Edward S Schelegle

Title(s)Professor, School of Veterinary Medicine
SchoolUniversity of California, Davis
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    1. Exhaled breath condensate profiles of U.S. Navy divers following prolonged hyperbaric oxygen (HBO) and nitrogen-oxygen (Nitrox) chamber exposures. J Breath Res. 2023 06 12; 17(3). Fothergill DM, Borras E, McCartney MM, Schelegle ES, Davis CE. PMID: 37207635.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. Novel LC-MS-TOF method to detect and quantify ascorbic and uric acid simultaneously in different biological matrices. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Apr 01; 1168:122588. Borras E, Schrumpf L, Stephens N, Weimer BC, Davis CE, Schelegle ES. PMID: 33690092; PMCID: PMC9303055.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    3. Comparison of nonparametric and parametric methods for time-frequency heart rate variability analysis in a rodent model of cardiovascular disease. PLoS One. 2020; 15(11):e0242147. Wong EM, Tablin F, Schelegle ES. PMID: 33166366; PMCID: PMC7652293.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. Organized lymphatic tissue (BALT) in lungs of rhesus monkeys after air pollutant exposure. Anat Rec (Hoboken). 2020 11; 303(11):2766-2773. Pabst R, Miller LA, Schelegle E, Hyde DM. PMID: 32445535; PMCID: PMC8793891.
      View in: PubMed   Mentions: 1     Fields:    
    5. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats. Toxicol Sci. 2018 09 01; 165(1):244-253. Shaffo FC, Grodzki AC, Schelegle ES, Lein PJ. PMID: 29939342; PMCID: PMC6135637.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    6. Ultrafine Particulate Matter Combined With Ozone Exacerbates Lung Injury in Mature Adult Rats With Cardiovascular Disease. Toxicol Sci. 2018 05 01; 163(1):140-151. Wong EM, Walby WF, Wilson DW, Tablin F, Schelegle ES. PMID: 29394414; PMCID: PMC5920298.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsPHPublic Health
    7. Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. ILAR J. 2017 12 01; 58(2):269-280. Miller LA, Royer CM, Pinkerton KE, Schelegle ES. PMID: 29216343; PMCID: PMC5886323.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    8. Early life allergen and air pollutant exposures alter longitudinal blood immune profiles in infant rhesus monkeys. Toxicol Appl Pharmacol. 2017 08 01; 328:60-69. Crowley CM, Fontaine JH, Gerriets JE, Schelegle ES, Hyde DM, Miller LA. PMID: 28529118; PMCID: PMC5535809.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    9. Early Life Wildfire Smoke Exposure Is Associated with Immune Dysregulation and Lung Function Decrements in Adolescence. Am J Respir Cell Mol Biol. 2017 05; 56(5):657-666. Black C, Gerriets JE, Fontaine JH, Harper RW, Kenyon NJ, Tablin F, Schelegle ES, Miller LA. PMID: 28208028; PMCID: PMC5449494.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCellsPHPublic Health
    10. SMAD Signaling in the Airways of Healthy Rhesus Macaques versus Rhesus Macaques with Asthma Highlights a Relationship Between Inflammation and Bone Morphogenetic Proteins. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):562-73. Lynn TM, Molloy EL, Masterson JC, Glynn SF, Costello RW, Avdalovic MV, Schelegle ES, Miller LA, Hyde DM, O'Dea S. PMID: 26414797; PMCID: PMC4821057.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Exhaled volatile organic compounds in individuals with a history of high altitude pulmonary edema and varying hypoxia-induced responses. J Breath Res. 2015 Apr 20; 9(2):026004. Figueroa JA, Mansoor JK, Allen RP, Davis CE, Walby WF, Aksenov AA, Zhao W, Lewis WR, Schelegle ES. PMID: 25891856.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Early life exposure to allergen and ozone results in altered development in adolescent rhesus macaque lungs. Toxicol Appl Pharmacol. 2015 Feb 15; 283(1):35-41. Herring MJ, Putney LF, St George JA, Avdalovic MV, Schelegle ES, Miller LA, Hyde DM. PMID: 25545987; PMCID: PMC5922427.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    13. Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15; 307(6):L471-81. Murphy SR, Oslund KL, Hyde DM, Miller LA, Van Winkle LS, Schelegle ES. PMID: 25063800; PMCID: PMC4166783.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. Persistence of serotonergic enhancement of airway response in a model of childhood asthma. Am J Respir Cell Mol Biol. 2014 Jul; 51(1):77-85. Moore BD, Hyde DM, Miller LA, Wong EM, Schelegle ES. PMID: 24484440; PMCID: PMC4091858.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    15. Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H405-17. Allen RP, Schelegle ES, Bennett SH. PMID: 24858853; PMCID: PMC4121648.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension. PLoS One. 2014; 9(4):e95331. Mansoor JK, Schelegle ES, Davis CE, Walby WF, Zhao W, Aksenov AA, Pasamontes A, Figueroa J, Allen R. PMID: 24748102; PMCID: PMC3991617.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    17. Behavioral inhibition in rhesus monkeys (Macaca mulatta) is related to the airways response, but not immune measures, commonly associated with asthma. PLoS One. 2013; 8(8):e71575. Chun K, Miller LA, Schelegle ES, Hyde DM, Capitanio JP. PMID: 23951195; PMCID: PMC3739724.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    18. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicol Sci. 2013 Jul; 134(1):168-79. Murphy SR, Schelegle ES, Miller LA, Hyde DM, Van Winkle LS. PMID: 23570994; PMCID: PMC3693130.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    19. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. Eur Respir J. 2013 Aug; 42(2):350-61. Davis BB, Zeki AA, Bratt JM, Wang L, Filosto S, Walby WF, Kenyon NJ, Goldkorn T, Schelegle ES, Pinkerton KE. PMID: 23180589; PMCID: PMC6082623.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    20. Development of a rhesus monkey lung geometry model and application to particle deposition in comparison to humans. Inhal Toxicol. 2012 Nov; 24(13):869-99. Asgharian B, Price O, McClellan G, Corley R, Einstein DR, Jacob RE, Harkema J, Carey SA, Schelegle E, Hyde D, Kimbell JS, Miller FJ. PMID: 23121298; PMCID: PMC5119470.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    21. Postnatal exposure history and airways: oxidant stress responses in airway explants. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):815-23. Murphy SR, Schelegle ES, Edwards PC, Miller LA, Hyde DM, Van Winkle LS. PMID: 22962062; PMCID: PMC3547096.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    22. Ozone exposure during the early postnatal period alters the timing and pattern of alveolar growth and development in nonhuman primates. Anat Rec (Hoboken). 2012 Oct; 295(10):1707-16. Avdalovic MV, Tyler NK, Putney L, Nishio SJ, Quesenberry S, Singh PJ, Miller LA, Schelegle ES, Plopper CG, Vu T, Hyde DM. PMID: 22887719; PMCID: PMC5462601.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsPHPublic Health
    23. Prediction of lung function response for populations exposed to a wide range of ozone conditions. Inhal Toxicol. 2012 Aug; 24(10):619-33. McDonnell WF, Stewart PW, Smith MV, Kim CS, Schelegle ES. PMID: 22906168.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    24. Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clin Exp Allergy. 2012 Jul; 42(7):1104-18. Plopper CG, Joad JP, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Lasley WL, Buckpitt AR, Pinkerton KE, Tarkington BK, Davis S, Nishio SJ, Gershwin LJ, Wu R, Hyde DM. PMID: 22702509; PMCID: PMC3913647.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    25. Modelling of individual subject ozone exposure response kinetics. Inhal Toxicol. 2012 Jun; 24(7):401-15. Schelegle ES, Adams WC, Walby WF, Marion MS. PMID: 22642289.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    26. Allergen and ozone exacerbate serotonin-induced increases in airway smooth muscle contraction in a model of childhood asthma. Respiration. 2012; 83(6):529-42. Moore BD, Hyde D, Miller L, Wong E, Frelinger J, Schelegle ES. PMID: 22507883; PMCID: PMC7068792.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    27. Vagal afferents contribute to exacerbated airway responses following ozone and allergen challenge. Respir Physiol Neurobiol. 2012 May 31; 181(3):277-85. Schelegle ES, Walby WF. PMID: 22525484; PMCID: PMC3366056.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    28. Increased CCL24/eotaxin-2 with postnatal ozone exposure in allergen-sensitized infant monkeys is not associated with recruitment of eosinophils to airway mucosa. Toxicol Appl Pharmacol. 2011 Dec 15; 257(3):309-18. Chou DL, Gerriets JE, Schelegle ES, Hyde DM, Miller LA. PMID: 21945493; PMCID: PMC3226879.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    29. Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model. Am J Pathol. 2011 Oct; 179(4):1667-80. Abbas AR, Jackman JK, Bullens SL, Davis SM, Choy DF, Fedorowicz G, Tan M, Truong BT, Gloria Meng Y, Diehl L, Miller LA, Schelegle ES, Hyde DM, Clark HF, Modrusan Z, Arron JR, Wu LC. PMID: 21819959; PMCID: PMC3181391.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    30. Behavioral inhibition is associated with airway hyperresponsiveness but not atopy in a monkey model of asthma. Psychosom Med. 2011 May; 73(4):288-94. Capitanio JP, Miller LA, Schelegle ES, Mendoza SP, Mason WA, Hyde DM. PMID: 21536834; PMCID: PMC3090450.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    31. Small particles disrupt postnatal airway development. J Appl Physiol (1985). 2010 Oct; 109(4):1115-24. Lee D, Wallis C, Wexler AS, Schelegle ES, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer B, Kennedy IM, Chan JK. PMID: 20634362; PMCID: PMC4182294.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsPHPublic Health
    32. Airway mast cells in a rhesus model of childhood allergic airways disease. Toxicol Sci. 2010 Jul; 116(1):313-22. Van Winkle LS, Baker GL, Chan JK, Schelegle ES, Plopper CG. PMID: 20403968; PMCID: PMC2886865.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    33. Activation of calcitonin gene-related peptide receptor during ozone inhalation contributes to airway epithelial injury and repair. Toxicol Pathol. 2009 Oct; 37(6):805-13. Oslund KL, Hyde DM, Putney LF, Alfaro MF, Walby WF, Tyler NK, Schelegle ES. PMID: 19700657.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. 6.6-hour inhalation of ozone concentrations from 60 to 87 parts per billion in healthy humans. Am J Respir Crit Care Med. 2009 Aug 01; 180(3):265-72. Schelegle ES, Morales CA, Walby WF, Marion S, Allen RP. PMID: 19447899.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic Health
    35. Ozone and allergen exposure during postnatal development alters the frequency and airway distribution of CD25+ cells in infant rhesus monkeys. Toxicol Appl Pharmacol. 2009 Apr 01; 236(1):39-48. Miller LA, Gerriets JE, Tyler NK, Abel K, Schelegle ES, Plopper CG, Hyde DM. PMID: 19371618; PMCID: PMC2670960.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    36. Primate Models of Allergic Asthma. . 2008 Jul 25; 1185-1201. Plopper PC, Smiley-Jewell SS, Miller ML, Fanucchi FM, Evans EM, Buckpitt BA, Avdalovic AM, Gershwin GL, Joad JJ, Kajekar KR, Larson LS, Pinkerton PK, Van Winkle VL, Schelegle SE, Pieczarka PE, Wu WR, Hyde HD. .
      View in: Publisher Site   Mentions:
    37. Activation of neurokinin-1 receptors during ozone inhalation contributes to epithelial injury and repair. Am J Respir Cell Mol Biol. 2008 Sep; 39(3):279-88. Oslund KL, Hyde DM, Putney LF, Alfaro MF, Walby WF, Tyler NK, Schelegle ES. PMID: 18390473; PMCID: PMC2542446.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    38. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J Clin Invest. 2007 Dec; 117(12):3868-78. Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC, Hymowitz SG, Martin F. PMID: 18060034; PMCID: PMC2096422.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    39. The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone. Toxicol Appl Pharmacol. 2008 Jan 15; 226(2):153-60. Joad JP, Kott KS, Bric JM, Schelegle ES, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE. PMID: 17991502.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    40. Breath condensate levels of 8-isoprostane and leukotriene B4 after ozone inhalation are greater in sensitive versus nonsensitive subjects. Exp Lung Res. 2007 Apr-May; 33(3-4):115-33. Alfaro MF, Walby WF, Adams WC, Schelegle ES. PMID: 17558675.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    41. Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology? Toxicol Pathol. 2007 Jan; 35(1):97-110. Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM. PMID: 17325978.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsPHPublic Health
    42. Time course of ozone-induced changes in breathing pattern in healthy exercising humans. J Appl Physiol (1985). 2007 Feb; 102(2):688-97. Schelegle ES, Walby WF, Adams WC. PMID: 17082379.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma. Pulm Pharmacol Ther. 2007; 20(6):660-8. Mansoor JK, Decile KC, Giri SN, Pinkerton KE, Walby WF, Bratt JM, Grewal H, Margolin SB, Schelegle ES. PMID: 17049446.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    44. Vascular remodeling is airway generation-specific in a primate model of chronic asthma. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1069-76. Avdalovic MV, Putney LF, Schelegle ES, Miller L, Usachenko JL, Tyler NK, Plopper CG, Gershwin LJ, Hyde DM. PMID: 16931639; PMCID: PMC2648107.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    45. Cyclic exposure to ozone alters distal airway development in infant rhesus monkeys. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L644-50. Fanucchi MV, Plopper CG, Evans MJ, Hyde DM, Van Winkle LS, Gershwin LJ, Schelegle ES. PMID: 16648242.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    46. Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium. Respir Physiol Neurobiol. 2007 Jan 15; 155(1):55-63. Kajekar R, Pieczarka EM, Smiley-Jewell SM, Schelegle ES, Fanucchi MV, Plopper CG. PMID: 16616710.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    47. Deep-breath frequency in bronchoconstricted monkeys (Macaca fascicularis). J Appl Physiol (1985). 2006 Mar; 100(3):786-91. Dybas JM, Andresen CJ, Schelegle ES, McCue RW, Callender NN, Jackson AC. PMID: 16467390.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    48. Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone. Toxicol Appl Pharmacol. 2006 Aug 01; 214(3):237-43. Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle ES, Gershwin LJ, Pinkerton KE. PMID: 16466656.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCellsPHPublic Health
    49. Rush immunotherapy in an experimental model of feline allergic asthma. Vet Immunol Immunopathol. 2006 Mar 15; 110(1-2):141-53. Reinero CR, Byerly JR, Berghaus RD, Berghaus LJ, Schelegle ES, Hyde DM, Gershwin LJ. PMID: 16325921.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    50. Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma. Am J Vet Res. 2005 Jul; 66(7):1121-7. Reinero CR, Decile KC, Byerly JR, Berghaus RD, Walby WE, Berghaus LJ, Hyde DM, Schelegle ES, Gershwin LJ. PMID: 16111148.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCTClinical Trials
    51. Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys. Clin Exp Allergy. 2005 Jul; 35(7):894-906. Miller LA, Hurst SD, Coffman RL, Tyler NK, Stovall MY, Chou DL, Putney LF, Gershwin LJ, Schelegle ES, Plopper CG, Hyde DM. PMID: 16008676; PMCID: PMC3918236.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    52. Chronic aeroallergen during infancy enhances eotaxin-3 expression in airway epithelium and nerves. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):1-8. Chou DL, Daugherty BL, McKenna EK, Hsu WM, Tyler NK, Plopper CG, Hyde DM, Schelegle ES, Gershwin LJ, Miller LA. PMID: 15834047; PMCID: PMC2715301.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    53. L-arginine supplementation enhances exhaled NO, breath condensate VEGF, and headache at 4,342 m. High Alt Med Biol. 2005; 6(4):289-300. Mansoor JK, Morrissey BM, Walby WF, Yoneda KY, Juarez M, Kajekar R, Severinghaus JW, Eldridge MW, Schelegle ES. PMID: 16351563.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    54. Smooth muscle hypertrophy in distal airways of sensitized infant rhesus monkeys exposed to house dust mite allergen. Clin Exp Allergy. 2004 Oct; 34(10):1627-33. Tran MU, Weir AJ, Fanucchi MV, Rodriguez AE, Pantle LM, Smiley-Jewell SM, Van Winkle LS, Evans MJ, Miller LA, Schelegle ES, Gershwin LJ, Hyde DM, Plopper CG. PMID: 15479280.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    55. Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys. J Appl Physiol (1985). 2004 Dec; 97(6):2364-71; discussion 2354. Tran MU, Weir AJ, Fanucchi MV, Murphy AE, Van Winkle LS, Evans MJ, Smiley-Jewell SM, Miller L, Schelegle ES, Gershwin LJ, Hyde DM, Plopper CG. PMID: 15347627.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    56. An experimental model of allergic asthma in cats sensitized to house dust mite or bermuda grass allergen. Int Arch Allergy Immunol. 2004 Oct; 135(2):117-31. Norris Reinero CR, Decile KC, Berghaus RD, Williams KJ, Leutenegger CM, Walby WF, Schelegle ES, Hyde DM, Gershwin LJ. PMID: 15345910.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    57. Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys. Am J Respir Crit Care Med. 2004 Dec 01; 170(11):1153-7. Fanucchi MV, Schelegle ES, Baker GL, Evans MJ, McDonald RJ, Gershwin LJ, Raz E, Hyde DM, Plopper CG, Miller LA. PMID: 15306532; PMCID: PMC3927836.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    58. Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development. J Appl Physiol (1985). 2004 Dec; 97(6):2355-63; discussion 2354. Van Winkle LS, Fanucchi MV, Miller LA, Baker GL, Gershwin LJ, Schelegle ES, Hyde DM, Evans MJ, Plopper CG. PMID: 15298983.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    59. The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery. Clin Exp Allergy. 2004 Jul; 34(7):1131-6. Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle ES, Gershwin LJ, Miller LA, Hyde DM, Plopper CG. PMID: 15248862.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    60. Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide. Am J Physiol Lung Cell Mol Physiol. 2004 Aug; 287(2):L286-95. Larson SD, Plopper CG, Baker G, Tarkington BK, Decile KC, Pinkerton K, Mansoor JK, Hyde DM, Schelegle ES. PMID: 15064227.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    61. Postnatal remodeling of the neural components of the epithelial-mesenchymal trophic unit in the proximal airways of infant rhesus monkeys exposed to ozone and allergen. Toxicol Appl Pharmacol. 2004 Feb 01; 194(3):211-20. Larson SD, Schelegle ES, Walby WF, Gershwin LJ, Fanuccihi MV, Evans MJ, Joad JP, Tarkington BK, Hyde DM, Plopper CG. PMID: 14761677.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    62. Effect of rapid shallow breathing on the distribution of 18O-labeled ozone reaction product in the respiratory tract of the rat. Inhal Toxicol. 2004 Feb; 16(2):77-85. Alfaro MF, Putney L, Tarkington BK, Hatch GE, Hyde DM, Schelegle ES. PMID: 15204780.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    63. Allergen-specific IgG and IgA in serum and bronchoalveolar lavage fluid in a model of experimental feline asthma. Vet Immunol Immunopathol. 2003 Dec 15; 96(3-4):119-27. Norris CR, Byerly JR, Decile KC, Berghaus RD, Walby WF, Schelegle ES, Hyde DM, Gershwin LJ. PMID: 14592725.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    64. Production of polyclonal antisera against feline immunoglobulin E and its use in an ELISA in cats with experimentally induced asthma. Vet Immunol Immunopathol. 2003 Dec 15; 96(3-4):149-57. Norris CR, Decile KC, Byerly JR, Berghaus RD, Schelegle ES, Hyde DM, Gershwin LJ. PMID: 14592728.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    65. Immune and airway effects of house dust mite aeroallergen exposures during postnatal development of the infant rhesus monkey. Clin Exp Allergy. 2003 Dec; 33(12):1686-94. Miller LA, Plopper CG, Hyde DM, Gerriets JE, Pieczarka EM, Tyler NK, Evans MJ, Gershwin LJ, Schelegle ES, Van Winkle LS. PMID: 14656356.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    66. Concentrations of cysteinyl leukotrienes in urine and bronchoalveolar lavage fluid of cats with experimentally induced asthma. Am J Vet Res. 2003 Nov; 64(11):1449-53. Norris CR, Decile KC, Berghaus LJ, Berghaus RD, Walby WF, Schelegle ES, Hyde DM, Gershwin LJ. PMID: 14620784.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    67. Amelioration of doxorubicin-induced cardiac and renal toxicity by pirfenidone in rats. Cancer Chemother Pharmacol. 2004 Feb; 53(2):141-50. Giri SN, Al-Bayati MA, Du X, Schelegle E, Mohr FC, Margolin SB. PMID: 14564477.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    68. Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicol Appl Pharmacol. 2003 Aug 15; 191(1):74-85. Schelegle ES, Miller LA, Gershwin LJ, Fanucchi MV, Van Winkle LS, Gerriets JE, Walby WF, Mitchell V, Tarkington BK, Wong VJ, Baker GL, Pantle LM, Joad JP, Pinkerton KE, Wu R, Evans MJ, Hyde DM, Plopper CG. PMID: 12915105.
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    69. Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L931-9. Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle ES, Gershwin LJ, Miller LA, Hyde DM, Sannes PL, Plopper CG. PMID: 12832283.
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    70. Pathogenesis of mucous cell metaplasia in a murine asthma model. Am J Pathol. 2003 Jun; 162(6):2069-78. Reader JR, Tepper JS, Schelegle ES, Aldrich MC, Putney LF, Pfeiffer JW, Hyde DM. PMID: 12759261; PMCID: PMC2216702.
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    71. Interleukin-9 induces mucous cell metaplasia independent of inflammation. Am J Respir Cell Mol Biol. 2003 Jun; 28(6):664-72. Reader JR, Hyde DM, Schelegle ES, Aldrich MC, Stoddard AM, McLane MP, Levitt RC, Tepper JS. PMID: 12760964.
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    72. The three-dimensional distribution of nerves along the entire intrapulmonary airway tree of the adult rat and the anatomical relationship between nerves and neuroepithelial bodies. Am J Respir Cell Mol Biol. 2003 May; 28(5):592-9. Larson SD, Schelegle ES, Hyde DM, Plopper CG. PMID: 12707015.
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    73. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol. 2003 Mar; 10(1):35-42. Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. PMID: 14575156; PMCID: PMC2270675.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    74. The effect of house dust mite aeroallergen and air pollutant exposures during infancy. Chest. 2003 Mar; 123(3 Suppl):434S. Miller LA, Hyde DM, Gershwin LJ, Schelegle ES, Fanucchi MV, Evans MJ, Gerriets JE, Putney LF, Stovall MY, Tyler NK, Usachenko JL, Plopper CG. PMID: 12629026.
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    75. Repeated episodes of ozone inhalation attenuates airway injury/repair and release of substance P, but not adaptation. Toxicol Appl Pharmacol. 2003 Feb 01; 186(3):127-42. Schelegle ES, Walby WF, Alfaro MF, Wong VJ, Putney L, Stovall MY, Sterner-Kock A, Hyde DM, Plopper CG. PMID: 12620366.
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    76. Tethering tracheobronchial airways within the lungs. Am J Respir Crit Care Med. 2003 Jan 01; 167(1):2-3. Plopper CG, Nishio SJ, Schelegle ES. PMID: 12502468.
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    77. Functional morphology and physiology of slowly adapting pulmonary stretch receptors. Anat Rec A Discov Mol Cell Evol Biol. 2003 Jan; 270(1):11-6. Schelegle ES. PMID: 12494485.
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    78. Fibroblast growth factor-2 in remodeling of the developing basement membrane zone in the trachea of infant rhesus monkeys sensitized and challenged with allergen. Lab Invest. 2002 Dec; 82(12):1747-54. Evans MJ, Van Winkle LS, Fanucchi MV, Baker GL, Murphy AE, Nishio SJ, Schelegle ES, Gershwin LJ, Sannes PL, Plopper CG. PMID: 12480924.
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    79. Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats. J Appl Physiol (1985). 2001 Oct; 91(4):1611-8. Schelegle ES, Alfaro MF, Putney L, Stovall M, Tyler N, Hyde DM. PMID: 11568142.
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    80. Extended allergen exposure in asthmatic monkeys induces neuroplasticity in nucleus tractus solitarius. J Allergy Clin Immunol. 2001 Oct; 108(4):557-62. Chen CY, Bonham AC, Schelegle ES, Gershwin LJ, Plopper CG, Joad JP. PMID: 11590381.
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    81. Role of airway receptors in altitude-induced dyspnea. Med Sci Sports Exerc. 2001 Sep; 33(9):1449-55. Mansoor JK, Eldridge MW, Yoneda KY, Schelegle ES, Wood SC. PMID: 11528331.
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    82. Lung vagal afferent activity in rats with bleomycin-induced lung fibrosis. Respir Physiol. 2001 May; 126(1):9-27. Schelegle ES, Walby WF, Mansoor JK, Chen AT. PMID: 11311307.
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    83. Differential effects of airway anesthesia on ozone-induced pulmonary responses in human subjects. Am J Respir Crit Care Med. 2001 Apr; 163(5):1121-7. Schelegle ES, Eldridge MW, Cross CE, Walby WF, Adams WC. PMID: 11316647.
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    84. An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors. Respir Physiol. 2001 Mar; 125(1-2):17-31. Schelegle ES, Green JF. PMID: 11240150.
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    85. Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae). Am J Pathol. 2001 Jan; 158(1):333-41. Schelegle ES, Gershwin LJ, Miller LA, Fanucchi MV, Van Winkle LS, Gerriets JP, Walby WF, Omlor AM, Buckpitt AR, Tarkington BK, Wong VJ, Joad JP, Pinkerton KB, Wu R, Evans MJ, Hyde DM, Plopper CG. PMID: 11141508; PMCID: PMC1850255.
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    86. Three-dimensional mapping of ozone-induced acute cytotoxicity in tracheobronchial airways of isolated perfused rat lung. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):191-9. Postlethwait EM, Joad JP, Hyde DM, Schelegle ES, Bric JM, Weir AJ, Putney LF, Wong VJ, Velsor LW, Plopper CG. PMID: 10657940.
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    87. Interaction of vagal lung afferents with inhalation of histamine aerosol in anesthetized dogs. Lung. 2000; 178(1):41-52. Schelegle ES, Mansoor JK, Green JF. PMID: 10723719.
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    88. Effects of vagal perineural capsaicin treatment on vagal efferent and airway neurogenic responses in anesthetized rats. J Basic Clin Physiol Pharmacol. 2000; 11(1):1-16. Schelegle ES, Chen AT, Loh CY. PMID: 10851659.
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    89. Evaluation of severe disease induced by aerosol inoculation of calves with bovine respiratory syncytial virus. Am J Vet Res. 1999 Apr; 60(4):473-80. Woolums AR, Anderson ML, Gunther RA, Schelegle ES, LaRochelle DR, Singer RS, Boyle GA, Friebertshauser KE, Gershwin LJ. PMID: 10211692.
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    90. Breathing pattern response and epithelial labeling in ozone-induced airway injury in neutrophil-depleted rats. Am J Respir Cell Mol Biol. 1999 Apr; 20(4):699-709. Vesely KR, Schelegle ES, Stovall MY, Harkema JR, Green JF, Hyde DM. PMID: 10101002.
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    91. Effect of diet-ingested pirfenidone on pulmonary function, cardiovasculature and blood gas measurements in rats. Res Commun Mol Pathol Pharmacol. 1999 Mar; 103(3):260-8. Mansoor JK, Chen AT, Schelegle ES, Giri S. PMID: 10509737.
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    92. Capsaicin-sensitive C-fiber-mediated protective responses in ozone inhalation in rats. J Appl Physiol (1985). 1999 Mar; 86(3):951-62. Vesely KR, Hyde DM, Stovall MY, Harkema JR, Green JF, Schelegle ES. PMID: 10066710.
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    93. Control of ventilation during lung volume changes and permissive hypercapnia in dogs. Am J Respir Crit Care Med. 1998 Sep; 158(3):742-8. Carl ML, Schelegle ES, Hollstien SB, Green JF. PMID: 9730999.
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    94. A bovine model of vaccine enhanced respiratory syncytial virus pathophysiology. Vaccine. 1998 Jul; 16(11-12):1225-36. Gershwin LJ, Schelegle ES, Gunther RA, Anderson ML, Woolums AR, Larochelle DR, Boyle GA, Friebertshauser KE, Singer RS. PMID: 9682383.
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    95. Pirfenidone attenuates bleomycin-induced changes in pulmonary functions in hamsters. Proc Soc Exp Biol Med. 1997 Dec; 216(3):392-7. Schelegle ES, Mansoor JK, Giri S. PMID: 9402144.
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    96. Pulmonary vagal reflexes and breathing pattern are not altered in elastase-induced emphysema in rats. Exp Lung Res. 1997 Sep-Oct; 23(5):441-57. Mansoor JK, Hyde DM, Schelegie ES. PMID: 9267798.
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    97. Contribution of vagal afferents to breathing pattern in rats with lung fibrosis. Respir Physiol. 1997 Apr; 108(1):45-61. Mansoor JK, Hyde DM, Schelegle ES. PMID: 9178376.
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    98. Neonatal capsaicin treatment increases the severity of ozone-induced lung injury. Am J Respir Crit Care Med. 1996 Jan; 153(1):436-43. Sterner-Kock A, Vesely KR, Stovall MY, Schelegle ES, Green JF, Hyde DM. PMID: 8542155.
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    99. Influence of background vagal C-fiber activity on eupneic breathing pattern in anesthetized dogs. J Appl Physiol (1985). 1995 Aug; 79(2):600-6. Schelegle ES, Mansoor JK, Green JF. PMID: 7592224.
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    100. Pulmonary mechanics of dogs during transtracheal jet ventilation. Ann Emerg Med. 1994 Dec; 24(6):1126-36. Carl ML, Rhee KJ, Schelegle ES, Green JF. PMID: 7978595.
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    101. Effects of graded upper-airway obstruction on pulmonary mechanics during transtracheal jet ventilation in dogs. Ann Emerg Med. 1994 Dec; 24(6):1137-43. Carl ML, Rhee KJ, Schelegle ES, Green JF. PMID: 7978596.
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    102. Contribution of vagal afferents to respiratory reflexes evoked by acute inhalation of ozone in dogs. J Appl Physiol (1985). 1993 May; 74(5):2338-44. Schelegle ES, Carl ML, Coleridge HM, Coleridge JC, Green JF. PMID: 8335565.
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    103. Acute inhalation of ozone stimulates bronchial C-fibers and rapidly adapting receptors in dogs. J Appl Physiol (1985). 1993 May; 74(5):2345-52. Coleridge JC, Coleridge HM, Schelegle ES, Green JF. PMID: 8335566.
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    104. Corticosteroid administration modifies ozone-induced increases in sheep airway blood flow. Am Rev Respir Dis. 1992 Sep; 146(3):660-4. Gunther RA, Yousef MA, Schelegle ES, Cross CE. PMID: 1519844.
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    105. Role of vagal afferents in the control of abdominal expiratory muscle activity in the dog. J Appl Physiol (1985). 1991 Nov; 71(5):1795-800. Hollstien SB, Carl ML, Schelegle ES, Green JF. PMID: 1761476.
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    106. Time course of ozone-induced neutrophilia in normal humans. Am Rev Respir Dis. 1991 Jun; 143(6):1353-8. Schelegle ES, Siefkin AD, McDonald RJ. PMID: 2048824.
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    107. Acute ozone exposure increases bronchial blood flow in conscious sheep. Respir Physiol. 1990 Dec; 82(3):325-35. Schelegle ES, Gunther RA, Parsons GH, Colbert SR, Yousef MA, Cross CE. PMID: 2080322.
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    108. Ozone-induced accelerated lung clearance of 99mTc-DTPA aerosol in conscious sheep. Respir Physiol. 1989 Sep; 77(3):277-90. Hornof WJ, Schelegle E, Kammerman M, Gunther RA, Fisher PE, Cross CE. PMID: 2506622.
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    109. Oral and oronasal breathing during continuous exercise produce similar responses to ozone inhalation. Arch Environ Health. 1989 Sep-Oct; 44(5):311-6. Adams WC, Schelegle ES, Shaffrath JD. PMID: 2817961.
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    110. Acute ozone exposure increases plasma prostaglandin F2 alpha in ozone-sensitive human subjects. Am Rev Respir Dis. 1989 Jul; 140(1):211-6. Schelegle ES, Adams WC, Giri SN, Siefkin AD. PMID: 2751167.
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    111. Duration of enhanced responsiveness upon re-exposure to ozone. Arch Environ Health. 1989 Jul-Aug; 44(4):229-36. Schonfeld BR, Adams WC, Schelegle ES. PMID: 2782945.
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    112. O.35 ppm O3 exposure induces hyperresponsiveness on 24-h reexposure to 0.20 ppm O3. J Appl Physiol (1985). 1989 Jun; 66(6):2756-62. Brookes KA, Adams WC, Schelegle ES. PMID: 2745339.
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    113. Indomethacin pretreatment reduces ozone-induced pulmonary function decrements in human subjects. Am Rev Respir Dis. 1987 Dec; 136(6):1350-4. Schelegle ES, Adams WC, Siefkin AD. PMID: 3688637.
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    114. Effects of NO2 alone and in combination with O3 on young men and women. J Appl Physiol (1985). 1987 Apr; 62(4):1698-704. Adams WC, Brookes KA, Schelegle ES. PMID: 3597241.
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    115. Reduced exercise time in competitive simulations consequent to low level ozone exposure. Med Sci Sports Exerc. 1986 Aug; 18(4):408-14. Schelegle ES, Adams WC. PMID: 3747800.
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    116. Ozone and high ventilation effects on pulmonary function and endurance performance. J Appl Physiol Respir Environ Exerc Physiol. 1983 Sep; 55(3):805-12. Adams WC, Schelegle ES. PMID: 6629918.
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