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Laura Marcu

Title(s)Professor, Biomedical Engineering
SchoolUniversity of California, Davis
Phone530-752-0288
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shklover J, McMasters J, Alfonso-Garcia A, Higuita ML, Panitch A, Marcu L, Griffiths L. Bovine pericardial extracellular matrix niche modulates human aortic endothelial cell phenotype and function. Sci Rep. 2019 Nov 13; 9(1):16688. PMID: 31723198.
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    2. Bec J, Li C, Marcu L. Broadband, freeform focusing micro-optics for a side-viewing imaging catheter. Opt Lett. 2019 Oct 15; 44(20):4961-4964. PMID: 31613239.
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    3. Li C, Alfonso-Garcia A, McMasters J, Bec J, Weyers B, Uyesaka L, Griffiths L, Panitch A, Marcu L. Simultaneous intraluminal imaging of tissue autofluorescence and eGFP-labeled cells in engineered vascular grafts inside a bioreactor. Methods Appl Fluoresc. 2019 Sep 20; 7(4):044003. PMID: 31505471.
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    4. Alfonso-Garcia A, Bec J, Sridharan Weaver S, Hartl B, Unger J, Bobinski M, Lechpammer M, Girgis F, Boggan J, Marcu L. Real-time augmented reality for delineation of surgical margins during neurosurgery using autofluorescence lifetime contrast. J Biophotonics. 2019 Jul 15; e201900108. PMID: 31304655.
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    5. Alfonso-Garcia A, Li C, Bec J, Yankelevich D, Marcu L, Sherlock B. Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. Opt Lett. 2019 Jul 01; 44(13):3350-3353. PMID: 31259958.
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    6. Sherlock BE, Li C, Zhou X, Alfonso-Garcia A, Bec J, Yankelevich D, Marcu L. Multiscale, multispectral fluorescence lifetime imaging using a double-clad fiber. Opt Lett. 2019 May 01; 44(9):2302-2305. PMID: 31042209.
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    7. Yang W, Mondol AS, Stiebing C, Marcu L, Popp J, Schie IW. Raman ChemLighter: Fiber optic Raman probe imaging in combination with augmented chemical reality. J Biophotonics. 2019 Jul; 12(7):e201800447. PMID: 30848073.
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    8. Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA. Non-destructive detection of matrix stabilization correlates with enhanced mechanical properties of self-assembled articular cartilage. J Tissue Eng Regen Med. 2019 04; 13(4):637-648. PMID: 30770656.
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    9. Gorpas D, Phipps J, Bec J, Ma D, Dochow S, Yankelevich D, Sorger J, Popp J, Bewley A, Gandour-Edwards R, Marcu L, Farwell DG. Autofluorescence lifetime augmented reality as a means for real-time robotic surgery guidance in human patients. Sci Rep. 2019 Feb 04; 9(1):1187. PMID: 30718542.
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    10. Zhou X, Haudenschild AK, Sherlock BE, Hu JC, Leach JK, Athanasiou KA, Marcu L. Detection of glycosaminoglycan loss in articular cartilage by fluorescence lifetime imaging. J Biomed Opt. 2018 12; 23(12):1-8. PMID: 30578627.
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    11. Alfonso-Garcia A, Haudenschild AK, Marcu L. Label-free assessment of carotid artery biochemical composition using fiber-based fluorescence lifetime imaging. Biomed Opt Express. 2018 Sep 01; 9(9):4064-4076. PMID: 30615748.
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    12. Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA. Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties. Eur Cell Mater. 2018 07 27; 36:30-43. PMID: 30051455.
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    13. Li C, Shklover J, Parvizi M, Sherlock BE, Alfonso Garcia A, Haudenschild AK, Griffiths LG, Marcu L. Label-Free Assessment of Collagenase Digestion on Bovine Pericardium Properties by Fluorescence Lifetime Imaging. Ann Biomed Eng. 2018 Nov; 46(11):1870-1881. PMID: 30003502.
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    14. Hartl BA, Ma HSW, Sridharan S, Hansen KS, Kent MS, Gorin F, Fragoso RC, Marcu L. Label-free fluorescence lifetime spectroscopy detects radiation-induced necrotic changes in live brain in real-time. Biomed Opt Express. 2018 Aug 01; 9(8):3559-3580. PMID: 30338140.
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    15. Alfonso-Garcia A, Shklover J, Sherlock BE, Panitch A, Griffiths LG, Marcu L. Fiber-based fluorescence lifetime imaging of recellularization processes on vascular tissue constructs. J Biophotonics. 2018 09; 11(9):e201700391. PMID: 29781171.
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    16. Lagarto JL, Phipps JE, Faller L, Ma D, Unger J, Bec J, Griffey S, Sorger J, Farwell DG, Marcu L. Electrocautery effects on fluorescence lifetime measurements: An in vivo study in the oral cavity. J Photochem Photobiol B. 2018 08; 185:90-99. PMID: 29883910.
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    17. Sherlock BE, Harvestine JN, Mitra D, Haudenschild A, Hu J, Athanasiou KA, Leach JK, Marcu L. Nondestructive assessment of collagen hydrogel cross-linking using time-resolved autofluorescence imaging. J Biomed Opt. 2018 03; 23(3):1-9. PMID: 29512359.
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    18. Gorpas D, Davari P, Bec J, Fung MA, Marcu L, Farwell DG, Fazel N. Time-resolved fluorescence spectroscopy for the diagnosis of oral lichen planus. Clin Exp Dermatol. 2018 Jul; 43(5):546-552. PMID: 29436013.
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    19. Unger J, Sun T, Chen YL, Phipps JE, Bold RJ, Darrow MA, Ma KL, Marcu L. Method for accurate registration of tissue autofluorescence imaging data with corresponding histology: a means for enhanced tumor margin assessment. J Biomed Opt. 2018 01; 23(1):1-11. PMID: 29297208.
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    20. Phipps JE, Gorpas D, Unger J, Darrow M, Bold RJ, Marcu L. Automated detection of breast cancer in resected specimens with fluorescence lifetime imaging. Phys Med Biol. 2017 12 14; 63(1):015003. PMID: 29099721.
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    21. Marcu L, Boppart SA, Hutchinson MR, Popp J, Wilson BC. Biophotonics: the big picture. J Biomed Opt. 2017 12; 23(2):1-7. PMID: 29275543.
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    22. Boppart SA, Brown JQ, Farah CS, Kho E, Marcu L, Saunders CM, Sterenborg HJCM. Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment. J Biomed Opt. 2017 12; 23(2):1-10. PMID: 29288572.
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    23. Sherlock BE, Phipps JE, Bec J, Marcu L. Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber. Opt Lett. 2017 Oct 01; 42(19):3753-3756. PMID: 28957119.
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    24. Fereidouni F, Gorpas D, Ma D, Fatakdawala H, Marcu L. Rapid fluorescence lifetime estimation with modified phasor approach and Laguerre deconvolution: a comparative study. Methods Appl Fluoresc. 2017 09 01; 5(3):035003. PMID: 28644150.
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    25. Bec J, Phipps JE, Gorpas D, Ma D, Fatakdawala H, Margulies KB, Southard JA, Marcu L. In vivo label-free structural and biochemical imaging of coronary arteries using an integrated ultrasound and multispectral fluorescence lifetime catheter system. Sci Rep. 2017 08 21; 7(1):8960. PMID: 28827758.
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    26. Marcu L, Hillman EMC. In vivo Optical Imaging / Intravital Microscopy. J Biophotonics. 2017 06; 10(6-7):760-761. PMID: 28661586.
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    27. Hartl BA, Ma HSW, Hansen KS, Perks J, Kent MS, Fragoso RC, Marcu L. The effect of radiation dose on the onset and progression of radiation-induced brain necrosis in the rat model. Int J Radiat Biol. 2017 07; 93(7):676-682. PMID: 28306402.
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    28. Ma D, Liu J, Qi J, Marcu L. Reply to Comment: 'A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-square deconvolution with Laguerre expansion'. Phys Med Biol. 2017 02 21; 62(4):1637-1641. PMID: 28145280.
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    29. Bourantas CV, Jaffer FA, Gijsen FJ, van Soest G, Madden SP, Courtney BK, Fard AM, Tenekecioglu E, Zeng Y, van der Steen AFW, Emelianov S, Muller J, Stone PH, Marcu L, Tearney GJ, Serruys PW. Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology. Eur Heart J. 2017 02 07; 38(6):400-412. PMID: 27118197.
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    30. Mitra D, Fatakdawala H, Nguyen-Truong M, Creecy A, Nyman J, Marcu L, Leach JK. Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy. ACS Biomater Sci Eng. 2017 Sep 11; 3(9):1944-1954. PMID: 28944287.
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    31. Dochow S, Fatakdawala H, Phipps JE, Ma D, Bocklitz T, Schmitt M, Bishop JW, Margulies KB, Marcu L, Popp J. Comparing Raman and fluorescence lifetime spectroscopy from human atherosclerotic lesions using a bimodal probe. J Biophotonics. 2016 09; 9(9):958-66. PMID: 27003796.
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    32. Gorpas D, Ma D, Bec J, Yankelevich DR, Marcu L. Real-Time Visualization of Tissue Surface Biochemical Features Derived From Fluorescence Lifetime Measurements. IEEE Trans Med Imaging. 2016 08; 35(8):1802-11. PMID: 26890641.
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    33. Hartl BA, Hirschberg H, Marcu L, Cherry SR. Activating Photodynamic Therapy in vitro with Cerenkov Radiation Generated from Yttrium-90. J Environ Pathol Toxicol Oncol. 2016; 35(2):185-92. PMID: 27481495.
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    34. Dochow S, Ma D, Latka I, Bocklitz T, Hartl B, Bec J, Fatakdawala H, Marple E, Urmey K, Wachsmann-Hogiu S, Schmitt M, Marcu L, Popp J. Combined fiber probe for fluorescence lifetime and Raman spectroscopy. Anal Bioanal Chem. 2015 Nov; 407(27):8291-301. PMID: 26093843.
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    35. Fatakdawala H, Gorpas D, Bishop JW, Bec J, Ma D, Southard JA, Margulies KB, Marcu L. Fluorescence Lifetime Imaging Combined with Conventional Intravascular Ultrasound for Enhanced Assessment of Atherosclerotic Plaques: an Ex Vivo Study in Human Coronary Arteries. J Cardiovasc Transl Res. 2015 Jun; 8(4):253-63. PMID: 25931307.
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    36. Ma D, Bec J, Gorpas D, Yankelevich D, Marcu L. Technique for real-time tissue characterization based on scanning multispectral fluorescence lifetime spectroscopy (ms-TRFS). Biomed Opt Express. 2015 Mar 01; 6(3):987-1002. PMID: 25798320.
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    37. Hartl BA, Hirschberg H, Marcu L, Cherry SR. Characterizing low fluence thresholds for in vitro photodynamic therapy. Biomed Opt Express. 2015 Mar 01; 6(3):770-9. PMID: 25798302.
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    38. Gorpas D, Fatakdawala H, Bec J, Ma D, Yankelevich DR, Qi J, Marcu L. Fluorescence lifetime imaging and intravascular ultrasound: co-registration study using ex vivo human coronaries. IEEE Trans Med Imaging. 2015 Jan; 34(1):156-66. PMID: 25163056.
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    39. Fatakdawala H, Griffiths LG, Humphrey S, Marcu L. Time-resolved fluorescence spectroscopy and ultrasound backscatter microscopy for nondestructive evaluation of vascular grafts. J Biomed Opt. 2014 Aug; 19(8):080503. PMID: 25147960.
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    40. Ghata N, Aldredge RC, Bec J, Marcu L. Computational analysis of the effectiveness of blood flushing with saline injection from an intravascular diagnostic catheter. Int J Numer Method Biomed Eng. 2014 Nov; 30(11):1278-93. PMID: 24953876.
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    41. Ma D, Bec J, Yankelevich DR, Gorpas D, Fatakdawala H, Marcu L. Rotational multispectral fluorescence lifetime imaging and intravascular ultrasound: bimodal system for intravascular applications. J Biomed Opt. 2014 Jun; 19(6):066004. PMID: 24898604.
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    42. Yankelevich DR, Ma D, Liu J, Sun Y, Sun Y, Bec J, Elson DS, Marcu L. Design and evaluation of a device for fast multispectral time-resolved fluorescence spectroscopy and imaging. Rev Sci Instrum. 2014 Mar; 85(3):034303. PMID: 24689603.
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    43. Yankelevich D, González JE, Cudney RS, Ríos LA, Marcu L. Development of a new pulsed source for photoacoustic imaging based on aperiodically poled lithium niobate. Biomed Opt Express. 2014 Feb 01; 5(2):468-73. PMID: 24575341.
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    44. Lam M, Chaudhari AJ, Sun Y, Zhou F, Dobbie A, Gandour-Edwards RF, Tinling SP, Farwell DG, Monsky WL, Shung KK, Marcu L. Ultrasound backscatter microscopy for imaging of oral carcinoma. J Ultrasound Med. 2013 Oct; 32(10):1789-97. PMID: 24065260.
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    45. Fatakdawala H, Poti S, Zhou F, Sun Y, Bec J, Liu J, Yankelevich DR, Tinling SP, Gandour-Edwards RF, Farwell DG, Marcu L. Multimodal in vivo imaging of oral cancer using fluorescence lifetime, photoacoustic and ultrasound techniques. Biomed Opt Express. 2013; 4(9):1724-41. PMID: 24049693.
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    46. Sun Y, Phipps JE, Meier J, Hatami N, Poirier B, Elson DS, Farwell DG, Marcu L. Endoscopic fluorescence lifetime imaging for in vivo intraoperative diagnosis of oral carcinoma. Microsc Microanal. 2013 Aug; 19(4):791-8. PMID: 23702007.
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    47. Bec J, Ma DM, Yankelevich DR, Liu J, Ferrier WT, Southard J, Marcu L. Multispectral fluorescence lifetime imaging system for intravascular diagnostics with ultrasound guidance: in vivo validation in swine arteries. J Biophotonics. 2014 May; 7(5):281-5. PMID: 23495014.
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    48. Sun Y, Xie H, Liu J, Lam M, Chaudhari AJ, Zhou F, Bec J, Yankelevich DR, Dobbie A, Tinling SL, Gandour-Edwards RF, Monsky WL, Farwell DG, Marcu L. In vivo validation of a bimodal technique combining time-resolved fluorescence spectroscopy and ultrasonic backscatter microscopy for diagnosis of oral carcinoma. J Biomed Opt. 2012 Nov; 17(11):116003. PMID: 23117798.
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    49. Bec J, Xie H, Yankelevich DR, Zhou F, Sun Y, Ghata N, Aldredge R, Marcu L. Design, construction, and validation of a rotary multifunctional intravascular diagnostic catheter combining multispectral fluorescence lifetime imaging and intravascular ultrasound. J Biomed Opt. 2012 Oct; 17(10):106012. PMID: 23224011.
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    50. Roncali E, Phipps JE, Marcu L, Cherry SR. Pulse shape discrimination and classification methods for continuous depth of interaction encoding PET detectors. Phys Med Biol. 2012 Oct 21; 57(20):6571-85. PMID: 23010690.
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    51. Phipps JE, Sun Y, Fishbein MC, Marcu L. A fluorescence lifetime imaging classification method to investigate the collagen to lipid ratio in fibrous caps of atherosclerotic plaque. Lasers Surg Med. 2012 Sep; 44(7):564-71. PMID: 22886522.
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    52. Xie H, Bec J, Liu J, Sun Y, Lam M, Yankelevich DR, Marcu L. Multispectral scanning time-resolved fluorescence spectroscopy (TRFS) technique for intravascular diagnosis. Biomed Opt Express. 2012 Jul 01; 3(7):1521-33. PMID: 22808425.
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    53. Liu J, Sun Y, Qi J, Marcu L. A novel method for fast and robust estimation of fluorescence decay dynamics using constrained least-squares deconvolution with Laguerre expansion. Phys Med Biol. 2012 Feb 21; 57(4):843-65. PMID: 22290334.
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    54. Sun Y, Responte D, Xie H, Liu J, Fatakdawala H, Hu J, Athanasiou KA, Marcu L. Nondestructive evaluation of tissue engineered articular cartilage using time-resolved fluorescence spectroscopy and ultrasound backscatter microscopy. Tissue Eng Part C Methods. 2012 Mar; 18(3):215-26. PMID: 22010819.
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    55. Marcu L. Fluorescence lifetime techniques in medical applications. Ann Biomed Eng. 2012 Feb; 40(2):304-31. PMID: 22273730.
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    56. Marcu L, Hartl BA. Fluorescence Lifetime Spectroscopy and Imaging in Neurosurgery. IEEE J Sel Top Quantum Electron. 2012 Jul-Aug; 18(4):1465-1477. PMID: 28053498.
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    57. Knorr F, Yankelevich DR, Liu J, Wachsmann-Hogiu S, Marcu L. Two-photon excited fluorescence lifetime measurements through a double-clad photonic crystal fiber for tissue micro-endoscopy. J Biophotonics. 2012 Jan; 5(1):14-9. PMID: 22045513.
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    58. Phipps J, Sun Y, Saroufeem R, Hatami N, Fishbein MC, Marcu L. Fluorescence lifetime imaging for the characterization of the biochemical composition of atherosclerotic plaques. J Biomed Opt. 2011 Sep; 16(9):096018. PMID: 21950932.
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    59. Sun Y, Chaudhari AJ, Lam M, Xie H, Yankelevich DR, Phipps J, Liu J, Fishbein MC, Cannata JM, Shung KK, Marcu L. Multimodal characterization of compositional, structural and functional features of human atherosclerotic plaques. Biomed Opt Express. 2011 Aug 01; 2(8):2288-98. PMID: 21833365.
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    60. Phipps JE, Hatami N, Galis ZS, Baker JD, Fishbein MC, Marcu L. A fluorescence lifetime spectroscopy study of matrix metalloproteinases-2 and -9 in human atherosclerotic plaque. J Biophotonics. 2011 Sep; 4(9):650-8. PMID: 21770037.
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    61. Sun Y, Sun Y, Stephens D, Xie H, Phipps J, Saroufeem R, Southard J, Elson DS, Marcu L. Dynamic tissue analysis using time- and wavelength-resolved fluorescence spectroscopy for atherosclerosis diagnosis. Opt Express. 2011 Feb 28; 19(5):3890-901. PMID: 21369214.
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    62. Fite BZ, Decaris M, Sun Y, Sun Y, Lam A, Ho CK, Leach JK, Marcu L. Noninvasive multimodal evaluation of bioengineered cartilage constructs combining time-resolved fluorescence and ultrasound imaging. Tissue Eng Part C Methods. 2011 Apr; 17(4):495-504. PMID: 21303258.
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    63. Butte PV, Mamelak AN, Nuno M, Bannykh SI, Black KL, Marcu L. Fluorescence lifetime spectroscopy for guided therapy of brain tumors. Neuroimage. 2011 Jan; 54 Suppl 1:S125-35. PMID: 21055475.
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    64. Sun Y, Hatami N, Yee M, Phipps J, Elson DS, Gorin F, Schrot RJ, Marcu L. Fluorescence lifetime imaging microscopy for brain tumor image-guided surgery. J Biomed Opt. 2010 Sep-Oct; 15(5):056022. PMID: 21054116.
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    65. Meier JD, Xie H, Sun Y, Sun Y, Hatami N, Poirier B, Marcu L, Farwell DG. Time-resolved laser-induced fluorescence spectroscopy as a diagnostic instrument in head and neck carcinoma. Otolaryngol Head Neck Surg. 2010 Jun; 142(6):838-44. PMID: 20493355.
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    66. Butte PV, Fang Q, Jo JA, Yong WH, Pikul BK, Black KL, Marcu L. Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy. J Biomed Opt. 2010 Mar-Apr; 15(2):027008. PMID: 20459282.
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    67. Farwell DG, Meier JD, Park J, Sun Y, Coffman H, Poirier B, Phipps J, Tinling S, Enepekides DJ, Marcu L. Time-resolved fluorescence spectroscopy as a diagnostic technique of oral carcinoma: Validation in the hamster buccal pouch model. Arch Otolaryngol Head Neck Surg. 2010 Feb; 136(2):126-33. PMID: 20157056.
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    68. Marcu L. Fluorescence lifetime in cardiovascular diagnostics. J Biomed Opt. 2010 Jan-Feb; 15(1):011106. PMID: 20210432.
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    69. Sun Y, Phipps J, Elson DS, Stoy H, Tinling S, Meier J, Poirier B, Chuang FS, Farwell DG, Marcu L. Fluorescence lifetime imaging microscopy: in vivo application to diagnosis of oral carcinoma. Opt Lett. 2009 Jul 01; 34(13):2081-3. PMID: 19572006.
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    70. Sun Y, Park J, Stephens DN, Jo JA, Sun L, Cannata JM, Saroufeem RM, Shung KK, Marcu L. Development of a dual-modal tissue diagnostic system combining time-resolved fluorescence spectroscopy and ultrasonic backscatter microscopy. Rev Sci Instrum. 2009 Jun; 80(6):065104. PMID: 19566223.
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    71. Stephens DN, Park J, Sun Y, Papaioannou T, Marcu L. Intraluminal fluorescence spectroscopy catheter with ultrasound guidance. J Biomed Opt. 2009 May-Jun; 14(3):030505. PMID: 19566287.
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    72. Lo J, Chen SJ, Fang Q, Papaioannou T, Kim ES, Gundersen M, Marcu L. Performance of a diaphragmed microlens for a packaged microspectrometer. Sensors (Basel). 2009; 9(2):859-68. PMID: 22399943.
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    73. Yan J, Sun Y, Zhu H, Marcu L, Revzin A. Enzyme-containing hydrogel micropatterns serving a dual purpose of cell sequestration and metabolite detection. Biosens Bioelectron. 2009 Apr 15; 24(8):2604-10. PMID: 19251408.
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    74. Phipps J, Sun Y, Saroufeem R, Hatami N, Marcu L. Fluorescence lifetime imaging microscopy for the characterization of atherosclerotic plaques. Proc SPIE Int Soc Opt Eng. 2009; 7161:71612G. PMID: 19606277.
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    75. Saxena V, Marcu L, Karunasiri G. A novel noninvasive all optical technique to monitor physiology of an exercising muscle. Phys Med Biol. 2008 Nov 07; 53(21):6211-25. PMID: 18854609.
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    76. Marcu L, Jo JA, Fang Q, Papaioannou T, Reil T, Qiao JH, Baker JD, Freischlag JA, Fishbein MC. Detection of rupture-prone atherosclerotic plaques by time-resolved laser-induced fluorescence spectroscopy. Atherosclerosis. 2009 May; 204(1):156-64. PMID: 18926540.
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    77. Sun Y, Liu R, Elson DS, Hollars CW, Jo JA, Park J, Sun Y, Marcu L. Simultaneous time- and wavelength-resolved fluorescence spectroscopy for near real-time tissue diagnosis. Opt Lett. 2008 Mar 15; 33(6):630-2. PMID: 18347733.
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    78. Liao KC, Hogen-Esch T, Richmond FJ, Marcu L, Clifton W, Loeb GE. Percutaneous fiber-optic sensor for chronic glucose monitoring in vivo. Biosens Bioelectron. 2008 May 15; 23(10):1458-65. PMID: 18304798.
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    79. Sun Y, Stephens DN, Park J, Sun Y, Marcu L, Cannata JM, Shung KK. Development of a Multi-modal Tissue Diagnostic System Combining High Frequency Ultrasound and Photoacoustic Imaging with Lifetime Fluorescence Spectroscopy. Proc IEEE Ultrason Symp. 2008; 570-573. PMID: 21894259.
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    80. Garon EB, Sawcer D, Vernier PT, Tang T, Sun Y, Marcu L, Gundersen MA, Koeffler HP. In vitro and in vivo evaluation and a case report of intense nanosecond pulsed electric field as a local therapy for human malignancies. Int J Cancer. 2007 Aug 01; 121(3):675-82. PMID: 17417774.
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    81. Wang J, Yong WH, Sun Y, Vernier PT, Koeffler HP, Gundersen MA, Marcu L. Receptor-targeted quantum dots: fluorescent probes for brain tumor diagnosis. J Biomed Opt. 2007 Jul-Aug; 12(4):044021. PMID: 17867825.
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    82. Jo JA, Marcu L, Fang Q, Papaioannou T, Qiao JH, Fishbein MC, Beseth B, Dorafshar AH, Reil T, Baker D, Freischlag J. New methods for time-resolved fluorescence spectroscopy data analysis based on the Laguerre expansion technique--applications in tissue diagnosis. Methods Inf Med. 2007; 46(2):206-11. PMID: 17347757.
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    83. Garon EB, Marcu L, Luong Q, Tcherniantchouk O, Crooks GM, Koeffler HP. Quantum dot labeling and tracking of human leukemic, bone marrow and cord blood cells. Leuk Res. 2007 May; 31(5):643-51. PMID: 17027955.
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    84. Yong WH, Butte PV, Pikul BK, Jo JA, Fang Q, Papaioannou T, Black K, Marcu L. Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy. Front Biosci. 2006 May 01; 11:1255-63. PMID: 16368511.
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    85. Sun Y, Vernier PT, Behrend M, Wang J, Thu MM, Gundersen M, Marcu L. Fluorescence microscopy imaging of electroperturbation in mammalian cells. J Biomed Opt. 2006 Mar-Apr; 11(2):024010. PMID: 16674200.
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    86. Jo JA, Fang Q, Papaioannou T, Baker JD, Dorafshar AH, Reil T, Qiao JH, Fishbein MC, Freischlag JA, Marcu L. Laguerre-based method for analysis of time-resolved fluorescence data: application to in-vivo characterization and diagnosis of atherosclerotic lesions. J Biomed Opt. 2006 Mar-Apr; 11(2):021004. PMID: 16674179.
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    87. Jo JA, Fang Q, Papaioannou T, Qiao JH, Fishbein MC, Beseth B, Dorafshar AH, Reil T, Baker D, Freischlag J, Shung KK, Sun L, Marcu L. Diagnosis of vulnerable atherosclerotic plaques by time-resolved fluorescence spectroscopy and ultrasound imaging. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:2663-6. PMID: 17946129.
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    88. Sun Y, Vernier PT, Behrend M, Marcu L, Gundersen MA. Electrode microchamber for noninvasive perturbation of mammalian cells with nanosecond pulsed electric fields. IEEE Trans Nanobioscience. 2005 Dec; 4(4):277-83. PMID: 16433293.
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    89. Butte PV, Pikul BK, Hever A, Yong WH, Black KL, Marcu L. Diagnosis of meningioma by time-resolved fluorescence spectroscopy. J Biomed Opt. 2005 Nov-Dec; 10(6):064026. PMID: 16409091.
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    90. Rouhanizadeh M, Hwang J, Clempus RE, Marcu L, Lassègue B, Sevanian A, Hsiai TK. Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase. Free Radic Biol Med. 2005 Dec 01; 39(11):1512-22. PMID: 16274886.
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    91. Marcu L, Fang Q, Jo JA, Papaioannou T, Dorafshar A, Reil T, Qiao JH, Baker JD, Freischlag JA, Fishbein MC. In vivo detection of macrophages in a rabbit atherosclerotic model by time-resolved laser-induced fluorescence spectroscopy. Atherosclerosis. 2005 Aug; 181(2):295-303. PMID: 16039283.
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    92. Ivanova OV, Marcu L, Khoo MC. A nonparametric method for analysis of fluorescence emission in combined time and wavelength dimensions. Ann Biomed Eng. 2005 Apr; 33(4):531-44. PMID: 15909659.
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    93. Jo JA, Fang Q, Marcu L. Ultrafast Method for the Analysis of Fluorescence Lifetime Imaging Microscopy Data Based on the Laguerre Expansion Technique. IEEE J Quantum Electron. 2005; 11(4):835-845. PMID: 19444338.
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    94. Vernier PT, Sun Y, Wang J, Thu MM, Garon E, Valderrabano M, Marcu L, Koeffler HP, Gundersen MA. Nanoelectropulse intracellular perturbation and electropermeabilization technology: phospholipid translocation, calcium bursts, chromatin rearrangement, cardiomyocyte activation, and tumor cell sensitivity. Conf Proc IEEE Eng Med Biol Soc. 2005; 6:5850-3. PMID: 17281590.
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    95. Vernier PT, Sun Y, Marcu L, Craft CM, Gundersen MA. Nanosecond pulsed electric fields perturb membrane phospholipids in T lymphoblasts. FEBS Lett. 2004 Aug 13; 572(1-3):103-8. PMID: 15304332.
      View in: PubMed
    96. Marcu L, Jo JA, Butte PV, Yong WH, Pikul BK, Black KL, Thompson RC. Fluorescence lifetime spectroscopy of glioblastoma multiforme. Photochem Photobiol. 2004 Jul-Aug; 80:98-103. PMID: 15339216.
      View in: PubMed
    97. Jo JA, Fang Q, Papaioannou T, Marcu L. Fast model-free deconvolution of fluorescence decay for analysis of biological systems. J Biomed Opt. 2004 Jul-Aug; 9(4):743-52. PMID: 15250761.
      View in: PubMed
    98. Vernier PT, Sun Y, Marcu L, Craft CM, Gundersen MA. Nanoelectropulse-induced phosphatidylserine translocation. Biophys J. 2004 Jun; 86(6):4040-8. PMID: 15189899.
      View in: PubMed
    99. Papaioannou T, Preyer NW, Fang Q, Brightwell A, Carnohan M, Cottone G, Ross R, Jones LR, Marcu L. Effects of fiber-optic probe design and probe-to-target distance on diffuse reflectance measurements of turbid media: an experimental and computational study at 337 nm. Appl Opt. 2004 May 10; 43(14):2846-60. PMID: 15143808.
      View in: PubMed
    100. Ashjian P, Elbarbary A, Zuk P, DeUgarte DA, Benhaim P, Marcu L, Hedrick MH. Noninvasive in situ evaluation of osteogenic differentiation by time-resolved laser-induced fluorescence spectroscopy. Tissue Eng. 2004 Mar-Apr; 10(3-4):411-20. PMID: 15165458.
      View in: PubMed
    101. Chih Liao K, Richmond F, Hogen-Esch T, Marcu L, Loeb GE. Senciltrade mark project: development of a percutaneous optical biosensor. Conf Proc IEEE Eng Med Biol Soc. 2004; 3:2082-5. PMID: 17272132.
      View in: PubMed
    102. Vernier PT, Sun Y, Marcu L, Salemi S, Craft CM, Gundersen MA. Calcium bursts induced by nanosecond electric pulses. Biochem Biophys Res Commun. 2003 Oct 17; 310(2):286-95. PMID: 14521908.
      View in: PubMed
    103. Marcu L, Fishbein MC, Maarek JM, Grundfest WS. Discrimination of human coronary artery atherosclerotic lipid-rich lesions by time-resolved laser-induced fluorescence spectroscopy. Arterioscler Thromb Vasc Biol. 2001 Jul; 21(7):1244-50. PMID: 11451759.
      View in: PubMed
    104. Maarek JM, Marcu L, Snyder WJ, Grundfest WS. Time-resolved fluorescence spectra of arterial fluorescent compounds: reconstruction with the Laguerre expansion technique. Photochem Photobiol. 2000 Feb; 71(2):178-87. PMID: 10687392.
      View in: PubMed
    105. Maarek JM, Marcu L, Fishbein MC, Grundfest WS. Time-resolved fluorescence of human aortic wall: use for improved identification of atherosclerotic lesions. Lasers Surg Med. 2000; 27(3):241-54. PMID: 11013386.
      View in: PubMed
    106. Marcu L, Grundfest WS, Maarek JM. Photobleaching of arterial fluorescent compounds: characterization of elastin, collagen and cholesterol time-resolved spectra during prolonged ultraviolet irradiation. Photochem Photobiol. 1999 Jun; 69(6):713-21. PMID: 10378012.
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