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Laurel Gershwin

TitleAssociate Professor
InstitutionUniversity of California Davis
DepartmentPathology, Microbiology and Immunology
Address3327 Vet Med 3A
CA 95616
Phone530-752-6643
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gershwin LJ. Current and Newly Emerging Autoimmune Diseases. Vet Clin North Am Small Anim Pract. 2018 Mar; 48(2):323-338. PMID: 29248206.
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    2. Gershwin LJ. Adverse Reactions to Vaccination: From Anaphylaxis to Autoimmunity. Vet Clin North Am Small Anim Pract. 2018 Mar; 48(2):279-290. PMID: 29195924.
      View in: PubMed
    3. Gershwin LJ, Behrens NE, McEligot HA, Carvallo-Chaigneau FR, Crum LT, Gunnarson BM, Corbeil LB. A recombinant subunit vaccine for bovine RSV and Histophilus somni protects calves against dual pathogen challenge. Vaccine. 2017 04 04; 35(15):1954-1963. PMID: 28274639.
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    4. Walsh P, Behrens N, Carvallo Chaigneau FR, McEligot H, Agrawal K, Newman JW, Anderson M, Gershwin LJ. A Randomized Placebo Controlled Trial of Ibuprofen for Respiratory Syncytial Virus Infection in a Bovine Model. PLoS One. 2016; 11(4):e0152913. PMID: 27073858; PMCID: PMC4830518.
    5. Gershwin LJ, Van Eenennaam AL, Anderson ML, McEligot HA, Shao MX, Toaff-Rosenstein R, Taylor JF, Neibergs HL, Womack J. Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex. PLoS One. 2015; 10(11):e0142479. PMID: 26571015; PMCID: PMC4646450.
    6. Behrens NE, Gershwin LJ. Immune modulation of T regulatory cells and IgE responses in horses vaccinated with West Nile virus vaccine combined with a CpG ODN. Vaccine. 2015 Oct 26; 33(43):5764-5771. PMID: 26424604.
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    7. Tizioto PC, Kim J, Seabury CM, Schnabel RD, Gershwin LJ, Van Eenennaam AL, Toaff-Rosenstein R, Neibergs HL, Taylor JF. Immunological Response to Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex: An RNA-Sequence Analysis of the Bronchial Lymph Node Transcriptome. PLoS One. 2015; 10(6):e0131459. PMID: 26121276; PMCID: PMC4484807.
    8. Jordan R, Shao M, Mackman RL, Perron M, Cihlar T, Lewis SA, Eisenberg EJ, Carey A, Strickley RG, Chien JW, Anderson ML, McEligot HA, Behrens NE, Gershwin LJ. Antiviral Efficacy of a Respiratory Syncytial Virus (RSV) Fusion Inhibitor in a Bovine Model of RSV Infection. Antimicrob Agents Chemother. 2015 Aug; 59(8):4889-900. PMID: 26055364; PMCID: PMC4505261.
    9. Gershwin LJ. Comparative immunology of allergic responses. Annu Rev Anim Biosci. 2015; 3:327-46. PMID: 25422854.
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    10. Wai CY, Leung NY, Ho MH, Gershwin LJ, Shu SA, Leung PS, Chu KH. Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. PLoS One. 2014; 9(11):e111649. PMID: 25365343; PMCID: PMC4218792.
    11. Borchers AT, Chang C, Gershwin ME, Gershwin LJ. Respiratory syncytial virus--a comprehensive review. Clin Rev Allergy Immunol. 2013 Dec; 45(3):331-79. PMID: 23575961.
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    12. Venema CM, Williams KJ, Gershwin LJ, Reinero CR, Carey SA. Histopathologic and morphometric evaluation of the nasal and pulmonary airways of cats with experimentally induced asthma. Int Arch Allergy Immunol. 2013; 160(4):365-76. PMID: 23183217.
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    13. Gershwin LJ, Netherwood KA, Norris MS, Behrens NE, Shao MX. Equine IgE responses to non-viral vaccine components. Vaccine. 2012 Dec 14; 30(52):7615-20. PMID: 23088888.
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    14. Mitchell VL, Van Winkle LS, Gershwin LJ. Environmental tobacco smoke and progesterone alter lung inflammation and mucous metaplasia in a mouse model of allergic airway disease. Clin Rev Allergy Immunol. 2012 Aug; 43(1-2):57-68. PMID: 21837398.
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    15. Lo KL, Kimball RA, Lehmann J, Gershwin LJ, Worby C, Corbeil LB. Antibody responses of calves to Histophilus somni recombinant IbpA subunits. Comp Immunol Microbiol Infect Dis. 2012 Sep; 35(5):453-9. PMID: 22554920.
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    16. Gershwin LJ. Immunology of bovine respiratory syncytial virus infection of cattle. Comp Immunol Microbiol Infect Dis. 2012 May; 35(3):253-7. PMID: 22410266.
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    17. Gershwin LJ, Anderson ML, Wang C, Berghaus LJ, Kenny TP, Gunther RA. Assessment of IgE response and cytokine gene expression in pulmonary efferent lymph collected after ovalbumin inhalation during experimental infection of calves with bovine respiratory syncytial virus. Am J Vet Res. 2011 Jan; 72(1):134-45. PMID: 21194346.
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    18. Sitt T, Bowen L, Blanchard MT, Gershwin LJ, Byrne BA, Dold C, McBain J, Stott JL. Cellular immune responses in cetaceans immunized with a porcine erysipelas vaccine. Vet Immunol Immunopathol. 2010 Oct 15; 137(3-4):181-9. PMID: 20579745.
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    19. Gershwin LJ. Autoimmune diseases in small animals. Vet Clin North Am Small Anim Pract. 2010 May; 40(3):439-57. PMID: 20471527.
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    20. Comstock SS, Gershwin LJ, Teuber SS. Effect of walnut (Juglans regia) polyphenolic compounds on ovalbumin-specific IgE induction in female BALB/c mice. Ann N Y Acad Sci. 2010 Mar; 1190:58-69. PMID: 20388137.
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    21. Cobo ER, Corbeil LB, Gershwin LJ, BonDurant RH. Preputial cellular and antibody responses of bulls vaccinated and/or challenged with Tritrichomonas foetus. Vaccine. 2009 Dec 11; 28(2):361-70. PMID: 19879225.
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    22. Gershwin LJ. Immunoglobulin E and allergy in domestic animals. Foreword. Vet Immunol Immunopathol. 2009 Nov 15; 132(1):1. PMID: 19836082.
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    23. Gershwin LJ. Bovine immunoglobulin E. Vet Immunol Immunopathol. 2009 Nov 15; 132(1):2-6. PMID: 19819026.
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    24. Sitt T, Bowen L, Blanchard MT, Smith BR, Gershwin LJ, Byrne BA, Stott JL. Quantitation of leukocyte gene expression in cetaceans. Dev Comp Immunol. 2008; 32(11):1253-9. PMID: 18572242.
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    25. Gershwin LJ, Gunther RA, Hornof WJ, Larson RF. Effect of infection with bovine respiratory syncytial virus on pulmonary clearance of an inhaled antigen in calves. Am J Vet Res. 2008 Mar; 69(3):416-22. PMID: 18312142.
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    26. Gershwin LJ. Bovine respiratory syncytial virus infection: immunopathogenic mechanisms. Anim Health Res Rev. 2007 Dec; 8(2):207-13. PMID: 18218161.
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    27. Joad JP, Kott KS, Bric JM, Schelegle ES, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE. The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone. Toxicol Appl Pharmacol. 2008 Jan 15; 226(2):153-60. PMID: 17991502.
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    28. Gershwin LJ. Effects of allergenic extracts on airway epithelium. Curr Allergy Asthma Rep. 2007 Sep; 7(5):357-62. PMID: 17697644.
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    29. Gershwin LJ. Veterinary autoimmunity: autoimmune diseases in domestic animals. Ann N Y Acad Sci. 2007 Aug; 1109:109-16. PMID: 17785296.
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    30. Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM. Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology? Toxicol Pathol. 2007 Jan; 35(1):97-110. PMID: 17325978.
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    31. Avdalovic MV, Putney LF, Schelegle ES, Miller L, Usachenko JL, Tyler NK, Plopper CG, Gershwin LJ, Hyde DM. Vascular remodeling is airway generation-specific in a primate model of chronic asthma. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1069-76. PMID: 16931639; PMCID: PMC2648107.
    32. Corbeil LB, Arnold KF, Kimball R, Berghaus L, Gershwin LJ. Specificity of IgG and IgE antibody responses to Haemophilus somnus infection of calves. Vet Immunol Immunopathol. 2006 Sep 15; 113(1-2):191-9. PMID: 16824620.
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    33. Fanucchi MV, Plopper CG, Evans MJ, Hyde DM, Van Winkle LS, Gershwin LJ, Schelegle ES. Cyclic exposure to ozone alters distal airway development in infant rhesus monkeys. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L644-50. PMID: 16648242.
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    34. Berghaus LJ, Corbeil LB, Berghaus RD, Kalina WV, Kimball RA, Gershwin LJ. Effects of dual vaccination for bovine respiratory syncytial virus and Haemophilus somnus on immune responses. Vaccine. 2006 Aug 14; 24(33-34):6018-27. PMID: 16777273.
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    35. Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle ES, Gershwin LJ, Pinkerton KE. Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone. Toxicol Appl Pharmacol. 2006 Aug 01; 214(3):237-43. PMID: 16466656.
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    36. Reinero CR, Brownlee L, Decile KC, Seguin B, Berghaus RD, Nelson RW, Gershwin LJ. Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats. J Vet Intern Med. 2006 Jan-Feb; 20(1):57-64. PMID: 16496924.
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    37. Reinero CR, Byerly JR, Berghaus RD, Berghaus LJ, Schelegle ES, Hyde DM, Gershwin LJ. Rush immunotherapy in an experimental model of feline allergic asthma. Vet Immunol Immunopathol. 2006 Mar 15; 110(1-2):141-53. PMID: 16325921.
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    38. Kalina WV, Woolums AR, Gershwin LJ. Formalin-inactivated bovine RSV vaccine influences antibody levels in bronchoalveolar lavage fluid and disease outcome in experimentally infected calves. Vaccine. 2005 Aug 31; 23(37):4625-30. PMID: 15967545.
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    39. Gershwin LJ, Berghaus LJ, Arnold K, Anderson ML, Corbeil LB. Immune mechanisms of pathogenetic synergy in concurrent bovine pulmonary infection with Haemophilus somnus and bovine respiratory syncytial virus. Vet Immunol Immunopathol. 2005 Aug 15; 107(1-2):119-30. PMID: 15979157.
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    40. Reinero CR, Decile KC, Byerly JR, Berghaus RD, Walby WE, Berghaus LJ, Hyde DM, Schelegle ES, Gershwin LJ. Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma. Am J Vet Res. 2005 Jul; 66(7):1121-7. PMID: 16111148.
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    41. Seymour BW, Peake JL, Pinkerton KE, Kurup VP, Gershwin LJ. Second-hand smoke increases nitric oxide and alters the IgE response in a murine model of allergic aspergillosis. Clin Dev Immunol. 2005 Jun; 12(2):113-24. PMID: 16050142; PMCID: PMC2270730.
    42. Gershwin LJ. Antinuclear antibodies in domestic animals. Ann N Y Acad Sci. 2005 Jun; 1050:364-70. PMID: 16014553.
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    43. Kashino SS, Resende J, Sacco AM, Rocha C, Proença L, Carvalho WA, Firmino AA, Queiroz R, Benavides M, Gershwin LJ, De Miranda Santos IK. Boophilus microplus: the pattern of bovine immunoglobulin isotype responses to high and low tick infestations. Exp Parasitol. 2005 May; 110(1):12-21. PMID: 15804374.
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    44. Vaughan K, Rhodes GH, Gershwin LJ. DNA immunization against respiratory syncytial virus (RSV) in infant rhesus monkeys. Vaccine. 2005 Apr 22; 23(22):2928-42. PMID: 15780742.
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    45. Chou DL, Daugherty BL, McKenna EK, Hsu WM, Tyler NK, Plopper CG, Hyde DM, Schelegle ES, Gershwin LJ, Miller LA. Chronic aeroallergen during infancy enhances eotaxin-3 expression in airway epithelium and nerves. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):1-8. PMID: 15834047; PMCID: PMC2715301.
    46. Tran MU, Weir AJ, Fanucchi MV, Murphy AE, Van Winkle LS, Evans MJ, Smiley-Jewell SM, Miller L, Schelegle ES, Gershwin LJ, Hyde DM, Plopper CG. Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys. J Appl Physiol (1985). 2004 Dec; 97(6):2364-71; discussion 2354. PMID: 15347627.
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    47. Norris Reinero CR, Decile KC, Berghaus RD, Williams KJ, Leutenegger CM, Walby WF, Schelegle ES, Hyde DM, Gershwin LJ. An experimental model of allergic asthma in cats sensitized to house dust mite or bermuda grass allergen. Int Arch Allergy Immunol. 2004 Oct; 135(2):117-31. PMID: 15345910.
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    48. Fanucchi MV, Schelegle ES, Baker GL, Evans MJ, McDonald RJ, Gershwin LJ, Raz E, Hyde DM, Plopper CG, Miller LA. Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys. Am J Respir Crit Care Med. 2004 Dec 01; 170(11):1153-7. PMID: 15306532; PMCID: PMC3927836.
    49. Van Winkle LS, Fanucchi MV, Miller LA, Baker GL, Gershwin LJ, Schelegle ES, Hyde DM, Evans MJ, Plopper CG. Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development. J Appl Physiol (1985). 2004 Dec; 97(6):2355-63; discussion 2354. PMID: 15298983.
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    50. Kalina WV, Woolums AR, Berghaus RD, Gershwin LJ. Formalin-inactivated bovine RSV vaccine enhances a Th2 mediated immune response in infected cattle. Vaccine. 2004 Mar 29; 22(11-12):1465-74. PMID: 15063570.
      View in: PubMed
    51. Woolums AR, Gunther RA, McArthur-Vaughan K, Anderson ML, Omlor A, Boyle GA, Friebertshauser KE, McInturff PS, Gershwin LJ. Cytotoxic T lymphocyte activity and cytokine expression in calves vaccinated with formalin-inactivated bovine respiratory syncytial virus prior to challenge. Comp Immunol Microbiol Infect Dis. 2004 Jan; 27(1):57-74. PMID: 14656542.
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    52. Norris CR, Decile KC, Berghaus LJ, Berghaus RD, Walby WF, Schelegle ES, Hyde DM, Gershwin LJ. Concentrations of cysteinyl leukotrienes in urine and bronchoalveolar lavage fluid of cats with experimentally induced asthma. Am J Vet Res. 2003 Nov; 64(11):1449-53. PMID: 14620784.
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    53. Schelegle ES, Miller LA, Gershwin LJ, Fanucchi MV, Van Winkle LS, Gerriets JE, Walby WF, Mitchell V, Tarkington BK, Wong VJ, Baker GL, Pantle LM, Joad JP, Pinkerton KE, Wu R, Evans MJ, Hyde DM, Plopper CG. Repeated episodes of ozone inhalation amplifies the effects of allergen sensitization and inhalation on airway immune and structural development in Rhesus monkeys. Toxicol Appl Pharmacol. 2003 Aug 15; 191(1):74-85. PMID: 12915105.
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    54. Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle ES, Gershwin LJ, Miller LA, Hyde DM, Sannes PL, Plopper CG. Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L931-9. PMID: 12832283.
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    55. Gershwin LJ. Effects of air pollutants on development of allergic immune responses in the respiratory tract. Clin Dev Immunol. 2003 Jun-Dec; 10(2-4):119-26. PMID: 14768942; PMCID: PMC2485425.
    56. Kalina WV, Pettigrew HD, Gershwin LJ. IgE ELISA using antisera derived from epsilon chain antigenic peptides detects allergen-specific IgE in allergic horses. Vet Immunol Immunopathol. 2003 May 12; 92(3-4):137-47. PMID: 12730014.
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    57. Norris CR, Gershwin LJ. Evaluation of systemic and secretory IgA concentrations and immunohistochemical stains for IgA-containing B cells in mucosal tissues of an Irish setter with selective IgA deficiency. J Am Anim Hosp Assoc. 2003 May-Jun; 39(3):247-50. PMID: 12755197.
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    58. Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, Coffman RL, Gershwin LJ. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol. 2003 Mar; 10(1):35-42. PMID: 14575156; PMCID: PMC2270675.
    59. Miller LA, Hyde DM, Gershwin LJ, Schelegle ES, Fanucchi MV, Evans MJ, Gerriets JE, Putney LF, Stovall MY, Tyler NK, Usachenko JL, Plopper CG. The effect of house dust mite aeroallergen and air pollutant exposures during infancy. Chest. 2003 Mar; 123(3 Suppl):434S. PMID: 12629026.
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    60. Schmidt U, Beyer J, Polster U, Gershwin LJ, Buchholz UJ. Mucosal immunization with live recombinant bovine respiratory syncytial virus (BRSV) and recombinant BRSV lacking the envelope glycoprotein G protects against challenge with wild-type BRSV. J Virol. 2002 Dec; 76(23):12355-9. PMID: 12414977; PMCID: PMC136874.
    61. Evans MJ, Van Winkle LS, Fanucchi MV, Baker GL, Murphy AE, Nishio SJ, Schelegle ES, Gershwin LJ, Sannes PL, Plopper CG. Fibroblast growth factor-2 in remodeling of the developing basement membrane zone in the trachea of infant rhesus monkeys sensitized and challenged with allergen. Lab Invest. 2002 Dec; 82(12):1747-54. PMID: 12480924.
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    62. Seymour BW, Friebertshauser KE, Peake JL, Pinkerton KE, Coffman RL, Gershwin LJ. Gender differences in the allergic response of mice neonatally exposed to environmental tobacco smoke. Dev Immunol. 2002 Mar; 9(1):47-54. PMID: 12353662; PMCID: PMC2276086.
    63. Gershwin LJ. Immunoglobulin E-mediated hypersensitivity in food-producing animals. Vet Clin North Am Food Anim Pract. 2001 Nov; 17(3):599-619. PMID: 11692511.
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    64. Gershwin LJ, Schelegle ES, Gunther RA, Anderson ML, Woolums AR, Larochelle DR, Boyle GA, Friebertshauser KE, Singer RS. A bovine model of vaccine enhanced respiratory syncytial virus pathophysiology. Vaccine. 1998 Jul; 16(11-12):1225-36. PMID: 9682383.
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