Loading...

Paul Albert Sieving

Title(s)Professor, Ophthalmology
SchoolUniversity of California, Davis
Address
Phone301-496-2234
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    JUVENILE RETINOSCHISIS
    NIH/NEI R01EY010259Sep 30, 1993 - Sep 29, 1996
    Role: Principal Investigator
    INNER RETINAL CONTRIBUTIONS TO THE ERG
    NIH/NEI R01EY006094May 1, 1986 - Nov 30, 2005
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genetic rescue of X-linked retinoschisis mouse (Rs1-/y) retina induces quiescence of the retinal microglial inflammatory state following AAV8-RS1 gene transfer and identifies gene networks underlying retinal recovery. Hum Gene Ther. 2020 Oct 06. Vijayasarathy C, Zeng Y, Brooks M, Fariss RN, Sieving PA. PMID: 33019822.
      View in: PubMed   Mentions:    Fields:    
    2. NEI-Supported Age-Related Macular Degeneration Research: Past, Present, and Future. Transl Vis Sci Technol. 2020 Jun; 9(7):49. Wright C, Mazzucco AE, Becker SM, Sieving PA, Tumminia SJ. PMID: 32832254.
      View in: PubMed   Mentions:
    3. Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration. Transl Vis Sci Technol. 2020 Jun; 9(7):28. Song H, Zeng Y, Sardar Pasha SPB, Bush RA, Vijayasarathy C, Qian H, Wei L, Wiley HE, Wu Z, Sieving PA. PMID: 32844051.
      View in: PubMed   Mentions:
    4. "Para-retinal" Vector Administration into the Deep Vitreous Enhances Retinal Transgene Expression. Mol Ther Methods Clin Dev. 2020 Sep 11; 18:422-427. Zeng Y, Boyd R, Bartoe J, Wiley HE, Marangoni D, Wei LL, Sieving PA. PMID: 32695844.
      View in: PubMed   Mentions:
    5. Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium. Transl Vis Sci Technol. 2020 Jun; 9(7):2. Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, Gattegna R, Heckenlively JR, Heon E, Jayasundera KT, Khan NW, Klassen H, Leroy BP, Molday RS, Musch DC, Pennesi ME, Petersen-Jones SM, Pierce EA, Rao RC, Reh TA, Sahel JA, Sharon D, Sieving PA, Strettoi E, Yang P, Zacks DN. PMID: 32832209.
      View in: PubMed   Mentions:
    6. "There Are Hills and Valleys": Experiences of Parenting a Son With X-Linked Retinoschisis. Am J Ophthalmol. 2020 04; 212:98-104. Turriff A, Nolen R, D'Amanda C, Biesecker B, Cukras C, Sieving PA. PMID: 31765628.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Cone ERG Changes During Light Adaptation in Two All-Cone Mutant Mice: Implications for Rod-Cone Pathway Interactions. Invest Ophthalmol Vis Sci. 2019 08 01; 60(10):3680-3688. Bush RA, Tanikawa A, Zeng Y, Sieving PA. PMID: 31469895.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration. Gene Ther. 2019 09; 26(9):386-398. Zeng Y, Qian H, Wu Z, Marangoni D, Sieving PA, Bush RA. PMID: 31308478.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    9. Improved Ocular Tissue Models and Eye-On-A-Chip Technologies Will Facilitate Ophthalmic Drug Development. J Ocul Pharmacol Ther. 2020 Jan/Feb; 36(1):25-29. Wright CB, Becker SM, Low LA, Tagle DA, Sieving PA. PMID: 31166829.
      View in: PubMed   Mentions: 1     Fields:    
    10. Motivations and Decision Making Processes of Men With X-linked Retinoschisis Considering Participation in an Ocular Gene Therapy Trial. Am J Ophthalmol. 2019 08; 204:90-96. Turriff A, Blain D, Similuk M, Biesecker B, Wiley H, Cukras C, Sieving PA. PMID: 30885710.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    11. The NIH Blueprint for Neuroscience Research Seeks Community Input on Future Neuroscience Investments. J Neurosci. 2019 01 30; 39(5):774-775. Mott MC, Austin CP, Bianchi DW, Cashion AK, Gordon JA, Heemskerk JE, Hodes RJ, Koob GF, Riley WT, Sieving PA, Shurtleff D, Somerman MJ, Volkow ND, Anderson KC, Owens DF, Koroshetz WJ. PMID: 30700523.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina. J Cell Biol. 2019 03 04; 218(3):1027-1038. Heymann JB, Vijayasarathy C, Huang RK, Dearborn AD, Sieving PA, Steven AC. PMID: 30630865.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. Trans-ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Gene Transduction after Intravitreal Vector Administration. Mol Ther Methods Clin Dev. 2019 Jun 14; 13:77-85. Song H, Bush RA, Zeng Y, Qian H, Wu Z, Sieving PA. PMID: 30719486.
      View in: PubMed   Mentions:
    14. Neuroethics for the National Institutes of Health BRAIN Initiative. J Neurosci. 2018 12 12; 38(50):10583-10585. Bianchi DW, Cooper JA, Gordon JA, Heemskerk J, Hodes R, Koob GF, Koroshetz WJ, Shurtleff D, Sieving PA, Volkow ND, Churchill JD, Ramos KM. PMID: 30541766.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. The National Eye Institute's Commitment to Career Development of Clinician-Scientists. JAMA Ophthalmol. 2018 12 01; 136(12):1340-1341. Agarwal N, Steinmetz MA, Sieving P. PMID: 30267051.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy. J Clin Invest. 2018 12 03; 128(12):5663-5675. Burkard M, Kohl S, Krätzig T, Tanimoto N, Brennenstuhl C, Bausch AE, Junger K, Reuter P, Sothilingam V, Beck SC, Huber G, Ding XQ, Mayer AK, Baumann B, Weisschuh N, Zobor D, Hahn GA, Kellner U, Venturelli S, Becirovic E, Charbel Issa P, Koenekoop RK, Rudolph G, Heckenlively J, Sieving P, Weleber RG, Hamel C, Zong X, Biel M, Lukowski R, Seeliger MW, Michalakis S, Wissinger B, Ruth P. PMID: 30418171.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    17. Translational Retinal Research and Therapies. Transl Vis Sci Technol. 2018 Sep; 7(5):8. Hardcastle AJ, Sieving PA, Sahel JA, Jacobson SG, Cideciyan AV, Flannery JG, Beltran WA, Aguirre GD. PMID: 30225158.
      View in: PubMed   Mentions:
    18. Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genet. 2018 08; 14(8):e1007504. Li L, Jiao X, D'Atri I, Ono F, Nelson R, Chan CC, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Coban Akdemir ZH, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF. PMID: 30157172.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    19. Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery. Mol Ther. 2018 09 05; 26(9):2282-2294. Cukras C, Wiley HE, Jeffrey BG, Sen HN, Turriff A, Zeng Y, Vijayasarathy C, Marangoni D, Ziccardi L, Kjellstrom S, Park TK, Hiriyanna S, Wright JF, Colosi P, Wu Z, Bush RA, Wei LL, Sieving PA. PMID: 30196853.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    20. IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet. 2018 Jul; 137(6-7):447-458. Chekuri A, Guru AA, Biswas P, Branham K, Borooah S, Soto-Hermida A, Hicks M, Khan NW, Matsui H, Alapati A, Raghavendra PB, Roosing S, Sarangapani S, Mathavan S, Telenti A, Heckenlively JR, Riazuddin SA, Frazer KA, Sieving PA, Ayyagari R. PMID: 29978320.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    21. Investigation of the effect of dietary docosahexaenoic acid (DHA) supplementation on macular function in subjects with autosomal recessive Stargardt macular dystrophy. Ophthalmic Genet. 2018 08; 39(4):477-486. MacDonald IM, Sieving PA. PMID: 29912604.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. 3-D retina organoids: Building platforms for therapies of the future. Cell Med. 2018; 10:2155179018773758. Mazerik JN, Becker S, Sieving PA. PMID: 32634188.
      View in: PubMed   Mentions:
    23. Analysis of Anatomic and Functional Measures in X-Linked Retinoschisis. Invest Ophthalmol Vis Sci. 2018 06 01; 59(7):2841-2847. Cukras CA, Huryn LA, Jeffrey BG, Turriff A, Sieving PA. PMID: 30025115.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Optical Coherence Tomography Minimum Intensity as an Objective Measure for the Detection of Hydroxychloroquine Toxicity. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):1953-1963. Allahdina AM, Stetson PF, Vitale S, Wong WT, Chew EY, Ferris FL, Sieving PA, Cukras C. PMID: 29677357.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Identification of Novel Deletions as the Underlying Cause of Retinal Degeneration in Two Pedigrees. Adv Exp Med Biol. 2018; 1074:229-236. Branham K, Guru AA, Kozak I, Biswas P, Othman M, Kishaba K, Mansoor H, Riazuddin S, Heckenlively JR, Riazuddin SA, Hejtmancik JF, Sieving PA, Ayyagari R. PMID: 29721948.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Tissue engineering: NIH competition to create 'eye in a dish'. Nature. 2017 06 14; 546(7658):352. Sieving PA. PMID: 28617468.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Homozygosity Mapping and Genetic Analysis of Autosomal Recessive Retinal Dystrophies in 144 Consanguineous Pakistani Families. Invest Ophthalmol Vis Sci. 2017 04 01; 58(4):2218-2238. Li L, Chen Y, Jiao X, Jin C, Jiang D, Tanwar M, Ma Z, Huang L, Ma X, Sun W, Chen J, Ma Y, M'hamdi O, Govindarajan G, Cabrera PE, Li J, Gupta N, Naeem MA, Khan SN, Riazuddin S, Akram J, Ayyagari R, Sieving PA, Riazuddin SA, Hejtmancik JF. PMID: 28418496.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    28. LONGITUDINAL STRUCTURAL CHANGES IN LATE-ONSET RETINAL DEGENERATION. Retina. 2016 Dec; 36(12):2348-2356. Cukras C, Flamendorf J, Wong WT, Ayyagari R, Cunningham D, Sieving PA. PMID: 27388725.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Establishing the involvement of the novel gene AGBL5 in retinitis pigmentosa by whole genome sequencing. Physiol Genomics. 2016 12 01; 48(12):922-927. Branham K, Matsui H, Biswas P, Guru AA, Hicks M, Suk JJ, Li H, Jakubosky D, Long T, Telenti A, Nariai N, Heckenlively JR, Frazer KA, Sieving PA, Ayyagari R. PMID: 27764769.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Retinal Structure and Gene Therapy Outcome in Retinoschisin-Deficient Mice Assessed by Spectral-Domain Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2016 07 01; 57(9):OCT277-87. Zeng Y, Petralia RS, Vijayasarathy C, Wu Z, Hiriyanna S, Song H, Wang YX, Sieving PA, Bush RA. PMID: 27409484.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    31. NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice. Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2864-75. Song H, Vijayasarathy C, Zeng Y, Marangoni D, Bush RA, Wu Z, Sieving PA. PMID: 27233035.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    32. Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis: Dose-Dependent Expression and Improved Retinal Structure and Function. Hum Gene Ther. 2016 May; 27(5):376-89. Bush RA, Zeng Y, Colosi P, Kjellstrom S, Hiriyanna S, Vijayasarathy C, Santos M, Li J, Wu Z, Sieving PA. PMID: 27036983.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    33. Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5287-92. Tolun G, Vijayasarathy C, Huang R, Zeng Y, Li Y, Steven AC, Sieving PA, Heymann JB. PMID: 27114531.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Basic science: Bedrock of progress. Science. 2016 Mar 25; 351(6280):1405. Collins FS, Anderson JM, Austin CP, Battey JF, Birnbaum LS, Briggs JP, Clayton JA, Cuthbert B, Eisinger RW, Fauci AS, Gallin JI, Gibbons GH, Glass RI, Gottesman MM, Gray PA, Green ED, Greider FB, Hodes R, Hudson KL, Humphreys B, Katz SI, Koob GF, Koroshetz WJ, Lauer MS, Lorsch JR, Lowy DR, McGowan JJ, Murray DM, Nakamura R, Norris A, Perez-Stable EJ, Pettigrew RI, Riley WT, Rodgers GP, Sieving PA, Somerman MJ, Spong CY, Tabak LA, Volkow ND, Wilder EL. PMID: 27013720.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    35. Ocular and systemic safety of a recombinant AAV8 vector for X-linked retinoschisis gene therapy: GLP studies in rabbits and Rs1-KO mice. Mol Ther Methods Clin Dev. 2016; 5:16011. Marangoni D, Bush RA, Zeng Y, Wei LL, Ziccardi L, Vijayasarathy C, Bartoe JT, Palyada K, Santos M, Hiriyanna S, Wu Z, Colosi P, Sieving PA. PMID: 27626041.
      View in: PubMed   Mentions:
    36. Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3-/- Mouse Model of Achromatopsia. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6810-22. Marangoni D, Vijayasarathy C, Bush RA, Wei LL, Wen R, Sieving PA. PMID: 26567794.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    37. Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer. J Clin Invest. 2015 Jul 01; 125(7):2891-903. Ou J, Vijayasarathy C, Ziccardi L, Chen S, Zeng Y, Marangoni D, Pope JG, Bush RA, Wu Z, Li W, Sieving PA. PMID: 26098217.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    38. Convergence of Human Genetics and Animal Studies: Gene Therapy for X-Linked Retinoschisis. Cold Spring Harb Perspect Med. 2015 Jun 22; 5(8):a017368. Bush RA, Wei LL, Sieving PA. PMID: 26101206.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    39. A long-term efficacy study of gene replacement therapy for RPGR-associated retinal degeneration. Hum Mol Genet. 2015 Jul 15; 24(14):3956-70. Wu Z, Hiriyanna S, Qian H, Mookherjee S, Campos MM, Gao C, Fariss R, Sieving PA, Li T, Colosi P, Swaroop A. PMID: 25877300.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    40. Biology and therapy of inherited retinal degenerative disease: insights from mouse models. Dis Model Mech. 2015 Feb; 8(2):109-29. Veleri S, Lazar CH, Chang B, Sieving PA, Banin E, Swaroop A. PMID: 25650393.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    41. Preclinical safety evaluation of a recombinant AAV8 vector for X-linked retinoschisis after intravitreal administration in rabbits. Hum Gene Ther Clin Dev. 2014 Dec; 25(4):202-11. Marangoni D, Wu Z, Wiley HE, Zeiss CJ, Vijayasarathy C, Zeng Y, Hiriyanna S, Bush RA, Wei LL, Colosi P, Sieving PA. PMID: 25211193.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    42. Cone responses in Usher syndrome types 1 and 2 by microvolt electroretinography. Invest Ophthalmol Vis Sci. 2014 Nov 25; 56(1):107-14. Zein WM, Falsini B, Tsilou ET, Turriff AE, Schultz JM, Friedman TB, Brewer CC, Zalewski CK, King KA, Muskett JA, Rehman AU, Morell RJ, Griffith AJ, Sieving PA. PMID: 25425308.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    43. Subjective and objective screening tests for hydroxychloroquine toxicity. Ophthalmology. 2015 Feb; 122(2):356-66. Cukras C, Huynh N, Vitale S, Wong WT, Ferris FL, Sieving PA. PMID: 25444344.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    44. Test-Retest Intervisit Variability of Functional and Structural Parameters in X-Linked Retinoschisis. Transl Vis Sci Technol. 2014 Sep; 3(5):5. Jeffrey BG, Cukras CA, Vitale S, Turriff A, Bowles K, Sieving PA. PMID: 25346871.
      View in: PubMed   Mentions:
    45. CNGB3-achromatopsia clinical trial with CNTF: diminished rod pathway responses with no evidence of improvement in cone function. Invest Ophthalmol Vis Sci. 2014 Sep 09; 55(10):6301-8. Zein WM, Jeffrey BG, Wiley HE, Turriff AE, Tumminia SJ, Tao W, Bush RA, Marangoni D, Wen R, Wei LL, Sieving PA. PMID: 25205868.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    46. Transgenic expression of constitutively active RAC1 disrupts mouse rod morphogenesis. Invest Ophthalmol Vis Sci. 2014 Apr 25; 55(4):2659-68. Song H, Bush RA, Vijayasarathy C, Fariss RN, Kjellstrom S, Sieving PA. PMID: 24651551.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    47. Sorting out co-occurrence of rare monogenic retinopathies: Stargardt disease co-existing with congenital stationary night blindness. Ophthalmic Genet. 2014 Mar; 35(1):51-6. Huynh N, Jeffrey BG, Turriff A, Sieving PA, Cukras CA. PMID: 24397708.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. AIPL1 implicated in the pathogenesis of two cases of autosomal recessive retinal degeneration. Mol Vis. 2014; 20:1-14. Li D, Jin C, Jiao X, Li L, Bushra T, Naeem MA, Butt NH, Husnain T, Sieving PA, Riazuddin S, Riazuddin SA, Hejtmancik JF. PMID: 24426771.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    49. Photoreceptor pathology in the X-linked retinoschisis (XLRS) mouse results in delayed rod maturation and impaired light driven transducin translocation. Adv Exp Med Biol. 2014; 801:559-66. Ziccardi L, Vijayasarathy C, Bush RA, Sieving PA. PMID: 24664744.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    50. Mutations in the small nuclear riboprotein 200 kDa gene (SNRNP200) cause 1.6% of autosomal dominant retinitis pigmentosa. Mol Vis. 2013; 19:2407-17. Bowne SJ, Sullivan LS, Avery CE, Sasser EM, Roorda A, Duncan JL, Wheaton DH, Birch DG, Branham KE, Heckenlively JR, Sieving PA, Daiger SP. PMID: 24319334.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    51. Characterization of novel RS1 exonic deletions in juvenile X-linked retinoschisis. Mol Vis. 2013; 19:2209-16. D'Souza L, Cukras C, Antolik C, Craig C, Lee JY, He H, Li S, Smaoui N, Hejtmancik JF, Sieving PA, Wang X. PMID: 24227916.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    52. Phenotypic conservation in patients with X-linked retinitis pigmentosa caused by RPGR mutations. JAMA Ophthalmol. 2013 Aug; 131(8):1016-25. Zahid S, Khan N, Branham K, Othman M, Karoukis AJ, Sharma N, Moncrief A, Mahmood MN, Sieving PA, Swaroop A, Heckenlively JR, Jayasundera T. PMID: 23681342.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    53. The golden era of ocular disease gene discovery: race to the finish. Clin Genet. 2013 Aug; 84(2):99-101. Swaroop A, Sieving PA. PMID: 23713688.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    54. Novel mutations in RPE65 identified in consanguineous Pakistani families with retinal dystrophy. Mol Vis. 2013; 19:1554-64. Kabir F, Naz S, Riazuddin SA, Naeem MA, Khan SN, Husnain T, Akram J, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 23878505.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    55. Molecular modeling indicates distinct classes of missense variants with mild and severe XLRS phenotypes. Hum Mol Genet. 2013 Dec 01; 22(23):4756-67. Sergeev YV, Vitale S, Sieving PA, Vincent A, Robson AG, Moore AT, Webster AR, Holder GE. PMID: 23847049.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    56. Mutations in RPGR and RP2 account for 15% of males with simplex retinal degenerative disease. Invest Ophthalmol Vis Sci. 2012 Dec 13; 53(13):8232-7. Branham K, Othman M, Brumm M, Karoukis AJ, Atmaca-Sonmez P, Yashar BM, Schwartz SB, Stover NB, Trzupek K, Wheaton D, Jennings B, Ciccarelli ML, Jayasundera KT, Lewis RA, Birch D, Bennett J, Sieving PA, Andreasson S, Duncan JL, Fishman GA, Iannaccone A, Weleber RG, Jacobson SG, Heckenlively JR, Swaroop A. PMID: 23150612.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    57. Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities. PLoS One. 2012; 7(11):e50205. Cukras C, Gaasterland T, Lee P, Gudiseva HV, Chavali VR, Pullakhandam R, Maranhao B, Edsall L, Soares S, Reddy GB, Sieving PA, Ayyagari R. PMID: 23189188.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    58. NEI audacious goals initiative to catalyze innovation. Invest Ophthalmol Vis Sci. 2012 Oct; 53(11):7149-50. Sieving PA. PMID: 23047720.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Fundus autofluorescence patterns in stargardt disease over time-reply. Arch Ophthalmol. 2012 Oct; 130(10):1354-5. Cukras CA, Wong WT, Caruso R, Cunningham D, Zein W, Sieving P. PMID: 23753838.
      View in: PubMed   Mentions:    Fields:    
    60. Loss of retinoschisin (RS1) cell surface protein in maturing mouse rod photoreceptors elevates the luminance threshold for light-driven translocation of transducin but not arrestin. J Neurosci. 2012 Sep 19; 32(38):13010-21. Ziccardi L, Vijayasarathy C, Bush RA, Sieving PA. PMID: 22993419.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    61. GNAT1 associated with autosomal recessive congenital stationary night blindness. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1353-61. Naeem MA, Chavali VR, Ali S, Iqbal M, Riazuddin S, Khan SN, Husnain T, Sieving PA, Ayyagari R, Riazuddin S, Hejtmancik JF, Riazuddin SA. PMID: 22190596.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    62. Biology of retinoschisin. Adv Exp Med Biol. 2012; 723:513-8. Vijayasarathy C, Ziccardi L, Sieving PA. PMID: 22183371.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    63. CNTF and retina. Prog Retin Eye Res. 2012 Mar; 31(2):136-51. Wen R, Tao W, Li Y, Sieving PA. PMID: 22182585.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    64. X-linked retinoschisis: RS1 mutation severity and age affect the ERG phenotype in a cohort of 68 affected male subjects. Invest Ophthalmol Vis Sci. 2011 Nov 29; 52(12):9250-6. Bowles K, Cukras C, Turriff A, Sergeev Y, Vitale S, Bush RA, Sieving PA. PMID: 22039241.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    65. Centrifugal expansion of fundus autofluorescence patterns in Stargardt disease over time. Arch Ophthalmol. 2012 Feb; 130(2):171-9. Cukras CA, Wong WT, Caruso R, Cunningham D, Zein W, Sieving PA. PMID: 21987580.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    66. Association of pathogenic mutations in TULP1 with retinitis pigmentosa in consanguineous Pakistani families. Arch Ophthalmol. 2011 Oct; 129(10):1351-7. Iqbal M, Naeem MA, Riazuddin SA, Ali S, Farooq T, Qazi ZA, Khan SN, Husnain T, Riazuddin S, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 21987678.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    67. Mutations in the ß-subunit of rod phosphodiesterase identified in consanguineous Pakistani families with autosomal recessive retinitis pigmentosa. Mol Vis. 2011; 17:1373-80. Ali S, Riazuddin SA, Shahzadi A, Nasir IA, Khan SN, Husnain T, Akram J, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 21655355.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    68. Mutations in RLBP1 associated with fundus albipunctatus in consanguineous Pakistani families. Br J Ophthalmol. 2011 Jul; 95(7):1019-24. Naz S, Ali S, Riazuddin SA, Farooq T, Butt NH, Zafar AU, Khan SN, Husnain T, Macdonald IM, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 21447491.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    69. Molecular mechanisms leading to null-protein product from retinoschisin (RS1) signal-sequence mutants in X-linked retinoschisis (XLRS) disease. Hum Mutat. 2010 Nov; 31(11):1251-60. Vijayasarathy C, Sui R, Zeng Y, Yang G, Xu F, Caruso RC, Lewis RA, Ziccardi L, Sieving PA. PMID: 20809529.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    70. A mutation in SLC24A1 implicated in autosomal-recessive congenital stationary night blindness. Am J Hum Genet. 2010 Oct 08; 87(4):523-31. Riazuddin SA, Shahzadi A, Zeitz C, Ahmed ZM, Ayyagari R, Chavali VR, Ponferrada VG, Audo I, Michiels C, Lancelot ME, Nasir IA, Zafar AU, Khan SN, Husnain T, Jiao X, MacDonald IM, Riazuddin S, Sieving PA, Katsanis N, Hejtmancik JF. PMID: 20850105.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    71. A mutation in ZNF513, a putative regulator of photoreceptor development, causes autosomal-recessive retinitis pigmentosa. Am J Hum Genet. 2010 Sep 10; 87(3):400-9. Li L, Nakaya N, Chavali VR, Ma Z, Jiao X, Sieving PA, Riazuddin S, Tomarev SI, Ayyagari R, Riazuddin SA, Hejtmancik JF. PMID: 20797688.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    72. Long-term 12 year follow-up of X-linked congenital retinoschisis. Ophthalmic Genet. 2010 Sep; 31(3):114-25. Kjellström S, Vijayasarathy C, Ponjavic V, Sieving PA, Andréasson S. PMID: 20569020.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    73. Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study. Biochemistry. 2010 Aug 24; 49(33):7023-32. Kotova S, Vijayasarathy C, Dimitriadis EK, Ikonomou L, Jaffe H, Sieving PA. PMID: 20677810.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    74. Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12710-5. Raz-Prag D, Grimes WN, Fariss RN, Vijayasarathy C, Campos MM, Bush RA, Diamond JS, Sieving PA. PMID: 20616020.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    75. Nonsense mutation in MERTK causes autosomal recessive retinitis pigmentosa in a consanguineous Pakistani family. Br J Ophthalmol. 2010 Aug; 94(8):1094-9. Shahzadi A, Riazuddin SA, Ali S, Li D, Khan SN, Husnain T, Akram J, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 20538656.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    76. A splice-site mutation in a retina-specific exon of BBS8 causes nonsyndromic retinitis pigmentosa. Am J Hum Genet. 2010 May 14; 86(5):805-12. Riazuddin SA, Iqbal M, Wang Y, Masuda T, Chen Y, Bowne S, Sullivan LS, Waseem NH, Bhattacharya S, Daiger SP, Zhang K, Khan SN, Riazuddin S, Hejtmancik JF, Sieving PA, Zack DJ, Katsanis N. PMID: 20451172.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    77. A novel locus for autosomal recessive retinitis pigmentosa in a consanguineous Pakistani family maps to chromosome 2p. Am J Ophthalmol. 2010 May; 149(5):861-6. Naz S, Riazuddin SA, Li L, Shahid M, Kousar S, Sieving PA, Hejtmancik JF, Riazuddin S. PMID: 20227676.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    78. At the frontier of vision research: the National Eye Institute celebrates 40 years. Am J Ophthalmol. 2010 Feb; 149(2):179-81. Sieving PA. PMID: 20103048.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    79. Molecular modeling of retinoschisin with functional analysis of pathogenic mutations from human X-linked retinoschisis. Hum Mol Genet. 2010 Apr 01; 19(7):1302-13. Sergeev YV, Caruso RC, Meltzer MR, Smaoui N, MacDonald IM, Sieving PA. PMID: 20061330.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    80. Long-term follow-up of a family with dominant X-linked retinitis pigmentosa. Eye (Lond). 2010 May; 24(5):764-74. Wu DM, Khanna H, Atmaca-Sonmez P, Sieving PA, Branham K, Othman M, Swaroop A, Daiger SP, Heckenlively JR. PMID: 19893586.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    81. Null retinoschisin-protein expression from an RS1 c354del1-ins18 mutation causing progressive and severe XLRS in a cross-sectional family study. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5375-83. Vijayasarathy C, Ziccardi L, Zeng Y, Smaoui N, Caruso RC, Sieving PA. PMID: 19474399.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    82. Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9397-402. Haruta M, Bush RA, Kjellstrom S, Vijayasarathy C, Zeng Y, Le YZ, Sieving PA. PMID: 19470639.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    83. Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse. Gene Ther. 2009 Jul; 16(7):916-26. Park TK, Wu Z, Kjellstrom S, Zeng Y, Bush RA, Sieving PA, Colosi P. PMID: 19458650.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    84. The effects of transient retinal detachment on cavity size and glial and neural remodeling in a mouse model of X-linked retinoschisis. Invest Ophthalmol Vis Sci. 2009 Aug; 50(8):3977-84. Luna G, Kjellstrom S, Verardo MR, Lewis GP, Byun J, Sieving PA, Fisher SK. PMID: 19387072.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    85. Photoreceptor protection by adeno-associated virus-mediated LEDGF expression in the RCS rat model of retinal degeneration: probing the mechanism. Invest Ophthalmol Vis Sci. 2009 Aug; 50(8):3897-906. Raz-Prag D, Zeng Y, Sieving PA, Bush RA. PMID: 19324854.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    86. Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration. Mol Vis. 2008; 14:2227-36. Ahmed ZM, Kjellstrom S, Haywood-Watson RJ, Bush RA, Hampton LL, Battey JF, Riazuddin S, Frolenkov G, Sieving PA, Friedman TB. PMID: 19057657.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    87. Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin. J Neurosci. 2008 Nov 05; 28(45):11662-72. Dizhoor AM, Woodruff ML, Olshevskaya EV, Cilluffo MC, Cornwall MC, Sieving PA, Fain GL. PMID: 18987202.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    88. Synaptic pathology in retinoschisis knockout (Rs1-/y) mouse retina and modification by rAAV-Rs1 gene delivery. Invest Ophthalmol Vis Sci. 2008 Aug; 49(8):3677-86. Takada Y, Vijayasarathy C, Zeng Y, Kjellstrom S, Bush RA, Sieving PA. PMID: 18660429.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    89. Genomics in the era of molecular ophthalmology: reflections on the National Ophthalmic Disease Genotyping Network (eyeGENE). Arch Ophthalmol. 2008 Mar; 126(3):424-5. Brooks BP, Macdonald IM, Tumminia SJ, Smaoui N, Blain D, Nezhuvingal AA, Sieving PA. PMID: 18332328.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    90. Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):442-52. Machida S, Raz-Prag D, Fariss RN, Sieving PA, Bush RA. PMID: 18172124.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    91. Organization and molecular interactions of retinoschisin in photoreceptors. Adv Exp Med Biol. 2008; 613:291-7. Vijayasarathy C, Takada Y, Zeng Y, Bush RA, Sieving PA. PMID: 18188957.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    92. Eyeing a new network. Science. 2007 Nov 16; 318(5853):1068. MacDonald IM, Brooks BP, Sieving PA. PMID: 18006726.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    93. Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark. J Neurosci. 2007 Aug 15; 27(33):8805-15. Woodruff ML, Olshevskaya EV, Savchenko AB, Peshenko IV, Barrett R, Bush RA, Sieving PA, Fain GL, Dizhoor AM. PMID: 17699662.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    94. CNGB3 achromatopsia with progressive loss of residual cone function and impaired rod-mediated function. Invest Ophthalmol Vis Sci. 2007 Aug; 48(8):3864-71. Khan NW, Wissinger B, Kohl S, Sieving PA. PMID: 17652762.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    95. Retinoschisin gene therapy and natural history in the Rs1h-KO mouse: long-term rescue from retinal degeneration. Invest Ophthalmol Vis Sci. 2007 Aug; 48(8):3837-45. Kjellstrom S, Bush RA, Zeng Y, Takada Y, Sieving PA. PMID: 17652759.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    96. Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene. Hum Genet. 2007 Nov; 122(3-4):293-9. Zhang Q, Zulfiqar F, Xiao X, Riazuddin SA, Ahmad Z, Caruso R, MacDonald I, Sieving P, Riazuddin S, Hejtmancik JF. PMID: 17605048.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    97. Preventing blindness in retinal disease: ciliary neurotrophic factor intraocular implants. Can J Ophthalmol. 2007 Jun; 42(3):399-402. MacDonald IM, Sauvé Y, Sieving PA. PMID: 17508034.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    98. Retinoschisin is a peripheral membrane protein with affinity for anionic phospholipids and affected by divalent cations. Invest Ophthalmol Vis Sci. 2007 Mar; 48(3):991-1000. Vijayasarathy C, Takada Y, Zeng Y, Bush RA, Sieving PA. PMID: 17325137.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    99. Genetic ophthalmology and the era of clinical care. JAMA. 2007 Feb 21; 297(7):733-6. Sieving PA, Collins FS. PMID: 17315303.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    100. Molecular testing for hereditary retinal disease as part of clinical care. Arch Ophthalmol. 2007 Feb; 125(2):252-8. Downs K, Zacks DN, Caruso R, Karoukis AJ, Branham K, Yashar BM, Haimann MH, Trzupek K, Meltzer M, Blain D, Richards JE, Weleber RG, Heckenlively JR, Sieving PA, Ayyagari R. PMID: 17296903.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    101. Regulation of rod phototransduction machinery by ciliary neurotrophic factor. J Neurosci. 2006 Dec 27; 26(52):13523-30. Wen R, Song Y, Kjellstrom S, Tanikawa A, Liu Y, Li Y, Zhao L, Bush RA, Laties AM, Sieving PA. PMID: 17192435.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    102. Mutations in the gene encoding the alpha-subunit of rod phosphodiesterase in consanguineous Pakistani families. Mol Vis. 2006 Oct 26; 12:1283-91. Riazuddin SA, Zulfiqar F, Zhang Q, Yao W, Li S, Jiao X, Shahzadi A, Amer M, Iqbal M, Hussnain T, Sieving PA, Riazuddin S, Hejtmancik JF. PMID: 17110911.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    103. Elovl4 5-bp-deletion knock-in mice develop progressive photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2006 Oct; 47(10):4558-68. Vasireddy V, Jablonski MM, Mandal MN, Raz-Prag D, Wang XF, Nizol L, Iannaccone A, Musch DC, Bush RA, Salem N, Sieving PA, Ayyagari R. PMID: 17003453.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    104. Retinoschisin expression and localization in rodent and human pineal and consequences of mouse RS1 gene knockout. Mol Vis. 2006 Sep 28; 12:1108-16. Takada Y, Fariss RN, Muller M, Bush RA, Rushing EJ, Sieving PA. PMID: 17093404.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    105. RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet. 2006 Oct; 2(10):e177. Aslanukov A, Bhowmick R, Guruju M, Oswald J, Raz D, Bush RA, Sieving PA, Lu X, Bock CB, Ferreira PA. PMID: 17069463.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    106. Congenital X-linked retinoschisis classification system. Retina. 2006 Sep; 26(7 Suppl):S61-4. Prenner JL, Capone A, Ciaccia S, Takada Y, Sieving PA, Trese MT. PMID: 16946682.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    107. Identification and characterization of two mature isoforms of retinoschisin in murine retina. Biochem Biophys Res Commun. 2006 Oct 13; 349(1):99-105. Vijayasarathy C, Gawinowicz MA, Zeng Y, Takada Y, Bush RA, Sieving PA. PMID: 16930543.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    108. Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3603-11. Raz-Prag D, Ayyagari R, Fariss RN, Mandal MN, Vasireddy V, Majchrzak S, Webber AL, Bush RA, Salem N, Petrukhin K, Sieving PA. PMID: 16877435.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    109. Ames Waltzer deaf mice have reduced electroretinogram amplitudes and complex alternative splicing of Pcdh15 transcripts. Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):3074-84. Haywood-Watson RJ, Ahmed ZM, Kjellstrom S, Bush RA, Takada Y, Hampton LL, Battey JF, Sieving PA, Friedman TB. PMID: 16799054.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    110. Response to: "Rescuing the NIH before it is too late". J Clin Invest. 2006 Jun; 116(6):1462-3. Alexander DF, Alving BM, Battey JF, Berg JM, Collins FS, Fauci AS, Gallin JI, Grady PA, Hodes RJ, Hrynkow SH, Insel TR, Jones JF, Katz SI, Landis SC, Li TK, Lindberg DA, Nabel EG, Niederhuber JE, Pettigrew RI, Rodgers GP, Ruffin J, Scarpa A, Schwartz DA, Sieving PA, Straus SE, Tabak LA, Volkow ND. PMID: 16648877.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    111. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3896-901. Sieving PA, Caruso RC, Tao W, Coleman HR, Thompson DJ, Fullmer KR, Bush RA. PMID: 16505355.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansCellsCTClinical Trials
    112. Fostering partnerships: The National Institutes of Health (NIH) Mission. Retina. 2005 Dec; 25(8 Suppl):S84-S85. Sieving PA. PMID: 16374355.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    113. The national eye institute: translational clinical research initiatives on inherited and orphan retinal diseases: personal observations. Retina. 2005 Dec; 25(8 Suppl):S8-S9. Sieving PA. PMID: 16374351.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    114. A variant form of Oguchi disease mapped to 13q34 associated with partial deletion of GRK1 gene. Mol Vis. 2005 Nov 14; 11:977-85. Zhang Q, Zulfiqar F, Riazuddin SA, Xiao X, Yasmeen A, Rogan PK, Caruso R, Sieving PA, Riazuddin S, Hejtmancik JF. PMID: 16319817.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    115. Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. Hum Mol Genet. 2005 Dec 15; 14(24):3865-75. Thompson DA, Janecke AR, Lange J, Feathers KL, Hübner CA, McHenry CL, Stockton DW, Rammesmayer G, Lupski JR, Antinolo G, Ayuso C, Baiget M, Gouras P, Heckenlively JR, den Hollander A, Jacobson SG, Lewis RA, Sieving PA, Wissinger B, Yzer S, Zrenner E, Utermann G, Gal A. PMID: 16269441.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    116. Severe autosomal recessive retinitis pigmentosa maps to chromosome 1p13.3-p21.2 between D1S2896 and D1S457 but outside ABCA4. Hum Genet. 2005 Dec; 118(3-4):356-65. Zhang Q, Zulfiqar F, Xiao X, Riazuddin SA, Ayyagari R, Sabar F, Caruso R, Sieving PA, Riazuddin S, Hejtmancik JF. PMID: 16189710.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    117. Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. Invest Ophthalmol Vis Sci. 2005 Sep; 46(9):3363-71. Ayyagari R, Mandal MN, Karoukis AJ, Chen L, McLaren NC, Lichter M, Wong DT, Hitchcock PF, Caruso RC, Moroi SE, Maumenee IH, Sieving PA. PMID: 16123441.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    118. Sequencing arrays for screening multiple genes associated with early-onset human retinal degenerations on a high-throughput platform. Invest Ophthalmol Vis Sci. 2005 Sep; 46(9):3355-62. Mandal MN, Heckenlively JR, Burch T, Chen L, Vasireddy V, Koenekoop RK, Sieving PA, Ayyagari R. PMID: 16123440.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    119. Stargardt-like macular dystrophy protein ELOVL4 exerts a dominant negative effect by recruiting wild-type protein into aggresomes. Mol Vis. 2005 Aug 30; 11:665-76. Vasireddy V, Vijayasarathy C, Huang J, Wang XF, Jablonski MM, Petty HR, Sieving PA, Ayyagari R. PMID: 16163264.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    120. Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice. Invest Ophthalmol Vis Sci. 2005 Jul; 46(7):2540-51. Brzezinski JA, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T. PMID: 15980246.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    121. Autosomal recessive retinitis pigmentosa is associated with mutations in RP1 in three consanguineous Pakistani families. Invest Ophthalmol Vis Sci. 2005 Jul; 46(7):2264-70. Riazuddin SA, Zulfiqar F, Zhang Q, Sergeev YV, Qazi ZA, Husnain T, Caruso R, Riazuddin S, Sieving PA, Hejtmancik JF. PMID: 15980210.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    122. CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia. Eur J Hum Genet. 2005 Mar; 13(3):302-8. Kohl S, Varsanyi B, Antunes GA, Baumann B, Hoyng CB, Jägle H, Rosenberg T, Kellner U, Lorenz B, Salati R, Jurklies B, Farkas A, Andreasson S, Weleber RG, Jacobson SG, Rudolph G, Castellan C, Dollfus H, Legius E, Anastasi M, Bitoun P, Lev D, Sieving PA, Munier FL, Zrenner E, Sharpe LT, Cremers FP, Wissinger B. PMID: 15657609.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    123. A retinal neuronal developmental wave of retinoschisin expression begins in ganglion cells during layer formation. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3302-12. Takada Y, Fariss RN, Tanikawa A, Zeng Y, Carper D, Bush R, Sieving PA. PMID: 15326155.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    124. RS-1 Gene Delivery to an Adult Rs1h Knockout Mouse Model Restores ERG b-Wave with Reversal of the Electronegative Waveform of X-Linked Retinoschisis. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3279-85. Zeng Y, Takada Y, Kjellstrom S, Hiriyanna K, Tanikawa A, Wawrousek E, Smaoui N, Caruso R, Bush RA, Sieving PA. PMID: 15326152.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimals
    125. Primate Retinal Signaling Pathways: Suppressing ON-Pathway Activity in Monkey With Glutamate Analogues Mimics Human CSNB1-NYX Genetic Night Blindness. J Neurophysiol. 2005 Jan; 93(1):481-92. Khan NW, Kondo M, Hiriyanna KT, Jamison JA, Bush RA, Sieving PA. PMID: 15331616.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    126. Encapsulated cell-based intraocular delivery of ciliary neurotrophic factor in normal rabbit: dose-dependent effects on ERG and retinal histology. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2420-30. Bush RA, Lei B, Tao W, Raz D, Chan CC, Cox TA, Santos-Muffley M, Sieving PA. PMID: 15223826.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    127. Healthy Vision Month--May 2004: focus is on diabetic retinopathy. Optometry. 2004 May; 75(5):271-3. Sieving PA. PMID: 15141816.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    128. MERTK arginine-844-cysteine in a patient with severe rod-cone dystrophy: loss of mutant protein function in transfected cells. Invest Ophthalmol Vis Sci. 2004 May; 45(5):1456-63. McHenry CL, Liu Y, Feng W, Nair AR, Feathers KL, Ding X, Gal A, Vollrath D, Sieving PA, Thompson DA. PMID: 15111602.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    129. Limits to growth: why neuroscience needs large-scale science. Nat Neurosci. 2004 May; 7(5):426-7. Insel TR, Volkow ND, Landis SC, Li TK, Battey JF, Sieving P. PMID: 15114352.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    130. Atrophic macular degeneration mutations in ELOVL4 result in the intracellular misrouting of the protein. Genomics. 2004 Apr; 83(4):615-25. Ambasudhan R, Wang X, Jablonski MM, Thompson DA, Lagali PS, Wong PW, Sieving PA, Ayyagari R. PMID: 15028284.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    131. Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression. Genomics. 2004 Apr; 83(4):626-35. Mandal MN, Ambasudhan R, Wong PW, Gage PJ, Sieving PA, Ayyagari R. PMID: 15028285.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    132. Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease. Am J Hum Genet. 2004 Mar; 74(3):482-94. Abecasis GR, Yashar BM, Zhao Y, Ghiasvand NM, Zareparsi S, Branham KE, Reddick AC, Trager EH, Yoshida S, Bahling J, Filippova E, Elner S, Johnson MW, Vine AK, Sieving PA, Jacobson SG, Richards JE, Swaroop A. PMID: 14968411.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    133. Long anterior zonules and pigment dispersion. Am J Ophthalmol. 2003 Dec; 136(6):1176-8. Moroi SE, Lark KK, Sieving PA, Nouri-Mahdavi K, Schlötzer-Schrehardt U, Katz GJ, Ritch R. PMID: 14644241.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    134. Optic nerve dysplasia and renal insufficiency in a family with a novel PAX2 mutation, Arg115X: further ophthalmologic delineation of the renal-coloboma syndrome. Ophthalmic Genet. 2003 Dec; 24(4):191-202. Schimmenti LA, Manligas GS, Sieving PA. PMID: 14566649.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    135. PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23. Hum Mol Genet. 2003 Dec 15; 12(24):3215-23. Ahmed ZM, Riazuddin S, Ahmad J, Bernstein SL, Guo Y, Sabar MF, Sieving P, Riazuddin S, Griffith AJ, Friedman TB, Belyantseva IA, Wilcox ER. PMID: 14570705.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    136. Clinical diagnoses that overlap with choroideremia. Can J Ophthalmol. 2003 Aug; 38(5):364-72; quiz 372. Lee TK, McTaggart KE, Sieving PA, Heckenlively JR, Levin AV, Greenberg J, Weleber RG, Tong PY, Anhalt EF, Powell BR, MacDonald IM. PMID: 12956277.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    137. Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4742-7. Radu RA, Mata NL, Nusinowitz S, Liu X, Sieving PA, Travis GH. PMID: 12671074.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    138. Evaluation of the ELOVL4 gene in patients with autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. Mol Vis. 2003 Feb 18; 9:49-51. Rivolta C, Ayyagari R, Sieving PA, Berson EL, Dryja TP. PMID: 12592226.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    139. Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. Mol Vis. 2003 Jan 24; 9:14-7. Acar C, Mears AJ, Yashar BM, Maheshwary AS, Andreasson S, Baldi A, Sieving PA, Iannaccone A, Musarella MA, Jacobson SG, Swaroop A. PMID: 12552256.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    140. X-linked recessive atrophic macular degeneration from RPGR mutation. Genomics. 2002 Aug; 80(2):166-71. Ayyagari R, Demirci FY, Liu J, Bingham EL, Stringham H, Kakuk LE, Boehnke M, Gorin MB, Richards JE, Sieving PA. PMID: 12160730.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    141. Post-photoreceptoral activity dominates primate photopic 32-Hz ERG for sine-, square-, and pulsed stimuli. Invest Ophthalmol Vis Sci. 2002 Jul; 43(7):2500-7. Kondo M, Sieving PA. PMID: 12091456.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    142. Retinal cAMP levels during the progression of retinal degeneration in rhodopsin P23H and S334ter transgenic rats. Invest Ophthalmol Vis Sci. 2002 May; 43(5):1655-61. Traverso V, Bush RA, Sieving PA, Deretic D. PMID: 11980887.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    143. A comprehensive mutation analysis of RP2 and RPGR in a North American cohort of families with X-linked retinitis pigmentosa. Am J Hum Genet. 2002 Jun; 70(6):1545-54. Breuer DK, Yashar BM, Filippova E, Hiriyanna S, Lyons RH, Mears AJ, Asaye B, Acar C, Vervoort R, Wright AF, Musarella MA, Wheeler P, MacDonald I, Iannaccone A, Birch D, Hoffman DR, Fishman GA, Heckenlively JR, Jacobson SG, Sieving PA, Swaroop A. PMID: 11992260.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    144. Clinical course and visual function in a family with mutations in the RPE65 gene. Arch Ophthalmol. 2002 Jan; 120(1):55-61. Felius J, Thompson DA, Khan NW, Bingham EL, Jamison JA, Kemp JA, Sieving PA. PMID: 11786058.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    145. Analysis of photoreceptor function and inner retinal activity in juvenile X-linked retinoschisis. Vision Res. 2001 Dec; 41(28):3931-42. Khan NW, Jamison JA, Kemp JA, Sieving PA. PMID: 11738458.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    146. Nrl is required for rod photoreceptor development. Nat Genet. 2001 Dec; 29(4):447-52. Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, Saunders TL, Sieving PA, Swaroop A. PMID: 11694879.
      View in: PubMed   Mentions: 355     Fields:    Translation:AnimalsCells
    147. Evaluation of the ELOVL4 gene in patients with age-related macular degeneration. Ophthalmic Genet. 2001 Dec; 22(4):233-9. Ayyagari R, Zhang K, Hutchinson A, Yu Z, Swaroop A, Kakuk LE, Seddon JM, Bernstein PS, Lewis RA, Tammur J, Yang Z, Li Y, Zhang H, Yashar BM, Liu J, Petrukhin K, Sieving PA, Allikmets R. PMID: 11803489.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    148. Bietti crystalline retinopathy and juvenile retinoschisis in a family with a novel RS1 mutation. Arch Ophthalmol. 2001 Nov; 119(11):1719-21. Weinberg DV, Sieving PA, Bingham EL, Jampol LM, Mets MB. PMID: 11709029.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    149. Constitutive "light" adaptation in rods from G90D rhodopsin: a mechanism for human congenital nightblindness without rod cell loss. J Neurosci. 2001 Aug 01; 21(15):5449-60. Sieving PA, Fowler ML, Bush RA, Machida S, Calvert PD, Green DG, Makino CL, McHenry CL. PMID: 11466416.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    150. Fifteen years of work: the COMS outcomes for medium-sized choroidal melanoma. Arch Ophthalmol. 2001 Jul; 119(7):1067-8. Sieving PA. PMID: 11448330.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    151. Mutations in the gene encoding lecithin retinol acyltransferase are associated with early-onset severe retinal dystrophy. Nat Genet. 2001 Jun; 28(2):123-4. Thompson DA, Li Y, McHenry CL, Carlson TJ, Ding X, Sieving PA, Apfelstedt-Sylla E, Gal A. PMID: 11381255.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    152. Characterization of the rod photoresponse isolated from the dark-adapted primate ERG. Vis Neurosci. 2001 May-Jun; 18(3):445-55. Jamison JA, Bush RA, Lei B, Sieving PA. PMID: 11497421.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    153. Comparative structural and functional analysis of photoreceptor neurons of Rho-/- mice reveal increased survival on C57BL/6J in comparison to 129Sv genetic background. Vis Neurosci. 2001 May-Jun; 18(3):437-43. Humphries MM, Kiang S, McNally N, Donovan MA, Sieving PA, Bush RA, Machida S, Cotter T, Hobson A, Farrar J, Humphries P, Kenna P. PMID: 11497420.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    154. Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats. Invest Ophthalmol Vis Sci. 2001 Apr; 42(5):1087-95. Machida S, Chaudhry P, Shinohara T, Singh DP, Reddy VN, Chylack LT, Sieving PA, Bush RA. PMID: 11274090.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCellsPHPublic Health
    155. Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1835-40. Sieving PA, Chaudhry P, Kondo M, Provenzano M, Wu D, Carlson TJ, Bush RA, Thompson DA. PMID: 11172037.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    156. Primate photopic sine-wave flicker ERG: vector modeling analysis of component origins using glutamate analogs. Invest Ophthalmol Vis Sci. 2001 Jan; 42(1):305-12. Kondo M, Sieving PA. PMID: 11133883.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    157. A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy. Nat Genet. 2001 Jan; 27(1):89-93. Zhang K, Kniazeva M, Han M, Li W, Yu Z, Yang Z, Li Y, Metzker ML, Allikmets R, Zack DJ, Kakuk LE, Lagali PS, Wong PW, MacDonald IM, Sieving PA, Figueroa DJ, Austin CP, Gould RJ, Ayyagari R, Petrukhin K. PMID: 11138005.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    158. Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4293-9. Thompson DA, Gyürüs P, Fleischer LL, Bingham EL, McHenry CL, Apfelstedt-Sylla E, Zrenner E, Lorenz B, Richards JE, Jacobson SG, Sieving PA, Gal A. PMID: 11095629.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    159. P23H rhodopsin transgenic rat: correlation of retinal function with histopathology. Invest Ophthalmol Vis Sci. 2000 Sep; 41(10):3200-9. Machida S, Kondo M, Jamison JA, Khan NW, Kononen LT, Sugawara T, Bush RA, Sieving PA. PMID: 10967084.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    160. Remapping of the RP15 locus for X-linked cone-rod degeneration to Xp11.4-p21.1, and identification of a de novo insertion in the RPGR exon ORF15. Am J Hum Genet. 2000 Oct; 67(4):1000-3. Mears AJ, Hiriyanna S, Vervoort R, Yashar B, Gieser L, Fahrner S, Daiger SP, Heckenlively JR, Sieving PA, Wright AF, Swaroop A. PMID: 10970770.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    161. Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21. Hum Mol Genet. 2000 Sep 01; 9(14):2107-16. Kohl S, Baumann B, Broghammer M, Jägle H, Sieving P, Kellner U, Spegal R, Anastasi M, Zrenner E, Sharpe LT, Wissinger B. PMID: 10958649.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    162. The effect of calcium channel blocker diltiazem on photoreceptor degeneration in the rhodopsin Pro213His rat. Invest Ophthalmol Vis Sci. 2000 Aug; 41(9):2697-701. Bush RA, Kononen L, Machida S, Sieving PA. PMID: 10937585.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    163. Phenotypic expression of juvenile X-linked retinoschisis in Swedish families with different mutations in the XLRS1 gene. Arch Ophthalmol. 2000 Aug; 118(8):1098-104. Eksandh LC, Ponjavic V, Ayyagari R, Bingham EL, Hiriyanna KT, Andréasson S, Ehinger B, Sieving PA. PMID: 10922205.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    164. Spectrum of color gene deletions and phenotype in patients with blue cone monochromacy. Hum Genet. 2000 Jul; 107(1):75-82. Ayyagari R, Kakuk LE, Bingham EL, Szczesny JJ, Kemp J, Toda Y, Felius J, Sieving PA. PMID: 10982039.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    165. Quantitative relationship of the scotopic and photopic ERG to photoreceptor cell loss in light damaged rats. Exp Eye Res. 2000 May; 70(5):693-705. Sugawara T, Sieving PA, Bush RA. PMID: 10870528.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    166. Retinal toxicity of commercial intravitreal tissue plasminogen activator solution in cat eyes. Arch Ophthalmol. 2000 May; 118(5):659-63. Hrach CJ, Johnson MW, Hassan AS, Lei B, Sieving PA, Elner VM. PMID: 10815158.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    167. Autosomal dominant macular atrophy at 6q14 excludes CORD7 and MCDR1/PBCRA loci. Invest Ophthalmol Vis Sci. 2000 Jan; 41(1):248-55. Griesinger IB, Sieving PA, Ayyagari R. PMID: 10634627.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    168. Human melanoma-associated retinopathy (MAR) antibodies alter the retinal ON-response of the monkey ERG in vivo. Invest Ophthalmol Vis Sci. 2000 Jan; 41(1):262-6. Lei B, Bush RA, Milam AH, Sieving PA. PMID: 10634629.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    169. Autosomal dominant hemorrhagic macular dystrophy not associated with the TIMP3 gene. Arch Ophthalmol. 2000 Jan; 118(1):85-92. Ayyagari R, Griesinger IB, Bingham E, Lark KK, Moroi SE, Sieving PA. PMID: 10636420.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    170. Juvenile X-linked retinoschisis from XLRS1 Arg213Trp mutation with preservation of the electroretinogram scotopic b-wave. Am J Ophthalmol. 1999 Aug; 128(2):179-84. Sieving PA, Bingham EL, Kemp J, Richards J, Hiriyanna K. PMID: 10458173.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    171. Bilateral macular atrophy in blue cone monochromacy (BCM) with loss of the locus control region (LCR) and part of the red pigment gene. Mol Vis. 1999 Jul 28; 5:13. Ayyagari R, Kakuk LE, Coats CL, Bingham EL, Toda Y, Felius J, Sieving PA. PMID: 10427103.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    172. Structural and functional rescue of murine rod photoreceptors by human rhodopsin transgene. Hum Mol Genet. 1999 Jul; 8(7):1309-12. McNally N, Kenna P, Humphries MM, Hobson AH, Khan NW, Bush RA, Sieving PA, Humphries P, Farrar GJ. PMID: 10369877.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    173. Bestrophin gene mutations in patients with Best vitelliform macular dystrophy. Genomics. 1999 May 15; 58(1):98-101. Caldwell GM, Kakuk LE, Griesinger IB, Simpson SA, Nowak NJ, Small KW, Maumenee IH, Rosenfeld PJ, Sieving PA, Shows TB, Ayyagari R. PMID: 10331951.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    174. A Colombian family with X-linked juvenile retinoschisis with three affected females finding of a frameshift mutation. Ophthalmic Genet. 1999 Mar; 20(1):37-43. Mendoza-Londono R, Hiriyanna KT, Bingham EL, Rodriguez F, Shastry BS, Rodriguez A, Sieving PA, Tamayo ML. PMID: 10415464.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    175. The electroretinogram of the rhodopsin knockout mouse. Vis Neurosci. 1999 Mar-Apr; 16(2):391-8. Toda K, Bush RA, Humphries P, Sieving PA. PMID: 10367972.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    176. Protein-truncation mutations in the RP2 gene in a North American cohort of families with X-linked retinitis pigmentosa. Am J Hum Genet. 1999 Mar; 64(3):897-900. Mears AJ, Gieser L, Yan D, Chen C, Fahrner S, Hiriyanna S, Fujita R, Jacobson SG, Sieving PA, Swaroop A. PMID: 10053026.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    177. Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function. Hum Mol Genet. 1999 Feb; 8(2):299-305. Swaroop A, Wang QL, Wu W, Cook J, Coats C, Xu S, Chen S, Zack DJ, Sieving PA. PMID: 9931337.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    178. Identification and characterization of the human homologue (RAI2) of a mouse retinoic acid-induced gene in Xp22. Genomics. 1999 Feb 01; 55(3):275-83. Walpole SM, Hiriyana KT, Nicolaou A, Bingham EL, Durham J, Vaudin M, Ross MT, Yates JR, Sieving PA, Trump D. PMID: 10049581.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    179. Novel mutations in XLRS1 causing retinoschisis, including first evidence of putative leader sequence change. Hum Mutat. 1999; 14(5):423-7. Hiriyanna KT, Bingham EL, Yashar BM, Ayyagari R, Fishman G, Small KW, Weinberg DV, Weleber RG, Lewis RA, Andreasson S, Richards JE, Sieving PA. PMID: 10533068.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    180. Juvenile retinoschisis: a model for molecular diagnostic testing of X-linked ophthalmic disease. Trans Am Ophthalmol Soc. 1999; 97:451-64; discussion 464-9. Sieving PA, Yashar BM, Ayyagari R. PMID: 10703138.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    181. The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2458-65. Sugawara T, Sieving PA, Iuvone PM, Bush RA. PMID: 9804154.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCellsPHPublic Health
    182. Submicrovolt flicker electroretinogram: cycle-by-cycle recording of multiple harmonics with statistical estimation of measurement uncertainty. Invest Ophthalmol Vis Sci. 1998 Jul; 39(8):1462-9. Sieving PA, Arnold EB, Jamison J, Liepa A, Coats C. PMID: 9660495.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    183. Apparently new syndrome of sensorineural hearing loss, retinal pigment epithelium lesions, and discolored teeth. Am J Med Genet. 1998 Jan 06; 75(1):13-7. Innis JW, Sieving PA, McMillan P, Weatherly RA. PMID: 9450850.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    184. Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration. Neuron. 1997 Dec; 19(6):1329-36. Swain PK, Chen S, Wang QL, Affatigato LM, Coats CL, Brady KD, Fishman GA, Jacobson SG, Swaroop A, Stone E, Sieving PA, Zack DJ. PMID: 9427255.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    185. Spectrum of mutations in the RPGR gene that are identified in 20% of families with X-linked retinitis pigmentosa. Am J Hum Genet. 1997 Dec; 61(6):1287-92. Buraczynska M, Wu W, Fujita R, Buraczynska K, Phelps E, Andréasson S, Bennett J, Birch DG, Fishman GA, Hoffman DR, Inana G, Jacobson SG, Musarella MA, Sieving PA, Swaroop A. PMID: 9399904.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    186. Human bZIP transcription factor gene NRL: structure, genomic sequence, and fine linkage mapping at 14q11.2 and negative mutation analysis in patients with retinal degeneration. Genomics. 1997 Oct 15; 45(2):395-401. Farjo Q, Jackson A, Pieke-Dahl S, Scott K, Kimberling WJ, Sieving PA, Richards JE, Swaroop A. PMID: 9344665.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    187. Analysis of the RPGR gene in 11 pedigrees with the retinitis pigmentosa type 3 genotype: paucity of mutations in the coding region but splice defects in two families. Am J Hum Genet. 1997 Sep; 61(3):571-80. Fujita R, Buraczynska M, Gieser L, Wu W, Forsythe P, Abrahamson M, Jacobson SG, Sieving PA, Andréasson S, Swaroop A. PMID: 9326322.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    188. Increased phase lag of the fundamental harmonic component of the 30 Hz flicker ERG in Schubert-Bornschein complete type CSNB. Vision Res. 1997 Sep; 37(17):2471-5. Kim SH, Bush RA, Sieving PA. PMID: 9381682.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    189. Retinopathy induced in mice by targeted disruption of the rhodopsin gene. Nat Genet. 1997 Feb; 15(2):216-9. Humphries MM, Rancourt D, Farrar GJ, Kenna P, Hazel M, Bush RA, Sieving PA, Sheils DM, McNally N, Creighton P, Erven A, Boros A, Gulya K, Capecchi MR, Humphries P. PMID: 9020854.
      View in: PubMed   Mentions: 208     Fields:    Translation:AnimalsCells
    190. X-linked juvenile retinoschisis: localization between (DXS1195, DXS418) and AFM291wf5 on a single YAC. Hum Hered. 1996 Nov-Dec; 46(6):329-35. Pawar H, Bingham EL, Hiriyanna K, Segal M, Richards JE, Sieving PA. PMID: 8956029.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    191. Summation of rod and S cone signals at threshold in human observers. Vision Res. 1996 Sep; 36(17):2681-8. Naarendorp F, Rice KS, Sieving PA. PMID: 8917755.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    192. Linkage study of Best's vitelliform macular dystrophy (VMD2) in a large North American family. Hum Hered. 1996 Jul-Aug; 46(4):211-20. Hou YC, Richards JE, Bingham EL, Pawar H, Scott K, Segal M, Lunetta KL, Boehnke M, Sieving PA. PMID: 8807324.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    193. A recombination outside the BB deletion refines the location of the X linked retinitis pigmentosa locus RP3. Am J Hum Genet. 1996 Jul; 59(1):152-8. Fujita R, Bingham E, Forsythe P, McHenry C, Aita V, Navia BA, Dry K, Segal M, Devoto M, Bruns G, Wright AF, Ott J, Sieving PA, Swaroop A. PMID: 8659520.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    194. Inner retinal contributions to the primate photopic fast flicker electroretinogram. J Opt Soc Am A Opt Image Sci Vis. 1996 Mar; 13(3):557-65. Bush RA, Sieving PA. PMID: 8627412.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    195. Sorsby's fundus dystrophy in a family with a Ser-181-CVS mutation in the TIMP-3 gene: poor outcome after laser photocoagulation. Trans Am Ophthalmol Soc. 1996; 94:275-94; discussion 295-7. Sieving PA, Boskovich S, Bingham E, Pawar H. PMID: 8981701.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    196. A polymorphic trinucleotide repeat at DXS8170 in the critical region of X-linked retinitis pigmentosa locus RP3 at Xp21.1. Mol Vis. 1995 Dec 05; 1:3. Fujita R, Blumberg M, Anderson D, Forsythe P, McHenry C, Yan D, Yang-Feng TL, Sieving PA, Swaroop A. PMID: 9238081.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    197. Diagnostic issues with inherited retinal and macular dystrophies. Semin Ophthalmol. 1995 Dec; 10(4):279-94. Sieving PA. PMID: 10160215.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    198. Preservation of inner retinal responses in the aged Royal College of Surgeons rat. Evidence against glutamate excitotoxicity in photoreceptor degeneration. Invest Ophthalmol Vis Sci. 1995 Sep; 36(10):2054-62. Bush RA, Hawks KW, Sieving PA. PMID: 7657544.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    199. Refined genetic mapping of juvenile X-linked retinoschisis. Hum Hered. 1995 Jul-Aug; 45(4):206-10. Pawar H, Bingham EL, Lunetta KL, Segal M, Richards JE, Boehnke M, Sieving PA. PMID: 7558052.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    200. Disruption of conserved rhodopsin disulfide bond by Cys187Tyr mutation causes early and severe autosomal dominant retinitis pigmentosa. Ophthalmology. 1995 Apr; 102(4):669-77. Richards JE, Scott KM, Sieving PA. PMID: 7724183.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    201. Evidence for two sites of adaptation affecting the dark-adapted ERG of cats and primates. Vision Res. 1995 Feb; 35(3):435-42. Frishman LJ, Sieving PA. PMID: 7892737.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    202. Dark-light: model for nightblindness from the human rhodopsin Gly-90-->Asp mutation. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):880-4. Sieving PA, Richards JE, Naarendorp F, Bingham EL, Scott K, Alpern M. PMID: 7846071.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    203. Dinucleotide repeat polymorphism at the DXS977 locus. Hum Mol Genet. 1994 Jun; 3(6):1030. Yan D, Wong D, Zheng K, Thiselton D, Fujita R, Sieving PA, Bhattacharya SS, Yang-Feng TL, Richards JE, Swaroop A. PMID: 7951222.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    204. Push-pull model of the primate photopic electroretinogram: a role for hyperpolarizing neurons in shaping the b-wave. Vis Neurosci. 1994 May-Jun; 11(3):519-32. Sieving PA, Murayama K, Naarendorp F. PMID: 8038126.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    205. A proximal retinal component in the primate photopic ERG a-wave. Invest Ophthalmol Vis Sci. 1994 Feb; 35(2):635-45. Bush RA, Sieving PA. PMID: 8113014.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    206. 'Unilateral cone dystrophy': ERG changes implicate abnormal signaling by hyperpolarizing bipolar and/or horizontal cells. Trans Am Ophthalmol Soc. 1994; 92:459-71; discussion 471-4. Sieving PA. PMID: 7886877.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    207. Dopaminergic modulation of rod pathway signals does not affect the scotopic ERG of cat at dark-adapted threshold. J Neurophysiol. 1993 Oct; 70(4):1681-91. Naarendorp F, Hitchock PF, Sieving PA. PMID: 8283223.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    208. Identification of novel rhodopsin mutations responsible for retinitis pigmentosa: implications for the structure and function of rhodopsin. Am J Hum Genet. 1993 Jul; 53(1):80-9. Macke JP, Davenport CM, Jacobson SG, Hennessey JC, Gonzalez-Fernandez F, Conway BP, Heckenlively J, Palmer R, Maumenee IH, Sieving P. PMID: 8317502.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    209. Assessment of foveal cone photoreceptors in Stargardt's macular dystrophy using a small dot detection task. Vision Res. 1993 Jul; 33(11):1509-24. Geller AM, Sieving PA. PMID: 8351823.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    210. Photopic ON- and OFF-pathway abnormalities in retinal dystrophies. Trans Am Ophthalmol Soc. 1993; 91:701-73. Sieving PA. PMID: 8140708.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    211. Effect on grating identification of sampling with degenerate arrays. J Opt Soc Am A. 1992 Mar; 9(3):472-7. Geller AM, Sieving PA, Green DG. PMID: 1548555.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    212. Rhodopsin Thr58Arg mutation in a family with autosomal dominant retinitis pigmentosa. Ophthalmology. 1991 Dec; 98(12):1797-805. Richards JE, Kuo CY, Boehnke M, Sieving PA. PMID: 1775313.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    213. Fenestrated sheen macular dystrophy. Am J Ophthalmol. 1991 Jul 15; 112(1):1-7. Sneed SR, Sieving PA. PMID: 1882912.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    214. Pupillary and electroretinographic abnormalities in a family with neuronal intranuclear hyaline inclusion disease. Arch Ophthalmol. 1991 Mar; 109(3):373-8. Arrindell EL, Trobe JD, Sieving PA, Barnett JL. PMID: 1848426.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    215. The scotopic threshold response of the cat ERG is suppressed selectively by GABA and glycine. Vision Res. 1991; 31(1):1-15. Naarendorp F, Sieving PA. PMID: 2006543.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    216. Idiopathic photoreceptor dysfunction causes unexplained visual acuity loss in later adulthood. Ophthalmology. 1990 Dec; 97(12):1632-7. Rowe SE, Trobe JD, Sieving PA. PMID: 2087294.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    217. Linkage relationship of X-linked juvenile retinoschisis with Xp22.1-p22.3 probes. Am J Hum Genet. 1990 Oct; 47(4):616-21. Sieving PA, Bingham EL, Roth MS, Young MR, Boehnke M, Kuo CY, Ginsburg D. PMID: 1977307.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    218. Leber's congenital amaurosis with marbelized fundus and juvenile nephronophthisis. Am J Ophthalmol. 1989 Apr 15; 107(4):426-8. Ticho B, Sieving PA. PMID: 2929712.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    219. Aspartate separation of the scotopic threshold response (STR) from the photoreceptor a-wave of the cat and monkey ERG. Invest Ophthalmol Vis Sci. 1988 Nov; 29(11):1615-22. Wakabayashi K, Gieser J, Sieving PA. PMID: 3182196.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    220. Scotopic threshold response (STR) of the human electroretinogram. Invest Ophthalmol Vis Sci. 1988 Nov; 29(11):1608-14. Sieving PA, Nino C. PMID: 3182195.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    221. Foveal retinoschisis associated with senile retinoschisis in a woman. Am J Ophthalmol. 1988 Jul 15; 106(1):107-9. Han DP, Sieving PA, Johnson MW, Martonyi CL. PMID: 3394761.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    222. Contributions to the electroretinogram of currents originating in proximal retina. Vis Neurosci. 1988; 1(3):307-15. Frishman LJ, Sieving PA, Steinberg RH. PMID: 3154802.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    223. Proximal retinal contribution to the intraretinal 8-Hz pattern ERG of cat. J Neurophysiol. 1987 Jan; 57(1):104-20. Sieving PA, Steinberg RH. PMID: 3559667.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    224. M-wave of proximal retina in cat. J Neurophysiol. 1986 Oct; 56(4):1039-48. Sieving PA, Frishman LJ, Steinberg RH. PMID: 3783227.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    225. Scotopic threshold response of proximal retina in cat. J Neurophysiol. 1986 Oct; 56(4):1049-61. Sieving PA, Frishman LJ, Steinberg RH. PMID: 3783228.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    226. Electroretinographic findings in selected pedigrees with choroideremia. Am J Ophthalmol. 1986 Mar 15; 101(3):361-7. Sieving PA, Niffenegger JH, Berson EL. PMID: 3953730.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    227. Contribution from proximal retina to intraretinal pattern ERG: the M-wave. Invest Ophthalmol Vis Sci. 1985 Nov; 26(11):1642-7. Sieving PA, Steinberg RH. PMID: 4055298.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    228. Multiple evanescent white dot syndrome. I. Clinical findings. Arch Ophthalmol. 1984 May; 102(5):671-4. Jampol LM, Sieving PA, Pugh D, Fishman GA, Gilbert H. PMID: 6721749.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    229. Multiple evanescent white dot syndrome. II. Electrophysiology of the photoreceptors during retinal pigment epithelial disease. Arch Ophthalmol. 1984 May; 102(5):675-9. Sieving PA, Fishman GA, Jampol LM, Pugh D. PMID: 6721750.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    230. Acute macular neuroretinopathy: early receptor potential change suggests photoreceptor pathology. Br J Ophthalmol. 1984 Apr; 68(4):229-34. Sieving PA, Fishman GA, Salzano T, Rabb MF. PMID: 6704358.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    231. Early receptor potential measurements in human ocular siderosis. Arch Ophthalmol. 1983 Nov; 101(11):1716-20. Sieving PA, Fishman GA, Alexander KR, Goldberg MF. PMID: 6639427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    232. Calibration error in dark adaptometer. Arch Ophthalmol. 1978 Jun; 96(6):1082-3. Maggiano JM, Fishman GA, Evans LS, Sieving P, Goldbaum M. PMID: 655945.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    233. Corneal wick electrode for recording bright flash electroretinograms and early receptor potentials. Arch Ophthalmol. 1978 May; 96(5):899-900. Sieving PA, Fishman GA, Maggiano JM. PMID: 655931.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    234. Refractive errors of retinitis pigmentosa patients. Br J Ophthalmol. 1978 Mar; 62(3):163-7. Sieving PA, Fishman GA. PMID: 638108.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    Paul's Networks
    Concepts (711)
    Derived automatically from this person's publications.
    _
    Co-Authors (15)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _