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Roger Sciammas, PhD

Title(s)Assistant Professor, School of Veterinary Medicine
SchoolUniversity of California, Davis
AddressCA 95616
Phone530-754-4419
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. PLoS One. 2020; 15(7):e0235518. Choi JW, Withers SS, Chang H, Spanier JA, De La Trinidad VL, Panesar H, Fife BT, Sciammas R, Sparger EE, Moore PF, Kent MS, Rebhun RB, McSorley SJ. PMID: 32614928.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020 Jul 01; 130(7):3453-3466. Khiew SH, Jain D, Chen J, Yang J, Yin D, Young JS, Dent A, Sciammas R, Alegre ML, Chong AS. PMID: 32452834.
      View in: PubMed   Mentions: 1     Fields:    
    3. A Synchronous IRF4-Dependent Gene Regulatory Network in B and Helper T Cells Orchestrating the Antibody Response. Trends Immunol. 2020 Jul; 41(7):614-628. Cook SL, Franke MC, Sievert EP, Sciammas R. PMID: 32467029.
      View in: PubMed   Mentions:    Fields:    
    4. Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses. Elife. 2020 Feb 04; 9. Lee J, Zhang J, Chung YJ, Kim JH, Kook CM, González-Navajas JM, Herdman DS, Nürnberg B, Insel PA, Corr M, Mo JH, Tao A, Yasuda K, Rifkin IR, Broide DH, Sciammas R, Webster NJ, Raz E. PMID: 32014112.
      View in: PubMed   Mentions: 1     Fields:    
    5. Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction. Immunity. 2017 12 19; 47(6):1114-1128.e6. Wu J, Zhang H, Shi X, Xiao X, Fan Y, Minze LJ, Wang J, Ghobrial RM, Xia J, Sciammas R, Li XC, Chen W. PMID: 29221730.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    6. Igß ubiquitination activates PI3K signals required for endosomal sorting. J Exp Med. 2017 Dec 04; 214(12):3775-3790. Veselits M, Tanaka A, Chen Y, Hamel K, Mandal M, Kandasamy M, Manicassamy B, O'Neill SK, Wilson P, Sciammas R, Clark MR. PMID: 29141870.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice. Front Immunol. 2017; 8:1169. Young JS, Khiew SH, Yang J, Vannier A, Yin D, Sciammas R, Alegre ML, Chong AS. PMID: 28970838.
      View in: PubMed   Mentions: 2     Fields:    
    8. The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate. Immunity. 2017 09 19; 47(3):481-497.e7. Krishnamoorthy V, Kannanganat S, Maienschein-Cline M, Cook SL, Chen J, Bahroos N, Sievert E, Corse E, Chong A, Sciammas R. PMID: 28930660.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. CTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients. JCI Insight. 2017 May 04; 2(9). Khiew SH, Yang J, Young JS, Chen J, Wang Q, Yin D, Vu V, Miller ML, Sciammas R, Alegre ML, Chong AS. PMID: 28469082.
      View in: PubMed   Mentions: 2     Fields:    
    10. Tracing Donor-MHC Class II Reactive B cells in Mouse Cardiac Transplantation: Delayed CTLA4-Ig Treatment Prevents Memory Alloreactive B-Cell Generation. Transplantation. 2016 08; 100(8):1683-91. Yang J, Chen J, Young JS, Wang Q, Yin D, Sciammas R, Chong AS. PMID: 27362308.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    11. Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection. Am J Transplant. 2016 08; 16(8):2312-23. Young JS, Chen J, Miller ML, Vu V, Tian C, Moon JJ, Alegre ML, Sciammas R, Chong AS. PMID: 26928966.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    12. Cutting Edge: CTLA-4Ig Inhibits Memory B Cell Responses and Promotes Allograft Survival in Sensitized Recipients. J Immunol. 2015 Nov 01; 195(9):4069-73. Chen J, Wang Q, Yin D, Vu V, Sciammas R, Chong AS. PMID: 26416270.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    13. Memory B cells in transplantation. Transplantation. 2015 Jan; 99(1):21-8. Chong AS, Sciammas R. PMID: 25525921.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    14. Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients. Transplantation. 2014 Apr 27; 97(8):846-53. Cowan M, Chon WJ, Desai A, Andrews S, Bai Y, Veguilla V, Katz JM, Josephson MA, Wilson PC, Sciammas R, Chong AS. PMID: 24366008.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes. PLoS One. 2014; 9(3):e89792. Veselits M, Tanaka A, Lipkowitz S, O'Neill S, Sciammas R, Finnegan A, Zhang J, Clark MR. PMID: 24651487.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation. Biomaterials. 2013 Nov; 34(34):8776-85. Chen J, Pompano RR, Santiago FW, Maillat L, Sciammas R, Sun T, Han H, Topham DJ, Chong AS, Collier JH. PMID: 23953841.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    17. Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig. Am J Transplant. 2013 Sep; 13(9):2280-92. Chen J, Yin H, Xu J, Wang Q, Edelblum KL, Sciammas R, Chong AS. PMID: 23855587.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    18. B cells assist allograft rejection in the deficiency of protein kinase c-theta. Transpl Int. 2013 Sep; 26(9):919-27. Yan W, Xu R, Ma LL, Han W, Geevarghese SK, Williams PE, Sciammas R, Chong AS, Yin DP. PMID: 23841454.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    19. Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity. 2013 May 23; 38(5):918-29. Ochiai K, Maienschein-Cline M, Simonetti G, Chen J, Rosenthal R, Brink R, Chong AS, Klein U, Dinner AR, Singh H, Sciammas R. PMID: 23684984.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    20. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nat Commun. 2013; 4:2990. Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. PMID: 24356538.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    21. Plasma cell densities and glomerular filtration rates predict renal allograft outcomes following acute rejection. Transpl Int. 2012 Oct; 25(10):1050-8. Chang A, Moore JM, Cowan ML, Josephson MA, Chon WJ, Sciammas R, Du Z, Marino SR, Meehan SM, Millis M, David MZ, Williams JW, Chong AS. PMID: 22805456.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol. 2012 Jan 22; 13(3):300-7. Ochiai K, Maienschein-Cline M, Mandal M, Triggs JR, Bertolino E, Sciammas R, Dinner AR, Clark MR, Singh H. PMID: 22267219.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    23. IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood. 2012 Mar 01; 119(9):2003-12. Becker AM, Michael DG, Satpathy AT, Sciammas R, Singh H, Bhattacharya D. PMID: 22238324.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    24. Discovering transcription factor regulatory targets using gene expression and binding data. Bioinformatics. 2012 Jan 15; 28(2):206-13. Maienschein-Cline M, Zhou J, White KP, Sciammas R, Dinner AR. PMID: 22084256.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    25. Matchmaking the B-cell signature of tolerance to regulatory B cells. Am J Transplant. 2011 Dec; 11(12):2555-60. Chong AS, Sciammas R. PMID: 21967001.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    26. Experimental models of B cell tolerance in transplantation. Semin Immunol. 2012 Apr; 24(2):77-85. Cowan ML, Sciammas R, Chong AS. PMID: 21925896.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    27. An incoherent regulatory network architecture that orchestrates B cell diversification in response to antigen signaling. Mol Syst Biol. 2011 May 24; 7:495. Sciammas R, Li Y, Warmflash A, Song Y, Dinner AR, Singh H. PMID: 21613984.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    28. The B Cell Response to Transplantation Antigens. . 2010 Apr 16; 38-53. Roger Sciammas, Anita S. Chong, Robert B. Colvin. .
      View in: Publisher Site   Mentions:
    29. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 2006 Aug 25; 126(4):755-66. Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H. PMID: 16923394.
      View in: PubMed   Mentions: 228     Fields:    Translation:AnimalsCells
    30. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity. 2006 Aug; 25(2):225-36. Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, Singh H. PMID: 16919487.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    31. Shedding B cell identity. Immunity. 2006 Mar; 24(3):239-40. Singh H, Sciammas R. PMID: 16546090.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    32. The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development. 2005 Mar; 132(6):1315-25. Vincent SD, Dunn NR, Sciammas R, Shapiro-Shalef M, Davis MM, Calame K, Bikoff EK, Robertson EJ. PMID: 15750184.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    33. Blimp-1; immunoglobulin secretion and the switch to plasma cells. Curr Top Microbiol Immunol. 2005; 290:201-24. Sciammas R, Davis MM. PMID: 16480044.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    34. Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation. J Immunol. 2004 May 01; 172(9):5427-40. Sciammas R, Davis MM. PMID: 15100284.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    35. TCRgammadelta cells and viruses. Microbes Infect. 1999 Mar; 1(3):203-12. Sciammas R, Bluestone JA. PMID: 10801231.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    36. HSV-1 glycoprotein I-reactive TCR gamma delta cells directly recognize the peptide backbone in a conformationally dependent manner. J Immunol. 1998 Nov 15; 161(10):5187-92. Sciammas R, Bluestone JA. PMID: 9820489.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    37. T cell receptor-gamma/delta cells protect mice from herpes simplex virus type 1-induced lethal encephalitis. J Exp Med. 1997 Jun 02; 185(11):1969-75. Sciammas R, Kodukula P, Tang Q, Hendricks RL, Bluestone JA. PMID: 9166426.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    38. TCR gamma delta cells: a specialized T-cell subset in the immune system. Annu Rev Cell Dev Biol. 1995; 11:307-53. Bluestone JA, Khattri R, Sciammas R, Sperling AI. PMID: 8689560.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    39. Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell. J Immunol. 1994 Jun 01; 152(11):5392-7. Sciammas R, Johnson RM, Sperling AI, Brady W, Linsley PS, Spear PG, Fitch FW, Bluestone JA. PMID: 8189058.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    40. TCR gamma delta cells: mysterious cells of the immune system. Immunol Res. 1994; 13(4):268-79. Sciammas R, Tatsumi Y, Sperling AI, Arunan K, Bluestone JA. PMID: 7616054.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells