Manuel F Navedo

Title(s)Professor, Pharmacology
SchoolSchool of Medicine
AddressOne Shields Avenue MED: PHARM Tupper 2420
CA 95616
Phone530-752-6880
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    Collapse Research 
    Collapse Research Activities and Funding
    Coupling of Vascular Cav1.2 Channels In Health & Disease
    NIH/NHLBI R01HL121059Jul 1, 2015 - Apr 30, 2019
    Role: Principal Investigator
    Calcium Sparklers-Induced Vascular Dysfunction During Diabetes
    NIH/NHLBI R01HL098200Jul 19, 2010 - May 31, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Deciphering cellular signals in adult mouse sinoatrial node cells. iScience. 2022 Jan 21; 25(1):103693. Reddy GR, Ren L, Thai PN, Caldwell JL, Zaccolo M, Bossuyt J, Ripplinger CM, Xiang YK, Nieves-Cintrón M, Chiamvimonvat N, Navedo MF. PMID: 35036877; PMCID: PMC8749457.
      View in: PubMed   Mentions:
    2. Mechanisms and physiological implications of cooperative gating of clustered ion channels. Physiol Rev. 2022 07 01; 102(3):1159-1210. Dixon RE, Navedo MF, Binder MD, Santana LF. PMID: 34927454; PMCID: PMC8934683.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    3. Genetically engineered mice for combinatorial cardiovascular optobiology. Elife. 2021 10 29; 10. Lee FK, Lee JC, Shui B, Reining S, Jibilian M, Small DM, Jones JS, Allan-Rahill NH, Lamont MR, Rizzo MA, Tajada S, Navedo MF, Santana LF, Nishimura N, Kotlikoff MI. PMID: 34711305; PMCID: PMC8555989.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. β-Adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins. Proc Natl Acad Sci U S A. 2021 02 16; 118(7). Del Villar SG, Voelker TL, Westhoff M, Reddy GR, Spooner HC, Navedo MF, Dickson EJ, Dixon RE. PMID: 33558236; PMCID: PMC7896340.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways. Basic Res Cardiol. 2020 11 25; 115(6):71. Hegyi B, Borst JM, Bailey LRJ, Shen EY, Lucena AJ, Navedo MF, Bossuyt J, Bers DM. PMID: 33237428; PMCID: PMC8349245.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    6. AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2. Nat Commun. 2020 10 20; 11(1):5303. Prada MP, Syed AU, Reddy GR, Martín-Aragón Baudel M, Flores-Tamez VA, Sasse KC, Ward SM, Sirish P, Chiamvimonvat N, Bartels P, Dickson EJ, Hell JW, Scott JD, Santana LF, Xiang YK, Navedo MF, Nieves-Cintrón M. PMID: 33082339; PMCID: PMC7575592.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. α-Actinin-1 promotes activity of the L-type Ca2+ channel Cav1.2. EMBO J. 2020 Sep 15; 39(18):e106171. Turner M, Anderson DE, Bartels P, Nieves-Cintron M, Coleman AM, Henderson PB, Man KNM, Tseng PY, Yarov-Yarovoy V, Bers DM, Navedo MF, Horne MC, Ames JB, Hell JW. PMID: 33433005; PMCID: PMC7507692.
      View in: PubMed   Mentions:    Fields:    
    8. Maladaptive response of arterial myocytes to chronic exposure to Ca2+ channel blockers. Proc Natl Acad Sci U S A. 2020 08 04; 117(31):18151-18153. O'Dwyer SC, Navedo MF, Santana LF. PMID: 32680960; PMCID: PMC7414083.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Cellular and molecular effects of hyperglycemia on ion channels in vascular smooth muscle. Cell Mol Life Sci. 2021 Jan; 78(1):31-61. Nieves-Cintrón M, Flores-Tamez VA, Le T, Baudel MM, Navedo MF. PMID: 32594191; PMCID: PMC7765743.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    10. TRPML1ng on sparks. Sci Signal. 2020 06 23; 13(637). Nieves-Cintron M, Santana LF, Navedo MF. PMID: 32576679; PMCID: PMC7384335.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    11. Purinergic Signaling During Hyperglycemia in Vascular Smooth Muscle Cells. Front Endocrinol (Lausanne). 2020; 11:329. Martin-Aragon Baudel M, Espinosa-Tanguma R, Nieves-Cintron M, Navedo MF. PMID: 32528416; PMCID: PMC7256624.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    12. α-Actinin-1 promotes activity of the L-type Ca2+ channel Cav 1.2. EMBO J. 2020 03 02; 39(5):e102622. Turner M, Anderson DE, Bartels P, Nieves-Cintron M, Coleman AM, Henderson PB, Man KNM, Tseng PY, Yarov-Yarovoy V, Bers DM, Navedo MF, Horne MC, Ames JB, Hell JW. PMID: 31985069; PMCID: PMC7049811.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons. Elife. 2019 10 14; 8. Shen A, Chen D, Kaur M, Bartels P, Xu B, Shi Q, Martinez JM, Man KM, Nieves-Cintron M, Hell JW, Navedo MF, Yu XY, Xiang YK. PMID: 31609201; PMCID: PMC6813027.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. β2 Adrenergic Receptor Complexes with the L-Type Ca2+ Channel CaV1.2 and AMPA-Type Glutamate Receptors: Paradigms for Pharmacological Targeting of Protein Interactions. Annu Rev Pharmacol Toxicol. 2020 01 06; 60:155-174. Man KNM, Navedo MF, Horne MC, Hell JW. PMID: 31561738; PMCID: PMC7029424.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    15. A stochastic model of ion channel cluster formation in the plasma membrane. J Gen Physiol. 2019 09 02; 151(9):1116-1134. Sato D, Hernández-Hernández G, Matsumoto C, Tajada S, Moreno CM, Dixon RE, O'Dwyer S, Navedo MF, Trimmer JS, Clancy CE, Binder MD, Santana LF. PMID: 31371391; PMCID: PMC6719406.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    16. Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia. J Clin Invest. 2019 06 04; 129(8):3140-3152. Syed AU, Reddy GR, Ghosh D, Prada MP, Nystoriak MA, Morotti S, Grandi E, Sirish P, Chiamvimonvat N, Hell JW, Santana LF, Xiang YK, Nieves-Cintrón M, Navedo MF. PMID: 31162142; PMCID: PMC6668679.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    17. β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes. J Physiol. 2019 04; 597(8):2139-2162. Ito DW, Hannigan KI, Ghosh D, Xu B, Del Villar SG, Xiang YK, Dickson EJ, Navedo MF, Dixon RE. PMID: 30714156; PMCID: PMC6462464.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    18. A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia. Elife. 2019 03 01; 8. Prada MP, Syed AU, Buonarati OR, Reddy GR, Nystoriak MA, Ghosh D, Simó S, Sato D, Sasse KC, Ward SM, Santana LF, Xiang YK, Hell JW, Nieves-Cintrón M, Navedo MF. PMID: 30821687; PMCID: PMC6397001.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    19. Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. Proc Natl Acad Sci U S A. 2018 12 04; 115(49):E11465-E11474. Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD. PMID: 30455320; PMCID: PMC6298107.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    20. Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. Biochim Biophys Acta Mol Cell Res. 2018 09; 1865(9):1341-1355. Ghosh D, Nieves-Cintrón M, Tajada S, Brust-Mascher I, Horne MC, Hell JW, Dixon RE, Santana LF, Navedo MF. PMID: 29959960; PMCID: PMC6407617.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    21. Corrigendum: Diabetic cornea wounds produce significantly weaker electric signals that may contribute to impaired healing. Sci Rep. 2018 Jun 27; 8:46997. Shen Y, Pfluger T, Ferreira F, Liang J, Navedo MF, Zeng Q, Reid B, Zhao M. PMID: 29947346; PMCID: PMC6020011.
      View in: PubMed   Mentions:    Fields:    
    22. Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell. Nat Commun. 2018 03 13; 9(1):1050. Shen A, Nieves-Cintron M, Deng Y, Shi Q, Chowdhury D, Qi J, Hell JW, Navedo MF, Xiang YK. PMID: 29535304; PMCID: PMC5849717.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    23. Going with the flow: contextual fine-tuning of vascular reactivity. J Physiol. 2018 04 01; 596(7):1127-1128. Navedo MF, Amberg GC. PMID: 29427447; PMCID: PMC5878216.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    24. A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics. PLoS Comput Biol. 2018 01; 14(1):e1005906. Sato D, Dixon RE, Santana LF, Navedo MF. PMID: 29338006; PMCID: PMC5786340.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    25. Coronary microvascular Kv1 channels as regulatory sensors of intracellular pyridine nucleotide redox potential. Microcirculation. 2018 01; 25(1). Dwenger MM, Ohanyan V, Navedo MF, Nystoriak MA. PMID: 29110409; PMCID: PMC5760281.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    26. Regulation of microvascular function by voltage-gated potassium channels: New tricks for an "ancient" dog. Microcirculation. 2018 01; 25(1). Nystoriak MA, Navedo MF. PMID: 29239491; PMCID: PMC5826567.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    27. Regulation of voltage-gated potassium channels in vascular smooth muscle during hypertension and metabolic disorders. Microcirculation. 2018 01; 25(1). Nieves-Cintrón M, Syed AU, Nystoriak MA, Navedo MF. PMID: 29044853; PMCID: PMC5760350.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    28. Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes. Sci Rep. 2017 10 25; 7(1):14058. Nieves-Cintrón M, Syed AU, Buonarati OR, Rigor RR, Nystoriak MA, Ghosh D, Sasse KC, Ward SM, Santana LF, Hell JW, Navedo MF. PMID: 29070899; PMCID: PMC5656614.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    29. Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes. J Gen Physiol. 2017 Jun 05; 149(6):639-659. Tajada S, Moreno CM, O'Dwyer S, Woods S, Sato D, Navedo MF, Santana LF. PMID: 28507079; PMCID: PMC5460949.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    30. Predominant contribution of L-type Cav1.2 channel stimulation to impaired intracellular calcium and cerebral artery vasoconstriction in diabetic hyperglycemia. Channels (Austin). 2017 Jul 04; 11(4):340-346. Morotti S, Nieves-Cintrón M, Nystoriak MA, Navedo MF, Grandi E. PMID: 28631947; PMCID: PMC5555263.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    31. Science Signaling Podcast for 24 January 2017: Tissue-specific regulation of L-type calcium channels. Sci Signal. 2017 01 24; 10(463). Hell JW, Navedo MF, VanHook AM. PMID: 28119457; PMCID: PMC5312676.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    32. Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons. Sci Signal. 2017 01 24; 10(463). Qian H, Patriarchi T, Price JL, Matt L, Lee B, Nieves-Cintrón M, Buonarati OR, Chowdhury D, Nanou E, Nystoriak MA, Catterall WA, Poomvanicha M, Hofmann F, Navedo MF, Hell JW. PMID: 28119465; PMCID: PMC5310946.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    33. Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes. Sci Signal. 2017 01 24; 10(463). Nystoriak MA, Nieves-Cintrón M, Patriarchi T, Buonarati OR, Prada MP, Morotti S, Grandi E, Fernandes JD, Forbush K, Hofmann F, Sasse KC, Scott JD, Ward SM, Hell JW, Navedo MF. PMID: 28119464; PMCID: PMC5297430.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    34. Potassium channels in the heart: structure, function and regulation. J Physiol. 2017 04 01; 595(7):2209-2228. Grandi E, Sanguinetti MC, Bartos DC, Bers DM, Chen-Izu Y, Chiamvimonvat N, Colecraft HM, Delisle BP, Heijman J, Navedo MF, Noskov S, Proenza C, Vandenberg JI, Yarov-Yarovoy V. PMID: 27861921; PMCID: PMC5374109.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    35. Calcium Channels in Vascular Smooth Muscle. Adv Pharmacol. 2017; 78:49-87. Ghosh D, Syed AU, Prada MP, Nystoriak MA, Santana LF, Nieves-Cintrón M, Navedo MF. PMID: 28212803; PMCID: PMC5439506.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    36. Diabetic cornea wounds produce significantly weaker electric signals that may contribute to impaired healing. Sci Rep. 2016 06 10; 6:26525. Shen Y, Pfluger T, Ferreira F, Liang J, Navedo MF, Zeng Q, Reid B, Zhao M. PMID: 27283241; PMCID: PMC4901296.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    37. Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor. EMBO J. 2016 06 15; 35(12):1330-45. Patriarchi T, Qian H, Di Biase V, Malik ZA, Chowdhury D, Price JL, Hammes EA, Buonarati OR, Westenbroek RE, Catterall WA, Hofmann F, Xiang YK, Murphy GG, Chen CY, Navedo MF, Hell JW. PMID: 27103070; PMCID: PMC4910527.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    38. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes. J Biol Chem. 2016 Mar 04; 291(10):4912. Nieves-Cintrón M, Nystoriak MA, Prada MP, Johnson K, Fayer W, Dell'Acqua ML, Scott JD, Navedo MF. PMID: 26945093; PMCID: PMC4777829.
      View in: PubMed   Mentions: 1     Fields:    
    39. AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction. Cell Signal. 2016 07; 28(7):733-40. Nieves-Cintrón M, Hirenallur-Shanthappa D, Nygren PJ, Hinke SA, Dell'Acqua ML, Langeberg LK, Navedo M, Santana LF, Scott JD. PMID: 26724383; PMCID: PMC4902329.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    40. Arterial Smooth Muscle Mitochondria Amplify Hydrogen Peroxide Microdomains Functionally Coupled to L-Type Calcium Channels. Circ Res. 2015 Dec 04; 117(12):1013-23. Chaplin NL, Nieves-Cintrón M, Fresquez AM, Navedo MF, Amberg GC. PMID: 26390880; PMCID: PMC4670591.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    41. Graded Ca²⁺/calmodulin-dependent coupling of voltage-gated CaV1.2 channels. Elife. 2015 Feb 25; 4. Dixon RE, Moreno CM, Yuan C, Opitz-Araya X, Binder MD, Navedo MF, Santana LF. PMID: 25714924; PMCID: PMC4360655.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    42. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes. J Biol Chem. 2015 Mar 20; 290(12):7918-29. Nieves-Cintrón M, Nystoriak MA, Prada MP, Johnson K, Fayer W, Dell'Acqua ML, Scott JD, Navedo MF. PMID: 25670860; PMCID: PMC4367290.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    43. Mission CaMKIIγ: shuttle calmodulin from membrane to nucleus. Cell. 2014 Oct 09; 159(2):235-7. Malik ZA, Stein IS, Navedo MF, Hell JW. PMID: 25303520; PMCID: PMC7031110.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    44. AKAP5 keeps L-type channels and NFAT on their toes. Cell Rep. 2014 Jun 12; 7(5):1341-1342. Navedo MF, Hell JW. PMID: 24926793; PMCID: PMC7032163.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    45. Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol. 2014 May; 143(5):559-75. Mercado J, Baylie R, Navedo MF, Yuan C, Scott JD, Nelson MT, Brayden JE, Santana LF. PMID: 24778429; PMCID: PMC4003184.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    46. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res. 2014 Feb 14; 114(4):607-15. Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. PMID: 24323672; PMCID: PMC3954117.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    47. Regulation of L-type calcium channel sparklet activity by c-Src and PKC-α. Am J Physiol Cell Physiol. 2013 Sep; 305(5):C568-77. Gulia J, Navedo MF, Gui P, Chao JT, Mercado JL, Santana LF, Davis MJ. PMID: 23804206; PMCID: PMC3761150.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    48. Calcium dynamics in vascular smooth muscle. Microcirculation. 2013 May; 20(4):281-9. Amberg GC, Navedo MF. PMID: 23384444; PMCID: PMC3651748.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    49. Local regulation of L-type Ca²⁺ channel sparklets in arterial smooth muscle. Microcirculation. 2013 May; 20(4):290-8. Navedo MF, Amberg GC. PMID: 23116449; PMCID: PMC3577995.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    50. CaV1.2 sparklets in heart and vascular smooth muscle. J Mol Cell Cardiol. 2013 May; 58:67-76. Navedo MF, Santana LF. PMID: 23220157; PMCID: PMC3678956.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    51. Anchored phosphatases modulate glucose homeostasis. The EMBO Journal. 2012 Nov 28; 31(23):4481-4481. Hinke HS, Navedo NM, Ulman UA, Whiting WJ, Nygren NP, Tian TG, Jimenez-Caliani JA, Langeberg LL, Cirulli CV, Tengholm TA, Dell'Acqua DM, Santana SL, Scott SJ. .
      View in: Publisher Site   Mentions:
    52. Capturing single L-type Ca(2+) channel function with optics. Biochim Biophys Acta. 2013 Jul; 1833(7):1657-64. Nystoriak MA, Nieves-Cintrón M, Navedo MF. PMID: 23124113; PMCID: PMC3574202.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    53. Anchored phosphatases modulate glucose homeostasis. EMBO J. 2012 Oct 17; 31(20):3991-4004. Hinke SA, Navedo MF, Ulman A, Whiting JL, Nygren PJ, Tian G, Jimenez-Caliani AJ, Langeberg LK, Cirulli V, Tengholm A, Dell'Acqua ML, Santana LF, Scott JD. PMID: 22940692; PMCID: PMC3474922.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    54. Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1749-54. Dixon RE, Yuan C, Cheng EP, Navedo MF, Santana LF. PMID: 22307641; PMCID: PMC3277143.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    55. Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2011 Dec; 301(6):H2285-94. Takeda Y, Nystoriak MA, Nieves-Cintrón M, Santana LF, Navedo MF. PMID: 21984539; PMCID: PMC3233819.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    56. Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circ Res. 2011 Jul 22; 109(3):255-61. Cheng EP, Yuan C, Navedo MF, Dixon RE, Nieves-Cintrón M, Scott JD, Santana LF. PMID: 21700933; PMCID: PMC3151468.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    57. Natural inequalities: why some L-type Ca2+ channels work harder than others. J Gen Physiol. 2010 Aug; 136(2):143-7. Santana LF, Navedo MF. PMID: 20660657; PMCID: PMC2912067.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    58. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circ Res. 2010 Sep 17; 107(6):747-56. Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. PMID: 20671242; PMCID: PMC2981172.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    59. Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. Am J Physiol Heart Circ Physiol. 2010 May; 298(5):H1472-83. Zhang J, Ren C, Chen L, Navedo MF, Antos LK, Kinsey SP, Iwamoto T, Philipson KD, Kotlikoff MI, Santana LF, Wier WG, Matteson DR, Blaustein MP. PMID: 20173044; PMCID: PMC2867439.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    60. Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circ Res. 2010 Mar 05; 106(4):748-56. Navedo MF, Cheng EP, Yuan C, Votaw S, Molkentin JD, Scott JD, Santana LF. PMID: 20110531; PMCID: PMC2834417.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    61. Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells. Am J Physiol Cell Physiol. 2010 Feb; 298(2):C211-20. Navedo MF, Takeda Y, Nieves-Cintrón M, Molkentin JD, Santana LF. PMID: 19846755; PMCID: PMC2822492.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    62. Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle. J Mol Cell Cardiol. 2009 Oct; 47(4):436-44. Santana LF, Navedo MF. PMID: 19616004; PMCID: PMC2739251.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    63. The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A. 2008 Oct 07; 105(40):15623-8. Nieves-Cintrón M, Amberg GC, Navedo MF, Molkentin JD, Santana LF. PMID: 18832165; PMCID: PMC2557027.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    64. Functional contribution of alpha3L8' to the neuronal nicotinic alpha3 receptor. J Neurosci Res. 2008 Oct; 86(13):2884-94. Nieves-Cintrón M, Caballero-Rivera D, Silva WI, Navedo MF, Lasalde-Dominicci JA. PMID: 18615639; PMCID: PMC4586081.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    65. Calcium sparklets in arterial smooth muscle. Clin Exp Pharmacol Physiol. 2008 Sep; 35(9):1121-6. Santana LF, Navedo MF, Amberg GC, Nieves-Cintrón M, Votaw VS, Ufret-Vincenty CA. PMID: 18215181; PMCID: PMC5832963.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    66. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circ Res. 2008 Feb 01; 102(2):e1-e11. Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. PMID: 18174462.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    67. Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1359-70. Navedo MF, Amberg GC, Westenbroek RE, Sinnegger-Brauns MJ, Catterall WA, Striessnig J, Santana LF. PMID: 17526649.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    68. Calcium sparklets regulate local and global calcium in murine arterial smooth muscle. J Physiol. 2007 Feb 15; 579(Pt 1):187-201. Amberg GC, Navedo MF, Nieves-Cintrón M, Molkentin JD, Santana LF. PMID: 17158168; PMCID: PMC2075382.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    69. Contribution of valine 7' of TMD2 to gating of neuronal alpha3 receptor subtypes. J Neurosci Res. 2006 Dec; 84(8):1778-88. Nieves-Cintrón M, Caballero-Rivera D, Navedo MF, Lasalde-Dominicci JA. PMID: 17044037.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    70. Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. J Gen Physiol. 2006 Jun; 127(6):611-22. Navedo MF, Amberg GC, Nieves M, Molkentin JD, Santana LF. PMID: 16702354; PMCID: PMC2151539.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    71. Novel beta subunit mutation causes a slow-channel syndrome by enhancing activation and decreasing the rate of agonist dissociation. Mol Cell Neurosci. 2006 May-Jun; 32(1-2):82-90. Navedo MF, Lasalde-Dominicci JA, Báez-Pagán CA, Díaz-Pérez L, Rojas LV, Maselli RA, Staub J, Schott K, Zayas R, Gomez CM. PMID: 16624571; PMCID: PMC4636114.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    72. On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle. J Gen Physiol. 2006 Mar; 127(3):221-3. Amberg GC, Navedo MF, Santana LF. PMID: 16505144; PMCID: PMC2151499.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    73. Constitutively active L-type Ca2+ channels. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):11112-7. Navedo MF, Amberg GC, Votaw VS, Santana LF. PMID: 16040810; PMCID: PMC1180225.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    74. NFATc3 regulates Kv2.1 expression in arterial smooth muscle. J Biol Chem. 2004 Nov 05; 279(45):47326-34. Amberg GC, Rossow CF, Navedo MF, Santana LF. PMID: 15322114.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    75. Tryptophan substitutions reveal the role of nicotinic acetylcholine receptor alpha-TM3 domain in channel gating: differences between Torpedo and muscle-type AChR. Biochemistry. 2004 Jan 13; 43(1):78-84. Navedo M, Nieves M, Rojas L, Lasalde-Dominicci JA. PMID: 14705933.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    76. Novel delta subunit mutation in slow-channel syndrome causes severe weakness by novel mechanisms. Ann Neurol. 2002 Jan; 51(1):102-12. Gomez CM, Maselli RA, Vohra BP, Navedo M, Stiles JR, Charnet P, Schott K, Rojas L, Keesey J, Verity A, Wollmann RW, Lasalde-Dominicci J. PMID: 11782989; PMCID: PMC4841278.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
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