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Niels Pedersen

TitlePROF EMERITUS(WOS)
InstitutionUniversity of California Davis
DepartmentVM: CTR COMPANION ANIMAL HLTH
Address213 CCAH
CA 95616
Phone530-752-7402
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Watanabe R, Eckstrand C, Liu H, Pedersen N. Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq. Vet Res. 2018 Aug 07; 49(1):81. PMID: 30086792.
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    2. Gandolfi B, Alhaddad H, Abdi M, Bach LH, Creighton EK, Davis BW, Decker JE, Dodman NH, Grahn JC, Grahn RA, Haase B, Haggstrom J, Hamilton MJ, Helps CR, Kurushima JD, Lohi H, Longeri M, Malik R, Meurs KM, Montague MJ, Mullikin JC, Murphy WJ, Nilson SM, Pedersen N, Peterson CB, Rusbridge C, Saif R, Shelton GD, Warren WC, Wasim M, Lyons LA. Author Correction: Applications and efficiencies of the first cat 63K DNA array. Sci Rep. 2018 Jun 04; 8(1):8746. PMID: 29867197.
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    3. Gandolfi B, Alhaddad H, Abdi M, Bach LH, Creighton EK, Davis BW, Decker JE, Dodman NH, Grahn JC, Grahn RA, Haase B, Haggstrom J, Hamilton MJ, Helps CR, Kurushima JD, Lohi H, Longeri M, Malik R, Meurs KM, Montague MJ, Mullikin JC, Murphy WJ, Nilson SM, Pedersen N, Peterson CB, Rusbridge C, Saif R, Shelton DG, Warren WC, Wasim M, Lyons LA. Applications and efficiencies of the first cat 63K DNA array. Sci Rep. 2018 May 04; 8(1):7024. PMID: 29728693.
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    4. Pedersen N, Shope B, Liu H. An autosomal recessive mutation in SCL24A4 causing enamel hypoplasia in Samoyed and its relationship to breed-wide genetic diversity. Canine Genet Epidemiol. 2017; 4:11. PMID: 29201383.
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    5. Pedersen N, Kim Y, Liu H, Galasiti Kankanamalage AC, Eckstrand C, Groutas WC, Bannasch M, Meadows JM, Chang KO. Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis. J Feline Med Surg. 2018 Apr; 20(4):378-392. PMID: 28901812.
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    6. Pedersen N, Dhanota JK, Liu H. Polymorphisms in ERAP1 and ERAP2 are shared by Caninae and segregate within and between random- and pure-breeds of dogs. Vet Immunol Immunopathol. 2016 Oct 15; 179:46-57. PMID: 27590425.
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    7. Safra N, Hitchens PL, Maverakis E, Mitra A, Korff C, Johnson E, Kol A, Bannasch MJ, Pedersen N, Bannasch DL. Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission. Vet Immunol Immunopathol. 2016 Oct 15; 179:32-5. PMID: 27590423.
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    8. Pedersen N, Pooch AS, Liu H. A genetic assessment of the English bulldog. Canine Genet Epidemiol. 2016; 3:6. PMID: 27478618; PMCID: PMC4965900.
    9. Kim Y, Liu H, Kankanamalage AC, Weerasekara S, Hua DH, Groutas WC, Chang KO, Pedersen N. Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor. PLoS Pathog. 2016 May; 12(5):e1005650. PMID: 27166862.
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    10. Kim Y, Liu H, Galasiti Kankanamalage AC, Weerasekara S, Hua DH, Groutas WC, Chang KO, Pedersen N. Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor. PLoS Pathog. 2016 Mar; 12(3):e1005531. PMID: 27027316; PMCID: PMC4814111.
    11. Pedersen N, Liu H, Durden M, Lyons LA. Natural resistance to experimental feline infectious peritonitis virus infection is decreased rather than increased by positive genetic selection. Vet Immunol Immunopathol. 2016 Mar; 171:17-20. PMID: 26964713.
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    12. Pedersen N, Liu H, Leonard A, Griffioen L. A search for genetic diversity among Italian Greyhounds from Continental Europe and the USA and the effect of inbreeding on susceptibility to autoimmune disease. Canine Genet Epidemiol. 2015; 2:17. PMID: 26526059; PMCID: PMC4628233.
    13. Pedersen N, Brucker L, Tessier NG, Liu H, Penedo MC, Hughes S, Oberbauer A, Sacks B. The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison's disease. Canine Genet Epidemiol. 2015; 2:14. PMID: 26401342; PMCID: PMC4579369.
    14. Fleischman DA, Chomel BB, Kasten RW, Stuckey MJ, Scarlet J, Liu H, Boulouis HJ, Haddad N, Pedersen N. Bartonella Infection among Cats Adopted from a San Francisco Shelter, Revisited. Appl Environ Microbiol. 2015 Sep; 81(18):6446-50. PMID: 26162871; PMCID: PMC4542261.
    15. Jones BR, Little S, Lyons LA, Malik R, Nicholas F, O'Brien DP, Pedersen N. Understanding genetics: why should vets care? J Feline Med Surg. 2015 Mar; 17(3):201-2. PMID: 25701859.
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    16. Pedersen N, Eckstrand C, Liu H, Leutenegger C, Murphy B. Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection. Vet Microbiol. 2015 Feb 25; 175(2-4):157-66. PMID: 25532961.
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    17. Pedersen N, Liu H, Gandolfi B, Lyons LA. The influence of age and genetics on natural resistance to experimentally induced feline infectious peritonitis. Vet Immunol Immunopathol. 2014 Nov 15; 162(1-2):33-40. PMID: 25265870.
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    18. Pedersen N. An update on feline infectious peritonitis: virology and immunopathogenesis. Vet J. 2014 Aug; 201(2):123-32. PMID: 24837550.
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    19. Pedersen N. An update on feline infectious peritonitis: diagnostics and therapeutics. Vet J. 2014 Aug; 201(2):133-41. PMID: 24857253.
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    20. Alhaddad H, Gandolfi B, Grahn RA, Rah HC, Peterson CB, Maggs DJ, Good KL, Pedersen N, Lyons LA. Genome-wide association and linkage analyses localize a progressive retinal atrophy locus in Persian cats. Mamm Genome. 2014 Aug; 25(7-8):354-62. PMID: 24777202; PMCID: PMC4105591.
    21. Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen N, North TW. Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV. PLoS One. 2014; 9(1):e86997. PMID: 24498008; PMCID: PMC3909041.
    22. Gandolfi B, Liu H, Griffioen L, Pedersen N. Simple recessive mutation in ENAM is associated with amelogenesis imperfecta in Italian Greyhounds. Anim Genet. 2013 Aug; 44(5):569-78. PMID: 23638899.
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    23. Golovko L, Lyons LA, Liu H, Sørensen A, Wehnert S, Pedersen N. Genetic susceptibility to feline infectious peritonitis in Birman cats. Virus Res. 2013 Jul; 175(1):58-63. PMID: 23619280; PMCID: PMC4342855.
    24. Sacks BN, Brown SK, Stephens D, Pedersen N, Wu JT, Berry O. Y chromosome analysis of dingoes and southeast asian village dogs suggests a neolithic continental expansion from Southeast Asia followed by multiple Austronesian dispersals. Mol Biol Evol. 2013 May; 30(5):1103-18. PMID: 23408799.
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    25. Massey J, Boag A, Short AD, Scholey RA, Henthorn PS, Littman MP, Husebye E, Catchpole B, Pedersen N, Mellersh CS, Ollier WE, Kennedy LJ. MHC class II association study in eight breeds of dog with hypoadrenocorticism. Immunogenetics. 2013 Apr; 65(4):291-7. PMID: 23358933.
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    26. Pedersen N, Liu H, Theilen G, Sacks B. The effects of dog breed development on genetic diversity and the relative influences of performance and conformation breeding. J Anim Breed Genet. 2013 Jun; 130(3):236-48. PMID: 23679949.
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    27. Pedersen N, Liu H, McLaughlin B, Sacks BN. Genetic characterization of healthy and sebaceous adenitis affected Standard Poodles from the United States and the United Kingdom. Tissue Antigens. 2012 Jul; 80(1):46-57. PMID: 22512808.
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    28. Pedersen N, Liu H, Scarlett J, Leutenegger CM, Golovko L, Kennedy H, Kamal FM. Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. Virus Res. 2012 Apr; 165(1):17-28. PMID: 22280883.
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    29. Brown SK, Pedersen N, Jafarishorijeh S, Bannasch DL, Ahrens KD, Wu JT, Okon M, Sacks BN. Phylogenetic distinctiveness of Middle Eastern and Southeast Asian village dog Y chromosomes illuminates dog origins. PLoS One. 2011; 6(12):e28496. PMID: 22194840; PMCID: PMC3237445.
    30. Pedersen N, Liu H, Greenfield DL, Echols LG. Multiple autoimmune diseases syndrome in Italian Greyhounds: preliminary studies of genome-wide diversity and possible associations within the dog leukocyte antigen (DLA) complex. Vet Immunol Immunopathol. 2012 Jan 15; 145(1-2):264-76. PMID: 22178273.
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    31. Pedersen N, Liu H, Millon L, Greer K. Dog leukocyte antigen class II-associated genetic risk testing for immune disorders of dogs: simplified approaches using Pug dog necrotizing meningoencephalitis as a model. J Vet Diagn Invest. 2011 Jan; 23(1):68-76. PMID: 21217030.
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    32. Bannasch D, Young A, Myers J, Truvé K, Dickinson P, Gregg J, Davis R, Bongcam-Rudloff E, Webster MT, Lindblad-Toh K, Pedersen N. Localization of canine brachycephaly using an across breed mapping approach. PLoS One. 2010 Mar 10; 5(3):e9632. PMID: 20224736; PMCID: PMC2835769.
    33. Pedersen N, Liu H, Dodd KA, Pesavento PA. Significance of coronavirus mutants in feces and diseased tissues of cats suffering from feline infectious peritonitis. Viruses. 2009 09; 1(2):166-84. PMID: 21994544; PMCID: PMC3185486.
    34. Pedersen N. A review of feline infectious peritonitis virus infection: 1963-2008. J Feline Med Surg. 2009 Apr; 11(4):225-58. PMID: 19254859.
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    35. Pedersen N, Allen CE, Lyons LA. Pathogenesis of feline enteric coronavirus infection. J Feline Med Surg. 2008 Dec; 10(6):529-41. PMID: 18538604.
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    36. Lipinski MJ, Froenicke L, Baysac KC, Billings NC, Leutenegger CM, Levy AM, Longeri M, Niini T, Ozpinar H, Slater MR, Pedersen N, Lyons LA. The ascent of cat breeds: genetic evaluations of breeds and worldwide random-bred populations. Genomics. 2008 Jan; 91(1):12-21. PMID: 18060738; PMCID: PMC2267438.
    37. Shen X, Leutenegger CM, Stefano Cole K, Pedersen N, Sparger EE. A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens. J Gen Virol. 2007 Oct; 88(Pt 10):2793-9. PMID: 17872533.
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    38. Bighignoli B, Niini T, Grahn RA, Pedersen N, Millon LV, Polli M, Longeri M, Lyons LA. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) mutations associated with the domestic cat AB blood group. BMC Genet. 2007 Jun 06; 8:27. PMID: 17553163; PMCID: PMC1913925.
    39. Van Rompay KK, Johnson JA, Blackwood EJ, Singh RP, Lipscomb J, Matthews TB, Marthas ML, Pedersen N, Bischofberger N, Heneine W, North TW. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. Retrovirology. 2007 Apr 06; 4:25. PMID: 17417971; PMCID: PMC1852805.
    40. Foley J, Hurley K, Pesavento PA, Poland A, Pedersen N. Virulent systemic feline calicivirus infection: local cytokine modulation and contribution of viral mutants. J Feline Med Surg. 2006 Feb; 8(1):55-61. PMID: 16213763.
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    41. Kummrow M, Meli ML, Haessig M, Goenczi E, Poland A, Pedersen N, Hofmann-Lehmann R, Lutz H. Feline coronavirus serotypes 1 and 2: seroprevalence and association with disease in Switzerland. Clin Diagn Lab Immunol. 2005 Oct; 12(10):1209-15. PMID: 16210485; PMCID: PMC1247821.
    42. North TW, Van Rompay KK, Higgins J, Matthews TB, Wadford DA, Pedersen N, Schinazi RF. Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. J Virol. 2005 Jun; 79(12):7349-54. PMID: 15919889; PMCID: PMC1143671.
    43. Pedersen N. [Feline calicivirus infection]. Tijdschr Diergeneeskd. 2005 May 01; 130(9):275-7. PMID: 15906827.
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    44. Louwerens M, London CA, Pedersen N, Lyons LA. Feline lymphoma in the post-feline leukemia virus era. J Vet Intern Med. 2005 May-Jun; 19(3):329-35. PMID: 15954547.
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    45. Bannasch DL, Bannasch MJ, Ryun JR, Famula TR, Pedersen N. Y chromosome haplotype analysis in purebred dogs. Mamm Genome. 2005 Apr; 16(4):273-80. PMID: 15965788.
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    46. Irion DN, Schaffer AL, Grant S, Wilton AN, Pedersen N. Genetic variation analysis of the Bali street dog using microsatellites. BMC Genet. 2005 Feb 08; 6:6. PMID: 15701179; PMCID: PMC549630.
    47. Hofman MJ, Higgins J, Matthews TB, Pedersen N, Tan C, Schinazi RF, North TW. Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2004 Sep; 48(9):3483-90. PMID: 15328115; PMCID: PMC514752.
    48. Neff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen N. Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proc Natl Acad Sci U S A. 2004 Aug 10; 101(32):11725-30. PMID: 15289602; PMCID: PMC511012.
    49. Morris KV, Grahn RA, Looney DJ, Pedersen N. Characterization of a mobilization-competent simian immunodeficiency virus (SIV) vector containing a ribozyme against SIV polymerase. J Gen Virol. 2004 Jun; 85(Pt 6):1489-96. PMID: 15166433.
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    50. Van Rompay KK, Brignolo LL, Meyer DJ, Jerome C, Tarara R, Spinner A, Hamilton M, Hirst LL, Bennett DR, Canfield DR, Dearman TG, Von Morgenland W, Allen PC, Valverde C, Castillo AB, Martin RB, Samii VF, Bendele R, Desjardins J, Marthas ML, Pedersen N, Bischofberger N. Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques. Antimicrob Agents Chemother. 2004 May; 48(5):1469-87. PMID: 15105094; PMCID: PMC400569.
    51. Addie DD, Paltrinieri S, Pedersen N. Recommendations from workshops of the second international feline coronavirus/feline infectious peritonitis symposium. J Feline Med Surg. 2004 Apr; 6(2):125-30. PMID: 15123158.
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    52. Hurley KE, Pesavento PA, Pedersen N, Poland AM, Wilson E, Foley JE. An outbreak of virulent systemic feline calicivirus disease. J Am Vet Med Assoc. 2004 Jan 15; 224(2):241-9. PMID: 14736069.
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    53. Dean GA, Olivry T, Stanton C, Pedersen N. In vivo cytokine response to experimental feline infectious peritonitis virus infection. Vet Microbiol. 2003 Dec 02; 97(1-2):1-12. PMID: 14637034.
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    54. Preiss BS, Kerndrup GB, Schmidt KG, Sørensen AG, Clausen NA, Gadeberg OV, Mourits-Andersen T, Pedersen N. Cytogenetic findings in adult de novo acute myeloid leukaemia. A population-based study of 303/337 patients. Br J Haematol. 2003 Oct; 123(2):219-34. PMID: 14531903.
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    55. Pedersen N, North TW, Rigg R, Reading C, Higgins J, Leutenegger C, Henderson GL. 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression. Vet Immunol Immunopathol. 2003 Aug 15; 94(3-4):133-48. PMID: 12909410.
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    56. Morris KV, Higgins J, Shen X, Stine JT, Pedersen N. The effects of HHV-8 vMIP-II on SIVmac251 infection and replication competent and incompetent SIVmac239Delta3 vectors. Virus Res. 2003 Aug; 94(2):103-12. PMID: 12902039.
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    57. Yamamoto K, Chomel BB, Kasten RW, Hew CM, Weber DK, Lee WI, Koehler JE, Pedersen N. Infection and re-infection of domestic cats with various Bartonella species or types: B. henselae type I is protective against heterologous challenge with B. henselae type II. Vet Microbiol. 2003 Mar 20; 92(1-2):73-86. PMID: 12488072.
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    58. Murry JP, Higgins J, Matthews TB, Huang VY, Van Rompay KK, Pedersen N, North TW. Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine. J Virol. 2003 Jan; 77(2):1120-30. PMID: 12502828; PMCID: PMC140811.
    59. George JW, Rideout BA, Griffey SM, Pedersen N. Effect of preexisting FeLV infection or FeLV and feline immunodeficiency virus coinfection on pathogenicity of the small variant of Haemobartonella felis in cats. Am J Vet Res. 2002 Aug; 63(8):1172-8. PMID: 12171173.
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    60. Van Rompay KK, Matthews TB, Higgins J, Canfield DR, Tarara RP, Wainberg MA, Schinazi RF, Pedersen N, North TW. Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. J Virol. 2002 Jun; 76(12):6083-92. PMID: 12021341; PMCID: PMC136201.
    61. Pedersen N, Elliott JB, Glasgow A, Poland A, Keel K. An isolated epizootic of hemorrhagic-like fever in cats caused by a novel and highly virulent strain of feline calicivirus. Vet Microbiol. 2000 May 11; 73(4):281-300. PMID: 10781727.
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    62. Pedersen N, Dean GA, Bernales J, Sukura A, Higgins J. Listeria monocytogenes and Serratia marcescens infections as models for Th1/Th2 immunity in laboratory cats. Vet Immunol Immunopathol. 1998 May 15; 63(1-2):83-103. PMID: 9656444.
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