Primary Dendritogenesis
    NIH/NINDS R21NS045037Jan 15, 2004 - Dec 31, 2006
    Role: Principal Investigator
    Retrograde Dystrophic Influence of IFN-gamma on Neurons
    NIH/NINDS R01NS046649Jul 16, 2003 - Apr 30, 2009
    Role: Principal Investigator
    Mechanism of organophosphate development neurotoxicity
    NIH/NIEHS R21ES011771Mar 15, 2002 - Jul 31, 2005
    Role: Principal Investigator
    Do PCBs alter developing brain structure and cognition?
    NIH/NICHD R03HD040936Mar 15, 2002 - Aug 31, 2004
    Role: Principal Investigator
    REGULATION OF DENDRITIC GROWTH BY OSTEOGENIC PROTEIN-1
    NIH/NINDS R15NS036401May 15, 1997 - Apr 30, 2000
    Role: Principal Investigator
    CELL BIOLOGY OF HUMAN TILS ENGRAFTED INTO SCID MICE
    NIH/NCI F32CA009177Feb 19, 1992
    Role: Principal Investigator
    Advanced Training in Environmental Health Sciences
    NIH/NIEHS T32ES007059Jul 1, 1978 - Jun 30, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures. Neuropharmacology. 2024 Mar 23; 109918. Hobson BA, Rowland DR, Dou Y, Saito N, Harmany ZT, Bruun DA, Harvey DJ, Chaudhari A, Garbow JR, Lein PJ. PMID: 38527652.
      View in: PubMed   Mentions:    Fields:    
    2. Rat primary cortical cell tri-culture to study effects of amyloid-beta on microglia function. bioRxiv. 2024 Mar 17. Kim H, Le B, Goshi N, Zhu K, Grodzki AC, Lein PJ, Zhao M, Seker E. PMID: 38558989; PMCID: PMC10979983.
      View in: PubMed   Mentions:
    3. Quantitative T2 mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication. Neuropharmacology. 2024 Mar 02; 249:109895. Almeida AJD, Hobson BA, Saito N, Bruun DA, Porter VA, Harvey DJ, Garbow JR, Chaudhari AJ, Lein PJ. PMID: 38437913.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Dietary resistant starch supplementation increases gut luminal deoxycholic acid abundance in mice. Gut Microbes. 2024 Jan-Dec; 16(1):2315632. Reuter MA, Tucker M, Marfori Z, Shishani R, Bustamante JM, Moreno R, Goodson ML, Ehrlich A, Taha AY, Lein PJ, Joshi N, Brito I, Durbin-Johnson B, Nandakumar R, Cummings BP. PMID: 38375831; PMCID: PMC10880513.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Fully automated whole brain segmentation from rat MRI scans with a convolutional neural network. J Neurosci Methods. 2024 Feb 08; 110078. Porter VA, Hobson BA, Foster B, Lein PJ, Chaudhari AJ. PMID: 38340902.
      View in: PubMed   Mentions:    Fields:    
    6. Cardiovascular responses of adult male Sprague-Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone. Arch Toxicol. 2024 Apr; 98(4):1177-1189. Pan S, Bruun DA, Lein PJ, Chen CY. PMID: 38305864; PMCID: PMC10944447.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Evidence Implicating Blood-Brain Barrier Impairment in the Pathogenesis of Acquired Epilepsy following Acute Organophosphate Intoxication. J Pharmacol Exp Ther. 2024 Jan 17; 388(2):301-312. Bernardino PN, Luo AS, Andrew PM, Unkel CM, Gonzalez MI, Gelli A, Lein PJ. PMID: 37827702; PMCID: PMC10801776.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    8. Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4+ T cells. Front Immunol. 2023; 14:1193535. Sandoval S, Malany K, Thongphanh K, Martinez CA, Goodson ML, Souza FDC, Lin LW, Sweeney N, Pennington J, Lein PJ, Kerkvliet NI, Ehrlich AK. PMID: 38035105; PMCID: PMC10682649.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    9. Time- and region-dependent blood-brain barrier impairment in a rat model of organophosphate-induced status epilepticus. Neurobiol Dis. 2023 Oct 15; 187:106316. Bernardino PN, Hobson BA, Huddleston SL, Andrew PM, MacMahon JA, Saito NH, Porter VA, Bruun DA, Harvey DJ, Garbow JR, Gelli A, Chaudhari AJ, Lein PJ. PMID: 37797902; PMCID: PMC11000668.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    10. Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2 responding CD4 + T cells. bioRxiv. 2023 Sep 28. Sandoval S, Malany K, Thongphanh K, Martinez CA, Goodson ML, Souza FDC, Lin LW, Pennington J, Lein PJ, Kerkvliet NI, Ehrlich AK. PMID: 37808764; PMCID: PMC10557576.
      View in: PubMed   Mentions:
    11. Editorial: Advances in understanding the pathogenetic mechanisms of neurodevelopmental disorders and neurodegenerative disease - The environment as a putative risk factor. Front Neurol. 2023; 14:1259772. Lavezzi AM, Colizzi M, Lein PJ. PMID: 37602235; PMCID: PMC10435968.
      View in: PubMed   Mentions:
    12. Assessing CaMPARI as new approach methodology for evaluating neurotoxicity. Neurotoxicology. 2023 Jul; 97:109-119. Biechele-Speziale D, Camarillo M, Martin NR, Biechele-Speziale J, Lein PJ, Plavicki JS. PMID: 37244562; PMCID: PMC10527633.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs. Epilepsia Open. 2023 06; 8(2):666-672. Bruun DA, Ma B, Chen YJ, Wu CY, Aleman M, Zolkowska D, Smiley-Jewell SM, Rogawski MA, Lein PJ. PMID: 36919379; PMCID: PMC10235566.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    14. Gamma secretase activity modulates BMP-7-induced dendritic growth in primary rat sympathetic neurons. Auton Neurosci. 2023 07; 247:103085. Karunungan K, Garza RH, Grodzki AC, Holt M, Lein PJ, Chandrasekaran V. PMID: 37031474; PMCID: PMC10330319.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Rebuttal to Correspondence on "Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples". Environ Sci Technol. 2023 04 18; 57(15):6251-6252. Zhang CY, Li X, Keil Stietz KP, Sethi S, Yang W, Marek RF, Ding X, Lein PJ, Hornbuckle KC, Lehmler HJ. PMID: 37017328; PMCID: PMC10518181.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2. Arch Toxicol. 2023 05; 97(5):1355-1365. Mundy PC, Werner A, Singh L, Singh V, Mendieta R, Patullo CE, Wulff H, Lein PJ. PMID: 36912926; PMCID: PMC10110628.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Oxidized linoleic acid metabolites regulate neuronal morphogenesis in vitro. Neurochem Int. 2023 03; 164:105506. da Costa Souza F, Grodzki ACG, Morgan RK, Zhang Z, Taha AY, Lein PJ. PMID: 36758902; PMCID: PMC10495953.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish (Danio rerio). ACS Chem Neurosci. 2023 03 01; 14(5):875-884. Tombari RJ, Mundy PC, Morales KM, Dunlap LE, Olson DE, Lein PJ. PMID: 36753397; PMCID: PMC9983010.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    19. Novel image analysis tool for rapid screening of cell morphology in preclinical animal models of disease. Heliyon. 2023 Feb; 9(2):e13449. Guignet M, Schmuck M, Harvey DJ, Nguyen D, Bruun D, Echeverri A, Gurkoff G, Lein PJ. PMID: 36873154; PMCID: PMC9975095.
      View in: PubMed   Mentions: 1  
    20. Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment. Environ Res. 2023 03 01; 220:115227. Mouat JS, Li X, Neier K, Zhu Y, Mordaunt CE, La Merrill MA, Lehmler HJ, Jones MP, Lein PJ, Schmidt RJ, LaSalle JM. PMID: 36608759; PMCID: PMC10518186.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. A systematic evidence map for the evaluation of noncancer health effects and exposures to polychlorinated biphenyl mixtures. Environ Res. 2023 03 01; 220:115148. Carlson LM, Christensen K, Sagiv SK, Rajan P, Klocke CR, Lein PJ, Coffman E, Shaffer RM, Yost EE, Arzuaga X, Factor-Litvak P, Sergeev A, Toborek M, Bloom MS, Trgovcich J, Jusko TA, Robertson L, Meeker JD, Keating AF, Blain R, Silva RA, Snow S, Lin C, Shipkowski K, Ingle B, Lehmann GM. PMID: 36580985; PMCID: PMC10013199.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    22. Gene×environment interactions in autism spectrum disorders. Curr Top Dev Biol. 2023; 152:221-284. Keil-Stietz K, Lein PJ. PMID: 36707213; PMCID: PMC10496028.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Probing changes in brain esterified oxylipin concentrations during the early stages of pathogenesis in Alzheimer's Disease transgenic rats. Neurosci Lett. 2022 11 20; 791:136921. Shen Q, Patten KT, Valenzuela A, Lein PJ, Taha AY. PMID: 36270451.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    24. Influence of microchannel geometry on device performance and electrophysiological recording fidelity during long-term studies of connected neural populations. Lab Chip. 2022 10 11; 22(20):3961-3975. Goshi N, Girardi G, da Costa Souza F, Gardner A, Lein PJ, Seker E. PMID: 36111641; PMCID: PMC9639432.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    25. Ryanodine receptor-active non-dioxin-like polychlorinated biphenyls cause neurobehavioral deficits in larval zebrafish. Front Toxicol. 2022; 4:947795. Yaghoobi B, Miller GW, Holland EB, Li X, Harvey D, Li S, Lehmler HJ, Pessah IN, Lein PJ. PMID: 36278027; PMCID: PMC9582434.
      View in: PubMed   Mentions: 5  
    26. Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples. Environ Sci Technol. 2022 09 20; 56(18):13169-13178. Zhang CY, Li X, Keil Stietz KP, Sethi S, Yang W, Marek RF, Ding X, Lein PJ, Hornbuckle KC, Lehmler HJ. PMID: 36047920; PMCID: PMC9573770.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    27. Providing height to pullets does not influence hippocampal dendritic morphology or brain-derived neurotrophic factor at the end of the rearing period. Poult Sci. 2022 Dec; 101(12):102161. Pullin AN, Farrar VS, Loxterkamp JW, Jones CT, Calisi RM, Horback K, Lein PJ, Makagon MM. PMID: 36252500; PMCID: PMC9579382.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats. Environ Toxicol Pharmacol. 2022 Jul; 93:103875. Liang N, Emami S, Patten KT, Valenzuela AE, Wallis CD, Wexler AS, Bein KJ, Lein PJ, Taha AY. PMID: 35550873; PMCID: PMC9353974.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    29. Diisopropylfluorophosphate (DFP) volatizes and cross-contaminates wells in a common 96-well plate format used in zebrafish larvae toxicology studies. J Pharmacol Toxicol Methods. 2022 May-Jun; 115:107173. Mundy PC, Mendieta R, Lein PJ. PMID: 35545188; PMCID: PMC9356770.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    30. Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions. Prog Lipid Res. 2022 04; 86:101165. Dyall SC, Balas L, Bazan NG, Brenna JT, Chiang N, da Costa Souza F, Dalli J, Durand T, Galano JM, Lein PJ, Serhan CN, Taha AY. PMID: 35508275; PMCID: PMC9346631.
      View in: PubMed   Mentions: 82     Fields:    
    31. Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner. Front Cell Neurosci. 2022; 16:861733. Patten KT, Valenzuela AE, Wallis C, Harvey DJ, Bein KJ, Wexler AS, Gorin FA, Lein PJ. PMID: 35530180; PMCID: PMC9072828.
      View in: PubMed   Mentions: 2  
    32. Implementation of Zebrafish Ontologies for Toxicology Screening. Front Toxicol. 2022; 4:817999. Thessen AE, Marvel S, Achenbach JC, Fischer S, Haendel MA, Hayward K, Klüver N, Könemann S, Legradi J, Lein P, Leong C, Mylroie JE, Padilla S, Perone D, Planchart A, Prieto RM, Muriana A, Quevedo C, Reif D, Ryan K, Stinckens E, Truong L, Vergauwen L, Vom Berg C, Wilbanks M, Yaghoobi B, Hamm J. PMID: 35387429; PMCID: PMC8979167.
      View in: PubMed   Mentions: 3  
    33. Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer's disease. Toxicol Rep. 2022; 9:432-444. Dutta M, Weigel KM, Patten KT, Valenzuela AE, Wallis C, Bein KJ, Wexler AS, Lein PJ, Cui JY. PMID: 35310146; PMCID: PMC8927974.
      View in: PubMed   Mentions: 4  
    34. Emulating Near-Roadway Exposure to Traffic-Related Air Pollution via Real-Time Emissions from a Major Freeway Tunnel System. Environ Sci Technol. 2022 Mar 02. Bein KJ, Wallis CD, Silverman JL, Lein PJ, Wexler AS. PMID: 35235290; PMCID: PMC9437142.
      View in: PubMed   Mentions: 2     Fields:    
    35. Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure. Cell Rep. 2022 03 01; 38(9):110442. Laufer BI, Neier K, Valenzuela AE, Yasui DH, Schmidt RJ, Lein PJ, LaSalle JM. PMID: 35235788; PMCID: PMC8941983.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    36. Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures. Toxics. 2022 Feb 18; 10(2). Chen H, Carty RK, Bautista AC, Hayakawa KA, Lein PJ. PMID: 35202279; PMCID: PMC8879960.
      View in: PubMed   Mentions:
    37. Correction to: A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. J Neuroinflammation. 2022 Feb 12; 19(1):49. Goshi N, Morgan RK, Lein PJ, Seker E. PMID: 35151333; PMCID: PMC8840776.
      View in: PubMed   Mentions: 3     Fields:    
    38. Review of evidence implicating the plasminogen activator system in blood-brain barrier dysfunction associated with Alzheimer's disease. Ageing Neurodegener Dis. 2022; 2. Tang MY, Gorin FA, Lein PJ. PMID: 35156107; PMCID: PMC8830591.
      View in: PubMed   Mentions: 4  
    39. Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium. Front Neurosci. 2021; 15:766826. Sethi S, Keil Stietz KP, Valenzuela AE, Klocke CR, Silverman JL, Puschner B, Pessah IN, Lein PJ. PMID: 34938155; PMCID: PMC8685320.
      View in: PubMed   Mentions: 13  
    40. Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polychlorinated Biphenyls Mixture in the Juvenile Mouse. Front Neurosci. 2021; 15:766802. Keil Stietz KP, Sethi S, Klocke CR, de Ruyter TE, Wilson MD, Pessah IN, Lein PJ. PMID: 34924936; PMCID: PMC8678536.
      View in: PubMed   Mentions: 8  
    41. Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats. Curr Res Toxicol. 2021; 2:341-356. González EA, Calsbeek JJ, Tsai YH, Tang MY, Andrew P, Vu J, Berg EL, Saito NH, Harvey DJ, Supasai S, Gurkoff GG, Silverman JL, Lein PJ. PMID: 34622217; PMCID: PMC8484742.
      View in: PubMed   Mentions: 6  
    42. Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate. Neurotoxicology. 2021 12; 87:106-119. Calsbeek JJ, González EA, Bruun DA, Guignet MA, Copping N, Dawson ME, Yu AJ, MacMahon JA, Saito NH, Harvey DJ, Silverman JL, Lein PJ. PMID: 34509511; PMCID: PMC8595753.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    43. Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus. Neurotoxicology. 2021 12; 87:43-50. Calsbeek JJ, González EA, Boosalis CA, Zolkowska D, Bruun DA, Rowland DJ, Saito NH, Harvey DJ, Chaudhari AJ, Rogawski MA, Garbow JR, Lein PJ. PMID: 34478772; PMCID: PMC8595842.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    44. The efficacy of γ-aminobutyric acid type A receptor (GABA AR) subtype-selective positive allosteric modulators in blocking tetramethylenedisulfotetramine (TETS)-induced seizure-like behavior in larval zebrafish with minimal sedation. Toxicol Appl Pharmacol. 2021 09 01; 426:115643. Mundy PC, Pressly B, Carty DR, Yaghoobi B, Wulff H, Lein PJ. PMID: 34265354; PMCID: PMC8514104.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    45. Neuroinflammation as a Therapeutic Target for Mitigating the Long-Term Consequences of Acute Organophosphate Intoxication. Front Pharmacol. 2021; 12:674325. Andrew PM, Lein PJ. PMID: 34054549; PMCID: PMC8153682.
      View in: PubMed   Mentions: 6  
    46. The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer's Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats. Environ Health Perspect. 2021 05; 129(5):57005. Patten KT, Valenzuela AE, Wallis C, Berg EL, Silverman JL, Bein KJ, Wexler AS, Lein PJ. PMID: 33971107; PMCID: PMC8110309.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsPHPublic Health
    47. Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab062. Toedebusch R, Grodzki AC, Dickinson PJ, Woolard K, Vinson N, Sturges B, Snyder J, Li CF, Nagasaka O, Consales B, Vernau K, Knipe M, Murthy V, Lein PJ, Toedebusch CM. PMID: 34131649; PMCID: PMC8193901.
      View in: PubMed   Mentions: 8  
    48. Mechanisms of organophosphate neurotoxicity. Curr Opin Toxicol. 2021 Jun; 26:49-60. Tsai YH, Lein PJ. PMID: 34308007; PMCID: PMC8302047.
      View in: PubMed   Mentions: 11  
    49. Developmental exposure to DDT or DDE alters sympathetic innervation of brown adipose in adult female mice. Environ Health. 2021 04 01; 20(1):37. vonderEmbse AN, Elmore SE, Jackson KB, Habecker BA, Manz KE, Pennell KD, Lein PJ, La Merrill MA. PMID: 33794904; PMCID: PMC8017793.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    50. Disposition of PCB 11 in Mice Following Acute Oral Exposure. Chem Res Toxicol. 2021 04 19; 34(4):988-991. Zhang CY, Klocke CR, Lein PJ, Lehmler HJ. PMID: 33734669; PMCID: PMC8058299.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    51. Investigation of NH3 as a selective thyroid hormone receptor modulator in larval zebrafish (Danio rerio). Neurotoxicology. 2021 05; 84:96-104. Walter KM, Singh L, Singh V, Lein PJ. PMID: 33745965; PMCID: PMC8119357.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    52. Co-localization of fluorescent signals using deep learning with Manders overlapping coefficient. Proc SPIE Int Soc Opt Eng. 2021 Feb; 11596. Dou Y, Tsai YH, Liu CC, Hobson BA, Lein PJ. PMID: 34305257; PMCID: PMC8301216.
      View in: PubMed   Mentions:
    53. In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder. Curr Res Toxicol. 2021; 2:1-18. Keil Stietz KP, Kennedy CL, Sethi S, Valenzuela A, Nunez A, Wang K, Wang Z, Wang P, Spiegelhoff A, Puschner B, Bjorling DE, Lein PJ. PMID: 34337439; PMCID: PMC8317607.
      View in: PubMed   Mentions: 7  
    54. Iron Deficiency and Iron Excess Differently Affect Dendritic Architecture of Pyramidal Neurons in the Hippocampus of Piglets. J Nutr. 2021 01 04; 151(1):235-244. Perng V, Li C, Klocke CR, Navazesh SE, Pinneles DK, Lein PJ, Ji P. PMID: 33245133.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    55. Linoleic acid-derived 13-hydroxyoctadecadienoic acid is absorbed and incorporated into rat tissues. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 03; 1866(3):158870. Zhang Z, Emami S, Hennebelle M, Morgan RK, Lerno LA, Slupsky CM, Lein PJ, Taha AY. PMID: 33340768; PMCID: PMC7979545.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    56. Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos. J Neurodev Disord. 2020 12 16; 12(1):40. Berg EL, Ching TM, Bruun DA, Rivera JK, Careaga M, Ellegood J, Lerch JP, Wöhr M, Lein PJ, Silverman JL. PMID: 33327943; PMCID: PMC7745485.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    57. A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature. 2021 01; 589(7842):474-479. Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE. PMID: 33299186; PMCID: PMC7874389.
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    58. Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution. Environ Health Perspect. 2020 12; 128(12):127003. Edwards S, Zhao G, Tran J, Patten KT, Valenzuela A, Wallis C, Bein KJ, Wexler AS, Lein PJ, Rao X. PMID: 33275451; PMCID: PMC7717845.
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    59. Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform. Front Cell Dev Biol. 2020; 8:586296. Colón-Rodríguez A, Uribe-Salazar JM, Weyenberg KB, Sriram A, Quezada A, Kaya G, Jao E, Radke B, Lein PJ, Dennis MY. PMID: 33330465; PMCID: PMC7719691.
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    60. Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? Toxics. 2020 Sep 17; 8(3). Panesar HK, Kennedy CL, Keil Stietz KP, Lein PJ. PMID: 32957475; PMCID: PMC7560399.
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    61. Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Ann N Y Acad Sci. 2020 11; 1480(1):183-206. Dhir A, Bruun DA, Guignet M, Tsai YH, González E, Calsbeek J, Vu J, Saito N, Tancredi DJ, Harvey DJ, Lein PJ, Rogawski MA. PMID: 32915470; PMCID: PMC7756871.
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    62. Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth. ACS Pharmacol Transl Sci. 2021 Apr 09; 4(2):452-460. Ly C, Greb AC, Vargas MV, Duim WC, Grodzki ACG, Lein PJ, Olson DE. PMID: 33860174; PMCID: PMC8033616.
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    63. Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate. Eur J Pharmacol. 2020 Nov 05; 886:173538. Supasai S, González EA, Rowland DJ, Hobson B, Bruun DA, Guignet MA, Soares S, Singh V, Wulff H, Saito N, Harvey DJ, Lein PJ. PMID: 32898549; PMCID: PMC7572820.
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    64. Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats. Transl Psychiatry. 2020 08 17; 10(1):289. Berg EL, Pedersen LR, Pride MC, Petkova SP, Patten KT, Valenzuela AE, Wallis C, Bein KJ, Wexler A, Lein PJ, Silverman JL. PMID: 32807767; PMCID: PMC7431542.
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    65. A national toxicology program systematic review of the evidence for long-term effects after acute exposure to sarin nerve agent. Crit Rev Toxicol. 2020 07; 50(6):474-490. Jett DA, Sibrizzi CA, Blain RB, Hartman PA, Lein PJ, Taylor KW, Rooney AA. PMID: 32755358; PMCID: PMC8011809.
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    66. The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls. Curr Res Toxicol. 2020 Jun 10; 1:85-103. Matelski L, Keil Stietz KP, Sethi S, Taylor SL, Van de Water J, Lein PJ. PMID: 34296199; PMCID: PMC8294704.
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    67. Translational Toxicology in Zebrafish. Curr Opin Toxicol. 2020 Oct-Dec; 23-24:56-66. Tal T, Yaghoobi B, Lein PJ. PMID: 32656393; PMCID: PMC7351119.
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    68. Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats. Transl Psychiatry. 2020 05 27; 10(1):166. Patten KT, González EA, Valenzuela A, Berg E, Wallis C, Garbow JR, Silverman JL, Bein KJ, Wexler AS, Lein PJ. PMID: 32483143; PMCID: PMC7264203.
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    69. Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat cortical neurons in culture. J Neurosci Methods. 2020 07 15; 341:108793. Schmuck MR, Keil KP, Sethi S, Morgan RK, Lein PJ. PMID: 32461071; PMCID: PMC7357201.
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    70. Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation. Sci Rep. 2020 05 18; 10(1):8204. Petkova SP, Pride M, Klocke C, Fenton TA, White J, Lein PJ, Ellegood J, Lerch JP, Silverman JL, Waldau B. PMID: 32424171; PMCID: PMC7235216.
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    71. A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. J Neuroinflammation. 2020 May 11; 17(1):155. Goshi N, Morgan RK, Lein PJ, Seker E. PMID: 32393376; PMCID: PMC7216677.
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    72. Preface to the NeuroToxicology Special Issue, "Mercury in fish: The Seychelles child development study". Neurotoxicology. 2020 07; 79:211. Myers G, van Wijngaarden E, Lasley SM, Cranmer JM, Lein PJ, Westerink RHS. PMID: 32437763.
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    73. The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Arch Toxicol. 2020 06; 94(6):2149-2162. González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. PMID: 32303805; PMCID: PMC7305973.
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    74. Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice. Arch Toxicol. 2020 06; 94(6):1995-2007. Pressly B, Vasylieva N, Barnych B, Singh V, Singh L, Bruun DA, Hwang SH, Chen YJ, Fettinger JC, Johnnides S, Lein PJ, Yang J, Hammock BD, Wulff H. PMID: 32239239; PMCID: PMC7303059.
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    75. Evidence Implicating Non-Dioxin-Like Congeners as the Key Mediators of Polychlorinated Biphenyl (PCB) Developmental Neurotoxicity. Int J Mol Sci. 2020 Feb 04; 21(3). Klocke C, Lein PJ. PMID: 32033061; PMCID: PMC7037228.
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    76. Magnitude of behavioral deficits varies with job-related chlorpyrifos exposure levels among Egyptian pesticide workers. Neurotoxicology. 2020 03; 77:216-230. Anger WK, Farahat FM, Lein PJ, Lasarev MR, Olson JR, Farahat TM, Rohlman DS. PMID: 32006538; PMCID: PMC7085493.
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    77. Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies. J Med Chem. 2020 02 13; 63(3):1142-1155. Dunlap LE, Azinfar A, Ly C, Cameron LP, Viswanathan J, Tombari RJ, Myers-Turnbull D, Taylor JC, Grodzki AC, Lein PJ, Kokel D, Olson DE. PMID: 31977208; PMCID: PMC7075704.
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    78. Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line. Mol Psychiatry. 2021 03; 26(3):875-887. Matelski L, Morgan RK, Grodzki AC, Van de Water J, Lein PJ. PMID: 31965031; PMCID: PMC7371517.
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    79. Editorial: influence of the microbiome on neurotoxic outcomes. Neurotoxicology. 2020 03; 77:29. Doorn J, Lein P. PMID: 31811870.
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    80. Susceptibility of larval zebrafish to the seizurogenic activity of GABA type A receptor antagonists. Neurotoxicology. 2020 01; 76:220-234. Bandara SB, Carty DR, Singh V, Harvey DJ, Vasylieva N, Pressly B, Wulff H, Lein PJ. PMID: 31811871; PMCID: PMC6957304.
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    81. Gene-environment interactions determine risk for dementia: the influence of lifestyle on genetic risk for dementia. Ann Transl Med. 2019 Dec; 7(Suppl 8):S322. Patten KT, Lein PJ. PMID: 32016040; PMCID: PMC6976405.
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    82. Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner. J Neurochem. 2020 01; 152(2):195-207. Hennebelle M, Morgan RK, Sethi S, Zhang Z, Chen H, Grodzki AC, Lein PJ, Taha AY. PMID: 31283837; PMCID: PMC6949423.
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    83. The developmental neurotoxicity of legacy vs. contemporary polychlorinated biphenyls (PCBs): similarities and differences. Environ Sci Pollut Res Int. 2020 Mar; 27(9):8885-8896. Klocke C, Sethi S, Lein PJ. PMID: 31713823; PMCID: PMC7220795.
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    84. Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells. Am J Respir Cell Mol Biol. 2019 11; 61(5):620-630. Proskocil BJ, Grodzki ACG, Jacoby DB, Lein PJ, Fryer AD. PMID: 30978295; PMCID: PMC6827067.
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    85. Acute peripheral immune activation alters cytokine expression and glial activation in the early postnatal rat brain. J Neuroinflammation. 2019 Oct 31; 16(1):200. Bruce M, Streifel KM, Boosalis CA, Heuer L, González EA, Li S, Harvey DJ, Lein PJ, Van de Water J. PMID: 31672161; PMCID: PMC6822372.
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    86. Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison. PLoS One. 2019; 14(9):e0221230. Walter KM, Dach K, Hayakawa K, Giersiefer S, Heuer H, Lein PJ, Fritsche E. PMID: 31513589; PMCID: PMC6742404.
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    87. Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicol Appl Pharmacol. 2019 11 01; 382:114749. Yang J, Bruun DA, Wang C, Wan D, McReynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. PMID: 31521729; PMCID: PMC6957308.
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    88. TSPO PET Using [18F]PBR111 Reveals Persistent Neuroinflammation Following Acute Diisopropylfluorophosphate Intoxication in the Rat. Toxicol Sci. 2019 08 01; 170(2):330-344. Hobson BA, Rowland DJ, Sisó S, Guignet MA, Harmany ZT, Bandara SB, Saito N, Harvey DJ, Bruun DA, Garbow JR, Chaudhari AJ, Lein PJ. PMID: 31087103; PMCID: PMC6657665.
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    89. Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice. Environ Pollut. 2019 Oct; 253:708-721. Rude KM, Pusceddu MM, Keogh CE, Sladek JA, Rabasa G, Miller EN, Sethi S, Keil KP, Pessah IN, Lein PJ, Gareau MG. PMID: 31336350; PMCID: PMC6719698.
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    90. The Use of Percent Change in RR Interval for Data Exclusion in Analyzing 24-h Time Domain Heart Rate Variability in Rodents. Front Physiol. 2019; 10:693. Karey E, Pan S, Morris AN, Bruun DA, Lein PJ, Chen CY. PMID: 31244671; PMCID: PMC6562196.
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    91. Changes in thyroid hormone activity disrupt photomotor behavior of larval zebrafish. Neurotoxicology. 2019 09; 74:47-57. Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ. PMID: 31121238; PMCID: PMC6750994.
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    92. MicroRNAs are Necessary for BMP-7-induced Dendritic Growth in Cultured Rat Sympathetic Neurons. Cell Mol Neurobiol. 2019 Oct; 39(7):917-934. Pravoverov K, Whiting K, Thapa S, Bushong T, Trang K, Lein PJ, Chandrasekaran V. PMID: 31104181; PMCID: PMC6713596.
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    93. Neurotoxicity of polychlorinated biphenyls and related organohalogens. Acta Neuropathol. 2019 09; 138(3):363-387. Pessah IN, Lein PJ, Seegal RF, Sagiv SK. PMID: 30976975; PMCID: PMC6708608.
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    94. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. Neurobiol Dis. 2020 01; 133:104431. Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. PMID: 30905768; PMCID: PMC6754818.
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    95. Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Activity at the Thyroid Hormone Receptor and Ryanodine Receptor. Environ Sci Technol. 2019 04 02; 53(7):3948-3958. Sethi S, Morgan RK, Feng W, Lin Y, Li X, Luna C, Koch M, Bansal R, Duffel MW, Puschner B, Zoeller RT, Lehmler HJ, Pessah IN, Lein PJ. PMID: 30821444; PMCID: PMC6457253.
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    96. Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication. Neurotoxicology. 2019 07; 73:81-84. Bruun DA, Guignet M, Harvey DJ, Lein PJ. PMID: 30853371; PMCID: PMC6634995.
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    97. Sex-Dependent Effects of 2,2',3,5',6-Pentachlorobiphenyl on Dendritic Arborization of Primary Mouse Neurons. Toxicol Sci. 2019 03 01; 168(1):95-109. Keil KP, Sethi S, Lein PJ. PMID: 30395321; PMCID: PMC6390665.
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    98. Commentary: Fc Gamma Receptors are Expressed in the Developing Rat Brain and Activate Downstream Signaling Molecules upon Cross-Linking with Immune Complex. J Neurol Neuromedicine. 2019; 4(1):26-29. Stamou M, Lein PJ. PMID: 31131371; PMCID: PMC6532780.
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    99. Teratological and Behavioral Screening of the National Toxicology Program 91-Compound Library in Zebrafish (Danio rerio). Toxicol Sci. 2019 01 01; 167(1):77-91. Dach K, Yaghoobi B, Schmuck MR, Carty DR, Morales KM, Lein PJ. PMID: 30364989; PMCID: PMC6317431.
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    100. Effects of thyroid hormone disruption on the ontogenetic expression of thyroid hormone signaling genes in developing zebrafish (Danio rerio). Gen Comp Endocrinol. 2019 02 01; 272:20-32. Walter KM, Miller GW, Chen X, Yaghoobi B, Puschner B, Lein PJ. PMID: 30448381; PMCID: PMC6331280.
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    101. Developmental exposure to silver nanoparticles at environmentally relevant concentrations alters swimming behavior in zebrafish (Danio rerio). Environ Toxicol Chem. 2018 12; 37(12):3018-3024. González EA, Carty DR, Tran FD, Cole AM, Lein PJ. PMID: 30242895; PMCID: PMC6457247.
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    102. Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. Genes Brain Behav. 2019 01; 18(1):e12526. Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. PMID: 30311737; PMCID: PMC6540090.
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    103. Increased severity of fragile X spectrum disorders in the agricultural community of Ricaurte, Colombia. Int J Dev Neurosci. 2019 Feb; 72:1-5. Saldarriaga W, Salcedo-Arellano MJ, Rodriguez-Guerrero T, Ríos M, Fandiño-Losada A, Ramirez-Cheyne J, Lein PJ, Tassone F, Hagerman RJ. PMID: 30385191; PMCID: PMC6354926.
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    104. Developmental exposure to environmentally relevant concentrations of bifenthrin alters transcription of mTOR and ryanodine receptor-dependent signaling molecules and impairs predator avoidance behavior across early life stages in inland silversides (Menidia beryllina). Aquat Toxicol. 2019 Jan; 206:1-13. Frank DF, Brander SM, Hasenbein S, Harvey DJ, Lein PJ, Geist J, Connon RE. PMID: 30414561; PMCID: PMC6464817.
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    105. 3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism. Arch Toxicol. 2018 11; 92(11):3337-3345. Sethi S, Keil KP, Lein PJ. PMID: 30225637; PMCID: PMC6196112.
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    106. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats. Toxicol Sci. 2018 09 01; 165(1):244-253. Shaffo FC, Grodzki AC, Schelegle ES, Lein PJ. PMID: 29939342; PMCID: PMC6135637.
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    107. PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Arch Toxicol. 2018 10; 92(10):3163-3173. Keil KP, Miller GW, Chen H, Sethi S, Schmuck MR, Dhakal K, Kim JW, Lein PJ. PMID: 30132043; PMCID: PMC6162988.
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    108. Mechanisms of organophosphorus pesticide toxicity in the context of airway hyperreactivity and asthma. Am J Physiol Lung Cell Mol Physiol. 2018 10 01; 315(4):L485-L501. Shaffo FC, Grodzki AC, Fryer AD, Lein PJ. PMID: 29952220; PMCID: PMC6230874.
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    109. A Microfluidic Platform to Study Astrocyte Adhesion on Nanoporous Gold Thin Films. Nanomaterials (Basel). 2018 Jun 21; 8(7). Hampe AE, Li Z, Sethi S, Lein PJ, Seker E. PMID: 29933551; PMCID: PMC6070884.
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    110. Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity. Neurotoxicology. 2018 07; 67:102-111. Miller GW, Chandrasekaran V, Yaghoobi B, Lein PJ. PMID: 29704525; PMCID: PMC6177215.
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    111. Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). Aquat Toxicol. 2018 Jul; 200:50-61. Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ. PMID: 29727771; PMCID: PMC5992106.
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    112. Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes. Toxicol Appl Pharmacol. 2018 09 01; 354:3-6. Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A. PMID: 29447839; PMCID: PMC6097873.
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    113. Developmental social communication deficits in the Shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder. Autism Res. 2018 04; 11(4):587-601. Berg EL, Copping NA, Rivera JK, Pride MC, Careaga M, Bauman MD, Berman RF, Lein PJ, Harony-Nicolas H, Buxbaum JD, Ellegood J, Lerch JP, Wöhr M, Silverman JL. PMID: 29377611; PMCID: PMC5903935.
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    114. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun; 32(6):e4185. Chen X, Walter KM, Miller GW, Lein PJ, Puschner B. PMID: 29314156; PMCID: PMC5980666.
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    115. Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex. J Neuroinflammation. 2018 Jan 06; 15(1):7. Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ. PMID: 29306331; PMCID: PMC5756609.
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    116. Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3'-Dichlorobiphenyl (PCB 11). Toxics. 2017 Dec 23; 6(1). Sethi S, Keil KP, Lein PJ. PMID: 29295518; PMCID: PMC5874777.
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    119. In vivo and in vitro sex differences in the dendritic morphology of developing murine hippocampal and cortical neurons. Sci Rep. 2017 08 16; 7(1):8486. Keil KP, Sethi S, Wilson MD, Chen H, Lein PJ. PMID: 28814778; PMCID: PMC5559594.
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    120. Detection of 3,3'-Dichlorobiphenyl in Human Maternal Plasma and Its Effects on Axonal and Dendritic Growth in Primary Rat Neurons. Toxicol Sci. 2017 08 01; 158(2):401-411. Sethi S, Keil KP, Chen H, Hayakawa K, Li X, Lin Y, Lehmler HJ, Puschner B, Lein PJ. PMID: 28510766; PMCID: PMC5837364.
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    121. Editor's Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity. Toxicol Sci. 2017 07 01; 158(1):101-115. Kania-Korwel I, Lukasiewicz T, Barnhart CD, Stamou M, Chung H, Kelly KM, Bandiera S, Lein PJ, Lehmler HJ. PMID: 28431184; PMCID: PMC6070089.
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    122. A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. Aquat Toxicol. 2017 Sep; 190:1-10. Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. PMID: 28662416; PMCID: PMC5558850.
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    123. Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate. Toxicol Sci. 2017 06 01; 157(2):330-341. Sisó S, Hobson BA, Harvey DJ, Bruun DA, Rowland DJ, Garbow JR, Lein PJ. PMID: 28329845; PMCID: PMC6070115.
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    124. From the Cover: MagneticResonance Imaging Reveals Progressive Brain Injury in Rats Acutely Intoxicated With Diisopropylfluorophosphate. Toxicol Sci. 2017 06 01; 157(2):342-353. Hobson BA, Sisó S, Rowland DJ, Harvey DJ, Bruun DA, Garbow JR, Lein PJ. PMID: 28329842; PMCID: PMC5458789.
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    125. Mutant IDH1 and seizures in patients with glioma. Neurology. 2017 May 09; 88(19):1805-1813. Chen H, Judkins J, Thomas C, Wu M, Khoury L, Benjamin CG, Pacione D, Golfinos JG, Kumthekar P, Ghamsari F, Chen L, Lein P, Chetkovich DM, Snuderl M, Horbinski C. PMID: 28404805; PMCID: PMC5419985.
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    126. From the Cover: BDE-47 and BDE-49 Inhibit Axonal Growth in Primary Rat Hippocampal Neuron-Glia Co-Cultures via Ryanodine Receptor-Dependent Mechanisms. Toxicol Sci. 2017 04 01; 156(2):375-386. Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ. PMID: 28003438; PMCID: PMC6070026.
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    127. Nanostructure Introduces Artifacts in Quantitative Immunofluorescence by Influencing Fluorophore Intensity. Sci Rep. 2017 03 27; 7(1):427. Chapman CA, Zhu X, Chen H, Yanik AA, Lein PJ, Seker E. PMID: 28348397; PMCID: PMC5428417.
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    128. BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action. Sci Rep. 2017 03 20; 7:44861. Dach K, Bendt F, Huebenthal U, Giersiefer S, Lein PJ, Heuer H, Fritsche E. PMID: 28317842; PMCID: PMC5357893.
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    129. Neural mechanisms of functional impairment across the lifespan: The 15th Biennial Meeting of the International Neurotoxicology Association and 39th Annual Meeting of the Neurobehavioral Teratology Society. Neurotoxicology. 2017 03; 59:131-132. van Thriel C, Levin E, Lein P, Costa LG, Westerink RH. PMID: 28347437.
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    130. Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns. Stem Cells. 2017 04; 35(4):981-988. Dunaway K, Goorha S, Matelski L, Urraca N, Lein PJ, Korf I, Reiter LT, LaSalle JM. PMID: 28032673; PMCID: PMC5367950.
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    131. Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds. Front Neurosci. 2016; 10:590. Voorhees JR, Rohlman DS, Lein PJ, Pieper AA. PMID: 28149268; PMCID: PMC5241311.
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    132. Valid statistical approaches for analyzing sholl data: Mixed effects versus simple linear models. J Neurosci Methods. 2017 03 01; 279:33-43. Wilson MD, Sethi S, Lein PJ, Keil KP. PMID: 28104486; PMCID: PMC5346342.
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    133. Nanoporous Gold Biointerfaces: Modifying Nanostructure to Control Neural Cell Coverage and Enhance Electrophysiological Recording Performance. Adv Funct Mater. 2017 Jan 19; 27(3). Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ, Seker E. PMID: 28626362; PMCID: PMC5471629.
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    134. Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication. J Neuroinflammation. 2016 10 12; 13(1):267. Flannery BM, Bruun DA, Rowland DJ, Banks CN, Austin AT, Kukis DL, Li Y, Ford BD, Tancredi DJ, Silverman JL, Cherry SR, Lein PJ. PMID: 27733171; PMCID: PMC5062885.
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    135. Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents. Ann N Y Acad Sci. 2016 08; 1378(1):124-136. Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ. PMID: 27467073; PMCID: PMC5063690.
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    136. Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use. ALTEX. 2017; 34(1):49-74. Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, Hogberg HT, Leist M, Li A, Mundi WR, Padilla S, Piersma AH, Bal-Price A, Seiler A, Westerink RH, Zimmer B, Lein PJ. PMID: 27452664; PMCID: PMC5250586.
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    137. Mechanisms of Reduced Astrocyte Surface Coverage in Cortical Neuron-Glia Co-cultures on Nanoporous Gold Surfaces. Cell Mol Bioeng. 2016 Sep; 9(3):433-442. Chapman CA, Chen H, Stamou M, Lein PJ, Seker E. PMID: 27795742; PMCID: PMC5079442.
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    138. Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity. Neurotoxicology. 2017 03; 59:240-255. Bal-Price A, Lein PJ, Keil KP, Sethi S, Shafer T, Barenys M, Fritsche E, Sachana M, Meek MEB. PMID: 27212452; PMCID: PMC5114159.
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    139. Chasing the Elusive Benzofuran Impurity of the THR Antagonist NH-3: Synthesis, Isotope Labeling, and Biological Activity. J Org Chem. 2016 Mar 04; 81(5):1870-6. Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V. PMID: 26849160.
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    140. DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders? Environ Epigenet. 2016 Mar; 2(1). Keil KP, Lein PJ. PMID: 27158529; PMCID: PMC4856164.
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    141. BMP7-induced dendritic growth in sympathetic neurons requires p75(NTR) signaling. Dev Neurobiol. 2016 09; 76(9):1003-13. Courter LA, Shaffo FC, Ghogha A, Parrish DJ, Lorentz CU, Habecker BA, Lein PJ. PMID: 26663679; PMCID: PMC4905816.
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    142. Phenobarbital use and neurological problems in FMR1 premutation carriers. Neurotoxicology. 2016 Mar; 53:141-147. Saldarriaga W, Lein P, González Teshima LY, Isaza C, Rosa L, Polyak A, Hagerman R, Girirajan S, Silva M, Tassone F. PMID: 26802682; PMCID: PMC4808401.
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    143. Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides. Toxicology. 2016 Jan 18; 340:53-62. Lee YS, Lewis JA, Ippolito DL, Hussainzada N, Lein PJ, Jackson DA, Stallings JD. PMID: 26775027; PMCID: PMC4777610.
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    144. The influence of sensitization on mechanisms of organophosphorus pesticide-induced airway hyperreactivity. Am J Respir Cell Mol Biol. 2015 Nov; 53(5):738-47. Proskocil BJ, Bruun DA, Garg JA, Villagomez CC, Jacoby DB, Lein PJ, Fryer AD. PMID: 25897622; PMCID: PMC4742952.
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    145. Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio. BMC Genomics. 2015 Oct 24; 16:853. Bui-Nguyen TM, Baer CE, Lewis JA, Yang D, Lein PJ, Jackson DA. PMID: 26499117; PMCID: PMC4619386.
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    146. Subacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat. Toxicology. 2015 Dec 02; 338:59-68. Stamou M, Uwimana E, Flannery BM, Kania-Korwel I, Lehmler HJ, Lein PJ. PMID: 26463278; PMCID: PMC4658283.
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    147. Effect of pregnancy on the disposition of 2,2',3,5',6-pentachlorobiphenyl (PCB 95) atropisomers and their hydroxylated metabolites in female mice. Chem Res Toxicol. 2015 Sep 21; 28(9):1774-83. Kania-Korwel I, Barnhart CD, Lein PJ, Lehmler HJ. PMID: 26271003; PMCID: PMC4579038.
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    148. Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neurons. Mol Cell Neurosci. 2015 Jul; 67:116-25. Chandrasekaran V, Lea C, Sosa JC, Higgins D, Lein PJ. PMID: 26079955; PMCID: PMC4550485.
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    149. Using the Morris water maze to assess spatial learning and memory in weanling mice. PLoS One. 2015; 10(4):e0124521. Barnhart CD, Yang D, Lein PJ. PMID: 25886563; PMCID: PMC4401674.
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    150. Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures. Neuropharmacology. 2015 Aug; 95:332-42. Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ. PMID: 25882826; PMCID: PMC4466064.
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    151. Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury. J Neuroinflammation. 2015 Apr 02; 12:64. Li Y, Lein PJ, Ford GD, Liu C, Stovall KC, White TE, Bruun DA, Tewolde T, Gates AS, Distel TJ, Surles-Zeigler MC, Ford BD. PMID: 25880399; PMCID: PMC4391606.
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    152. Nanoporous gold as a neural interface coating: effects of topography, surface chemistry, and feature size. ACS Appl Mater Interfaces. 2015 Apr 08; 7(13):7093-100. Chapman CA, Chen H, Stamou M, Biener J, Biener MM, Lein PJ, Seker E. PMID: 25706691; PMCID: PMC4517587.
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    153. Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. Mol Brain. 2015 Feb 15; 8:10. Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ. PMID: 25757474; PMCID: PMC4339650.
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    154. Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture. Mol Pharmacol. 2015 Apr; 87(4):595-605. Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. PMID: 25583085; PMCID: PMC4366799.
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    155. Putative adverse outcome pathways relevant to neurotoxicity. Crit Rev Toxicol. 2015 Jan; 45(1):83-91. Bal-Price A, Crofton KM, Sachana M, Shafer TJ, Behl M, Forsby A, Hargreaves A, Landesmann B, Lein PJ, Louisse J, Monnet-Tschudi F, Paini A, Rolaki A, Schrattenholz A, Suñol C, van Thriel C, Whelan M, Fritsche E. PMID: 25605028; PMCID: PMC5072123.
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    156. Chapter 1 Overview of the Role of Environmental Factors in Neurodevelopmental Disorders. . 2015 Jan 1; 3-20. Lein LP. .
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    157. A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1β expression. J Pharmacol Exp Ther. 2015 Mar; 352(3):438-47. Grodzki AC, Poola B, Pasupuleti N, Nantz MH, Lein PJ, Gorin F. PMID: 25538105; PMCID: PMC4352593.
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    158. Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice. Environ Sci Technol. 2015 Jan 06; 49(1):616-25. Wu X, Barnhart C, Lein PJ, Lehmler HJ. PMID: 25420130; PMCID: PMC4291784.
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    159. High abundant protein removal from rodent blood for biomarker discovery. Biochem Biophys Res Commun. 2014 Dec 05; 455(1-2):84-9. Haudenschild DR, Eldridge A, Lein PJ, Chromy BA. PMID: 25445603; PMCID: PMC4309281.
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    160. Factors influencing adverse skin responses in rats receiving repeated subcutaneous injections and potential impact on neurobehavior. Curr Neurobiol. 2014 Dec 01; 5(1-2):1-10. Levoe SN, Flannery BM, Brignolo L, Imai DM, Koehne A, Austin AT, Bruun DA, Tancredi DJ, Lein PJ. PMID: 25705100; PMCID: PMC4334164.
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    161. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol. 2015 Jan-Feb; 47:36-45. Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ. PMID: 25446016; PMCID: PMC4291292.
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    162. Longitudinal assessment of occupational exposures to the organophosphorous insecticides chlorpyrifos and profenofos in Egyptian cotton field workers. Int J Hyg Environ Health. 2015 Mar; 218(2):203-11. Singleton ST, Lein PJ, Dadson OA, McGarrigle BP, Farahat FM, Farahat T, Bonner MR, Fenske RA, Galvin K, Lasarev MR, Anger WK, Rohlman DS, Olson JR. PMID: 25466362; PMCID: PMC4323691.
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    163. Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication. Toxicol Appl Pharmacol. 2014 Dec 01; 281(2):185-94. Vito ST, Austin AT, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, Tancredi DJ, Rogawski MA, Hammock BD, Lein PJ. PMID: 25448683; PMCID: PMC4258121.
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    164. Microcystins alter chemotactic behavior in Caenorhabditis elegans by selectively targeting the AWA sensory neuron. Toxins (Basel). 2014 Jun 10; 6(6):1813-36. Moore CE, Lein PJ, Puschner B. PMID: 24918360; PMCID: PMC4073131.
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    165. The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation. J Neurosci. 2014 Jan 15; 34(3):717-25. Lesiak A, Zhu M, Chen H, Appleyard SM, Impey S, Lein PJ, Wayman GA. PMID: 24431430; PMCID: PMC3891953.
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    166. PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicol Sci. 2014 Apr; 138(2):379-92. Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. PMID: 24385416; PMCID: PMC4007107.
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    167. Cytochrome p450 mRNA expression in the rodent brain: species-, sex-, and region-dependent differences. Drug Metab Dispos. 2014 Feb; 42(2):239-44. Stamou M, Wu X, Kania-Korwel I, Lehmler HJ, Lein PJ. PMID: 24255117; PMCID: PMC3912540.
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    168. Characterization of α-cypermethrin exposure in Egyptian agricultural workers. Int J Hyg Environ Health. 2014 Apr-May; 217(4-5):538-45. Singleton ST, Lein PJ, Farahat FM, Farahat T, Bonner MR, Knaak JB, Olson JR. PMID: 24269189; PMCID: PMC3972299.
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    169. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent. Xenobiotica. 2013 Nov; 43(11):933-47. Wu X, Kania-Korwel I, Chen H, Stamou M, Dammanahalli KJ, Duffel M, Lein PJ, Lehmler HJ. PMID: 23581876; PMCID: PMC3878182.
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    170. Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker. Toxicology. 2013 Apr 05; 306:35-9. Dadson OA, Ellison CA, Singleton ST, Chi LH, McGarrigle BP, Lein PJ, Farahat FM, Farahat T, Olson JR. PMID: 23415833; PMCID: PMC4751995.
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    171. Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. Am J Physiol Lung Cell Mol Physiol. 2013 Apr 15; 304(8):L519-29. Proskocil BJ, Bruun DA, Jacoby DB, van Rooijen N, Lein PJ, Fryer AD. PMID: 23377347; PMCID: PMC3625991.
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    172. Oxygen tension modulates differentiation and primary macrophage functions in the human monocytic THP-1 cell line. PLoS One. 2013; 8(1):e54926. Grodzki AC, Giulivi C, Lein PJ. PMID: 23355903; PMCID: PMC3552948.
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    173. Neuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum Disorders. Neurotoxicol Teratol. 2013 Mar-Apr; 36:3-16. Stamou M, Streifel KM, Goines PE, Lein PJ. PMID: 23269408; PMCID: PMC3610799.
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    174. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice. Environ Sci Technol. 2012 Oct 16; 46(20):11393-401. Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MH, Lein PJ, Veng-Pedersen P, Lehmler HJ. PMID: 22974126; PMCID: PMC3475189.
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    175. PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos. Toxicol Appl Pharmacol. 2012 Dec 15; 265(3):308-15. Ellison CA, Crane AL, Bonner MR, Knaak JB, Browne RW, Lein PJ, Olson JR. PMID: 22975224; PMCID: PMC3513664.
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    176. Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicol Sci. 2012 Dec; 130(2):362-72. Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. PMID: 22889812; PMCID: PMC3529644.
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    177. Spatiotemporal patterns of GFAP upregulation in rat brain following acute intoxication with diisopropylfluorophosphate (DFP). Curr Neurobiol. 2012 Jul; 3(2):90-97. Liu C, Li Y, Lein PJ, Ford BD. PMID: 24039349; PMCID: PMC3772776.
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    178. Neuregulin-1 is neuroprotective in a rat model of organophosphate-induced delayed neuronal injury. Toxicol Appl Pharmacol. 2012 Jul 15; 262(2):194-204. Li Y, Lein PJ, Liu C, Bruun DA, Giulivi C, Ford GD, Tewolde T, Ross-Inta C, Ford BD. PMID: 22583949; PMCID: PMC3607352.
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    179. PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environ Health Perspect. 2012 Jul; 120(7):997-1002. Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PMID: 22534141; PMCID: PMC3404670.
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    180. PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environ Health Perspect. 2012 Jul; 120(7):1003-9. Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PMID: 22534176; PMCID: PMC3404671.
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    181. Emerging concepts in neurotoxicology: models, mechanisms and modifying factors. Neurotoxicology. 2012 Jun; 33(3):516-7. Lein PJ. PMID: 22694846.
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    182. Developmental Neurotoxicity of Dioxins. . 2012 Apr 6; 193-227. Harry HG, Lein LP. .
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    183. Inducing dendritic growth in cultured sympathetic neurons. J Vis Exp. 2012 Mar 21; (61). Ghogha A, Bruun DA, Lein PJ. PMID: 22473299; PMCID: PMC3460579.
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    184. A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation. Neurotoxicology. 2012 Jun; 33(3):575-84. Banks CN, Lein PJ. PMID: 22342984; PMCID: PMC3358519.
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    185. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther. 2012 May; 341(2):435-46. Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. PMID: 22328574; PMCID: PMC3336809.
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    186. Experimental strategy for translational studies of organophosphorus pesticide neurotoxicity based on real-world occupational exposures to chlorpyrifos. Neurotoxicology. 2012 Aug; 33(4):660-8. Lein PJ, Bonner MR, Farahat FM, Olson JR, Rohlman DS, Fenske RA, Lattal KM, Lasarev MR, Galvin K, Farahat TM, Anger WK. PMID: 22240005; PMCID: PMC3332151.
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    187. Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. ALTEX. 2012; 29(2):202-15. Bal-Price AK, Coecke S, Costa L, Crofton KM, Fritsche E, Goldberg A, Grandjean P, Lein PJ, Li A, Lucchini R, Mundy WR, Padilla S, Persico AM, Seiler AE, Kreysa J. PMID: 22892558.
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    188. Allele and genotype frequencies of CYP2B6 and CYP2C19 polymorphisms in Egyptian agricultural workers. J Toxicol Environ Health A. 2012; 75(4):232-41. Ellison CA, Abou El-Ella SS, Tawfik M, Lein PJ, Olson JR. PMID: 22352331; PMCID: PMC3500531.
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    189. Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts. Neurotoxicology. 2012 Aug; 33(4):911-24. van Thriel C, Westerink RH, Beste C, Bale AS, Lein PJ, Leist M. PMID: 22008243; PMCID: PMC3288589.
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    190. Transcriptional responses of cultured rat sympathetic neurons during BMP-7-induced dendritic growth. PLoS One. 2011; 6(7):e21754. Garred MM, Wang MM, Guo X, Harrington CA, Lein PJ. PMID: 21765909; PMCID: PMC3135585.
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    191. Pharmacokinetics and pharmacodynamics of chlorpyrifos in adult male Long-Evans rats following repeated subcutaneous exposure to chlorpyrifos. Toxicology. 2011 Sep 05; 287(1-3):137-44. Ellison CA, Smith JN, Lein PJ, Olson JR. PMID: 21708215; PMCID: PMC3176336.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    192. Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication. Toxicol Appl Pharmacol. 2011 Jun 15; 253(3):261-9. Li Y, Lein PJ, Liu C, Bruun DA, Tewolde T, Ford G, Ford BD. PMID: 21513723; PMCID: PMC3108263.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    193. IFNγ Increases M2 Muscarinic Receptor Expression in Cultured Sympathetic Neurons. Curr Neurobiol. 2011 Apr; 2(1):23-29. Grodzki AC, Ghogha A, Mangini L, Fryer AD, Lein PJ. PMID: 23226931; PMCID: PMC3515643.
      View in: PubMed   Mentions: 5  
    194. Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior. Toxicol Sci. 2011 May; 121(1):146-59. Yang D, Lauridsen H, Buels K, Chi LH, La Du J, Bruun DA, Olson JR, Tanguay RL, Lein PJ. PMID: 21346248; PMCID: PMC3080187.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    195. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. J Neurochem. 2011 May; 117(4):632-42. Abdu E, Bruun DA, Yang D, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. PMID: 21155804; PMCID: PMC3081369.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    196. Exposure of the Developing Brain to Polychlorinated Biphenyls Influences the Susceptibility of the Adult Brain to Stress. . 2011 Jan 14; 211-229. Lein LP, Kim KK, Berman BR, Pessah PI. .
      View in: Publisher Site   Mentions:
    197. Biomarkers of chlorpyrifos exposure and effect in Egyptian cotton field workers. Environ Health Perspect. 2011 Jun; 119(6):801-6. Farahat FM, Ellison CA, Bonner MR, McGarrigle BP, Crane AL, Fenske RA, Lasarev MR, Rohlman DS, Anger WK, Lein PJ, Olson JR. PMID: 21224175; PMCID: PMC3114814.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsPHPublic Health
    198. Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals. ALTEX. 2011; 28(1):9-15. Crofton KM, Mundy WR, Lein PJ, Bal-Price A, Coecke S, Seiler AE, Knaut H, Buzanska L, Goldberg A. PMID: 21311847.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    199. Acute hippocampal slice preparation and hippocampal slice cultures. Methods Mol Biol. 2011; 758:115-34. Lein PJ, Barnhart CD, Pessah IN. PMID: 21815062; PMCID: PMC3499947.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    200. Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure. Neurotoxicology. 2011 Mar; 32(2):268-76. Rohlman DS, Anger WK, Lein PJ. PMID: 21182866; PMCID: PMC3057226.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansPHPublic Health
    201. Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environ Health Perspect. 2011 Apr; 119(4):519-26. Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. PMID: 21106467; PMCID: PMC3080935.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    202. Method for Shipping Live Cultures of Dissociated Rat Hippocampal Neurons. Curr Neurobiol. 2010 Oct; 1(2):95-98. Yang D, Bruun D, Andres DA, Lein PJ. PMID: 24052689; PMCID: PMC3775285.
      View in: PubMed   Mentions: 1  
    203. Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms. PLoS One. 2010 May 10; 5(5):e10562. Proskocil BJ, Bruun DA, Thompson CM, Fryer AD, Lein PJ. PMID: 20479945; PMCID: PMC2866713.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    204. Chlorpyrifos exposures in Egyptian cotton field workers. Neurotoxicology. 2010 Jun; 31(3):297-304. Farahat FM, Fenske RA, Olson JR, Galvin K, Bonner MR, Rohlman DS, Farahat TM, Lein PJ, Anger WK. PMID: 20193710; PMCID: PMC3580798.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    205. Polychlorinated biphenyls increase apoptosis in the developing rat brain. Curr Neurobiol. 2010 Mar; 1(1):70-76. Yang D, Lein PJ. PMID: 24052688; PMCID: PMC3775291.
      View in: PubMed   Mentions: 16  
    206. Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacol Ther. 2010 Feb; 125(2):260-85. Pessah IN, Cherednichenko G, Lein PJ. PMID: 19931307; PMCID: PMC2823855.
      View in: PubMed   Mentions: 128     Fields:    Translation:Humans
    207. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 2009 Sep; 30(5):811-21. Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. PMID: 19596370; PMCID: PMC3014989.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    208. Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation. J Neurochem. 2009 Feb; 108(4):1057-71. Kim WY, Gonsiorek EA, Barnhart C, Davare MA, Engebose AJ, Lauridsen H, Bruun D, Lesiak A, Wayman G, Bucelli R, Higgins D, Lein PJ. PMID: 19209406; PMCID: PMC4277848.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    209. Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation. J Neurochem. 2008 Dec; 107(5):1436-47. Andres DA, Shi GX, Bruun D, Barnhart C, Lein PJ. PMID: 18957053; PMCID: PMC2857931.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    210. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environ Health Perspect. 2009 Mar; 117(3):426-35. Yang D, Kim KH, Phimister A, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PR, Anderson KA, Wayman G, Pessah IN, Lein PJ. PMID: 19337518; PMCID: PMC2661913.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    211. Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells. Mol Biol Cell. 2008 Jun; 19(6):2631-41. Boswell BA, Lein PJ, Musil LS. PMID: 18400943; PMCID: PMC2397318.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    212. Developmental exposure to polychlorinated biphenyls influences stroke outcome in adult rats. Environ Health Perspect. 2008 Apr; 116(4):474-80. Dziennis S, Yang D, Cheng J, Anderson KA, Alkayed NJ, Hurn PD, Lein PJ. PMID: 18414629; PMCID: PMC2291013.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsPHPublic Health
    213. Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity. Environ Health Perspect. 2008 Mar; 116(3):381-8. Proskocil BJ, Bruun DA, Lorton JK, Blensly KC, Jacoby DB, Lein PJ, Fryer AD. PMID: 18335107; PMCID: PMC2265045.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsPHPublic Health
    214. Immunologic and neurodevelopmental susceptibilities of autism. Neurotoxicology. 2008 May; 29(3):532-45. Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. PMID: 18394707; PMCID: PMC2475601.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsPHPublic Health
    215. Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons. J Pharmacol Exp Ther. 2008 Mar; 324(3):1172-80. Bucelli RC, Gonsiorek EA, Kim WY, Bruun D, Rabin RA, Higgins D, Lein PJ. PMID: 18079356.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    216. Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase. Toxicol Appl Pharmacol. 2008 Apr 01; 228(1):32-41. Yang D, Howard A, Bruun D, Ajua-Alemanj M, Pickart C, Lein PJ. PMID: 18076960; PMCID: PMC2408880.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    217. The novel GTPase Rit differentially regulates axonal and dendritic growth. J Neurosci. 2007 Apr 25; 27(17):4725-36. Lein PJ, Guo X, Shi GX, Moholt-Siebert M, Bruun D, Andres DA. PMID: 17460085; PMCID: PMC3495986.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    218. Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies. Environ Health Perspect. 2007 Jun; 115(6):924-31. Coecke S, Goldberg AM, Allen S, Buzanska L, Calamandrei G, Crofton K, Hareng L, Hartung T, Knaut H, Honegger P, Jacobs M, Lein P, Li A, Mundy W, Owen D, Schneider S, Silbergeld E, Reum T, Trnovec T, Monnet-Tschudi F, Bal-Price A. PMID: 17589601; PMCID: PMC1892131.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    219. Meeting report: alternatives for developmental neurotoxicity testing. Environ Health Perspect. 2007 May; 115(5):764-8. Lein P, Locke P, Goldberg A. PMID: 17520065; PMCID: PMC1867989.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    220. Ontogenetic alterations in molecular and structural correlates of dendritic growth after developmental exposure to polychlorinated biphenyls. Environ Health Perspect. 2007 Apr; 115(4):556-63. Lein PJ, Yang D, Bachstetter AD, Tilson HA, Harry GJ, Mervis RF, Kodavanti PR. PMID: 17450224; PMCID: PMC1852648.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    221. Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism. J Neurochem. 2006 Mar; 96(5):1253-66. Pin S, Chen H, Lein PJ, Wang MM. PMID: 16441515.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    222. CHAPTER 17 Noncholinesterase Mechanisms of Central and Peripheral Neurotoxicity: Muscarinic Receptors and Other Targets. . 2006 Jan 1; 233-245. JETT JD, LEIN LP. .
      View in: Publisher Site   Mentions:
    223. Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures. Toxicol Appl Pharmacol. 2005 Sep 01; 207(2):112-24. Howard AS, Bucelli R, Jett DA, Bruun D, Yang D, Lein PJ. PMID: 16102564.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    224. In vitro and other alternative approaches to developmental neurotoxicity testing (DNT). Environ Toxicol Pharmacol. 2005 May; 19(3):735-44. Lein P, Silbergeld E, Locke P, Goldberg AM. PMID: 21783550.
      View in: PubMed   Mentions: 38     Fields:    
    225. Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition. Toxicol Sci. 2005 Jan; 83(1):166-76. Lein PJ, Fryer AD. PMID: 15470232.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    226. Bone morphogenetic proteins regulate ionotropic glutamate receptors in human retina. Eur J Neurosci. 2004 Oct; 20(8):2031-7. Shen W, Finnegan S, Lein P, Sullivan S, Slaughter M, Higgins D. PMID: 15450082.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    227. Extracellular signal-regulated kinases regulate dendritic growth in rat sympathetic neurons. J Neurosci. 2004 Mar 31; 24(13):3304-12. Kim IJ, Drahushuk KM, Kim WY, Gonsiorek EA, Lein P, Andres DA, Higgins D. PMID: 15056710; PMCID: PMC6730016.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    228. Mechanisms of organophosphate insecticide-induced airway hyperreactivity. Am J Physiol Lung Cell Mol Physiol. 2004 May; 286(5):L963-9. Fryer AD, Lein PJ, Howard AS, Yost BL, Beckles RA, Jett DA. PMID: 14704222.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    229. Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals. Brain Res. 2003 Dec 19; 994(1):81-90. Chen HL, Lein PJ, Wang JY, Gash D, Hoffer BJ, Chiang YH. PMID: 14642451.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    230. Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor. Toxicol Appl Pharmacol. 2003 Jul 01; 190(1):72-86. Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. PMID: 12831785.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    231. Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke. 2003 Feb; 34(2):558-64. Chang CF, Lin SZ, Chiang YH, Morales M, Chou J, Lein P, Chen HL, Hoffer BJ, Wang Y. PMID: 12574575.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    232. Glia induce dendritic growth in cultured sympathetic neurons by modulating the balance between bone morphogenetic proteins (BMPs) and BMP antagonists. J Neurosci. 2002 Dec 01; 22(23):10377-87. Lein PJ, Beck HN, Chandrasekaran V, Gallagher PJ, Chen HL, Lin Y, Guo X, Kaplan PL, Tiedge H, Higgins D. PMID: 12451137; PMCID: PMC6758753.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    233. Noncholinesterase mechanisms of chlorpyrifos neurotoxicity: altered phosphorylation of Ca2+/cAMP response element binding protein in cultured neurons. Toxicol Appl Pharmacol. 2002 Jul 15; 182(2):176-85. Schuh RA, Lein PJ, Beckles RA, Jett DA. PMID: 12140181.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    234. Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation. Neurotoxicology. 2002 Jul; 23(2):147-57. Roth JA, Horbinski C, Higgins D, Lein P, Garrick MD. PMID: 12224755.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    235. Interferon gamma induces retrograde dendritic retraction and inhibits synapse formation. J Neurosci. 2002 Jun 01; 22(11):4530-9. Kim IJ, Beck HN, Lein PJ, Higgins D. PMID: 12040060; PMCID: PMC6758811.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    236. Cerebrospinal fluid contains biologically active bone morphogenetic protein-7. Exp Neurol. 2001 Dec; 172(2):273-81. Dattatreyamurty B, Roux E, Horbinski C, Kaplan PL, Robak LA, Beck HN, Lein P, Higgins D, Chandrasekaran V. PMID: 11716552.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    237. Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. BMC Neurosci. 2001; 2:12. Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ. PMID: 11580864; PMCID: PMC56999.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    238. Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity. J Neurobiol. 2001 Aug; 48(2):120-30. Guo X, Lin Y, Horbinski C, Drahushuk KM, Kim IJ, Kaplan PL, Lein P, Wang T, Higgins D. PMID: 11438941.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    239. Manganese induces neurite outgrowth in PC12 cells via upregulation of alpha(v) integrins. Brain Res. 2000 Dec 08; 885(2):220-30. Lein P, Gallagher PJ, Amodeo J, Howie H, Roth JA. PMID: 11102576.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    240. Leukemia inhibitory factor and ciliary neurotrophic factor cause dendritic retraction in cultured rat sympathetic neurons. J Neurosci. 1999 Mar 15; 19(6):2113-21. Guo X, Chandrasekaran V, Lein P, Kaplan PL, Higgins D. PMID: 10066264; PMCID: PMC6782564.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    241. Effect of leukemia inhibitory factor (LIF) on the morphology and survival of cultured hippocampal neurons and glial cells. Brain Res. 1998 Jul 06; 798(1-2):140-6. Gadient RA, Lein P, Higgins D, Patterson PH. PMID: 9666105.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    242. Leukemia inhibitory factor and ciliary neurotrophic factor regulate dendritic growth in cultures of rat sympathetic neurons. Brain Res Dev Brain Res. 1997 Dec 19; 104(1-2):101-10. Guo X, Metzler-Northrup J, Lein P, Rueger D, Higgins D. PMID: 9466712.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    243. Mechanisms of neuronal polarity. Curr Opin Neurobiol. 1997 Oct; 7(5):599-604. Higgins D, Burack M, Lein P, Banker G. PMID: 9384542.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    244. The effects of extracellular matrix and osteogenic protein-1 on the morphological differentiation of rat sympathetic neurons. Int J Dev Neurosci. 1996 Jun; 14(3):203-15. Lein P, Guo X, Hedges AM, Rueger D, Johnson M, Higgins D. PMID: 8842799.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    245. Antibodies to β1 integrins inhibit dendritic growth in rat sympathetic neurons. Biomed Res (Aligarh). 1996; 7(1):101-111. Lein P, Higgins D. PMID: 29238133; PMCID: PMC5724964.
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    246. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons. Neuron. 1995 Sep; 15(3):597-605. Lein P, Johnson M, Guo X, Rueger D, Higgins D. PMID: 7546739.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    247. Laminin selectively enhances axonal growth and accelerates the development of polarity by hippocampal neurons in culture. Brain Res Dev Brain Res. 1992 Oct 23; 69(2):191-7. Lein PJ, Banker GA, Higgins D. PMID: 1424096.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    248. Protein synthesis is required for the initiation of dendritic growth in embryonic rat sympathetic neurons in vitro. Brain Res Dev Brain Res. 1991 Jun 21; 60(2):187-96. Lein PJ, Higgins D. PMID: 1716531.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    249. The NC1 domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin. J Cell Biol. 1991 Apr; 113(2):417-28. Lein PJ, Higgins D, Turner DC, Flier LA, Terranova VP. PMID: 2010469; PMCID: PMC2288935.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    250. Distinct spatial localization of specific mRNAs in cultured sympathetic neurons. Neuron. 1990 Dec; 5(6):809-19. Bruckenstein DA, Lein PJ, Higgins D, Fremeau RT. PMID: 2148487.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    251. Laminin and a basement membrane extract have different effects on axonal and dendritic outgrowth from embryonic rat sympathetic neurons in vitro. Dev Biol. 1989 Dec; 136(2):330-45. Lein PJ, Higgins D. PMID: 2479584.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    252. Effect of short-term exposure to hexachlorophene on rat brain cell specific marker enzymes. Fundam Appl Toxicol. 1988 Oct; 11(3):519-27. Kung MP, Nickerson PA, Sansone FM, Olson JR, Kostyniak PJ, Adolf MA, Lein PJ, Roth JA. PMID: 2906023.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    253. Mutagenic activity of surface waters adjacent to a nuclear fuel processing facility. Arch Environ Contam Toxicol. 1987 Sep; 16(5):531-7. Pancorbo OC, Lein PJ, Blevins RD. PMID: 3632040.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
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