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Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation. Elife. 2022 10 10; 11.
Merour E, Hmidan H, Marie C, Helou PH, Lu H, Potel A, Hure JB, Clavairoly A, Shih YP, Goudarzi S, Dussaud S, Ravassard P, Hafizi S, Lo SH, Hassan BA, Parras C. PMID: 36214451; PMCID: PMC9596163.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Tensins - emerging insights into their domain functions, biological roles and disease relevance. J Cell Sci. 2021 02 17; 134(4).
Liao YC, Lo SH. PMID: 33597154.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Direct Observations of Silver Nanowire-Induced Frustrated Phagocytosis among NR8383 Lung Alveolar Macrophages. J Phys Chem B. 2020 12 24; 124(51):11584-11592.
Ogorodnik E, Karsai A, Wang KH, Liu FT, Lo SH, Pinkerton KE, Gilbert B, Haudenschild DR, Liu GY. PMID: 33306381; PMCID: PMC7869824.
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PubMed Mentions: Fields:
Translation:
Cells
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Endothelial DLC1 is dispensable for liver and kidney function in mice. Genes Dis. 2022 May; 9(3):814-819.
Tan Y, Lo SH. PMID: 35782987; PMCID: PMC9243348.
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PubMed Mentions:
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Tensin regulates pharyngeal pumping in Caenorhabditis elegans. Biochem Biophys Res Commun. 2020 02 12; 522(3):599-603.
Bruns AN, Lo SH. PMID: 31784086; PMCID: PMC6981048.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Hyperactivity of Mek in TNS1 knockouts leads to potential treatments for cystic kidney diseases. Cell Death Dis. 2019 11 18; 10(12):871.
Wu ZY, Chiu CL, Lo E, Lee YJ, Yamada S, Lo SH. PMID: 31740667; PMCID: PMC6861224.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Force-induced recruitment of cten along keratin network in epithelial cells. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):19799-19801.
Cheah JS, Jacobs KA, Heinrich V, Lo SH, Yamada S. PMID: 31527270; PMCID: PMC6778260.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Identification of subcellular targeting sequences of Cten reveals its role in cell proliferation. Biochim Biophys Acta Mol Cell Res. 2019 03; 1866(3):450-458.
Hong SY, Shih YP, Lo A, Lo SH. PMID: 30321615; PMCID: PMC6311424.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Corrigendum to "Tensin1 positively regulates RhoA activity through its interaction with DLC1" [Biochimica et Biophysica Acta 1853/12 (2015) 3258-3265]. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1383.
Shih YP, Sun P, Wang A, Lo SH. PMID: 29866430.
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PubMed Mentions:
1 Fields:
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Tensins. Curr Biol. 2017 May 08; 27(9):R331-R332.
Lo SH. PMID: 28486112.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process. Cancer Lett. 2017 07 10; 398:46-51.
Shih YP, Yuan SY, Lo SH. PMID: 28408355; PMCID: PMC5460982.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers. Oncotarget. 2016 Jun 21; 7(25):38143-38153.
Hong SY, Shih YP, Sun P, Hsieh WJ, Lin WC, Lo SH. PMID: 27203214; PMCID: PMC5122378.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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?Np63a Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion. PLoS One. 2016; 11(1):e0147542.
Yang K, Wu WM, Chen YC, Lo SH, Liao YC. PMID: 26784942; PMCID: PMC4718700.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Tensin1 positively regulates RhoA activity through its interaction with DLC1. Biochim Biophys Acta. 2015 Dec; 1853(12):3258-65.
Shih YP, Sun P, Wang A, Lo SH. PMID: 26427649; PMCID: PMC4621260.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct; 47(10):1206-11.
Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, PROMESA investigators, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, MVP-France, Jeunemaitre X, Leducq Transatlantic MITRAL Network. PMID: 26301497; PMCID: PMC4773907.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimals
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C-terminal tensin-like (CTEN): a promising biomarker and target for cancer. Int J Biochem Cell Biol. 2014 Jun; 51:150-4.
Lo SH. PMID: 24735711; PMCID: PMC4038153.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation. Cancer Res. 2013 Aug 15; 73(16):5266-76.
Hong SY, Shih YP, Li T, Carraway KL, Lo SH. PMID: 23774213; PMCID: PMC3745516.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R. J Biol Chem. 2013 Jul 05; 288(27):19593-603.
Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y. PMID: 23696648; PMCID: PMC3707660.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Up-regulated cten by FGF2 contributes to FGF2-mediated cell migration. Mol Carcinog. 2014 Oct; 53(10):787-92.
Hung SY, Shih YP, Chen M, Lo SH. PMID: 23625726; PMCID: PMC4388201.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene. Gene. 2013 May 15; 520(2):90-7.
Chen NT, Kuwabara Y, Conley C, Liao YC, Hong SY, Chen M, Shih YP, Chen HW, Hsieh F, Lo SH. PMID: 23500447; PMCID: PMC3627739.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Nanogratings of fibronectin provide an effective biochemical cue for regulating focal adhesion and cellular structure. Nano Research. 2012 Aug 1; 5(8):565-575.
Shi SL, Li LJ, Shih SY, Lo LS, Liu LG. .
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Nanostructures of designed geometry and functionality enable regulation of cellular signaling processes. Biochemistry. 2012 Jul 31; 51(30):5876-93.
Li JR, Shi L, Deng Z, Lo SH, Liu GY. PMID: 22783801; PMCID: PMC4041195.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells. Mol Cancer Res. 2012 Jan; 10(1):34-9.
Shih YP, Takada Y, Lo SH. PMID: 22064653; PMCID: PMC3262057.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer. Oncogene. 2011 Jun 30; 30(26):2997-3002.
Albasri A, Al-Ghamdi S, Fadhil W, Aleskandarany M, Liao YC, Jackson D, Lobo DN, Lo SH, Kumari R, Durrant L, Watson S, Kindle KB, Ilyas M. PMID: 21339732.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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DLC1 negatively regulates angiogenesis in a paracrine fashion. Cancer Res. 2010 Nov 01; 70(21):8270-5.
Shih YP, Liao YC, Lin Y, Lo SH. PMID: 20861185; PMCID: PMC2970702.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. Oncogene. 2010 May 20; 29(20):3010-6.
Lin Y, Chen NT, Shih YP, Liao YC, Xue L, Lo SH. PMID: 20208559; PMCID: PMC2874629.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer. 2010 Jan; 1(1):40-9.
Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, Kung HJ. PMID: 20811583; PMCID: PMC2930266.
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PubMed Mentions:
89
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Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin. Cancer Res. 2009 Jun 01; 69(11):4563-6.
Liao YC, Chen NT, Shih YP, Dong Y, Lo SH. PMID: 19487278; PMCID: PMC2692076.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Conditional loss of PTEN leads to skeletal abnormalities and lipoma formation. Mol Carcinog. 2009 Jun; 48(6):545-52.
Hsieh SC, Chen NT, Lo SH. PMID: 18973188.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Cell tracing dyes significantly change single cell mechanics. J Phys Chem B. 2009 May 07; 113(18):6511-9.
Lulevich V, Shih YP, Lo SH, Liu GY. PMID: 19366241; PMCID: PMC2698996.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Mutations in the focal adhesion targeting region of deleted in liver cancer-1 attenuate their expression and function. Cancer Res. 2008 Oct 01; 68(19):7718-22.
Liao YC, Shih YP, Lo SH. PMID: 18829524; PMCID: PMC2597479.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Nat Cell Biol. 2007 Aug; 9(8):961-9.
Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. PMID: 17643115.
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PubMed Mentions:
84 Fields:
Translation:
HumansCells
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Deleted in liver cancer-1 (DLC-1): a tumor suppressor not just for liver. Int J Biochem Cell Biol. 2008; 40(5):843-7.
Liao YC, Lo SH. PMID: 17521951; PMCID: PMC2323245.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions. J Biol Chem. 2007 Jun 15; 282(24):17806-15.
Eto M, Kirkbride J, Elliott E, Lo SH, Brautigan DL. PMID: 17435217.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Reverse interactomics: from peptides to proteins and to functions. ACS Chem Biol. 2007 Feb 20; 2(2):93-5.
Lo SH. PMID: 17313177.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1. J Cell Biol. 2007 Jan 01; 176(1):43-9.
Liao YC, Si L, deVere White RW, Lo SH. PMID: 17190795; PMCID: PMC2063623.
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PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
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Focal adhesions: what's new inside. Dev Biol. 2006 Jun 15; 294(2):280-91.
Lo SH. PMID: 16650401.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer. Cancer Res. 2006 Jan 01; 66(1):175-83.
You Z, Shi XB, DuRaine G, Haudenschild D, Tepper CG, Lo SH, Gandour-Edwards R, de Vere White RW, Reddi AH. PMID: 16397230.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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An efficient strategy to identify early TPA-responsive genes during differentiation of HL-60 cells. Gene Expr. 2006; 13(3):179-89.
Hu LY, Tepper CG, Lo SH, Lin WC. PMID: 17193924; PMCID: PMC6032445.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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The N-terminal half of talin2 is sufficient for mouse development and survival. Biochem Biophys Res Commun. 2005 Nov 18; 337(2):670-6.
Chen NT, Lo SH. PMID: 16202389.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Cleavage of cten by caspase-3 during apoptosis. Oncogene. 2005 Jun 16; 24(26):4311-4.
Lo SS, Lo SH, Lo SH. PMID: 15806167.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Inactivation of tensin3 in mice results in growth retardation and postnatal lethality. Dev Biol. 2005 Mar 15; 279(2):368-77.
Chiang MK, Liao YC, Kuwabara Y, Lo SH. PMID: 15733665.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3. Mol Cancer Res. 2004 Apr; 2(4):225-32.
Cui Y, Liao YC, Lo SH. PMID: 15140944.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Tensin. Int J Biochem Cell Biol. 2004 Jan; 36(1):31-4.
Lo SH. PMID: 14592531.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
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Regulation of tensin-promoted cell migration by its focal adhesion binding and Src homology domain 2. Biochem J. 2003 Mar 15; 370(Pt 3):1039-45.
Chen H, Lo SH. PMID: 12495434; PMCID: PMC1223245.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer. Cancer Res. 2002 Aug 01; 62(15):4217-21.
Lo SH, Lo TB. PMID: 12154022.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):733-8.
Chen H, Duncan IC, Bozorgchami H, Lo SH. PMID: 11792844; PMCID: PMC117374.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Regulation of articular chondrocyte phenotype by bone morphogenetic protein 7, interleukin 1, and cellular context is dependent on the cytoskeleton. Exp Cell Res. 2002 Jan 01; 272(1):32-44.
Vinall RL, Lo SH, Reddi AH. PMID: 11740863.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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A role of tensin in skeletal-muscle regeneration. Biochem J. 2001 Jun 15; 356(Pt 3):737-45.
Ishii A, Lo SH. PMID: 11389681; PMCID: PMC1221900.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Quantitative analysis of angiogenesis using confocal laser scanning microscopy. Angiogenesis. 2001; 4(3):187-91.
Guo L, Burke P, Lo SH, Gandour-Edwards R, Lau D. PMID: 11911016.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Molecular characterization of human tensin. Biochem J. 2000 Oct 15; 351 Pt 2:403-11.
Chen H, Ishii A, Wong WK, Chen LB, Lo SH. PMID: 11023826; PMCID: PMC1221376.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445. Cancer J Sci Am. 1999 Sep-Oct; 5(5):293-300.
Tikoo A, Cutler H, Lo SH, Chen LB, Maruta H. PMID: 10526670.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Inhibition of focal contact formation in cells transformed by p185neu. Mol Carcinog. 1999 Jun; 25(2):150-4.
Lo SS, Lo SH, Wang SC, Hung MC. PMID: 10365917.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Integrators of epidermal growth and differentiation: distinct functions for beta 1 and beta 4 integrins. Curr Opin Genet Dev. 1997 Oct; 7(5):672-82.
Fuchs E, Dowling J, Segre J, Lo SH, Yu QC. PMID: 9388785.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Progressive kidney degeneration in mice lacking tensin. J Cell Biol. 1997 Mar 24; 136(6):1349-61.
Lo SH, Yu QC, Degenstein L, Chen LB, Fuchs E. PMID: 9087448; PMCID: PMC2132507.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Platelet-derived growth factor-induced formation of tensin and phosphoinositide 3-kinase complexes. J Biol Chem. 1996 Sep 20; 271(38):23452-7.
Auger KR, Songyang Z, Lo SH, Roberts TM, Chen LB. PMID: 8798552.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. Oncogene. 1995 Sep 21; 11(6):1149-55.
Salgia R, Brunkhorst B, Pisick E, Li JL, Lo SH, Chen LB, Griffin JD. PMID: 7566975.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. J Biol Chem. 1995 Mar 10; 270(10):5039-47.
Salgia R, Li JL, Lo SH, Brunkhorst B, Kansas GS, Sobhany ES, Sun Y, Pisick E, Hallek M, Ernst T, et al. PMID: 7534286.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Tensin: a potential link between the cytoskeleton and signal transduction. Bioessays. 1994 Nov; 16(11):817-23.
Lo SH, Weisberg E, Chen LB. PMID: 7840759.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Molecular cloning of chick cardiac muscle tensin. Full-length cDNA sequence, expression, and characterization. J Biol Chem. 1994 Sep 02; 269(35):22310-9.
Lo SH, An Q, Bao S, Wong WK, Liu Y, Janmey PA, Hartwig JH, Chen LB. PMID: 8071358.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Interactions of tensin with actin and identification of its three distinct actin-binding domains. J Cell Biol. 1994 Jun; 125(5):1067-75.
Lo SH, Janmey PA, Hartwig JH, Chen LB. PMID: 8195290; PMCID: PMC2120063.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Focal adhesion as a signal transduction organelle. Cancer Metastasis Rev. 1994 Mar; 13(1):9-24.
Lo SH, Chen LB. PMID: 8143347.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Presence of an SH2 domain in the actin-binding protein tensin. Science. 1991 May 03; 252(5006):712-5.
Davis S, Lu ML, Lo SH, Lin S, Butler JA, Druker BJ, Roberts TM, An Q, Chen LB. PMID: 1708917.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells