Loading...

Su Hao Lo

Title(s)Professor, Biochemistry and Molecular Medicine
SchoolUniversity of California, Davis
Phone916-734-3656
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Wu ZY, Chiu CL, Lo E, Lee YJ, Yamada S, Lo SH. Hyperactivity of Mek in TNS1 knockouts leads to potential treatments for cystic kidney diseases. Cell Death Dis. 2019 Nov 18; 10(12):871. PMID: 31740667.
      View in: PubMed
    2. Cheah JS, Jacobs KA, Heinrich V, Lo SH, Yamada S. Force-induced recruitment of cten along keratin network in epithelial cells. Proc Natl Acad Sci U S A. 2019 Sep 16. PMID: 31527270.
      View in: PubMed
    3. Hong SY, Shih YP, Lo A, Lo SH. Identification of subcellular targeting sequences of Cten reveals its role in cell proliferation. Biochim Biophys Acta Mol Cell Res. 2019 03; 1866(3):450-458. PMID: 30321615.
      View in: PubMed
    4. Shih YP, Sun P, Wang A, Lo SH. Corrigendum to "Tensin1 positively regulates RhoA activity through its interaction with DLC1" [Biochimica et Biophysica Acta 1853/12 (2015) 3258-3265]. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1383. PMID: 29866430.
      View in: PubMed
    5. Lo SH. Tensins. Curr Biol. 2017 May 08; 27(9):R331-R332. PMID: 28486112.
      View in: PubMed
    6. Shih YP, Yuan SY, Lo SH. Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process. Cancer Lett. 2017 07 10; 398:46-51. PMID: 28408355.
      View in: PubMed
    7. Hong SY, Shih YP, Sun P, Hsieh WJ, Lin WC, Lo SH. Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers. Oncotarget. 2016 Jun 21; 7(25):38143-38153. PMID: 27203214.
      View in: PubMed
    8. Yang K, Wu WM, Chen YC, Lo SH, Liao YC. ?Np63a Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion. PLoS One. 2016; 11(1):e0147542. PMID: 26784942.
      View in: PubMed
    9. Shih YP, Sun P, Wang A, Lo SH. Tensin1 positively regulates RhoA activity through its interaction with DLC1. Biochim Biophys Acta. 2015 Dec; 1853(12):3258-65. PMID: 26427649.
      View in: PubMed
    10. Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, Jeunemaitre X. Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nat Genet. 2015 Oct; 47(10):1206-11. PMID: 26301497.
      View in: PubMed
    11. Lo SH. C-terminal tensin-like (CTEN): a promising biomarker and target for cancer. Int J Biochem Cell Biol. 2014 Jun; 51:150-4. PMID: 24735711.
      View in: PubMed
    12. Hong SY, Shih YP, Li T, Carraway KL, Lo SH. CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation. Cancer Res. 2013 Aug 15; 73(16):5266-76. PMID: 23774213.
      View in: PubMed
    13. Fujita M, Ieguchi K, Cedano-Prieto DM, Fong A, Wilkerson C, Chen JQ, Wu M, Lo SH, Cheung AT, Wilson MD, Cardiff RD, Borowsky AD, Takada YK, Takada Y. An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R. J Biol Chem. 2013 Jul 05; 288(27):19593-603. PMID: 23696648.
      View in: PubMed
    14. Hung SY, Shih YP, Chen M, Lo SH. Up-regulated cten by FGF2 contributes to FGF2-mediated cell migration. Mol Carcinog. 2014 Oct; 53(10):787-92. PMID: 23625726.
      View in: PubMed
    15. Chen NT, Kuwabara Y, Conley C, Liao YC, Hong SY, Chen M, Shih YP, Chen HW, Hsieh F, Lo SH. Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene. Gene. 2013 May 15; 520(2):90-7. PMID: 23500447.
      View in: PubMed
    16. Li JR, Shi L, Deng Z, Lo SH, Liu GY. Nanostructures of designed geometry and functionality enable regulation of cellular signaling processes. Biochemistry. 2012 Jul 31; 51(30):5876-93. PMID: 22783801.
      View in: PubMed
    17. Shih YP, Takada Y, Lo SH. Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells. Mol Cancer Res. 2012 Jan; 10(1):34-9. PMID: 22064653.
      View in: PubMed
    18. Albasri A, Al-Ghamdi S, Fadhil W, Aleskandarany M, Liao YC, Jackson D, Lobo DN, Lo SH, Kumari R, Durrant L, Watson S, Kindle KB, Ilyas M. Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer. Oncogene. 2011 Jun 30; 30(26):2997-3002. PMID: 21339732.
      View in: PubMed
    19. Shih YP, Liao YC, Lin Y, Lo SH. DLC1 negatively regulates angiogenesis in a paracrine fashion. Cancer Res. 2010 Nov 01; 70(21):8270-5. PMID: 20861185.
      View in: PubMed
    20. Lin Y, Chen NT, Shih YP, Liao YC, Xue L, Lo SH. DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. Oncogene. 2010 May 20; 29(20):3010-6. PMID: 20208559.
      View in: PubMed
    21. Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, Chen NT, Ma AH, Desai SJ, Lo SH, Evans CP, Lam KS, Kung HJ. Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer. 2010 Jan; 1(1):40-9. PMID: 20811583.
      View in: PubMed
    22. Hsieh SC, Chen NT, Lo SH. Conditional loss of PTEN leads to skeletal abnormalities and lipoma formation. Mol Carcinog. 2009 Jun; 48(6):545-52. PMID: 18973188.
      View in: PubMed
    23. Liao YC, Chen NT, Shih YP, Dong Y, Lo SH. Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin. Cancer Res. 2009 Jun 01; 69(11):4563-6. PMID: 19487278.
      View in: PubMed
    24. Lulevich V, Shih YP, Lo SH, Liu GY. Cell tracing dyes significantly change single cell mechanics. J Phys Chem B. 2009 May 07; 113(18):6511-9. PMID: 19366241.
      View in: PubMed
    25. Liao YC, Shih YP, Lo SH. Mutations in the focal adhesion targeting region of deleted in liver cancer-1 attenuate their expression and function. Cancer Res. 2008 Oct 01; 68(19):7718-22. PMID: 18829524.
      View in: PubMed
    26. Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Nat Cell Biol. 2007 Aug; 9(8):961-9. PMID: 17643115.
      View in: PubMed
    27. Liao YC, Lo SH. Deleted in liver cancer-1 (DLC-1): a tumor suppressor not just for liver. Int J Biochem Cell Biol. 2008; 40(5):843-7. PMID: 17521951.
      View in: PubMed
    28. Eto M, Kirkbride J, Elliott E, Lo SH, Brautigan DL. Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions. J Biol Chem. 2007 Jun 15; 282(24):17806-15. PMID: 17435217.
      View in: PubMed
    29. Lo SH. Reverse interactomics: from peptides to proteins and to functions. ACS Chem Biol. 2007 Feb 20; 2(2):93-5. PMID: 17313177.
      View in: PubMed
    30. Liao YC, Si L, deVere White RW, Lo SH. The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1. J Cell Biol. 2007 Jan 01; 176(1):43-9. PMID: 17190795.
      View in: PubMed
    31. Lo SH. Focal adhesions: what's new inside. Dev Biol. 2006 Jun 15; 294(2):280-91. PMID: 16650401.
      View in: PubMed
    32. You Z, Shi XB, DuRaine G, Haudenschild D, Tepper CG, Lo SH, Gandour-Edwards R, de Vere White RW, Reddi AH. Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer. Cancer Res. 2006 Jan 01; 66(1):175-83. PMID: 16397230.
      View in: PubMed
    33. Hu LY, Tepper CG, Lo SH, Lin WC. An efficient strategy to identify early TPA-responsive genes during differentiation of HL-60 cells. Gene Expr. 2006; 13(3):179-89. PMID: 17193924.
      View in: PubMed
    34. Chen NT, Lo SH. The N-terminal half of talin2 is sufficient for mouse development and survival. Biochem Biophys Res Commun. 2005 Nov 18; 337(2):670-6. PMID: 16202389.
      View in: PubMed
    35. Lo SS, Lo SH, Lo SH. Cleavage of cten by caspase-3 during apoptosis. Oncogene. 2005 Jun 16; 24(26):4311-4. PMID: 15806167.
      View in: PubMed
    36. Chiang MK, Liao YC, Kuwabara Y, Lo SH. Inactivation of tensin3 in mice results in growth retardation and postnatal lethality. Dev Biol. 2005 Mar 15; 279(2):368-77. PMID: 15733665.
      View in: PubMed
    37. Cui Y, Liao YC, Lo SH. Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3. Mol Cancer Res. 2004 Apr; 2(4):225-32. PMID: 15140944.
      View in: PubMed
    38. Lo SH. Tensin. Int J Biochem Cell Biol. 2004 Jan; 36(1):31-4. PMID: 14592531.
      View in: PubMed
    39. Chen H, Lo SH. Regulation of tensin-promoted cell migration by its focal adhesion binding and Src homology domain 2. Biochem J. 2003 Mar 15; 370(Pt 3):1039-45. PMID: 12495434.
      View in: PubMed
    40. Lo SH, Lo TB. Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer. Cancer Res. 2002 Aug 01; 62(15):4217-21. PMID: 12154022.
      View in: PubMed
    41. Chen H, Duncan IC, Bozorgchami H, Lo SH. Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):733-8. PMID: 11792844.
      View in: PubMed
    42. Vinall RL, Lo SH, Reddi AH. Regulation of articular chondrocyte phenotype by bone morphogenetic protein 7, interleukin 1, and cellular context is dependent on the cytoskeleton. Exp Cell Res. 2002 Jan 01; 272(1):32-44. PMID: 11740863.
      View in: PubMed
    43. Ishii A, Lo SH. A role of tensin in skeletal-muscle regeneration. Biochem J. 2001 Jun 15; 356(Pt 3):737-45. PMID: 11389681.
      View in: PubMed
    44. Guo L, Burke P, Lo SH, Gandour-Edwards R, Lau D. Quantitative analysis of angiogenesis using confocal laser scanning microscopy. Angiogenesis. 2001; 4(3):187-91. PMID: 11911016.
      View in: PubMed
    45. Chen H, Ishii A, Wong WK, Chen LB, Lo SH. Molecular characterization of human tensin. Biochem J. 2000 Oct 15; 351 Pt 2:403-11. PMID: 11023826.
      View in: PubMed
    46. Tikoo A, Cutler H, Lo SH, Chen LB, Maruta H. Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445. Cancer J Sci Am. 1999 Sep-Oct; 5(5):293-300. PMID: 10526670.
      View in: PubMed
    47. Lo SS, Lo SH, Wang SC, Hung MC. Inhibition of focal contact formation in cells transformed by p185neu. Mol Carcinog. 1999 Jun; 25(2):150-4. PMID: 10365917.
      View in: PubMed
    48. Fuchs E, Dowling J, Segre J, Lo SH, Yu QC. Integrators of epidermal growth and differentiation: distinct functions for beta 1 and beta 4 integrins. Curr Opin Genet Dev. 1997 Oct; 7(5):672-82. PMID: 9388785.
      View in: PubMed
    49. Lo SH, Yu QC, Degenstein L, Chen LB, Fuchs E. Progressive kidney degeneration in mice lacking tensin. J Cell Biol. 1997 Mar 24; 136(6):1349-61. PMID: 9087448.
      View in: PubMed
    50. Auger KR, Songyang Z, Lo SH, Roberts TM, Chen LB. Platelet-derived growth factor-induced formation of tensin and phosphoinositide 3-kinase complexes. J Biol Chem. 1996 Sep 20; 271(38):23452-7. PMID: 8798552.
      View in: PubMed
    51. Salgia R, Brunkhorst B, Pisick E, Li JL, Lo SH, Chen LB, Griffin JD. Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. Oncogene. 1995 Sep 21; 11(6):1149-55. PMID: 7566975.
      View in: PubMed
    52. Salgia R, Li JL, Lo SH, Brunkhorst B, Kansas GS, Sobhany ES, Sun Y, Pisick E, Hallek M, Ernst T. Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. J Biol Chem. 1995 Mar 10; 270(10):5039-47. PMID: 7534286.
      View in: PubMed
    53. Lo SH, Weisberg E, Chen LB. Tensin: a potential link between the cytoskeleton and signal transduction. Bioessays. 1994 Nov; 16(11):817-23. PMID: 7840759.
      View in: PubMed
    54. Lo SH, An Q, Bao S, Wong WK, Liu Y, Janmey PA, Hartwig JH, Chen LB. Molecular cloning of chick cardiac muscle tensin. Full-length cDNA sequence, expression, and characterization. J Biol Chem. 1994 Sep 02; 269(35):22310-9. PMID: 8071358.
      View in: PubMed
    55. Lo SH, Janmey PA, Hartwig JH, Chen LB. Interactions of tensin with actin and identification of its three distinct actin-binding domains. J Cell Biol. 1994 Jun; 125(5):1067-75. PMID: 8195290.
      View in: PubMed
    56. Lo SH, Chen LB. Focal adhesion as a signal transduction organelle. Cancer Metastasis Rev. 1994 Mar; 13(1):9-24. PMID: 8143347.
      View in: PubMed
    57. Davis S, Lu ML, Lo SH, Lin S, Butler JA, Druker BJ, Roberts TM, An Q, Chen LB. Presence of an SH2 domain in the actin-binding protein tensin. Science. 1991 May 03; 252(5006):712-5. PMID: 1708917.
      View in: PubMed