Luke Anthony Wittenburg

Title(s)Associate Professor, School of Veterinary Medicine
SchoolSchool of Veterinary Medicine
Address218 CCAH
CA 95616
Phone530-754-5711
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response. J Immunother Cancer. 2022 06; 10(6). Rebhun RB, York D, Cruz SM, Judge SJ, Razmara AM, Farley LE, Brady RV, Johnson EG, Burton JH, Willcox J, Wittenburg LA, Woolard K, Dunai C, Stewart SL, Sparger EE, Withers SS, Gingrich AA, Skorupski KA, Al-Nadaf S, LeJeune AT, Culp WT, Murphy WJ, Kent MS, Canter RJ. PMID: 35680383; PMCID: PMC9174838.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    2. Prevalence and Clinicopathologic Features of Canine Metastatic Melanoma Involving the Central Nervous System: A Retrospective Analysis and Comparative Review. Front Oncol. 2022; 12:868004. Razmara AM, Wittenburg LA, Al-Nadaf S, Toedebusch RG, Meyers FJ, Toedebusch CM. PMID: 35692802; PMCID: PMC9186031.
      View in: PubMed   Mentions:
    3. Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration. J Vet Intern Med. 2022 Jul; 36(4):1422-1429. Woerde DJ, Wittenburg LA, Dear JD. PMID: 35616184; PMCID: PMC9308414.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Serum concentrations of gabapentin in cats with chronic kidney disease. J Feline Med Surg. 2022 Feb 23; 1098612X221077017. Quimby JM, Lorbach SK, Saffire A, Kennedy A, Wittenburg LA, Aarnes TK, Creighton KJ, Jones SE, Paschall RE, King EM, Bruner CE, Wallinger JN, van Haaften KA. PMID: 35195476; PMCID: PMC9395545.
      View in: PubMed   Mentions:    Fields:    
    5. Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells. Int J Mol Sci. 2021 Dec 02; 22(23). Toedebusch RG, Lucchesi CA, Debebe ET, Wittenburg LA, Chen X, Toedebusch CM. PMID: 34884869; PMCID: PMC8657851.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma. Vet Comp Oncol. 2020 Mar; 18(1):52-63. Alegre F, Ormonde AR, Godinez DR, Illendula A, Bushweller JH, Wittenburg LA. PMID: 31381810; PMCID: PMC7233265.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors. Can J Vet Res. 2019 Jul; 83(3):187-196. Kirsch M, Weisse C, Berent A, Clifford C, Leibman N, Wittenburg L, Solomon SB, Lamb K. PMID: 31308591; PMCID: PMC6587882.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers. Vet Comp Oncol. 2019 Jun; 17(2):147-154. Wittenburg LA, Weishaar K, Ramirez D, Gustafson DL. PMID: 30638304; PMCID: PMC6478528.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    9. A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma. PLoS One. 2018; 13(12):e0209941. Alegre F, Ormonde AR, Snider KM, Woolard K, Yu AM, Wittenburg LA. PMID: 30596759; PMCID: PMC6312226.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    10. Simultaneous absolute quantitation of ATP-binding cassette transporters in normal dog tissues by signature peptide analysis using a LC/MS/MS method. Res Vet Sci. 2019 Feb; 122:93-101. Wittenburg LA, Ramirez D, Conger H, Gustafson DL. PMID: 30500618; PMCID: PMC6522139.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease. J Vet Intern Med. 2018 Nov; 32(6):1951-1957. Fitzpatrick RL, Quimby JM, Benson KK, Ramirez D, Sieberg LG, Wittenburg LA, Gustafson DL. PMID: 30307637; PMCID: PMC6272035.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. In vitro and in vivo activity of liposome-encapsulated curcumin for naturally occurring canine cancers. Vet Comp Oncol. 2018 Dec; 16(4):571-579. Withers SS, York D, Johnson E, Al-Nadaf S, Skorupski KA, Rodriguez CO, Burton JH, Guerrero T, Sein K, Wittenburg L, Rebhun RB. PMID: 30088848; PMCID: PMC6234083.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    13. Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs. Can J Vet Res. 2018 Jul; 82(3):178-183. Bartner LR, McGrath S, Rao S, Hyatt LK, Wittenburg LA. PMID: 30026641; PMCID: PMC6038832.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    14. Preliminary pharmacokinetics of intravenous and subcutaneous dolasetron and pharmacodynamics of subcutaneous dolasetron in healthy cats. J Feline Med Surg. 2018 08; 20(8):721-727. Herndon AK, Quimby JM, Sieberg LG, Davis L, Caress AL, Ligas S, Hansen RJ, Wittenburg LA, Gustafson DL. PMID: 28905667.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Assessment of absorption of transdermal ondansetron in normal research cats. J Feline Med Surg. 2017 Dec; 19(12):1245-1248. Zajic LB, Herndon AK, Sieberg LG, Caress AL, Morgan PK, Hansen RJ, Wittenburg LA, Gustafson DL, Quimby JM. PMID: 28112563.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    16. Anti-inflammatory drugs decrease infection of brain endothelial cells with EHV-1 in vitro. Equine Vet J. 2017 Sep; 49(5):629-636. Goehring LS, Brandes K, Ashton LV, Wittenburg LA, Olea-Popelka FJ, Lunn DP, Soboll Hussey G. PMID: 27864898.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    17. Docetaxel Accumulates in Lymphatic Circulation Following Subcutaneous Delivery Compared to Intravenous Delivery in Rats. Anticancer Res. 2016 10; 36(10):5071-5078. Worley DR, Hansen RJ, Wittenburg LA, Chubb LS, Gustafson DL. PMID: 27798866; PMCID: PMC5501171.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    18. Drug exposure and clinical effect of transdermal mirtazapine in healthy young cats: a pilot study. J Feline Med Surg. 2017 Oct; 19(10):998-1006. Benson KK, Zajic LB, Morgan PK, Brown SR, Hansen RJ, Lunghofer PJ, Wittenburg LA, Gustafson DL, Quimby JM. PMID: 27613493; PMCID: PMC5647142.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCTClinical Trials
    19. Plasma, subcutaneous tissue and bone concentrations of ceftiofur sodium after regional limb perfusion in horses. Equine Vet J. 2017 May; 49(3):341-344. Cox KS, Nelson BB, Wittenburg L, Gold JR. PMID: 27458113.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCTClinical Trials
    20. The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse. Vet Surg. 2016 Aug; 45(6):798-803. Colbath AC, Wittenburg LA, Gold JR, McIlwraith CW, Moorman VJ. PMID: 27416788.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCTClinical Trials
    21. Limited sampling pharmacokinetics of subcutaneous ondansetron in healthy geriatric cats, cats with chronic kidney disease, and cats with liver disease. J Vet Pharmacol Ther. 2016 Aug; 39(4):350-5. Fitzpatrick RL, Wittenburg LA, Hansen RJ, Gustafson DL, Quimby JM. PMID: 26667224; PMCID: PMC6994184.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    22. Pharmacokinetics and bioavailability of orbifloxacin oral suspension in New Zealand White rabbits (Oryctolagus cuniculus). Am J Vet Res. 2015 Nov; 76(11):946-51. Watson MK, Wittenburg LA, Bui CT, Jarosz KA, Gustafson DL, Johnston MS. PMID: 26512539.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    23. Pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban after oral and intravenous administration to cats. Am J Vet Res. 2015 Aug; 76(8):732-8. Myers JA, Wittenburg LA, Olver CS, Martinez CM, Bright JM. PMID: 26207972.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    24. Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma. Autophagy. 2014 Aug; 10(8):1415-25. Barnard RA, Wittenburg LA, Amaravadi RK, Gustafson DL, Thorburn A, Thamm DH. PMID: 24991836; PMCID: PMC4203518.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCTClinical Trials
    25. Endometrial tissue and blood plasma concentration of ceftiofur and metabolites following intramuscular administration of ceftiofur crystalline free acid to mares. Equine Vet J. 2014 Sep; 46(5):606-10. Scofield D, Black J, Wittenburg L, Gustafson D, Ferris R, Hatzel J, Traub-Dargatz J, McCue P. PMID: 24111546.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    26. A pilot phase II study of the efficacy and biosafety of doxorubicin chemotherapy in tumor-bearing equidae. J Vet Intern Med. 2013 Nov-Dec; 27(6):1581-8. Théon AP, Pusterla N, Magdesian KG, Wittenburg L, Marmulak T, Wilson WD. PMID: 24107145.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic HealthCTClinical Trials
    27. Effect of topical naltrexone 0.3% on corneal sensitivity and tear parameters in normal brachycephalic dogs. Vet Ophthalmol. 2014 Sep; 17(5):328-33. Arnold TS, Wittenburg LA, Powell CC. PMID: 23802568.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    28. Development of a limited-sampling model for prediction of doxorubicin exposure in dogs. Vet Comp Oncol. 2014 Jun; 12(2):114-9. Wittenburg LA, Thamm DH, Gustafson DL. PMID: 22747489; PMCID: PMC3897556.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    29. A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcoma. J Cell Biochem. 2012 Mar; 113(3):773-83. Wittenburg LA, Ptitsyn AA, Thamm DH. PMID: 21976144; PMCID: PMC4667946.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    30. Optimizing preclinical study design in oncology research. Chem Biol Interact. 2011 Apr 25; 190(2-3):73-8. Wittenburg LA, Gustafson DL. PMID: 21296059.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer. Clin Cancer Res. 2010 Oct 01; 16(19):4832-42. Wittenburg LA, Gustafson DL, Thamm DH. PMID: 20705615; PMCID: PMC2948605.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCTClinical Trials
    32. The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin. Cancer Chemother Pharmacol. 2011 Jan; 67(1):83-92. Wittenburg LA, Bisson L, Rose BJ, Korch C, Thamm DH. PMID: 20306194; PMCID: PMC2916050.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
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