Peter A Barry

InstitutionUniversity of California Davis
DepartmentPathology and Laboratory Medicine
AddressDavis Campus
CA 95616
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    Collapse Research 
    Collapse Research Activities and Funding
    Role of reservoir composition and T cell immunity in HIV rebound kinetics
    NIH/NIAID P01AI131568Jul 19, 2017 - Jun 30, 2022
    Role: Co-Principal Investigator
    CMV-vectored Vaccine Approaches to Induce Protective Antibodies to HIV-1 Env
    NIH/NIAID R21AI134618Jun 26, 2017 - May 31, 2019
    Role: Principal Investigator
    Leveraging Established Fetal Primate Models to Expedite ZIKV Investigations
    NIH R21OD023716Aug 1, 2016 - Jul 31, 2018
    Role: Co-Principal Investigator
    Impact of chronic viral infections and altered microbiota on HIV vaccine efficacy
    NIH/NIAID R56AI120739Jun 18, 2015 - May 31, 2016
    Role: Co-Principal Investigator
    HCMV Vaccine produced from BAC-MVA that Blocks Epithelial and Fibroblast Entry
    NIH/NIAID R01AI103960May 15, 2013 - Apr 30, 2017
    Role: Co-Principal Investigator
    Vaccine-mediated Targeting of Viral IL10 to Control HCMV Shedding and Reinfection
    NIH/NIAID R01AI097629Dec 1, 2011 - Nov 30, 2016
    Role: Principal Investigator
    Attenuated RhCMV Delta 10 SIV Oral Vaccine Vectors Encoding TLR5 Ligand Sequences
    NIH/NIDCR R01DE021273Dec 1, 2010 - Nov 30, 2015
    Role: Co-Principal Investigator
    Development and Immunogenicity of Attenuated RhCMVdelta10 Vaccine Vectors
    NIH/NIAID R21AI088471Jun 15, 2010 - May 31, 2013
    Role: Co-Principal Investigator
    Evolution and Emergence of Simian Retroviruses in South Asia
    NIH/NIAID R01AI078229Aug 1, 2008 - Jul 31, 2013
    Role: Co-Principal Investigator
    Evaluation of Protective CMV Vaccines in Rhesus Macaques
    NIH/NIAID R01AI063356Jan 1, 2005 - Jan 31, 2016
    Role: Principal Investigator
    Post-Exposure Vaccination for HCMV Infection
    NIH/NIAID R03AI053208Sep 20, 2002 - Sep 30, 2005
    Role: Principal Investigator
    Prevention of Primary HCMV Infection by Vaccinating against HCMV-Encoded IL-10
    NIH/NIAID R01AI049342Apr 1, 2001 - Jan 31, 2018
    Role: Principal Investigator
    Prevention of Primary HCMV Infection by Vaccinating Against HCMV-Encoded IL-10
    NIH/NIAID R56AI049342Apr 1, 2001 - Jan 31, 2013
    Role: Principal Investigator
    NIH/NIAID R21AI046255Sep 30, 1999 - Sep 29, 2002
    Role: Principal Investigator
    NIH/NINDS R01NS036859Apr 1, 1998 - Mar 31, 2003
    Role: Principal Investigator
    NIH/NHLBI R01HL057883Sep 29, 1996 - Jul 31, 2002
    Role: Principal Investigator
    NIH/NIAID F32AI007893Sep 30, 1988
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wussow F, Chiuppesi F, Meng Z, Martinez J, Nguyen J, Barry PA, Diamond DJ. Exploiting 2A peptides to elicit potent neutralizing antibodies by a multi-subunit herpesvirus glycoprotein complex. J Virol Methods. 2018 01; 251:30-37. PMID: 28989096.
      View in: PubMed
    2. Itell HL, Kaur A, Deere JD, Barry PA, Permar SR. Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections. Curr Opin Virol. 2017 08; 25:126-133. PMID: 28888133.
      View in: PubMed
    3. Smiley Evans T, Lowenstine LJ, Gilardi KV, Barry PA, Ssebide BJ, Kinani JF, Nizeyimana F, Noheri JB, Cranfield MR, Mudakikwa A, Goldstein T, Mazet JAK, Johnson CK. Mountain gorilla lymphocryptovirus has Epstein-Barr virus-like epidemiology and pathology in infants. Sci Rep. 2017 Jul 13; 7(1):5352. PMID: 28706209.
      View in: PubMed
    4. Fan Q, Nelson CS, Bialas KM, Chiuppesi F, Amos J, Gurley TC, Marshall DJ, Eudailey J, Heimsath H, Himes J, Deshpande A, Walter MR, Wussow F, Diamond DJ, Barry PA, Moody MA, Kaur A, Permar SR. Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission. Clin Vaccine Immunol. 2017 May; 24(5). PMID: 28298291.
      View in: PubMed
    5. Chang WL, Gonzalez DF, Kieu HT, Castillo LD, Messaoudi I, Shen X, Tomaras GD, Shacklett BL, Barry PA, Sparger EE. Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques. PLoS One. 2017; 12(1):e0170154. PMID: 28095513.
      View in: PubMed
    6. Eberhardt MK, Deshpande A, Fike J, Short R, Schmidt KA, Blozis SA, Walter MR, Barry PA. Exploitation of Interleukin-10 (IL-10) Signaling Pathways: Alternate Roles of Viral and Cellular IL-10 in Rhesus Cytomegalovirus Infection. J Virol. 2016 Nov 01; 90(21):9920-9930. PMID: 27558431.
      View in: PubMed
    7. Deere JD, Chang WL, Castillo LD, Schmidt KA, Kieu HT, Renzette N, Kowalik T, Barthold SW, Shacklett BL, Barry PA, Sparger EE. Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS. PLoS One. 2016; 11(5):e0155629. PMID: 27182601.
      View in: PubMed
    8. Yue Y, Kaur A, Lilja A, Diamond DJ, Walter MR, Barry PA. The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains. J Gen Virol. 2016 Jun; 97(6):1426-38. PMID: 26974598.
      View in: PubMed
    9. Bialas KM, Tanaka T, Tran D, Varner V, Cisneros De La Rosa E, Chiuppesi F, Wussow F, Kattenhorn L, Macri S, Kunz EL, Estroff JA, Kirchherr J, Yue Y, Fan Q, Lauck M, O'Connor DH, Hall AH, Xavier A, Diamond DJ, Barry PA, Kaur A, Permar SR. Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13645-50. PMID: 26483473.
      View in: PubMed
    10. Chiuppesi F, Wussow F, Johnson E, Bian C, Zhuo M, Rajakumar A, Barry PA, Britt WJ, Chakraborty R, Diamond DJ. Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection. J Virol. 2015 Dec; 89(23):11884-98. PMID: 26378171.
      View in: PubMed
    11. Oxford KL, Dela Pena-Ponce MGA, Jensen K, Eberhardt MK, Spinner A, Van Rompay KK, Rigdon J, Mollan KR, Krishnan VV, Hudgens MG, Barry PA, De Paris K. The interplay between immune maturation, age, chronic viral infection and environment. Immun Ageing. 2015; 12:3. PMID: 25991918.
      View in: PubMed
    12. Barry PA. Exploiting viral natural history for vaccine development. Med Microbiol Immunol. 2015 Jun; 204(3):255-62. PMID: 25794555.
      View in: PubMed
    13. Wussow F, Chiuppesi F, Martinez J, Campo J, Johnson E, Flechsig C, Newell M, Tran E, Ortiz J, La Rosa C, Herrmann A, Longmate J, Chakraborty R, Barry PA, Diamond DJ. Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex. PLoS Pathog. 2014 Nov; 10(11):e1004524. PMID: 25412505; PMCID: PMC4239111.
    14. Assaf BT, Mansfield KG, Strelow L, Westmoreland SV, Barry PA, Kaur A. Limited dissemination and shedding of the UL128 complex-intact, UL/b'-defective rhesus cytomegalovirus strain 180.92. J Virol. 2014 Aug; 88(16):9310-20. PMID: 24899204; PMCID: PMC4136270.
    15. Deere JD, Barry PA. Using the nonhuman primate model of HCMV to guide vaccine development. Viruses. 2014 Mar 27; 6(4):1483-501. PMID: 24681748; PMCID: PMC4014706.
    16. Eberhardt MK, Barry PA. Pathogen manipulation of cIL-10 signaling pathways: opportunities for vaccine development? Curr Top Microbiol Immunol. 2014; 380:93-128. PMID: 25004815.
      View in: PubMed
    17. Lemay DG, Hovey RC, Hartono SR, Hinde K, Smilowitz JT, Ventimiglia F, Schmidt KA, Lee JW, Islas-Trejo A, Silva PI, Korf I, Medrano JF, Barry PA, German JB. Sequencing the transcriptome of milk production: milk trumps mammary tissue. BMC Genomics. 2013 Dec 12; 14:872. PMID: 24330573; PMCID: PMC3871720.
    18. Eberhardt MK, Deshpande A, Chang WL, Barthold SW, Walter MR, Barry PA. Vaccination against a virus-encoded cytokine significantly restricts viral challenge. J Virol. 2013 Nov; 87(21):11323-31. PMID: 23946461; PMCID: PMC3807330.
    19. Wussow F, Yue Y, Martinez J, Deere JD, Longmate J, Herrmann A, Barry PA, Diamond DJ. A vaccine based on the rhesus cytomegalovirus UL128 complex induces broadly neutralizing antibodies in rhesus macaques. J Virol. 2013 Feb; 87(3):1322-32. PMID: 23152525; PMCID: PMC3554163.
    20. Malouli D, Nakayasu ES, Viswanathan K, Camp DG, Chang WL, Barry PA, Smith RD, Früh K. Reevaluation of the coding potential and proteomic analysis of the BAC-derived rhesus cytomegalovirus strain 68-1. J Virol. 2012 Sep; 86(17):8959-73. PMID: 22718821; PMCID: PMC3416160.
    21. dela Pena MG, Strelow L, Barry PA, Abel K. Use of specific-pathogen-free (SPF) rhesus macaques to better model oral pediatric cytomegalovirus infection. J Med Primatol. 2012 Jun; 41(3):225-9. PMID: 22620273; PMCID: PMC3367395.
    22. Eberhardt MK, Chang WL, Logsdon NJ, Yue Y, Walter MR, Barry PA. Host immune responses to a viral immune modulating protein: immunogenicity of viral interleukin-10 in rhesus cytomegalovirus-infected rhesus macaques. PLoS One. 2012; 7(5):e37931. PMID: 22655082.
      View in: PubMed
    23. Assaf BT, Mansfield KG, Westmoreland SV, Kaur A, Oxford KL, Diamond DJ, Barry PA. Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection. J Virol. 2012 Jun; 86(11):6354-7. PMID: 22491451.
      View in: PubMed
    24. Logsdon NJ, Eberhardt MK, Allen CE, Barry PA, Walter MR. Design and analysis of rhesus cytomegalovirus IL-10 mutants as a model for novel vaccines against human cytomegalovirus. PLoS One. 2011; 6(11):e28127. PMID: 22132227; PMCID: PMC3221699.
    25. Hu H, Gama L, Aye PP, Clements JE, Barry PA, Lackner AA, Weissman D. SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques. Retrovirology. 2011 Jul 13; 8:57. PMID: 21752277.
      View in: PubMed
    26. Oxford KL, Strelow L, Yue Y, Chang WL, Schmidt KA, Diamond DJ, Barry PA. Open reading frames carried on UL/b' are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys. J Virol. 2011 May; 85(10):5105-14. PMID: 21389128; PMCID: PMC3126184.
    27. Abel K, Martinez J, Yue Y, Lacey SF, Wang Z, Strelow L, Dasgupta A, Li Z, Schmidt KA, Oxford KL, Assaf B, Longmate JA, Diamond DJ, Barry PA. Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques. J Virol. 2011 Mar; 85(6):2878-90. PMID: 21191005; PMCID: PMC3067943.
    28. Chang WL, Barry PA. Attenuation of innate immunity by cytomegalovirus IL-10 establishes a long-term deficit of adaptive antiviral immunity. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22647-52. PMID: 21149711; PMCID: PMC3012498.
    29. White JA, Todd PA, Yee JL, Kalman-Bowlus A, Rodgers KS, Yang X, Wong SW, Barry P, Lerche NW. Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta). Comp Med. 2009 Aug; 59(4):383-90. PMID: 19712580; PMCID: PMC2779215.
    30. Sparger EE, Gardner MB, Barry PA. Exploiting the natural history of cytomegalovirus to vaccinate against HIV. Expert Rev Vaccines. 2009 Aug; 8(8):993-7. PMID: 19627183.
      View in: PubMed
    31. Slobedman B, Barry PA, Spencer JV, Avdic S, Abendroth A. Virus-encoded homologs of cellular interleukin-10 and their control of host immune function. J Virol. 2009 Oct; 83(19):9618-29. PMID: 19640997; PMCID: PMC2747999.
    32. Chang WL, Barry PA, Szubin R, Wang D, Baumgarth N. Human cytomegalovirus suppresses type I interferon secretion by plasmacytoid dendritic cells through its interleukin 10 homolog. Virology. 2009 Aug 01; 390(2):330-7. PMID: 19524994; PMCID: PMC2747589.
    33. Nicholson IP, Sutherland JS, Chaudry TN, Blewett EL, Barry PA, Nicholl MJ, Preston CM. Properties of virion transactivator proteins encoded by primate cytomegaloviruses. Virol J. 2009 May 27; 6:65. PMID: 19473490; PMCID: PMC2693105.
    34. Abel K, Strelow L, Yue Y, Eberhardt MK, Schmidt KA, Barry PA. A heterologous DNA prime/protein boost immunization strategy for rhesus cytomegalovirus. Vaccine. 2008 Nov 05; 26(47):6013-25. PMID: 18760319; PMCID: PMC2747630.
    35. Oxford KL, Eberhardt MK, Yang KW, Strelow L, Kelly S, Zhou SS, Barry PA. Protein coding content of the UL)b' region of wild-type rhesus cytomegalovirus. Virology. 2008 Mar 30; 373(1):181-8. PMID: 18068749; PMCID: PMC2766279.
    36. Barry PA, Strelow L. Development of breeding populations of rhesus macaques (Macaca mulatta) that are specific pathogen-free for rhesus cytomegalovirus. Comp Med. 2008 Feb; 58(1):43-6. PMID: 19793455; PMCID: PMC2703159.
    37. Yue Y, Wang Z, Abel K, Li J, Strelow L, Mandarino A, Eberhardt MK, Schmidt KA, Diamond DJ, Barry PA. Evaluation of recombinant modified vaccinia Ankara virus-based rhesus cytomegalovirus vaccines in rhesus macaques. Med Microbiol Immunol. 2008 Jun; 197(2):117-23. PMID: 18196272.
      View in: PubMed
    38. Yue Y, Barry PA. Rhesus cytomegalovirus a nonhuman primate model for the study of human cytomegalovirus. Adv Virus Res. 2008; 72:207-26. PMID: 19081492.
      View in: PubMed
    39. Lilja AE, Chang WL, Barry PA, Becerra SP, Shenk TE. Functional genetic analysis of rhesus cytomegalovirus: Rh01 is an epithelial cell tropism factor. J Virol. 2008 Mar; 82(5):2170-81. PMID: 18094178; PMCID: PMC2258942.
    40. Chang WL, Baumgarth N, Eberhardt MK, Lee CY, Baron CA, Gregg JP, Barry PA. Exposure of myeloid dendritic cells to exogenous or endogenous IL-10 during maturation determines their longevity. J Immunol. 2007 Jun 15; 178(12):7794-804. PMID: 17548617.
      View in: PubMed
    41. Yue Y, Kaur A, Eberhardt MK, Kassis N, Zhou SS, Tarantal AF, Barry PA. Immunogenicity and protective efficacy of DNA vaccines expressing rhesus cytomegalovirus glycoprotein B, phosphoprotein 65-2, and viral interleukin-10 in rhesus macaques. J Virol. 2007 Feb; 81(3):1095-109. PMID: 17108040; PMCID: PMC1797524.
    42. Bell SA, Balasuriya UB, Gardner IA, Barry PA, Wilson WD, Ferraro GL, MacLachlan NJ. Temporal detection of equine herpesvirus infections of a cohort of mares and their foals. Vet Microbiol. 2006 Sep 10; 116(4):249-57. PMID: 16774810.
      View in: PubMed
    43. Jones-Engel L, Engel GA, Heidrich J, Chalise M, Poudel N, Viscidi R, Barry PA, Allan JS, Grant R, Kyes R. Temple monkeys and health implications of commensalism, Kathmandu, Nepal. Emerg Infect Dis. 2006 Jun; 12(6):900-6. PMID: 16707044; PMCID: PMC3373059.
    44. Yue Y, Kaur A, Zhou SS, Barry PA. Characterization and immunological analysis of the rhesus cytomegalovirus homologue (Rh112) of the human cytomegalovirus UL83 lower matrix phosphoprotein (pp65). J Gen Virol. 2006 Apr; 87(Pt 4):777-87. PMID: 16528025.
      View in: PubMed
    45. Barry PA, Lockridge KM, Salamat S, Tinling SP, Yue Y, Zhou SS, Gospe SM, Britt WJ, Tarantal AF. Nonhuman primate models of intrauterine cytomegalovirus infection. ILAR J. 2006; 47(1):49-64. PMID: 16391431.
      View in: PubMed
    46. Khan IH, Mendoza S, Yee J, Deane M, Venkateswaran K, Zhou SS, Barry PA, Lerche NW, Luciw PA. Simultaneous detection of antibodies to six nonhuman-primate viruses by multiplex microbead immunoassay. Clin Vaccine Immunol. 2006 Jan; 13(1):45-52. PMID: 16425999; PMCID: PMC1356626.
    47. Carlson JR, Chang WL, Zhou SS, Tarantal AF, Barry PA. Rhesus brain microvascular endothelial cells are permissive for rhesus cytomegalovirus infection. J Gen Virol. 2005 Mar; 86(Pt 3):545-9. PMID: 15722513.
      View in: PubMed
    48. Chang WL, Baumgarth N, Yu D, Barry PA. Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality. J Virol. 2004 Aug; 78(16):8720-31. PMID: 15280480; PMCID: PMC479089.
    49. North TW, Sequar G, Townsend LB, Drach JC, Barry PA. Rhesus cytomegalovirus is similar to human cytomegalovirus in susceptibility to benzimidazole nucleosides. Antimicrob Agents Chemother. 2004 Jul; 48(7):2760-5. PMID: 15215146; PMCID: PMC434194.
    50. Barry PA. Efficient electroporation of mammalian cells in culture. Methods Mol Biol. 2004; 245:207-14. PMID: 14707381.
      View in: PubMed
    51. Yue Y, Zhou SS, Barry PA. Antibody responses to rhesus cytomegalovirus glycoprotein B in naturally infected rhesus macaques. J Gen Virol. 2003 Dec; 84(Pt 12):3371-9. PMID: 14645918.
      View in: PubMed
    52. Wasson K, Barry PA. Molecular characterization of Encephalitozoon intestinalis (Microspora) replication kinetics in a murine intestinal cell line. J Eukaryot Microbiol. 2003 May-Jun; 50(3):169-74. PMID: 12836873.
      View in: PubMed
    53. Kaur A, Kassis N, Hale CL, Simon M, Elliott M, Gomez-Yafal A, Lifson JD, Desrosiers RC, Wang F, Barry P, Mach M, Johnson RP. Direct relationship between suppression of virus-specific immunity and emergence of cytomegalovirus disease in simian AIDS. J Virol. 2003 May; 77(10):5749-58. PMID: 12719568; PMCID: PMC154043.
    54. Chang WL, Barry PA. Cloning of the full-length rhesus cytomegalovirus genome as an infectious and self-excisable bacterial artificial chromosome for analysis of viral pathogenesis. J Virol. 2003 May; 77(9):5073-83. PMID: 12692210; PMCID: PMC153942.
    55. Andrade MR, Yee J, Barry P, Spinner A, Roberts JA, Cabello PH, Leite JP, Lerche NW. Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil. Am J Primatol. 2003 Mar; 59(3):123-8. PMID: 12619046.
      View in: PubMed
    56. Chang WL, Tarantal AF, Zhou SS, Borowsky AD, Barry PA. A recombinant rhesus cytomegalovirus expressing enhanced green fluorescent protein retains the wild-type phenotype and pathogenicity in fetal macaques. J Virol. 2002 Sep; 76(18):9493-504. PMID: 12186931; PMCID: PMC136446.
    57. Sequar G, Britt WJ, Lakeman FD, Lockridge KM, Tarara RP, Canfield DR, Zhou SS, Gardner MB, Barry PA. Experimental coinfection of rhesus macaques with rhesus cytomegalovirus and simian immunodeficiency virus: pathogenesis. J Virol. 2002 Aug; 76(15):7661-71. PMID: 12097580; PMCID: PMC136401.
    58. Jones BC, Logsdon NJ, Josephson K, Cook J, Barry PA, Walter MR. Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9404-9. PMID: 12093920; PMCID: PMC123153.
    59. Chang WL, Kirchoff V, Pari GS, Barry PA. Replication of rhesus cytomegalovirus in life-expanded rhesus fibroblasts expressing human telomerase. J Virol Methods. 2002 Jul; 104(2):135-46. PMID: 12088823.
      View in: PubMed
    60. Spencer JV, Lockridge KM, Barry PA, Lin G, Tsang M, Penfold ME, Schall TJ. Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10. J Virol. 2002 Feb; 76(3):1285-92. PMID: 11773404; PMCID: PMC135865.