Julie Bossuyt

vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Hegyi B, Bers DM, Bossuyt J. CaMKII signaling in heart diseases: Emerging role in diabetic cardiomyopathy. J Mol Cell Cardiol. 2019 Jan 08; 127:246-259. PMID: 30633874.
      View in: PubMed
    2. Wood BM, Simon M, Galice S, Alim CC, Ferrero M, Pinna NN, Bers DM, Bossuyt J. Cardiac CaMKII activation promotes rapid translocation to its extra-dyadic targets. J Mol Cell Cardiol. 2018 Dec; 125:18-28. PMID: 30321537.
      View in: PubMed
    3. Hegyi B, Bossuyt J, Griffiths LG, Shimkunas R, Coulibaly Z, Jian Z, Grimsrud KN, Sondergaard CS, Ginsburg KS, Chiamvimonvat N, Belardinelli L, Varró A, Papp JG, Pollesello P, Levijoki J, Izu LT, Boyd WD, Bányász T, Bers DM, Chen-Izu Y. Complex electrophysiological remodeling in postinfarction ischemic heart failure. Proc Natl Acad Sci U S A. 2018 03 27; 115(13):E3036-E3044. PMID: 29531045.
      View in: PubMed
    4. Hegyi B, Bossuyt J, Ginsburg KS, Mendoza LM, Talken L, Ferrier WT, Pogwizd SM, Izu LT, Chen-Izu Y, Bers DM. Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and ß-Adrenergic Effects on Delayed- and Inward-Rectifier Potassium Currents. Circ Arrhythm Electrophysiol. 2018 Feb; 11(2):e005852. PMID: 29437761.
      View in: PubMed
    5. Wood BM, Bossuyt J. Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System. Front Pharmacol. 2017; 8:9. PMID: 28174535.
      View in: PubMed
    6. Himes RD, Smolin N, Kukol A, Bossuyt J, Bers DM, Robia SL. L30A Mutation of Phospholemman Mimics Effects of Cardiac Glycosides in Isolated Cardiomyocytes. Biochemistry. 2016 Nov 08; 55(44):6196-6204. PMID: 27718550.
      View in: PubMed
    7. Barbagallo F, Xu B, Reddy GR, West T, Wang Q, Fu Q, Li M, Shi Q, Ginsburg KS, Ferrier W, Isidori AM, Naro F, Patel HH, Bossuyt J, Bers D, Xiang YK. Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure. Circ Res. 2016 Sep 30; 119(8):931-43. PMID: 27576469.
      View in: PubMed
    8. Erickson JR, Nichols CB, Uchinoumi H, Stein ML, Bossuyt J, Bers DM. S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II d. J Biol Chem. 2015 Oct 16; 290(42):25646-56. PMID: 26316536; PMCID: PMC4646208 [Available on 10/16/16].
    9. Pereira L, Rehmann H, Lao DH, Erickson JR, Bossuyt J, Chen J, Bers DM. Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes. Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13):3991-6. PMID: 25829540; PMCID: PMC4386405.
    10. Shattock MJ, Ottolia M, Bers DM, Blaustein MP, Boguslavskyi A, Bossuyt J, Bridge JH, Chen-Izu Y, Clancy CE, Edwards A, Goldhaber J, Kaplan J, Lingrel JB, Pavlovic D, Philipson K, Sipido KR, Xie ZJ. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart. J Physiol. 2015 Mar 15; 593(6):1361-82. PMID: 25772291; PMCID: PMC4376416.
    11. Bossuyt J, Bers DM. Assessing GPCR and G protein signaling to the nucleus in live cells using fluorescent biosensors. Methods Mol Biol. 2015; 1234:149-59. PMID: 25304355.
      View in: PubMed
    12. Bossuyt J. Nuclear remodelling: a consequence of nucleocytoplasmic traffic run amok? Cardiovasc Res. 2015 Jan 01; 105(1):6-7. PMID: 25504625.
      View in: PubMed
    13. Ljubojevic S, Radulovic S, Leitinger G, Sedej S, Sacherer M, Holzer M, Winkler C, Pritz E, Mittler T, Schmidt A, Sereinigg M, Wakula P, Zissimopoulos S, Bisping E, Post H, Marsche G, Bossuyt J, Bers DM, Kockskämper J, Pieske B. Early remodeling of perinuclear Ca2+ stores and nucleoplasmic Ca2+ signaling during the development of hypertrophy and heart failure. Circulation. 2014 Jul 15; 130(3):244-55. PMID: 24928680; PMCID: PMC4101040.
    14. Despa S, Shui B, Bossuyt J, Lang D, Kotlikoff MI, Bers DM. Junctional cleft [Ca²?]i measurements using novel cleft-targeted Ca²? sensors. Circ Res. 2014 Jul 18; 115(3):339-47. PMID: 24871564; PMCID: PMC4132890.
    15. Nichols CB, Chang CW, Ferrero M, Wood BM, Stein ML, Ferguson AJ, Ha D, Rigor RR, Bossuyt S, Bossuyt J. ß-adrenergic signaling inhibits Gq-dependent protein kinase D activation by preventing protein kinase D translocation. Circ Res. 2014 Apr 25; 114(9):1398-409. PMID: 24643961; PMCID: PMC4031034.
    16. Bossuyt J, Bers DM. Visualizing CaMKII and CaM activity: a paradigm of compartmentalized signaling. J Mol Med (Berl). 2013 Aug; 91(8):907-16. PMID: 23775230; PMCID: PMC3962229.
    17. Gold JI, Martini JS, Hullmann J, Gao E, Chuprun JK, Lee L, Tilley DG, Rabinowitz JE, Bossuyt J, Bers DM, Koch WJ. Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process. PLoS One. 2013; 8(3):e57324. PMID: 23472081; PMCID: PMC3589474.
    18. Lu X, Ginsburg KS, Kettlewell S, Bossuyt J, Smith GL, Bers DM. Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release. Circ Res. 2013 Feb 01; 112(3):424-31. PMID: 23243207; PMCID: PMC3566246.
    19. Khafaga M, Bossuyt J, Mamikonian L, Li JC, Lee LL, Yarov-Yarovoy V, Despa S, Bers DM. Na?/K?-ATPase E960 and phospholemman F28 are critical for their functional interaction. Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50):20756-61. PMID: 23185013; PMCID: PMC3528502.
    20. Chang CW, Lee L, Yu D, Dao K, Bossuyt J, Bers DM. Acute ß-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activation. J Biol Chem. 2013 Jan 04; 288(1):192-204. PMID: 23161540; PMCID: PMC3537013.
    21. Haghighi K, Pritchard T, Bossuyt J, Waggoner JR, Yuan Q, Fan GC, Osinska H, Anjak A, Rubinstein J, Robbins J, Bers DM, Kranias EG. The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. J Mol Cell Cardiol. 2012 Mar; 52(3):773-82. PMID: 22155237; PMCID: PMC3376549.
    22. Erickson JR, Patel R, Ferguson A, Bossuyt J, Bers DM. Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes. Circ Res. 2011 Sep 16; 109(7):729-38. PMID: 21835909; PMCID: PMC3182829.
    23. Bossuyt J, Chang CW, Helmstadter K, Kunkel MT, Newton AC, Campbell KS, Martin JL, Bossuyt S, Robia SL, Bers DM. Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin. J Biol Chem. 2011 Sep 23; 286(38):33390-400. PMID: 21795686; PMCID: PMC3190922.
    24. Song Q, Pallikkuth S, Bossuyt J, Bers DM, Robia SL. Phosphomimetic mutations enhance oligomerization of phospholemman and modulate its interaction with the Na/K-ATPase. J Biol Chem. 2011 Mar 18; 286(11):9120-6. PMID: 21220422; PMCID: PMC3059012.
    25. Han F, Bossuyt J, Martin JL, Despa S, Bers DM. Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPase. Am J Physiol Cell Physiol. 2010 Dec; 299(6):C1363-9. PMID: 20861470; PMCID: PMC3006338.
    26. Bossuyt J, Despa S, Han F, Hou Z, Robia SL, Lingrel JB, Bers DM. Isoform specificity of the Na/K-ATPase association and regulation by phospholemman. J Biol Chem. 2009 Sep 25; 284(39):26749-57. PMID: 19638348; PMCID: PMC2785363.
    27. Song Q, Saucerman JJ, Bossuyt J, Bers DM. Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets. J Biol Chem. 2008 Nov 14; 283(46):31531-40. PMID: 18790737; PMCID: PMC2581591.
    28. Kelly EM, Hou Z, Bossuyt J, Bers DM, Robia SL. Phospholamban oligomerization, quaternary structure, and sarco(endo)plasmic reticulum calcium ATPase binding measured by fluorescence resonance energy transfer in living cells. J Biol Chem. 2008 May 02; 283(18):12202-11. PMID: 18287099; PMCID: PMC2335368.
    29. Bossuyt J, Helmstadter K, Wu X, Clements-Jewery H, Haworth RS, Avkiran M, Martin JL, Pogwizd SM, Bers DM. Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure. Circ Res. 2008 Mar 28; 102(6):695-702. PMID: 18218981.
      View in: PubMed
    30. Han F, Bossuyt J, Despa S, Tucker AL, Bers DM. Phospholemman phosphorylation mediates the protein kinase C-dependent effects on Na+/K+ pump function in cardiac myocytes. Circ Res. 2006 Dec 08; 99(12):1376-83. PMID: 17095720.
      View in: PubMed
    31. Bers DM, Despa S, Bossuyt J. Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes. Ann N Y Acad Sci. 2006 Oct; 1080:165-77. PMID: 17132783.
      View in: PubMed
    32. Maier LS, Ziolo MT, Bossuyt J, Persechini A, Mestril R, Bers DM. Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. J Mol Cell Cardiol. 2006 Sep; 41(3):451-8. PMID: 16765983.
      View in: PubMed
    33. Bossuyt J, Despa S, Martin JL, Bers DM. Phospholemman phosphorylation alters its fluorescence resonance energy transfer with the Na/K-ATPase pump. J Biol Chem. 2006 Oct 27; 281(43):32765-73. PMID: 16943195.
      View in: PubMed
    34. Wu X, Zhang T, Bossuyt J, Li X, McKinsey TA, Dedman JR, Olson EN, Chen J, Brown JH, Bers DM. Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest. 2006 Mar; 116(3):675-82. PMID: 16511602; PMCID: PMC1386110.
    35. Remus TP, Zima AV, Bossuyt J, Bare DJ, Martin JL, Blatter LA, Bers DM, Mignery GA. Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution. J Biol Chem. 2006 Jan 06; 281(1):608-16. PMID: 16249182.
      View in: PubMed
    36. Bossuyt J, Ai X, Moorman JR, Pogwizd SM, Bers DM. Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure. Circ Res. 2005 Sep 16; 97(6):558-65. PMID: 16100047.
      View in: PubMed
    37. Despa S, Bossuyt J, Han F, Ginsburg KS, Jia LG, Kutchai H, Tucker AL, Bers DM. Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes. Circ Res. 2005 Aug 05; 97(3):252-9. PMID: 16002746.
      View in: PubMed
    38. Ziolo MT, Martin JL, Bossuyt J, Bers DM, Pogwizd SM. Adenoviral gene transfer of mutant phospholamban rescues contractile dysfunction in failing rabbit myocytes with relatively preserved SERCA function. Circ Res. 2005 Apr 29; 96(8):815-7. PMID: 15790952.
      View in: PubMed
    39. Ziolo MT, Maier LS, Piacentino V, Bossuyt J, Houser SR, Bers DM. Myocyte nitric oxide synthase 2 contributes to blunted beta-adrenergic response in failing human hearts by decreasing Ca2+ transients. Circulation. 2004 Apr 20; 109(15):1886-91. PMID: 15037528.
      View in: PubMed