Janai R Carr-Ascher

Title(s)Assistant Professor, MED: Int Med Hematology/Oncology
SchoolSchool of Medicine
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    Title(s)Assistant Professor in Residence, MED: Int Med Hematology/Oncology

    Title(s)Assistant Professor in Residence, MED: Orthopaedic Surgery


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genetic Screen in a Preclinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities. Clin Cancer Res. 2024 Nov 01; 30(21):4957-4973. Freeland J, Muñoz M, O'Donnell E, Langerman J, Darrow M, Bergonio J, Suarez-Navarro J, Thorpe S, Canter R, Randall RL, Plath K, Carraway KL, Witte ON, Graeber TG, Carr-Ascher JR. PMID: 39177582; PMCID: PMC11530313.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Genetic and Epigenetic Characterization of Sarcoma Stem Cells Across Subtypes Identifies EZH2 as a Therapeutic Target. bioRxiv. 2024 May 14. O'Donnell E, Muñoz M, Davis R, Randall RL, Tepper C, Carr-Ascher J. PMID: 38798385; PMCID: PMC11118861.
      View in: PubMed   Mentions:
    3. Emerging innovations and advancements in the treatment of extremity and truncal soft tissue sarcomas. J Surg Oncol. 2024 Jan; 129(1):97-111. Walker K, Simister SK, Carr-Ascher J, Monument MJ, Thorpe SW, Randall RL. PMID: 38010997.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Scrutinizing the use of contrasted chest CTs in extremity sarcoma staging and surveillance. J Surg Oncol. 2024 Mar; 129(3):523-530. Priester JI, Simister SK, Sario M, Choi J, Pina D, Theriault R, Bateni C, Ghasemiesfe A, Carr-Ascher J, Monjazeb AM, Canter RJ, Randall RL, Thorpe SW. PMID: 37997294.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Wild-type C-Raf gene dosage and dimerization drive prostate cancer metastasis. iScience. 2023 Dec 15; 26(12):108480. Ta L, Tsai BL, Deng W, Sha J, Varuzhanyan G, Tran W, Wohlschlegel JA, Carr-Ascher JR, Witte ON. PMID: 38089570; PMCID: PMC10711388.
      View in: PubMed   Mentions:
    6. Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis. J Immunother Cancer. 2023 01; 11(1). Perry LM, Cruz SM, Kleber KT, Judge SJ, Darrow MA, Jones LB, Basmaci UN, Joshi N, Settles ML, Durbin-Johnson BP, Gingrich AA, Monjazeb AM, Carr-Ascher J, Thorpe SW, Murphy WJ, Eisen JA, Canter RJ. PMID: 36599469; PMCID: PMC9815021.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    7. Case report: Treatment of metastatic dedifferentiated chondrosarcoma with pembrolizumab yields sustained complete response. Front Oncol. 2022; 12:991724. Singh A, Thorpe SW, Darrow M, Carr-Ascher JR. PMID: 36465334; PMCID: PMC9713241.
      View in: PubMed   Mentions: 4  
    8. Correction to: ASO Author Reflections: Insurance-Related Disparities in High Grade Bone Sarcoma of Lower Extremity. Ann Surg Oncol. 2022 Nov; 29(12):7353. Jawad MU, Pollock BH, Alvarez E, Carr-Ascher JR, Randall RL, Thorpe SW. PMID: 35428963.
      View in: PubMed   Mentions:    Fields:    
    9. NCCN Guidelines® Insights: Gastrointestinal Stromal Tumors, Version 2.2022. J Natl Compr Canc Netw. 2022 11; 20(11):1204-1214. von Mehren M, Kane JM, Riedel RF, Sicklick JK, Pollack SM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Poppe M, Schuetze S, Shabason J, Spraker MB, Zimel M, Bergman MA, Sundar H, Hang LE. PMID: 36351335; PMCID: PMC10245542.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    10. Correction to: Non-Private Health Insurance Predicts Advanced Stage at Presentation and Amputation in Lower Extremity High Grade Bone Sarcoma: A National Cancer Database Study. Ann Surg Oncol. 2022 Oct; 29(11):7134. Jawad MU, Pollock BH, Alvarez E, Carr-Ascher JR, Randall RL, Thorpe SW. PMID: 35428962.
      View in: PubMed   Mentions:    Fields:    
    11. Socioeconomic and insurance-related disparities in disease-specific survival among patients with metastatic bone disease. J Surg Oncol. 2023 Jan; 127(1):159-173. Jawad MU, Pollock BH, Wise BL, Zeitlinger LN, O' Donnell EF, Carr-Ascher JR, Cizik A, Ferrell B, Thorpe SW, Randall RL. PMID: 36121418.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Head and Neck Cutaneous Soft-Tissue Sarcoma Demonstrate Sex and Racial/Ethnic Disparities in Incidence and Socioeconomic Disparities in Survival. J Clin Med. 2022 Sep 17; 11(18). Jawad MU, Zeitlinger LN, Bewley AF, O'Donnell EF, Traven SA, Carr-Ascher JR, Monjazeb AM, Canter RJ, Thorpe SW, Randall RL. PMID: 36143122; PMCID: PMC9501210.
      View in: PubMed   Mentions:
    13. Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022 07; 20(7):815-833. von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA. PMID: 35830886; PMCID: PMC10186762.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    14. Impact of local treatment modality on overall- and disease-specific survival for nonmetastatic pelvic and sacral Ewing sarcoma. J Surg Oncol. 2022 Sep; 126(3):577-587. Jawad MU, Pollock BH, Zeitlinger LN, O'Donnell EF, Traven SA, Carr-Ascher JR, Alvarez E, Malogolowkin MH, Thorpe SW, Randall RL. PMID: 35585834.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Non-Private Health Insurance Predicts Advanced Stage at Presentation and Amputation in Lower Extremity High Grade Bone Sarcoma: A National Cancer Database Study : Amputation Predicts Survival: An Effect Most Pronounced in Pediatric and AYA Age Group. Ann Surg Oncol. 2022 Mar 21. Jawad MU, Pollock BH, Alvarez E, Carr-Ascher JR, Randall RL, Thorpe SW. PMID: 35314919.
      View in: PubMed   Mentions: 1     Fields:    
    16. ASO Author Reflections: Insurance-Related Disparities in High Grade Bone Sarcoma of Lower Extremity. Ann Surg Oncol. 2022 Mar 13. Jawad MU, Pollock BH, Alvarez E, Carr-Ascher JR, Randall RL, Thorpe SW. PMID: 35284977.
      View in: PubMed   Mentions:    Fields:    
    17. Sex, racial/ethnic and socioeconomic disparities in patients with metastatic bone disease. J Surg Oncol. 2022 Mar; 125(4):766-774. Jawad MU, Pollock BH, Wise BL, Zeitlinger LN, O' Donnell EF, Carr-Ascher JR, Cizik A, Ferrell B, Thorpe SW, Randall RL. PMID: 34889456; PMCID: PMC9204646.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review. J Surg Oncol. 2021 Dec; 124(8):1515-1522. Jawad MU, Bayne CO, Farhan S, Haffner MR, Carr-Ascher J, Alvarez E, Thorpe SW, Randall RL. PMID: 34432316; PMCID: PMC9987264.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Author Correction: Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein. Sci Rep. 2018 Oct 29; 8(1):15850. Mukhopadhyay NK, Chand V, Pandey A, Kopanja D, Carr JR, Chen YJ, Liao X, Raychaudhuri P. PMID: 30374061; PMCID: PMC6206056.
      View in: PubMed   Mentions:    Fields:    
    20. Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein. Sci Rep. 2017 04 07; 7:46017. Mukhopadhyay NK, Chand V, Pandey A, Kopanja D, Carr JR, Chen YJ, Liao X, Raychaudhuri P. PMID: 28387346; PMCID: PMC5384083.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    21. Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features. J Hepatol. 2015 Aug; 63(2):429-36. Kopanja D, Pandey A, Kiefer M, Wang Z, Chandan N, Carr JR, Franks R, Yu DY, Guzman G, Maker A, Raychaudhuri P. PMID: 25828473; PMCID: PMC4508215.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    22. Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma. Mol Cancer Ther. 2013 May; 12(5):759-67. Wang Z, Zheng Y, Park HJ, Li J, Carr JR, Chen YJ, Kiefer MM, Kopanja D, Bagchi S, Tyner AL, Raychaudhuri P. PMID: 23427295; PMCID: PMC3651795.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    23. FoxM1 regulates mammary luminal cell fate. Cell Rep. 2012 Jun 28; 1(6):715-29. Carr JR, Kiefer MM, Park HJ, Li J, Wang Z, Fontanarosa J, DeWaal D, Kopanja D, Benevolenskaya EV, Guzman G, Raychaudhuri P. PMID: 22813746; PMCID: PMC3401379.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    24. FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors. Cancer Res. 2011 Jun 15; 71(12):4292-302. Wang Z, Park HJ, Carr JR, Chen YJ, Zheng Y, Li J, Tyner AL, Costa RH, Bagchi S, Raychaudhuri P. PMID: 21507930; PMCID: PMC3771352.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    25. Deregulation of FoxM1b leads to tumour metastasis. EMBO Mol Med. 2011 Jan; 3(1):21-34. Park HJ, Gusarova G, Wang Z, Carr JR, Li J, Kim KH, Qiu J, Park YD, Williamson PR, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. PMID: 21204266; PMCID: PMC3401999.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    26. FoxM1 mediates resistance to herceptin and paclitaxel. Cancer Res. 2010 Jun 15; 70(12):5054-63. Carr JR, Park HJ, Wang Z, Kiefer MM, Raychaudhuri P. PMID: 20530690; PMCID: PMC2893542.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    27. Modulating temporal and spatial oxygenation over adherent cellular cultures. PLoS One. 2009 Sep 03; 4(9):e6891. Oppegard SC, Nam KH, Carr JR, Skaalure SC, Eddington DT. PMID: 19727397; PMCID: PMC2731542.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    28. FoxM1, a critical regulator of oxidative stress during oncogenesis. EMBO J. 2009 Oct 07; 28(19):2908-18. Park HJ, Carr JR, Wang Z, Nogueira V, Hay N, Tyner AL, Lau LF, Costa RH, Raychaudhuri P. PMID: 19696738; PMCID: PMC2760115.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    29. Immunity to growth factor receptor-bound protein 10, a signal transduction molecule, inhibits the growth of breast cancer in mice. Cancer Res. 2008 Apr 01; 68(7):2463-70. O-Sullivan I, Chopra A, Carr J, Kim TS, Cohen EP. PMID: 18381455.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. T-regulatory cells are relatively deficient in squamous carcinomas undergoing regression in mice immunized with a squamous carcinoma vaccine enriched for immunotherapeutic cells. Cancer Gene Ther. 2007 Jun; 14(6):573-82. Chopra A, O-Sullivan I, Carr J, Kim TS, Cohen EP. PMID: 17384578.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    31. Nonconsensus intronic mutations cause episodic ataxia. Ann Neurol. 2005 Jan; 57(1):131-5. Wan J, Carr JR, Baloh RW, Jen JC. PMID: 15622542.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    32. Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis. Science. 2004 Jun 04; 304(5676):1509-13. Jen JC, Chan WM, Bosley TM, Wan J, Carr JR, Rüb U, Shattuck D, Salamon G, Kudo LC, Ou J, Lin DD, Salih MA, Kansu T, Al Dhalaan H, Al Zayed Z, MacDonald DB, Stigsby B, Plaitakis A, Dretakis EK, Gottlob I, Pieh C, Traboulsi EI, Wang Q, Wang L, Andrews C, Yamada K, Demer JL, Karim S, Alger JR, Geschwind DH, Deller T, Sicotte NL, Nelson SF, Baloh RW, Engle EC. PMID: 15105459; PMCID: PMC1618874.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansCells
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