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Barbara Shacklett, PhD

Title(s)Professor, Medical Microbiology and Immunology
SchoolUniversity of California, Davis
AddressTupper Hall
CA 95616
Phone530-752-6785
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    1. Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosa of HIV-infected women. Am J Reprod Immunol. 2020 Jul; 84(1):e13246. Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. PMID: 32301548.
      View in: PubMed   Mentions:    Fields:    
    2. Receptive anal sex contributes substantially to heterosexually-acquired HIV infections among at-risk women in Twenty US Cities: results from a modelling analysis. Am J Reprod Immunol. 2020 May 08; e13263. Elmes J, Silhol R, Hess KL, Gedge LM, Nordsletten A, Staunton R, Anton P, Shacklett B, McGowan I, Dang Q, Adimora AA, Dimitrov DT, Aral S, Handanagic S, Paz-Bailey G, Boily MC. PMID: 32384198.
      View in: PubMed   Mentions:    Fields:    
    3. Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. Curr HIV/AIDS Rep. 2020 Apr; 17(2):109-117. Shacklett BL, Ferre AL, Kiniry BE. PMID: 32052270.
      View in: PubMed   Mentions:    Fields:    
    4. What Proportion of Female Sex Workers Practise anal Intercourse and How Frequently? A Systematic Review and Meta-analysis. AIDS Behav. 2020 Mar; 24(3):697-713. Owen BN, Baggaley RF, Elmes J, Harvey A, Shubber Z, Butler AR, Silhol R, Anton P, Shacklett B, van der Straten A, Boily MC. PMID: 30953304.
      View in: PubMed   Mentions: 2     Fields:    
    5. Increases in HIV Incidence Following Receptive Anal Intercourse Among Women: A Systematic Review and Meta-analysis. AIDS Behav. 2020 Mar; 24(3):667-681. Stannah J, Silhol R, Elmes J, Owen B, Shacklett BL, Anton P, McGowan I, van der Straten A, Dimitrov D, Baggaley RF, Boily MC. PMID: 31486008.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection. Nat Commun. 2020 01 14; 11(1):272. Lal KG, Kim D, Costanzo MC, Creegan M, Leeansyah E, Dias J, Paquin-Proulx D, Eller LA, Schuetz A, Phuang-Ngern Y, Krebs SJ, Slike BM, Kibuuka H, Maganga L, Nitayaphan S, Kosgei J, Sacdalan C, Ananworanich J, Bolton DL, Michael NL, Shacklett BL, Robb ML, Eller MA, Sandberg JK. PMID: 31937782.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. Effects of the levonorgestrel-containing intrauterine device, copper intrauterine device, and levonorgestrel-containing oral contraceptive on susceptibility of immune cells from cervix, endometrium and blood to HIV-1 fusion measured ex vivo. PLoS One. 2019; 14(8):e0221181. Cavrois M, Hilton JF, Roan NR, Takeda M, Seidman D, Averbach S, Chang E, Raman N, Greenblatt R, Shacklett BL, Smith-McCune K. PMID: 31437197.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. HIV-1 is rarely detected in blood and colon myeloid cells during viral-suppressive antiretroviral therapy. AIDS. 2019 07 01; 33(8):1293-1306. Cattin A, Wiche Salinas TR, Gosselin A, Planas D, Shacklett B, Cohen EA, Ghali MP, Routy JP, Ancuta P. PMID: 30870200.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. HIV Research for Prevention 2018: From Research to Impact Conference Summary and Highlights. AIDS Res Hum Retroviruses. 2019 07; 35(7):598-607. Shacklett BL, Blanco J, Hightow-Weidman L, Mgodi N, Alcamí J, Buchbinder S, Chirenje M, Dabee S, Diallo M, Dumchev K, Herrera C, Levy ME, Martin Gayo E, Makoah NA, Mitchell KM, Mugwanya K, Reddy K, Rodríguez ML, Rodriguez-Garcia M, Shover CL, Shrivastava T, Tomaras G, Van Diepen M, Walia M, Warren M, Manrique A, Thyagarajan B, Torri T. PMID: 31007035.
      View in: PubMed   Mentions: 1     Fields:    
    10. Tissue issues: mucosal T-cell responses in HIV-1 infection. Curr Opin HIV AIDS. 2019 03; 14(2):100-107. Shacklett BL, Ferre AL, Kiniry BE. PMID: 30601239.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Mucosal Immunity in HIV/SIV Infection: T Cells, B Cells and Beyond. Curr Immunol Rev. 2019; 15(1):63-75. Shacklett BL. PMID: 31327960.
      View in: PubMed   Mentions:
    12. Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis. Am J Reprod Immunol. 2018 11; 80(5):e13039. Baggaley RF, Owen BN, Silhol R, Elmes J, Anton P, McGowan I, van der Straten A, Shacklett B, Dang Q, Swann EM, Bolton DL, Boily MC. PMID: 30175479.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Cryopreservation of human mucosal tissues. PLoS One. 2018; 13(7):e0200653. Hughes SM, Ferre AL, Yandura SE, Shetler C, Baker CAR, Calienes F, Levy CN, Astronomo RD, Shu Z, Lentz GM, Fialkow M, Kirby AC, McElrath MJ, Sinclair E, Rohan LC, Anderson PL, Shacklett BL, Dezzutti CS, Gao D, Hladik F. PMID: 30059507.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. J Immunol. 2018 03 01; 200(5):1876-1888. Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 29352005.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection. Mucosal Immunol. 2018 05; 11(3):909-920. Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL. PMID: 29139476.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights. AIDS Res Hum Retroviruses. 2017 08; 33(8):749-759. Shacklett BL, Derdeyn CA, Folayan MO, Landovitz RJ, Anthony C, Behrens AJ, Hope TJ, Landais E, Leal L, Marrazzo JM, Morris L, Mugo N, Ngure K, Noseda V, Ranasinghe S, Tully DC, Voronin Y, Warren M, Wibmer CK, Xie IY, Scarlatti G, Thyagarajan B. PMID: 28649869.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    17. Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques. PLoS One. 2017; 12(1):e0170154. Chang WL, Gonzalez DF, Kieu HT, Castillo LD, Messaoudi I, Shen X, Tomaras GD, Shacklett BL, Barry PA, Sparger EE. PMID: 28095513.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. How common and frequent is heterosexual anal intercourse among South Africans? A systematic review and meta-analysis. J Int AIDS Soc. 2017 01 12; 19(1):21162. Owen BN, Elmes J, Silhol R, Dang Q, McGowan I, Shacklett B, Swann EM, van der Straten A, Baggaley RF, Boily MC. PMID: 28364565.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility. Mucosal Immunol. 2017 09; 10(5):1270-1278. Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL. PMID: 28051087.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy. AIDS. 2017 01 02; 31(1):35-48. Gosselin A, Wiche Salinas TR, Planas D, Wacleche VS, Zhang Y, Fromentin R, Chomont N, Cohen ÉA, Shacklett B, Mehraj V, Ghali MP, Routy JP, Ancuta P. PMID: 27835617.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    21. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017 07; 10(4):1008-1020. Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 27827375.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    22. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. PMID: 27401588.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    23. Cryopreservation of Human Mucosal Leukocytes. PLoS One. 2016; 11(5):e0156293. Hughes SM, Shu Z, Levy CN, Ferre AL, Hartig H, Fang C, Lentz G, Fialkow M, Kirby AC, Adams Waldorf KM, Veazey RS, Germann A, von Briesen H, McElrath MJ, Dezzutti CS, Sinclair E, Baker CA, Shacklett BL, Gao D, Hladik F. PMID: 27232996.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    24. Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS. PLoS One. 2016; 11(5):e0155629. Deere JD, Chang WL, Castillo LD, Schmidt KA, Kieu HT, Renzette N, Kowalik T, Barthold SW, Shacklett BL, Barry PA, Sparger EE. PMID: 27182601.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    25. Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers. AIDS Res Hum Retroviruses. 2016 08; 32(8):791-800. Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin BE, Ferre AL, Gillespie GM, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich SS, Shacklett BL. PMID: 27019338.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. PMID: 26177352.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    27. Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection. PLoS One. 2014; 9(12):e116081. Peterson J, Gisslen M, Zetterberg H, Fuchs D, Shacklett BL, Hagberg L, Yiannoutsos CT, Spudich SS, Price RW. PMID: 25541953.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    28. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. PLoS Pathog. 2014 May; 10(5):e1004078. Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. PMID: 24831517.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansCells
    29. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol. 2014 Feb; 71(2):95-108. Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. PMID: 24313954.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    30. Will loss of your MAITs weaken your HAART [corrected]? AIDS. 2013 10 23; 27(16):2501-4. Sandberg JK, Dias J, Shacklett BL, Leeansyah E. PMID: 23595154.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    31. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog. 2013; 9(10):e1003691. Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. PMID: 24130489.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCellsCTClinical Trials
    32. Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers. AIDS. 2013 Apr 24; 27(7):1145-9. Dahl V, Peterson J, Spudich S, Lee E, Shacklett BL, Price RW, Palmer S. PMID: 23211774.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    33. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 2013 Jun 06; 121(23):4635-46. Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, Palmer S, Lederman MM, Deeks SG. PMID: 23589670.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    34. Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa. AIDS. 2013 Mar 27; 27(6):867-77. Hayes TL, Asmuth DM, Critchfield JW, Knight TH, McLaughlin BE, Yotter T, McConnell DH, Garcia JC, Pollard RB, Shacklett BL. PMID: 23262500.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    35. Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood. 2013 Feb 14; 121(7):1124-35. Leeansyah E, Ganesh A, Quigley MF, Sönnerborg A, Andersson J, Hunt PW, Somsouk M, Deeks SG, Martin JN, Moll M, Shacklett BL, Sandberg JK. PMID: 23243281.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    36. Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation. AIDS Res Hum Retroviruses. 2013 Jan; 29(1):172-7. Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. PMID: 22998457.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    37. Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection. BMC Complement Altern Med. 2012 Jun 29; 12:84. Schunter M, Chu H, Hayes TL, McConnell D, Crawford SS, Luciw PA, Bengmark S, Asmuth DM, Brown J, Bevins CL, Shacklett BL, Critchfield JW. PMID: 22747752.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    38. Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells. AIDS. 2012 Jan 28; 26(3):263-73. Presicce P, Shaw JM, Miller CJ, Shacklett BL, Chougnet CA. PMID: 22095196.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    39. T Cell Responses During Human Immunodeficiency Virus (HIV)-1 Infection. . 2012 Jan 1; 141-169. Claire A. Chougnet, Barbara L. Shacklett. .
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    40. Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. J Virol. 2011 Nov; 85(21):11422-34. Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. PMID: 21880771.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    41. Mucosal immunity in HIV controllers: the right place at the right time. Curr Opin HIV AIDS. 2011 May; 6(3):202-7. Shacklett BL, Ferre AL. PMID: 21399497.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. J Infect Dis. 2011 Apr 01; 203(7):960-8. Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG. PMID: 21402547.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    43. Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications. Am J Reprod Immunol. 2011 Mar; 65(3):230-41. Shacklett BL, Greenblatt RM. PMID: 21223420.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    44. HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. J Virol. 2010 Nov; 84(21):11020-9. Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20719952.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    45. Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers. J Virol. 2010 Oct; 84(19):10354-65. Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20668079.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    46. Immune responses to HIV and SIV in mucosal tissues: 'location, location, location'. Curr Opin HIV AIDS. 2010 Mar; 5(2):128-34. Shacklett BL. PMID: 20543589.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. HIV Infection and Gut Mucosal Immune Function: Updates on Pathogenesis with Implications for Management and Intervention. Curr Infect Dis Rep. 2010 Jan; 12(1):19-27. Shacklett BL, Anton PA. PMID: 20174448.
      View in: PubMed   Mentions:
    48. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. J Virol. 2010 Mar; 84(6):2913-22. North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. PMID: 20032180.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    49. Cell-mediated immunity to HIV in the female reproductive tract. J Reprod Immunol. 2009 Dec; 83(1-2):190-5. Shacklett BL. PMID: 19857902.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    50. Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251. Virology. 2009 Mar 30; 386(1):109-21. Dubie RA, Maksaereekul S, Shacklett BL, Lemongello D, Cole KS, Villinger F, Blozis SA, Luciw PA, Sparger EE. PMID: 19193388.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    51. Quantifying HIV-1-specific CD8 (+) T-cell responses using ELISPOT and cytokine flow cytometry. Methods Mol Biol. 2009; 485:359-74. Shacklett BL, Critchfield JW, Lemongello D. PMID: 19020837.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    52. Mucosal T-cell responses to HIV: responding at the front lines. J Intern Med. 2009 Jan; 265(1):58-66. Shacklett BL, Critchfield JW, Ferre AL, Hayes TL. PMID: 19093960.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    53. Isolating mucosal lymphocytes from biopsy tissue for cellular immunology assays. Methods Mol Biol. 2009; 485:347-56. Shacklett BL, Critchfield JW, Lemongello D. PMID: 19020836.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    54. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood. 2009 Apr 23; 113(17):3978-89. Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 19109229.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    55. Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. PLoS One. 2008; 3(10):e3577. Critchfield JW, Young DH, Hayes TL, Braun JV, Garcia JC, Pollard RB, Shacklett BL. PMID: 18974782.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    56. Mucosal immunity to HIV: a review of recent literature. Curr Opin HIV AIDS. 2008 Sep; 3(5):541-7. Shacklett BL. PMID: 19373019.
      View in: PubMed   Mentions: 9     Fields:    
    57. Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry A. 2008 May; 73(5):411-20. McLaughlin BE, Baumgarth N, Bigos M, Roederer M, De Rosa SC, Altman JD, Nixon DF, Ottinger J, Li J, Beckett L, Shacklett BL, Evans TG, Asmuth DM. PMID: 18383309.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    58. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol. 2008 Jun; 82(11):5398-407. Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. PMID: 18353945.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    59. Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine. Virology. 2008 May 10; 374(2):261-72. Sparger EE, Dubie RA, Shacklett BL, Cole KS, Chang WL, Luciw PA. PMID: 18261756.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    60. Can the new humanized mouse model give HIV research a boost. PLoS Med. 2008 Jan 15; 5(1):e13. Shacklett BL. PMID: 18198940.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    61. Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection. J Virol. 2007 Jun; 81(11):5460-71. Critchfield JW, Lemongello D, Walker DH, Garcia JC, Asmuth DM, Pollard RB, Shacklett BL. PMID: 17344302.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    62. Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection. J Virol. 2006 Aug; 80(16):8236-47. Guadalupe M, Sankaran S, George MD, Reay E, Verhoeven D, Shacklett BL, Flamm J, Wegelin J, Prindiville T, Dandekar S. PMID: 16873279.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCells
    63. Understanding the "lucky few": The conundrum of HIV-exposed, seronegative individuals. Current Infectious Disease Reports. 2006 Jun 1; 8(3):248-253. Barbara L. Shacklett. .
      View in: Publisher Site   Mentions:
    64. Detection of macaque perforin expression and release by flow cytometry, immunohistochemistry, ELISA, and ELISpot. J Immunol Methods. 2006 May 30; 312(1-2):45-53. Zuber B, Quigley MF, Critchfield JW, Shacklett BL, Abel K, Miller CJ, Mörner A, Paulie S, Ahlborg N, Sandberg JK. PMID: 16647080.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    65. Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection. J Virol. 2006 Mar; 80(6):3083-7. Quigley MF, Abel K, Zuber B, Miller CJ, Sandberg JK, Shacklett BL. PMID: 16501118.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    66. Understanding the "lucky few": the conundrum of HIV-exposed, seronegative individuals. Curr HIV/AIDS Rep. 2006 Feb; 3(1):26-31. Shacklett BL. PMID: 16522256.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    67. Seroconversion following nonoccupational postexposure prophylaxis against HIV. Clin Infect Dis. 2005 Nov 15; 41(10):1507-13. Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN. PMID: 16231265.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    68. Multidrug-resistant, dual-tropic HIV-1 and rapid progression. Lancet. 2005 Jun 4-10; 365(9475):1924-5. Nixon DF, Deeks SG, Shacklett BL, Karlsson AC. PMID: 15936414.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    69. Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection. J Immunol. 2004 Jul 01; 173(1):641-8. Shacklett BL, Cox CA, Quigley MF, Kreis C, Stollman NH, Jacobson MA, Andersson J, Sandberg JK, Nixon DF. PMID: 15210827.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    70. Increased adhesion molecule and chemokine receptor expression on CD8+ T cells trafficking to cerebrospinal fluid in HIV-1 infection. J Infect Dis. 2004 Jun 15; 189(12):2202-12. Shacklett BL, Cox CA, Wilkens DT, Karl Karlsson R, Nilsson A, Nixon DF, Price RW. PMID: 15181567.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    71. Poorly soluble peptides can mimic authentic ELISPOT responses. J Immunol Methods. 2004 Feb 01; 285(1):89-92. Karlsson RK, Jennes W, Page-Shafer K, Nixon DF, Shacklett BL. PMID: 14871537.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    72. Limited magnitude and breadth in the HLA-A2-restricted CD8 T-Cell response to Nef in children with vertically acquired HIV-1 infection. Scand J Immunol. 2004 Jan; 59(1):109-14. Chandwani R, Jordan KA, Shacklett BL, Papasavvas E, Montaner LJ, Rosenberg MG, Nixon DF, Sandberg JK. PMID: 14723629.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    73. Optimization of methods to assess human mucosal T-cell responses to HIV infection. J Immunol Methods. 2003 Aug; 279(1-2):17-31. Shacklett BL, Yang O, Hausner MA, Elliott J, Hultin L, Price C, Fuerst M, Matud J, Hultin P, Cox C, Ibarrondo J, Wong JT, Nixon DF, Anton PA, Jamieson BD. PMID: 12969544.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    74. Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. J Virol. 2003 May; 77(10):5621-31. Shacklett BL, Cox CA, Sandberg JK, Stollman NH, Jacobson MA, Nixon DF. PMID: 12719554.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    75. Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay. J Immunol Methods. 2002 Dec 01; 270(1):99-108. Jennes W, Kestens L, Nixon DF, Shacklett BL. PMID: 12379342.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    76. Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. J Virol. 2002 Nov; 76(22):11365-78. Shacklett BL, Shaw KE, Adamson LA, Wilkens DT, Cox CA, Montefiori DC, Gardner MB, Sonigo P, Luciw PA. PMID: 12388697.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCellsPHPublic Health
    77. Beyond 51Cr release: New methods for assessing HIV-1-specific CD8+ T cell responses in peripheral blood and mucosal tissues. Clin Exp Immunol. 2002 Nov; 130(2):172-82. Shacklett BL. PMID: 12390303.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    78. Boosting of SIV-specific T cell responses in rhesus macaques that resist repeated intravaginal challenge with SIVmac251. AIDS Res Hum Retroviruses. 2002 Sep 20; 18(14):1081-8. Shacklett BL, Ling B, Veazey RS, Luckay A, Moretto WJ, Wilkens DT, Hu J, Israel ZR, Nixon DF, Marx PA. PMID: 12396459.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    79. Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women. AIDS Res Hum Retroviruses. 2002 Jul 20; 18(11):805-15. Shacklett BL, Means RE, Larsson M, Wilkens DT, Beadle TJ, Merritt MJ, Bhardwaj N, Palumbo PE, Skurnick JH, Louria DB, Nixon DF. PMID: 12167272.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    80. Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells. AIDS. 2002 Jan 25; 16(2):171-80. Larsson M, Wilkens DT, Fonteneau JF, Beadle TJ, Merritt MJ, Kost RG, Haslett PA, Cu-Uvin S, Bhardwaj N, Nixon DF, Shacklett BL. PMID: 11807300.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    81. Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure. J Infect Dis. 2002 Feb 15; 185(4):428-38. Skurnick JH, Palumbo P, DeVico A, Shacklett BL, Valentine FT, Merges M, Kamin-Lewis R, Mestecky J, Denny T, Lewis GK, Lloyd J, Praschunus R, Baker A, Nixon DF, Stranford S, Gallo R, Vermund SH, Louria DB. PMID: 11865394.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    82. Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19. J Virol. 2001 Jan; 75(1):540-3. Tolfvenstam T, Oxenius A, Price DA, Shacklett BL, Spiegel HM, Hedman K, Norbeck O, Levi M, Olsen K, Kantzanou M, Nixon DF, Broliden K, Klenerman P. PMID: 11119624.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    83. Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface. AIDS. 2000 Sep 08; 14(13):1911-5. Shacklett BL, Cu-Uvin S, Beadle TJ, Pace CA, Fast NM, Donahue SM, Caliendo AM, Flanigan TP, Carpenter CC, Nixon DF. PMID: 10997394.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    84. Isolation of cytomegalovirus-specific cytotoxic T-lymphocytes from gut-associated lymphoid tissue (GALT) of HIV type 1-infected subjects. AIDS Res Hum Retroviruses. 2000 Aug 10; 16(12):1157-62. Shacklett BL, Beadle TJ, Pacheco PA, Grendell JH, Haslett PA, King AS, Ogg GS, Basuk PM, Nixon DF. PMID: 10954891.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    85. The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques. J Virol. 2000 Jul; 74(13):5836-44. Shacklett BL, Weber CJ, Shaw KE, Keddie EM, Gardner MB, Sonigo P, Luciw PA. PMID: 10846063.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    86. Characterization of HIV-1-specific cytotoxic T lymphocytes expressing the mucosal lymphocyte integrin CD103 in rectal and duodenal lymphoid tissue of HIV-1-infected subjects. Virology. 2000 May 10; 270(2):317-27. Shacklett BL, Beadle TJ, Pacheco PA, Grendell JH, Haslett PA, King AS, Ogg GS, Basuk PM, Nixon DF. PMID: 10792991.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    87. Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins. J Virol. 1999 Feb; 73(2):1350-61. Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R. PMID: 9882340.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    88. Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis. Virology. 1998 Dec 05; 252(1):9-16. Luciw PA, Shaw KE, Shacklett BL, Marthas ML. PMID: 9875311.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    89. Features of the SIVmac transmembrane glycoprotein cytoplasmic domain that are important for Env functions. AIDS Res Hum Retroviruses. 1998 Mar 20; 14(5):373-83. Shacklett BL, Denesvre C, Boson B, Sonigo P. PMID: 9546796.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    90. The rhesus macaque CCR3 chemokine receptor is a cell entry cofactor for HIV-2, but not for HIV-1. Virology. 1998 Jan 20; 240(2):213-20. Sol N, Tréboute C, Gomas E, Ferchal F, Shacklett B, Alizon M. PMID: 9454694.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    91. Analysis of the vif gene of feline immunodeficiency virus. Virology. 1994 Nov 01; 204(2):860-7. Shacklett BL, Luciw PA. PMID: 7941360.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    92. Antiviral studies of feline infectious peritonitis virus in vitro. Vet Rec. 1994 Aug 20; 135(8):177-9. Barlough JE, Shacklett BL. PMID: 7992474.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    93. Identification of the Rev transactivation and Rev-responsive elements of feline immunodeficiency virus. J Virol. 1992 Sep; 66(9):5464-71. Phillips TR, Lamont C, Konings DA, Shacklett BL, Hamson CA, Luciw PA, Elder JH. PMID: 1323707.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    94. Regulation of gene expression directed by the long terminal repeat of the feline immunodeficiency virus. Virology. 1992 Mar; 187(1):165-77. Sparger EE, Shacklett BL, Renshaw-Gegg L, Barry PA, Pedersen NC, Elder JH, Luciw PA. PMID: 1310554.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
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