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Richart W Harper

Title(s)Professor, Pulmonary, Critical Care, and Sleep Medicine
SchoolUniversity of California, Davis
Phone916-734-3564
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. McCartney MM, Yamaguchi MS, Bowles PA, Gratch YS, Iyer RK, Linderholm AL, Ebeler SE, Kenyon NJ, Schivo M, Harper RW, Goodwin P, Davis CE. Volatile organic compound (VOC) emissions of CHO and T cells correlate to their expansion in bioreactors. J Breath Res. 2019 Oct 21; 14(1):016002. PMID: 31430743.
      View in: PubMed
    2. Albertson TE, Bowman WS, Harper RW, Godbout RM, Murin S. Evidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2019; 14:1251-1265. PMID: 31239659.
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    3. Zhu L, An L, Ran D, Lizarraga R, Bondy C, Zhou X, Harper RW, Liao SY, Chen Y. The Club Cell Marker SCGB1A1 Downstream of FOXA2 is Reduced in Asthma. Am J Respir Cell Mol Biol. 2019 Jun; 60(6):695-704. PMID: 30576223.
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    4. Liao SY, Linderholm AL, Yoneda KY, Kenyon NJ, Harper RW. Airway transcriptomic profiling after bronchial thermoplasty. ERJ Open Res. 2019 Feb; 5(1). PMID: 30792984.
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    5. Pugashetti J, Graham J, Boctor N, Mendez C, Foster E, Juarez M, Harper R, Morrissey B, Kadoch M, Oldham JM. Weight loss as a predictor of mortality in patients with interstitial lung disease. Eur Respir J. 2018 09; 52(3). PMID: 30072505.
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    6. Solbes E, Harper RW. Biological responses to asbestos inhalation and pathogenesis of asbestos-related benign and malignant disease. J Investig Med. 2018 04; 66(4):721-727. PMID: 29306869.
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    7. Cagle LA, Franzi LM, Linderholm AL, Last JA, Adams JY, Harper RW, Kenyon NJ. Effects of positive end-expiratory pressure and recruitment maneuvers in a ventilator-induced injury mouse model. PLoS One. 2017; 12(11):e0187419. PMID: 29112971.
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    8. Harper RW. Partners in Crime: Epithelial Priming of Macrophages during Viral Infection. Am J Respir Cell Mol Biol. 2017 08; 57(2):145-146. PMID: 28762773.
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    9. Black C, Gerriets JE, Fontaine JH, Harper RW, Kenyon NJ, Tablin F, Schelegle ES, Miller LA. Early Life Wildfire Smoke Exposure Is Associated with Immune Dysregulation and Lung Function Decrements in Adolescence. Am J Respir Cell Mol Biol. 2017 05; 56(5):657-666. PMID: 28208028.
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    10. Chang S, Linderholm A, Harper R. DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways. PLoS One. 2015; 10(7):e0131810. PMID: 26148206.
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    11. Schivo M, Phan C, Louie S, Harper RW. Critical asthma syndrome in the ICU. Clin Rev Allergy Immunol. 2015 Feb; 48(1):31-44. PMID: 25759905.
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    12. Harper RW, Zeki AA. Immunobiology of the critical asthma syndrome. Clin Rev Allergy Immunol. 2015 Feb; 48(1):54-65. PMID: 24399247.
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    13. Schivo M, Aksenov AA, Linderholm AL, McCartney MM, Simmons J, Harper RW, Davis CE. Volatile emanations from in vitro airway cells infected with human rhinovirus. J Breath Res. 2014 Sep; 8(3):037110. PMID: 25189196.
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    14. Aksenov AA, Sandrock CE, Zhao W, Sankaran S, Schivo M, Harper R, Cardona CJ, Xing Z, Davis CE. Cellular scent of influenza virus infection. Chembiochem. 2014 May 05; 15(7):1040-8. PMID: 24719290.
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    15. MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A. DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid. Inflamm Bowel Dis. 2014 Mar; 20(3):514-24. PMID: 24492313.
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    16. Schivo M, Phan C, Louie S, Harper RW. Critical Asthma Syndrome in the ICU. Clin Rev Allergy Immunol. 2013 Nov 15. PMID: 24234835.
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    17. Chang S, Linderholm A, Franzi L, Kenyon N, Grasberger H, Harper R. Dual oxidase regulates neutrophil recruitment in allergic airways. Free Radic Biol Med. 2013 Dec; 65:38-46. PMID: 23770197.
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    18. Price D, Harper R, Henderson MC. Progressive cervical myelopathy as presentation of sarcoidosis. J Gen Intern Med. 2013 Jun; 28(6):855-6. PMID: 23371382.
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    19. Di YP, Zhao J, Harper R. Cigarette smoke induces MUC5AC protein expression through the activation of Sp1. J Biol Chem. 2012 Aug 10; 287(33):27948-58. PMID: 22700966.
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    20. Xu C, Linderholm A, Grasberger H, Harper RW. Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia. Am J Respir Cell Mol Biol. 2012 Oct; 47(4):484-90. PMID: 22592922.
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    21. Linderholm AL, Onitsuka J, Xu C, Chiu M, Lee WM, Harper RW. All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium. Am J Physiol Lung Cell Mol Physiol. 2010 Aug; 299(2):L215-21. PMID: 20511343.
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    22. Hill T, Xu C, Harper RW. IFNgamma mediates DUOX2 expression via a STAT-independent signaling pathway. Biochem Biophys Res Commun. 2010 Apr 30; 395(2):270-4. PMID: 20381453.
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    23. Xing Z, Harper R, Anunciacion J, Yang Z, Gao W, Qu B, Guan Y, Cardona CJ. Host immune and apoptotic responses to avian influenza virus H9N2 in human tracheobronchial epithelial cells. Am J Respir Cell Mol Biol. 2011 Jan; 44(1):24-33. PMID: 20118223.
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    24. Stollenwerk N, Harper RW, Sandrock CE. Bench-to-bedside review: rare and common viral infections in the intensive care unit--linking pathophysiology to clinical presentation. Crit Care. 2008; 12(4):219. PMID: 18671826.
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    25. Lee YC, Chuang CY, Lee PK, Lee JS, Harper RW, Buckpitt AB, Wu R, Oslund K. TRX-ASK1-JNK signaling regulation of cell density-dependent cytotoxicity in cigarette smoke-exposed human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5):L921-31. PMID: 18281606.
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    26. Zhao J, Harper R, Barchowsky A, Di YP. Identification of multiple MAPK-mediated transcription factors regulated by tobacco smoke in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2007 Aug; 293(2):L480-90. PMID: 17496060.
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    27. Phung AD, Soucek K, Kubala L, Harper RW, Chloƫ Bulinski J, Eiserich JP. Posttranslational nitrotyrosination of alpha-tubulin induces cell cycle arrest and inhibits proliferation of vascular smooth muscle cells. Eur J Cell Biol. 2006 Dec; 85(12):1241-52. PMID: 17118269.
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    28. Harper RW, Xu C, McManus M, Heidersbach A, Eiserich JP. Duox2 exhibits potent heme peroxidase activity in human respiratory tract epithelium. FEBS Lett. 2006 Oct 02; 580(22):5150-4. PMID: 16970942.
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    29. Soucek K, Kamaid A, Phung AD, Kubala L, Bulinski JC, Harper RW, Eiserich JP. Normal and prostate cancer cells display distinct molecular profiles of alpha-tubulin posttranslational modifications. Prostate. 2006 Jun 15; 66(9):954-65. PMID: 16541425.
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    30. Black H, Sigal D, Barnes D, Felisky C, Follette D, Harper R. A 25-year-old patient with spontaneous hemothorax. Chest. 2005 Oct; 128(4):3080-1, 3082-3. PMID: 16236990.
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    31. Harper RW, Xu C, Eiserich JP, Chen Y, Kao CY, Thai P, Setiadi H, Wu R. Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Lett. 2005 Aug 29; 579(21):4911-7. PMID: 16111680.
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    32. Harper RW, Xu C, Soucek K, Setiadi H, Eiserich JP. A reappraisal of the genomic organization of human Nox1 and its splice variants. Arch Biochem Biophys. 2005 Mar 15; 435(2):323-30. PMID: 15708375.
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    33. Harper R, Xu C, Di P, Chen Y, Privalsky M, Wu R. Identification of a novel MAGE D2 antisense RNA transcript in human tissues. Biochem Biophys Res Commun. 2004 Nov 05; 324(1):199-204. PMID: 15465002.
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    34. Bair AE, Doherty MJ, Harper R, Albertson TE. An evaluation of a blind rotational technique for selective mainstem intubation. Acad Emerg Med. 2004 Oct; 11(10):1105-7. PMID: 15466157.
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    35. Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004 Sep 01; 173(5):3482-91. PMID: 15322213.
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    36. Morrissey BM, Harper RW. Bronchiectasis: sex and gender considerations. Clin Chest Med. 2004 Jun; 25(2):361-72. PMID: 15099895.
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    37. Yoneda KY, Harper RW, Louie S. Severe chronic obstructive pulmonary disease. Clin Rev Allergy Immunol. 2003 Oct; 25(2):151-63. PMID: 14573882.
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    38. Di YP, Harper R, Zhao Y, Pahlavan N, Finkbeiner W, Wu R. Molecular cloning and characterization of spurt, a human novel gene that is retinoic acid-inducible and encodes a secretory protein specific in upper respiratory tracts. J Biol Chem. 2003 Jan 10; 278(2):1165-73. PMID: 12409287.
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    39. Chang WH, Reddy SP, Di YP, Yoneda K, Harper R, Wu R. Regulation of thioredoxin gene expression by vitamin A in human airway epithelial cells. Am J Respir Cell Mol Biol. 2002 May; 26(5):627-35. PMID: 11970916.
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    40. Harper R, Wu K, Chang MM, Yoneda K, Pan R, Reddy SP, Wu R. Activation of nuclear factor-kappa b transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and glutathione. Am J Respir Cell Mol Biol. 2001 Aug; 25(2):178-85. PMID: 11509327.
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    41. Chang MM, Harper R, Hyde DM, Wu R. A novel mechanism of retinoic acid-enhanced interleukin-8 gene expression in airway epithelium. Am J Respir Cell Mol Biol. 2000 Apr; 22(4):502-10. PMID: 10745031.
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    42. Gianlupi A, Harper RW, Dwyre DM, Marelich GP. Recurrent pulmonary embolism associated with Klippel-Trenaunay-Weber syndrome. Chest. 1999 Apr; 115(4):1199-201. PMID: 10208231.
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