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Luke Anthony Wittenburg

Title(s)Assistant Professor, SCHOOL OF VETERINARY MEDICINE
SchoolUniversity of California, Davis
Phone530-754-5711
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Alegre F, Ormonde AR, Godinez DR, Illendula A, Bushweller JH, Wittenburg LA. The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma. Vet Comp Oncol. 2019 Aug 05. PMID: 31381810.
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    2. Kirsch M, Weisse C, Berent A, Clifford C, Leibman N, Wittenburg L, Solomon SB, Lamb K. Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors. Can J Vet Res. 2019 Jul; 83(3):187-196. PMID: 31308591.
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    3. Wittenburg LA, Weishaar K, Ramirez D, Gustafson DL. Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers. Vet Comp Oncol. 2019 Jun; 17(2):147-154. PMID: 30638304.
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    4. Alegre F, Ormonde AR, Snider KM, Woolard K, Yu AM, Wittenburg LA. A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma. PLoS One. 2018; 13(12):e0209941. PMID: 30596759.
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    5. Wittenburg LA, Ramirez D, Conger H, Gustafson DL. Simultaneous absolute quantitation of ATP-binding cassette transporters in normal dog tissues by signature peptide analysis using a LC/MS/MS method. Res Vet Sci. 2019 Feb; 122:93-101. PMID: 30500618.
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    6. Fitzpatrick RL, Quimby JM, Benson KK, Ramirez D, Sieberg LG, Wittenburg LA, Gustafson DL. In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease. J Vet Intern Med. 2018 Nov; 32(6):1951-1957. PMID: 30307637.
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    7. Withers SS, York D, Johnson E, Al-Nadaf S, Skorupski KA, Rodriguez CO, Burton JH, Guerrero T, Sein K, Wittenburg L, Rebhun RB. In vitro and in vivo activity of liposome-encapsulated curcumin for naturally occurring canine cancers. Vet Comp Oncol. 2018 Dec; 16(4):571-579. PMID: 30088848.
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    8. Bartner LR, McGrath S, Rao S, Hyatt LK, Wittenburg LA. Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs. Can J Vet Res. 2018 Jul; 82(3):178-183. PMID: 30026641.
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    9. Herndon AK, Quimby JM, Sieberg LG, Davis L, Caress AL, Ligas S, Hansen RJ, Wittenburg LA, Gustafson DL. Preliminary pharmacokinetics of intravenous and subcutaneous dolasetron and pharmacodynamics of subcutaneous dolasetron in healthy cats. J Feline Med Surg. 2018 08; 20(8):721-727. PMID: 28905667.
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    10. Zajic LB, Herndon AK, Sieberg LG, Caress AL, Morgan PK, Hansen RJ, Wittenburg LA, Gustafson DL, Quimby JM. Assessment of absorption of transdermal ondansetron in normal research cats. J Feline Med Surg. 2017 Dec; 19(12):1245-1248. PMID: 28112563.
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    11. Goehring LS, Brandes K, Ashton LV, Wittenburg LA, Olea-Popelka FJ, Lunn DP, Soboll Hussey G. Anti-inflammatory drugs decrease infection of brain endothelial cells with EHV-1 in vitro. Equine Vet J. 2017 Sep; 49(5):629-636. PMID: 27864898.
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    12. Worley DR, Hansen RJ, Wittenburg LA, Chubb LS, Gustafson DL. Docetaxel Accumulates in Lymphatic Circulation Following Subcutaneous Delivery Compared to Intravenous Delivery in Rats. Anticancer Res. 2016 10; 36(10):5071-5078. PMID: 27798866.
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    13. Benson KK, Zajic LB, Morgan PK, Brown SR, Hansen RJ, Lunghofer PJ, Wittenburg LA, Gustafson DL, Quimby JM. Drug exposure and clinical effect of transdermal mirtazapine in healthy young cats: a pilot study. J Feline Med Surg. 2017 Oct; 19(10):998-1006. PMID: 27613493.
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    14. Cox KS, Nelson BB, Wittenburg L, Gold JR. Plasma, subcutaneous tissue and bone concentrations of ceftiofur sodium after regional limb perfusion in horses. Equine Vet J. 2017 May; 49(3):341-344. PMID: 27458113.
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    15. Colbath AC, Wittenburg LA, Gold JR, McIlwraith CW, Moorman VJ. The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse. Vet Surg. 2016 Aug; 45(6):798-803. PMID: 27416788.
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    16. Fitzpatrick RL, Wittenburg LA, Hansen RJ, Gustafson DL, Quimby JM. Limited sampling pharmacokinetics of subcutaneous ondansetron in healthy geriatric cats, cats with chronic kidney disease, and cats with liver disease. J Vet Pharmacol Ther. 2016 Aug; 39(4):350-5. PMID: 26667224.
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    17. Watson MK, Wittenburg LA, Bui CT, Jarosz KA, Gustafson DL, Johnston MS. Pharmacokinetics and bioavailability of orbifloxacin oral suspension in New Zealand White rabbits (Oryctolagus cuniculus). Am J Vet Res. 2015 Nov; 76(11):946-51. PMID: 26512539.
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    18. Myers JA, Wittenburg LA, Olver CS, Martinez CM, Bright JM. Pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban after oral and intravenous administration to cats. Am J Vet Res. 2015 Aug; 76(8):732-8. PMID: 26207972.
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    19. Barnard RA, Wittenburg LA, Amaravadi RK, Gustafson DL, Thorburn A, Thamm DH. Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma. Autophagy. 2014 Aug; 10(8):1415-25. PMID: 24991836.
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    20. Scofield D, Black J, Wittenburg L, Gustafson D, Ferris R, Hatzel J, Traub-Dargatz J, McCue P. Endometrial tissue and blood plasma concentration of ceftiofur and metabolites following intramuscular administration of ceftiofur crystalline free acid to mares. Equine Vet J. 2014 Sep; 46(5):606-10. PMID: 24111546.
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    21. Théon AP, Pusterla N, Magdesian KG, Wittenburg L, Marmulak T, Wilson WD. A pilot phase II study of the efficacy and biosafety of doxorubicin chemotherapy in tumor-bearing equidae. J Vet Intern Med. 2013 Nov-Dec; 27(6):1581-8. PMID: 24107145.
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    22. Arnold TS, Wittenburg LA, Powell CC. Effect of topical naltrexone 0.3% on corneal sensitivity and tear parameters in normal brachycephalic dogs. Vet Ophthalmol. 2014 Sep; 17(5):328-33. PMID: 23802568.
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    23. Wittenburg LA, Thamm DH, Gustafson DL. Development of a limited-sampling model for prediction of doxorubicin exposure in dogs. Vet Comp Oncol. 2014 Jun; 12(2):114-9. PMID: 22747489.
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    24. Wittenburg LA, Ptitsyn AA, Thamm DH. A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcoma. J Cell Biochem. 2012 Mar; 113(3):773-83. PMID: 21976144.
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    25. Wittenburg LA, Gustafson DL. Optimizing preclinical study design in oncology research. Chem Biol Interact. 2011 Apr 25; 190(2-3):73-8. PMID: 21296059.
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    26. Wittenburg LA, Gustafson DL, Thamm DH. Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer. Clin Cancer Res. 2010 Oct 01; 16(19):4832-42. PMID: 20705615.
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    27. Wittenburg LA, Bisson L, Rose BJ, Korch C, Thamm DH. The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin. Cancer Chemother Pharmacol. 2011 Jan; 67(1):83-92. PMID: 20306194.
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